| Year |
Citation |
Score |
| 2023 |
Li E, Kampmann M. Toward a CRISPR understanding of gene function in human brain development. Cell Stem Cell. 30: 1561-1562. PMID 38065064 DOI: 10.1016/j.stem.2023.11.005 |
0.637 |
|
| 2023 |
Li E, Benitez C, Boggess SC, Koontz M, Rose IVL, Draeger N, Teter OM, Samelson AJ, Ullian EM, Kampmann M. CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. Biorxiv : the Preprint Server For Biology. PMID 37163077 DOI: 10.1101/2023.04.26.538498 |
0.666 |
|
| 2022 |
Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, ... Kampmann M, et al. Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. Elife. 11. PMID 36576240 DOI: 10.7554/eLife.81856 |
0.545 |
|
| 2022 |
Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, ... ... Kampmann M, et al. A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell. 29: 1685-1702.e22. PMID 36459969 DOI: 10.1016/j.stem.2022.11.004 |
0.653 |
|
| 2022 |
Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, ... ... Kampmann M, et al. CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states. Nature Neuroscience. PMID 36303069 DOI: 10.1038/s41593-022-01180-9 |
0.654 |
|
| 2022 |
Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, ... ... Kampmann M, et al. A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states. Nature Neuroscience. PMID 35953545 DOI: 10.1038/s41593-022-01131-4 |
0.318 |
|
| 2022 |
Samelson AJ, Tran QD, Robinot R, Carrau L, Rezelj VV, Kain AM, Chen M, Ramadoss GN, Guo X, Lim SA, Lui I, Nuñez JK, Rockwood SJ, Wang J, Liu N, ... ... Kampmann M, et al. BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nature Cell Biology. 24: 24-34. PMID 35027731 DOI: 10.1038/s41556-021-00821-8 |
0.78 |
|
| 2021 |
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Elife. 10. PMID 34034859 DOI: 10.7554/eLife.67624 |
0.464 |
|
| 2021 |
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, ... Kampmann M, et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. PMID 33838111 DOI: 10.1016/j.cell.2021.03.025 |
0.777 |
|
| 2021 |
Tian R, Samelson AJ, Rezelj VV, Chen M, Ramadoss GN, Guo X, Kain AM, Tran QD, Lim SA, Lui I, Nunez J, Rockwood SJ, Liu N, Carlson-Stevermer J, Oki J, ... ... Kampmann M, et al. BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2. Biorxiv : the Preprint Server For Biology. PMID 33501440 DOI: 10.1101/2021.01.19.427194 |
0.776 |
|
| 2021 |
Leng K, Li E, Eser R, Piergies A, Sit R, Tan M, Neff N, Li SH, Rodriguez RD, Suemoto CK, Leite REP, Ehrenberg AJ, Pasqualucci CA, Seeley WW, Spina S, ... ... Kampmann M, et al. Molecular characterization of selectively vulnerable neurons in Alzheimer's disease. Nature Neuroscience. PMID 33432193 DOI: 10.1038/s41593-020-00764-7 |
0.61 |
|
| 2020 |
Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Defining the ATPome reveals cross-optimization of metabolic pathways. Nature Communications. 11: 4319. PMID 32859923 DOI: 10.1038/S41467-020-18084-6 |
0.303 |
|
| 2020 |
Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, ... ... Kampmann M, et al. Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. Acs Chemical Biology. PMID 32786289 DOI: 10.1021/Acschembio.0C00339 |
0.31 |
|
| 2020 |
Kampmann M. CRISPR-based functional genomics for neurological disease. Nature Reviews. Neurology. PMID 32641861 DOI: 10.1038/S41582-020-0373-Z |
0.413 |
|
| 2020 |
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 79: 191-198.e3. PMID 32619469 DOI: 10.1016/J.Molcel.2020.06.008 |
0.554 |
|
| 2020 |
