G. Yancey Gillespie, Ph.D. - Publications

Affiliations: 
Immunology, Surgery University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
cytosine deaminase, UPRT, PNP; HSV that include TNFa, IL-2, IL-4, IL-5, IL-10, IL12, IL-16
Website:
http://www.uab.edu/medicine/immunology/faculty/100-gillespie

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Stackhouse CT, Anderson JC, Yue Z, Nguyen T, Eustace NJ, Langford CP, Wang J, Rowland Iv JR, Xing C, Mikhail FM, Cui X, Alrefai H, Bash RE, Lee KJ, Yang ES, ... ... Gillespie GY, et al. An in vivo model of glioblastoma radiation resistance identifies long non-coding RNAs and targetable kinases. Jci Insight. PMID 35852875 DOI: 10.1172/jci.insight.148717  0.303
2021 Boyd NH, Tran AN, Bernstock JD, Etminan T, Jones AB, Gillespie GY, Friedman GK, Hjelmeland AB. Glioma stem cells and their roles within the hypoxic tumor microenvironment. Theranostics. 11: 665-683. PMID 33391498 DOI: 10.7150/thno.41692  0.314
2020 Chambers MR, Bentley RT, Crossman DK, Foote JB, Koehler JW, Markert JM, Omar NB, Platt SR, Self DM, Shores A, Sorjonen DC, Waters AM, Yanke AB, Gillespie GY. The One Health Consortium: Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Combination With a Checkpoint Inhibitor in Canine Patients With Sporadic High Grade Gliomas. Frontiers in Surgery. 7: 59. PMID 33005623 DOI: 10.3389/Fsurg.2020.00059  0.434
2019 Bernstock JD, Vicario N, Rong L, Valdes PA, Choi BD, Chen JA, DiToro D, Osorio DS, Kachurak K, Gessler F, Johnston JM, Atkinson TP, Whitley RJ, Bag AK, Gillespie GY, et al. A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition. Oncoimmunology. 8: e1678921. PMID 31741780 DOI: 10.1080/2162402X.2019.1678921  0.413
2019 Stackhouse CT, Rowland JR, Shevin RS, Singh R, Gillespie GY, Willey CD. A Novel Assay for Profiling GBM Cancer Model Heterogeneity and Drug Screening. Cells. 8. PMID 31336733 DOI: 10.3390/Cells8070702  0.332
2019 Totsch SK, Schlappi C, Kang KD, Ishizuka AS, Lynn GM, Fox B, Beierle EA, Whitley RJ, Markert JM, Gillespie GY, Bernstock JD, Friedman GK. Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance. Oncogene. PMID 31289361 DOI: 10.1038/S41388-019-0870-Y  0.394
2019 Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, ... ... Gillespie GY, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 36: 51-67.e7. PMID 31287992 DOI: 10.1016/J.Ccell.2019.06.002  0.336
2019 Bernstock JD, Vicario N, Li R, Nan L, Totsch SK, Schlappi C, Gessler F, Han X, Parenti R, Beierle EA, Whitley RJ, Aban I, Gillespie GY, Markert JM, Friedman GK. Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice. Cancer Gene Therapy. PMID 30918335 DOI: 10.1038/S41417-019-0091-0  0.378
2019 Stackhouse C, Gillespie GY, Willey C. Dres-04. Long Non-Coding Rnas In Glioblastoma Tumor Recurrence And Therapy Resistance Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.292  0.315
2018 Friedman GK, Bernstock JD, Chen D, Nan L, Moore BP, Kelly VM, Youngblood SL, Langford CP, Han X, Ring EK, Beierle EA, Gillespie GY, Markert JM. Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression. Scientific Reports. 8: 13930. PMID 30224769 DOI: 10.1038/S41598-018-32353-X  0.413
2018 Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell. 33: 1004-1016.e5. PMID 29894688 DOI: 10.1016/J.Ccell.2018.05.006  0.367
2018 Gilbert AN, Anderson JC, Duarte CW, Shevin RS, Langford CP, Singh R, Gillespie GY, Willey CD. Combinatorial Drug Testing in 3D Microtumors Derived from GBM Patient-Derived Xenografts Reveals Cytotoxic Synergy in Pharmacokinomics-informed Pathway Interactions. Scientific Reports. 8: 8412. PMID 29849102 DOI: 10.1038/S41598-018-26840-4  0.397
2018 Kim J, Stone JK, Li J, Richard A, Vukadin L, Gillespie GY, Sobol RW, Lim S, Ahn EE. Abstract LB-204: SON controls the oncogenic alternative splicing program in glioblastoma by regulating PTBP1/2 switch and RBFOX2 activity Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-204  0.314
2017 Boyd NH, Walker K, Fried J, Hackney JR, McDonald PC, Benavides GA, Spina R, Audia A, Scott SE, Libby CJ, Tran AN, Bevensee MO, Griguer C, Nozell S, Gillespie GY, et al. Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. Jci Insight. 2. PMID 29263302 DOI: 10.1172/Jci.Insight.92928  0.458
2017 Ghonime MG, Jackson J, Shah A, Roth J, Li M, Saunders U, Coleman J, Gillespie GY, Markert JM, Cassady KA. Chimeric HCMV/HSV-1 and Δγ134.5 oncolytic herpes simplex virus elicit immune mediated antigliomal effect and antitumor memory. Translational Oncology. 11: 86-93. PMID 29216507 DOI: 10.1016/J.Tranon.2017.10.005  0.448
2017 Gilbert AN, Walker K, Tran AN, Boyd NH, Gillespie GY, Singh RK, Hjelmeland AB. Modeling Physiologic Microenvironments in Three-Dimensional Microtumors Maintains Brain Tumor Initiating Cells. Journal of Cancer Stem Cell Research. 5. PMID 29075651 DOI: 10.14343/JCSCR.2017.5e1004  0.367
