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Ying Lu, ph.D - Publications

Affiliations: 
2000-2004 Physics Peking University, China, Beijing, Beijing Shi, China 
 2004-2010 Biophysics Rockefeller University, New York, NY, United States 
 2010-2016 Systems Biology Harvard Medical School, Boston, MA, United States 
 2016- Systems Biology Harvard Medical School, Boston, MA, United States 
Area:
Ubiquitin-mediated protein degradation
Website:
https://yinglu.hms.harvard.edu/research
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhou M, Fang R, Colson L, Donovan KA, Hunkeler M, Song Y, Zhang C, Chen S, Lee DH, Bradshaw GA, Eisert R, Ye Y, Kalocsay M, Goldberg A, Fischer ES, ... Lu Y, et al. HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates. Biorxiv : the Preprint Server For Biology. PMID 37398461 DOI: 10.1101/2023.05.30.542866  0.658
2022 Fang R, Hon J, Zhou M, Lu Y. An empirical energy landscape reveals mechanism of proteasome in polypeptide translocation. Elife. 11. PMID 35050852 DOI: 10.7554/eLife.71911  0.642
2020 Zhao Y, Wang D, Zhang Z, Lu Y, Yang X, Ouyang Q, Tang C, Li F. Critical slowing down and attractive manifold: A mechanism for dynamic robustness in the yeast cell-cycle process. Physical Review. E. 101: 042405. PMID 32422801 DOI: 10.1103/Physreve.101.042405  0.321
2019 Hon J, Lu Y. Single-molecule methods for measuring ubiquitination and protein stability. Methods in Enzymology. 619: 225-247. PMID 30910022 DOI: 10.1016/Bs.Mie.2018.12.031  0.375
2018 Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y. Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature. PMID 30479383 DOI: 10.1038/S41586-018-0736-4  0.368
2018 Zhu Y, Wang WL, Yu D, Ouyang Q, Lu Y, Mao Y. Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nature Communications. 9: 1360. PMID 29636472 DOI: 10.1038/S41467-018-03785-W  0.351
2017 Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y. Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Molecular Cell. PMID 28689658 DOI: 10.1016/J.Molcel.2017.06.007  0.476
2017 Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, et al. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discovery. PMID 28174173 DOI: 10.1158/2159-8290.Cd-16-0647  0.517
2016 Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y. Structural basis for dynamic regulation of the human 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791164 DOI: 10.1073/Pnas.1614614113  0.512
2016 Brown NG, VanderLinden R, Watson ER, Weissmann F, Ordureau A, Wu KP, Zhang W, Yu S, Mercredi PY, Harrison JS, Davidson IF, Qiao R, Lu Y, Dube P, Brunner MR, et al. Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell. 165: 1440-1453. PMID 27259151 DOI: 10.1016/J.Cell.2016.05.037  0.504
2016 Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D. USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites. Nature. PMID 27074503 DOI: 10.1038/Nature17433  0.585
2015 Lu Y, Lee BH, King RW, Finley D, Kirschner MW. Substrate degradation by the proteasome: a single-molecule kinetic analysis. Science (New York, N.Y.). 348: 1250834. PMID 25859050 DOI: 10.1126/Science.1250834  0.629
2015 Lu Y, Wang W, Kirschner MW. Specificity of the anaphase-promoting complex: a single-molecule study. Science (New York, N.Y.). 348: 1248737. PMID 25859049 DOI: 10.1126/Science.1248737  0.502
2013 Fukushima H, Ogura K, Wan L, Lu Y, Li V, Gao D, Liu P, Lau AW, Wu T, Kirschner MW, Inuzuka H, Wei W. SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression. Cell Reports. 4: 803-16. PMID 23972993 DOI: 10.1016/J.Celrep.2013.07.031  0.636
2010 Lu Y, Cross FR. Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator. Cell. 141: 268-79. PMID 20403323 DOI: 10.1016/J.Cell.2010.03.021  0.563
2009 Drapkin BJ, Lu Y, Procko AL, Timney BL, Cross FR. Analysis of the mitotic exit control system using locked levels of stable mitotic cyclin. Molecular Systems Biology. 5: 328. PMID 19920813 DOI: 10.1038/Msb.2009.78  0.56
2009 Lu Y, Cross F. Mitotic exit in the absence of separase activity. Molecular Biology of the Cell. 20: 1576-91. PMID 19144818 DOI: 10.1091/Mbc.E08-10-1042  0.555
2009 Lu Y, Cross F. Cdc14-release Oscillation is Separable from Cell-cycle Progression, and Modulated by Clb-Cdk Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1515  0.558
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