Ramkumar P, Abarientos AB, Tian R, Seyler M, Leong JT, Chen M, Choudhry P, Hechler T, Shah N, Wong SW, Martin TG, Wolf JL, Roybal KT, Pahl A, Taunton J, ... ... Kampmann M, et al. CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma. Blood Advances. 4: 2899-2911. PMID 32589729 DOI: 10.1182/Bloodadvances.2019001346 |
0.401 |
|
| 2020 |
Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature. PMID 32132707 DOI: 10.1038/S41586-020-2078-2 |
0.324 |
|
| 2020 |
Oh E, Mark KG, Mocciaro A, Watson ER, Prabu JR, Cha DD, Kampmann M, Gamarra N, Zhou CY, Rape M. Gene expression and cell identity controlled by anaphase-promoting complex. Nature. PMID 32076268 DOI: 10.1038/S41586-020-2034-1 |
0.385 |
|
| 2019 |
Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M. Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation. The Journal of Biological Chemistry. PMID 31578281 DOI: 10.1074/Jbc.Ra119.009432 |
0.332 |
|
| 2019 |
Uckeley ZM, Moeller R, Kühn LI, Nilsson E, Robens C, Lasswitz L, Lindqvist R, Lenman A, Passos V, Voss Y, Sommerauer C, Kampmann M, Goffinet C, Meissner F, Överby AK, et al. Quantitative proteomics of Uukuniemi virus - host cell interactions reveals GBF1 as proviral host factor for phleboviruses. Molecular & Cellular Proteomics : McP. PMID 31570497 DOI: 10.1074/Mcp.Ra119.001631 |
0.315 |
|
| 2019 |
Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M. CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons. Neuron. PMID 31422865 DOI: 10.1016/J.Neuron.2019.07.014 |
0.407 |
|
| 2019 |
Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 8. PMID 31149896 DOI: 10.7554/Elife.46595 |
0.628 |
|
| 2019 |
Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/J.Molcel.2019.01.036 |
0.567 |
|
| 2019 |
Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, ... ... Kampmann M, et al. Heterochromatin anomalies and double-stranded RNA accumulation underlie poly(PR) toxicity. Science (New York, N.Y.). 363. PMID 30765536 DOI: 10.1126/Science.Aav2606 |
0.324 |
|
| 2019 |
Poulard C, Kim HN, Fang M, Kruth K, Gagnieux C, Gerke DS, Bhojwani D, Kim YM, Kampmann M, Stallcup MR, Pufall MA. Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. PMID 30733284 DOI: 10.1073/Pnas.1816254116 |
0.37 |
|
| 2019 |
Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Author response: Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether Elife. DOI: 10.7554/Elife.46595.022 |
0.563 |
|
| 2018 |
Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K. A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. Plos Biology. 16: e2004624. PMID 30148842 DOI: 10.1371/Journal.Pbio.2004624 |
0.382 |
|
| 2018 |
Ramkumar P, Kampmann M. CRISPR-based genetic interaction maps inform therapeutic strategies in cancer. Translational Cancer Research. 7: S61-S67. PMID 30148072 DOI: 10.21037/Tcr.2018.01.02 |
0.367 |
|
| 2018 |
Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, ... ... Kampmann M, et al. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 174: 505-520. PMID 30053424 DOI: 10.1016/J.Cell.2018.06.016 |
0.349 |
|
| 2018 |
Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Mapping the Genetic Landscape of Human Cells. Cell. PMID 30033366 DOI: 10.1016/J.Cell.2018.06.010 |
0.545 |
|
| 2018 |
Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS. Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). Scientific Reports. 8: 6382. PMID 29686391 DOI: 10.1038/S41598-018-24904-Z |
0.326 |
|
| 2018 |
Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nature Biotechnology. PMID 29334369 DOI: 10.1038/Nbt.4062 |
0.391 |
|
| 2018 |
