| Year |
Citation |
Score |
| 2018 |
Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, et al. Rapamycin-inspired macrocycles with new target specificity. Nature Chemistry. PMID 30532015 DOI: 10.1038/S41557-018-0187-4 |
0.319 |
|
| 2018 |
Kahlert V, Prell E, Ohlenschläger O, Melesina J, Schumann M, Lücke C, Fischer G, Malešević M. Synthesis and biochemical evaluation of two novel N-hydroxyalkylated cyclosporin A analogs. Organic and Biomolecular Chemistry. 16: 4338-4349. PMID 29845172 DOI: 10.1039/C8Ob00980E |
0.35 |
|
| 2018 |
Erdmann F, Prell E, Jahreis G, Fischer G, Malešević M. Screening for Selective Protein Inhibitors by Using the IANUS Peptide Array. Chembiochem. 19: 789-792. PMID 29411932 DOI: 10.1002/Cbic.201700652 |
0.359 |
|
| 2017 |
Stiegler SC, Rübbelke M, Korotkov VS, Weiwad M, John C, Fischer G, Sieber SA, Sattler M, Buchner J. A chemical compound inhibiting the Aha1-Hsp90 chaperone complex. The Journal of Biological Chemistry. PMID 28851842 DOI: 10.1074/Jbc.M117.797829 |
0.304 |
|
| 2017 |
Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, et al. The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells. Scientific Reports. 7: 613. PMID 28377614 DOI: 10.1038/S41598-017-00780-X |
0.341 |
|
| 2016 |
Lin W, Erdmann F, Quintero A, Fischer G, Zhang Y. Thioxylated cyclosporin A for studying protein-drug interactions. Bioorganic & Medicinal Chemistry Letters. PMID 27815116 DOI: 10.1016/J.Bmcl.2016.10.050 |
0.372 |
|
| 2016 |
Schumann M, Ihling CH, Prell E, Schierhorn A, Sinz A, Fischer G, Schiene-Fischer C, Malešević M. Identification of low abundance cyclophilins in human plasma Proteomics. 16: 2815-2826. PMID 27586231 DOI: 10.1002/Pmic.201600221 |
0.34 |
|
| 2015 |
Haslbeck V, Drazic A, Eckl JM, Alte F, Helmuth M, Popowicz G, Schmidt W, Braun F, Weiwad M, Fischer G, Gemmecker G, Sattler M, Striggow F, Groll M, Richter K. Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism. Bioscience Reports. 35. PMID 26182372 DOI: 10.1042/Bsr20150042 |
0.373 |
|
| 2014 |
Zierer BK, Weiwad M, Rübbelke M, Freiburger L, Fischer G, Lorenz OR, Sattler M, Richter K, Buchner J. Artificial accelerators of the molecular chaperone Hsp90 facilitate rate-limiting conformational transitions. Angewandte Chemie (International Ed. in English). 53: 12257-62. PMID 25244159 DOI: 10.1002/Anie.201406578 |
0.324 |
|
| 2013 |
Rentzsch A, Kahlert V, Jahreis G, Schlott B, Schutkowski M, Malešević M, Fischer G. Identification of prolyl oligopeptidase as a cyclosporine-sensitive protease by screening of mouse liver extracts. Biological Chemistry. 394: 1057-1067. PMID 23492557 DOI: 10.1515/Hsz-2013-0125 |
0.328 |
|
| 2013 |
Linnert M, Lin Y, Manns A, Haupt K, Paschke A, Fischer G, Weiwad M, Lücke C. The FKBP-type domain of the human aryl hydrocarbon receptor-interacting protein reveals an unusual Hsp90 interaction. Biochemistry. 52: 2097-2107. PMID 23418784 DOI: 10.1021/Bi301649M |
0.355 |
|
| 2013 |
Funkner A, Parthier C, Schutkowski M, Zerweck J, Lilie H, Gyrych N, Fischer G, Stubbs MT, Ferrari DM. Peptide binding by catalytic domains of the protein disulfide isomerase-related protein ERp46. Journal of Molecular Biology. 425: 1340-62. PMID 23376096 DOI: 10.1016/J.Jmb.2013.01.029 |
0.377 |
|
| 2013 |
Huang Y, Jahreis G, Lücke C, Fischer G. Rapid Nitrogen Inversion Pathway in the cis/trans Isomerization of Selenoxo Peptide Bonds Chemistry: a European Journal. 19: 1179-1183. PMID 23233128 DOI: 10.1002/Chem.201203721 |
0.393 |
|
| 2013 |
Prell E, Kahlert V, Rücknagel KP, Malešević M, Fischer G. Fine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue. Chembiochem. 14: 63-65. PMID 23225707 DOI: 10.1002/Cbic.201200621 |
0.326 |
|
| 2012 |
Hediger T, Frank W, Schumann M, Fischer G, Braun M. Aryl hetaryl ketones and thioketones as efficient inhibitors of peptidyl-prolyl cis-trans isomerases. Chemistry & Biodiversity. 9: 2618-34. PMID 23161639 DOI: 10.1002/Cbdv.201200275 |
0.336 |
|
| 2012 |
Malešević M, Schumann M, Jahreis G, Fischer G, Lücke C. Design of Cyclic Peptides Featuring Proline Predominantly in the cis Conformation under Physiological Conditions Chembiochem. 13: 2122-2127. PMID 22969011 DOI: 10.1002/Cbic.201200366 |
0.424 |
|
| 2012 |
Huang Y, Jahreis G, Fischer G, Lücke C. Atomic Polarizability Dominates the Electronic Properties of Peptide Bonds upon Thioxo or Selenoxo Substitution Chemistry: a European Journal. 18: 9841-9848. PMID 22782859 DOI: 10.1002/Chem.201200863 |
0.34 |
|
| 2012 |
Kunz C, Jahreis G, Günther R, Berger S, Fischer G, Hofmann HJ. Influence of lithium cations on prolyl peptide bonds. Journal of Peptide Science : An Official Publication of the European Peptide Society. 18: 400-4. PMID 22522384 DOI: 10.1002/Psc.2410 |
0.384 |
|
| 2012 |
Kaiser E, Böhm N, Ernst K, Langer S, Schwan C, Aktories K, Popoff M, Fischer G, Barth H. FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells. Cellular Microbiology. 14: 1193-205. PMID 22420783 DOI: 10.1111/J.1462-5822.2012.01788.X |
0.373 |
|
| 2012 |
Linnert M, Haupt K, Lin Y, Kissing S, Paschke A, Fischer G, Weiwad M, Lücke C. NMR assignments of the FKBP-type PPIase domain of the human aryl-hydrocarbon receptor-interacting protein (AIP). Biomolecular Nmr Assignments. 6: 209-212. PMID 22287093 DOI: 10.1007/S12104-012-9359-0 |
0.338 |
|
| 2011 |
Banasavadi-Siddegowda YK, Mai J, Fan Y, Bhattacharya S, Giovannucci DR, Sanchez ER, Fischer G, Wang X. FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulum. The Journal of Biological Chemistry. 286: 43071-80. PMID 22030396 DOI: 10.1074/Jbc.M111.269993 |
0.356 |
|
| 2011 |
Schumann M, Jahreis G, Kahlert V, Lücke C, Fischer G. Oligopeptide cyclophilin inhibitors: A reassessment European Journal of Medicinal Chemistry. 46: 5556-5561. PMID 21963115 DOI: 10.1016/J.Ejmech.2011.09.019 |
0.438 |
|
| 2011 |
Norville IH, Harmer NJ, Harding SV, Fischer G, Keith KE, Brown KA, Sarkar-Tyson M, Titball RW. A Burkholderia pseudomallei macrophage infectivity potentiator-like protein has rapamycin-inhibitable peptidylprolyl isomerase activity and pleiotropic effects on virulence. Infection and Immunity. 79: 4299-307. PMID 21859853 DOI: 10.1128/Iai.00134-11 |
