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Paul G. Royall, PhD - Publications

Affiliations: 
1994 The Chemical Laboratory University of Kent at Canterbury 
 1995-2007 School of Pharmacy University of London, London, England, United Kingdom 
 2007- Institute of Pharmaceutical Science King's College London, London, UK 
Area:
Amorphous materials, lactose, freeze dried formulations
Website:
https://scholar.google.com/citations?hl=en&user=rJnzGwkAAAAJ&view_op=list_works&sortby=pubdate
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51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Alzoubi T, Martin GP, Royall PG. A study of solid-state epimerisation within lactose powders and implications for milk derived ingredients stored in simulated tropical environmental zones. Food Chemistry. 402: 134206. PMID 36162173 DOI: 10.1016/j.foodchem.2022.134206  0.764
2022 Alsalhi MS, Royall PG, Chan KLA. Mechanistic study of the solubilization effect of basic amino acids on a poorly water-soluble drug. Rsc Advances. 12: 19040-19053. PMID 35865577 DOI: 10.1039/d2ra02870k  0.621
2021 Pollard C, Hudson M, McDonnell JM, Royall PG, Wolff K. Development of a point-of-care test for the detection of MDMA in latent fingerprints using surface plasmon resonance and lateral flow technology. Drug Testing and Analysis. PMID 34766468 DOI: 10.1002/dta.3196  0.538
2021 Malallah O, Rashid Z, Li CL, Alqurshi A, Alhanan MA, Forbes B, Royall PG. Digital Image Disintegration Analysis: a Novel Quality Control Method for Fast Disintegrating Tablets. Aaps Pharmscitech. 22: 219. PMID 34401966 DOI: 10.1208/s12249-021-02080-0  0.766
2021 Alzoubi T, Martin GP, Barlow DJ, Royall PG. Stability of α-lactose monohydrate: The discovery of dehydration triggered solid-state epimerization. International Journal of Pharmaceutics. 120715. PMID 34048927 DOI: 10.1016/j.ijpharm.2021.120715  0.781
2021 Abdul-Jabbar S, Martin GP, Martini LG, Lawrence J, Royall PG. Polyelectrolyte Multi-Layered Griseofulvin Nanoparticles: Conventional versus Continuous Layer-by-Layer Fabrication. Journal of Nanoscience and Nanotechnology. 21: 5611-5621. PMID 33980370 DOI: 10.1166/jnn.2021.19453  0.763
2021 Abdul-Jabbar S, Wong DW, Martin GP, Woodhead B, Royall PG. Repurposing Melt Degradation for the Evaluation of Mixed Amorphous-Crystalline Blends. Aaps Pharmscitech. 22: 105. PMID 33718988 DOI: 10.1208/s12249-021-01971-6  0.765
2020 Pollard C, Sievers C, Royall PG, Wolff K. Evaluation of Latent Fingerprints for Drug-Screening In A Social Care Setting. Journal of Analytical Toxicology. PMID 33263738 DOI: 10.1093/jat/bkaa183  0.523
2020 Sofian ZM, Benaouda F, Wang JT, Lu Y, Barlow DJ, Royall PG, Farag DB, Rahman KM, Al-Jamal KT, Forbes B, Jones SA. A Cyclodextrin-Stabilized Spermine-Tagged Drug Triplex that Targets Theophylline to the Lungs Selectively in Respiratory Emergency. Advanced Therapeutics. 2000153. PMID 33043128 DOI: 10.1002/adtp.202000153  0.759
2019 Malallah OS, Hammond B, Al-Adhami T, Buanz A, Alqurshi A, Carswell WD, Miraz Rahman K, Forbes B, Royall PG. Solid-state epimerisation and disproportionation of pilocarpine HCl: Why we need a 5-stage approach to validate melting point measurements for heat-sensitive drugs. International Journal of Pharmaceutics. 118869. PMID 31765787 DOI: 10.1016/J.Ijpharm.2019.118869  0.77
2019 Hanafy AF, Abdalla AM, Guda TK, Gabr KE, Royall PG, Alqurshi A. Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles. International Journal of Nanomedicine. 14: 3679-3689. PMID 31239660 DOI: 10.2147/Ijn.S195892  0.764
