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Michael A Funk - Publications

Affiliations: 
2017- AAAS 
Area:
biochemistry, structural biology, enzymology, microbiology
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80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Funk MA. Building niches for multiple microbes Science. 369: 1069-1071. DOI: 10.1126/Science.369.6507.1069-J  0.304
2020 Funk MA. Trio of enzymes power divergent synthesis Science. 369: 783-783. DOI: 10.1126/Science.369.6505.783-B  0.373
2020 Funk MA. Short path to a complex ring Science. 369: 639-641. DOI: 10.1126/Science.369.6504.639-S  0.356
2020 Funk MA. A stowaway in protein export Science. 369: 388-389. DOI: 10.1126/Science.369.6502.388-E  0.328
2020 Funk MA. Delicate dance becomes a ballet Science. 368: 1324-1324. DOI: 10.1126/Science.368.6497.1324-C  0.353
2020 Funk MA. Drug inhibition of glycosyltransferases Science. 368: 1201-1203. DOI: 10.1126/Science.368.6496.1201-L  0.363
2020 Funk MA. DNA barcodes in small packages Science. 368: 1076.18-1078. DOI: 10.1126/Science.368.6495.1076-R  0.305
2020 Funk MA. Fully synthetic whole proteins in reach Science. 368: 961.14-963. DOI: 10.1126/Science.368.6494.961-N  0.325
2020 Funk MA. Hybrid approach catches light Science. 368: 616.15-618. DOI: 10.1126/Science.368.6491.616-O  0.327
2020 Funk MA. Caught in the act Science. 368: 381-382. DOI: 10.1126/Science.368.6489.381-H  0.36
2020 Funk MA. Signs of a metabolon in action Science. 368: 278.10-280. DOI: 10.1126/Science.368.6488.278-J  0.387
2020 Funk MA. Microbes against microbial toxins Science. 368: 43.3-44. DOI: 10.1126/Science.368.6486.43-C  0.349
2020 Funk MA. Every twig and splinter used Science. 367: 1336.5-1337. DOI: 10.1126/Science.367.6484.1336-E  0.311
2020 Funk MA. Enzymes lock in planar chirality Science. 367: 864.17-866. DOI: 10.1126/Science.367.6480.864-Q  0.386
2020 Funk MA. Evolution of a kinase allosteric site Science. 367: 864.15-866. DOI: 10.1126/Science.367.6480.864-O  0.368
2020 Funk MA. A twisted small-molecule synthesis Science. 367: 401.6-402. DOI: 10.1126/Science.367.6476.401-F  0.339
2020 Funk MA. Electrostatics guide chromophore twist Science. 367: 36.17-38. DOI: 10.1126/Science.367.6473.36-Q  0.33
2019 Ting CP, Funk MA, Halaby SL, Zhang Z, Gonen T, van der Donk WA. Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products. Science (New York, N.Y.). 365: 280-284. PMID 31320540 DOI: 10.1126/Science.Aau6232  0.504
2019 Funk MA. Macrocycles made easy Science. 366: 1467.17-1469. DOI: 10.1126/Science.366.6472.1467-Q  0.367
2019 Funk MA. A division of labor for glycosylation Science. 366: 1324.16-1326. DOI: 10.1126/Science.366.6471.1324-P  0.42
2019 Funk MA. Maximal efficiency from enzyme cascades Science. 366: 1209.3-1209. DOI: 10.1126/Science.366.6470.1209-C  0.38
2019 Funk MA. Moving modules drive biosynthesis Science. 366: 702.10-704. DOI: 10.1126/Science.366.6466.702-J  0.407
2019 Funk MA. Itaconate brings metalloenzyme to a halt Science. 366: 583.13-585. DOI: 10.1126/Science.366.6465.583-M  0.382
2019 Funk MA. Parallel profiling of an enzyme family Science. 366: 441.7-442. DOI: 10.1126/Science.366.6464.441-G  0.334
2019 Funk MA. Dawn of methylotrophy Science. 366: 69.6-70. DOI: 10.1126/Science.366.6461.69-F  0.355
2019 Funk MA. Hemes switch spots in a terminal oxidase Science. 366: 68.15-70. DOI: 10.1126/Science.366.6461.68-O  0.432
2019 Funk MA. Distant cousin helps spot animal enzyme Science. 366: 68.14-70. DOI: 10.1126/Science.366.6461.68-N  0.347
2019 Funk MA. Conditions right for making nucleosides Science. 366: 68.9-70. DOI: 10.1126/Science.366.6461.68-I  0.345
2019 Funk MA. Active sites that move together Science. 365: 1131.14-1133. DOI: 10.1126/Science.365.6458.1131-N  0.41
