| Year |
Citation |
Score |
| 2023 |
Dubois-Chevalier J, Gheeraert C, Berthier A, Boulet C, Dubois V, Guille L, Fourcot M, Marot G, Gauthier K, Dubuquoy L, Staels B, Lefebvre P, Eeckhoute J. An extended transcription factor regulatory network controls hepatocyte identity. Embo Reports. e57020. PMID 37424431 DOI: 10.15252/embr.202357020 |
0.361 |
|
| 2022 |
Bobowski-Gerard M, Boulet C, Zummo FP, Dubois-Chevalier J, Gheeraert C, Bou Saleh M, Strub JM, Farce A, Ploton M, Guille L, Vandel J, Bongiovanni A, Very N, Woitrain E, Deprince A, ... ... Eeckhoute J, et al. Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis. Nature Communications. 13: 5324. PMID 36088459 DOI: 10.1038/s41467-022-33063-9 |
0.343 |
|
| 2022 |
Salbert G, Sérandour AA, Staels B, Lefebvre P, Eeckhoute J. The conundrum of the functional relationship between transcription factors and chromatin. Epigenomics. PMID 35034474 DOI: 10.2217/epi-2021-0509 |
0.306 |
|
| 2020 |
Dubois V, Staels B, Lefebvre P, Verzi MP, Eeckhoute J. Control of Cell Identity by the Nuclear Receptor HNF4 in Organ Pathophysiology. Cells. 9. PMID 32998360 DOI: 10.3390/cells9102185 |
0.306 |
|
| 2020 |
Dubois V, Gheeraert C, Vankrunkelsven W, Dubois-Chevalier J, Dehondt H, Bobowski-Gerard M, Vinod M, Zummo FP, Güiza F, Ploton M, Dorchies E, Pineau L, Boulinguiez A, Vallez E, Woitrain E, ... ... Eeckhoute J, et al. Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver. Molecular Systems Biology. 16: e9156. PMID 32407006 DOI: 10.15252/Msb.20199156 |
0.335 |
|
| 2020 |
Dubois-Chevalier J, Dubois V, Staels B, Lefebvre P, Eeckhoute J. Perspectives on the use of super-enhancers as a defining feature of cell/tissue-identity genes. Epigenomics. PMID 32396464 DOI: 10.2217/Epi-2019-0290 |
0.395 |
|
| 2019 |
Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, et al. Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Reports. 29: 1410-1418.e6. PMID 31693883 DOI: 10.1016/J.Celrep.2019.09.073 |
0.308 |
|
| 2019 |
Butruille L, Marousez L, Pourpe C, Oger F, Lecoutre S, Catheline D, Görs S, Metges CC, Guinez C, Laborie C, Deruelle P, Eeckhoute J, Breton C, Legrand P, Lesage J, et al. Maternal high-fat diet during suckling programs visceral adiposity and epigenetic regulation of adipose tissue stearoyl-CoA desaturase-1 in offspring. International Journal of Obesity (2005). PMID 30622312 DOI: 10.1038/S41366-018-0310-Z |
0.31 |
|
| 2019 |
Vankrunkelsven W, Dubois V, Derese I, Langouche L, Eeckhoute J, Van Den Berghe G, Vanhorebeek I. SAT-155 Temporal Activation of the Unfolded Protein Response and Concomitant Downregulation of Key Hepatic Transcription Factors in Critical Illness Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-155 |
0.364 |
|
| 2018 |
Berthier A, Vinod M, Porez G, Steenackers A, Alexandre J, Yamakawa N, Gheeraert C, Ploton M, Maréchal X, Dubois-Chevalier J, Hovasse A, Schaeffer-Reiss C, Cianférani S, Rolando C, Bray F, ... ... Eeckhoute J, et al. Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397120 DOI: 10.1073/Pnas.1805397115 |
0.439 |
|
| 2018 |
Bobowski-Gerard M, Zummo FP, Staels B, Lefebvre P, Eeckhoute J. Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response. Cells. 7. PMID 30217095 DOI: 10.3390/Cells7090137 |
0.338 |
|
| 2018 |
Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi-Blum K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P. The Nuclear Bile Acid Receptor FXR is a PKA- and FOXA2-Sensitive Activator of Fasting Hepatic Gluconeogenesis. Journal of Hepatology. PMID 29981427 DOI: 10.1016/J.Jhep.2018.06.022 |
0.352 |
|
| 2017 |