2018 Jamal Altamimi M, Wolff K, Nokhodchi A, Martin GP, Royall PG. Variability in the α and β anomer content of commercially available lactose. International Journal of Pharmaceutics. PMID 30395957 DOI: 10.1016/J.Ijpharm.2018.10.061  0.362
2018 Hassoun M, Royall PG, Parry M, Harvey RD, Forbes B. Design and development of a biorelevant simulated human lung fluid. Journal of Drug Delivery Science and Technology. 47: 485-491. PMID 30283501 DOI: 10.1016/J.Jddst.2018.08.006  0.774
2018 Jawad R, Elleman C, Martin GP, Royall PG. Crystallisation of freeze-dried sucrose in model mixtures that represent the amorphous sugar matrices present in confectionery. Food & Function. PMID 30027968 DOI: 10.1039/C8Fo00729B  0.793
2018 Terakosolphan W, Trick JL, Royall PG, Rogers SE, Lamberti O, Lorenz CD, Forbes B, Harvey RD. Glycerol solvates DPPC headgroups and localises in the interfacial regions of model pulmonary interfaces altering bilayer structure. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29738253 DOI: 10.1021/Acs.Langmuir.8B00866  0.313
2018 Malallah OS, Garcia CMA, Proctor GB, Forbes B, Royall PG. Buccal drug delivery technologies for patient-centred treatment of radiation-induced xerostomia (dry mouth). International Journal of Pharmaceutics. PMID 29425763 DOI: 10.1016/J.Ijpharm.2018.02.004  0.748
2017 Alqurshi A, Chan KLA, Royall PG. In-situ freeze-drying - forming amorphous solids directly within capsules: An investigation of dissolution enhancement for a poorly soluble drug. Scientific Reports. 7: 2910. PMID 28588206 DOI: 10.1038/S41598-017-02676-2  0.423
2017 Kumar A, Terakosolphan W, Hassoun M, Vandera KK, Novicky A, Harvey R, Royall PG, Bicer EM, Eriksson J, Edwards K, Valkenborg D, Nelissen I, Hassall D, Mudway IS, Forbes B. A Biocompatible Synthetic Lung Fluid Based on Human Respiratory Tract Lining Fluid Composition. Pharmaceutical Research. PMID 28560698 DOI: 10.1007/S11095-017-2169-4  0.736
2016 Strang J, McDonald R, Alqurshi A, Royall P, Taylor D, Forbes B. Naloxone without the needle - systematic review of candidate routes for non-injectable naloxone for opioid overdose reversal. Drug and Alcohol Dependence. PMID 26996745 DOI: 10.1016/J.Drugalcdep.2016.02.042  0.729
2016 Alqurshi A, Kumar Z, Mcdonald R, Strang J, Buanz A, Ahmed S, Allen E, Cameron P, Rickard JA, Sandhu V, Holt C, Stansfield R, Taylor D, Forbes B, Royall PG. Amorphous formulation and in vitro performance testing of instantly disintegrating buccal tablets for the emergency delivery of naloxone. Molecular Pharmaceutics. PMID 26977787 DOI: 10.1021/Acs.Molpharmaceut.6B00096  0.401
2014 Jawad R, Drake AF, Elleman C, Martin GP, Warren FJ, Perston BB, Ellis PR, Hassoun MA, Royall PG. Stability of sugar solutions: a novel study of the epimerization kinetics of lactose in water. Molecular Pharmaceutics. 11: 2224-38. PMID 24815988 DOI: 10.1021/Mp400509T  0.756
2014 Buttini F, Miozzi M, Balducci AG, Royall PG, Brambilla G, Colombo P, Bettini R, Forbes B. Differences in physical chemistry and dissolution rate of solid particle aerosols from solution pressurised inhalers. International Journal of Pharmaceutics. 465: 42-51. PMID 24491530 DOI: 10.1016/J.Ijpharm.2014.01.033  0.302
2013 Warren FJ, Perston BB, Royall PG, Butterworth PJ, Ellis PR. Infrared spectroscopy with heated attenuated total internal reflectance enabling precise measurement of thermally induced transitions in complex biological polymers. Analytical Chemistry. 85: 3999-4006. PMID 23461675 DOI: 10.1021/Ac303552S  0.357
