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Jon E. Paczkowski - Publications

Affiliations: 
Princeton University, Princeton, NJ 
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rasal TA, Mallery CP, Brockley MW, Brown LC, Paczkowski JE, van Kessel JC. Ligand binding determines proteolytic stability of LuxR/HapR quorum sensing transcription factors. Biorxiv : the Preprint Server For Biology. PMID 38405947 DOI: 10.1101/2024.02.15.580527  0.372
2023 Keegan NR, Colón Torres NJ, Stringer AM, Prager LI, Brockley MW, McManaman CL, Wade JT, Paczkowski JE. Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine lactone and PqsE. Plos Genetics. 19: e1010900. PMID 38064526 DOI: 10.1371/journal.pgen.1010900  0.306
2022 Feathers JR, Richael EK, Simanek KA, Fromme JC, Paczkowski JE. Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation. Structure (London, England : 1993). PMID 36379213 DOI: 10.1016/j.str.2022.10.008  0.325
2022 Simanek KA, Paczkowski JE. Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance. Microorganisms. 10. PMID 35744765 DOI: 10.3390/microorganisms10061247  0.323
2022 Simanek KA, Taylor IR, Richael EK, Lasek-Nesselquist E, Bassler BL, Paczkowski JE. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiology Spectrum. e0210821. PMID 35019777 DOI: 10.1128/spectrum.02108-21  0.56
2021 Taylor IR, Paczkowski JE, Jeffrey PD, Henke BR, Smith CD, Bassler BL. Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. Acs Chemical Biology. PMID 33793200 DOI: 10.1021/acschembio.1c00049  0.566
2020 Huang X, Duddy OP, Silpe JE, Paczkowski JE, Cong J, Henke BR, Bassler BL. Mechanism underlying autoinducer recognition in the  DPO-VqmA quorum-sensing pathway. The Journal of Biological Chemistry. PMID 31964715 DOI: 10.1074/Jbc.Ra119.012104  0.632
2019 McCready AR, Paczkowski JE, Cong JP, Bassler BL. An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation. Plos Pathogens. 15: e1007820. PMID 31194839 DOI: 10.1371/Journal.Ppat.1007820  0.614
2019 Paczkowski JE, McCready AR, Cong JP, Li Z, Jeffrey PD, Smith CD, Henke BR, Hughson FM, Bassler BL. An autoinducer analog reveals an alternative mode of ligand binding for the LasR quorum-sensing receptor. Acs Chemical Biology. PMID 30763066 DOI: 10.1021/Acschembio.8B00971  0.604
2019 McCready AR, Paczkowski JE, Henke BR, Bassler BL. Structural determinants driving homoserine lactone ligand selection in the LasR quorum-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America. 116: 245-254. PMID 30559209 DOI: 10.1073/pnas.1817239116  0.588
2019 McCready AR, Paczkowski JE, Henke BR, Bassler BL. Structural determinants driving homoserine lactone ligand selection in thePseudomonas aeruginosaLasR quorum-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America. 116: 245-254. DOI: 10.2210/Pdb6Mvm/Pdb  0.615
2019 Paczkowski J. Structural Basis Underlying Autoinducer Activation of the Vibrio cholerae VqmA Quorum-Sensing Receptor Biophysical Journal. 116: 184a. DOI: 10.1016/J.Bpj.2018.11.1021  0.327
2017 Paczkowski JE, Mukherjee S, McCready AR, Cong JP, Aquino CJ, Kim H, Henke BR, Smith CD, Bassler BL. Flavonoids suppress Pseudomonas aeruginosa virulence through allosteric inhibition of quorum-sensing receptors. The Journal of Biological Chemistry. PMID 28119451 DOI: 10.1074/Jbc.M116.770552  0.61
2016 Høyland-Kroghsbo NM, Paczkowski J, Mukherjee S, Broniewski J, Westra E, Bondy-Denomy J, Bassler BL. Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system. Proceedings of the National Academy of Sciences of the United States of America. PMID 27849583 DOI: 10.1073/Pnas.1617415113  0.622
2016 Paczkowski JE, Fromme JC. Analysis of Arf1 GTPase-Dependent Membrane Binding and Remodeling Using the Exomer Secretory Vesicle Cargo Adaptor. Methods in Molecular Biology (Clifton, N.J.). 1496: 41-53. PMID 27632000 DOI: 10.1007/978-1-4939-6463-5_4  0.666
2015 Paczkowski JE, Richardson BC, Fromme JC. Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis. Trends in Cell Biology. 25: 408-16. PMID 25795254 DOI: 10.1016/J.Tcb.2015.02.005  0.691
2014 Paczkowski JE, Fromme JC. Structural basis for membrane binding and remodeling by the exomer secretory vesicle cargo adaptor. Developmental Cell. 30: 610-24. PMID 25203211 DOI: 10.1016/J.Devcel.2014.07.014  0.676
2012 Paczkowski JE, Richardson BC, Strassner AM, Fromme JC. The exomer cargo adaptor structure reveals a novel GTPase-binding domain. The Embo Journal. 31: 4191-203. PMID 23000721 DOI: 10.1038/Emboj.2012.268  0.678
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