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Xinhong Chen - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ding X, Chen X, Sullivan EE, Shay TF, Gradinaru V. Fast, accurate ranking of engineered proteins by target binding propensity using structure modeling. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 38582966 DOI: 10.1016/j.ymthe.2024.04.003  0.701
2023 Coughlin GM, Borsos M, Appling N, Barcelona BH, Mayfield AMH, Mackey ED, Eser RA, Chen X, Kumar SR, Gradinaru V. Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Biorxiv : the Preprint Server For Biology. PMID 38187707 DOI: 10.1101/2023.12.23.573214  0.579
2023 Chuapoco MR, Flytzanis NC, Goeden N, Christopher Octeau J, Roxas KM, Chan KY, Scherrer J, Winchester J, Blackburn RJ, Campos LJ, Man KNM, Sun J, Chen X, Lefevre A, Singh VP, et al. Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain. Nature Nanotechnology. PMID 37430038 DOI: 10.1038/s41565-023-01419-x  0.653
2023 Campos LJ, Arokiaraj CM, Chuapoco MR, Chen X, Goeden N, Gradinaru V, Fox AS. Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system. Current Research in Neurobiology. 4: 100086. PMID 37397806 DOI: 10.1016/j.crneur.2023.100086  0.607
2023 Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nature Communications. 14: 3345. PMID 37291094 DOI: 10.1038/s41467-023-38582-7  0.769
2023 Shay TF, Sullivan EE, Ding X, Chen X, Ravindra Kumar S, Goertsen D, Brown D, Crosby A, Vielmetter J, Borsos M, Wolfe DA, Lam AW, Gradinaru V. Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances. 9: eadg6618. PMID 37075114 DOI: 10.1126/sciadv.adg6618  0.758
2023 Chuapoco M, Flytzanis N, Goeden N, Octeau J, Roxas K, Chan K, Scherrer J, Winchester J, Blackburn R, Campos L, Man KN, Sun J, Chen X, Lefevre A, Singh V, et al. Intravenous functional gene transfer throughout the brain of non-human primates using AAV. Research Square. PMID 36789432 DOI: 10.21203/rs.3.rs-1370972/v1  0.652
2023 Chen X, Wolfe DA, Sivadasan Bindu D, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan E, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner V, Campos LJ, Mich J, Monet D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Biorxiv : the Preprint Server For Biology. PMID 36711773 DOI: 10.1101/2023.01.12.523844  0.769
2023 Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang AZ, Gradinaru V. Spatial transcriptomics for profiling the tropism of viral vectors in tissues. Nature Biotechnology. PMID 36702899 DOI: 10.1038/s41587-022-01648-w  0.619
2022 Chen X, Ravindra Kumar S, Adams CD, Yang D, Wang T, Wolfe DA, Arokiaraj CM, Ngo V, Campos LJ, Griffiths JA, Ichiki T, Mazmanian SK, Osborne PB, Keast JR, Miller CT, et al. Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems. Neuron. PMID 35643078 DOI: 10.1016/j.neuron.2022.05.003  0.6
2022 Challis RC, Ravindra Kumar S, Chen X, Goertsen D, Coughlin GM, Hori AM, Chuapoco MR, Otis TS, Miles TF, Gradinaru V. Adeno-Associated Virus Toolkit to Target Diverse Brain Cells. Annual Review of Neuroscience. PMID 35440143 DOI: 10.1146/annurev-neuro-111020-100834  0.762
2021 Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V. Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses. Cell Reports. 36: 109744. PMID 34592157 DOI: 10.1016/j.celrep.2021.109744  0.554
2021 Cho JR, Chen X, Kahan A, Robinson JE, Wagenaar DA, Gradinaru V. Dorsal raphe dopamine neurons signal motivational salience dependent on internal state, expectation, and behavioral context. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33563725 DOI: 10.1523/JNEUROSCI.2690-20.2021  0.553
2020 Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, et al. Negative feedback control of neuronal activity by microglia. Nature. PMID 32999463 DOI: 10.1038/s41586-020-2777-8  0.707
2020 Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V. Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. Nature Methods. PMID 32313222 DOI: 10.1038/S41592-020-0799-7  0.755
2019 Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM. A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. Science (New York, N.Y.). 366: 1008-1012. PMID 31754002 DOI: 10.1126/Science.Aay1186  0.588
2019 Siciliano C, Noamany H, Chen X, Leible D, Brown A, Chang C, Lee J, Wang J, Vernon A, Weele CV, Kimchi E, Heiman M, Tye K. S207. Cortical-Brainstem Projections Gate Compulsive Alcohol Drinking Biological Psychiatry. 85: S377. DOI: 10.1016/J.Biopsych.2019.03.958  0.564
2017 Huang J, Feng Y, Chen X, Li W, Xue L. Myc inhibits JNK-mediated cell death in vivo. Apoptosis : An International Journal On Programmed Cell Death. PMID 28150056 DOI: 10.1007/S10495-016-1340-4  0.487
2016 Wang X, Zhao Y, Hu Y, Ren P, Sun Y, Guo X, Huang X, Zhu Y, Chen X, Feng Y, Xue L. Establishment of a AD model. Journal of Biological Methods. 3: e43. PMID 31453210 DOI: 10.14440/jbm.2016.61  0.425
2016 Zhuang L, Sun Y, Hu M, Wu C, La X, Chen X, Feng Y, Wang X, Hu Y, Xue L. Or47b plays a role in Drosophila males' preference for younger mates. Open Biology. 6. PMID 27278650 DOI: 10.1098/Rsob.160086  0.465
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