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Malcolm L. Gefter - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
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62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1992 Wang Y, Smith JA, Kamradt T, Gefter ML, Perkins DL. Silencing of immunodominant epitopes by contiguous sequences in complex synthetic peptides Cellular Immunology. 143: 284-297. PMID 1380894 DOI: 10.1016/0008-8749(92)90026-L  0.305
1990 Wysocki LJ, Gefter M. The molecular basis of a VH gene polymorphism that determines the expression of a major idiotype. Molecular Immunology. 26: 1143-50. PMID 2633048 DOI: 10.1016/0161-5890(89)90058-8  0.347
1990 Wysocki LJ, Gefter ML, Margolies MN. Parallel evolution of antibody variable regions by somatic processes: Consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversion Journal of Experimental Medicine. 172: 315-323. PMID 2358780 DOI: 10.1084/Jem.172.1.315  0.311
1990 Chang MDY, Kowal C, Marzullo LR, Briner TJ, Gefter ML, Diamond B. Genetic recombination in the α2 domain of the Eα chain yields an Ed molecule with altered T cell activation European Journal of Immunology. 20: 2571-2576. PMID 2148522 DOI: 10.1002/Eji.1830201207  0.314
1990 Ria F, Chan BMC, Scherer MT, Smith JA, Gefter ML. Immunological activity of covalently linked T-cell epitopes Nature. 343: 381-383. PMID 1689012 DOI: 10.1038/343381A0  0.311
1987 Wysocki LJ, Gridley T, Huang S, Grandea AG, Gefter ML. Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p-azophenylarsonate. The Journal of Experimental Medicine. 166: 1-11. PMID 3036994 DOI: 10.1084/Jem.166.1.1  0.317
1986 Wysocki L, Manser T, Gefter ML. Somatic evolution of variable region structures during an immune response Proceedings of the National Academy of Sciences of the United States of America. 83: 1847-1851. PMID 3485290 DOI: 10.1073/Pnas.83.6.1847  0.311
1986 Sharon J, Gefter ML, Manser T, Ptashne M. Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody. Proceedings of the National Academy of Sciences of the United States of America. 83: 2628-31. PMID 3085101 DOI: 10.1073/Pnas.83.8.2628  0.348
1986 Naparstek Y, André-Schwartz J, Manser T, Wysocki LJ, Breitman L, Stollar BD, Gefter M, Schwartz RS. A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus. Journal of Experimental Medicine. 164: 614-626. PMID 3014041 DOI: 10.1084/Jem.164.2.614  0.405
1986 Daley MJ, Nakamura M, Gefter ML. Functional and biochemical characterization of a secreted I-J(+) suppressor factor that binds to immunoglobulin Journal of Experimental Medicine. 163: 1415-1432. PMID 2940311 DOI: 10.1084/Jem.163.6.1415  0.326
1984 Gefter ML, Margolies MN, Near RI, Wysocki LJ. Analysis of the anti-azobenzenearsonate response at the molecular level. Annales D'Immunologie. 135: 17-30. PMID 6712160 DOI: 10.1016/S0769-2625(84)80007-0  0.304
1984 Nakamura M, Manser T, Pearson GDN, Daley MJ, Gefter ML. Effect of IFN-γ on the immune response in vivo and on gene expression in vitro Nature. 307: 381-382. PMID 6420707 DOI: 10.1038/307381A0  0.313
1984 Sharon J, Gefter ML, Manser T. Expression of a V(H)C(κ) chimaeric protein in mouse myeloma cells Nature. 309: 364-367. PMID 6328310 DOI: 10.1038/309364A0  0.312
1984 Near RI, Juszczak EC, Huang SY, Sicari SA, Margolies MN, Gefter ML. Expression and rearrangement of homologous immunoglobulin VH genes in two mouse strains. Proceedings of the National Academy of Sciences of the United States of America. 81: 2167-71. PMID 6326109 DOI: 10.1073/Pnas.81.7.2167  0.374
