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Stuart Maudsley, PhD - Publications

Affiliations: 
1997-2000 Lefkowitz Lab Duke University / HHMI 
 2000-2004 Human Reproductive Sciences Unit Medical Research Council 
 2000-2004 Center for Reproductive Biology University of Edinburgh, Edinburgh, Scotland, United Kingdom 
 2004-2014 Receptor Pharmacology Unit National Institute on Aging, Baltimore, MD, United States 
 2012-2014 Biochemistry and Molecular Biology Johns Hopkins Bloomberg School of Public Health 
 2012-2014 Department of Endocrinology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2014- Receptor Biology Lab University of Antwerp, Antwerpen, Vlaanderen, Belgium 
Area:
G protein-coupled receptors, Molecular Pharmacology, Proteomics, Bioinformatics, Molecular Gerontology
Website:
https://www.researchgate.net/profile/Stuart_Maudsley
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Year Citation  Score
2020 Hendrickx JO, van Gastel J, Leysen H, Martin B, Maudsley S. High-dimensionality Data Analysis of Pharmacological Systems Associated with Complex Diseases. Pharmacological Reviews. 72: 191-217. PMID 31843941 DOI: 10.1124/Pr.119.017921  0.782
2019 Santos-Otte P, Leysen H, van Gastel J, Hendrickx JO, Martin B, Maudsley S. G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence. Computational and Structural Biotechnology Journal. 17: 1265-1277. PMID 31921393 DOI: 10.1016/J.Csbj.2019.08.005  0.823
2019 van Gastel J, Leysen H, Santos-Otte P, Hendrickx JO, Azmi A, Martin B, Maudsley S. The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. Aging. 11. PMID 31794429 DOI: 10.18632/aging.102528  0.796
2019 Van Gastel J, Cai H, Cong WN, Chadwick W, Daimon C, Leysen H, Hendrickx JO, De Schepper R, Vangenechten L, Van Turnhout J, Verswyvel J, Becker KG, Zhang Y, Lehrmann E, Wood WH, ... ... Maudsley S, et al. Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. Mechanisms of Ageing and Development. 111150. PMID 31574270 DOI: 10.1016/J.Mad.2019.111150  0.763
2019 van Gastel J, Hendrickx JO, Leysen H, Martin B, Veenker L, Beuning S, Coppens V, Morrens M, Maudsley S. Enhanced Molecular Appreciation of Psychiatric Disorders Through High-Dimensionality Data Acquisition and Analytics. Methods in Molecular Biology (Clifton, N.J.). 2011: 671-723. PMID 31273728 DOI: 10.1007/978-1-4939-9554-7_39  0.756
2018 Hendrickx JO, van Gastel J, Leysen H, Santos-Otte P, Premont RT, Martin B, Maudsley S. GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders. Frontiers in Pharmacology. 9: 1484. PMID 30618771 DOI: 10.3389/Fphar.2018.01484  0.809
2018 van Gastel J, Hendrickx JO, Leysen H, Santos-Otte P, Luttrell LM, Martin B, Maudsley S. β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders. Frontiers in Pharmacology. 9: 1369. PMID 30546309 DOI: 10.3389/Fphar.2018.01369  0.811
2018 Anckaerts C, van Gastel J, Leysen V, Hinz R, Azmi A, Simoens P, Shah D, Kara F, Langbeen A, Bols P, Laloux C, Prevot V, Verhoye M, Maudsley S, Van der Linden A. Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality. Neurobiology of Aging. 74: 77-89. PMID 30439596 DOI: 10.1016/J.Neurobiolaging.2018.10.012  0.338
2018 Leysen H, van Gastel J, Hendrickx JO, Santos-Otte P, Martin B, Maudsley S. G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes. International Journal of Molecular Sciences. 19. PMID 30261591 DOI: 10.3390/Ijms19102919  0.811
2018 van Gastel J, Boddaert J, Jushaj A, Premont RT, Luttrell LM, Janssens J, Martin B, Maudsley S. GIT2-a keystone in ageing and age-related disease. Ageing Research Reviews. PMID 29452267 DOI: 10.1016/J.Arr.2018.02.002  0.825
