James F. Amatruda - Publications

Affiliations: 
Pediatrics University of Southern California, Los Angeles, CA, United States 

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kuo C, Amatruda JF. Seed becoming soil: A new paradigm of the Ewing sarcoma tumor microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37796143 DOI: 10.1158/1078-0432.CCR-23-2259  0.305
2023 Xu L, Pierce JL, Sanchez A, Chen KS, Shukla AA, Fustino NJ, Stuart SH, Bagrodia A, Xiao X, Guo L, Krailo MD, Shaikh F, Billmire DF, Pashankar F, Bestrashniy J, ... ... Amatruda JF, et al. Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence. Nature Communications. 14: 2636. PMID 37149691 DOI: 10.1038/s41467-023-38378-9  0.318
2023 Xu L, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhang Y, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Chen KS. Wilms tumor mutational subclasses converge to drive overexpression. Medrxiv : the Preprint Server For Health Sciences. PMID 36778325 DOI: 10.1101/2023.01.30.23285117  0.308
2023 Watson S, LaVigne CA, Xu L, Surdez D, Cyrta J, Calderon D, Cannon MV, Kent MR, Silvius KM, Kucinski JP, Harrison EN, Murchison W, Rakheja D, Tirode F, Delattre O, ... Amatruda JF, et al. VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis. Cell Reports. 42: 112013. PMID 36656711 DOI: 10.1016/j.celrep.2023.112013  0.302
2022 Vasileva E, Warren M, Triche TJ, Amatruda JF. Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth. Elife. 11. PMID 35285802 DOI: 10.7554/eLife.69734  0.345
2021 Ci B, Lin SY, Yao B, Luo D, Xu L, Krailo M, Murray MJ, Amatruda JF, Frazier AL, Xie Y. Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods in Molecular Biology (Clifton, N.J.). 2195: 263-275. PMID 32852769 DOI: 10.1007/978-1-0716-0860-9_17  0.344
2020 Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, ... ... Amatruda JF, et al. Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nature Communications. 11: 2423. PMID 32415069 DOI: 10.1038/S41467-020-16244-2  0.309
2020 Wiemels JL, Wang R, Feng Q, Clark CJ, Amatruda JF, Rubin E, Yee A, Morimoto LM, Metayer C, Ma X. Birth characteristics and risk of early-onset synovial sarcoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32245786 DOI: 10.1158/1055-9965.Epi-20-0093  0.305
2020 Chen KS, Desai K, Amatruda JF. Abstract PR01: Three-hit model of Wilms’ tumor formation reveals immunogenic transcriptional subtypes Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-Pr01  0.386
2020 Su XA, Ma D, Parsons JV, Replogle JM, Amatruda JF, Whittaker CA, Stegmaier K, Amon A. Abstract B52: Ewing sarcoma: A case study of clonal aneuploidy and DNA damage repair in pediatric cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B52  0.376
2020 Segal D, Chang B, Mazloom-Farsibaf H, Fiolka R, Amatruda J, Danuser G. Abstract PHB01: The zebrafish as a mechanical filter: Using zebrafish xenografts to model Ewing sarcoma metastasis in vivo Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Phb01  0.385
2019 Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, et al. GCNA Preserves Genome Integrity and Fertility Across Species. Developmental Cell. PMID 31839537 DOI: 10.1016/J.Devcel.2019.11.007  0.334
2019 Lafin JT, Singla N, Woldu SL, Lotan Y, Lewis CM, Majmudar K, Savelyeva A, Kapur P, Margulis V, Strand DW, Murray MJ, Amatruda JF, Bagrodia A. Serum MicroRNA-371a-3p Levels Predict Viable Germ Cell Tumor in Chemotherapy-naïve Patients Undergoing Retroperitoneal Lymph Node Dissection. European Urology. PMID 31699528 DOI: 10.1200/Jco.2020.38.6_Suppl.417  0.349