0.355 |
|
| 2011 |
Ãœnal C, Schwedhelm KF, Thiele A, Weiwad M, Schweimer K, Frese F, Fischer G, Hacker J, Faber C, Steinert M. Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration. Cellular Microbiology. 13: 1558-72. PMID 21794054 DOI: 10.1111/J.1462-5822.2011.01641.X |
0.385 |
|
| 2011 |
Kaiser E, Kroll C, Ernst K, Schwan C, Popoff M, Fischer G, Buchner J, Aktories K, Barth H. Membrane translocation of binary actin-ADP-ribosylating toxins from Clostridium difficile and Clostridium perfringens is facilitated by cyclophilin A and Hsp90. Infection and Immunity. 79: 3913-21. PMID 21768281 DOI: 10.1128/Iai.05372-11 |
0.304 |
|
| 2011 |
Thiele A, Krentzlin K, Erdmann F, Rauh D, Hause G, Zerweck J, Kilka S, Pösel S, Fischer G, Schutkowski M, Weiwad M. Parvulin 17 promotes microtubule assembly by its peptidyl-prolyl cis/trans isomerase activity. Journal of Molecular Biology. 411: 896-909. PMID 21756916 DOI: 10.1016/J.Jmb.2011.06.040 |
0.347 |
|
| 2011 |
Schiene-Fischer C, Aumüller T, Fischer G. Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins Topics in Current Chemistry. 328: 35-67. PMID 21598101 DOI: 10.1007/128_2011_151 |
0.449 |
|
| 2011 |
Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M, Braun M, Fischer G, Zhang K, Liu JO. A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. The Journal of Pharmacology and Experimental Therapeutics. 338: 466-75. PMID 21562139 DOI: 10.1124/Jpet.111.180851 |
0.302 |
|
| 2011 |
Theuerkorn M, Fischer G, Schiene-Fischer C. Prolyl cis/trans isomerase signalling pathways in cancer☆ Current Opinion in Pharmacology. 11: 281-287. PMID 21497135 DOI: 10.1016/J.Coph.2011.03.007 |
0.402 |
|
| 2011 |
Bachmann A, Wildemann D, Praetorius F, Fischer G, Kiefhaber T. Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction Proceedings of the National Academy of Sciences of the United States of America. 108: 3952-3957. PMID 21325613 DOI: 10.1073/Pnas.1012668108 |
0.651 |
|
| 2011 |
Dmochewitz L, Lillich M, Kaiser E, Jennings LD, Lang AE, Buchner J, Fischer G, Aktories K, Collier RJ, Barth H. Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen. Cellular Microbiology. 13: 359-73. PMID 20946244 DOI: 10.1111/J.1462-5822.2010.01539.X |
0.323 |
|
| 2011 |
Maestre-Martínez M, Haupt K, Edlich F, Neumann P, Parthier C, Stubbs MT, Fischer G, Lücke C. A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding. Journal of Molecular Recognition : Jmr. 24: 23-34. PMID 20140889 DOI: 10.1002/Jmr.1020 |
0.315 |
|
| 2010 |
Thiele A, Weiwad M, Zerweck J, Fischer G, Schutkowski M. High density peptide microarrays for proteome-wide fingerprinting of kinase activities in cell lysates. Methods in Molecular Biology (Clifton, N.J.). 669: 173-81. PMID 20857366 DOI: 10.1007/978-1-60761-845-4_14 |
0.391 |
|
| 2010 |
Malesević M, Poehlmann A, Hernandez Alvarez B, Diessner A, Träger M, Rahfeld JU, Jahreis G, Liebscher S, Bordusa F, Fischer G, Lücke C. The protein-free IANUS peptide array uncovers interaction sites between Escherichia coli parvulin 10 and alkyl hydroperoxide reductase. Biochemistry. 49: 8626-35. PMID 20806779 DOI: 10.1021/Bi101015P |
0.411 |
|
| 2010 |
Maestre-Martínez M, Haupt K, Edlich F, Jahreis G, Jarczowski F, Erdmann F, Fischer G, Lücke C. New structural aspects of FKBP38 activation. Biological Chemistry. 391: 1157-1167. PMID 20707607 DOI: 10.1515/Bc.2010.122 |
0.353 |
|
| 2010 |
Huang Y, Jahreis G, Lücke C, Wildemann D, Fischer G. Modulation of the peptide backbone conformation by the selenoxo photoswitch. Journal of the American Chemical Society. 132: 7578-7579. PMID 20481495 DOI: 10.1021/Ja1019386 |
0.367 |
|
| 2010 |
Aumüller T, Jahreis G, Fischer G, Schiene-Fischer C. Role of prolyl cis/trans isomers in cyclophilin-assisted Pseudomonas syringae AvrRpt2 protease activation. Biochemistry. 49: 1042-1052. PMID 20050698 DOI: 10.1021/Bi901813E |
0.383 |
|
| 2010 |
Malesević M, Kühling J, Erdmann F, Balsley MA, Bukrinsky MI, Constant SL, Fischer G. A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins. Angewandte Chemie (International Ed. in English). 49: 213-5. PMID 19957254 DOI: 10.1002/Anie.200904529 |
0.396 |
|
| 2010 |
Erdmann F, Weiwad M, Kilka S, Karanik M, Pätzel M, Baumgrass R, Liebscher J, Fischer G. The Novel Calcineurin Inhibitor CN585 Has Potent Immunosuppressive Properties in Stimulated Human T Cells Journal of Biological Chemistry. 285: 1888-1898. PMID 19923214 DOI: 10.1074/Jbc.M109.024844 |
0.33 |
|
| 2009 |
Zoldák G, Aumüller T, Lücke C, Hritz J, Oostenbrink C, Fischer G, Schmid FX. A library of fluorescent peptides for exploring the substrate specificities of prolyl isomerases Biochemistry. 48: 10423-10436. PMID 19785464 DOI: 10.1021/Bi9014242 |
0.591 |
|
| 2009 |
Thiele A, Zerweck J, Weiwad M, Fischer G, Schutkowski M. High-density peptide microarrays for reliable identification of phosphorylation sites and upstream kinases. Methods in Molecular Biology (Clifton, N.J.). 570: 203-19. PMID 19649595 DOI: 10.1007/978-1-60327-394-7_9 |
0.365 |
|
| 2009 |
Uhlenbrock K, Weiwad M, Wetzker R, Fischer G, Wittinghofer A, Rubio I. Reassessment of the role of FKBP38 in the Rheb/mTORC1 pathway. Febs Letters. 583: 965-70. PMID 19222999 DOI: 10.1016/J.Febslet.2009.02.015 |
0.34 |
|
| 2009 |
Kilka S, Erdmann F, Migdoll A, Fischer G, Weiwad M. The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding. Biochemistry. 48: 1900-1910. PMID 19154138 DOI: 10.1021/Bi8019355 |
0.324 |
|
| 2009 |
Barak NN, Neumann P, Sevvana M, Schutkowski M, Naumann K, Malesevi? M, Reichardt H, Fischer G, Stubbs MT, Ferrari DM. Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29. Journal of Molecular Biology. 385: 1630-42. PMID 19084538 DOI: 10.1016/J.Jmb.2008.11.052 |
0.406 |
|
| 2009 |
Jarczowski F, Jahreis G, Erdmann F, Schierhorn A, Fischer G, Edlich F. FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor. Journal of Biological Chemistry. 284: 766-773. PMID 19001379 DOI: 10.1074/Jbc.M709779200 |