Pourcet B, Zecchin M, Ferri L, Beauchamp J, Sitaula S, Billon C, Delhaye S, Vanhoutte J, Mayeuf-Louchart A, Thorel Q, Haas J, Eeckhoute J, Dombrowicz D, Duhem C, Boulinguiez A, et al. Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity Of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice. Gastroenterology. PMID 29277561 DOI: 10.1053/J.Gastro.2017.12.019 |
0.332 |
|
| 2017 |
Dubois-Chevalier J, Mazrooei P, Lupien M, Staels B, Lefebvre P, Eeckhoute J. Organizing combinatorial transcription factor recruitment at cis-regulatory modules. Transcription. 1-15. PMID 29105538 DOI: 10.1080/21541264.2017.1394424 |
0.602 |
|
| 2017 |
Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, ... ... Eeckhoute J, et al. The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ. Scientific Reports. 7: 14087. PMID 29075020 DOI: 10.1038/S41598-017-14570-Y |
0.426 |
|
| 2017 |
Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, ... ... Eeckhoute J, et al. Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin. Jci Insight. 2. PMID 28679947 DOI: 10.1172/Jci.Insight.92264 |
0.347 |
|
| 2017 |
Chinetti-Gbaguidi G, Daoudi M, Rosa M, Vinod M, Louvet L, Copin C, Fanchon M, Vanhoutte J, Derudas B, Belloy L, Haulon S, Zawadzki C, Susen S, Massy ZA, Eeckhoute J, et al. Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity. Circulation Research. PMID 28438779 DOI: 10.1161/Circresaha.116.310262 |
0.318 |
|
| 2017 |
Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Penderia G, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, ... ... Eeckhoute J, et al. The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions. Genome Research. PMID 28400425 DOI: 10.1101/Gr.217075.116 |
0.65 |
|
| 2017 |
Le-Guevel R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G. Inactivation of the nuclear orphan receptor COUP-TFII by small chemicals. Acs Chemical Biology. PMID 28059499 DOI: 10.1021/Acschembio.6B00593 |
0.4 |
|
| 2015 |
Dubois-Chevalier J, Staels B, Lefebvre P, Eeckhoute J. The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation. Nucleus (Austin, Tex.). 6: 15-8. PMID 25565413 DOI: 10.1080/19491034.2015.1004258 |
0.499 |
|
| 2014 |
Dubois-Chevalier J, Oger F, Dehondt H, Firmin FF, Gheeraert C, Staels B, Lefebvre P, Eeckhoute J. A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation. Nucleic Acids Research. 42: 10943-59. PMID 25183525 DOI: 10.1093/Nar/Gku780 |
0.498 |
|
| 2014 |
Quintin J, Péron CL, Palierne G, Bizot M, Cunha S, Sérandour AA, Avner S, Henry C, Percevault F, Belaud-Rotureau MA, Huet S, Watrin E, Eeckhoute J, Legagneux V, Salbert G, et al. Dynamic estrogen receptor interactomes control estrogen-responsive trefoil factor (TFF) locus cell-specific activities Molecular and Cellular Biology. 34: 2418-2436. PMID 24752895 DOI: 10.1128/Mcb.00918-13 |
0.495 |
|
| 2014 |
Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P, Salbert G, Staels B, Lefebvre P, Eeckhoute J. Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes. The Journal of Biological Chemistry. 289: 708-22. PMID 24288131 DOI: 10.1074/Jbc.M113.526996 |
0.443 |
|
| 2014 |
Berrabah W, Aumercier P, Gheeraert C, Dehondt H, Bouchaert E, Alexandre J, Ploton M, Mazuy C, Caron S, Tailleux A, Eeckhoute J, Lefebvre T, Staels B, Lefebvre P. Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR). Hepatology (Baltimore, Md.). 59: 2022-33. PMID 24037988 DOI: 10.1002/Hep.26710 |
0.33 |
|
| 2013 |
Mazuy C, Ploton M, Eeckhoute J, Berrabah W, Staels B, Lefebvre P, Helleboid-Chapman A. Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic β-cells. Febs Letters. PMID 24512852 DOI: 10.1016/J.Febslet.2013.10.024 |
0.398 |
|
| 2013 |
