Year |
Citation |
Score |
2022 |
Gildea HK, Frankino PA, Tronnes SU, Pender CL, Durieux J, Dishart JG, Choi HO, Hunter TD, Cheung SS, Frakes AE, Sukarto E, Wickham K, Dillin A. Glia of coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit. Science Advances. 8: eabq3970. PMID 36490338 DOI: 10.1126/sciadv.abq3970 |
0.708 |
|
2022 |
Ward CP, Peng L, Yuen S, Halstead J, Palacios H, Nyangau E, Mohammed H, Ziari N, Dandan M, Frakes AE, Gildea HK, Dillin A, Hellerstein MK. Aging alters the metabolic flux signature of the ER-unfolded protein response in vivo in mice. Aging Cell. e13558. PMID 35170180 DOI: 10.1111/acel.13558 |
0.767 |
|
2022 |
Ward CP, Peng L, Yuen S, Chang M, Karapetyan R, Nyangau E, Mohammed H, Palacios H, Ziari N, Joe LK, Frakes AE, Dandan M, Dillin A, Hellerstein MK. ER Unfolded Protein Response in Liver In Vivo Is Characterized by Reduced, Not Increased, De Novo Lipogenesis and Cholesterol Synthesis Rates with Uptake of Fatty Acids from Adipose Tissue: Integrated Gene Expression, Translation Rates and Metabolic Fluxes. International Journal of Molecular Sciences. 23. PMID 35162995 DOI: 10.3390/ijms23031073 |
0.544 |
|
2020 |
Bar-Ziv R, Frakes AE, Higuchi-Sanabria R, Bolas T, Frankino PA, Gildea HK, Metcalf MG, Dillin A. Measurements of Physiological Stress Responses in C. Elegans. Journal of Visualized Experiments : Jove. PMID 32510480 DOI: 10.3791/61001 |
0.642 |
|
2020 |
Frakes AE, Metcalf MG, Tronnes SU, Bar-Ziv R, Durieux J, Gildea HK, Kandahari N, Monshietehadi S, Dillin A. Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in . Science (New York, N.Y.). 367: 436-440. PMID 31974253 DOI: 10.1126/Science.Aaz6896 |
0.688 |
|
2017 |
Frakes AE, Dillin A. The UPR(ER): Sensor and Coordinator of Organismal Homeostasis. Molecular Cell. 66: 761-771. PMID 28622521 DOI: 10.1016/J.Molcel.2017.05.031 |
0.679 |
|
2017 |
Frakes AE, Braun L, Ferraiuolo L, Guttridge DC, Kaspar BK. Additive amelioration of ALS by co-targeting independent pathogenic mechanisms. Annals of Clinical and Translational Neurology. 4: 76-86. PMID 28168207 DOI: 10.1002/Acn3.375 |
0.6 |
|
2016 |
Ferraiuolo L, Meyer K, Sherwood TW, Vick J, Likhite S, Frakes A, Miranda CJ, Braun L, Heath PR, Pineda R, Beattie CE, Shaw PJ, Askwith CC, McTigue D, Kaspar BK. Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 27688759 DOI: 10.1073/Pnas.1607496113 |
0.618 |
|
2016 |
Ahmed SS, Schattgen SA, Frakes AE, Sikoglu EM, Su Q, Li J, Hampton TG, Denninger AR, Kirschner DA, Kaspar B, Matalon R, Gao G. rAAV gene therapy in a Canavan's disease mouse model reveals immune impairments and an extended pathology beyond the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27039844 DOI: 10.1038/Mt.2016.68 |
0.551 |
|
2016 |
Song S, Miranda CJ, Braun L, Meyer K, Frakes AE, Ferraiuolo L, Likhite S, Bevan AK, Foust KD, McConnell MJ, Walker CM, Kaspar BK. Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis. Nature Medicine. PMID 26928464 DOI: 10.1038/Nm.4052 |
0.731 |
|
2016 |
Gu JM, Wang DJ, Peterson JM, Shintaku J, Liyanarachchi S, Coppola V, Frakes AE, Kaspar BK, Cornelison DD, Guttridge DC. An NF-κB - EphrinA5-Dependent Communication between NG2(+) Interstitial Cells and Myoblasts Promotes Muscle Growth in Neonates. Developmental Cell. PMID 26777211 DOI: 10.1016/J.Devcel.2015.12.018 |
0.54 |
|
2014 |
Frakes AE, Ferraiuolo L, Haidet-Phillips AM, Schmelzer L, Braun L, Miranda CJ, Ladner KJ, Bevan AK, Foust KD, Godbout JP, Popovich PG, Guttridge DC, Kaspar BK. Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis. Neuron. 81: 1009-23. PMID 24607225 DOI: 10.1016/J.Neuron.2014.01.013 |
0.727 |
|
2013 |
Ferraiuolo L, Frakes A, Kaspar BK. Neural stem cells as a therapeutic approach for amyotrophic lateral sclerosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 503-5. PMID 23449106 DOI: 10.1038/Mt.2013.24 |
0.592 |
|
2011 |
Fidler JA, Treleaven CM, Frakes A, Tamsett TJ, McCrate M, Cheng SH, Shihabuddin LS, Kaspar BK, Dodge JC. Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4369-77. PMID 21876068 DOI: 10.1096/Fj.11-190819 |
0.656 |
|
2011 |
Haidet-Phillips AM, Hester ME, Miranda CJ, Meyer K, Braun L, Frakes A, Song S, Likhite S, Murtha MJ, Foust KD, Rao M, Eagle A, Kammesheidt A, Christensen A, Mendell JR, et al. Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nature Biotechnology. 29: 824-8. PMID 21832997 DOI: 10.1038/Nbt.1957 |
0.724 |
|
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