Year |
Citation |
Score |
2021 |
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, ... ... Singh H, et al. Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung. Cell Reports. Medicine. 100476. PMID 34873589 DOI: 10.1016/j.xcrm.2021.100476 |
0.616 |
|
2021 |
Ma X, Somasundaram A, Qi Z, Hartman DJ, Singh H, Osmanbeyoglu HU. SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators. Nucleic Acids Research. PMID 34500467 DOI: 10.1093/nar/gkab745 |
0.32 |
|
2021 |
Louis K, Bailly E, Macedo C, Lau L, Ramaswami B, Chang A, Chandran U, Landsittel D, Gu X, Chalasani G, Zeevi A, Randhawa P, Singh H, Lefaucheur C, Metes D. T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants. Jci Insight. PMID 34032636 DOI: 10.1172/jci.insight.148881 |
0.301 |
|
2021 |
Chen D, Wang Y, Manakkat Vijay GK, Fu S, Nash CW, Xu D, He D, Salomonis N, Singh H, Xu H. Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation. Nature Immunology. PMID 34031613 DOI: 10.1038/s41590-021-00936-y |
0.346 |
|
2021 |
Reiman D, Manakkat Vijay GK, Xu H, Sonin A, Chen D, Salomonis N, Singh H, Khan AA. Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination. Plos Computational Biology. 17: e1008094. PMID 33939691 DOI: 10.1371/journal.pcbi.1008094 |
0.317 |
|
2021 |
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, ... ... Singh H, et al. Bifurcated monocyte states are predictive of mortality in severe COVID-19. Biorxiv : the Preprint Server For Biology. PMID 33594364 DOI: 10.1101/2021.02.10.430499 |
0.613 |
|
2020 |
Almanan M, Raynor J, Ogunsulire I, Malyshkina A, Mukherjee S, Hummel SA, Ingram JT, Saini A, Xie MM, Alenghat T, Way SS, Deepe GS, Divanovic S, Singh H, Miraldi E, et al. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science Advances. 6: eabb0806. PMID 32832688 DOI: 10.1126/Sciadv.Abb0806 |
0.3 |
|
2020 |
Antoniou K, Ender F, Vollbrandt T, Laumonnier Y, Rathmann F, Pasare C, Singh H, Köhl J. Allergen-Induced C5a/C5aR1 Axis Activation in Pulmonary CD11b cDCs Promotes Pulmonary Tolerance through Downregulation of CD40. Cells. 9. PMID 31991941 DOI: 10.3390/Cells9020300 |
0.321 |
|
2019 |
Chaudhri VK, Dienger-Stambaugh K, Wu Z, Shrestha M, Singh H. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Nature Immunology. PMID 31873292 DOI: 10.1038/s41590-019-0565-0 |
0.362 |
|
2018 |
Rydyznski CE, Cranert SA, Zhou JQ, Xu H, Kleinstein SH, Singh H, Waggoner SN. Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal Centers. Cell Reports. 24: 3367-3373.e4. PMID 30257198 DOI: 10.1016/J.Celrep.2018.08.075 |
0.359 |
|
2018 |
Karki S, Kennedy DE, Mclean K, Grzybowski AT, Maienschein-Cline M, Banerjee S, Xu H, Davis E, Mandal M, Labno C, Powers SE, Le Beau MM, Dinner AR, Singh H, Ruthenburg AJ, et al. Regulated Capture of Vκ Gene Topologically Associating Domains by Transcription Factories. Cell Reports. 24: 2443-2456. PMID 30157436 DOI: 10.1016/J.Celrep.2018.07.091 |
0.364 |
|
2018 |
Rochman Y, Dienger-Stambaugh K, Richgels PK, Lewkowich IP, Kartashov AV, Barski A, Khurana Hershey GK, Leonard WJ, Singh H. TSLP signaling in CD4T cells programs a pathogenic T helper 2 cell state. Science Signaling. 11. PMID 29535264 DOI: 10.1126/Scisignal.Aam8858 |
0.353 |
|
2018 |
Patterson AR, Endale M, Lampe K, Aksoylar HI, Flagg A, Woodgett JR, Hildeman D, Jordan MB, Singh H, Kucuk Z, Bleesing J, Hoebe K. Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology. Nature Communications. 9: 430. PMID 29382851 DOI: 10.1038/S41467-018-02897-7 |
0.356 |
