Francesca Luca, PhD - Publications

Affiliations: 
2003-2006 Biology University of Calabria, Italy 
 2006-2011 Human Genetics University of Chicago, Chicago, IL 
 2012- Center for Molecular Medicine and Genetics Wayne State University, Detroit, MI, United States 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Boye C, Kalita CA, Findley AS, Alazizi A, Wei J, Wen X, Pique-Regi R, Luca F. Characterization of caffeine response regulatory variants in vascular endothelial cells. Elife. 13. PMID 38334359 DOI: 10.7554/eLife.85235  0.835
2023 Wei J, Lambert TY, Valada A, Patel N, Walker K, Lenders J, Schmidt CJ, Iskhakova M, Alazizi A, Mair-Meijers H, Mash DC, Luca F, Pique-Regi R, Bannon MJ, Akbarian S. Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder. Nature Communications. 14: 5610. PMID 37699936 DOI: 10.1038/s41467-023-41455-8  0.662
2023 Aquino Y, Bisiaux A, Li Z, O'Neill M, Mendoza-Revilla J, Merkling SH, Kerner G, Hasan M, Libri V, Bondet V, Smith N, de Cevins C, Ménager M, Luca F, Pique-Regi R, et al. Dissecting human population variation in single-cell responses to SARS-CoV-2. Nature. PMID 37558883 DOI: 10.1038/s41586-023-06422-9  0.66
2023 Resztak JA, Wei J, Zilioli S, Sendler E, Alazizi A, Mair-Meijers HE, Wu P, Wen X, Slatcher RB, Zhou X, Luca F, Pique-Regi R. Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution. Genome Research. PMID 37442575 DOI: 10.1101/gr.276765.122  0.718
2023 Wei J, Lambert TY, Valada A, Patel N, Walker K, Lenders J, Schmidt CJ, Iskhakova M, Alazizi A, Mair-Meijers H, Mash DC, Luca F, Pique-Regi R, Bannon MJ, Akbarian S. Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases. Biorxiv : the Preprint Server For Biology. PMID 36945611 DOI: 10.1101/2023.03.07.531400  0.66
2023 Resztak JA, Choe J, Nirmalan S, Wei J, Bruinsma J, Houpt R, Alazizi A, Mair-Meijers HE, Wen X, Slatcher RB, Zilioli S, Pique-Regi R, Luca F. Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma. Nature Communications. 14: 230. PMID 36646693 DOI: 10.1038/s41467-022-35742-z  0.678
2023 Okamoto J, Wang L, Yin X, Luca F, Pique-Regi R, Helms A, Im HK, Morrison J, Wen X. Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits. American Journal of Human Genetics. 110: 44-57. PMID 36608684 DOI: 10.1016/j.ajhg.2022.12.002  0.698
2022 Hukku A, Sampson MG, Luca F, Pique-Regi R, Wen X. Analyzing and reconciling colocalization and transcriptome-wide association studies from the perspective of inferential reproducibility. American Journal of Human Genetics. 109: 825-837. PMID 35523146 DOI: 10.1016/j.ajhg.2022.04.005  0.697
2022 Resztak JA, Wei J, Zilioli S, Sendler E, Alazizi A, Mair-Meijers HE, Wu P, Slatcher RB, Zhou X, Luca F, Pique-Regi R. Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution. Biorxiv : the Preprint Server For Biology. PMID 35313584 DOI: 10.1101/2021.09.30.462672  0.718
2021 Muehlbauer AL, Richards AL, Alazizi A, Burns MB, Gomez A, Clayton JB, Petrzelkova K, Cascardo C, Resztak J, Wen X, Pique-Regi R, Luca F, Blekhman R. Interspecies variation in hominid gut microbiota controls host gene regulation. Cell Reports. 37: 110057. PMID 34818542 DOI: 10.1016/j.celrep.2021.110057  0.789
2021 Findley AS, Zhang X, Boye C, Lin YL, Kalita CA, Barreiro L, Lohmueller KE, Pique-Regi R, Luca F. A signature of Neanderthal introgression on molecular mechanisms of environmental responses. Plos Genetics. 17: e1009493. PMID 34570765 DOI: 10.1371/journal.pgen.1009493  0.838
2021 Resztak JA, Farrell AK, Mair-Meijers H, Alazizi A, Wen X, Wildman DE, Zilioli S, Slatcher RB, Pique-Regi R, Luca F. Psychosocial experiences modulate asthma-associated genes through gene-environment interactions. Elife. 10. PMID 34142656 DOI: 10.7554/eLife.63852  0.671
