| Year |
Citation |
Score |
| 2023 |
Burger WAC, Pham V, Vuckovic Z, Powers AS, Mobbs JI, Laloudakis Y, Glukhova A, Wootten D, Tobin AB, Sexton PM, Paul SM, Felder CC, Danev R, Dror RO, Christopoulos A, et al. Xanomeline displays concomitant orthosteric and allosteric binding modes at the M mAChR. Nature Communications. 14: 5440. PMID 37673901 DOI: 10.1038/s41467-023-41199-5 |
0.334 |
|
| 2023 |
Powers AS, Pham V, Burger WAC, Thompson G, Laloudakis Y, Sexton PM, Paul SM, Christopoulos A, Thal DM, Felder CC, Valant C, Dror RO. Structural basis of efficacy-driven ligand selectivity at GPCRs. Nature Chemical Biology. PMID 36782010 DOI: 10.1038/s41589-022-01247-5 |
0.359 |
|
| 2022 |
Yohn SE, Weiden PJ, Felder CC, Stahl SM. Muscarinic acetylcholine receptors for psychotic disorders: bench-side to clinic. Trends in Pharmacological Sciences. 43: 1098-1112. PMID 36273943 DOI: 10.1016/j.tips.2022.09.006 |
0.312 |
|
| 2022 |
McDonald JK, van der Westhuizen ET, Pham V, Thompson G, Felder CC, Paul SM, Thal DM, Christopoulos A, Valant C. Biased Profile of Xanomeline at the Recombinant Human M Muscarinic Acetylcholine Receptor. Acs Chemical Neuroscience. PMID 35380782 DOI: 10.1021/acschemneuro.1c00827 |
0.407 |
|
| 2020 |
Montani C, Canella C, Schwarz AJ, Li J, Gilmour G, Galbusera A, Wafford K, Gutierrez-Barragan D, McCarthy A, Shaw D, Knitowski K, McKinzie D, Gozzi A, Felder C. The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33342996 DOI: 10.1038/s41386-020-00916-0 |
0.344 |
|
| 2019 |
Hollingsworth SA, Kelly B, Valant C, Michaelis JA, Mastromihalis O, Thompson G, Venkatakrishnan AJ, Hertig S, Scammells PJ, Sexton PM, Felder CC, Christopoulos A, Dror RO. Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs. Nature Communications. 10: 3289. PMID 31337749 DOI: 10.1038/s41467-019-11062-7 |
0.431 |
|
| 2019 |
Knopp KL, Simmons RMA, Guo W, Adams BL, Gardinier KM, Gernert DL, Ornstein PL, Porter W, Reel J, Ding C, Wang H, Qian Y, Burris KD, Need A, Barth V, ... ... Felder CC, et al. Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 30910921 DOI: 10.1124/Jpet.118.250126 |
0.456 |
|
| 2019 |
Birdsall NJM, Bradley S, Brown DA, Buckley NJ, Challiss RJ, Christopoulos A, Eglen RM, Ehlert F, Felder CC, Hammer R, Kilbinger HJ, Lambrecht G, Langmead C, Mitchelson F, Mutschler E, et al. Acetylcholine receptors (muscarinic) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f2/2019.4 |
0.463 |
|
| 2019 |
Abood M, Alexander SP, Barth F, Bonner TI, Bradshaw H, Cabral G, Casellas P, Cravatt BF, Devane WA, Di Marzo V, Elphick MR, Felder CC, Greasley P, Herkenham M, Howlett AC, et al. Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f13/2019.4 |
0.419 |
|
| 2018 |
Broad LM, Sanger HE, Mogg AJ, Colvin EM, Zwart R, Evans DA, Pasqui F, Sher E, Wishart GN, Barth VN, Felder CC, Goldsmith PJ. Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant M1 muscarinic acetylcholine receptor agonist. British Journal of Pharmacology. PMID 30276808 DOI: 10.1111/Bph.14510 |
0.53 |
|
| 2018 |
Bradley SJ, Molloy C, Bundgaard C, Mogg AJ, Thompson KJ, Dwomoh L, Sanger HE, Crabtree M, Brooke SM, Sexton PM, Felder CC, Christopoulos A, Broad LM, Tobin AB, Langmead CJ. Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes. Molecular Pharmacology. PMID 29695609 DOI: 10.1124/Mol.118.111872 |
0.506 |
|
| 2018 |
Mogg AJ, Eessalu T, Johnson M, Wright R, Sanger HE, Xiou H, Crabtree M, Smith A, Colvin E, Schober D, Gehlert D, Jesudason C, Goldsmith P, Johnson MP, Felder CC, et al. pharmacological characterization and validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography (PET). The Journal of Pharmacology and Experimental Therapeutics. PMID 29643252 DOI: 10.1124/Jpet.117.246454 |
0.477 |
|
| 2018 |
Felder CC, Goldsmith PJ, Jackson K, Sanger HE, Evans DA, Mogg AJ, Broad LM. Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases. Neuropharmacology. PMID 29374561 DOI: 10.1016/J.Neuropharm.2018.01.028 |
0.499 |
|
| 2017 |
Schober DA, Croy CH, Ruble CL, Tao R, Felder CC. Identification, expression and functional characterization of M4L, a muscarinic acetylcholine M4 receptor splice variant. Plos One. 12: e0188330. PMID 29211764 DOI: 10.1371/Journal.Pone.0188330 |
0.537 |
|
| 2017 |
Martin AE, Schober DA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Laksmanan A, Catlow JT, Li X, Felder CC, Witkin JM. Further evaluation of mechanisms associated with the antidepressant-like signature of scopolamine in mice. Cns & Neurological Disorders Drug Targets. PMID 28294051 DOI: 10.2174/1871527316666170309142646 |