1983 Rothstein TL, Gefter ML. Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera Molecular Immunology. 20: 161-168. PMID 6843553 DOI: 10.1016/0161-5890(83)90127-X  0.328
1983 Siekevitz M, Huang SY, Gefter ML. The genetic basis of antibody production: a single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse. European Journal of Immunology. 13: 123-32. PMID 6403356 DOI: 10.1002/Eji.1830130207  0.355
1983 Rothstein TL, Margolies MN, Gefter ML, Marshak Rothstein A. Fine-specificity of idiotope suppression in the A/J anti-azophenylarsonate response Journal of Experimental Medicine. 157: 795-800. PMID 6185619 DOI: 10.1084/Jem.157.2.795  0.315
1982 Siekevitz M, Gefter ML, Brodeur P, Riblet R, Marshak-Rothstein A. The genetic basis of antibody production: The dominant anti-arsonate idiotype response of the strain A mouse European Journal of Immunology. 12: 1023-1032. PMID 6186498 DOI: 10.1002/Eji.1830121208  0.388
1982 Manley JL, Sharp PA, Gefter ML. Rna synthesis in isolated nuclei processing of adenovirus serotype 2 late messenger rna precursors. Journal of Molecular Biology. 159: 581-99. PMID 6183434 DOI: 10.1016/0022-2836(82)90102-4  0.506
1981 Sharp PA, Manley J, Fire A, Gefter M. Regulation of adenovirus mRNA synthesis. Annals of the New York Academy of Sciences. 354: 1-15. PMID 7013617 DOI: 10.1111/J.1749-6632.1980.Tb27954.X  0.517
1981 Margolies MN, Marshak-Rothstein A, Gefter ML. Structural diversity among anti-p-azophenylarsonate monoclonal antibodies from A/J mice: Comparison of Id- and Id+ sequences Molecular Immunology. 18: 1065-1077. PMID 6801478 DOI: 10.1016/0161-5890(81)90022-5  0.302
1981 Spritz RA, Jagadeeswaran P, Choudary PV, Biro PA, Elder JT, deRiel JK, Manley JL, Gefter ML, Forget BG, Weissman SM. Base substitution in an intervening sequence of a beta+-thalassemic human globin gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 2455-9. PMID 6264477 DOI: 10.1073/Pnas.78.4.2455  0.482
1981 Ponte PA, Siekevitz M, Schwartz RC, Gefter ML, Sonenshein GE. Transcription of immunoglobulin heavy-chain sequences from the excluded allele Nature. 291: 594-596. PMID 6264313 DOI: 10.1038/291594A0  0.328
1981 Bothwell ALM, Paskind M, Schwartz RC, Sonenshein GE, Gefter ML, Baltimore D. Dual expression of λ genes in the MOPC-315 plasmacytoma Nature. 290: 65-67. PMID 6259534 DOI: 10.1038/290065A0  0.389
1981 Manley JL, Gefter ML. Transcription of mammalian genes in vitro. Gene Amplification and Analysis. 2: 369-82. PMID 6101055  0.425
1980 Manley JL, Fire A, Cano A, Sharp PA, Gefter ML. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proceedings of the National Academy of Sciences of the United States of America. 77: 3855-9. PMID 6933441 DOI: 10.1073/Pnas.77.7.3855  0.601
1980 Marshak-Rothstein A, Siekevitz M, Margolies MN, Mudgett-Hunter M, Gefter ML. Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice Proceedings of the National Academy of Sciences of the United States of America. 77: 1120-1124. PMID 6767242 DOI: 10.1073/Pnas.77.2.1120  0.344
1980 Proudfoot NJ, Shander MH, Manley JL, Gefter ML, Maniatis T. Structure and in vitro transcription of human globin genes. Science (New York, N.Y.). 209: 1329-36. PMID 6158093 DOI: 10.1126/Science.6158093  0.508
1979 Mory Y, Gefter M. RNA synthesis in isolated nuclei: the use of mercurated nucleotides. Nucleic Acids Research. 5: 3899-912. PMID 724503 DOI: 10.1093/Nar/5.10.3899  0.323