2017 Ring EK, Li R, Moore BP, Nan L, Kelly VM, Han X, Beierle EA, Markert JM, Leavenworth JW, Gillespie GY, Friedman GK. Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002. Molecular Therapy Oncolytics. 7: 27-36. PMID 29034313 DOI: 10.1016/J.Omto.2017.09.003  0.367
2017 Waters AM, Johnston JM, Reddy AT, Fiveash J, Madan-Swain A, Kachurak K, Bag AK, Gillespie GY, Markert JM, Friedman GK. Rationale and Design of a Phase 1 Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors. Human Gene Therapy. Clinical Development. 28: 7-16. PMID 28319448 DOI: 10.1089/Humc.2017.002  0.429
2017 Waters AM, Johnston JM, Reddy AT, Fiveash J, Madan-Swain A, Kachurak K, Bag AK, Gillespie GY, Markert JM, Friedman GK. Rationale and Design of a Phase I Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors. Human Gene Therapy. Clinical Development. PMID 28253733 DOI: 10.1089/hum.2017.002  0.321
2016 Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, ... ... Gillespie GY, et al. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Cancer Cell. 30: 891-908. PMID 27960086 DOI: 10.1016/J.Ccell.2016.11.003  0.372
2016 Ahluwalia MS, Bou-Anak S, Burgett ME, Sarmey N, Khosla D, Dahiya S, Weil RJ, Bae E, Huang P, McGraw M, Grove LM, Olman MA, Prayson RA, Suh JH, Gillespie GY, et al. Correlation of higher levels of soluble TNF-R1 with a shorter survival, independent of age, in recurrent glioblastoma. Journal of Neuro-Oncology. PMID 27858267 DOI: 10.1007/S11060-016-2319-2  0.308
2016 Ring EK, Markert JM, Gillespie GY, Friedman GK. Checkpoint Proteins in Pediatric Brain and Extracranial Solid Tumors: Opportunities for Immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27836863 DOI: 10.1158/1078-0432.Ccr-16-1829  0.42
2016 Thomas ED, Meza-Perez S, Bevis KS, Randall TD, Gillespie GY, Langford C, Alvarez RD. IL-12 Expressing oncolytic herpes simplex virus promotes anti-tumor activity and immunologic control of metastatic ovarian cancer in mice. Journal of Ovarian Research. 9: 70. PMID 27784340 DOI: 10.1186/S13048-016-0282-3  0.405
2016 Waters AM, Stafman LL, Garner EF, Mruthyunjayappa S, Stewart JE, Friedman GK, Coleman JM, Markert JM, Gillespie GY, Beierle EA. Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. Translational Oncology. 9: 419-430. PMID 27751346 DOI: 10.1016/J.Tranon.2016.07.008  0.455
2016 Bauer DF, Pereboeva L, Gillespie GY, Cloud GA, Elzafarany O, Langford C, Markert JM, Jr LS. Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma. Journal of Immunology Research. 2016: 2568125. PMID 27610392 DOI: 10.1155/2016/2568125  0.378
2016 Graham CD, Kaza N, Klocke BJ, Gillespie GY, Shevde LA, Carroll SL, Roth KA. Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma. Journal of Neuropathology and Experimental Neurology. PMID 27516117 DOI: 10.1093/Jnen/Nlw071  0.425
2016 Gilbert AN, Shevin RS, Anderson JC, Langford CP, Eustace N, Gillespie GY, Singh R, Willey CD. Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing. Journal of Visualized Experiments : Jove. PMID 27341166 DOI: 10.3791/54026  0.383
2016 Patel DM, Foreman PM, Nabors LB, Riley KO, Gillespie GY, Markert JM. Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma. Human Gene Therapy. Clinical Development. 27: 69-78. PMID 27314913 DOI: 10.1089/humc.2016.031  0.345
2016 Ring E, Moore B, Nan L, Etminan T, Markert J, Gillespie GY, Friedman G. Pcm-21Expression Of Immune Checkpoint Proteins In Patient-Derived Pediatric Brain Tumor Xenografts Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now080.21  0.413
2016 Ring E, Moore B, Nan L, Etminan T, Markert J, Gillespie GY, Friedman G. Pcm-09Comparison Of The Sensitivities Of Pediatric High-Grade Brain Tumor Versus Adult Glioblastoma Xenografts To Engineered Oncolytic Herpes Simplex Virotherapy Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now080.09  0.354
2016 Reddy A, Johnston J, Madan-Swain A, Fiveash J, Bag A, Gillespie GY, Markert J, Friedman G. EPT-10PHASE I CLINICAL TRIAL OF HSV G207 ALONE OR WITH A SINGLE RADIATION DOSE IN CHILDREN WITH RECURRENT SUPRATENTORIAL BRAIN TUMORS (NCT02457845) Neuro-Oncology. 18: iii25.5-iii26. DOI: 10.1093/Neuonc/Now069.09  0.312
2015 Anderson JC, Taylor RB, Fiveash JB, de Wijn R, Gillespie GY, Willey CD. KINOMIC ALTERATIONS IN ATYPICAL MENINGIOMA. Medical Research Archives. 2015. PMID 27158663 DOI: 10.18103/Mra.V0I3.104  0.332
2015 Dobbins GC, Ugai H, Curiel DT, Gillespie GY. A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents. Plos One. 10: e0145272. PMID 26689910 DOI: 10.1371/Journal.Pone.0145272  0.507