0.371 |
|
| 2017 |
Felder CC, Schober DA, Tu Y, Quets AT, Xiao H, Watt M, Siuda ER, Nisenbaum ES, Xiang C, Heinz B, Prieto L, Mc Kinzie DL, Monn JA. Translational pharmacology of the mGluR2-preferring agonist LY2812223 in animal and human brain. The Journal of Pharmacology and Experimental Therapeutics. PMID 28138041 DOI: 10.1124/Jpet.116.237859 |
0.522 |
|
| 2016 |
Bradley SJ, Bourgognon JM, Sanger HE, Verity N, Mogg AJ, White DJ, Butcher AJ, Moreno JA, Molloy C, Macedo-Hatch T, Edwards JM, Wess J, Pawlak R, Read DJ, Sexton PM, ... ... Felder CC, et al. M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss. The Journal of Clinical Investigation. PMID 27991860 DOI: 10.1172/Jci87526 |
0.408 |
|
| 2016 |
Croy CH, Chan WY, Castetter AM, Watt ML, Quets AT, Felder CC. Characterization of PCS1055, a Novel Muscarinic M4 Receptor Antagonist. European Journal of Pharmacology. PMID 27085897 DOI: 10.1016/J.Ejphar.2016.04.022 |
0.537 |
|
| 2016 |
Thal DM, Sun B, Feng D, Nawaratne V, Leach K, Felder CC, Bures MG, Evans DA, Weis WI, Bachhawat P, Kobilka TS, Sexton PM, Kobilka BK, Christopoulos A. Crystal structures of the M1 and M4 muscarinic acetylcholine receptors. Nature. PMID 26958838 DOI: 10.1038/Nature17188 |
0.538 |
|
| 2016 |
Butcher AJ, Bradley SJ, Prihandoko R, Brooke SM, Mogg A, Bourgognon JM, Macedo-Hatch T, Edwards JM, Bottrill AR, Challiss RA, Broad LM, Felder CC, Tobin AB. An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory. The Journal of Biological Chemistry. 291: 8862-75. PMID 26826123 DOI: 10.1074/Jbc.M115.681726 |
0.489 |
|
| 2015 |
Dennis SH, Pasqui F, Colvin EM, Sanger H, Mogg AJ, Felder CC, Broad LM, Fitzjohn SM, Isaac JT, Mellor JR. Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). PMID 26472558 DOI: 10.1093/Cercor/Bhv227 |
0.355 |
|
| 2015 |
Liu B, Croy CH, Hitchcock SA, Allen JR, Rao Z, Evans D, Bures MG, McKinzie DL, Watt ML, Stuart Gregory G, Hansen MM, Hoogestraat PJ, Jamison JA, Okha-Mokube FM, Stratford RE, ... ... Felder CC, et al. Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists. Bioorganic & Medicinal Chemistry Letters. PMID 26299349 DOI: 10.1016/J.Bmcl.2015.08.011 |
0.491 |
|
| 2015 |
Andersen MB, Croy CH, Dencker D, Werge T, Bymaster FP, Felder CC, Fink-Jensen A. Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates. Plos One. 10: e0122722. PMID 25880220 DOI: 10.1371/Journal.Pone.0122722 |
0.534 |
|
| 2015 |
Bakker G, Vingerhoets WA, van Wieringen JP, de Bruin K, Eersels J, de Jong J, Chahid Y, Rutten BP, DuBois S, Watson M, Mogg AJ, Xiao H, Crabtree M, Collier DA, Felder CC, et al. 123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 317-22. PMID 25593117 DOI: 10.2967/Jnumed.114.147488 |
0.464 |
|
| 2015 |
Gitschier HJ, Bergeron AB, Randle DH, Bacon CE, Baez M, Yang P, Broad LM, Goldsmith PJ, Felder CC, Schober DA. Triple-addition label-free assays for high-throughput screening of muscarinic M1 receptor agonists, antagonists, and allosteric modulators Label-Free Biosensor Methods in Drug Discovery. 197-214. DOI: 10.1007/978-1-4939-2617-6_11 |
0.326 |
|
| 2014 |
Witkin JM, Overshiner C, Li X, Catlow JT, Wishart GN, Schober DA, Heinz BA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Felder CC. M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine. The Journal of Pharmacology and Experimental Therapeutics. 351: 448-56. PMID 25187432 DOI: 10.1124/Jpet.114.216804 |
0.536 |
|
| 2014 |
Schober DA, Croy CH, Xiao H, Christopoulos A, Felder CC. Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites. Molecular Pharmacology. 86: 116-23. PMID 24807966 DOI: 10.1124/Mol.114.091785 |
0.458 |
|
| 2014 |
Croy CH, Schober DA, Xiao H, Quets A, Christopoulos A, Felder CC. Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors. Molecular Pharmacology. 86: 106-15. PMID 24807965 DOI: 10.1124/Mol.114.091751 |
0.555 |
|
| 2014 |
Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons. Psychopharmacology. 231: 1105-24. PMID 24429870 DOI: 10.1007/S00213-013-3384-2 |
0.342 |
|
| 2013 |
Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, et al. Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature. 504: 101-6. PMID 24256733 DOI: 10.1038/Nature12735 |
0.52 |
|
| 2013 |
Watt ML, Rorick-Kehn L, Shaw DB, Knitowski KM, Quets AT, Chesterfield AK, McKinzie DL, Felder CC. The muscarinic acetylcholine receptor agonist BuTAC mediates antipsychotic-like effects via the M4 subtype. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2717-26. PMID 23907402 DOI: 10.1038/Npp.2013.186 |