2017 Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, et al. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing Research Reviews. 42: 40-55. PMID 29248758 DOI: 10.1016/J.Arr.2017.12.004  0.33
2017 Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S. Correction for Lu et al., "Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair". Molecular and Cellular Biology. 37. PMID 28801458 DOI: 10.1128/Mcb.00310-17  0.75
2017 Martin B, Wang R, Cong WN, Daimon CM, Wu WW, Ni B, Becker KG, Lehrmann E, Wood WH, Zhang Y, Etienne H, van Gastel J, Azmi A, Janssens J, Maudsley S. Altered learning, memory and social behavior in type 1 taste receptor subunit 3 knockout mice is associated with neuronal dysfunction. The Journal of Biological Chemistry. PMID 28522608 DOI: 10.1074/Jbc.M116.773820  0.804
2017 Luttrell LM, Maudsley S, Gesty-Palmer D. Translating in vitro ligand bias into in vivo efficacy. Cellular Signalling. PMID 28495495 DOI: 10.1016/J.Cellsig.2017.05.002  0.655
2017 Siddiqui S, Lustig A, Carter A, Sankar M, Daimon CM, Premont RT, Etienne H, van Gastel J, Azmi A, Janssens J, Becker KG, Zhang Y, Wood W, Lehrmann E, Martin JG, ... ... Maudsley S, et al. Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption. Aging. PMID 28260693 DOI: 10.18632/aging.101185  0.789
2017 Janssens J, Lu D, Ni B, Chadwick W, Siddiqui S, Azmi A, Etienne H, Jushaj A, van Gastel J, Martin B, Maudsley S. Development of Precision Small-Molecule Proneurotrophic Therapies for Neurodegenerative Diseases. Vitamins and Hormones. 104: 263-311. PMID 28215298 DOI: 10.1016/Bs.Vh.2016.10.006  0.816
2015 Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Frontiers in Endocrinology. 6: 191. PMID 26834700 DOI: 10.3389/Fendo.2015.00191  0.812
2015 Daimon CM, Jasien JM, Wood WH, Zhang Y, Becker KG, Silverman JL, Crawley JN, Martin B, Maudsley S. Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder. Frontiers in Physiology. 6: 324. PMID 26635614 DOI: 10.3389/Fphys.2015.00324  0.322
2015 Janssens J, Philtjens S, Kleinberger G, Van Mossevelde S, van der Zee J, Cacace R, Engelborghs S, Sieben A, Banzhaf-Strathmann J, Dillen L, Merlin C, Cuijt I, Robberecht C, Schmid B, Santens P, ... ... Maudsley S, et al. Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains. Acta Neuropathologica Communications. 3: 68. PMID 26555887 DOI: 10.1186/S40478-015-0246-7  0.761
2015 Luttrell LM, Maudsley S, Bohn LM. Fulfilling the Promise of 'Biased' GPCR Agonism. Molecular Pharmacology. PMID 26134495 DOI: 10.1124/Mol.115.099630  0.585
2015 Maudsley S, Martin B, Janssens J, Etienne H, Jushaj A, van Gastel J, Willemsen A, Chen H, Gesty-Palmer D, Luttrell LM. Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods (San Diego, Calif.). PMID 25986936 DOI: 10.1016/J.Ymeth.2015.05.013  0.809
2015 Maudsley S, Martin B, Gesty-Palmer D, Cheung H, Johnson C, Patel S, Becker KG, Wood WH, Zhang Y, Lehrmann E, Luttrell LM. Delineation of a conserved arrestin-biased signaling repertoire in vivo. Molecular Pharmacology. 87: 706-17. PMID 25637603 DOI: 10.1124/Mol.114.095224  0.798
2015 Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S. Nuclear GIT2 is an ATM substrate and promotes DNA repair. Molecular and Cellular Biology. 35: 1081-96. PMID 25605334 DOI: 10.1128/Mcb.01432-14  0.786
2015 Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH, Becker KG, Martin B, Maudsley S. Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model. The Journal of Biological Chemistry. 290: 2728-43. PMID 25505248 DOI: 10.1074/Jbc.M114.588608  0.729