|
2017 |
Franchi L, Monteleone I, Hao LY, Spahr MA, Zhao W, Liu X, Demock K, Kulkarni A, Lesch CA, Sanchez B, Carter L, Marafini I, Hu X, Mashadova O, Yuan M, ... ... Singh H, et al. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28242647 DOI: 10.4049/Jimmunol.1600810 |
0.316 |
|
2017 |
Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. The Journal of Cell Biology. PMID 28130292 DOI: 10.1083/Jcb.201512012 |
0.421 |
|
2016 |
Olsson A, Venkatasubramanian M, Chaudhri VK, Aronow BJ, Salomonis N, Singh H, Grimes HL. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature. PMID 27580035 DOI: 10.1038/Nature19348 |
0.459 |
|
2016 |
Olsson A, Venkatasubramanian M, Chaudhri VK, Aronow BJ, Salomonis N, Singh H, Grimes HL. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.010 |
0.358 |
|
2015 |
Xu H, Chaudhri VK, Wu Z, Biliouris K, Dienger-Stambaugh K, Rochman Y, Singh H. Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8. Nature Immunology. PMID 26437243 DOI: 10.1038/Ni.3287 |
0.5 |
|
2015 |
Olsson A, Salomonis N, Singh H, Grimes HL. Identification of the Origin of Eosinophils Blood. 126: 886-886. DOI: 10.1182/Blood.V126.23.886.886 |
0.379 |
|
2014 |
Singh H. Transcriptional and epigenetic networks orchestrating immune cell development and function. Immunological Reviews. 261: 5-8. PMID 25123273 DOI: 10.1111/Imr.12210 |
0.368 |
|
2014 |
Singh H, Khan AA, Dinner AR. Gene regulatory networks in the immune system. Trends in Immunology. 35: 211-8. PMID 24768519 DOI: 10.1016/J.It.2014.03.006 |
0.357 |
|
2014 |
Clark MR, Mandal M, Ochiai K, Singh H. Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling. Nature Reviews. Immunology. 14: 69-80. PMID 24378843 DOI: 10.1038/Nri3570 |
0.424 |
|
2014 |
Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nature Immunology. 15: 161-7. PMID 24362890 DOI: 10.1038/Ni.2795 |
0.357 |
|
2014 |
Olsson A, Grimes HL, Chaudhri VK, Dexheimer P, Aronow BJ, Singh H. Single Cell Transcriptome-Based Dissection of Lineage Fate Decisions in Myelopoiesis Blood. 124: 1395-1395. DOI: 10.1182/Blood.V124.21.1395.1395 |
0.46 |
|
2014 |
Grimes HL, Olsson A, Aronow B, Chaudhri V, Dexheimer P, Singh H. Single cell transcriptome-based dissection of lineage fate decisions in myelopoiesis Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.073 |
0.459 |
|
2013 |
Singh H, Glasmacher E, Chang AB, Vander Lugt B. The molecular choreography of IRF4 and IRF8 with immune system partners. Cold Spring Harbor Symposia On Quantitative Biology. 78: 101-4. PMID 24752218 DOI: 10.1101/Sqb.2013.78.020305 |
0.428 |
|
2013 |
Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nature Communications. 4: 2990. PMID 24356538 DOI: 10.1038/Ncomms3990 |
0.327 |
|
2013 |
Spooner CJ, Lesch J, Yan D, Khan AA, Abbas A, Ramirez-Carrozzi V, Zhou M, Soriano R, Eastham-Anderson J, Diehl L, Lee WP, Modrusan Z, Pappu R, Xu M, DeVoss J, ... Singh H, et al. Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nature Immunology. 14: 1229-36. PMID 24141388 DOI: 10.1038/Ni.2743 |
0.407 |
|
2013 |
Ochiai K, Maienschein-Cline M, Simonetti G, Chen J, Rosenthal R, Brink R, Chong AS, Klein U, Dinner AR, Singh H, Sciammas R. Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity. 38: 918-29. PMID 23684984 DOI: 10.1016/J.Immuni.2013.04.009 |
0.487 |
|
2012 |
Tussiwand R, Lee WL, Murphy TL, Mashayekhi M, KC W, Albring JC, Satpathy AT, Rotondo JA, Edelson BT, Kretzer NM, Wu X, Weiss LA, Glasmacher E, Li P, Liao W, ... ... Singh H, et al. Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature. 490: 502-7. PMID 22992524 DOI: 10.1038/Nature11531 |