2015 Lobo MR, Kukino A, Tran H, Schabel MC, Springer CS, Gillespie GY, Grafe MR, Woltjer RL, Pike MM. Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma. Plos One. 10: e0144488. PMID 26645398 DOI: 10.1371/Journal.Pone.0144488  0.385
2015 Friedman GK, Moore BP, Nan L, Kelly VM, Etminan T, Langford CP, Xu H, Han X, Markert JM, Beierle EA, Gillespie GY. Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses. Neuro-Oncology. PMID 26188016 DOI: 10.1093/Neuonc/Nov123  0.355
2015 Tilson SG, Haley EM, Triantafillu UL, Dozier DA, Langford CP, Gillespie GY, Kim Y. ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells. Plos One. 10: e0132823. PMID 26167936 DOI: 10.1371/Journal.Pone.0132823  0.382
2015 Warram JM, de Boer E, Korb M, Hartman Y, Kovar J, Markert JM, Gillespie GY, Rosenthal EL. Fluorescence-guided resection of experimental malignant glioma using cetuximab-IRDye 800CW. British Journal of Neurosurgery. 1-9. PMID 26073144 DOI: 10.3109/02688697.2015.1056090  0.343
2015 Beck BH, Kim H, O'Brien R, Jadus MR, Gillespie GY, Cloud GA, Hoa NT, Langford CP, Lopez RD, Harkins LE, Lamb LS. Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma. Plos One. 10: e0122387. PMID 25955158 DOI: 10.1371/Journal.Pone.0122387  0.407
2015 Oliva CR, Markert T, Gillespie GY, Griguer CE. Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas. Oncotarget. 6: 4330-44. PMID 25726526 DOI: 10.18632/Oncotarget.3015  0.393
2015 Willey CD, Gilbert AN, Shevin R, Langford CP, Duarte CW, Singh R, Anderson JC, Gillespie GY. Abstract A16: Combinatorial drug testing using 3D microtumors derived from GBM PDX reveals cytotoxic synergisms in pharmacokinomics-informed pathway interactions Brain. 75. DOI: 10.1158/1538-7445.Brain15-A16  0.396
2015 Willey CD, Gilbert AN, Shevin R, Langford CP, Singh R, Anderson JC, Gillespie GY. Abstract 312: Profiling drug sensitivity and kinomic pathways utilizing a novel human tumor derived MicroTumor assay Cancer Research. 75: 312-312. DOI: 10.1158/1538-7445.Am2015-312  0.406
2015 Friedman G, Nan L, Moore B, Etminan T, Orr B, Chewning J, Crossman D, Gillespie GY. PM-05 * TUMOR LOCATION REMODELS TRANSCRIPTOMIC PROFILES IN A PEDIATRIC MEDULLOBLASTOMA XENOGRAFT Neuro-Oncology. 17: iii32-iii32. DOI: 10.1093/Neuonc/Nov061.127  0.428
2014 Lobo MR, Wang X, Gillespie GY, Woltjer RL, Pike MM. Combined efficacy of cediranib and quinacrine in glioma is enhanced by hypoxia and causally linked to autophagic vacuole accumulation. Plos One. 9: e114110. PMID 25490024 DOI: 10.1371/Journal.Pone.0114110  0.371
2014 Han X, Zhang W, Yang X, Wheeler CG, Langford CP, Wu L, Filippova N, Friedman GK, Ding Q, Fathallah-Shaykh HM, Gillespie GY, Nabors LB. The role of Src family kinases in growth and migration of glioma stem cells. International Journal of Oncology. 45: 302-10. PMID 24819299 DOI: 10.3892/Ijo.2014.2432  0.345
2014 Han X, Li R, Zhang W, Yang X, Wheeler CG, Friedman GK, Province P, Ding Q, You Z, Fathallah-Shaykh HM, Gillespie GY, Zhao X, King PH, Nabors LB. Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro. Journal of Neuro-Oncology. 118: 61-72. PMID 24664369 DOI: 10.1007/S11060-014-1419-0  0.44
2014 Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, ... ... Gillespie GY, et al. A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1048-55. PMID 24572293 DOI: 10.1038/Mt.2014.22  0.327
2014 Megison ML, Gillory LA, Stewart JE, Nabers HC, Mroczek-Musulman E, Waters AM, Coleman JM, Kelly V, Markert JM, Gillespie GY, Friedman GK, Beierle EA. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors. Plos One. 9: e86843. PMID 24497984 DOI: 10.1371/Journal.Pone.0086843  0.431
2013 Gillory LA, Megison ML, Stewart JE, Mroczek-Musulman E, Nabers HC, Waters AM, Kelly V, Coleman JM, Markert JM, Gillespie GY, Friedman GK, Beierle EA. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma. Plos One. 8: e77753. PMID 24130898 DOI: 10.1371/Journal.Pone.0077753  0.443
2013 Lobo MR, Green SC, Schabel MC, Gillespie GY, Woltjer RL, Pike MM. Quinacrine synergistically enhances the antivascular and antitumor efficacy of cediranib in intracranial mouse glioma. Neuro-Oncology. 15: 1673-83. PMID 24092859 DOI: 10.1093/Neuonc/Not119  0.42
2013 Knight A, Arnouk H, Britt W, Gillespie GY, Cloud GA, Harkins L, Su Y, Lowdell MW, Lamb LS. CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells. Plos One. 8: e68729. PMID 23950874 DOI: 10.1371/Journal.Pone.0068729  0.364
2013 Griguer CE, Cantor AB, Fathallah-Shaykh HM, Gillespie GY, Gordon AS, Markert JM, Radovanovic I, Clement-Schatlo V, Shannon CN, Oliva CR. Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme. Plos One. 8: e61035. PMID 23593382 DOI: 10.1371/Journal.Pone.0061035  0.362
2013 Friedman GK, Raborn J, Kelly VM, Cassady KA, Markert JM, Gillespie GY. Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy. Frontiers in Oncology. 3: 28. PMID 23450706 DOI: 10.3389/Fonc.2013.00028  0.342