0.52 |
|
| 2013 |
Gibbons AS, Scarr E, Boer S, Money T, Jeon WJ, Felder C, Dean B. Widespread decreases in cortical muscarinic receptors in a subset of people with schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 37-46. PMID 22338582 DOI: 10.1017/S1461145712000028 |
0.379 |
|
| 2012 |
Valant C, Felder CC, Sexton PM, Christopoulos A. Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects. Molecular Pharmacology. 81: 41-52. PMID 21989256 DOI: 10.1124/Mol.111.074872 |
0.489 |
|
| 2011 |
Watt ML, Schober DA, Hitchcock S, Liu B, Chesterfield AK, McKinzie D, Felder CC. Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist. The Journal of Pharmacology and Experimental Therapeutics. 338: 622-32. PMID 21558436 DOI: 10.1124/Jpet.111.182063 |
0.502 |
|
| 2011 |
Schober DA, Gill MB, Yu H, Gernert DL, Jeffries MW, Ornstein PL, Kato AS, Felder CC, Bredt DS. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of Biological Chemistry. 286: 13134-42. PMID 21343286 DOI: 10.1074/Jbc.M110.212522 |
0.537 |
|
| 2011 |
Leach K, Davey AE, Felder CC, Sexton PM, Christopoulos A. The role of transmembrane domain 3 in the actions of orthosteric, allosteric, and atypical agonists of the M4 muscarinic acetylcholine receptor. Molecular Pharmacology. 79: 855-65. PMID 21300722 DOI: 10.1124/Mol.111.070938 |
0.518 |
|
| 2011 |
Suratman S, Leach K, Sexton P, Felder C, Loiacono R, Christopoulos A. Impact of species variability and 'probe-dependence' on the detection and in vivo validation of allosteric modulation at the M4 muscarinic acetylcholine receptor. British Journal of Pharmacology. 162: 1659-70. PMID 21198541 DOI: 10.1111/J.1476-5381.2010.01184.X |
0.497 |
|
| 2011 |
Fell MJ, Witkin JM, Falcone JF, Katner JS, Perry KW, Hart J, Rorick-Kehn L, Overshiner CD, Rasmussen K, Chaney SF, Benvenga MJ, Li X, Marlow DL, Thompson LK, Luecke SK, ... ... Felder CC, et al. N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes. The Journal of Pharmacology and Experimental Therapeutics. 336: 165-77. PMID 20947638 DOI: 10.1124/Jpet.110.172957 |
0.358 |
|
| 2010 |
Suter TM, Chesterfield AK, Bao C, Schaus JM, Krushinski JH, Statnick MA, Felder CC. Pharmacological characterization of the cannabinoid CB₁ receptor PET ligand ortholog, [³H]MePPEP. European Journal of Pharmacology. 649: 44-50. PMID 20851117 DOI: 10.1016/J.Ejphar.2010.08.055 |
0.52 |
|
| 2010 |
Nawaratne V, Leach K, Felder CC, Sexton PM, Christopoulos A. Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms. The Journal of Biological Chemistry. 285: 19012-21. PMID 20406819 DOI: 10.1074/Jbc.M110.125096 |
0.513 |
|
| 2010 |
Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ. Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease. Journal of Chemical Neuroanatomy. 40: 63-70. PMID 20347961 DOI: 10.1016/J.Jchemneu.2010.03.005 |
0.45 |
|
| 2010 |
Terry GE, Hirvonen J, Liow JS, Seneca N, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Pike VW, Halldin C, Innis RB. Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1499-506. PMID 20333514 DOI: 10.1007/S00259-010-1411-7 |
0.343 |
|
| 2010 |
Terry GE, Hirvonen J, Liow JS, Zoghbi SS, Gladding R, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Donohue SR, Pike VW, Halldin C, Innis RB. Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 112-20. PMID 20008988 DOI: 10.2967/Jnumed.109.067074 |
0.322 |
|
| 2010 |
Leach K, Loiacono RE, Felder CC, McKinzie DL, Mogg A, Shaw DB, Sexton PM, Christopoulos A. Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 855-69. PMID 19940843 DOI: 10.1038/Npp.2009.194 |
0.527 |
|
| 2009 |
Terry GE, Liow JS, Zoghbi SS, Hirvonen J, Farris AG, Lerner A, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Hong JS, Pike VW, Halldin C, Innis RB. Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand. Neuroimage. 48: 362-70. PMID 19573609 DOI: 10.1016/J.Neuroimage.2009.06.059 |
0.37 |
|
| 2008 |
Donohue SR, Krushinski JH, Pike VW, Chernet E, Phebus L, Chesterfield AK, Felder CC, Halldin C, Schaus JM. Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging. Journal of Medicinal Chemistry. 51: 5833-42. PMID 18800770 DOI: 10.1021/Jm800416M |
0.42 |
|
| 2008 |
Chan WY, McKinzie DL, Bose S, Mitchell SN, Witkin JM, Thompson RC, Christopoulos A, Lazareno S, Birdsall NJ, Bymaster FP, Felder CC. Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 105: 10978-83. PMID 18678919 DOI: 10.1073/Pnas.0800567105 |