2014 Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, et al. Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. The Journal of Experimental Medicine. 211: 2373-83. PMID 25366964 DOI: 10.1084/Jem.20140116  0.637
2014 Janssens J, Etienne H, Idriss S, Azmi A, Martin B, Maudsley S. Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor System. Frontiers in Endocrinology. 5: 142. PMID 25225492 DOI: 10.3389/Fendo.2014.00142  0.769
2014 Jasien JM, Daimon CM, Wang R, Shapiro BK, Martin B, Maudsley S. The effects of aging on the BTBR mouse model of autism spectrum disorder. Frontiers in Aging Neuroscience. 6: 225. PMID 25225482 DOI: 10.3389/Fnagi.2014.00225  0.367
2014 Wang R, van Keeken NM, Siddiqui S, Dijksman LM, Maudsley S, Derval D, van Dam PS, Martin B. Higher TNF-α, IGF-1, and Leptin Levels are Found in Tasters than Non-Tasters. Frontiers in Endocrinology. 5: 125. PMID 25120532 DOI: 10.3389/Fendo.2014.00125  0.638
2014 Wang R, Ross CA, Cai H, Cong WN, Daimon CM, Carlson OD, Egan JM, Siddiqui S, Maudsley S, Martin B. Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients. Frontiers in Physiology. 5: 231. PMID 25002850 DOI: 10.3389/Fphys.2014.00231  0.647
2014 Cai H, Maudsley S, Martin B. What is the role of metabolic hormones in taste buds of the tongue. Frontiers of Hormone Research. 42: 134-46. PMID 24732931 DOI: 10.1159/000358322  0.338
2014 Okun E, Griffioen KJ, Rothman S, Wan R, Cong WN, De Cabo R, Martin-Montalvo A, Levette A, Maudsley S, Martin B, Arumugam TV, Mattson MP. Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism. Brain, Behavior, and Immunity. 36: 90-100. PMID 24145051 DOI: 10.1016/J.Bbi.2013.10.013  0.315
2014 Cai H, Daimon CM, Cong WN, Wang R, Chirdon P, de Cabo R, Sévigny J, Maudsley S, Martin B. Longitudinal analysis of calorie restriction on rat taste bud morphology and expression of sweet taste modulators. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 532-44. PMID 24077597 DOI: 10.1093/Gerona/Glt129  0.318
2014 Mirsoian A, Bouchlaka MN, Sckisel G, Chen M, Pai CS, Maverakis E, Spencer R, Fishbein K, Siddiqui S, Monjazeb A, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, et al. Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice Blood. 124: 460-460. DOI: 10.1182/Blood.V124.21.460.460  0.648
2013 Mo J, Maudsley S, Martin B, Siddiqui S, Cheung H, Johnson CA. Classification of Alzheimer Diagnosis from ADNI Plasma Biomarker Data. 2013 Acm Conference On Bioinformatics, Computational Biology and Biomedical Informatics : Acm - Bcb 2013 : Washington, D.C., U.S.a., September 22 - 25, 2013 / Cathy Wu and Sridhar Hannenhalli, General Co-Chairs. Acm Conference On Bioinf.... 2013: 569. PMID 25599092 DOI: 10.1145/2506583.2506637  0.581
2013 Cai H, Cong WN, Daimon CM, Wang R, Tschöp MH, Sévigny J, Martin B, Maudsley S. Altered lipid and salt taste responsivity in ghrelin and GOAT null mice. Plos One. 8: e76553. PMID 24124572 DOI: 10.1371/Journal.Pone.0076553  0.309
2013 Cong WN, Wang R, Cai H, Daimon CM, Scheibye-Knudsen M, Bohr VA, Turkin R, Wood WH, Becker KG, Moaddel R, Maudsley S, Martin B. Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. Plos One. 8: e70257. PMID 23950916 DOI: 10.1371/Journal.Pone.0070257  0.336
2013 Martin B, Chen H, Daimon CM, Chadwick W, Siddiqui S, Maudsley S. Plurigon: three dimensional visualization and classification of high-dimensionality data. Frontiers in Physiology. 4: 190. PMID 23885241 DOI: 10.3389/Fphys.2013.00190  0.763
2013 Maudsley S, Siddiqui S, Martin B. Systems analysis of arrestin pathway functions. Progress in Molecular Biology and Translational Science. 118: 431-67. PMID 23764064 DOI: 10.1016/B978-0-12-394440-5.00017-6  0.698