0.415 |
|
2012 |
Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, ... ... Singh H, et al. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (New York, N.Y.). 338: 975-80. PMID 22983707 DOI: 10.1126/Science.1228309 |
0.451 |
|
2012 |
Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H. DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell. 149: 1474-87. PMID 22726435 DOI: 10.1016/J.Cell.2012.04.035 |
0.377 |
|
2012 |
Seiler MP, Mathew R, Liszewski MK, Spooner CJ, Spooner C, Barr K, Meng F, Singh H, Bendelac A. Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nature Immunology. 13: 264-71. PMID 22306690 DOI: 10.1038/Ni.2230 |
0.433 |
|
2012 |
Ochiai K, Maienschein-Cline M, Mandal M, Triggs JR, Bertolino E, Sciammas R, Dinner AR, Clark MR, Singh H. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nature Immunology. 13: 300-7. PMID 22267219 DOI: 10.1038/Ni.2210 |
0.401 |
|
2012 |
Becker AM, Michael DG, Satpathy AT, Sciammas R, Singh H, Bhattacharya D. IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood. 119: 2003-12. PMID 22238324 DOI: 10.1182/Blood-2011-06-364976 |
0.374 |
|
2011 |
Demarco IA, Singh H. The A-MYSM power of deubiquitinases. Immunity. 35: 847-9. PMID 22195739 DOI: 10.1016/J.Immuni.2011.12.009 |
0.332 |
|
2011 |
Rutz S, Noubade R, Eidenschenk C, Ota N, Zeng W, Zheng Y, Hackney J, Ding J, Singh H, Ouyang W. Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells. Nature Immunology. 12: 1238-45. PMID 22001828 DOI: 10.1038/Ni.2134 |
0.327 |
|
2011 |
Sciammas R, Li Y, Warmflash A, Song Y, Dinner AR, Singh H. An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Molecular Systems Biology. 7: 495. PMID 21613984 DOI: 10.1038/Msb.2011.25 |
0.467 |
|
2010 |
Mewborn SK, Puckelwartz MJ, Abuisneineh F, Fahrenbach JP, Zhang Y, MacLeod H, Dellefave L, Pytel P, Selig S, Labno CM, Reddy K, Singh H, McNally E. Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation. Plos One. 5: e14342. PMID 21179469 DOI: 10.1371/Journal.Pone.0014342 |
0.321 |
|
2010 |
Singh H, Demarco IA. Immunology. Double TIP-ping. Science (New York, N.Y.). 329: 914-5. PMID 20724627 DOI: 10.1126/Science.1194316 |
0.397 |
|
2010 |
Jo SH, Schatz JH, Acquaviva J, Singh H, Ren R. Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis. Blood. 116: 2759-67. PMID 20585039 DOI: 10.1182/Blood-2009-07-234559 |
0.385 |
|
2010 |
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Molecular Cell. 38: 576-89. PMID 20513432 DOI: 10.1016/J.Molcel.2010.05.004 |
0.482 |
|
2010 |
Hu Z, Negrotto S, Gu X, Mahfouz R, Ng KP, Ebrahem Q, Copelan E, Singh H, Maciejewski JP, Saunthararajah Y. Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Molecular Cancer Therapeutics. 9: 1536-43. PMID 20501800 DOI: 10.1158/1535-7163.Mct-10-0191 |
0.388 |
|
2010 |
Aikawa Y, Katsumoto T, Zhang P, Shima H, Shino M, Terui K, Ito E, Ohno H, Stanley ER, Singh H, Tenen DG, Kitabayashi I. PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nature Medicine. 16: 580-5, 1p following . PMID 20418886 DOI: 10.1038/Nm.2122 |
0.401 |
|
2010 |
Singh H. CS1-1 IL-7 signaling and the control of B cell development Cytokine. 52: 5. DOI: 10.1016/J.Cyto.2010.07.024 |
0.328 |
|
2009 |
Spooner CJ, Cheng JX, Pujadas E, Laslo P, Singh H. A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity. 31: 576-86. PMID 19818654 DOI: 10.1016/J.Immuni.2009.07.011 |
0.504 |
|