0.536 |
|
| 2008 |
Nawaratne V, Leach K, Suratman N, Loiacono RE, Felder CC, Armbruster BN, Roth BL, Sexton PM, Christopoulos A. New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug). Molecular Pharmacology. 74: 1119-31. PMID 18628403 DOI: 10.1124/Mol.108.049353 |
0.525 |
|
| 2008 |
Shekhar A, Potter WZ, Lightfoot J, Lienemann J, Dubé S, Mallinckrodt C, Bymaster FP, McKinzie DL, Felder CC. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. The American Journal of Psychiatry. 165: 1033-9. PMID 18593778 DOI: 10.1176/Appi.Ajp.2008.06091591 |
0.314 |
|
| 2008 |
Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34. PMID 18492727 DOI: 10.1096/Fj.07-101865 |
0.345 |
|
| 2008 |
Terry G, Liow JS, Chernet E, Zoghbi SS, Phebus L, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. Neuroimage. 41: 690-8. PMID 18456516 DOI: 10.1016/J.Neuroimage.2008.03.004 |
0.467 |
|
| 2008 |
Yasuno F, Brown AK, Zoghbi SS, Krushinski JH, Chernet E, Tauscher J, Schaus JM, Phebus LA, Chesterfield AK, Felder CC, Gladding RL, Hong J, Halldin C, Pike VW, Innis RB. The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 259-69. PMID 17392732 DOI: 10.1038/Sj.Npp.1301402 |
0.449 |
|
| 2008 |
Terry GE, Liow J-, Chernet E, Zoghbi SS, Phebus L, Lerner A, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Evaluation of an inverse agonist with high affinity for the CB1 receptor, [11C]MePPEP, in rodents and humans Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.164 |
0.466 |
|
| 2006 |
Felder CC, Dickason-Chesterfield AK, Moore SA. Cannabinoids biology: the search for new therapeutic targets. Molecular Interventions. 6: 149-61. PMID 16809476 DOI: 10.1124/Mi.6.3.6 |
0.318 |
|
| 2006 |
Dickason-Chesterfield AK, Kidd SR, Moore SA, Schaus JM, Liu B, Nomikos GG, Felder CC. Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. Cellular and Molecular Neurobiology. 26: 407-23. PMID 16736384 DOI: 10.1007/S10571-006-9072-6 |
0.307 |
|
| 2006 |
Felder CC. Endocannabinoids and their receptors as targets for treating metabolic and psychiatric disorders Drug Discovery Today: Therapeutic Strategies. 3: 561-567. DOI: 10.1016/J.Ddstr.2006.10.015 |
0.397 |
|
| 2005 |
Moore SA, Nomikos GG, Dickason-Chesterfield AK, Schober DA, Schaus JM, Ying BP, Xu YC, Phebus L, Simmons RM, Li D, Iyengar S, Felder CC. Identification of a high-affinity binding site involved in the transport of endocannabinoids. Proceedings of the National Academy of Sciences of the United States of America. 102: 17852-7. PMID 16314570 DOI: 10.1073/Pnas.0507470102 |
0.382 |
|
| 2004 |
Felder CC. Strategic Research Institute G-Protein-Coupled Receptors Drug Discovery World Summit. Expert Opinion On Investigational Drugs. 13: 1071-4. PMID 15268643 DOI: 10.1517/13543784.13.8.1071 |
0.351 |
|
| 2004 |
Tzavara ET, Bymaster FP, Davis RJ, Wade MR, Perry KW, Wess J, McKinzie DL, Felder C, Nomikos GG. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1410-2. PMID 15231726 DOI: 10.1096/Fj.04-1575Fje |
0.363 |
|
| 2003 |
Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL. Muscarinic mechanisms of antipsychotic atypicality. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 1125-43. PMID 14642972 DOI: 10.1016/J.Pnpbp.2003.09.008 |
0.561 |
|
| 2003 |
Wess J, Duttaroy A, Zhang W, Gomeza J, Cui Y, Miyakawa T, Bymaster FP, McKinzie L, Felder CC, Lamping KG, Faraci FM, Deng C, Yamada M. M1-M5 muscarinic receptor knockout mice as novel tools to study the physiological roles of the muscarinic cholinergic system. Receptors & Channels. 9: 279-90. PMID 12893539 DOI: 10.1080/10606820308262 |
0.373 |
|
| 2003 |
Tzavara ET, Bymaster FP, Felder CC, Wade M, Gomeza J, Wess J, McKinzie DL, Nomikos GG. Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice. Molecular Psychiatry. 8: 673-9. PMID 12874603 DOI: 10.1038/sj.mp.4001270 |
0.333 |
|
| 2003 |
Bymaster FP, Carter PA, Yamada M, Gomeza J, Wess J, Hamilton SE, Nathanson NM, McKinzie DL, Felder CC. Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. The European Journal of Neuroscience. 17: 1403-10. PMID 12713643 DOI: 10.1046/J.1460-9568.2003.02588.X |
0.446 |
|
| 2003 |
Bymaster FP, McKinzie DL, Felder CC, Wess J. Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system. Neurochemical Research. 28: 437-42. PMID 12675128 DOI: 10.1023/A:1022844517200 |
0.482 |
|
| 2003 |
Wess J, Duttaroy A, Gomeza J, Zhang W, Yamada M, Felder CC, Bernardini N, Reeh PW. Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: A review Life Sciences. 72: 2047-2054. PMID 12628455 DOI: 10.1016/S0024-3205(03)00082-1 |