2013 Lamb LS, Bowersock J, Dasgupta A, Gillespie GY, Su Y, Johnson A, Spencer HT. Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy. Plos One. 8: e51805. PMID 23326319 DOI: 10.1371/Journal.Pone.0051805  0.405
2013 Pressey JG, Haas MC, Pressey CS, Kelly VM, Parker JN, Gillespie GY, Friedman GK. CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV. Pediatric Blood & Cancer. 60: 45-52. PMID 22408058 DOI: 10.1002/Pbc.24117  0.346
2012 Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Gillespie GY, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327  0.307
2012 Jarboe JS, Anderson JC, Duarte CW, Mehta T, Nowsheen S, Hicks PH, Whitley AC, Rohrbach TD, McCubrey RO, Chiu S, Burleson TM, Bonner JA, Gillespie GY, Yang ES, Willey CD. MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3030-41. PMID 22619307 DOI: 10.1158/1078-0432.CCR-11-3091  0.308
2012 Friedman GK, Cassady KA, Beierle EA, Markert JM, Gillespie GY. Targeting pediatric cancer stem cells with oncolytic virotherapy. Pediatric Research. 71: 500-10. PMID 22430386 DOI: 10.1038/Pr.2011.58  0.412
2012 Duarte CW, Willey CD, Zhi D, Cui X, Harris JJ, Vaughan LK, Mehta T, McCubrey RO, Khodarev NN, Weichselbaum RR, Gillespie GY. Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. Plos One. 7: e29653. PMID 22242177 DOI: 10.1371/Journal.Pone.0029653  0.338
2012 Beck B, Lopez RD, Gillespie GY, Kim H, Cloud G, Pereboeva L, Lamb LS. Peripheral Blood γδ T Cell Response to High-Grade Glioma: Implications for Localized Adoptive Immunotherapy Blood. 120: 4114-4114. DOI: 10.1182/Blood.V120.21.4114.4114  0.406
2012 Beck B, Gillespie GY, Lopez RD, Cloud GA, Langford C, Kim H, Harkins L, Lamb LS. Abstract 530: Circulating γδ T cells are activated and depleted during progression of high-grade gliomas: Implications for γδ T cells therapy of GBM Cancer Research. 72: 530-530. DOI: 10.1158/1538-7445.Am2012-530  0.406
2012 Lobo MR, Huang ET, Kurre P, Schabel MC, Gillespie GY, Pike MM. Abstract 1905: Autophagy inhibitor quinacrine synergistically enhances anti-angiogenic efficacy of Cediranib in intracranial mouse glioma Cancer Research. 72: 1905-1905. DOI: 10.1158/1538-7445.Am2012-1905  0.342
2012 Gillory LA, Megison ML, Stewart JE, Nabers HC, Friedman GK, Markert JM, Gillespie GY, Beierle EA. Oncolytic herpes simplex virus and radiation combination therapy results in a systemic immune response to inhibit neuroblastoma tumor growth Journal of the American College of Surgeons. 215: S69-S70. DOI: 10.1016/J.Jamcollsurg.2012.06.192  0.362
2011 McFarland BC, Ma JY, Langford CP, Gillespie GY, Yu H, Zheng Y, Nozell SE, Huszar D, Benveniste EN. Therapeutic potential of AZD1480 for the treatment of human glioblastoma. Molecular Cancer Therapeutics. 10: 2384-93. PMID 22027691 DOI: 10.1158/1535-7163.MCT-11-0480  0.332
2011 Oliva CR, Moellering DR, Gillespie GY, Griguer CE. Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production. Plos One. 6: e24665. PMID 21931801 DOI: 10.1371/Journal.Pone.0024665  0.314
2011 Wang D, Olman MA, Stewart J, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, et al. Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity. Plos One. 6: e19629. PMID 21602932 DOI: 10.1371/Journal.Pone.0019629  0.457
2011 Filippova N, Yang X, Wang Y, Gillespie GY, Langford C, King PH, Wheeler C, Nabors LB. The RNA-binding protein HuR promotes glioma growth and treatment resistance. Molecular Cancer Research : McR. 9: 648-59. PMID 21498545 DOI: 10.1158/1541-7786.Mcr-10-0325  0.461
2011 Friedman GK, Gillespie GY. Cancer Stem Cells and Pediatric Solid Tumors. Cancers. 3: 298-318. PMID 21394230 DOI: 10.3390/Cancers3010298  0.428
2011 Sun M, Song L, Zhou T, Gillespie GY, Jope RS. The role of DDX3 in regulating Snail. Biochimica Et Biophysica Acta. 1813: 438-47. PMID 21237216 DOI: 10.1016/J.Bbamcr.2011.01.003  0.339
2011 Bryant NL, Gillespie GY, Lopez RD, Markert JM, Cloud GA, Langford CP, Arnouk H, Su Y, Haines HL, Suarez-Cuervo C, Lamb LS. Preclinical evaluation of ex vivo expanded/activated γδ T cells for immunotherapy of glioblastoma multiforme. Journal of Neuro-Oncology. 101: 179-88. PMID 20532954 DOI: 10.1007/S11060-010-0245-2  0.415
2011 Gillory LA, Haas MC, Friedman GK, Stewart JE, Parker JN, Markert JM, Gillespie GY, Beierle EA. Combination treatment with genetically altered oncolytic herpes simplex virus and low-dose irradiation inhibits neuroblastoma tumor growth Journal of the American College of Surgeons. 213: S76. DOI: 10.1016/J.Jamcollsurg.2011.06.178  0.366