2009 |
Mandal M, Powers SE, Ochiai K, Georgopoulos K, Kee BL, Singh H, Clark MR. Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nature Immunology. 10: 1110-7. PMID 19734904 DOI: 10.1038/Ni.1785 |
0.439 |
|
2009 |
Johnson K, Reddy KL, Singh H. Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development. Advances in Experimental Medicine and Biology. 650: 133-47. PMID 19731807 DOI: 10.1007/978-1-4419-0296-2_11 |
0.472 |
|
2009 |
Singh H. Teeing up transcription on CpG islands. Cell. 138: 14-6. PMID 19596228 DOI: 10.1016/J.Cell.2009.06.028 |
0.352 |
|
2008 |
Laslo P, Pongubala JM, Lancki DW, Singh H. Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Seminars in Immunology. 20: 228-35. PMID 18771937 DOI: 10.1016/J.Smim.2008.08.003 |
0.423 |
|
2008 |
Singh H. PU.1, a shared transcriptional regulator of innate and adaptive immune cell fates. Journal of Immunology (Baltimore, Md. : 1950). 181: 1595-6. PMID 18641293 DOI: 10.4049/Jimmunol.181.3.1595 |
0.449 |
|
2008 |
Reddy KL, Singh H. Using molecular tethering to analyze the role of nuclear compartmentalization in the regulation of mammalian gene activity. Methods (San Diego, Calif.). 45: 242-51. PMID 18602999 DOI: 10.1016/J.Ymeth.2008.06.013 |
0.363 |
|
2008 |
Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nature Immunology. 9: 927-36. PMID 18568028 DOI: 10.1038/Ni.1626 |
0.671 |
|
2008 |
Johnson K, Hashimshony T, Sawai CM, Pongubala JM, Skok JA, Aifantis I, Singh H. Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity. 28: 335-45. PMID 18280186 DOI: 10.1016/J.Immuni.2007.12.019 |
0.454 |
|
2008 |
Reddy KL, Zullo JM, Bertolino E, Singh H. Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature. 452: 243-7. PMID 18272965 DOI: 10.1038/Nature06727 |
0.413 |
|
2008 |
Pongubala JM, Northrup DL, Lancki DW, Medina KL, Treiber T, Bertolino E, Thomas M, Grosschedl R, Allman D, Singh H. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nature Immunology. 9: 203-15. PMID 18176567 DOI: 10.1038/Ni1555 |
0.699 |
|
2008 |
Cheng JX, Laslo P, Spooner C, Bertolino E, Singh H. Molecular Mechanisms Underlying the Regulation of Alternate Macrophage and Neutrophil Gene Programs by the Egr Transcription Factors Blood. 112: 4773-4773. DOI: 10.1182/Blood.V112.11.4773.4773 |
0.433 |
|
2007 |
Gantner BN, Singh H. Immunology: Short-term memory. Nature. 447: 916-7. PMID 17581569 DOI: 10.1038/447916A |
0.333 |
|
2007 |
Littman DR, Singh H. Immunology. Asymmetry and immune memory. Science (New York, N.Y.). 315: 1673-4. PMID 17379796 DOI: 10.1126/Science.1141184 |
0.311 |
|
2007 |
Singh H, Pongubala JM, Medina KL. Gene regulatory networks that orchestrate the development of B lymphocyte precursors. Advances in Experimental Medicine and Biology. 596: 57-62. PMID 17338175 DOI: 10.1007/0-387-46530-8_5 |
0.423 |
|
2007 |
Singh H. Shaping a helper T cell identity Nature Immunology. 8: 119-120. PMID 17242680 DOI: 10.1038/Ni0207-119 |
0.394 |
|
2007 |
Krysinska H, Hoogenkamp M, Ingram R, Wilson N, Tagoh H, Laslo P, Singh H, Bonifer C. A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Molecular and Cellular Biology. 27: 878-87. PMID 17116688 DOI: 10.1128/Mcb.01915-06 |
0.459 |
|
2006 |
Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 126: 755-66. PMID 16923394 DOI: 10.1016/J.Cell.2006.06.052 |
0.443 |
|
2006 |
Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, Singh H. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity. 25: 225-36. PMID 16919487 DOI: 10.1016/J.Immuni.2006.07.009 |