Kampmann M. CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. Acs Chemical Biology. 13: 406-416. PMID 29035510 DOI: 10.1021/Acschembio.7B00657 |
0.457 |
|
| 2018 |
Ramkumar P, Leong J, Seyler M, Georgoulis SJ, Hyrenius Wittsten A, Choudhry P, Roybal K, Wiita AP, Kampmann M. Identifying Factors in Multiple Myeloma Controlling Response to B-Cell Maturation Antigen (BCMA)-Targeted Immunotherapy Using CRISPR-Based Functional Genomics Blood. 132: 1926-1926. DOI: 10.1182/Blood-2018-99-115368 |
0.451 |
|
| 2017 |
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 68: 210-223.e6. PMID 28985505 DOI: 10.1016/J.Molcel.2017.09.012 |
0.573 |
|
| 2017 |
Nagy T, Kampmann M. CRISPulator: a discrete simulation tool for pooled genetic screens. Bmc Bioinformatics. 18: 347. PMID 28732459 DOI: 10.1186/S12859-017-1759-9 |
0.314 |
|
| 2017 |
Kampmann M. Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. Chemical Communications (Cambridge, England). 53: 7162-7167. PMID 28487920 DOI: 10.1039/C7Cc02349A |
0.391 |
|
| 2017 |
Kampmann M. A CRISPR Approach to Neurodegenerative Diseases. Trends in Molecular Medicine. 23: 483-485. PMID 28478951 DOI: 10.1016/J.Molmed.2017.04.003 |
0.406 |
|
| 2017 |
Kruth K, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. PMID 28424165 DOI: 10.1182/Blood-2017-02-766204 |
0.552 |
|
| 2017 |
Ramkumar P, Tawney J, Acosta-Alvear D, Kampmann M. Abstract A30: Identifying microenvironment-dependent vulnerabilities in multiple myeloma using CRISPRi Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A30 |
0.434 |
|
| 2016 |
Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/J.Chom.2016.11.001 |
0.473 |
|
| 2016 |
Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 5. PMID 27661255 DOI: 10.7554/Elife.19760 |
0.57 |
|
| 2016 |
Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Nature Chemical Biology. PMID 27018887 DOI: 10.1038/Nchembio.2050 |
0.387 |
|
| 2016 |
Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Author response: Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation Elife. DOI: 10.7554/Elife.19760.031 |
0.512 |
|
| 2015 |
Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, et al. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 28: 653-65. PMID 26555175 DOI: 10.1016/J.Ccell.2015.10.002 |
0.554 |
|
| 2015 |
Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 4. PMID 26327694 DOI: 10.7554/Elife.08153 |
0.565 |
|
| 2015 |
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Next-generation libraries for robust RNA interference-based genome-wide screens. Proceedings of the National Academy of Sciences of the United States of America. 112: E3384-91. PMID 26080438 DOI: 10.1073/Pnas.1508821112 |
0.568 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/Elife.07314 |
0.635 |
|
| 2015 |
Kampmann M, Bassik MC, Weissman JS. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 10: 643. PMID 25811902 DOI: 10.1038/Nprot0415-644D |
0.536 |
|
| 2015 |
Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Validation of the hsp70-bag3 protein-protein interaction as a potential therapeutic target in cancer. Molecular Cancer Therapeutics. 14: 642-8. PMID 25564440 DOI: 10.1158/1535-7163.Mct-14-0650 |
0.629 |
|
| 2015 |
Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Author response: Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits Elife. DOI: 10.7554/Elife.08153.019 |
0.572 |
|
| 2015 |
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Author response: Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response Elife. DOI: 10.7554/Elife.07314.017 |
0.561 |
|
| 2015 |