2010 Oliva CR, Nozell SE, Diers A, McClugage SG, Sarkaria JN, Markert JM, Darley-Usmar VM, Bailey SM, Gillespie GY, Landar A, Griguer CE. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of Biological Chemistry. 285: 39759-67. PMID 20870728 DOI: 10.1074/Jbc.M110.147504  0.338
2009 Friedman GK, Pressey JG, Reddy AT, Markert JM, Gillespie GY. Herpes simplex virus oncolytic therapy for pediatric malignancies. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1125-35. PMID 19367259 DOI: 10.1038/Mt.2009.73  0.377
2009 Kaliberova LN, Krendelchtchikova V, Harmon DK, Stockard CR, Petersen AS, Markert JM, Gillespie GY, Grizzle WE, Buchsbaum DJ, Kaliberov SA. CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma. Cancer Gene Therapy. 16: 794-805. PMID 19363468 DOI: 10.1038/Cgt.2009.23  0.501
2009 Bryant NL, Suarez-Cuervo C, Gillespie GY, Markert JM, Nabors LB, Meleth S, Lopez RD, Lamb LS. Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma. Neuro-Oncology. 11: 357-67. PMID 19211933 DOI: 10.1215/15228517-2008-111  0.373
2008 Griguer CE, Oliva CR, Gobin E, Marcorelles P, Benos DJ, Lancaster JR, Gillespie GY. CD133 is a marker of bioenergetic stress in human glioma. Plos One. 3: e3655. PMID 18985161 DOI: 10.1371/Journal.Pone.0003655  0.326
2008 Brantley EC, Nabors LB, Gillespie GY, Choi YH, Palmer CA, Harrison K, Roarty K, Benveniste EN. Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4694-704. PMID 18676737 DOI: 10.1158/1078-0432.Ccr-08-0618  0.367
2008 Fiveash JB, Gillespie GY, Oliver PG, Zhou T, Belenky ML, Buchsbaum DJ. Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5. International Journal of Radiation Oncology, Biology, Physics. 71: 507-16. PMID 18474311 DOI: 10.1016/J.Ijrobp.2008.02.005  0.6
2008 Suswam E, Li Y, Zhang X, Gillespie GY, Li X, Shacka JJ, Lu L, Zheng L, King PH. Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells. Cancer Research. 68: 674-82. PMID 18245466 DOI: 10.1158/0008-5472.Can-07-2751  0.382
2008 Fiveash J, Buchsbaum D, Gillespie GY. In Reply to Dr. Speer International Journal of Radiation Oncology Biology Physics. 72: 1274. DOI: 10.1016/J.Ijrobp.2008.07.045  0.435
2007 Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS. Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models. Neuro-Oncology. 9: 280-90. PMID 17522331 DOI: 10.1215/15228517-2007-017  0.469
2007 Radbill AE, Reddy AT, Markert JM, Wyss JM, Pike MM, Akella NS, Bharara N, Gillespie GY. Effects of G207, a conditionally replication-competent oncolytic herpes simplex virus, on the developing mammalian brain. Journal of Neurovirology. 13: 118-29. PMID 17505980 DOI: 10.1080/13550280601187177  0.381
2007 Kaliberov SA, Market JM, Gillespie GY, Krendelchtchikova V, Della Manna D, Sellers JC, Kaliberova LN, Black ME, Buchsbaum DJ. Mutation of Escherichia coli cytosine deaminase significantly enhances molecular chemotherapy of human glioma. Gene Therapy. 14: 1111-9. PMID 17495948 DOI: 10.1038/Sj.Gt.3302965  0.506
2007 Shah AC, Parker JN, Gillespie GY, Lakeman FD, Meleth S, Markert JM, Cassady KA. Enhanced antiglioma activity of chimeric HCMV/HSV-1 oncolytic viruses. Gene Therapy. 14: 1045-54. PMID 17429445 DOI: 10.1038/Sj.Gt.3302942  0.324
2007 Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. Journal of Proteome Research. 6: 559-70. PMID 17269713 DOI: 10.1021/Pr060240Z  0.361
2007 Tang Y, Han T, Everts M, Zhu ZB, Gillespie GY, Curiel DT, Wu H. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Therapy. 14: 523-32. PMID 17167498 DOI: 10.1038/Sj.Gt.3302888  0.367
2007 Guffey MB, Parker JN, Luckett WS, Gillespie GY, Meleth S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors. Cancer Gene Therapy. 14: 45-56. PMID 16990846 DOI: 10.1038/Sj.Cgt.7700978  0.355
2007 Griguer CE, Oliva CR, Gillespie GY, Gobin E, Marcorelles P, Yancey Gillespie G. Pharmacologic manipulations of mitochondrial membrane potential (DeltaPsim) selectively in glioma cells. Journal of Neuro-Oncology. 81: 9-20. PMID 16862448 DOI: 10.1007/S11060-006-9201-6  0.359
2006 Markert JM, Parker JN, Buchsbaum DJ, Grizzle WE, Gillespie GY, Whitley RJ. Oncolytic HSV-1 for the treatment of brain tumours. Herpes : the Journal of the Ihmf. 13: 66-71. PMID 17147910  0.461
2006 Shah AC, Price KH, Parker JN, Samuel SL, Meleth S, Cassady KA, Gillespie GY, Whitley RJ, Markert JM. Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors. Journal of Virology. 80: 7308-15. PMID 16840311 DOI: 10.1128/Jvi.00725-06  0.44
2006 Grunda JM, Nabors LB, Palmer CA, Chhieng DC, Steg A, Mikkelsen T, Diasio RB, Zhang K, Allison D, Grizzle WE, Wang W, Gillespie GY, Johnson MR. Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM). Journal of Neuro-Oncology. 80: 261-74. PMID 16773218 DOI: 10.1007/S11060-006-9191-4  0.346