2021 Findley AS, Monziani A, Richards AL, Rhodes K, Ward MC, Kalita CA, Alazizi A, Pazokitoroudi A, Sankararaman S, Wen X, Lanfear DE, Pique-Regi R, Gilad Y, Luca F. Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions. Elife. 10. PMID 33988505 DOI: 10.7554/eLife.67077  0.83
2020 Hukku A, Pividori M, Luca F, Pique-Regi R, Im HK, Wen X. Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations. American Journal of Human Genetics. PMID 33308443 DOI: 10.1016/j.ajhg.2020.11.012  0.664
2020 Zhang Y, Quick C, Yu K, Barbeira A, Luca F, Pique-Regi R, Kyung Im H, Wen X. PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis. Genome Biology. 21: 232. PMID 32912253 DOI: 10.1186/S13059-020-02026-Y  0.701
2020 Pique-Regi R, Romero R, Tarca AL, Luca F, Xu Y, Alazizi A, Leng Y, Hsu CD, Gomez-Lopez N. Does the human placenta express the canonical cell entry mediators for SARS-CoV-2? Elife. 9. PMID 32662421 DOI: 10.7554/Elife.58716  0.636
2020 Talreja J, Bauerfeld C, Sendler E, Pique-Regi R, Luca F, Samavati L. Derangement of Metabolic and Lysosomal Gene Profiles in Response to Dexamethasone Treatment in Sarcoidosis. Frontiers in Immunology. 11: 779. PMID 32477331 DOI: 10.3389/Fimmu.2020.00779  0.684
2020 Pique-Regi R, Romero R, Tarca AL, Luca F, Xu Y, Alazizi A, Leng Y, Hsu C, Gomez-Lopez N. Author response: Does the human placenta express the canonical cell entry mediators for SARS-CoV-2? Elife. DOI: 10.7554/Elife.58716.Sa2  0.34
2019 Pique-Regi R, Romero R, Tarca AL, Sendler ED, Xu Y, Garcia-Flores V, Leng Y, Luca F, Hassan SS, Gomez-Lopez N. Single cell transcriptional signatures of the human placenta in term and preterm parturition. Elife. 8. PMID 31829938 DOI: 10.7554/Elife.52004  0.649
2019 Hukku A, Quick C, Luca F, Pique-Regi R, Wen X. BAGSE: A Bayesian Hierarchical Model Approach for Gene Set Enrichment Analysis. Bioinformatics (Oxford, England). PMID 31702789 DOI: 10.1093/Bioinformatics/Btz831  0.698
2019 Findley AS, Richards AL, Petrini C, Alazizi A, Doman E, Shanku AG, Davis GO, Hauff N, Sorokin Y, Wen X, Pique-Regi R, Luca F. Interpreting Coronary Artery Disease Risk Through Gene-Environment Interactions in Gene Regulation. Genetics. PMID 31492806 DOI: 10.1534/Genetics.119.302419  0.843
2019 Richards AL, Muehlbauer AL, Alazizi A, Burns MB, Findley A, Messina F, Gould TJ, Cascardo C, Pique-Regi R, Blekhman R, Luca F. Gut Microbiota Has a Widespread and Modifiable Effect on Host Gene Regulation. Msystems. 4. PMID 31481602 DOI: 10.1128/mSystems.00323-18  0.815
2019 Saad MH, Rumschlag M, Guerra MH, Savonen CL, Jaster AM, Olson PD, Alazizi A, Luca F, Pique-Regi R, Schmidt CJ, Bannon MJ. Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers. Scientific Reports. 9: 1534. PMID 30733491 DOI: 10.1038/S41598-018-38209-8  0.66
2019 Pique-Regi R, Romero R, Tarca AL, Sendler ED, Xu Y, Garcia-Flores V, Leng Y, Luca F, Hassan SS, Gomez-Lopez N. Author response: Single cell transcriptional signatures of the human placenta in term and preterm parturition Elife. DOI: 10.7554/Elife.52004.Sa2  0.331
2018 Imami L, Stanton SCE, Zilioli S, Tobin ET, Farrell AK, Luca F, Slatcher RB. Self-Disclosure and Perceived Responsiveness Among Youth With Asthma: Links to Affect and Anti-Inflammatory Gene Expression. Personality & Social Psychology Bulletin. 146167218808497. PMID 30486748 DOI: 10.1177/0146167218808497  0.345
2018 Kalita CA, Brown CD, Freiman A, Isherwood J, Wen X, Pique-Regi R, Luca F. High throughput characterization of genetic effects on DNA:protein binding and gene transcription. Genome Research. PMID 30254052 DOI: 10.1101/Gr.237354.118  0.819
2018 Pai AA, Luca F. Environmental influences on RNA processing: Biochemical, molecular and genetic regulators of cellular response. Wiley Interdisciplinary Reviews. Rna. e1503. PMID 30216698 DOI: 10.1002/Wrna.1503  0.404