2019 Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF. Identification of testicular cancer driver genes by a cross-species comparative oncology approach. Andrology. PMID 31087453 DOI: 10.1111/Andr.12644  0.467
2019 Singla N, Lafin JT, Ghandour RA, Kaffenberger S, Amatruda JF, Bagrodia A. Genetics of testicular germ cell tumors. Current Opinion in Urology. PMID 31045925 DOI: 10.1097/Mou.0000000000000642  0.385
2019 Lafin JT, Bagrodia A, Woldu S, Amatruda JF. New insights into germ cell tumor genomics Journal of Andrology. 7: 507-515. PMID 30896089 DOI: 10.1111/Andr.12616  0.423
2019 Singla S, Wong J, Singla N, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda J, Lindsay Frazier A, Bagrodia A. Clinicopathologic predictors of outcomes in children with stage I germ cell tumours: A pooled post hoc analysis of trials from the Children’s Oncology Group European Urology Supplements. 18: 17-18. DOI: 10.1200/Jco.2020.38.6_Suppl.418  0.357
2019 O'Neill AF, Xia C, Krailo MD, Shaikh F, Pashankar FD, Billmire DF, Olson TA, Amatruda JF, Villaluna D, Malogolowkin MH, Rodriguez-Galindo C, Frazier AL. Alfa-feto protein (AFP) as a predictor of outcome for children with germ cell tumors: A report from the malignant germ cell international consortium. Journal of Clinical Oncology. 37: 10036-10036. DOI: 10.1200/Jco.2019.37.15_Suppl.10036  0.447
2019 Shaikh F, Stark DP, Dang H, Xia C, Krailo MD, Stenning SP, Pashankar FD, Rodriguez-Galindo C, Olson TA, Hale J, Depani S, Stoneham S, Nicholson J, Murray M, Amatruda JF, et al. Outcomes of adolescent males with extracranial malignant germ cell tumors compared with children and young adults: A report from the Malignant Germ Cell Tumors International Consortium (MaGIC) group. Journal of Clinical Oncology. 37: 10022-10022. DOI: 10.1200/Jco.2019.37.15_Suppl.10022  0.421
2019 Kendall GC, Watson S, Xu L, LaVigne C, Murchison W, Rakheja D, Tirode F, Delattre O, Amatruda J. Abstract 872: Genetic models reveal that the novelVGLL2-NCOA2fusion oncogene leverages embryonic programs for sarcomagenesis Cancer Research. 79: 872-872. DOI: 10.1158/1538-7445.Sabcs18-872  0.443
2018 Fonseca A, Xia C, Lorenzo AJ, Krailo M, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Billmire DF, Rodriguez-Galindo C, Frazier AL, Shaikh F. Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1800790. PMID 30576269 DOI: 10.1200/Jco.18.00790  0.396
2018 Williams LA, Pankratz N, Lane J, Krailo M, Roesler M, Richardson M, Lindsay Frazier A, Amatruda JF, Poynter JN. Klinefelter syndrome in males with germ cell tumors: A report from the children's oncology group. Cancer. PMID 30291793 DOI: 10.1002/Cncr.31667  0.368
2018 Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. Mutations in microRNA processing genes in Wilms tumors derepress the regulator . Genes & Development. PMID 30026293 DOI: 10.1101/Gad.313783.118  0.422
2018 Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX. Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes. Cell Reports. 24: 238-251. PMID 29972784 DOI: 10.1016/J.Celrep.2018.06.006  0.357
2018 Shah R, Xia C, Krailo M, Amatruda JF, Arul SG, Billmire DF, Brady WE, Covens A, Gershenson DM, Hale JP, Hurteau J, Murray MJ, Nicholson JC, Olson TA, Pashankar F, et al. Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecologic Oncology. PMID 29884437 DOI: 10.1016/J.Ygyno.2018.05.025  0.344
2018 Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. transgenic zebrafish models identify as a mediator of rhabdomyosarcoma tumorigenesis. Elife. 7. PMID 29869612 DOI: 10.7554/Elife.33800  0.43