0.366 |
|
| 2008 |
Jarczowski F, Fischer G, Edlich F. FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes. Biochemistry. 47: 6946-6952. PMID 18529014 DOI: 10.1021/Bi8001506 |
0.352 |
|
| 2008 |
Reiner A, Wildemann D, Fischer G, Kiefhaber T. Effect of thioxopeptide bonds on alpha-helix structure and stability. Journal of the American Chemical Society. 130: 8079-84. PMID 18512914 DOI: 10.1021/Ja8015044 |
0.63 |
|
| 2008 |
Braun M, Hessamian-Alinejad A, de Lacroix BF, Alvarez BH, Fischer G. Novel spiroannulated 3-benzofuranones. Synthesis and inhibition of the human peptidyl prolyl cis/trans isomerase Pin1. Molecules (Basel, Switzerland). 13: 995-1003. PMID 18463601 DOI: 10.3390/Molecules13040995 |
0.344 |
|
| 2008 |
Aumüller T, Fischer G. Bioactivity of folding intermediates studied by the recovery of enzymatic activity during refolding. Journal of Molecular Biology. 376: 1478-1492. PMID 18234226 DOI: 10.1016/J.Jmb.2007.12.057 |
0.423 |
|
| 2008 |
Malešević M, Jahreis G, Wawra S, Fischer G, Lücke C. Conformational Consequences of Regio-and Stereoselective Disulfide Bridge Oxidation in a Cyclic Peptide Chembiochem. 9: 46-49. PMID 18072227 DOI: 10.1002/Cbic.200700529 |
0.321 |
|
| 2007 |
Edlich F, Maestre-Martínez M, Jarczowski F, Weiwad M, Moutty M, Malešević M, Jahreis G, Fischer G, Lücke C. A Novel Calmodulin-Ca2+ Target Recognition Activates the Bcl-2 Regulator FKBP38 Journal of Biological Chemistry. 282: 36496-36504. PMID 17942410 DOI: 10.1074/Jbc.M705061200 |
0.31 |
|
| 2007 |
Wildemann D, Hernandez Alvarez B, Stoller G, Zhou XZ, Lu KP, Erdmann F, Ferrari D, Fischer G. An essential role for Pin1 in Xenopus laevis embryonic development revealed by specific inhibitors. Biological Chemistry. 388: 1103-11. PMID 17937625 DOI: 10.1515/Bc.2007.127 |
0.324 |
|
| 2007 |
Sieber M, Karanik M, Brandt C, Blex C, Podtschaske M, Erdmann F, Rost R, Serfling E, Liebscher J, Pätzel M, Radbruch A, Fischer G, Baumgrass R. Inhibition of calcineurin-NFAT signaling by the pyrazolopyrimidine compound NCI3. European Journal of Immunology. 37: 2617-2626. PMID 17694572 DOI: 10.1002/Eji.200737087 |
0.316 |
|
| 2007 |
Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lücke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chemical Biology. 2: 320-8. PMID 17518432 DOI: 10.1021/Cb7000044 |
0.394 |
|
| 2007 |
Wildemann D, Schiene-Fischer C, Aumüller T, Bachmann A, Kiefhaber T, Lücke C, Fischer G. A nearly isosteric photosensitive amide-backbone substitution allows enzyme activity switching in ribonuclease S Journal of the American Chemical Society. 129: 4910-4918. PMID 17397159 DOI: 10.1021/Ja069048O |
0.649 |
|
| 2007 |
Wagner C, Khan AS, Kamphausen T, Schmausser B, Unal C, Lorenz U, Fischer G, Hacker J, Steinert M. Collagen binding protein Mip enables Legionella pneumophila to transmigrate through a barrier of NCI-H292 lung epithelial cells and extracellular matrix. Cellular Microbiology. 9: 450-62. PMID 16953800 DOI: 10.1111/J.1462-5822.2006.00802.X |
0.34 |
|
| 2007 |
Siegrist R, Zürcher M, Baumgartner C, Seiler P, Diederich F, Daum S, Fischer G, Klein C, Dangl M, Schwaiger M. A novel synthesis of highly substituted perhydropyrrolizines, perhydroindolizines, and pyrrolidines: Inhibition of the peptidyl-prolyl cis/trans isomerase (PPIase) Pin1 Helvetica Chimica Acta. 90: 217-259. DOI: 10.1002/Hlca.200790028 |
0.375 |
|
| 2006 |
Weiwad M, Edlich F, Kilka S, Erdmann F, Jarczowski F, Dorn M, Moutty M, Fischer G. Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins. Biochemistry. 45: 15776-15784. PMID 17176100 DOI: 10.1021/Bi061616P |
0.356 |
|
| 2006 |
Daum S, Erdmann F, Fischer G, Féaux de Lacroix B, Hessamian-Alinejad A, Houben S, Frank W, Braun M. Aryl indanyl ketones: efficient inhibitors of the human peptidyl prolyl cis/trans isomerase Pin1. Angewandte Chemie (International Ed. in English). 45: 7454-8. PMID 17048295 DOI: 10.1002/Anie.200601569 |
0.34 |
|
| 2006 |
Horstmann M, Ehses P, Schweimer K, Steinert M, Kamphausen T, Fischer G, Hacker J, Rösch P, Faber C. Domain motions of the Mip protein from Legionella pneumophila. Biochemistry. 45: 12303-11. PMID 17014083 DOI: 10.1021/Bi060818I |
0.313 |
|
| 2006 |
Fischer G, Wawra S. Polypeptide binding proteins: what remains to be discovered? Molecular Microbiology. 61: 1388-1396. PMID 16930150 DOI: 10.1111/J.1365-2958.2006.05349.X |
0.448 |
|
| 2006 |
Fanghänel J, Wawra S, Lücke C, Wildemann D, Fischer G. Isothermal calorimetry as a tool to investigate slow conformational changes in proteins and peptides Analytical Chemistry. 78: 4517-4523. PMID 16808461 DOI: 10.1021/Ac052040X |
0.39 |
|
| 2006 |
Edlich F, Fischer G. Pharmacological targeting of catalyzed protein folding: the example of peptide bond cis/trans isomerases. Handbook of Experimental Pharmacology. 359-404. PMID 16610367 DOI: 10.1007/3-540-29717-0_15 |
0.351 |
|
| 2006 |
Wildemann D, Erdmann F, Alvarez BH, Stoller G, Zhou XZ, Fanghänel J, Schutkowski M, Lu KP, Fischer G. Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries. Journal of Medicinal Chemistry. 49: 2147-50. PMID 16570909 DOI: 10.1021/Jm060036N |
0.374 |
|
| 2006 |
Edlich F, Weiwad M, Wildemann D, Jarczowski F, Kilka S, Moutty MC, Jahreis G, Lücke C, Schmidt W, Striggow F, Fischer G. The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia. The Journal of Biological Chemistry. 281: 14961-70. PMID 16547004 DOI: 10.1074/Jbc.M600452200 |
0.313 |
|
| 2006 |
Fischer G. Enzymes Catalyzing Peptide Bond Cis-Trans Isomerizations Cis-Trans Isomerization in Biochemistry. 195-224. DOI: 10.1002/9783527609338.ch10 |
0.302 |
|
| 2005 |
Leuzzi R, Serino L, Scarselli M, Savino S, Fontana MR, Monaci E, Taddei A, Fischer G, Rappuoli R, Pizza M. Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages. Molecular Microbiology. 58: 669-81. PMID 16238618 DOI: 10.1111/J.1365-2958.2005.04859.X |
0.33 |
|
| 2005 |