0.574 |
|
| 2003 |
Wess J, Duttaroy A, Zhang W, Gomeza J, Cui Y, Miyakawa T, Bymaster FP, Mckinzie L, Felder CC, Lamping KG, Faraci FM, Deng C, Yamada M. M 1 -M 5 Muscarinic Receptor Knockout Mice as Novel Tools to Study the Physiological Roles of the Muscarinic Cholinergic System Receptors and Channels. 9: 279-290. DOI: 10.3109/10606820308262 |
0.387 |
|
| 2002 |
Bymaster FP, Felder C, Ahmed S, McKinzie D. Muscarinic receptors as a target for drugs treating schizophrenia. Current Drug Targets. Cns and Neurological Disorders. 1: 163-81. PMID 12769625 DOI: 10.2174/1568007024606249 |
0.464 |
|
| 2002 |
Duttaroy A, Gomeza J, Gan JW, Siddiqui N, Basile AS, Harman WD, Smith PL, Felder CC, Levey AI, Wess J. Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice. Molecular Pharmacology. 62: 1084-93. PMID 12391271 DOI: 10.1124/Mol.62.5.1084 |
0.533 |
|
| 2002 |
Hemrick-Luecke SK, Bymaster FP, Evans DC, Wess J, Felder CC. Muscarinic agonist-mediated increases in serum corticosterone levels are abolished in m(2) muscarinic acetylcholine receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 99-103. PMID 12235238 DOI: 10.1124/Jpet.102.036020 |
0.516 |
|
| 2002 |
Porter AC, Bymaster FP, DeLapp NW, Yamada M, Wess J, Hamilton SE, Nathanson NM, Felder CC. M1 muscarinic receptor signaling in mouse hippocampus and cortex. Brain Research. 944: 82-9. PMID 12106668 DOI: 10.1016/S0006-8993(02)02721-X |
0.541 |
|
| 2002 |
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161 |
0.553 |
|
| 2002 |
Porter AC, Sauer JM, Knierman MD, Becker GW, Berna MJ, Bao J, Nomikos GG, Carter P, Bymaster FP, Leese AB, Felder CC. Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor Journal of Pharmacology and Experimental Therapeutics. 301: 1020-1024. PMID 12023533 DOI: 10.1124/Jpet.301.3.1020 |
0.553 |
|
| 2002 |
Bymaster FP, Felder CC. Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents. Molecular Psychiatry. 7: S57-63. PMID 11986996 DOI: 10.1038/sj.mp.4001019 |
0.456 |
|
| 2002 |
Lin P, Kusano K, Zhang Q, Felder CC, Geiger PM, Mahan LC. GABAA Receptors Modulate Early Spontaneous Excitatory Activity in Differentiating P19 Neurons Journal of Neurochemistry. 66: 233-242. PMID 8522959 DOI: 10.1046/J.1471-4159.1996.66010233.X |
0.316 |
|
| 2002 |
Gomeza J, Yamada M, Duttaroy A, Zhang W, Makita R, Miyakawa T, Crawley J, Zhang L, Shannon H, Bymaster FP, Felder CC, Deng C, Wess J. Muscarinic acetylcholine receptor knockout mice: Phenotypical analysis and clinical implications Pharmacochemistry Library. 32: 97-113. DOI: 10.1016/S0165-7208(02)80012-5 |
0.482 |
|
| 2001 |
Kennedy JS, Bymaster FP, Schuh L, Calligaro DO, Nomikos G, Felder CC, Bernauer M, Kinon BJ, Baker RW, Hay D, Roth HJ, Dossenbach M, Kaiser C, Beasley CM, Holcombe JH, et al. A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data. International Journal of Geriatric Psychiatry. 16: S33-61. PMID 11748788 DOI: 10.1002/1099-1166(200112)16:1+<::Aid-Gps571>3.0.Co;2-5 |
0.331 |
|
| 2001 |
Stamer WD, Golightly SF, Hosohata Y, Ryan EP, Porter AC, Varga E, Noecker RJ, Felder CC, Yamamura HI. Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. European Journal of Pharmacology. 431: 277-86. PMID 11730719 DOI: 10.1016/S0014-2999(01)01438-8 |
0.483 |
|
| 2001 |
Yamada M, Lamping KG, Duttaroy A, Zhang W, Cui Y, Bymaster FP, McKinzie DL, Felder CC, Deng CX, Faraci FM, Wess J. Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 14096-101. PMID 11707605 DOI: 10.1073/Pnas.251542998 |
0.527 |
|
| 2001 |
Bymaster FP, Carter PA, DeLapp NW, Calligaro DO, Felder CC. Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo Brain Research. 916: 165-171. PMID 11597604 DOI: 10.1016/S0006-8993(01)02889-X |
0.538 |
|
| 2001 |
Porter AC, Felder CC. The endocannabinoid nervous system: Unique opportunities for therapeutic intervention Pharmacology and Therapeutics. 90: 45-60. PMID 11448725 DOI: 10.1016/S0163-7258(01)00130-9 |
0.462 |
|
| 2001 |
Felder CC, Porter AC, Skillman TL, Zhang L, Bymaster FP, Nathanson NM, Hamilton SE, Gomeza J, Wess J, McKinzie DL. Elucidating the role of muscarinic receptors in psychosis. Life Sciences. 68: 2605-13. PMID 11392633 DOI: 10.1016/S0024-3205(01)01059-1 |
0.534 |
|
| 2001 |
Salamone JD, Correa M, Carlson BB, Wisniecki A, Mayorga AJ, Nisenbaum E, Nisenbaum L, Felder C. Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents implications for cholinergic involvement in parkinsonism. Life Sciences. 68: 2579-84. PMID 11392629 DOI: 10.1016/S0024-3205(01)01055-4 |