2006 Vila-Carriles WH, Kovacs GG, Jovov B, Zhou ZH, Pahwa AK, Colby G, Esimai O, Gillespie GY, Mapstone TB, Markert JM, Fuller CM, Bubien JK, Benos DJ. Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells. The Journal of Biological Chemistry. 281: 19220-32. PMID 16704974 DOI: 10.1074/Jbc.M603100200  0.386
2006 Kim KJ, Wang L, Su YC, Gillespie GY, Salhotra A, Lal B, Laterra J. Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1292-8. PMID 16489086 DOI: 10.1158/1078-0432.Ccr-05-1793  0.425
2006 Griguer CE, Oliva CR, Kelley EE, Giles GI, Lancaster JR, Gillespie GY. Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells. Cancer Research. 66: 2257-63. PMID 16489029 DOI: 10.1158/0008-5472.Can-05-3364  0.323
2006 Akella NS, Ding Q, Menegazzo I, Wang W, Gillespie GY, Grammer JR, Gladson CL, Nabors LB. A novel technique to quantify glioma tumor invasion using serial microscopy sections. Journal of Neuroscience Methods. 153: 183-9. PMID 16406041 DOI: 10.1016/J.Jneumeth.2005.10.026  0.417
2006 Chen SH, Gillespie GY, Benveniste EN. Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases. Glia. 53: 191-200. PMID 16206166 DOI: 10.1002/Glia.20264  0.365
2005 Griguer CE, Oliva CR, Gillespie GY. Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines. Journal of Neuro-Oncology. 74: 123-33. PMID 16193382 DOI: 10.1007/S11060-004-6404-6  0.345
2005 Chung WJ, Lyons SA, Nelson GM, Hamza H, Gladson CL, Gillespie GY, Sontheimer H. Inhibition of cystine uptake disrupts the growth of primary brain tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7101-10. PMID 16079392 DOI: 10.1523/Jneurosci.5258-04.2005  0.394
2005 Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro-Oncology. 7: 213-24. PMID 16053696 DOI: 10.1215/S1152851705000074  0.411
2005 Stettner MR, Wang W, Nabors LB, Bharara S, Flynn DC, Grammer JR, Gillespie GY, Gladson CL. Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Research. 65: 5535-43. PMID 15994925 DOI: 10.1158/0008-5472.Can-04-3688  0.387
2005 Bharara S, Sorscher EJ, Gillespie GY, Lindsey JR, Hong JS, Curlee KV, Allan PW, Gadi VK, Alexander SA, Secrist JA, Parker WB, Waud WR. Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy. Human Gene Therapy. 16: 339-47. PMID 15812229 DOI: 10.1089/Hum.2005.16.339  0.435
2005 Kovacs GG, Zsembery A, Anderson SJ, Komlosi P, Gillespie GY, Bell PD, Benos DJ, Fuller CM. Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes. American Journal of Physiology. Cell Physiology. 289: C361-71. PMID 15800052 DOI: 10.1152/Ajpcell.00280.2004  0.332
2005 Shen S, Khazaeli MB, Gillespie GY, Alvarez VL. Radiation dosimetry of 131I-chlorotoxin for targeted radiotherapy in glioma-bearing mice. Journal of Neuro-Oncology. 71: 113-9. PMID 15690125 DOI: 10.1007/S11060-004-0890-4  0.364
2005 Parker JN, Meleth S, Hughes KB, Gillespie GY, Whitley RJ, Markert JM. Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12. Cancer Gene Therapy. 12: 359-68. PMID 15678154 DOI: 10.1038/Sj.Cgt.7700784  0.423
2005 Fiveash JB, Buchsbaum DJ, Gillespie GY. TRAIL death receptor therapy for malignant glioma Journal of Clinical Oncology. 23: 3187-3187. DOI: 10.1200/Jco.2005.23.16_Suppl.3187  0.495
2004 Yamini B, Yu X, Gillespie GY, Kufe DW, Weichselbaum RR. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Research. 64: 6381-4. PMID 15374943 DOI: 10.1158/0008-5472.Can-04-2117  0.351
2004 Bubien JK, Ji HL, Gillespie GY, Fuller CM, Markert JM, Mapstone TB, Benos DJ. Cation selectivity and inhibition of malignant glioma Na+ channels by Psalmotoxin 1. American Journal of Physiology. Cell Physiology. 287: C1282-91. PMID 15253892 DOI: 10.1152/Ajpcell.00077.2004  0.327
2004 Markert JM, Guffey MB, Manna DD, Buchsbaum DJ, Price KH, Langford CP, Gillespie GY. 1031. Improved Anti-Brain Tumor Efficacy of |[Delta]||[gamma]|134.5 HSV Expressing Cytosine Deaminase|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.976  0.604
2003 Shah AC, Benos D, Gillespie GY, Markert JM. Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas. Journal of Neuro-Oncology. 65: 203-26. PMID 14682372 DOI: 10.1023/B:Neon.0000003651.97832.6C  0.384
2003 Tsai JC, Teng LJ, Chen CT, Hong TM, Goldman CK, Gillespie GY. Protein kinase C mediates induced secretion of vascular endothelial growth factor by human glioma cells. Biochemical and Biophysical Research Communications. 309: 952-60. PMID 13679066 DOI: 10.1016/J.Bbrc.2003.08.106  0.318
2003 Xia J, Zhou ZH, Bubien JK, Fuller CM, Markert JM, Mapstone TB, Gillespie GY, Benos DJ. Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter. Gene. 313: 91-101. PMID 12957380 DOI: 10.1016/S0378-1119(03)00633-4  0.342
2003 Safavy A, Bonner JA, Waksal HW, Buchsbaum DJ, Gillespie GY, Khazaeli MB, Arani R, Chen DT, Carpenter M, Raisch KP. Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug delivery. Bioconjugate Chemistry. 14: 302-10. PMID 12643740 DOI: 10.1021/Bc020033Z  0.557