2018 Farrell AK, Slatcher RB, Tobin ET, Imami L, Wildman DE, Luca F, Zilioli S. Socioeconomic status, family negative emotional climate, and anti-inflammatory gene expression among youth with asthma. Psychoneuroendocrinology. 91: 62-67. PMID 29529520 DOI: 10.1016/J.Psyneuen.2018.02.011  0.311
2018 Lacher SE, Alazizi A, Wang X, Bell DA, Pique-Regi R, Luca F, Slattery M. A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimer's disease. Redox Biology. 14: 686-693. PMID 29179108 DOI: 10.1016/J.Redox.2017.10.018  0.688
2017 Stanton SCE, Zilioli S, Briskin JL, Imami L, Tobin ET, Wildman DE, Mair-Meijers H, Luca F, Kane HS, Slatcher RB. Mothers' Attachment is Linked to their Children's Anti-Inflammatory Gene Expression via Maternal Warmth. Social Psychological and Personality Science. 8: 796-805. PMID 30410663 DOI: 10.1177/1948550616687125  0.31
2017 Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R. Functional Genomics of Host-Microbiome Interactions in Humans. Trends in Genetics : Tig. PMID 29107345 DOI: 10.1016/J.Tig.2017.10.001  0.426
2017 Kalita CA, Moyerbrailean GA, Brown C, Wen X, Luca F, Pique-Regi R. QuASAR-MPRA: Accurate allele-specific analysis for massively parallel reporter assays. Bioinformatics (Oxford, England). PMID 29028988 DOI: 10.1093/Bioinformatics/Btx598  0.796
2017 Richards AL, Watza D, Findley A, Alazizi A, Wen X, Pai AA, Pique-Regi R, Luca F. Environmental perturbations lead to extensive directional shifts in RNA processing. Plos Genetics. 13: e1006995. PMID 29023442 DOI: 10.1371/Journal.Pgen.1006995  0.806
2017 Talreja J, Farshi P, Alazizi A, Luca F, Pique-Regi R, Samavati L. RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes. Scientific Reports. 7: 2720. PMID 28577019 DOI: 10.1038/S41598-017-02941-4  0.712
2017 Wen X, Pique-Regi R, Luca F. Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization. Plos Genetics. 13: e1006646. PMID 28278150 DOI: 10.1371/Journal.Pgen.1006646  0.681
2016 Moyerbrailean GA, Richards AL, Kurtz D, Kalita CA, Davis GO, Harvey CT, Alazizi A, Watza D, Sorokin Y, Hauff N, Zhou X, Wen X, Pique-Regi R, Luca F. High-throughput allele-specific expression across 250 environmental conditions. Genome Research. 26: 1627-1638. PMID 27934696 DOI: 10.1101/Gr.209759.116  0.797
2016 Nédélec Y, Sanz J, Baharian G, Szpiech ZA, Pacis A, Dumaine A, Grenier JC, Freiman A, Sams AJ, Hebert S, Pagé Sabourin A, Luca F, Blekhman R, Hernandez RD, Pique-Regi R, et al. Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens. Cell. 167: 657-669.e21. PMID 27768889 DOI: 10.1016/J.Cell.2016.09.025  0.715
2016 Richards AL, Burns MB, Alazizi A, Barreiro LB, Pique-Regi R, Blekhman R, Luca F. Genetic and transcriptional analysis of human host response to healthy gut microbiota. Msystems. 1. PMID 27709125 DOI: 10.1128/mSystems.00067-16  0.813
2016 Wen X, Lee Y, Luca F, Pique-Regi R. Efficient Integrative Multi-SNP Association Analysis via Deterministic Approximation of Posteriors. American Journal of Human Genetics. PMID 27236919 DOI: 10.1016/J.Ajhg.2016.03.029  0.688
2016 Moyerbrailean GA, Kalita CA, Harvey CT, Wen X, Luca F, Pique-Regi R. Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding? Plos Genetics. 12: e1005875. PMID 26901046 DOI: 10.1371/Journal.Pgen.1005875  0.779
2015 Moyerbrailean GA, Davis GO, Harvey CT, Watza D, Wen X, Pique-Regi R, Luca F. A high-throughput RNA-seq approach to profile transcriptional responses. Scientific Reports. 5: 14976. PMID 26510397 DOI: 10.1038/Srep14976  0.786
2015 Pacis A, Tailleux L, Morin AM, Lambourne J, Maclsaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, Hansen KD, Gicquel B, Yu M, Pai A, He C, et al. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Genome Research. PMID 26392366 DOI: 10.1101/Gr.192005.115  0.65