1979 Manley JL, Sharp PA, Gefter ML. RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. Journal of Molecular Biology. 135: 171-97. PMID 529286 DOI: 10.1016/0022-2836(79)90346-2  0.519
1979 Manley JL, Sharp PA, Gefter ML. RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proceedings of the National Academy of Sciences of the United States of America. 76: 160-4. PMID 284328 DOI: 10.1073/Pnas.76.1.160  0.511
1979 Yarranton GT, Das RH, Gefter ML. Enzyme-catalyzed DNA unwinding. A DNA-dependent ATPase from E. coli Journal of Biological Chemistry. 254: 11997-12001. PMID 227886  0.339
1979 Yarranton GT, Gefter ML. Enzyme-catalyzed DNA unwinding: Studies on Escherichia coli rep protein Proceedings of the National Academy of Sciences of the United States of America. 76: 1658-1662. PMID 221901 DOI: 10.1073/Pnas.76.4.1658  0.463
1977 Margulies DH, Cieplinski W, Dharmgrongartama B, Gefter ML, Morrison SL, Kelly T, Scharff MD. Regulation of immunoglobulin expression in mouse myeloma cells. Cold Spring Harbor Symposia On Quantitative Biology. 41: 781-91. PMID 408077 DOI: 10.1101/Sqb.1977.041.01.089  0.302
1976 Ptashne M, Gilbert W, Baltimore D, Gefter M, Steitz J, Bishop M, Guthrie C, Boyer H, Sobell H, Abelson J, Alberts B. The "sunday seminar". Science (New York, N.Y.). 191: 245. PMID 17832131 DOI: 10.1126/Science.191.4224.245  0.362
1976 Ray R, Capon D, Gefter M. "Distinguishable steps in the enzymatic synthesis of bacteriophage phiX174 replicative form in vitro". Biochemical and Biophysical Research Communications. 70: 506-12. PMID 779776 DOI: 10.1016/0006-291X(76)91075-5  0.435
1976 Sherman LA, Gefter ML. Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II Journal of Molecular Biology. 103: 61-76. PMID 60493 DOI: 10.1016/0022-2836(76)90052-8  0.49
1975 Molineux IJ, Pauli A, Gefter ML. Physical studies of the interaction between the escherichia coli DNA binding protein and nucleic acids Nucleic Acids Research. 2: 1821-1838. PMID 1103088 DOI: 10.1093/Nar/2.10.1821  0.665
1975 Bikoff EK, LaRue BF, Gefter ML. In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities Journal of Biological Chemistry. 250: 6248-6255. PMID 1099090  0.341
1975 Gefter ML. DNA replication. Annual Review of Biochemistry. 44: 45-78. PMID 1094915  0.334
1975 Molineux IJ, Gefter ML. Properties of the Escherichia coli DNA-binding (unwinding) protein interaction with nucleolytic enzymes and DNA Journal of Molecular Biology. 98: 811-825. PMID 172646 DOI: 10.1016/S0022-2836(75)80012-X  0.691
1974 Molineux IJ, Gefter ML. Properties of the Escherichia coli DNA binding (unwinding) protein: interaction with DNA polymerase and DNA Proceedings of the National Academy of Sciences of the United States of America. 71: 3858-3862. PMID 4610564 DOI: 10.1073/Pnas.71.10.3858  0.693
1974 Molineux IJ, Friedman S, Gefter ML. Purification and properties of the Escherichia coli deoxyribonucleic acid unwinding protein. Effects on deoxyribonucleic acid synthesis in vitro Journal of Biological Chemistry. 249: 6090-6098. PMID 4608147  0.579
1974 Gefter ML. DNA polymerases II and 3 of Escherichia coli. Progress in Nucleic Acid Research and Molecular Biology. 14: 101-15. PMID 4602490 DOI: 10.1016/S0079-6603(08)60206-8  0.487
1974 Kornberg T, Gefter ML. Deoxyribonucleic acid polymerase 3 (Escherichia coli K12). Methods in Enzymology. 29: 22-6. PMID 4211910 DOI: 10.1016/0076-6879(74)29005-0  0.697
