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Luqing Shang - Publications

Affiliations: 
2018 Georgia State University, Atlanta, GA, United States 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wang H, Pei R, Li X, Deng W, Xing S, Zhang Y, Zhang C, He S, Sun H, Xiao S, Xiong J, Zhang Y, Chen X, Wang Y, Guo Y, ... ... Shang L, et al. The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. European Journal of Medicinal Chemistry. 238: 114458. PMID 35635946 DOI: 10.1016/j.ejmech.2022.114458  0.341
2022 Wang Y, Xu B, Ma S, Wang H, Shang L, Zhu C, Ye S. Discovery of SARS-CoV-2 3CL Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions. International Journal of Molecular Sciences. 23. PMID 35216507 DOI: 10.3390/ijms23042392  0.324
2021 Liu M, Xu B, Ma Y, Shang L, Ye S, Wang Y. Reversible covalent inhibitors suppress enterovirus 71 infection by targeting the 3C protease. Antiviral Research. 105102. PMID 34082057 DOI: 10.1016/j.antiviral.2021.105102  0.347
2020 Liang X, Zhang L, Shi B, Chang H, Qiao D, Shen T, Zhao W, Yin Z, Shang L. Design and application of near-infrared fluorophore based on a novel thiazolidinedione-functionalized dicyanoisophorone. Talanta. 220: 121433. PMID 32928437 DOI: 10.1016/J.Talanta.2020.121433  0.316
2020 Qiao D, Li L, Shen T, Yang J, Chang H, Liang X, Zhang L, Wang Q, Liu N, Zhao W, Shang L. Establishment of a Customizable Fluorescent Probe Platform for the Organelle-targeted Bioactive Species Detection. Acs Sensors. PMID 32627537 DOI: 10.1021/Acssensors.0C00992  0.32
2020 Wang H, He S, Deng W, Zhang Y, Li G, Sun J, Zhao W, Guo Y, Yin Z, Li D, Shang L. Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis. 10: 5871-5890. PMID 32391184 DOI: 10.1021/Acscatal.0C00110  0.347
2020 Zhao X, Fan Z, Qiao Y, Chen Y, Wang S, Yue X, Shen T, Liu W, Yang J, Gao H, Zhan X, Shang L, Yin Y, Zhao W, Ding D, et al. AIEgens Conjugation Improves Photothermal Efficacy and NIR Imaging of Heptamethine Cyanine IR-780. Acs Applied Materials & Interfaces. PMID 32167287 DOI: 10.1021/Acsami.0C01715  0.316
2020 Li G, Liu X, Yang M, Zhang G, Wang Z, Guo K, Gao Y, Jiao P, Sun J, Chen C, Wang H, Deng W, Xiao H, Li S, Wu H, ... ... Shang L, et al. Crystal structure of the African swine fever virus pS273R protease and implications for inhibitor design. Journal of Virology. PMID 32075933 DOI: 10.1128/Jvi.02125-19  0.354
2019 Ma Y, Li L, He S, Shang C, Sun Y, Liu N, Meek TD, Wang Y, Shang L. Application of Dually Activated Michael Acceptor to the Rational Design of Reversible Covalent Inhibitor for Enterovirus 71 3C Protease. Journal of Medicinal Chemistry. PMID 31184893 DOI: 10.1021/Acs.Jmedchem.9B00387  0.441
2018 Qiao D, Shen T, Zhu M, Liang X, Zhang L, Yin Z, Wang B, Shang L. A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting HS and various thiol species in solution and in live cells. Chemical Communications (Cambridge, England). PMID 30411108 DOI: 10.1039/C8Cc07761D  0.445
2018 Ma Y, Shang C, Yang P, Li L, Zhai Y, Yin Z, Wang B, Shang L. 4-Iminooxazolidin-2-one as a bioisostere of the cyanohydrin moiety: inhibitors of enterovirus 71 3C protease. Journal of Medicinal Chemistry. PMID 30365311 DOI: 10.1021/Acs.Jmedchem.8B01335  0.547