0.39 |
|
| 2001 |
Bymaster FP, Carter PA, Zhang L, Falcone JF, Stengel PW, Cohen ML, Shannon HE, Gomeza J, Wess J, Felder CC. Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice. Life Sciences. 68: 2473-9. PMID 11392615 DOI: 10.1016/S0024-3205(01)01041-4 |
0.467 |
|
| 2001 |
Gomeza J, Zhang L, Kostenis E, Felder CC, Bymaster FP, Brodkin J, Shannon H, Xia B, Duttaroy A, Deng Cx, Wess J. Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice Life Sciences. 68: 2457-2466. PMID 11392613 DOI: 10.1016/S0024-3205(01)01039-6 |
0.571 |
|
| 2001 |
Yamada M, Miyakawa T, Duttaroy A, Yamanaka A, Moriguchi T, Makita R, Ogawa M, Chou CJ, Xia B, Crawley JN, Felder CC, Deng CX, Wess J. Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean. Nature. 410: 207-12. PMID 11242080 DOI: 10.1038/35065604 |
0.472 |
|
| 2001 |
Kennedy JS, Tune LE, Calligaro D, Bymaster FP, Felder CC, Verma S. The muscarinic (hm1-m5) and neuronal-nicotinic receptors binding profile of some medicines reported to have serum anticholinergic activity European Neuropsychopharmacology. 11. DOI: 10.1016/S0924-977X(01)80533-2 |
0.461 |
|
| 2000 |
Felder CC, Bymaster FP, Ward J, DeLapp N. Therapeutic opportunities for muscarinic receptors in the central nervous system. Journal of Medicinal Chemistry. 43: 4333-53. PMID 11087557 DOI: 10.1021/Jm990607U |
0.514 |
|
| 2000 |
Buckley NE, McCoy KL, Mezey E, Bonner T, Zimmer A, Felder CC, Glass M, Zimmer A. Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. European Journal of Pharmacology. 396: 141-9. PMID 10822068 DOI: 10.1016/S0014-2999(00)00211-9 |
0.529 |
|
| 1999 |
Gomeza J, Zhang L, Kostenis E, Felder C, Bymaster F, Brodkin J, Shannon H, Xia B, Deng C, Wess J. Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 10483-8. PMID 10468635 DOI: 10.1073/Pnas.96.18.10483 |
0.586 |
|
| 1999 |
Jeppesen L, Olesen PH, Hansen L, Sheardown MJ, Thomsen C, Rasmussen T, Jensen AF, Christensen MS, Rimvall K, Ward JS, Whitesitt C, Calligaro DO, Bymaster FP, Delapp NW, Felder CC, et al. 1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives. Journal of Medicinal Chemistry. 42: 1999-2006. PMID 10354408 DOI: 10.1021/Jm9910019 |
0.477 |
|
| 1999 |
Gomeza J, Shannon H, Kostenis E, Felder C, Zhang L, Brodkin J, Grinberg A, Sheng H, Wess J. Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 1692-7. PMID 9990086 DOI: 10.1073/Pnas.96.4.1692 |
0.56 |
|
| 1999 |
McKinzie JH, Sawyer BD, Felder CC, Falcone J, Silbernagel A, McClure D, DeLapp NW. An anti-G protein scintillation proximity assay for M1–M5 receptor-mediated GTPγS binding Life Sciences. 64: 570. DOI: 10.1016/S0024-3205(99)90495-2 |
0.418 |
|
| 1999 |
DeLapp NW, McClure D, McKinzie J, Silbernagel A, Sawyer BD, Felder CC. A study of M1 receptor coupling to inhibitory G proteins in CHO cells via GTPγS binding determined with anti-G protein antibodies Life Sciences. 64: 569. DOI: 10.1016/S0024-3205(99)90494-0 |
0.395 |
|
| 1999 |
Sawyer BD, Silbernagel A, McKinzie JB, Falcone J, Delapp N, Felder CC. Comparison of GTP-γ-35S and 3H-NMS binding in CHO cells stably expressing human M1–M5 muscarinic receptors using scintillation proximity assays Life Sciences. 64: 568. DOI: 10.1016/S0024-3205(99)90492-7 |
0.43 |
|
| 1999 |
Wood MW, Briley EM, Felder CC. Muscarinic receptor-activated arachidonic acid release is enhanced by cytokines in A2058 human melanoma cells Life Sciences. 64: 566. DOI: 10.1016/S0024-3205(99)90487-3 |
0.426 |
|
| 1998 |
Lautens LL, Chiou XG, Sharp JD, Young WS, Sprague DL, Ross LS, Felder CC. Cytosolic phospholipase A2 (cPLA2) distribution in murine brain and functional studies indicate that cPLA2 does not participate in muscarinic receptor-mediated signaling in neurons. Brain Research. 809: 18-30. PMID 9795110 DOI: 10.1016/S0006-8993(98)00806-3 |
0.48 |
|
| 1998 |
Felder CC, Glass M. Cannabinoid receptors and their endogenous agonists. Annual Review of Pharmacology and Toxicology. 38: 179-200. PMID 9597153 DOI: 10.1146/Annurev.Pharmtox.38.1.179 |
0.55 |
|
| 1998 |
Axelrod J, Felder CC. Cannabinoid receptors and their endogenous agonist, anandamide. Neurochemical Research. 23: 575-81. PMID 9566594 DOI: 10.1023/A:1022418217479 |
0.617 |
|
| 1998 |
Lamar TR, Lautens LL, Chiou XG, Sharp JD, Young WS, Sprague DL, Ross LS, Felder CC. 58 Cytosolic phospholipase A2 (cPLA2) distribution in murine brain and functional studies indicate that cPLA2 does not participate in muscarinic receptor-mediated signaling in neurons Journal of Physiology-Paris. 92: 454. DOI: 10.1016/S0928-4257(99)80070-9 |