2015 Wen X, Luca F, Pique-Regi R. Cross-population joint analysis of eQTLs: fine mapping and functional annotation. Plos Genetics. 11: e1005176. PMID 25906321 DOI: 10.1371/Journal.Pgen.1005176  0.691
2015 Harvey CT, Moyerbrailean GA, Davis GO, Wen X, Luca F, Pique-Regi R. QuASAR: quantitative allele-specific analysis of reads. Bioinformatics (Oxford, England). 31: 1235-42. PMID 25480375 DOI: 10.1093/Bioinformatics/Btu802  0.82
2013 Luca F, Di Rienzo A. Allelic imbalance assays to quantify allele-specific gene expression and transcription factor binding. Methods in Molecular Biology (Clifton, N.J.). 1015: 201-11. PMID 23824858 DOI: 10.1007/978-1-62703-435-7_13  0.704
2013 Luca F, Maranville JC, Richards AL, Witonsky DB, Stephens M, Di Rienzo A. Genetic, functional and molecular features of glucocorticoid receptor binding. Plos One. 8: e61654. PMID 23637875 DOI: 10.1371/Journal.Pone.0061654  0.824
2013 Wall JD, Kim SK, Luca F, Carbone L, Mootnick AR, de Jong PJ, Di Rienzo A. Incomplete lineage sorting is common in extant gibbon genera. Plos One. 8: e53682. PMID 23341974 DOI: 10.1371/Journal.Pone.0053682  0.556
2012 Maranville JC, Luca F, Stephens M, Di Rienzo A. Mapping gene-environment interactions at regulatory polymorphisms: insights into mechanisms of phenotypic variation. Transcription. 3: 56-62. PMID 22414753 DOI: 10.4161/trns.19497  0.831
2011 Maranville JC, Luca F, Richards AL, Wen X, Witonsky DB, Baxter S, Stephens M, Di Rienzo A. Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes. Plos Genetics. 7: e1002162. PMID 21750684 DOI: 10.1371/Journal.Pgen.1002162  0.825
2011 Luca F, Hudson RR, Witonsky DB, Di Rienzo A. A reduced representation approach to population genetic analyses and applications to human evolution. Genome Research. 21: 1087-98. PMID 21628451 DOI: 10.1101/Gr.119792.110  0.598
2010 Luca F, Perry GH, Di Rienzo A. Evolutionary adaptations to dietary changes. Annual Review of Nutrition. 30: 291-314. PMID 20420525 DOI: 10.1146/Annurev-Nutr-080508-141048  0.594
2009 Luca F, Kashyap S, Southard C, Zou M, Witonsky D, Di Rienzo A, Conzen SD. Adaptive variation regulates the expression of the human SGK1 gene in response to stress. Plos Genetics. 5: e1000489. PMID 19461886 DOI: 10.1371/Journal.Pgen.1000489  0.719
2008 Luca F, Bubba G, Basile M, Brdicka R, Michalodimitrakis E, Rickards O, Vershubsky G, Quintana-Murci L, Kozlov AI, Novelletto A. Multiple advantageous amino acid variants in the NAT2 gene in human populations. Plos One. 3: e3136. PMID 18773084 DOI: 10.1371/Journal.Pone.0003136  0.392
2008 Coop G, Bullaughey K, Luca F, Przeworski M. The timing of selection at the human FOXP2 gene. Molecular Biology and Evolution. 25: 1257-9. PMID 18413354 DOI: 10.1093/Molbev/Msn091  0.395
2008 Quintana-Murci L, Quach H, Harmant C, Luca F, Massonnet B, Patin E, Sica L, Mouguiama-Daouda P, Comas D, Tzur S, Balanovsky O, Kidd KK, Kidd JR, van der Veen L, Hombert JM, et al. Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers. Proceedings of the National Academy of Sciences of the United States of America. 105: 1596-601. PMID 18216239 DOI: 10.1073/Pnas.0711467105  0.339
2006 Patin E, Barreiro LB, Sabeti PC, Austerlitz F, Luca F, Sajantila A, Behar DM, Semino O, Sakuntabhai A, Guiso N, Gicquel B, McElreavey K, Harding RM, Heyer E, Quintana-Murci L. Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes. American Journal of Human Genetics. 78: 423-36. PMID 16416399 DOI: 10.1086/500614  0.464
2005 Luca F, Basile M, Giacomo FD, Novelletto A. Independent methods for evolutionary genetic dating provide insights into Y-chromosomal STR mutation rates confirming data from direct father-son transmissions. Human Genetics. 118: 153-65. PMID 16136324 DOI: 10.1007/S00439-005-0028-6  0.34
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