2013 Chen H, Martin B, Daimon CM, Siddiqui S, Luttrell LM, Maudsley S. Textrous!: extracting semantic textual meaning from gene sets. Plos One. 8: e62665. PMID 23646135 DOI: 10.1371/Journal.Pone.0062665  0.729
2013 Siddiqui S, Cong WN, Daimon CM, Martin B, Maudsley S. BRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality. Frontiers in Endocrinology. 4: 46. PMID 23577003 DOI: 10.3389/Fendo.2013.00046  0.708
2013 Chen H, Martin B, Daimon CM, Maudsley S. Effective use of latent semantic indexing and computational linguistics in biological and biomedical applications. Frontiers in Physiology. 4: 8. PMID 23386833 DOI: 10.3389/Fphys.2013.00008  0.407
2013 Gesty-Palmer D, Yuan L, Martin B, Wood WH, Lee MH, Janech MG, Tsoi LC, Zheng WJ, Luttrell LM, Maudsley S. β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo. Molecular Endocrinology (Baltimore, Md.). 27: 296-314. PMID 23315939 DOI: 10.1210/Me.2012-1091  0.615
2013 Cai H, Chen H, Yi T, Daimon CM, Boyle JP, Peers C, Maudsley S, Martin B. VennPlex--a novel Venn diagram program for comparing and visualizing datasets with differentially regulated datapoints. Plos One. 8: e53388. PMID 23308210 DOI: 10.1371/Journal.Pone.0053388  0.434
2012 Chen H, Martin B, Cai H, Fiori JL, Egan JM, Siddiqui S, Maudsley S. Pancreas++: automated quantification of pancreatic islet cells in microscopy images. Frontiers in Physiology. 3: 482. PMID 23293605 DOI: 10.3389/Fphys.2012.00482  0.663
2012 Cong WN, Cai H, Wang R, Daimon CM, Maudsley S, Raber K, Canneva F, von Hörsten S, Martin B. Altered hypothalamic protein expression in a rat model of Huntington's disease. Plos One. 7: e47240. PMID 23094041 DOI: 10.1371/Journal.Pone.0047240  0.333
2012 Stranahan AM, Martin B, Chadwick W, Park SS, Wang L, Becker KG, Woodiii WH, Zhang Y, Maudsley S. Metabolic context regulates distinct hypothalamic transcriptional responses to antiaging interventions. International Journal of Endocrinology. 2012: 732975. PMID 22934110 DOI: 10.1155/2012/732975  0.759
2012 Martin B, Chadwick W, Cong WN, Pantaleo N, Daimon CM, Golden EJ, Becker KG, Wood WH, Carlson OD, Egan JM, Maudsley S. Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington disease is related to their physiological efficacy. The Journal of Biological Chemistry. 287: 31766-82. PMID 22822065 DOI: 10.1074/Jbc.M112.387316  0.778
2012 Maudsley S. G protein-coupled receptor biased agonism: development towards future selective therapeutics. Mini Reviews in Medicinal Chemistry. 12: 803. PMID 22757722 DOI: 10.2174/138955712800959161  0.372
2012 Siddiqui S, Fang M, Ni B, Lu D, Martin B, Maudsley S. Central role of the EGF receptor in neurometabolic aging. International Journal of Endocrinology. 2012: 739428. PMID 22754566 DOI: 10.1155/2012/739428  0.82
2012 Maudsley S, Patel SA, Park SS, Luttrell LM, Martin B. Functional signaling biases in G protein-coupled receptors: Game theory and receptor dynamics Mini-Reviews in Medicinal Chemistry. 12: 831-840. PMID 22681251 DOI: 10.2174/138955712800959071  0.657
2012 Chadwick W, Martin B, Chapter MC, Park SS, Wang L, Daimon CM, Brenneman R, Maudsley S. GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats. Plos One. 7: e36975. PMID 22606319 DOI: 10.1371/Journal.Pone.0036975  0.8
2012 Martin B, Chadwick W, Yi T, Park SS, Lu D, Ni B, Gadkaree S, Farhang K, Becker KG, Maudsley S. VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis. Plos One. 7: e36911. PMID 22606307 DOI: 10.1371/Journal.Pone.0036911  0.783
2012 Park SS, Wu WW, Zhou Y, Shen RF, Martin B, Maudsley S. Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC). Journal of Proteomics. 75: 3720-32. PMID 22575385 DOI: 10.1016/J.Jprot.2012.04.035  0.332