Eckerdt F, Yuan J, Saxena K, Martin B, Kappel S, Lindenau C, Kramer A, Naumann S, Daum S, Fischer G, Dikic I, Kaufmann M, Strebhardt K. Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. The Journal of Biological Chemistry. 280: 36575-83. PMID 16118204 DOI: 10.1074/Jbc.M504548200 |
0.33 |
|
| 2005 |
Edlich F, Weiwad M, Erdmann F, Fanghänel J, Jarczowski F, Rahfeld J, Fischer G. Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin The Embo Journal. 24: 2688-2699. PMID 15990872 DOI: 10.1038/Sj.Emboj.7600739 |
0.303 |
|
| 2005 |
Kim C, Gajendran N, Mittrücker H, Weiwad M, Song Y, Hurwitz R, Wilmanns M, Fischer G, Kaufmann SHE. Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences. Proceedings of the National Academy of Sciences of the United States of America. 102: 4830-4835. PMID 15772169 DOI: 10.1073/Pnas.0500508102 |
0.314 |
|
| 2005 |
Weiwad M, Edlich F, Erdmann F, Jarczowski F, Kilka S, Dorn M, Pechstein A, Fischer G. A reassessment of the inhibitory capacity of human FKBP38 on calcineurin. Febs Letters. 579: 1591-1596. PMID 15757646 DOI: 10.1016/J.Febslet.2004.12.098 |
0.352 |
|
| 2005 |
Yu C, Malesevic M, Jahreis G, Schutkowski M, Fischer G, Schiene‐Fischer C. The architecture of protein-ligand binding sites revealed through template-assisted intramolecular peptide-peptide interactions. Angewandte Chemie. 44: 1408-1412. PMID 15666425 DOI: 10.1002/Anie.200460991 |
0.36 |
|
| 2005 |
Zhang Y, Erdmann F, Baumgrass R, Schutkowski M, Fischer G. Unexpected Side Chain Effects at Residue 8 of Cyclosporin A Derivatives Allow Photoswitching of Immunosuppression Journal of Biological Chemistry. 280: 4842-4850. PMID 15572368 DOI: 10.1074/Jbc.M409178200 |
0.351 |
|
| 2005 |
Watanabe S, Tsuruoka S, Vijayakumar S, Fischer G, Zhang Y, Fujimura A, Al-Awqati Q, Schwartz GJ. Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin. American Journal of Physiology. Renal Physiology. 288: F40-7. PMID 15353404 DOI: 10.1152/Ajprenal.00218.2004 |
0.31 |
|
| 2004 |
Fanghänel J, Fischer G. Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases. Frontiers in Bioscience. 9: 3453-3478. PMID 15353370 DOI: 10.2741/1494 |
0.376 |
|
| 2004 |
Kühlewein A, Voll G, Alvarez BH, Kessler H, Fischer G, Rahfeld J, Gemmecker G. Solution structure of Escherichia coli Par10: The prototypic member of the Parvulin family of peptidyl‐prolyl cis/trans isomerases Protein Science. 13: 2378-2387. PMID 15322281 DOI: 10.1110/Ps.04756704 |
0.415 |
|
| 2004 |
Manteca A, Kamphausen T, Fanghanel J, Fischer G, Sanchez J. Cloning and characterization of a Streptomyces antibioticus ATCC11891 cyclophilin related to Gram negative bacteria cyclophilins. Febs Letters. 572: 19-26. PMID 15304318 DOI: 10.1016/J.Febslet.2004.06.091 |
0.309 |
|
| 2004 |
Weiwad M, Werner A, Rücknagel P, Schierhorn A, Küllertz G, Fischer G. Catalysis of proline-directed protein phosphorylation by peptidyl-prolyl cis/trans isomerases. Journal of Molecular Biology. 339: 635-646. PMID 15147846 DOI: 10.1016/J.Jmb.2004.04.021 |
0.407 |
|
| 2004 |
Dubourg B, Kamphausen T, Weiwad M, Jahreis G, Feunteun J, Fischer G, Modjtahedi N. The Human Nuclear SRcyp Is a Cell Cycle-regulated Cyclophilin Journal of Biological Chemistry. 279: 22322-22330. PMID 15016823 DOI: 10.1074/Jbc.M400736200 |
0.31 |
|
| 2003 |
Brecht S, Schwarze K, Waetzig V, Christner C, Heiland S, Fischer G, Sartor K, Herdegen T. Changes in peptidyl-prolyl cis/trans isomerase activity and fk506 binding protein expression following neuroprotection by fk506 in the ischemic rat brain Neuroscience. 120: 1037-1048. PMID 12927209 DOI: 10.1016/S0306-4522(03)00404-4 |
0.3 |
|
| 2003 |
Köhler R, Fanghänel J, König B, Lüneberg E, Frosch M, Rahfeld JU, Hilgenfeld R, Fischer G, Hacker J, Steinert M. Biochemical and functional analyses of the Mip protein: influence of the N-terminal half and of peptidylprolyl isomerase activity on the virulence of Legionella pneumophila. Infection and Immunity. 71: 4389-97. PMID 12874317 DOI: 10.1128/Iai.71.8.4389-4397.2003 |
0.389 |
|
| 2003 |
Reimer T, Weiwad M, Schierhorn A, Ruecknagel P, Rahfeld J, Bayer P, Fischer G. Phosphorylation of the N-terminal Domain Regulates Subcellular Localization and DNA Binding Properties of the Peptidyl-prolyl cis/trans Isomerase hPar14 Journal of Molecular Biology. 330: 955-966. PMID 12860119 DOI: 10.1016/S0022-2836(03)00713-7 |
0.354 |
|
| 2003 |
Fischer G, Aumüller T. Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes Reviews of Physiology Biochemistry and Pharmacology. 148: 105-150. PMID 12698322 DOI: 10.1007/S10254-003-0011-3 |
0.463 |
|
| 2003 |
Helbig JH, König B, Knospe H, Bubert B, Yu C, Lück CP, Riboldi-Tunnicliffe A, Hilgenfeld R, Jacobs E, Hacker J, Fischer G. The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells. Biological Chemistry. 384: 125-37. PMID 12674506 DOI: 10.1515/Bc.2003.013 |
0.384 |
|
| 2003 |
Blaha G, Wilson DN, Stoller G, Fischer G, Willumeit R, Nierhaus KH. Localization of the trigger factor binding site on the ribosomal 50 S subunit Journal of Molecular Biology. 326: 887-897. PMID 12581648 DOI: 10.1016/S0022-2836(02)01436-5 |
0.331 |
|
| 2003 |
Kuhlewein A, Voll G, Schelbert B, Kessler H, Fischer G, Rahfeld J, Gemmecker G. Solution Structure of the Peptidyl-Prolyl-cis/trans-Isomerase Parvulin 10 of Escherichia coli Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5225 |
0.323 |
|
| 2002 |
Fanghänel J, Fischer G. Thermodynamic characterization of the interaction of human cyclophilin 18 with cyclosporin A Biophysical Chemistry. 100: 351-366. PMID 12646377 DOI: 10.1016/S0301-4622(02)00292-2 |
0.307 |
|
| 2002 |
Schiene-Fischer C, Habazettl J, Tradler T, Fischer G. Evaluation of similarities in the cis/trans isomerase function of trigger factor and DnaK. Biological Chemistry. 383: 1865-1873. PMID 12553723 DOI: 10.1515/Bc.2002.210 |
0.474 |
|
| 2002 |
Zhang Y, Füssel S, Reimer U, Schutkowski M, Fischer G. Substrate-based design of reversible Pin1 inhibitors. Biochemistry. 41: 11868-11877. PMID 12269831 DOI: 10.1021/Bi0262395 |
0.387 |
|
| 2002 |