2003 Berdiev BK, Xia J, McLean LA, Markert JM, Gillespie GY, Mapstone TB, Naren AP, Jovov B, Bubien JK, Ji HL, Fuller CM, Kirk KL, Benos DJ. Acid-sensing ion channels in malignant gliomas. The Journal of Biological Chemistry. 278: 15023-34. PMID 12584187 DOI: 10.1074/Jbc.M300991200  0.382
2002 Blanquicett C, Gillespie GY, Nabors LB, Miller CR, Bharara S, Buchsbaum DJ, Diasio RB, Johnson MR. Induction of thymidine phosphorylase in both irradiated and shielded, contralateral human U87MG glioma xenografts: implications for a dual modality treatment using capecitabine and irradiation. Molecular Cancer Therapeutics. 1: 1139-45. PMID 12481438  0.55
2002 Berdiev BK, Xia J, Jovov B, Markert JM, Mapstone TB, Gillespie GY, Fuller CM, Bubien JK, Benos DJ. Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function. The Journal of Biological Chemistry. 277: 45734-40. PMID 12244121 DOI: 10.1074/Jbc.M208995200  0.346
2002 Kaliberov SA, Buchsbaum DJ, Gillespie GY, Curiel DT, Arafat WO, Carpenter M, Stackhouse MA. Adenovirus-mediated transfer of BAX driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 190-8. PMID 12161185 DOI: 10.1006/Mthe.2002.0648  0.614
2002 Miller CR, Williams CR, Buchsbaum DJ, Gillespie GY. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Research. 62: 773-80. PMID 11830532  0.604
2001 Debinski W, Slagle-Webb B, Achen MG, Stacker SA, Tulchinsky E, Gillespie GY, Gibo DM. VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme. Molecular Medicine (Cambridge, Mass.). 7: 598-608. PMID 11778649 DOI: 10.1007/Bf03401866  0.355
2001 Ansardi DC, Porter DC, Jackson CA, Gillespie GY, Morrow CD. RNA replicons derived from poliovirus are directly oncolytic for human tumor cells of diverse origins. Cancer Research. 61: 8470-9. PMID 11731430  0.364
2001 Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA. Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences. Archives of Biochemistry and Biophysics. 394: 167-72. PMID 11594730 DOI: 10.1006/Abbi.2001.2540  0.351
2001 Markert JM, Fuller CM, Gillespie GY, Bubien JK, McLean LA, Hong RL, Lee K, Gullans SR, Mapstone TB, Benos DJ. Differential gene expression profiling in human brain tumors. Physiological Genomics. 5: 21-33. PMID 11161003 DOI: 10.1152/Physiolgenomics.2001.5.1.21  0.38
2000 Chatterjee S, Matsumura A, Schradermeier J, Gillespie GY. Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents. Journal of Neuro-Oncology. 46: 135-44. PMID 10894366 DOI: 10.1023/A:1006444300504  0.417
2000 Parker JN, Gillespie GY, Love CE, Randall S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 97: 2208-13. PMID 10681459 DOI: 10.1073/pnas.040557897  0.311
2000 Markert JM, Gillespie GY, Weichselbaum RR, Roizman B, Whitley RJ. Genetically engineered HSV in the treatment of glioma: a review. Reviews in Medical Virology. 10: 17-30. PMID 10654002 DOI: 10.1002/(Sici)1099-1654(200001/02)10:1<17::Aid-Rmv258>3.0.Co;2-G  0.3
1999 Secrist JA, Parker WB, Allan PW, Bennett LL, Waud WR, Truss JW, Fowler AT, Montgomery JA, Ealick SE, Wells AH, Gillespie GY, Gadi VK, Sorscher EJ. Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase. Nucleosides & Nucleotides. 18: 745-57. PMID 10432677 DOI: 10.1080/15257779908041562  0.308
1999 Bubien JK, Keeton DA, Fuller CM, Gillespie GY, Reddy AT, Mapstone TB, Benos DJ. Malignant human gliomas express an amiloride-sensitive Na+ conductance American Journal of Physiology - Cell Physiology. 276. PMID 10362604 DOI: 10.1152/Ajpcell.1999.276.6.C1405  0.414
1998 Miller CR, Buchsbaum DJ, Reynolds PN, Douglas JT, Gillespie GY, Mayo MS, Raben D, Curiel DT. Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer. Cancer Research. 58: 5738-48. PMID 9865732  0.61
1998 Goldman CK, Kendall RL, Cabrera G, Soroceanu L, Heike Y, Gillespie GY, Siegal GP, Mao X, Bett AJ, Huckle WR, Thomas KA, Curiel DT. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proceedings of the National Academy of Sciences of the United States of America. 95: 8795-800. PMID 9671758 DOI: 10.1073/Pnas.95.15.8795  0.47
1998 Parker WB, Allan PW, Shaddix SC, Rose LM, Speegle HF, Gillespie GY, Bennett LL. Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells Biochemical Pharmacology. 55: 1673-1681. PMID 9634004 DOI: 10.1016/S0006-2952(98)00034-3  0.331
1998 Wang-Johanning F, Gillespie GY, Grim J, Rancourt C, Alvarez RD, Siegal GP, Curiel DT. Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects. Cancer Research. 58: 1893-900. PMID 9581830  0.331
1997 Parker WB, King SA, Allan PW, Bennett LL, Secrist JA, Montgomery JA, Gilbert KS, Waud WR, Wells AH, Gillespie GY, Sorscher EJ. In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase. Human Gene Therapy. 8: 1637-44. PMID 9322865 DOI: 10.1089/Hum.1997.8.14-1637  0.4