2018 Nie Q, Xu X, Zhang Q, Ma Y, Yin Z, Shang L. 3D-quantitative structure-activity relationship study for the design of novel enterovirus A71 3C protease inhibitors. Chemical Biology & Drug Design. PMID 29877617 DOI: 10.1111/Cbdd.13344  0.432
2018 Fu S, Nie Q, Ma Y, Song P, Ren X, Luo C, Shang L, Yin Z. Target-guided screening of fragments (TGSOF) in the discovery of inhibitors against EV-A71 3C protease. Chemical Communications (Cambridge, England). PMID 29497732 DOI: 10.1039/C8Cc00469B  0.38
2017 Wang Y, Cao L, Zhai Y, Yin Z, Sun Y, Shang L. Structure of EV71 3C(pro) in complex with NK-1.8k: Indications for the development of anti-enterovirus protease inhibitor. Antimicrobial Agents and Chemotherapy. PMID 28461310 DOI: 10.1128/Aac.00298-17  0.368
2017 Wang Y, Cao L, Zhai Y, Ma J, Nie Q, Li T, Yin Z, Sun Y, Shang L. Inhibition of enterovirus 71 replication by an α-hydroxy-nitrile derivative NK-1.9k. Antiviral Research. PMID 28063993 DOI: 10.1016/J.Antiviral.2017.01.002  0.372
2016 Zeng D, Zhang R, Nie Q, Cao L, Shang L, Yin Z. Discovery of 2'-α-C-Methyl-2'-β-C-fluorouridine Phosphoramidate Prodrugs as Inhibitors of Hepatitis C Virus. Acs Medicinal Chemistry Letters. 7: 1197-1201. PMID 27994763 DOI: 10.1021/Acsmedchemlett.6B00270  0.365
2016 Zhai Y, Ma Y, Ma F, Nie Q, Ren X, Wang Y, Shang L, Yin Z. Structure-activity relationship study of peptidomimetic aldehydes as enterovirus 71 3C protease inhibitors. European Journal of Medicinal Chemistry. 124: 559-573. PMID 27614190 DOI: 10.1016/J.Ejmech.2016.08.064  0.395
2016 Han Z, Liang X, Wang Y, Qing J, Cao L, Shang L, Yin Z. The discovery of indole derivatives as novel hepatitis C virus inhibitors. European Journal of Medicinal Chemistry. 116: 147-155. PMID 27061978 DOI: 10.1016/J.Ejmech.2016.03.062  0.369
2016 Zeng D, Ma Y, Zhang R, Nie Q, Cui Z, Wang Y, Shang L, Yin Z. Synthesis and structure-activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26916437 DOI: 10.1016/J.Bmcl.2016.02.039  0.436
2015 Guo Y, Wang Y, Cao L, Wang P, Qing J, Zheng Q, Shang L, Yin Z, Sun Y. A conserved inhibitory mechanism of a lycorine derivative against enterovirus and hepatitis C virus. Antimicrobial Agents and Chemotherapy. PMID 26596952 DOI: 10.1128/Aac.02274-15  0.324
2015 Zhai Y, Zhao X, Cui Z, Wang M, Wang Y, Li L, Sun Q, Yang X, Zeng D, Liu Y, Sun Y, Lou Z, Shang L, Yin Z. Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease. Journal of Medicinal Chemistry. PMID 26571192 DOI: 10.1021/Acs.Jmedchem.5B01013  0.412
2015 Shang L, Zhang S, Yang X, Sun J, Li L, Cui Z, He Q, Guo Y, Sun Y, Yin Z. Biochemical characterization of recombinant Enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay. Antimicrobial Agents and Chemotherapy. 59: 1827-36. PMID 25421478 DOI: 10.1128/Aac.04698-14  0.431
2014 Li L, Basavannacharya C, Chan KW, Shang L, Vasudevan SG, Yin Z. Structure-guided Discovery of a Novel Non-peptide Inhibitor of Dengue Virus NS2B-NS3 Protease. Chemical Biology & Drug Design. PMID 25533891 DOI: 10.1111/Cbdd.12500  0.385
2014 Shang L, Wang Y, Qing J, Shu B, Cao L, Lou Z, Gong P, Sun Y, Yin Z. An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation. Antiviral Research. 112: 47-58. PMID 25446894 DOI: 10.1016/J.Antiviral.2014.10.009  0.37