2019 Funk MA. Double warhead does DNA damage Science. 365: 995.11-997. DOI: 10.1126/Science.365.6457.995-K  0.34
2019 Funk MA. Building psychoactives with purpose Science. 365: 879.4-880. DOI: 10.1126/Science.365.6456.879-D  0.344
2019 Funk MA. Innovations in an ATPase/ATP synthase Science. 365: 769.11-771. DOI: 10.1126/Science.365.6455.769-K  0.306
2019 Funk MA. Transition states under pressure Science. 365: 459.5-460. DOI: 10.1126/Science.365.6452.459-E  0.343
2019 Funk MA. A light-harvesting array in diatoms Science. 365: 458.10-460. DOI: 10.1126/Science.365.6452.458-J  0.306
2019 Funk MA. Predicting resource use in microbes Science. 365: 41.1-41. DOI: 10.1126/Science.365.6448.41-A  0.316
2019 Funk MA. Refilling the proton pump Science. 365: 40.4-40. DOI: 10.1126/Science.365.6448.40-D  0.321
2019 Funk MA. Light teaches (co)enzymes new tricks Science. 364: 1146.5-1147. DOI: 10.1126/Science.364.6446.1146-E  0.384
2019 Funk MA. ATP production under lockdown Science. 364: 1043.3-1043. DOI: 10.1126/Science.364.6445.1043-C  0.358
2019 Funk MA. Pathogen-sourced enzyme redirected Science. 364: 967.5-968. DOI: 10.1126/Science.364.6444.967-E  0.33
2019 Funk MA. Sweet spot for making oligosaccharides Science. 364: 645.14-647. DOI: 10.1126/Science.364.6441.645-N  0.356
2019 Funk MA. Dynamical refinement spots a difference Science. 364: 645.5-646. DOI: 10.1126/Science.364.6441.645-E  0.336
2019 Funk MA. How many metals to oxidize methane? Science. 364: 542.14-544. DOI: 10.1126/Science.364.6440.542-N  0.318
2019 Funk MA. The right bond in the right place Science. 364: 542.7-543. DOI: 10.1126/Science.364.6440.542-G  0.399
2019 Funk MA. Equal opportunity nitrogen sourcing Science. 363: 1188.1-1188. DOI: 10.1126/Science.363.6432.1188-A  0.33
2019 Funk MA. A wrench in the gears of life Science. 363: 494.11-496. DOI: 10.1126/Science.363.6426.494-K  0.366
2019 Funk MA. Plugging into the pump Science. 363: 241.3-241. DOI: 10.1126/Science.363.6424.241-C  0.334
2018 Orman M, Bodea S, Funk MA, Campo AM, Bollenbach M, Drennan CL, Balskus EP. Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Journal of the American Chemical Society. PMID 30557011 DOI: 10.2210/Pdb6Nd3/Pdb  0.513
2018 Chen PY, Funk MA, Brignole EJ, Drennan CL. Disruption of an oligomeric interface prevents allosteric inhibition of class Ia ribonucleotide reductase. The Journal of Biological Chemistry. PMID 29700111 DOI: 10.1074/Jbc.Ra118.002569  0.733
2018 Funk MA. A cage for catalysts Science. 362: 1260.3-1260. DOI: 10.1126/Science.362.6420.1260-C  0.386
2018 Funk MA. Evolution trains a from-scratch catalyst Science. 362: 1259.2-1259. DOI: 10.1126/Science.362.6420.1259-B  0.382
2018 Funk MA. An electron bridge in place of a ferry Science. 362: 1014.12-1016. DOI: 10.1126/Science.362.6418.1014-L  0.323
2018 Funk MA. Roadblocks removed by rapid evolution Science. 362: 789.6-790. DOI: 10.1126/Science.362.6416.789-F  0.375
2018 Funk MA. Light-powered cell factories Science. 362: 788.14-790. DOI: 10.1126/Science.362.6416.788-N  0.345
2018 Funk MA. How algae turn tides toxic Science. 361: 1350.6-1351. DOI: 10.1126/Science.361.6409.1350-F  0.349
2018 Funk MA. Specialized chaperones required Science. 361: 1084.7-1085. DOI: 10.1126/Science.361.6407.1084-G  0.347
2018 Funk MA. Metals brought together do more Science. 361: 1083.2-1083. DOI: 10.1126/Science.361.6407.1083-B  0.387
2018 Funk MA. Detection by protection Science. 361: 658.3-658. DOI: 10.1126/Science.361.6403.658-C  0.3
2018 Funk MA. Hack fracking for more methane Science. 361: 241.1-241. DOI: 10.1126/Science.361.6399.241-A  0.304