Mazuy C, Ploton M, Eeckhoute J, Berrabah W, Staels B, Lefebvre P, Helleboid-Chapman A. Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic β-cells. Febs Letters. 587: 3883-90. PMID 24396871 |
0.323 |
|
| 2013 |
Rommelaere S, Millet V, Gensollen T, Bourges C, Eeckhoute J, Hennuyer N, Baugé E, Chasson L, Cacciatore I, Staels B, Pitari G, Galland F, Naquet P. PPARalpha regulates the production of serum Vanin-1 by liver. Febs Letters. 587: 3742-8. PMID 24140347 DOI: 10.1016/J.Febslet.2013.09.046 |
0.353 |
|
| 2012 |
Cowper-Sal lari R, Zhang X, Wright JB, Bailey SD, Cole MD, Eeckhoute J, Moore JH, Lupien M. Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nature Genetics. 44: 1191-8. PMID 23001124 DOI: 10.1038/Ng.2416 |
0.577 |
|
| 2012 |
Eeckhoute J, Oger F, Staels B, Lefebvre P. Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity. Ppar Research. 2012: 164140. PMID 22991504 DOI: 10.1155/2012/164140 |
0.454 |
|
| 2012 |
Sérandour AA, Avner S, Oger F, Bizot M, Percevault F, Lucchetti-Miganeh C, Palierne G, Gheeraert C, Barloy-Hubler F, Péron CL, Madigou T, Durand E, Froguel P, Staels B, Lefebvre P, ... ... Eeckhoute J, et al. Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers. Nucleic Acids Research. 40: 8255-65. PMID 22730288 DOI: 10.1093/Nar/Gks595 |
0.464 |
|
| 2012 |
Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F, Vandewalle B, Moerman E, Gmyr V, Kerr-Conte J, Eeckhoute J, Staels B, Lefebvre P. The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells. Molecular Endocrinology (Baltimore, Md.). 26: 399-413. PMID 22301783 DOI: 10.1210/Me.2011-1317 |
0.42 |
|
| 2012 |
Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B, Noel B, Eeckhoute J, Lefebvre P, Seckl JR, Staels B. Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 677-85. PMID 22207732 DOI: 10.1161/Atvbaha.111.241364 |
0.319 |
|
| 2011 |
Zhang C, Wang L, Wu D, Chen H, Chen Z, Thomas-Ahner JM, Zynger DL, Eeckhoute J, Yu J, Luo J, Brown M, Clinton SK, Nephew KP, Huang TH, Li W, et al. Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer. Cancer Research. 71: 6738-48. PMID 21900400 DOI: 10.1158/0008-5472.Can-11-1882 |
0.364 |
|
| 2011 |
Magnani L, Eeckhoute J, Lupien M. Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends in Genetics : Tig. 27: 465-74. PMID 21885149 DOI: 10.1016/J.Tig.2011.07.002 |
0.638 |
|
| 2011 |
Boudot A, Kerdivel G, Habauzit D, Eeckhoute J, Le Dily F, Flouriot G, Samson M, Pakdel F. Differential estrogen-regulation of CXCL12 chemokine receptors, CXCR4 and CXCR7, contributes to the growth effect of estrogens in breast cancer cells. Plos One. 6: e20898. PMID 21695171 DOI: 10.1371/Journal.Pone.0020898 |
0.428 |
|
| 2011 |
Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G, Eeckhoute J. Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers. Genome Research. 21: 555-65. PMID 21233399 DOI: 10.1101/Gr.111534.110 |
0.66 |
|
| 2010 |
Lupien M, Meyer CA, Bailey ST, Eeckhoute J, Cook J, Westerling T, Zhang X, Carroll JS, Rhodes DR, Liu XS, Brown M. Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance. Genes & Development. 24: 2219-27. PMID 20889718 DOI: 10.1101/Gad.1944810 |
0.598 |
|
| 2009 |
Eeckhoute J, Métivier R, Salbert G. Defining specificity of transcription factor regulatory activities. Journal of Cell Science. 122: 4027-34. PMID 19910494 DOI: 10.1242/Jcs.054916 |
0.532 |
|
| 2009 |
Eeckhoute J, Lupien M, Brown M. Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies. Methods in Molecular Biology (Clifton, N.J.). 556: 155-64. PMID 19488877 DOI: 10.1007/978-1-60327-192-9_11 |
0.591 |
|
| 2009 |