2012 Chadwick W, Mitchell N, Martin B, Maudsley S. Therapeutic targeting of the endoplasmic reticulum in Alzheimer's disease. Current Alzheimer Research. 9: 110-9. PMID 22329655 DOI: 10.2174/156720512799015055  0.728
2012 Cai H, Cong WN, Ji S, Rothman S, Maudsley S, Martin B. Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders. Current Alzheimer Research. 9: 5-17. PMID 22329649 DOI: 10.2174/156720512799015064  0.321
2012 Maudsley S, Chadwick W. Progressive and unconventional pharmacotherapeutic approaches to Alzheimer's disease therapy. Current Alzheimer Research. 9: 1-4. PMID 22329648 DOI: 10.2174/156720512799015082  0.688
2012 Shin YK, Cong WN, Cai H, Kim W, Maudsley S, Egan JM, Martin B. Age-related changes in mouse taste bud morphology, hormone expression, and taste responsivity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 336-44. PMID 22056740 DOI: 10.1093/Gerona/Glr192  0.361
2012 Martin B, Chadwick W, Yi T, Park S, Lu D, Ni B, Gadkaree S, Farhang K, Becker KG, Maudsley S. Correction: VENNTURE–A Novel Venn Diagram Investigational Tool for Multiple Pharmacological Dataset Analysis Plos One. 7. DOI: 10.1371/Annotation/27F1021C-B6F2-4B90-98Bc-Fcacd2679185  0.776
2011 Maudsley S, Chadwick W, Wang L, Zhou Y, Martin B, Park SS. Bioinformatic approaches to metabolic pathways analysis. Methods in Molecular Biology (Clifton, N.J.). 756: 99-130. PMID 21870222 DOI: 10.1007/978-1-61779-160-4_5  0.8
2011 Chadwick W, Mitchell N, Caroll J, Zhou Y, Park SS, Wang L, Becker KG, Zhang Y, Lehrmann E, Wood WH, Martin B, Maudsley S. Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity. Plos One. 6: e21660. PMID 21738757 DOI: 10.1371/Journal.Pone.0021660  0.774
2011 Chadwick W, Boyle JP, Zhou Y, Wang L, Park SS, Martin B, Wang R, Becker KG, Wood WH, Zhang Y, Peers C, Maudsley S. Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. Plos One. 6: e21638. PMID 21738745 DOI: 10.1371/Journal.Pone.0021638  0.768
2011 Park SS, Stranahan AM, Chadwick W, Zhou Y, Wang L, Martin B, Becker KG, Maudsley S. Cortical gene transcription response patterns to water maze training in aged mice. Bmc Neuroscience. 12: 63. PMID 21714909 DOI: 10.1186/1471-2202-12-63  0.783
2011 Kim W, Doyle ME, Liu Z, Lao Q, Shin YK, Carlson OD, Kim HS, Thomas S, Napora JK, Lee EK, Moaddel R, Wang Y, Maudsley S, Martin B, Kulkarni RN, et al. Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells. Diabetes. 60: 1198-209. PMID 21346174 DOI: 10.2337/Db10-1550  0.308
2011 Zhou Y, Yi T, Park SS, Chadwick W, Shen RF, Wu WW, Martin B, Maudsley S. Rapid and enhanced proteolytic digestion using electric-field-oriented enzyme reactor. Journal of Proteomics. 74: 1030-5. PMID 21338726 DOI: 10.1016/J.Jprot.2011.02.007  0.72
2011 Chadwick W, Keselman A, Park SS, Zhou Y, Wang L, Brenneman R, Martin B, Maudsley S. Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms. Journal of Signal Transduction. 2011: 636951. PMID 21258655 DOI: 10.1155/2011/636951  0.784
2011 Stranahan A, Chadwick W, Zhou Y, Park S, Wang L, Becker K, Wood W, Zhang Y, Martin B, Maudsley S. Wheel running and caloric restriction recruit distinct hypothalamic transcriptional profiles in wildtype and leptin receptor deficient mice Appetite. 57: S42. DOI: 10.1016/J.Appet.2011.05.275  0.787
2010 Chadwick W, Zhou Y, Park SS, Wang L, Mitchell N, Stone MD, Becker KG, Martin B, Maudsley S. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. Plos One. 5: e14352. PMID 21179406 DOI: 10.1371/Journal.Pone.0014352  0.788