Cavarec L, Kamphausen T, Dubourg B, Callebaut I, Lemeunier F, Métivier D, Feunteun J, Fischer G, Modjtahedi N. Identification and characterization of Moca-cyp. A Drosophila melanogaster nuclear cyclophilin. The Journal of Biological Chemistry. 277: 41171-82. PMID 12154086 DOI: 10.1074/Jbc.M203757200 |
0.39 |
|
| 2002 |
Surmacz TA, Bayer E, Rahfeld JU, Fischer G, Bayer P. The N-terminal Basic Domain of Human Parvulin hPar14 is Responsible for the Entry to the Nucleus and High-affinity DNA-binding Journal of Molecular Biology. 321: 235-247. PMID 12144781 DOI: 10.1016/S0022-2836(02)00615-0 |
0.342 |
|
| 2002 |
Reimer U, Fischer G. Local structural changes caused by peptidyl–prolyl cis/trans isomerization in the native state of proteins Biophysical Chemistry. 96: 203-212. PMID 12034441 DOI: 10.1016/S0301-4622(02)00013-3 |
0.374 |
|
| 2002 |
Schiene-Fischer C, Habazettl J, Schmid FX, Fischer G. The hsp70 chaperone DnaK is a secondary amide peptide bond cis-trans isomerase. Nature Structural Biology. 9: 419-24. PMID 12021775 DOI: 10.1038/Nsb804 |
0.63 |
|
| 2001 |
Riboldi-Tunnicliffe A, König B, Jessen S, Weiss MS, Rahfeld J, Hacker J, Fischer G, Hilgenfeld R. Crystal structure of Mip, a prolylisomerase from Legionella pneumophila. Nature Structural Biology. 8: 779-83. PMID 11524681 DOI: 10.1038/Nsb0901-779 |
0.347 |
|
| 2001 |
Schiene-Fischer C, Fischer G. Direct Measurement Indicates a Slow Cis/Trans Isomerization at the Secondary Amide Peptide Bond of Glycylglycine Journal of the American Chemical Society. 123: 6227-6231. PMID 11427045 DOI: 10.1021/Ja0042480 |
0.434 |
|
| 2001 |
Pappenberger G, Aygün H, Engels JW, Reimer U, Fischer G, Kiefhaber T. Nonprolyl cis peptide bonds in unfolded proteins cause complex folding kinetics Nature Structural Biology. 8: 452-458. PMID 11323723 DOI: 10.1038/87624 |
0.668 |
|
| 2001 |
Metzner M, Stoller G, Rücknagel KP, Lu KP, Fischer G, Luckner M, Küllertz G. Functional Replacement of the Essential ESS1 in Yeast by the Plant Parvulin DlPar13 Journal of Biological Chemistry. 276: 13524-13529. PMID 11118437 DOI: 10.1074/Jbc.M007005200 |
0.363 |
|
| 2000 |
Zhou XZ, Kops O, Werner A, Lu PJ, Shen M, Stoller G, Küllertz G, Stark M, Fischer G, Lu KP. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Molecular Cell. 6: 873-883. PMID 11090625 DOI: 10.1016/S1097-2765(05)00083-3 |
0.421 |
|
| 2000 |
Sekerina E, Rahfeld JU, Müller J, Fanghänel J, Rascher C, Fischer G, Bayer P. NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein. Journal of Molecular Biology. 301: 1003-1017. PMID 10966801 DOI: 10.1006/Jmbi.2000.4013 |
0.425 |
|
| 2000 |
Weiwad M, Küllertz G, Schutkowski M, Fischer G. Evidence that the substrate backbone conformation is critical to phosphorylation by p42 MAP kinase Febs Letters. 478: 39-42. PMID 10922466 DOI: 10.1016/S0014-5793(00)01794-4 |
0.423 |
|
| 2000 |
Schiene C, Fischer G. Enzymes that catalyse the restructuring of proteins. Current Opinion in Structural Biology. 10: 40-45. PMID 10679456 DOI: 10.1016/S0959-440X(99)00046-9 |
0.386 |
|
| 2000 |
Santos AN, Körber S, Küllertz G, Fischer G, Fischer B. Oxygen stress increases prolyl cis/trans isomerase activity and expression of cyclophilin 18 in rabbit blastocysts. Biology of Reproduction. 62: 1-7. PMID 10611060 DOI: 10.1095/Biolreprod62.1.1 |
0.33 |
|
| 2000 |
Fischer G. Chemical aspects of peptide bond isomerisation Chemical Society Reviews. 29: 119-127. DOI: 10.1039/A803742F |
0.408 |
|
| 1999 |
Brandsch M, Knütter I, Thunecke F, Hartrodt B, Born I, Börner V, Hirche F, Fischer G, Neubert K. Decisive structural determinants for the interaction of proline derivatives with the intestinal H+/peptide symporter Febs Journal. 266: 502-508. PMID 10561591 DOI: 10.1046/J.1432-1327.1999.00885.X |
0.444 |
|
| 1999 |
Christner C, Wyrwa R, Marsch S, Küllertz G, Thiericke R, Grabley S, Schumann D, Fischer G. Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties. Journal of Medicinal Chemistry. 42: 3615-3622. PMID 10479292 DOI: 10.1021/Jm991038T |
0.327 |
|
| 1999 |
Golbik R, Fischer G, Fersht AR. Folding of barstar C40A/C82A/P27A and catalysis of the peptidyl-prolyl cis/trans isomerization by human cytosolic cyclophilin (Cyp18). Protein Science. 8: 1505-1514. PMID 10422840 DOI: 10.1110/Ps.8.7.1505 |
0.346 |
|
| 1999 |
Teter SA, Houry WA, Ang D, Tradler T, Rockabrand D, Fischer G, Blum P, Georgopoulos C, Hartl FU. Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. Cell. 97: 755-65. PMID 10380927 DOI: 10.1016/S0092-8674(00)80787-4 |
0.315 |
|
| 1999 |
Uchida T, Fujimori F, Tradler T, Fischer G, Rahfeld J. Identification and characterization of a 14 kDa human protein as a novel parvulin-like peptidyl prolyl cis/trans isomerase Febs Letters. 446: 278-282. PMID 10100858 DOI: 10.1016/S0014-5793(99)00239-2 |
0.408 |
|
| 1999 |
Wildemann D, Drewello M, Fischer G, Schutkowski M. Extremely selective Mg(ClO4)2 mediated removal of Bpoc/Ddz moieties suitable for the solid phase peptide synthesis of thioxo peptides Chemical Communications. 1809-1810. DOI: 10.1039/A905678E |
0.313 |
|
| 1998 |
Kops O, Eckerskorn C, Hottenrott S, Fischer G, Mi H, Tropschug M. Ssp1, a site-specific parvulin homolog from Neurospora crassa active in protein folding. The Journal of Biological Chemistry. 273: 31971-6. PMID 9822668 DOI: 10.1074/Jbc.273.48.31971 |
0.471 |
|
| 1998 |
Schiene C, Reimer U, Schutkowski M, Fischer G. Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases. Febs Letters. 432: 202-206. PMID 9720925 DOI: 10.1016/S0014-5793(98)00871-0 |
0.431 |
|
| 1998 |
Reimer U, Scherer G, Drewello M, Kruber S, Schutkowski M, Fischer G. Side-Chain Effects On Peptidyl-Prolyl Cis/Trans Isomerisation Journal of Molecular Biology. 279: 449-460. PMID 9642049 DOI: 10.1006/Jmbi.1998.1770 |
0.445 |
|
| 1998 |
Fischer G, Tradler T, Zarnt T. The mode of action of peptidyl prolyl cis/trans isomerases in vivo: binding vs. catalysis. Febs Letters. 426: 17-20. PMID 9598969 DOI: 10.1016/S0014-5793(98)00242-7 |
0.41 |
|
| 1998 |