2012 Warren FJ, Royall PG, Butterworth PJ, Ellis PR. Immersion mode material pocket dynamic mechanical analysis (IMP-DMA): a novel tool to study gelatinisation of purified starches and starch-containing plant materials. Carbohydrate Polymers. 90: 628-36. PMID 24751086 DOI: 10.1016/J.Carbpol.2012.05.088  0.385
2012 Mercuri A, Belton PS, Royall PG, Barker SA. Identification and molecular interpretation of the effects of drug incorporation on the self-emulsification process using spectroscopic, micropolarimetric and microscopic measurements. Molecular Pharmaceutics. 9: 2658-68. PMID 22913291 DOI: 10.1021/Mp300219H  0.343
2012 Jawad R, Elleman C, Vermeer L, Drake AF, Woodhead B, Martin GP, Royall PG. The measurement of the β/α anomer composition within amorphous lactose prepared by spray and freeze drying using a simple (1)H-NMR method. Pharmaceutical Research. 29: 511-24. PMID 21901569 DOI: 10.1007/S11095-011-0575-6  0.754
2011 Kaialy W, Martin GP, Ticehurst MD, Royall P, Mohammad MA, Murphy J, Nokhodchi A. Characterisation and deposition studies of recrystallised lactose from binary mixtures of ethanol/butanol for improved drug delivery from dry powder inhalers. The Aaps Journal. 13: 30-43. PMID 21057906 DOI: 10.1208/S12248-010-9241-X  0.412
2011 Royall P, Woodhead B, Tang S, Martin G, Stockton B, Murnane D. Formation and measurement of process induced disorder during the manufacture of inhalation medicines Journal of Drug Delivery Science and Technology. 21: 311-318. DOI: 10.1016/S1773-2247(11)50048-6  0.752
2011 Warren FJ, Royall PG, Gaisford S, Butterworth PJ, Ellis PR. Binding interactions of α-amylase with starch granules: The influence of supramolecular structure and surface area Carbohydrate Polymers. 86: 1038-1047. DOI: 10.1016/J.Carbpol.2011.05.062  0.307
2009 Gaisford S, Verma A, Saunders M, Royall PG. Monitoring crystallisation of drugs from fast-dissolving oral films with isothermal calorimetry. International Journal of Pharmaceutics. 380: 105-11. PMID 19596058 DOI: 10.1016/J.Ijpharm.2009.07.006  0.328
2009 Mahlin D, Wood J, Hawkins N, Mahey J, Royall PG. A novel powder sample holder for the determination of glass transition temperatures by DMA. International Journal of Pharmaceutics. 371: 120-5. PMID 19167475 DOI: 10.1016/J.Ijpharm.2008.12.039  0.318
2005 Royall PG, Huang CY, Tang SW, Duncan J, Van-de-Velde G, Brown MB. The development of DMA for the detection of amorphous content in pharmaceutical powdered materials. International Journal of Pharmaceutics. 301: 181-91. PMID 16026947 DOI: 10.1016/J.Ijpharm.2005.05.015  0.362
2005 Ramos R, Gaisford S, Buckton G, Royall PG, Yff BT, O'Neill MA. A comparison of chemical reference materials for solution calorimeters. International Journal of Pharmaceutics. 299: 73-83. PMID 15975746 DOI: 10.1016/J.Ijpharm.2005.04.027  0.317
2005 Royall PG, Gaisford S. Application of solution calorimetry in pharmaceutical and biopharmaceutical research. Current Pharmaceutical Biotechnology. 6: 215-22. PMID 15974976 DOI: 10.2174/1389201054022887  0.317
2005 Jones SA, Martin GP, Royall PG, Brown MB. Biocompatible polymer blends: Effects of physical processing on the molecular interaction of poly(vinyl alcohol) and poly(vinyl pyrrolidone) Journal of Applied Polymer Science. 98: 2290-2299. DOI: 10.1002/App.22390  0.326
2004 Saunders M, Podluii K, Shergill S, Buckton G, Royall P. The potential of high speed DSC (hyper-DSC) for the detection and quantification of small amounts of amorphous content in predominantly crystalline samples. International Journal of Pharmaceutics. 274: 35-40. PMID 15072780 DOI: 10.1016/J.Ijpharm.2004.01.018  0.317