Acosta-Alvear D, Kampmann M, Cho MY, Wild T, Choudhary C, Shuman MA, Weissman JS, Walter P. Abstract A43: Opposing roles of the 19S regulatory- and 20S core-proteasomal subunits in controlling sensitivity of multiple myeloma cells to proteasome inhibition. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A43 |
0.661 |
|
| 2015 |
Gilbert LA, Tanenbaum ME, Horlbeck MA, Adamson B, Villalta JE, Vale RD, Kampmann M, Weissman JS. Abstract PR05: Using genome-scale CRISPR-mediated loss-of-function and gain-of-function screens to analyze gene-drug interactions in cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr05 |
0.582 |
|
| 2015 |
Acosta-Alvear D, Kampmann M, Cho MY, Aftab BT, Li X, Gestwicki JE, Shuman MA, Weissman JS, Walter P. Abstract A2-57: Identification of genetic vulnerabilities within the proteostasis network of multiple myeloma Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-57 |
0.671 |
|
| 2015 |
Kampmann M, Acosta-Alvear D, Gilbert LA, Horlbeck MA, Cho MY, Adamson B, Villalta J, Chen Y, Walter P, Weissman JS. Abstract A2-56: Cancer-specific synthetic lethality and network rewiring elucidated by genetic interaction maps and CRISPR-based gain- and loss-of-function screens Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-56 |
0.683 |
|
| 2015 |
Cho MY, Acosta-Alvear D, Kampmann M, Wild T, Choudhary CR, Weissman JS, Walter P. Abstract A2-12: Opposing roles of the 19S regulatory and 20S core proteasomal subunits in controlling sensitivity to proteasome inhibitors Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-12 |
0.673 |
|
| 2014 |
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 159: 647-61. PMID 25307932 DOI: 10.1016/J.Cell.2014.09.029 |
0.598 |
|
| 2014 |
Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA. Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs. Nucleic Acids Research. 42: 12169-76. PMID 25270879 DOI: 10.1093/Nar/Gku854 |
0.322 |
|
| 2014 |
Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/Nchembio.1639 |
0.535 |
|
| 2014 |
Kampmann M, Bassik MC, Weissman JS. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 9: 1825-47. PMID 24992097 DOI: 10.1038/Nprot.2014.103 |
0.571 |
|
| 2014 |
Aftab BT, Anderson DJ, Le Moigne R, Djakovic S, Dhimolea E, Murnane M, King E, Rice J, Wong S, Kumar B, Valle E, Menon M, Kiss von Soly S, Wang J, Yao B, ... ... Kampmann M, et al. Pre-Clinical Activity of the Novel, First-in-Class p97 Inhibitor, CB-5083, in Multiple Myeloma Blood. 124: 4701-4701. DOI: 10.1182/Blood.V124.21.4701.4701 |
0.396 |
|
| 2014 |
Julien O, Kampmann M, Bassik MC, Venditto VJ, Zorn JA, Rheingold AL, Weissman JS, Wells JA. Unraveling the Mechanism of Cell Death Induced by Chemical and Protein Fibrils Biophysical Journal. 106: 40a. DOI: 10.1016/J.Bpj.2013.11.297 |
0.592 |
|
| 2013 |
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chemistry & Biology. 20: 1352-63. PMID 24183972 DOI: 10.1016/J.Chembiol.2013.09.014 |
0.564 |
|
| 2013 |
Kampmann M, Bassik MC, Weissman JS. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E2317-26. PMID 23739767 DOI: 10.1073/Pnas.1307002110 |
0.6 |
|
| 2013 |
Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/J.Cell.2013.01.030 |
0.56 |
|
| 2013 |
Atkinson CE, Mattheyses AL, Kampmann M, Simon SM. Conserved spatial organization of FG domains in the nuclear pore complex. Biophysical Journal. 104: 37-50. PMID 23332057 DOI: 10.1016/J.Bpj.2012.11.3823 |
0.548 |
|
| 2013 |
Wei MC, Matheny CJ, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley D, Rau RE, Brown P, McManus MT, Weissman JS, Cleary ML. Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens Blood. 122: 171-171. DOI: 10.1182/Blood.V122.21.171.171 |