2010 Chadwick W, Brenneman R, Martin B, Maudsley S. Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. International Journal of Alzheimer's Disease. 2010: 604792. PMID 21151659 DOI: 10.4061/2010/604792  0.796
2010 Shin YK, Martin B, Kim W, White CM, Ji S, Sun Y, Smith RG, Sévigny J, Tschöp MH, Maudsley S, Egan JM. Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants. Plos One. 5: e12729. PMID 20856820 DOI: 10.1371/Journal.Pone.0012729  0.327
2010 Maudsley S. New frontiers in G protein-coupled receptor regulation of neurological disorders. Cns & Neurological Disorders Drug Targets. 9: 525. PMID 20632974 DOI: 10.2174/187152710793361540  0.38
2010 Cong WN, Golden E, Pantaleo N, White CM, Maudsley S, Martin B. Ghrelin receptor signaling: a promising therapeutic target for metabolic syndrome and cognitive dysfunction. Cns & Neurological Disorders Drug Targets. 9: 557-63. PMID 20632971 DOI: 10.2174/187152710793361513  0.802
2010 Pantaleo N, Chadwick W, Park SS, Wang L, Zhou Y, Martin B, Maudsley S. The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disorders. Cns & Neurological Disorders Drug Targets. 9: 627-35. PMID 20632965 DOI: 10.2174/187152710793361504  0.802
2010 Wang L, Chadwick W, Park SS, Zhou Y, Silver N, Martin B, Maudsley S. Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration. Cns & Neurological Disorders Drug Targets. 9: 651-60. PMID 20632963 DOI: 10.2174/187152710793361559  0.81
2010 White CM, Ji S, Cai H, Maudsley S, Martin B. Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders. Cns & Neurological Disorders Drug Targets. 9: 661-6. PMID 20632962 DOI: 10.2174/187152710793361595  0.389
2010 Golden E, Emiliano A, Maudsley S, Windham BG, Carlson OD, Egan JM, Driscoll I, Ferrucci L, Martin B, Mattson MP. Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. Plos One. 5: e10099. PMID 20404913 DOI: 10.1371/Journal.Pone.0010099  0.301
2010 Martin B, Shin YK, White CM, Ji S, Kim W, Carlson OD, Napora JK, Chadwick W, Chapter M, Waschek JA, Mattson MP, Maudsley S, Egan JM. Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression. Diabetes. 59: 1143-52. PMID 20150284 DOI: 10.2337/Db09-0807  0.791
2010 Chapter MC, White CM, DeRidder A, Chadwick W, Martin B, Maudsley S. Chemical modification of Class II G protein-coupled receptor ligands: Frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies Pharmacology and Therapeutics. 125: 39-54. PMID 19686775 DOI: 10.1016/J.Pharmthera.2009.07.006  0.793
2010 Stranahan AM, Lee K, Becker KG, Zhang Y, Maudsley S, Martin B, Cutler RG, Mattson MP. Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice. Neurobiology of Aging. 31: 1937-49. PMID 19070401 DOI: 10.1016/J.Neurobiolaging.2008.10.016  0.317
2009 Stranahan AM, Zhou Y, Martin B, Maudsley S. Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents. Current Medicinal Chemistry. 16: 4668-78. PMID 19903142 DOI: 10.2174/092986709789878292  0.416
2009 Martin B, Dotson CD, Shin YK, Ji S, Drucker DJ, Maudsley S, Munger SD. Modulation of taste sensitivity by GLP-1 signaling in taste buds. Annals of the New York Academy of Sciences. 1170: 98-101. PMID 19686117 DOI: 10.1111/J.1749-6632.2009.03920.X  0.335
2009 Wang L, Martin B, Brenneman R, Luttrell LM, Maudsley S. Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders. The Journal of Pharmacology and Experimental Therapeutics. 331: 340-8. PMID 19667132 DOI: 10.1124/Jpet.109.156380  0.815
2009 Mattson MP, Maudsley S. Live longer sans the AT1A receptor. Cell Metabolism. 9: 403-5. PMID 19416709 DOI: 10.1016/J.Cmet.2009.04.002  0.31