2018 Frazier AL, Stoneham S, Rodriguez-Galindo C, Dang H, Xia C, Olson TA, Murray MJ, Amatruda JF, Shaikh F, Pashankar F, Billmire D, Krailo M, Stark D, Brougham MFH, Nicholson JC, et al. Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. European Journal of Cancer (Oxford, England : 1990). 98: 30-37. PMID 29859339 DOI: 10.1016/J.Ejca.2018.03.004  0.349
2018 Pierce JL, Frazier AL, Amatruda JF. Pediatric Germ Cell Tumors: A Developmental Perspective. Advances in Urology. 2018: 9059382. PMID 29515628 DOI: 10.1155/2018/9059382  0.429
2018 Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF. EGF Receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors. Molecular Cancer Therapeutics. PMID 29483210 DOI: 10.1158/1535-7163.Mct-17-0137  0.433
2018 Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, et al. Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. The Oncologist. 23: 272. PMID 29449513 DOI: 10.1634/Theoncologist.2014-0009Erratum  0.36
2018 Watson S, Kendall GC, Murchison WA, Delattre O, Tirode F, Amatruda JF. Abstract PR06: Functional genomics of CIC-DUX4 fusions in zebrafish recapitulates the spectrum of human CIC-rearranged cancers Omics a Journal of Integrative Biology. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr06  0.461
2018 Williams LA, Pankratz N, Lane J, Roesler M, Richardson M, Frazier AL, Amatruda J, Poynter JN. Abstract A25: Prevalence of Klinefelter syndrome among males aged 0-19 years diagnosed with germ cell tumors: A report from the Children’s Oncology Group Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-A25  0.321
2018 Williams LA, Mills L, Hooten AJ, Langer E, Roesler M, Frazier AL, Amatruda J, Poynter JN. Abstract 2064: Differences in methylation patterns by pediatric germ cell tumor histologic subtype Cancer Research. 78: 2064-2064. DOI: 10.1158/1538-7445.Am2018-2064  0.397
2017 Dicken BJ, Billmire DF, Krailo M, Xia C, Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Rescorla FJ, Egler RA, Ross JH, Rodriguez-Galindo C, Frazier AL. Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatric Blood & Cancer. PMID 29286555 DOI: 10.1002/Pbc.26913  0.41
2017 Woldu SL, Aydin AM, Rao AV, Hutchinson RC, Singla N, Clinton TN, Krabbe LM, Passoni NM, Raj GV, Miller DS, Amatruda JF, Sagalowsky AI, Lotan Y, Arriaga Y, Margulis V, et al. Differences at Presentation and Treatment of Testicular Cancer in Hispanic Men: Institutional and National Hospital-Based Analysis. Urology. PMID 29079210 DOI: 10.1016/J.Urology.2017.08.059  0.343
2017 Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM. Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. Current Biology : Cb. PMID 28966088 DOI: 10.1016/J.Cub.2017.08.036  0.318
2017 Marcotte EL, Pankratz N, Amatruda JF, Frazier AL, Krailo M, Davies S, Starr JR, Ching CL, Roesler M, Langer E, Hallstrom C, Hooten AJ, Poynter JN. Variants in BAK1, SPRY4, and GAB2 are Associated with Pediatric Germ Cell Tumors: A Report from the Children's Oncology Group. Genes, Chromosomes & Cancer. PMID 28295819 DOI: 10.1002/Gcc.22457  0.301
2017 Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Villaluna D, Krailo M, Billmire DF, Rescorla FJ, Egler RA, Dicken BJ, Ross JH, Schlatter M, Rodriguez-Galindo C, et al. Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016676544. PMID 28240974 DOI: 10.1200/Jco.2016.67.6544  0.354
2017 Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Randall RL, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD. C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells. Oncotarget. PMID 28148901 DOI: 10.18632/Oncotarget.14847  0.326