1997 Goldman CK, Bharara S, Palmer CA, Vitek J, Tsai JC, Weiss HL, Gillespie GY. Brain edema in meningiomas is associated with increased vascular endothelial growth factor expression. Neurosurgery. 40: 1269-77. PMID 9179901 DOI: 10.1097/00006123-199706000-00029  0.305
1997 Goldman CK, Soroceanu L, Smith N, Gillespie GY, Shaw W, Burgess S, Bilbao G, Curiel DT. In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer. Nature Biotechnology. 15: 462-6. PMID 9131627 DOI: 10.1038/nbt0597-462  0.384
1996 Andreansky SS, He B, Gillespie GY, Soroceanu L, Markert J, Chou J, Roizman B, Whitley RJ. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 93: 11313-8. PMID 8876132 DOI: 10.1073/Pnas.93.21.11313  0.315
1996 Raben D, Buchsbaum DJ, Khazaeli MB, Rosenfeld ME, Gillespie GY, Grizzle WE, Liu T, Curiel DT. Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene Gene Therapy. 3: 567-580. PMID 8818643  0.631
1995 Chambers R, Gillespie GY, Soroceanu L, Andreansky S, Chatterjee S, Chou J, Roizman B, Whitley RJ. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 92: 1411-5. PMID 7877992 DOI: 10.1073/pnas.92.5.1411  0.311
1995 Tsai JC, Goldman CK, Gillespie GY. Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF. Journal of Neurosurgery. 82: 864-73. PMID 7714613 DOI: 10.3171/Jns.1995.82.5.0864  0.34
1995 Raben D, Buchsbaum DJ, Khazaeli MB, Rosenfeld ME, Gillespie GY, Curiel DT. ADENOVIRAL-MEDIATED TRANSDUCTION OF GENES CODING FOR SURFACE RECEPTORS TO IMPROVE RADIOLIGAND TUMOR LOCALIZATION Journal of Immunotherapy. 18: 130. DOI: 10.1097/00002371-199508000-00019  0.391
1994 Lyon E, Gillespie GY. Monoclonal antibodies to glioma-derived growth factor(s). Hybridoma. 13: 15-20. PMID 8200654 DOI: 10.1089/Hyb.1994.13.15  0.304
1994 Lyon E, Gillespie GY. Partial characterization of glioma-derived growth factor 2: a novel mitogenic activity from human cell line D-54 MG. Journal of Neuro-Oncology. 17: 99-109. PMID 8145064 DOI: 10.1007/Bf01050212  0.323
1990 Mahaley MS, Gillespie GY, Hammett R. Computerized tomography brain scan tumor volume determinations. Sensitivity as an objective criterion of response to therapy. Journal of Neurosurgery. 72: 872-8. PMID 2187058 DOI: 10.3171/Jns.1990.72.6.0872  0.34
1990 Bethea JR, Gillespie GY, Chung IY, Benveniste EN. Tumor necrosis factor production and receptor expression by a human malignant glioma cell line, D54-MG. Journal of Neuroimmunology. 30: 1-13. PMID 2172302 DOI: 10.1016/0165-5728(90)90047-Q  0.304
1987 el-Hennawi Y, Gillespie GY, Mahaley MS, Bigner DD. Treatment of autochthonous rat brain tumors with steroid plus heparin: a brief report. Journal of Neuro-Oncology. 5: 161-2. PMID 3668611 DOI: 10.1007/Bf02571304  0.343
1986 Powers SK, Pribil S, Gillespie GY, Watkins PJ. Laser photochemotherapy of rhodamine-123 sensitized human glioma cells in vitro. Journal of Neurosurgery. 64: 918-23. PMID 3701443 DOI: 10.3171/Jns.1986.64.6.0918  0.334
1984 Buessow SC, Gillespie GY, Mahaley MS. Tumoricidal activity of an acute promyelocytic leukemia cell line (HL-60) is augmented by human interferon alpha. Leukemia Research. 8: 801-11. PMID 6593510 DOI: 10.1016/0145-2126(84)90101-2  0.383
1982 Wharton W, Gillespie GY, Russell SW, Pledger WJ. Mitogenic activity elaborated by macrophage‐like cell lines acts as competence factor(s) for BALB/c 3T3 cells Journal of Cellular Physiology. 110: 93-100. PMID 7068768 DOI: 10.1002/Jcp.1041100115  0.303
1980 Russell SW, Gillespie GY, Pace JL. Evidence for mononuclear phagocytes in solid neoplasms and appraisal of their nonspecific cytotoxic capabilities. Contemporary Topics in Immunobiology. 10: 143-66. PMID 7408488 DOI: 10.1007/978-1-4684-3677-8_6  0.324
1978 Gillespie GY, Barth RF. Lymphocyte mediated reactivity against malignant melanoma detected by a microcytotoxicity assay employing technetium-99m labeled target cells. Cancer. 41: 2174-82. PMID 350374 DOI: 10.1002/1097-0142(197806)41:6<2174::Aid-Cncr2820410616>3.0.Co;2-M  0.38
1978 Gillespie GY, Jensen FC, Russell SW. B-tropic oncornavirus production by BALB/c methylcholanthrene-induced sarcoma cells. International Journal of Cancer. 21: 234-8. PMID 203550 DOI: 10.1002/Ijc.2910210216  0.321
1977 Hansen CB, Gillespie GY, Russell SW. Isolation of T-lymphocytes from disaggregated tumors, with high purity and good percentage recovery. Journal of the National Cancer Institute. 59: 273-5. PMID 195071 DOI: 10.1093/Jnci/59.1.273  0.375
1976 Wood GW, Gillespie GY. Studies on the role of macrophages in regulation of growth and metastasis of murine chemically induced fibrosarcomas. International Journal of Cancer. 16: 1022-9. PMID 1201871 DOI: 10.1002/ijc.2910160616  0.323
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