Scholz C, Scherer G, Mayr LM, Schindler T, Fischer G, Schmid FX. Prolyl isomerases do not catalyze isomerization of non-prolyl peptide bonds Biological Chemistry. 379: 361-365. PMID 9563833 |
0.568 |
|
| 1998 |
Hennig L, Christner C, Kipping M, Schelbert B, Rücknagel KP, Grabley S, Küllertz G, Fischer G. Selective Inactivation Of Parvulin-Like Peptidyl-Prolyl Cis/Trans Isomerases By Juglone Biochemistry. 37: 5953-5960. PMID 9558330 DOI: 10.1021/Bi973162P |
0.401 |
|
| 1998 |
Schutkowski M, Bernhardt A, Zhou XZ, Shen M, Reimer U, Rahfeld J, Lu KP, Fischer G. Role Of Phosphorylation In Determining The Backbone Dynamics Of The Serine/ Threonine-Proline Motif And Pin1 Substrate Recognition Biochemistry. 37: 5566-5575. PMID 9548941 DOI: 10.1021/Bi973060Z |
0.405 |
|
| 1998 |
Thunecke F, Fischer G. Separation of cis/trans conformers of human and salmon calcitonin by low temperature capillary electrophoresis Electrophoresis. 19: 288-294. PMID 9548293 DOI: 10.1002/Elps.1150190224 |
0.388 |
|
| 1998 |
Lopez-Ilasaca M, Schiene C, Küllertz G, Tradler T, Fischer G, Wetzker R. Effects of FK506-binding Protein 12 and FK506 on Autophosphorylation of Epidermal Growth Factor Receptor Journal of Biological Chemistry. 273: 9430-9434. PMID 9545268 DOI: 10.1074/Jbc.273.16.9430 |
0.304 |
|
| 1998 |
Brandsch M, Thunecke F, Küllertz G, Schutkowski M, Fischer G, Neubert K. Evidence for the Absolute Conformational Specificity of the Intestinal H+/Peptide Symporter, PEPT1 Journal of Biological Chemistry. 273: 3861-3864. PMID 9461567 DOI: 10.1074/Jbc.273.7.3861 |
0.407 |
|
| 1998 |
Küllertz G, Lüthe S, Fischer G. Semiautomated microtiter plate assay for monitoring peptidylprolyl cis/trans isomerase activity in normal and pathological human sera Clinical Chemistry. 44: 502-508. DOI: 10.1093/Clinchem/44.3.502 |
0.328 |
|
| 1998 |
Scherer G, Kramer ML, Schutkowski M, Reimer U, Fischer G. Barriers to rotation of secondary amide peptide bonds Journal of the American Chemical Society. 120: 5568-5574. DOI: 10.1021/Ja980181T |
0.416 |
|
| 1998 |
Keller M, Sager C, Dumy P, Schutkowski M, Fischer GS, Mutter M. Enhancing the proline effect: Pseudo-prolines for tailoring Cis/ trans isomerization Journal of the American Chemical Society. 120: 2714-2720. DOI: 10.1021/Ja973966S |
0.435 |
|
| 1997 |
Yaffe MB, Schutkowski M, Shen M, Zhou XZ, Stukenberg PT, Rahfeld JU, Xu J, Kuang J, Kirschner MW, Fischer G, Cantley LC, Lu KP. Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science (New York, N.Y.). 278: 1957-60. PMID 9395400 DOI: 10.1126/Science.278.5345.1957 |
0.363 |
|
| 1997 |
Reimer U, Mokdad NE, Schutkowski M, Fischer G. Intramolecular assistance of cis/trans isomerization of the histidine-proline moiety. Biochemistry. 36: 13802-13808. PMID 9374856 DOI: 10.1021/Bi9713916 |
0.417 |
|
| 1997 |
Scholz C, Rahfeld J, Fischer G, Schmid FX. Catalysis of protein folding by Parvulin Journal of Molecular Biology. 273: 752-762. PMID 9356262 DOI: 10.1006/Jmbi.1997.1301 |
0.601 |
|
| 1997 |
Janowski B, Wöllner S, Schutkowski M, Fischer G. A protease-free assay for peptidyl prolyl cis/trans isomerases using standard peptide substrates. Analytical Biochemistry. 252: 299-307. PMID 9344417 DOI: 10.1006/Abio.1997.2330 |
0.464 |
|
| 1997 |
Reimer U, Drewello M, Jakob M, Fischer G, Schutkowski M. Conformational state of a 25-mer peptide from the cyclophilin-binding loop of the HIV type 1 capsid protein. Biochemical Journal. 326: 181-185. PMID 9337866 DOI: 10.1042/Bj3260181 |
0.374 |
|
| 1997 |
Zarnt T, Tradler T, Stoller G, Scholz C, Schmid FX, Fischer G. Modular structure of the trigger factor required for high activity in protein folding Journal of Molecular Biology. 271: 827-837. PMID 9299330 DOI: 10.1006/Jmbi.1997.1206 |
0.576 |
|
| 1997 |
Hottenrott S, Schumann T, Plückthun A, Fischer G, Rahfeld JU. The Escherichia coli SlyD is a metal ion-regulated peptidyl-prolyl cis/trans-isomerase. The Journal of Biological Chemistry. 272: 15697-701. PMID 9188461 DOI: 10.1074/Jbc.272.25.15697 |
0.405 |
|
| 1997 |
Tradler T, Stoller G, Rücknagel KP, Schierhorn A, Rahfeld J, Fischer G. Comparative mutational analysis of peptidyl prolyl cis/trans isomerases: active sites of Escherichia coli trigger factor and human FKBP12. Febs Letters. 407: 184-190. PMID 9166896 DOI: 10.1016/S0014-5793(97)00345-1 |
0.403 |
|
| 1997 |
Schutkowski M, Jakob M, Landgraf G, Born I, Neubert K, Fischer G. Probing substrate backbone function in prolyl oligopeptidase catalysis--large positional effects of peptide bond monothioxylation. European Journal of Biochemistry / Febs. 245: 381-5. PMID 9151967 DOI: 10.1111/J.1432-1033.1997.00381.X |
0.418 |
|
| 1997 |
Janowski B, Fischer G. Modulation of cyclosporin A/cyclophilin interactions by drug vehicles Bioorganic & Medicinal Chemistry. 5: 179-186. PMID 9043669 DOI: 10.1016/S0968-0896(96)00198-8 |
0.397 |
|
| 1997 |
Zhao Y, Chen Y, Schutkowski M, Fischer G, Ke H. Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity. Structure. 5: 139-146. PMID 9016720 DOI: 10.1016/S0969-2126(97)00172-X |
0.391 |
|
| 1997 |
Scholz C, Stoller G, Zarnt T, Fischer G, Schmid FX. Cooperation of enzymatic and chaperone functions of trigger factor in the catalysis of protein folding Embo Journal. 16: 54-58. PMID 9009267 DOI: 10.1093/Emboj/16.1.54 |
0.595 |
|
| 1997 |
Schmidt B, Tradler T, Rahfeld JU, Ludwig B, Jain B, Mann K, Rücknagel KP, Janowski B, Schierhorn A, Küllertz G, Hacker J, Fischer G. A cyclophilin-like peptidyl-prolyl cis/trans isomerase from Legionella pneumophila--characterization, molecular cloning and overexpression. Molecular Microbiology. 21: 1147-60. PMID 8898384 DOI: 10.1046/J.1365-2958.1996.00061.X |
0.386 |
|
| 1997 |
Kramer ML, Fischer G. FKBP-like catalysis of peptidyl-prolyl bond isomerization by micelles and membranes Biopolymers. 42: 49-60. DOI: 10.1002/(Sici)1097-0282(199707)42:1<49::Aid-Bip5>3.0.Co;2-1 |
0.447 |
|
| 1997 |