2017 Woldu SL, Amatruda JF, Bagrodia A. Testicular germ cell tumor genomics. Current Opinion in Urology. 27: 41-47. PMID 27584029 DOI: 10.1097/Mou.0000000000000347  0.38
2017 Gardiner JD, Huang X, Lazaris E, Jones K, Yap JT, Randall RL, Abegglen L, Amatruda J, Schiffman JD. Association of genomically unstable Ewing sarcoma tumors with HOTAIR overexpression and clinical outcome. Journal of Clinical Oncology. 35: 11035-11035. DOI: 10.1200/Jco.2017.35.15_Suppl.11035  0.372
2016 Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nature Medicine. PMID 27941793 DOI: 10.1038/Nm.4252  0.382
2016 Liao Z, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. Risk of Second Malignant Neoplasms in Women and Girls with Germ Cell Tumors. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 27864217 DOI: 10.1093/Annonc/Mdw609  0.308
2016 Lee E, Wei Y, Zou Z, Tucker K, Rakheja D, Levine B, Amatruda JF. Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Oncotarget. PMID 27655644 DOI: 10.18632/Oncotarget.12084  0.437
2016 Dranow DB, Hu K, Bird AM, Lawry ST, Adams MT, Sanchez A, Amatruda JF, Draper BW. Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish. Plos Genetics. 12: e1006323. PMID 27642754 DOI: 10.1371/Journal.Pgen.1006323  0.301
2016 Kendall GC, Amatruda JF. Zebrafish as a Model for the Study of Solid Malignancies. Methods in Molecular Biology (Clifton, N.J.). 1451: 121-42. PMID 27464805 DOI: 10.1007/978-1-4939-3771-4_9  0.433
2016 Shaikh F, Murray MJ, Amatruda JF, Coleman N, Nicholson JC, Hale JP, Pashankar F, Stoneham SJ, Poynter JN, Olson TA, Billmire DF, Stark D, Rodriguez-Galindo C, Frazier AL. Paediatric extracranial germ-cell tumours. The Lancet. Oncology. 17: e149-e162. PMID 27300675 DOI: 10.1016/S1470-2045(15)00545-8  0.331
2016 Sanchez A, Amatruda JF. Zebrafish Germ Cell Tumors. Advances in Experimental Medicine and Biology. 916: 479-94. PMID 27165367 DOI: 10.1007/978-3-319-30654-4_21  0.479
2016 Liao ZW, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. PMID 27152727 DOI: 10.1002/Cncr.30014  0.362
2016 Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, et al. The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget. PMID 26802024 DOI: 10.18632/Oncotarget.6937  0.374
2016 Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM. p53 genes function to restrain mobile elements. Genes & Development. 30: 64-77. PMID 26701264 DOI: 10.1101/Gad.266098.115  0.314
2016 Meade JC, Moore ZR, Stuart SH, Cholka A, Boriack RL, Xu J, Erdreich-Epstein A, Rakheja D, Boothman DA, Amatruda JF, Laetsch TW. Abstract B39: NQO1 as a therapeutic target for atypical teratoid/ rhabdoid tumor Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B39  0.415
2016 Budhipramono A, Rakheja D, Chen KS, Fustino N, Shukla A, Wickiser J, Laetsch T, Amatruda JF. Abstract B03: EGFR and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B03  0.403
2016 Chen KS, Rakheja D, Liu Y, Shukla AA, Mendell JT, Amatruda JF. Abstract IA12: Mechanisms of tumorigenesis due to somatic mutations in DICER1 and DROSHA in childhood kidney cancers Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia12  0.372
2016 Kendall G, Watson S, Xu L, Tirode F, Delattre O, Amatruda J. Abstract NG03: Zebrafish models of PAX3-FOXO1 pathogenesis reveal novel targets in human rhabdomyosarcoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng03  0.416