0.395 |
|
| 1998 |
Felder CC, Joon JH, Briley EM, Wood MW. 32 Muscarinic receptor-activated arachidonic acid release is enhanced by cytokines in A2058 human melanoma cells Journal of Physiology-Paris. 92: 431. DOI: 10.1016/S0928-4257(99)80044-8 |
0.426 |
|
| 1997 |
Singer-Lahat D, Rojas E, Felder CC. A9 fibroblasts transfected with the m3 muscarinic receptor clone express a Ca2+ channel activated by carbachol, GTP and GDP. The Journal of Membrane Biology. 159: 21-8. PMID 9309207 DOI: 10.1007/S002329900265 |
0.394 |
|
| 1997 |
Glass M, Felder CC. Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Augments cAMP Accumulation in Striatal Neurons: Evidence for a Gs Linkage to the CB1 Receptor The Journal of Neuroscience. 17: 5327-5333. DOI: 10.1523/Jneurosci.17-14-05327.1997 |
0.545 |
|
| 1996 |
Singer-Lahat D, Rojas E, Felder CC. Muscarinic receptor activated Ca2+ channels in non-excitable cells. Progress in Brain Research. 109: 195-9. PMID 9009707 DOI: 10.1016/S0079-6123(08)62102-0 |
0.431 |
|
| 1996 |
Felder CC, Nielsen A, Briley EM, Palkovits M, Priller J, Axelrod J, Nguyen DN, Richardson JM, Riggin RM, Koppel GA, Paul SM, Becker GW. Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. Febs Letters. 393: 231-5. PMID 8814296 DOI: 10.1016/0014-5793(96)00891-5 |
0.545 |
|
| 1996 |
Kohn EC, Alessandro R, Probst J, Jacobs W, Brilley E, Felder CC. Identification and Molecular Characterization of a m5 Muscarinic Receptor in A2058 Human Melanoma Cells COUPLING TO INHIBITION OF ADENYLYL CYCLASE AND STIMULATION OF PHOSPHOLIPASE A2 Journal of Biological Chemistry. 271: 17476-17484. PMID 8663391 DOI: 10.1074/Jbc.271.29.17476 |
0.426 |
|
| 1996 |
Singer-Lahat D, Liu J, Wess J, Felder CC. The third intracellular domain of the m3 muscarinic receptor determines coupling to calcium influx in transfected Chinese hamster ovary cells. Febs Letters. 386: 51-4. PMID 8635603 DOI: 10.1016/0014-5793(96)00398-5 |
0.51 |
|
| 1996 |
Singer-Lahat D, Ma AL, Felder CC. Independent induction of morphological transformation of CHO cells by receptor-activated cyclic AMP synthesis or by receptor-operated calcium influx. Biochemical Pharmacology. 51: 495-502. PMID 8619896 DOI: 10.1016/0006-2952(95)02226-0 |
0.47 |
|
| 1995 |
Jose PA, Yu PY, Yamaguchi I, Eisner GM, Mouradian MM, Felder CC, Felder RA. Dopamine D1 receptor regulation of phospholipase C. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 18: S39-42. PMID 8529072 DOI: 10.1291/Hypres.18.Supplementi_S39 |
0.464 |
|
| 1995 |
Lolait SJ, O'Carroll AM, Mahan LC, Felder CC, Button DC, Young WS, Mezey E, Brownstein MJ. Extrapituitary expression of the rat V1b vasopressin receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 6783-7. PMID 7624319 DOI: 10.1073/Pnas.92.15.6783 |
0.536 |
|
| 1995 |
Garces Y, Briley EM, Felder CC. Vasopressin via receptor-stimulated phospholipase D: Differential regulation of transphosphatidylation and phospholipid hydrolysis by protein kinase C Neuropeptides. 28: 277-285. PMID 7603588 DOI: 10.1016/0143-4179(95)90044-6 |
0.366 |
|
| 1995 |
Felder CC. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. The Faseb Journal. 9: 619-625. DOI: 10.1096/Fasebj.9.8.7768353 |
0.534 |
|
| 1994 |
Briley EM, Lolait SJ, Axelrod J, Felder CC. The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels. Neuropeptides. 27: 63-74. PMID 7969820 DOI: 10.1016/0143-4179(94)90017-5 |
0.56 |
|
| 1994 |
Felder CC, Singer-Lahat D, Mathes C. Voltage-independent calcium channels: Regulation by receptors and intracellular calcium stores Biochemical Pharmacology. 48: 1997-2004. PMID 7802688 DOI: 10.1016/0006-2952(94)90498-7 |
0.323 |
|
| 1993 |
Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60. PMID 8395053 DOI: 10.1073/Pnas.90.16.7656 |
0.634 |
|
| 1993 |
Felder CC, Ma AL, Briley EM, Axelrod J. Muscarinic acetylcholine receptor subtypes associated with release of Alzheimer amyloid precursor derivatives activate multiple signal transduction pathways. Annals of the New York Academy of Sciences. 695: 15-8. PMID 8239275 DOI: 10.1111/J.1749-6632.1993.Tb23020.X |
0.65 |
|
| 1993 |
Nitsch RM, Slack BE, Farber SA, Borghesani PR, Schulz JG, Kim C, Felder CC, Growdon JH, Wurtman RJ. Receptor-coupled amyloid precursor protein processing. Annals of the New York Academy of Sciences. 695: 122-7. PMID 8239269 DOI: 10.1111/J.1749-6632.1993.Tb23039.X |