Pfeifer T, Schierhorn A, Friedemann R, Jakob M, Frank R, Schutkowski M, Fischer G. Specific fragmentation of thioxo peptides facilitates the assignment of the thioxylated amino acid Journal of Mass Spectrometry. 32: 1064-1071. DOI: 10.1002/(Sici)1096-9888(199711)32:10<1064::Aid-Jms560>3.0.Co;2-7 |
0.308 |
|
| 1996 |
Schutkowski M, Drewello M, Wöllner S, Jakob M, Reimer U, Scherer G, Schierhorn A, Fischer G. Extended binding sites of cyclophilin as revealed by the interaction with HIV-1 Gag polyprotein derived oligopeptides Febs Letters. 394: 289-294. PMID 8830660 DOI: 10.1016/0014-5793(96)00972-6 |
0.34 |
|
| 1996 |
Rahfeld J, Rücknagel KP, Stoller G, Horne SM, Schierhorn A, Young KD, Fischer G. Isolation and amino acid sequence of a new 22-kDa FKBP-like peptidyl-prolyl cis/trans-isomerase of Escherichia coli. Similarity to Mip-like proteins of pathogenic bacteria. Journal of Biological Chemistry. 271: 22130-22138. PMID 8703024 DOI: 10.1074/Jbc.271.36.22130 |
0.386 |
|
| 1996 |
Scholz C, Zarnt T, Kern G, Lang K, Burtscher H, Fischer G, Schmid FX. Autocatalytic folding of the folding catalyst FKBP12 Journal of Biological Chemistry. 271: 12703-12707. PMID 8662669 DOI: 10.1074/Jbc.271.22.12703 |
0.612 |
|
| 1996 |
Stoller G, Tradler T, Rücknagel KP, Rahfeld J, Fischer G. An 11.8 kDa proteolytic fragment of the E. coli trigger factor represents the domain carrying the peptidyl-prolyl cis/trans isomerase activity Febs Letters. 384: 117-122. PMID 8612805 DOI: 10.1016/0014-5793(96)00282-7 |
0.385 |
|
| 1996 |
Meyer S, Drewello M, Fischer G. Influence of helix formation on cis/trans isomerism of Xaa-Pro bonds flanking the helical segment. Biological Chemistry. 377: 489-495. DOI: 10.1515/Bchm3.1996.377.7-8.489 |
0.42 |
|
| 1995 |
Kern G, Kern D, Schmid FX, Fischer G. A kinetic analysis of the folding of human carbonic anhydrase II and its catalysis by cyclophilin Journal of Biological Chemistry. 270: 740-745. PMID 7822304 DOI: 10.1074/Jbc.270.2.740 |
0.693 |
|
| 1995 |
Wintermeyer E, Ludwig B, Steinert M, Schmidt B, Fischer G, Hacker J. Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infection and Immunity. 63: 4576-4583. PMID 7591108 DOI: 10.1128/Iai.63.12.4576-4583.1995 |
0.333 |
|
| 1995 |
Stoller G, Rücknagel KP, Nierhaus KH, Schmid FX, Fischer G, Rahfeld JU. A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor Embo Journal. 14: 4939-4948. PMID 7588623 |
0.532 |
|
| 1995 |
Kern D, Kern G, Scherer G, Fischer G, Drakenberg T. Kinetic analysis of cyclophilin-catalyzed prolyl cis/trans isomerization by dynamic NMR spectroscopy Biochemistry. 34: 13594-13602. PMID 7577948 DOI: 10.1021/Bi00041A039 |
0.608 |
|
| 1995 |
Schmidt B, König S, Svergun D, Volkov V, Fischer G, Koch MHJ. Small-angle X-ray solution scattering study on the dimerization of the FKBP25mem from Legionella pneumophila Febs Letters. 372: 169-172. PMID 7556662 DOI: 10.1016/0014-5793(95)00951-5 |
0.317 |
|
| 1995 |
Schutkowski M, Wöllner S, Fischer G. Inhibition of peptidyl-prolyl cis/trans isomerase activity by substrate analog structures: thioxo tetrapeptide-4-nitroanilides. Biochemistry. 34: 13016-26. PMID 7548060 DOI: 10.1021/BI00040A012 |
0.335 |
|
| 1995 |
Zarnt T, Lang K, Burtscher H, Fischer G. Time-dependent inhibition of peptidylprolyl cis-trans-isomerases by FK506 is probably due to cis-trans isomerization of the inhibitor's imide bond Biochemical Journal. 305: 159-164. PMID 7529995 DOI: 10.1042/Bj3050159 |
0.447 |
|
| 1995 |
Stoller G, Rücknagel KP, Nierhaus KH, Schmid FX, Fischer G, Rahfeld JU. A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor. The Embo Journal. 14: 4939-4948. DOI: 10.1002/J.1460-2075.1995.Tb00177.X |
0.581 |
|
| 1994 |
Rahfeld J, Rücknagel KP, Schelbert B, Ludwig B, Hacker J, Mann K, Fischer G. Confirmation of the existence of a third family among peptidyl-prolyl cis/trans isomerases Amino acid sequence and recombinant production of parvulin Febs Letters. 352: 180-184. PMID 7925971 DOI: 10.1016/0014-5793(94)00932-5 |
0.413 |
|
| 1994 |
Kern G, Kern D, Schmid FX, Fischer G. Reassessment of the putative chaperone function of prolyl-cis/trans-isomerases Febs Letters. 348: 145-148. PMID 7913447 DOI: 10.1016/0014-5793(94)00591-5 |
0.669 |
|
| 1994 |
Schutkowski M, Neubert K, Fischer G. Influence on proline-specific enzymes of a substrate containing the thioxoaminoacyl–prolyl peptide bond Febs Journal. 221: 455-461. PMID 7909521 DOI: 10.1111/J.1432-1033.1994.Tb18758.X |
0.401 |
|
| 1994 |
Meyer S, Jabs A, Schutkowski M, Fischer G. Separation of cis/trans isomers of a prolyl peptide bond by capillary zone electrophoresis Electrophoresis. 15: 1151-1157. PMID 7859723 DOI: 10.1002/Elps.11501501174 |
0.396 |
|
| 1994 |
Küllertz G, Meyer S, Fischer G. Differentiation by preparative continuous free flow-isoelectric focusing of cyclosporin A inhibitable peptidyl-prolyl cis/trans isomerase of human erythrocytes. Electrophoresis. 15: 960-967. PMID 7813402 DOI: 10.1002/Elps.11501501140 |
0.375 |
|
| 1994 |
Schmidt B, Rahfeld J, Schierhorn A, Ludwig B, Hacker J, Fischer G. A homodimer represents an active species of the peptidyl-prolyl cis/trans isomerase FKBP25mem from Legionella pneumophila. Febs Letters. 352: 185-190. PMID 7523184 DOI: 10.1016/0014-5793(94)00970-8 |
0.398 |
|
| 1994 |
Ludwig B, Rahfeld J, Schmidt B, Mann K, Wintermeyer E, Fischer G, Hacker J. Characterization of Mip proteins of Legionella pneumophila Fems Microbiology Letters. 118: 23-30. PMID 7516906 DOI: 10.1111/J.1574-6968.1994.Tb06798.X |
0.38 |
|
| 1994 |
Fischer G. Peptidyl-prolyl cis/trans isomerases and their effectors Angewandte Chemie. 33: 1415-1436. DOI: 10.1002/Anie.199414151 |
0.336 |
|
| 1994 |
Fischer G. Über Peptidyl‐Prolyl‐cis/trans‐Isomerasen und ihre Effektoren Angewandte Chemie. 106: 1479-1501. DOI: 10.1002/Ange.19941061404 |
0.342 |
|
| 1993 |
Kern D, Drakenberg T, Wikström M, Forsén S, Bang H, Fischer G. The cis/trans interconversion of the calcium regulating hormone calcitonin is catalyzed by cyclophilin Febs Letters. 323: 198-202. PMID 8500610 DOI: 10.1016/0014-5793(93)81338-Z |
0.611 |
|
| 1993 |