2016 Marcotte EL, Pankratz N, Amatruda J, Frazier AL, Krailo M, Davies S, Starr J, Langer E, Hallstrom C, Hooten A, Poynter JN. Abstract LB-374: Variants in BAK1 and SPRY4 are associated with pediatric germ cell tumors Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-374  0.362
2016 Watson S, Kendall G, Delattre O, Tirode F, Amatruda JF. Abstract 4190: Expression of a human CIC-DUX4 fusion is sufficient to induce malignant small round blue cell tumors in zebrafish: a new model of CIC-DUX4 sarcoma for translational research Cancer Research. 76: 4190-4190. DOI: 10.1158/1538-7445.Am2016-4190  0.467
2015 Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, ... Amatruda JF, et al. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nature Communications. 6: 8891. PMID 26573325 DOI: 10.1038/Ncomms9891  0.364
2015 Pashankar F, Hale JP, Dang H, Krailo M, Brady WE, Rodriguez-Galindo C, Nicholson JC, Murray MJ, Bilmire DF, Stoneham S, Arul GS, Olson TA, Stark D, Shaikh F, Amatruda JF, et al. Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. PMID 26485622 DOI: 10.1002/Cncr.29732  0.339
2015 Olson TA, Murray MJ, Rodriguez-Galindo C, Nicholson JC, Billmire DF, Krailo MD, Dang HM, Amatruda JF, Thornton CM, Arul GS, Stoneham SJ, Pashankar F, Stark D, Shaikh F, Gershenson DM, et al. Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 3018-28. PMID 26304902 DOI: 10.1200/Jco.2014.60.5337  0.393
2015 Rescorla FJ, Ross JH, Billmire DF, Dicken BJ, Villaluna D, Davis MM, Krailo M, Cullen JW, Olson TA, Egler RA, Amatruda JF, Rodrigues-Galindo C, Frazier AL. Surveillance after initial surgery for Stage I pediatric and adolescent boys with malignant testicular germ cell tumors: Report from the Children's Oncology Group. Journal of Pediatric Surgery. 50: 1000-3. PMID 25812445 DOI: 10.1016/J.Jpedsurg.2015.03.026  0.394
2015 Frazier AL, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray MJ, Amatruda JF, Thornton C, Arul GS, Billmire D, Shaikh F, Pashankar F, Stoneham S, Krailo M, Nicholson JC. Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 195-201. PMID 25452439 DOI: 10.1200/Jco.2014.58.3369  0.403
2015 Moore ZR, Stuart S, Cholka A, Venkataraman A, Xu J, Erdreich-Epstein A, Rakheja D, Boothman DA, Amatruda JF, Laetsch TW. Abstract 1613: β-lapachone: a novel targeted therapy for atypical teratoid rhabdoid tumors (ATRTs) Cancer Research. 75: 1613-1613. DOI: 10.1158/1538-7445.Am2015-1613  0.314
2014 Aloisio GM, Nakada Y, Saatcioglu HD, Peña CG, Baker MD, Tarnawa ED, Mukherjee J, Manjunath H, Bugde A, Sengupta AL, Amatruda JF, Cuevas I, Hamra FK, Castrillon DH. PAX7 expression defines germline stem cells in the adult testis. The Journal of Clinical Investigation. 124: 3929-44. PMID 25133429 DOI: 10.1172/Jci75943  0.345
2014 Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, et al. Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. The Oncologist. 19: 689-92. PMID 24899644 DOI: 10.1634/Theoncologist.2014-0009  0.412
2014 Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 10: 572-87. PMID 24441423 DOI: 10.4161/Auto.27649  0.302
2014 Laetsch TW, Kumar K, Rakheja D, Wickiser JE, Rodriguez-Galindo C, Frazier AL, Amatruda J. A phase II study of sirolimus and erlotinib in recurrent/refractory germ cell tumors. Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.Tps2638  0.441
2014 Shaikh F, Dang H, Krailo MD, Hale J, Nicholson J, Rodriguez-Galindo C, Olson TA, Murray M, Amatruda J, Thornton C, Arul S, Billmire D, Frazier AL. Postrecurrence survival for pediatric extracranial malignant germ cell tumors: A report from the Malignant Germ Cell Tumors International Collaborative (MaGIC) Group. Journal of Clinical Oncology. 32: 10074-10074. DOI: 10.1200/Jco.2014.32.15_Suppl.10074  0.385