0.603 |
|
| 1993 |
Wisden W, Parker EM, Mahle CD, Grisel DA, Nowak HP, Yocca FD, Felder CC, Seeburg PH, Voigt MM. Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. Febs Letters. 333: 25-31. PMID 8224165 DOI: 10.1016/0014-5793(93)80368-5 |
0.496 |
|
| 1993 |
Crawley JN, Corwin RL, Robinson JK, Felder CC, Devane WA, Axelrod J. Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. Pharmacology, Biochemistry, and Behavior. 46: 967-72. PMID 7906042 DOI: 10.1016/0091-3057(93)90230-Q |
0.494 |
|
| 1993 |
Felder CC, MacArthur L, Ma AL, Gusovsky F, Kohn EC. Tumor-suppressor function of muscarinic acetylcholine receptors is associated with activation of receptor-operated calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 90: 1706-10. PMID 7680475 DOI: 10.1073/Pnas.90.5.1706 |
0.546 |
|
| 1993 |
Gusovsky F, Lueders J, Kohn E, Felder C. Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. An alternative mechanism for cholinergic-induced phosphoinositide breakdown. Journal of Biological Chemistry. 268: 7768-7772. DOI: 10.1016/s0021-9258(18)53024-6 |
0.321 |
|
| 1992 |
Felder CC, Poulter MO, Wess J. Muscarinic receptor-operated Ca2+ influx in transfected fibroblast cells is independent of inositol phosphates and release of intracellular Ca2+. Proceedings of the National Academy of Sciences of the United States of America. 89: 509-13. PMID 1731321 DOI: 10.1073/PNAS.89.2.509 |
0.364 |
|
| 1991 |
Voigt MM, McCune SK, Kanterman RY, Felder CC. The rat alpha 2-C4 adrenergic receptor gene encodes a novel pharmacological subtype. Febs Letters. 278: 45-50. PMID 1704314 DOI: 10.1016/0014-5793(91)80080-M |
0.443 |
|
| 1991 |
Felder CC, Williams HL, Axelrod J. A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release. Proceedings of the National Academy of Sciences of the United States of America. 88: 6477-80. PMID 1650470 DOI: 10.1073/Pnas.88.15.6477 |
0.623 |
|
| 1990 |
Felder CC, Kanterman RY, Ma AL, Axelrod J. Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 87: 2187-91. PMID 2315313 DOI: 10.1073/Pnas.87.6.2187 |
0.484 |
|
| 1990 |
Kanterman RY, Felder CC, Brenneman DE, Ma AL, Fitzgerald S, Axelrod J. Alpha 1-adrenergic receptor mediates arachidonic acid release in spinal cord neurons independent of inositol phospholipid turnover. Journal of Neurochemistry. 54: 1225-32. PMID 2156016 DOI: 10.1111/J.1471-4159.1990.Tb01952.X |
0.521 |
|
| 1990 |
Kanterman RY, Ma AL, Briley EM, Axelrod J, Felder CC. Muscarinic receptors mediate the release of arachidonic acid from spinal cord and hippocampal neurons in primary culture. Neuroscience Letters. 118: 235-7. PMID 2125713 DOI: 10.1016/0304-3940(90)90635-M |
0.583 |
|
| 1990 |
Jose PA, Felder RA, Felder CC, Chan W. Molecular biology of adrenergic and dopamine receptors and the study of developmental nephrology Pediatric Nephrology. 4: 679-685. PMID 1982417 DOI: 10.1007/Bf00858648 |
0.521 |
|
| 1990 |
Felder CC, Albrecht F, Eisner GM, Jose PA. The signal transducer for the dopamine-1 regulated sodium transport in renal cortical brush border membrane vesicles. American Journal of Hypertension. 3: 47S-50S. PMID 1974443 DOI: 10.1093/Ajh/3.6.47S |
0.326 |
|
| 1990 |
Cox JA, Felder CC, Henneberry RC. Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons. Neuron. 4: 941-947. PMID 1972886 DOI: 10.1016/0896-6273(90)90147-8 |
0.454 |
|
| 1989 |
Felder RA, Felder CC, Eisner GM, Jose PA. The dopamine receptor in adult and maturing kidney. American Journal of Physiology-Renal Physiology. 257. PMID 2571302 DOI: 10.1152/Ajprenal.1989.257.3.F315 |
0.342 |
|
| 1989 |
Felder CC, McKelvey AM, Gitler MS, Eisner GM, Jose PA. Dopamine receptor subtypes in renal brush border and basolateral membranes. Kidney International. 36: 183-93. PMID 2528652 DOI: 10.1038/Ki.1989.178 |
0.368 |
|
| 1989 |
Felder CC, Ma AL, Conklin BR. Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor. Febs Letters. 245: 75-9. PMID 2466702 DOI: 10.1016/0014-5793(89)80195-4 |
0.648 |
|
| 1987 |
McKelvey T, Felder C, Nakamura K, Robillard J, Jose P. MULTIPLE β -ADRENOCEPTORS ARE PRESENT IN ADULT BUT NOT FETAL SHEEP KIDNEYS Pediatric Research. 21: 218-218. DOI: 10.1203/00006450-198704010-00310 |
0.328 |
|
| 1985 |
Felder CC, Felder RA, Holloway RR, Robillard JE, Jose PA. 1592 Function Of Renal Dopamine-2 Receptors Pediatric Research. 19: 376-376. DOI: 10.1203/00006450-198504000-01616 |
0.336 |
|
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