Hacker J, Ott M, Wintermeyer E, Ludwig B, Fischer G. Analysis of virulence factors of Legionella pneumophila. Zentralblatt Fur Bakteriologie-International Journal of Medical Microbiology Virology Parasitology and Infectious Diseases. 278: 348-358. PMID 8347938 DOI: 10.1016/S0934-8840(11)80851-0 |
0.31 |
|
| 1993 |
Hacker J, Fischer G. Immunophilins: structure-function relationship and possible role in microbial pathogenicity. Molecular Microbiology. 10: 445-456. PMID 7526121 DOI: 10.1111/J.1365-2958.1993.Tb00917.X |
0.42 |
|
| 1992 |
Herrler M, Bang H, Brune K, Fischer G, Marahiel MA. Peptidyl-prolyl cis-trans isomerase from Bacillus subtilis. A prokaryotic enzyme that is highly sensitive to cyclosporin A. Febs Letters. 309: 231-234. PMID 1516692 DOI: 10.1016/0014-5793(92)80779-G |
0.444 |
|
| 1992 |
Fischer G, Bang H, Ludwig B, Mann K, Hacker J. Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity. Molecular Microbiology. 6: 1375-1383. PMID 1379319 DOI: 10.1111/J.1365-2958.1992.Tb00858.X |
0.451 |
|
| 1991 |
Hübner D, Drakenberg T, Forsén S, Fischer G. Peptidyl-prolyl cis-trans isomerase activity as studied by dynamic proton NMR spectroscopy. Febs Letters. 284: 79-81. PMID 2060630 DOI: 10.1016/0014-5793(91)80766-V |
0.326 |
|
| 1991 |
Hübner D, Hartrodt B, Kleinpeter E, Ströhl D, Brandt W, Schinke H, Wahab M, Fischer G. Conformational analysis of the tetrapeptide Pro-D-Phe-Pro-Gly in aqueous solution. Biochemical and Biophysical Research Communications. 177: 271-278. PMID 2043113 DOI: 10.1016/0006-291X(91)91978-L |
0.395 |
|
| 1990 |
Fischer G, Schmid FX. The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell. Biochemistry. 29: 2205-12. PMID 2186809 DOI: 10.1021/Bi00461A001 |
0.542 |
|
| 1989 |
Fischer G, Berger E, Bang H. Kinetic β‐deuterium isotope effects suggest a covalent mechanism for the protein folding enzyme peptidylprolyl cis/trans‐isomerase Febs Letters. 250: 267-270. PMID 2666157 DOI: 10.1016/0014-5793(89)80735-5 |
0.378 |
|
| 1989 |
Fischer G, Wittmann-Liebold B, Lang K, Kiefhaber T, Schmid FX. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature. 337: 476-8. PMID 2492638 DOI: 10.1038/337476A0 |
0.75 |
|
| 1988 |
Flatau S, Fischer G, Kleinpeter E, Schellenberger A. 31P NMR investigations on free and enzyme bound thiamine pyrophosphate Febs Letters. 233: 379-382. PMID 3289972 DOI: 10.1016/0014-5793(88)80465-4 |
0.583 |
|
| 1988 |
Demuth HU, Baumgrass R, Schaper C, Fischer G, Barth A. Dipeptidylpeptidase IV--inactivation with N-peptidyl-O-aroyl hydroxylamines. Journal of Enzyme Inhibition. 2: 129-142. PMID 2906996 DOI: 10.3109/14756368809040718 |
0.354 |
|
| 1987 |
Lang K, Schmid FX, Fischer G. Catalysis of protein folding by prolyl isomerase. Nature. 329: 268-70. PMID 3306408 DOI: 10.1038/329268A0 |
0.626 |
|
| 1985 |
Fischer G, Bang H. The refolding of urea-denatured ribonuclease A is catalyzed by peptidyl-prolyl cis-trans isomerase Biochimica Et Biophysica Acta. 828: 39-42. PMID 3882150 DOI: 10.1016/0167-4838(85)90006-8 |
0.392 |
|
| 1984 |
Fischer G, Bang H, Berger E, Schellenberger A. Conformational specificity of chymotrypsin toward proline-containing substrates Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 791: 87-97. PMID 6498206 DOI: 10.1016/0167-4838(84)90285-1 |
0.654 |
|
| 1983 |
Fischer G, Heins J, Barth A. The conformation around the peptide bond between the P1- and P2-positions is important for catalytic activity of some proline-specific proteases. Biochimica Et Biophysica Acta. 742: 452-462. PMID 6340741 DOI: 10.1016/0167-4838(83)90261-3 |
0.435 |
|
| 1982 |
Fischer G, Sieber M, Schellenberger A. The carbonyl reactivity of 3-bromopyruvate and related compounds Bioorganic Chemistry. 11: 478-484. DOI: 10.1016/0045-2068(82)90039-6 |
0.544 |
|
| 1978 |
Fischer G, Jatzkewitz H. The activator of cerebroside-sulphatase. A model of the activation. Biochimica Et Biophysica Acta. 528: 69-76. PMID 23173 DOI: 10.1016/0005-2760(78)90053-X |
0.315 |
|
| 1977 |
Fischer G, Jatzkewitz H. The activator of cerebroside sulphatase. Binding studies with enzyme and substrate demonstrating the detergent function of the activator protein. Biochimica Et Biophysica Acta. 481: 561-72. PMID 15613 DOI: 10.1016/0005-2744(77)90288-1 |
0.374 |
|
| 1976 |
Fischer G, Küllertz G, Schellenberger A. Zur theorie der α-ketosäuren. Sekundäre thermodynamische und kinetische deuterium isotopieeffekte bie nucleophilen additionsreaktionen an die α-carbonyl-gruppe von pyruvamid Tetrahedron. 32: 1503-1505. DOI: 10.1016/0040-4020(76)85204-0 |
0.56 |
|
| 1975 |
Huebner G, Neef H, Fischer G, Schellenberger A. Kinetischer (15)N-Isotopieeffekt Als Direkter Beweis Fuer Die Unmittelbare Beteiligung Der Aminogruppe Von Thiaminpyrophosphat An Der Enzymatischen Decarboxylierung Von Alpha-Ketosaeuren Durch Hefe-Pyruvatdecarboxylase Cheminform. 6. DOI: 10.1002/Chin.197537421 |
0.697 |
|
| 1973 |
Lehmann H, Fischer G, Hübner G, Kohnert KD, Schellenberger A. The influence of steric and electronic parameters on the substrate behavior of -oxo acids to yeast pyruvate decarboxylase. European Journal of Biochemistry. 32: 83-87. PMID 4687392 DOI: 10.1111/J.1432-1033.1973.Tb02582.X |
0.589 |
|
| 1972 |
Fischer G, Oehme G, Schellenberger A. Theorie Der Alpha-Ketosaeuren 19. Mitt. Beziehungen Zwischen Struktur Und Uv-Spektren Von Alpha-Ketosaeuren Und Verwandten Alpha-Dicarbonylverbindungen Cheminform. 3. DOI: 10.1002/Chin.197210088 |
0.51 |
|
| 1971 |
Fischer G, Oehme G, Schellenberger A. Zur theorie der α-ketosäuren. Beziehungen zwischen struktur und UV-Spektren von α-ketosäuren und verwandten α-dicarbonylverbindungen Tetrahedron. 27: 5683-5696. DOI: 10.1016/S0040-4020(01)91733-8 |
0.533 |
|
| 1967 |
Oehme G, Fischer G, Schellenberger A. Zur Theorie der α‐Ketosäuren, XV. IR‐Spektroskopische Untersuchungen der Stereochemie und Energieübertragung in intramolekularen Wasserstoffbrücken substituierter Phenylglyoxylsäuren Chemische Berichte. 100: 425-437. DOI: 10.1002/Cber.19671000209 |
0.531 |
|
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