2014 Rakheja D, Chen KS, Liu Y, Chang T, Shukla AA, Malter J, Mendell JT, Amatruda JF. Abstract LB-204: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis in Wilms tumors Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-A22  0.383
2013 Amatruda JF, Ross JA, Christensen B, Fustino NJ, Chen KS, Hooten AJ, Nelson H, Kuriger JK, Rakheja D, Frazier AL, Poynter JN. DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. Bmc Cancer. 13: 313. PMID 23806198 DOI: 10.1186/1471-2407-13-313  0.371
2013 Chen KS, Amatruda JF. A big catch for germ cell tumour research. Plos Genetics. 9: e1003481. PMID 23593043 DOI: 10.1371/Journal.Pgen.1003481  0.419
2013 Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G. Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatric Blood & Cancer. 60: 1016-21. PMID 23255219 DOI: 10.1002/Pbc.24428  0.419
2013 Shukla AA, Khokhar S, Amatruda JF, Rakheja D. Abstract 5046: Protein tyrosine phosphatase epsilon (PTPE), a candidate tumor-suppressor in Wilms tumors of childhood, can regulate PI3K/AKT/mTOR pathway. Cancer Research. 73: 5046-5046. DOI: 10.1158/1538-7445.Am2013-5046  0.431
2012 Verduzco D, Dovey JS, Shukla AA, Kodym E, Skaug BA, Amatruda JF. Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development. Molecular Cancer Research : McR. 10: 1451-61. PMID 22986406 DOI: 10.1158/1541-7786.Mcr-12-0072  0.365
2012 Frazier AL, Weldon C, Amatruda J. Fetal and neonatal germ cell tumors. Seminars in Fetal & Neonatal Medicine. 17: 222-230. PMID 22647545 DOI: 10.1016/J.Siny.2012.05.004  0.431
2012 Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, et al. Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. The Journal of Biological Chemistry. 287: 23246-54. PMID 22593577 DOI: 10.1074/Jbc.M112.372029  0.308
2012 Moro E, Ozhan-Kizil G, Mongera A, Beis D, Wierzbicki C, Young RM, Bournele D, Domenichini A, Valdivia LE, Lum L, Chen C, Amatruda JF, Tiso N, Weidinger G, Argenton F. In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Developmental Biology. 366: 327-40. PMID 22546689 DOI: 10.1016/J.Ydbio.2012.03.023  0.332
2012 Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Disease Models & Mechanisms. 5: 95-106. PMID 21979944 DOI: 10.1242/Dmm.007401  0.451
2011 Neumann JC, Lillard K, Damoulis V, Amatruda JF. Zebrafish models of germ cell tumor. Methods in Cell Biology. 105: 3-24. PMID 21951524 DOI: 10.1016/B978-0-12-381320-6.00001-1  0.458
2011 Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L, Margraf L, Rakheja D, Amatruda JF. Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 108: 13153-8. PMID 21775673 DOI: 10.1073/Pnas.1102311108  0.431
2011 Fustino N, Rakheja D, Ateek CS, Neumann JC, Amatruda JF. Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours. International Journal of Andrology. 34: e218-33. PMID 21696393 DOI: 10.1111/J.1365-2605.2011.01186.X  0.329
2011 Verduzco D, Amatruda JF. Analysis of cell proliferation, senescence, and cell death in zebrafish embryos. Methods in Cell Biology. 101: 19-38. PMID 21550438 DOI: 10.1016/B978-0-12-387036-0.00002-5  0.359
2011 Paulson V, Chandler G, Rakheja D, Galindo RL, Wilson K, Amatruda JF, Cameron S. High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis. Genes, Chromosomes & Cancer. 50: 397-408. PMID 21412928 DOI: 10.1002/Gcc.20864  0.406
2011 Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. Science Signaling. 4: ra4. PMID 21266715 DOI: 10.1126/Scisignal.2001225  0.351