2009 Martin B, Maudsley S, White CM, Egan JM. Hormones in the naso-oropharynx: endocrine modulation of taste and smell. Trends in Endocrinology and Metabolism: Tem. 20: 163-70. PMID 19359194 DOI: 10.1016/J.Tem.2009.01.006  0.324
2009 Martin B, Pearson M, Brenneman R, Golden E, Wood W, Prabhu V, Becker KG, Mattson MP, Maudsley S. Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment. Plos One. 4: e4146. PMID 19127293 DOI: 10.1371/Journal.Pone.0004146  0.659
2009 Martin B, Brenneman R, Golden E, Walent T, Becker KG, Prabhu VV, Wood W, Ladenheim B, Cadet JL, Maudsley S. Growth factor signals in neural cells: coherent patterns of interaction control multiple levels of molecular and phenotypic responses. The Journal of Biological Chemistry. 284: 2493-511. PMID 19038969 DOI: 10.1074/Jbc.M804545200  0.785
2009 Martin B, Golden E, Carlson OD, Pistell P, Zhou J, Kim W, Frank BP, Thomas S, Chadwick WA, Greig NH, Bates GP, Sathasivam K, Bernier M, Maudsley S, Mattson MP, et al. Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. Diabetes. 58: 318-28. PMID 18984744 DOI: 10.2337/Db08-0799  0.727
2008 Chadwick W, Magnus T, Martin B, Keselman A, Mattson MP, Maudsley S. Targeting TNF-alpha receptors for neurotherapeutics. Trends in Neurosciences. 31: 504-11. PMID 18774186 DOI: 10.1016/J.Tins.2008.07.005  0.708
2008 Martin B, Brenneman R, Becker KG, Gucek M, Cole RN, Maudsley S. iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease. Plos One. 3: e2750. PMID 18648646 DOI: 10.1371/Journal.Pone.0002750  0.672
2008 Martin B, Pearson M, Brenneman R, Golden E, Keselman A, Iyun T, Carlson OD, Egan JM, Becker KG, Wood W, Prabhu V, de Cabo R, Maudsley S, Mattson MP. Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males. Plos One. 3: e2398. PMID 18545695 DOI: 10.1371/Journal.Pone.0002398  0.778
2008 Martin B, Golden E, Carlson OD, Egan JM, Mattson MP, Maudsley S. Caloric restriction: impact upon pituitary function and reproduction. Ageing Research Reviews. 7: 209-24. PMID 18329344 DOI: 10.1016/J.Arr.2008.01.002  0.32
2008 Martin B, Golden E, Keselman A, Stone M, Mattson MP, Egan JM, Maudsley S. Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body. Histology and Histopathology. 23: 237-50. PMID 17999380 DOI: 10.14670/Hh-23.237  0.79
2007 López de Maturana R, Martin B, Millar RP, Brown P, Davidson L, Pawson AJ, Nicol MR, Mason JI, Barran P, Naor Z, Maudsley S. GnRH-mediated DAN production regulates the transcription of the GnRH receptor in gonadotrope cells. Neuromolecular Medicine. 9: 230-48. PMID 17914181 DOI: 10.1007/S12017-007-8004-Z  0.707
2007 Martin B, Pearson M, Kebejian L, Golden E, Keselman A, Bender M, Carlson O, Egan J, Ladenheim B, Cadet JL, Becker KG, Wood W, Duffy K, Vinayakumar P, Maudsley S, et al. Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess. Endocrinology. 148: 4318-33. PMID 17569758 DOI: 10.1210/En.2007-0161  0.774
2007 Maudsley S, Naor Z, Bonfil D, Davidson L, Karali D, Pawson AJ, Larder R, Pope C, Nelson N, Millar RP, Brown P. Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene. Molecular Endocrinology (Baltimore, Md.). 21: 1216-33. PMID 17327421 DOI: 10.1210/Me.2006-0053  0.699
2007 Maudsley S, Martin B, Luttrell LM. G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics. Current Alzheimer Research. 4: 3-19. PMID 17316162 DOI: 10.2174/156720507779939850  0.642
2006 Maudsley S, Davidson L, Pawson AJ, Freestone SH, López de Maturana R, Thomson AA, Millar RP. Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5. Neuroendocrinology. 84: 285-300. PMID 17202804 DOI: 10.1159/000098402  0.692
2005 Martin B, Lopez de Maturana R, Brenneman R, Walent T, Mattson MP, Maudsley S. Class II G protein-coupled receptors and their ligands in neuronal function and protection. Neuromolecular Medicine. 7: 3-36. PMID 16052036 DOI: 10.1385/Nmm:7:1-2:003  0.794