2004 Yff BT, Royall PG, Brown MB, Martin GP. An investigation of calibration methods for solution calorimetry. International Journal of Pharmaceutics. 269: 361-72. PMID 14706248 DOI: 10.1016/J.Ijpharm.2003.09.011  0.314
2004 Zaman MA, Martin GP, Rees GD, Royall PG. The effect of hydration on the thermal behaviour of hydrophilic non-aqueous gels stabilised by Carbopol 974P Thermochimica Acta. 417: 251-255. DOI: 10.1016/J.Tca.2003.09.032  0.328
2002 Craig DQM, Kett VL, Andrews CS, Royall PG. Pharmaceutical applications of micro-thermal analysis Journal of Pharmaceutical Sciences. 91: 1201-1213. PMID 11977096 DOI: 10.1002/Jps.10103  0.324
2002 Van Den Mooter G, Craig DQ, Royall PG. Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetry. Journal of Pharmaceutical Sciences. 90: 996-1003. PMID 11536203 DOI: 10.1002/Jps.1052  0.593
2001 Royall PG, Hill VL, Craig DQ, Price DM, Reading M. An investigation into the surface deposition of progesterone on poly (d,l-) lactic acid microspheres using micro-thermal analysis. Pharmaceutical Research. 18: 294-8. PMID 11442267 DOI: 10.1023/A:1011094611784  0.642
2001 Royall PG, Kett VL, Andrews CS, Craig DQM. Identification of crystalline and amorphous regions in low molecular weight materials using microthermal analysis Journal of Physical Chemistry B. 105: 7021-7026. DOI: 10.1021/Jp010441K  0.377
2001 Royall PG, Craig DQ, Grandy DB. The use of micro-thermal analysis as a means of in situ characterisation of a pharmaceutical tablet coat Thermochimica Acta. 380: 165-173. DOI: 10.1016/S0040-6031(01)00667-0  0.603
2000 Craig DQ, Barsnes M, Royall PG, Kett VL. An evaluation of the use of modulated temperature DSC as a means of assessing the relaxation behaviour of amorphous lactose. Pharmaceutical Research. 17: 696-700. PMID 10955843 DOI: 10.1023/A:1007578131582  0.606
2000 Royall PG, Craig DQ, Price DM, Reading M, Lever TJ. An investigation into the use of micro-thermal analysis for the solid state characterisation of an HPMC tablet formulation. International Journal of Pharmaceutics. 192: 97-103. PMID 10572203 DOI: 10.1016/S0378-5173(99)00276-8  0.606
2000 Saklatvala R, Royall PG, Craig DQ. The detection of amorphous material in a nominally crystalline drug using modulated temperature DSC--a case study. International Journal of Pharmaceutics. 192: 55-62. PMID 10572199 DOI: 10.1016/S0378-5173(99)00272-0  0.647
2000 Royall PG, Craig DQ, Doherty C. Characterisation of moisture uptake effects on the glass transitional behaviour of an amorphous drug using modulated temperature DSC. International Journal of Pharmaceutics. 192: 39-46. PMID 10572197 DOI: 10.1016/S0378-5173(99)00270-7  0.62
1999 McPhillips H, Craig DQ, Royall PG, Hill VL. Characterisation of the glass transition of HPMC using modulated temperature differential scanning calorimetry. International Journal of Pharmaceutics. 180: 83-90. PMID 10089295 DOI: 10.1016/S0378-5173(98)00407-4  0.611
1999 Craig DQ, Royall PG, Kett VL, Hopton ML. The relevance of the amorphous state to pharmaceutical dosage forms: glassy drugs and freeze dried systems. International Journal of Pharmaceutics. 179: 179-207. PMID 10053213 DOI: 10.1016/S0378-5173(98)00338-X  0.627
1998 Craig DQ, Royall PG. The use of modulated temperature DSC for the study of pharmaceutical systems: potential uses and limitations. Pharmaceutical Research. 15: 1152-3. PMID 9706042 DOI: 10.1023/A:1011967202972  0.58
1998 Royall PG, Craig DQ, Doherty C. Characterisation of the glass transition of an amorphous drug using modulated DSC. Pharmaceutical Research. 15: 1117-21. PMID 9688069 DOI: 10.1023/A:1011902816175  0.625
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