0.608 |
|
| 2013 |
Kampmann M, Acosta-Alvear D, Cho M, Chen Y, Li X, Gilbert L, Aftab BT, Gestwicki J, Walter P, Weissman JS. Abstract PR07: Systematic genetic interaction maps reveal rewiring of the stress response network and resulting vulnerabilities in leukemia and multiple myeloma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Pr07 |
0.679 |
|
| 2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Cho MY, Aftab BT, Li X, Gestwicki JE, Shuman MA, Weissman JS, Walter P. Abstract C01: Systematic blueprinting of genetic vulnerabilities using ultra-complex shRNA libraries identifies genes synergizing with proteasome inhibition or blockade of IRE1 in multiple myeloma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C01 |
0.686 |
|
| 2013 |
Kampmann M, Acosta-Alvear D, Bassik MC, Chen Y, Walter P, Weissman JS. Abstract PR06: Systematic genetic interaction maps reveal synthetic-lethal vulnerabilities in leukemia and multiple myeloma Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Pr06 |
0.675 |
|
| 2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Shuman MA, Weissman JS, Walter P. Abstract A08: Systematic identification of genetic vulnerabilities synergizing with proteasome and IRE1 inhibition in multiple myeloma cells using ultra-complex shRNA libraries Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A08 |
0.682 |
|
| 2012 |
Atkinson CE, Mattheyses AL, Kampmann M, Simon SM. Effect of FG Motifs on Ordering Proteins within the Nuclear Pore Complex Biophysical Journal. 102: 525a. DOI: 10.1016/J.Bpj.2011.11.2870 |
0.551 |
|
| 2011 |
Bassik MC, Kampmann M. Knocking out the door to tunicamycin entry Proceedings of the National Academy of Sciences of the United States of America. 108: 11731-11732. PMID 21734150 DOI: 10.1073/Pnas.1109035108 |
0.362 |
|
| 2011 |
Kampmann M, Atkinson CE, Mattheyses AL, Simon SM. Mapping the orientation of nuclear pore proteins in living cells with polarized fluorescence microscopy. Nature Structural & Molecular Biology. 18: 643-9. PMID 21499242 DOI: 10.1038/Nsmb.2056 |
0.568 |
|
| 2011 |
Atkinson CE, Kampmann M, Mattheyses AL, Simon SM. The Structure of the Nuclear Pore Complex Studied by Fluorescence Anisotropy Biophysical Journal. 100: 140a. DOI: 10.1016/J.Bpj.2010.12.967 |
0.556 |
|
| 2011 |
Mattheyses AL, Kampmann M, Atkinson CE, Simon SM. Protein Domain Organization in the Nuclear Pore Complex Studied by Fluorescence Anisotropy Biophysical Journal. 100: 139a-140a. DOI: 10.1016/J.Bpj.2010.12.966 |
0.544 |
|
| 2010 |
Mattheyses AL, Kampmann M, Atkinson CE, Simon SM. Fluorescence anisotropy reveals order and disorder of protein domains in the nuclear pore complex. Biophysical Journal. 99: 1706-17. PMID 20858414 DOI: 10.1016/J.Bpj.2010.06.075 |
0.539 |
|
| 2009 |
Kampmann M, Blobel G. Biochemistry. Nascent proteins caught in the act. Science (New York, N.Y.). 326: 1352-3. PMID 19965743 DOI: 10.1126/Science.1183690 |
0.481 |
|
| 2009 |
Nagy V, Hsia KC, Debler EW, Kampmann M, Davenport AM, Blobel G, Hoelz A. Structure of a trimeric nucleoporin complex reveals alternate oligomerization states. Proceedings of the National Academy of Sciences of the United States of America. 106: 17693-8. PMID 19805193 DOI: 10.1073/Pnas.0909373106 |
0.712 |
|
| 2009 |
Kampmann M, Blobel G. Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex. Nature Structural & Molecular Biology. 16: 782-8. PMID 19503077 DOI: 10.1038/Nsmb.1618 |
0.484 |
|
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