2005 Maudsley S, Martin B, Luttrell LM. The origins of diversity and specificity in g protein-coupled receptor signaling. The Journal of Pharmacology and Experimental Therapeutics. 314: 485-94. PMID 15805429 DOI: 10.1124/jpet.105.083121  0.629
2005 Pawson AJ, Maudsley S, Morgan K, Davidson L, Naor Z, Millar RP. Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment. Endocrinology. 146: 2639-49. PMID 15761034 DOI: 10.1210/En.2005-0133  0.691
2004 Maudsley S, Davidson L, Pawson AJ, Chan R, López de Maturana R, Millar RP. Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Galphai-coupling state of the type I GnRH receptor. Cancer Research. 64: 7533-44. PMID 15492280 DOI: 10.1158/0008-5472.CAN-04-1360  0.743
2004 Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Gonadotropin-releasing hormone receptors. Endocrine Reviews. 25: 235-75. PMID 15082521 DOI: 10.1210/er.2003-0002  0.339
2004 Davidson L, Pawson AJ, López de Maturana R, Freestone SH, Barran P, Millar RP, Maudsley S. Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-zeta and its association with active c-src. The Journal of Biological Chemistry. 279: 11906-16. PMID 14707140 DOI: 10.1074/Jbc.M310784200  0.717
2004 Davidson L, Pawson AJ, Millar RP, Maudsley S. Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor. The Journal of Biological Chemistry. 279: 1980-93. PMID 14559894 DOI: 10.1074/Jbc.M309827200  0.723
2000 Maudsley S, Zamah AM, Rahman N, Blitzer JT, Luttrell LM, Lefkowitz RJ, Hall RA. Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity. Molecular and Cellular Biology. 20: 8352-63. PMID 11046132 DOI: 10.1128/Mcb.20.22.8352-8363.2000  0.808
2000 Roudabush FL, Pierce KL, Maudsley S, Khan KD, Luttrell LM. Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. The Journal of Biological Chemistry. 275: 22583-9. PMID 10807918 DOI: 10.1074/Jbc.M002915200  0.799
2000 Miller WE, Maudsley S, Ahn S, Khan KD, Luttrell LM, Lefkowitz RJ. beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis. The Journal of Biological Chemistry. 275: 11312-9. PMID 10753943 DOI: 10.1074/Jbc.275.15.11312  0.793
2000 Maudsley S, Pierce KL, Zamah AM, Miller WE, Ahn S, Daaka Y, Lefkowitz RJ, Luttrell LM. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. The Journal of Biological Chemistry. 275: 9572-80. PMID 10734107 DOI: 10.1074/Jbc.275.13.9572  0.806
2000 Pierce KL, Maudsley S, Daaka Y, Luttrell LM, Lefkowitz RJ. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 1489-94. PMID 10677489 DOI: 10.1073/PNAS.97.4.1489  0.754
2000 Seo B, Choy EW, Maudsley S, Miller WE, Wilson BA, Luttrell LM. Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor. The Journal of Biological Chemistry. 275: 2239-45. PMID 10636931 DOI: 10.1074/Jbc.275.3.2239  0.713
1999 Della Rocca GJ, Maudsley S, Daaka Y, Lefkowitz RJ, Luttrell LM. Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. The Journal of Biological Chemistry. 274: 13978-84. PMID 10318809 DOI: 10.1074/Jbc.274.20.13978  0.771
1999 Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, Lin F, Kawakatsu H, Owada K, Luttrell DK, Caron MG, Lefkowitz RJ. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science (New York, N.Y.). 283: 655-61. PMID 9924018 DOI: 10.1126/Science.283.5402.655  0.814
1999 Ahn S, Maudsley S, Luttrell LM, Lefkowitz RJ, Daaka Y. Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. The Journal of Biological Chemistry. 274: 1185-8. PMID 9880482 DOI: 10.1074/Jbc.274.3.1185  0.802
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