1974 Gefter ML. DNA Polymerases II and III of Escherichia coli Progress in Nucleic Acid Research and Molecular Biology. 14: 101-115. DOI: 10.1016/S0079-6603(08)60206-8  0.332
1974 Kornberg T, Gefter ML. [3] Deoxyribonucleic acid polymerase III (Escherichia coli K12) Methods in Enzymology. 29: 22-26. DOI: 10.1016/0076-6879(74)29005-0  0.57
1973 Manley J, Reiness G, Zubay G, Gefter ML. Cell-free synthesis of SU+ III tyrosyl transfer RNA: Characterization of the 4S product Archives of Biochemistry and Biophysics. 157: 50-54. PMID 4716962 DOI: 10.1016/0003-9861(73)90388-3  0.558
1973 Reuben RC, Gefter ML. A DNA binding protein induced by bacteriophage T7 Proceedings of the National Academy of Sciences of the United States of America. 70: 1846-1850. PMID 4578445 DOI: 10.1073/Pnas.70.6.1846  0.481
1973 Hirota Y, Gefter M, Mindich L. A mutant of Escherichia coli defective in DNA polymerase II activity. Proceedings of the National Academy of Sciences of the United States of America. 69: 3238-42. PMID 4564210 DOI: 10.1073/Pnas.69.11.3238  0.373
1973 Yang S, Reinitz ER, Gefter ML. Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA Archives of Biochemistry and Biophysics. 157: 55-62. PMID 4352057 DOI: 10.1016/0003-9861(73)90389-5  0.326
1972 Zubay G, Cheong L, Gefter M. DNA-directed cell-free synthesis of biologically active transfer RNA: su + 3 tyrosyl-tRNA. Proceedings of the National Academy of Sciences of the United States of America. 68: 2195-7. PMID 4943792 DOI: 10.1073/Pnas.68.9.2195  0.419
1972 Sigal N, Delius H, Kornberg T, Gefter ML, Alberts B. A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 69: 3537-3541. PMID 4566449 DOI: 10.1073/Pnas.69.12.3537  0.698
1972 Kornberg T, Gefter ML. Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III. The Journal of Biological Chemistry. 247: 5369-75. PMID 4560196  0.332
1972 Gefter ML, Molineux IJ, Kornberg T, Khorana HG. Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II. The Journal of Biological Chemistry. 247: 3321-6. PMID 4337512  0.581
1971 Gefter ML, Hirota Y, Kornberg T, Wechsler JA, Barnoux C. Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 68: 3150-3. PMID 4943556 DOI: 10.1073/Pnas.68.12.3150  0.683
1971 Kornberg T, Gefter ML. Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 68: 761-4. PMID 4927672 DOI: 10.1073/Pnas.68.4.761  0.684
1970 Kornberg T, Gefter ML. DNA synthesis in cell-free extracts of a DNA polymerase-defective mutant. Biochemical and Biophysical Research Communications. 40: 1348-55. PMID 4933688 DOI: 10.1016/0006-291X(70)90014-8  0.686
1968 Becker A, Lyn G, Gefter M, Hurwitz J. The enzymatic repair of DNA, II. Characterization of phage-induced sealase. Proceedings of the National Academy of Sciences of the United States of America. 58: 1996-2003. PMID 4295584 DOI: 10.1073/Pnas.58.5.1996  0.581
1967 Gefter ML, Becker A, Hurwitz J. The enzymatic repair of DNA. I. Formation of circular lambda-DNA. Proceedings of the National Academy of Sciences of the United States of America. 58: 240-7. PMID 5341057 DOI: 10.1073/Pnas.58.1.240  0.587
1967 Gold M, Gefter M, Hausmann R, Hurwitz J. Methylation of DNA. The Journal of General Physiology. 49: 5-28. PMID 5338563 DOI: 10.1085/Jgp.49.6.5  0.545
1967 Hurwitz J, Becker A, Gefter ML, Gold M. Enzymatic reactions at termini of DNA. Journal of Cellular Physiology. 70: Suppl:181-99. PMID 4295791 DOI: 10.1002/Jcp.1040700413  0.595
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