Nucera C, Eeckhoute J, Finn S, Carroll JS, Ligon AH, Priolo C, Fadda G, Toner M, Sheils O, Attard M, Pontecorvi A, Nose V, Loda M, Brown M. FOXA1 is a potential oncogene in anaplastic thyroid carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3680-9. PMID 19470727 DOI: 10.1158/1078-0432.Ccr-08-3155 |
0.303 |
|
| 2009 |
Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, Brown M. Coactivator function defines the active estrogen receptor alpha cistrome. Molecular and Cellular Biology. 29: 3413-23. PMID 19364822 DOI: 10.1128/Mcb.00020-09 |
0.63 |
|
| 2009 |
Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M. Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Research. 19: 372-80. PMID 19129543 DOI: 10.1101/Gr.084582.108 |
0.646 |
|
| 2008 |
Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, Brown M. Unique ERalpha cistromes control cell type-specific gene regulation. Molecular Endocrinology (Baltimore, Md.). 22: 2393-406. PMID 18818283 DOI: 10.1210/Me.2008-0100 |
0.641 |
|
| 2008 |
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell. 132: 958-70. PMID 18358809 DOI: 10.1016/J.Cell.2008.01.018 |
0.653 |
|
| 2008 |
Leleu X, Eeckhoute J, Jia X, Roccaro AM, Moreau AS, Farag M, Sacco A, Ngo HT, Runnels J, Melhem MR, Burwick N, Azab A, Azab F, Hunter Z, Hatjiharissi E, et al. Targeting NF-kappaB in Waldenstrom macroglobulinemia. Blood. 111: 5068-77. PMID 18334673 DOI: 10.1182/Blood-2007-09-115170 |
0.311 |
|
| 2007 |
Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Research. 67: 6477-83. PMID 17616709 DOI: 10.1158/0008-5472.Can-07-0746 |
0.598 |
|
| 2006 |
Eeckhoute J, Briche I, Kurowska M, Formstecher P, Laine B. Hepatocyte nuclear factor 4 alpha ligand binding and F domains mediate interaction and transcriptional synergy with the pancreatic islet LIM HD transcription factor Isl1. Journal of Molecular Biology. 364: 567-81. PMID 17022998 DOI: 10.1016/J.Jmb.2006.07.096 |
0.451 |
|
| 2006 |
Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/Ng1901 |
0.466 |
|
| 2006 |
Eeckhoute J, Carroll JS, Geistlinger TR, Torres-Arzayus MI, Brown M. A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes & Development. 20: 2513-26. PMID 16980581 DOI: 10.1101/Gad.1446006 |
0.495 |
|
| 2005 |
Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/J.Cell.2005.05.008 |
0.47 |
|
| 2004 |
Eeckhoute J, Formstecher P, Laine B. Hepatocyte nuclear factor 4alpha enhances the hepatocyte nuclear factor 1alpha-mediated activation of transcription. Nucleic Acids Research. 32: 2586-93. PMID 15141028 DOI: 10.1093/Nar/Gkh581 |
0.476 |
|
| 2003 |
Eeckhoute J, Oxombre B, Formstecher P, Lefebvre P, Laine B. Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity. Nucleic Acids Research. 31: 6640-50. PMID 14602925 DOI: 10.1093/Nar/Gkg850 |
0.367 |
|
| 2003 |
Eeckhoute J, Moerman E, Bouckenooghe T, Lukoviak B, Pattou F, Formstecher P, Kerr-Conte J, Vandewalle B, Laine B. Hepatocyte nuclear factor 4 alpha isoforms originated from the P1 promoter are expressed in human pancreatic beta-cells and exhibit stronger transcriptional potentials than P2 promoter-driven isoforms. Endocrinology. 144: 1686-94. PMID 12697672 DOI: 10.1210/En.2002-0024 |
0.386 |
|
| 2002 |
Oxombre B, Moerman E, Eeckhoute J, Formstecher P, Laine B. Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells. Journal of Molecular Medicine (Berlin, Germany). 80: 423-30. PMID 12110948 DOI: 10.1007/S00109-002-0340-8 |
0.313 |
|
| 2001 |
Eeckhoute J, Formstecher P, Laine B. Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator. Molecular Endocrinology (Baltimore, Md.). 15: 1200-10. PMID 11435618 DOI: 10.1210/Mend.15.7.0670 |
0.44 |
|
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