2011 Fustino NJ, Rakheja D, Amatruda JF. BMP signaling activity in pediatric germ cell tumors. Journal of Clinical Oncology. 29: 9538-9538. DOI: 10.1200/Jco.2011.29.15_Suppl.9538  0.407
2011 Poynter JN, Christensen B, Nelson HH, Amatruda JF, Frazier AL, Ross JA. Abstract 872: DNA methylation patterns distinguish histologic subtypes of pediatric germ cell tumors Cancer Research. 71: 872-872. DOI: 10.1158/1538-7445.Am2011-872  0.436
2009 Neumann JC, Dovey JS, Chandler GL, Carbajal L, Amatruda JF. Identification of a heritable model of testicular germ cell tumor in the zebrafish. Zebrafish. 6: 319-27. PMID 20047465 DOI: 10.1089/Zeb.2009.0613  0.48
2009 Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, ... ... Amatruda JF, et al. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Molecular and Cellular Biology. 29: 5911-22. PMID 19704007 DOI: 10.1128/Mcb.00558-09  0.412
2009 Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature Chemical Biology. 5: 100-7. PMID 19125156 DOI: 10.1038/Nchembio.137  0.324
2009 Leacock SW, Basse AN, Chandler GL, Kirk A, Amatruda JF. Abstract B36: The Ewing's sarcoma fusion oncogene EWS-FLI1 induces tumors and developmental phenotypes in zebrafish Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B36  0.472
2008 Amatruda JF, Patton EE. Genetic models of cancer in zebrafish. International Review of Cell and Molecular Biology. 271: 1-34. PMID 19081540 DOI: 10.1016/S1937-6448(08)01201-X  0.369
2007 Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE. The INT6 cancer gene and MEK signaling pathways converge during zebrafish development. Plos One. 2: e959. PMID 17895999 DOI: 10.1371/Journal.Pone.0000959  0.403
2007 Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & Development. 21: 55-9. PMID 17210788 DOI: 10.1101/Gad.1470407  0.391
2007 Amatruda J, Neumann J, Lillard K, Carbajal L. Germline Development And Germ Cell Tumors In The Zebrafish System Biology of Reproduction. 77: 72-72. DOI: 10.1093/Biolreprod/77.S1.72B  0.44
2005 Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology. 1: 366-70. PMID 16372403 DOI: 10.1038/Nchembio749  0.351
2005 Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 102: 13194-9. PMID 16150706 DOI: 10.1073/Pnas.0506583102  0.405
2005 Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current Biology : Cb. 15: 249-54. PMID 15694309 DOI: 10.1016/J.Cub.2005.01.031  0.318
2004 Shepard JL, Stern HM, Pfaff KL, Amatruda JF. Analysis of the cell cycle in zebrafish embryos. Methods in Cell Biology. 76: 109-25. PMID 15602874 DOI: 10.1016/S0091-679X(04)76007-0  0.358
2000 Amatruda JF, Zon LI. Dissecting hematopoiesis and disease using the zebrafish. Developmental Biology. 216: 1-15. PMID 10588859 DOI: 10.1006/Dbio.1999.9462  0.374
1998 Amatruda JF, Tran K, Mantel M, Singer S, Demetri G. Diagnosis in oncology. Askin tumor. Journal of Clinical Oncology. 16: 1997-1998. PMID 9586920 DOI: 10.1200/Jco.1998.16.5.1997  0.359
1992 Amatruda JF, Cooper JA. Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein. The Journal of Cell Biology. 117: 1067-76. PMID 1315784 DOI: 10.1083/Jcb.117.5.1067  0.449
1991 Cooper JA, Caldwell JE, Gattermeir DJ, Torres MA, Amatruda JF, Casella JF. Variant cDNAs encoding proteins similar to the α subunit of chicken CapZ Cell Motility and the Cytoskeleton. 18: 204-214. PMID 1711931 DOI: 10.1002/Cm.970180306  0.434
1990 Amatruda JF, Cannon JF, Tatchell K, Hug C, Cooper JA. Disruption of the actin cytoskeleton in yeast capping protein mutants. Nature. 344: 352-4. PMID 2179733 DOI: 10.1038/344352A0  0.495
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