2014 Ding MZ, Yan HF, Li LF, Zhai F, Shang LQ, Yin Z, Yuan YJ. Biosynthesis of Taxadiene in Saccharomyces cerevisiae : selection of geranylgeranyl diphosphate synthase directed by a computer-aided docking strategy. Plos One. 9: e109348. PMID 25295588 DOI: 10.1371/Journal.Pone.0109348  0.305
2014 Wang P, Li LF, Wang QY, Shang LQ, Shi PY, Yin Z. Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives. Chemmedchem. 9: 1522-33. PMID 24574246 DOI: 10.1002/cmdc.201300505  0.349
2014 Wang P, Yuan HH, Zhang X, Li YP, Shang LQ, Yin Z. Novel lycorine derivatives as anticancer agents: synthesis and in vitro biological evaluation. Molecules (Basel, Switzerland). 19: 2469-80. PMID 24566315 DOI: 10.3390/Molecules19022469  0.384
2014 Shang L, Lin K, Yin Z. Resistance mutations against HCV protease inhibitors and antiviral drug design. Current Pharmaceutical Design. 20: 694-703. PMID 23688081 DOI: 10.2174/13816128113199990008  0.339
2012 Xu Y, Zhang L, Li M, Xu W, Fang H, Shang L. QSAR studies of aminopeptidase N/CD13 (APN) inhibitors with the scaffold 3-phenylpropane-1,2-diamine and molecular docking Medicinal Chemistry Research. 21: 1000-1015. DOI: 10.1007/S00044-011-9597-1  0.375
2011 Schüller A, Yin Z, Brian Chia CS, Doan DN, Kim HK, Shang L, Loh TP, Hill J, Vasudevan SG. Tripeptide inhibitors of dengue and West Nile virus NS2B-NS3 protease. Antiviral Research. 92: 96-101. PMID 21763725 DOI: 10.1016/J.Antiviral.2011.07.002  0.416
2010 Wang Q, Xu F, Mou J, Zhang J, Shang L, Luan Y, Yuan Y, Liu Y, Li M, Fang H, Wang B, Xu W. Design, synthesis and preliminary activity evaluation of novel L-lysine derivatives as aminopeptidase N/CD13 inhibitors. Protein and Peptide Letters. 17: 847-53. PMID 20156182 DOI: 10.2174/092986610791306661  0.565
2010 Mou J, Fang H, Liu Y, Shang L, Wang Q, Zhang L, Xu W. Design, synthesis and primary activity assay of bi- or tri-peptide analogues with the scaffold l-arginine as amino-peptidase N/CD13 inhibitors. Bioorganic & Medicinal Chemistry. 18: 887-95. PMID 19969464 DOI: 10.1016/J.Bmc.2009.11.036  0.467
2009 Liu Y, Shang L, Fang H, Zhu H, Mu J, Wang Q, Wang X, Yuan Y, Xu W. Design, synthesis, and preliminary studies of the activity of novel derivatives of N-cinnamoyl-L-aspartic acid as inhibitors of aminopeptidase N/CD13. Bioorganic & Medicinal Chemistry. 17: 7398-404. PMID 19782572 DOI: 10.1016/J.Bmc.2009.07.014  0.458
2009 Mou J, Fang H, Jing F, Wang Q, Liu Y, Zhu H, Shang L, Wang X, Xu W. Design, synthesis and primary activity evaluation of L-arginine derivatives as amino-peptidase N/CD13 inhibitors. Bioorganic & Medicinal Chemistry. 17: 4666-73. PMID 19454370 DOI: 10.1016/J.Bmc.2009.04.056  0.468
2009 Shang L, Fang H, Zhu H, Wang X, Wang Q, Mu J, Wang B, Kishioka S, Xu W. Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors. Bioorganic & Medicinal Chemistry. 17: 2775-84. PMID 19299146 DOI: 10.1016/J.Bmc.2009.02.034  0.575
2008 Shang L, Wang Q, Fang H, Mu J, Wang X, Yuan Y, Wang B, Xu W. Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN). Bioorganic & Medicinal Chemistry. 16: 9984-90. PMID 18996018 DOI: 10.1016/J.Bmc.2008.10.025  0.575
2008 Shang L, Maeda T, Xu W, Kishioka S. Evaluation of a novel aminopeptidase N inhibitor, in vitro, using two assay systems. Journal of Enzyme Inhibition and Medicinal Chemistry. 23: 198-205. PMID 18343904 DOI: 10.1080/14756360701515541  0.415
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