2018 Funk MA. Antenna switches partners in the shade Science. 360: 1082.13-1084. DOI: 10.1126/Science.360.6393.1082-M  0.303
2018 Funk MA. Something from nothing Science. 360: 871.6-872. DOI: 10.1126/Science.360.6391.871-F  0.371
2018 Vinson V, Funk MA. Protons find a path Science. 360: 615.11-617. DOI: 10.1126/Science.360.6389.615-K  0.334
2018 Funk MA. Double rings made with heme Science. 360: 44.12-46. DOI: 10.1126/Science.360.6384.44-L  0.408
2018 Funk MA. A scaffold for small proteins Science. 359: 1481.6-1482. DOI: 10.1126/Science.359.6383.1481-F  0.315
2018 Funk MA. A quick freeze shows an enzyme's secrets Science. 359: 1227.13-1229. DOI: 10.1126/Science.359.6381.1227-M  0.384
2018 Funk MA. A fitting way to finish Science. 359: 1005.6-1006. DOI: 10.1126/Science.359.6379.1005-F  0.362
2018 Funk MA. Remember the sugar when making proteins Science. 359: 530.5-531. DOI: 10.1126/Science.359.6375.530-E  0.399
2018 Funk MA. Fattening up proteins Science. 359: 172.16-174. DOI: 10.1126/Science.359.6372.172-P  0.388
2018 Funk MA. Ribosomes ignore the stop sign Science. 359: 44.7-45. DOI: 10.1126/Science.359.6371.44-G  0.364
2017 Backman LRF, Funk MA, Dawson CD, Drennan CL. New tricks for the glycyl radical enzyme family. Critical Reviews in Biochemistry and Molecular Biology. 1-22. PMID 28901199 DOI: 10.1080/10409238.2017.1373741  0.592
2017 Funk MA, van der Donk WA. Ribosomal Natural Products, Tailored To Fit. Accounts of Chemical Research. PMID 28682627 DOI: 10.1021/Acs.Accounts.7B00175  0.578
2017 Funk MA. An enzymatic route to alkenes Science. 358: 1144.2-1144. DOI: 10.1126/Science.358.6367.1144-B  0.408
2017 Funk MA. Watching SAM flip the switch Science. 358: 605.5-606. DOI: 10.1126/Science.358.6363.605-E  0.319
2016 Bodea S, Funk MA, Balskus EP, Drennan CL. Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell Chemical Biology. PMID 27642068 DOI: 10.1016/J.Chembiol.2016.07.020  0.603
2016 Oyala PH, Ravichandran KR, Funk MA, Stucky PA, Stich TA, Drennan CL, Britt RD, Stubbe J. Biophysical characterization of fluorotyrosine probes site-specifically incorporated into enzymes: E. coli ribonucleotide reductase as an example. Journal of the American Chemical Society. PMID 27276098 DOI: 10.1021/Jacs.6B03605  0.647
2016 Zimanyi CM, Chen PY, Kang G, Funk MA, Drennan CL. Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife. 5. PMID 26754917 DOI: 10.7554/Elife.07141  0.75
2015 Funk MA, Marsh EN, Drennan CL. Substrate-bound Structures of Benzylsuccinate Synthase Reveal How Toluene Is Activated in Anaerobic Hydrocarbon Degradation. The Journal of Biological Chemistry. 290: 22398-22408. PMID 26224635 DOI: 10.1074/Jbc.M115.670737  0.625
2014 Wei Y, Funk MA, Rosado LA, Baek J, Drennan CL, Stubbe J. The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant. Proceedings of the National Academy of Sciences of the United States of America. 111: E3756-65. PMID 25157154 DOI: 10.1073/Pnas.1414396111  0.641
2014 Funk MA, Judd ET, Marsh EN, Elliott SJ, Drennan CL. Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity. Proceedings of the National Academy of Sciences of the United States of America. 111: 10161-6. PMID 24982148 DOI: 10.1073/Pnas.1405983111  0.624
2011 Ando N, Brignole EJ, Zimanyi CM, Funk MA, Yokoyama K, Asturias FJ, Stubbe J, Drennan CL. Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. Proceedings of the National Academy of Sciences of the United States of America. 108: 21046-51. PMID 22160671 DOI: 10.1073/Pnas.1112715108  0.712
2010 Vey JL, Al-Mestarihi A, Hu Y, Funk MA, Bachmann BO, Iverson TM. Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis . Biochemistry. 49: 9306-17. PMID 20866105 DOI: 10.1021/Bi101336U  0.394
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