0.592 |
|
2006 |
Singh H, Sciammas R. Shedding B cell identity. Immunity. 24: 239-40. PMID 16546090 DOI: 10.1016/J.Immuni.2006.03.005 |
0.415 |
|
2006 |
Singh H, Pongubala JM. Gene regulatory networks and the determination of lymphoid cell fates. Current Opinion in Immunology. 18: 116-20. PMID 16473505 DOI: 10.1016/J.Coi.2006.01.014 |
0.439 |
|
2006 |
Acquaviva J, Schatz J, Singh H, Ren R. IRF-4 Functions as a Myeloid Tumor Suppressor. Blood. 108: 2206-2206. DOI: 10.1182/Blood.V108.11.2206.2206 |
0.423 |
|
2005 |
Medina KL, Singh H. Gene regulatory networks orchestrating B cell fate specification, commitment, and differentiation. Current Topics in Microbiology and Immunology. 290: 1-14. PMID 16480036 DOI: 10.1007/3-540-26363-2_1 |
0.475 |
|
2005 |
Bertolino E, Reddy K, Medina KL, Parganas E, Ihle J, Singh H. Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nature Immunology. 6: 836-43. PMID 16025120 DOI: 10.1038/Ni1226 |
0.423 |
|
2005 |
Medina KL, Singh H. Genetic networks that regulate B lymphopoiesis. Current Opinion in Hematology. 12: 203-9. PMID 15867576 DOI: 10.1097/01.Moh.0000160735.67596.A0 |
0.47 |
|
2005 |
Singh H, Medina KL, Pongubala JM. Contingent gene regulatory networks and B cell fate specification. Proceedings of the National Academy of Sciences of the United States of America. 102: 4949-53. PMID 15788530 DOI: 10.1073/Pnas.0500480102 |
0.461 |
|
2005 |
Tamura T, Tailor P, Yamaoka K, Kong HJ, Tsujimura H, O'Shea JJ, Singh H, Ozato K. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. Journal of Immunology (Baltimore, Md. : 1950). 174: 2573-81. PMID 15728463 DOI: 10.4049/Jimmunol.174.5.2573 |
0.342 |
|
2004 |
Medina KL, Pongubala JM, Reddy KL, Lancki DW, Dekoter R, Kieslinger M, Grosschedl R, Singh H. Assembling a gene regulatory network for specification of the B cell fate. Developmental Cell. 7: 607-17. PMID 15469848 DOI: 10.1016/J.Devcel.2004.08.006 |
0.681 |
|
2004 |
Maier H, Ostraat R, Gao H, Fields S, Shinton SA, Medina KL, Ikawa T, Murre C, Singh H, Hardy RR, Hagman J. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nature Immunology. 5: 1069-77. PMID 15361869 DOI: 10.1038/Ni1119 |
0.484 |
|
2004 |
Schatz J, Ren R, Singh H. Loss of IRF-4 Exacerbates the CML-Like Phenotype of IRF-8 Knockout Mice. Blood. 104: 2952-2952. DOI: 10.1182/Blood.V104.11.2952.2952 |
0.382 |
|
2003 |
Dahl R, Walsh JC, Lancki D, Laslo P, Iyer SR, Singh H, Simon MC. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nature Immunology. 4: 1029-36. PMID 12958595 DOI: 10.1038/Ni973 |
0.448 |
|
2003 |
Lu R, Medina KL, Lancki DW, Singh H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes & Development. 17: 1703-8. PMID 12832394 DOI: 10.1101/Gad.1104803 |
0.474 |
|
2002 |
Escalante CR, Brass AL, Pongubala JM, Shatova E, Shen L, Singh H, Aggarwal AK. Crystal structure of PU.1/IRF-4/DNA ternary complex. Molecular Cell. 10: 1097-105. PMID 12453417 DOI: 10.1016/S1097-2765(02)00703-7 |
0.387 |
|
2002 |
Walsh JC, DeKoter RP, Lee HJ, Smith ED, Lancki DW, Gurish MF, Friend DS, Stevens RL, Anastasi J, Singh H. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity. 17: 665-76. PMID 12433372 DOI: 10.1016/S1074-7613(02)00452-1 |
0.476 |
|
2002 |
Escalante CR, Shen L, Escalante MC, Brass AL, Edwards TA, Singh H, Aggarwal AK. Crystallization and characterization of PU.1/IRF-4/DNA ternary complex. Journal of Structural Biology. 139: 55-9. PMID 12372320 DOI: 10.1016/S1047-8477(02)00514-2 |
0.348 |
|
2002 |
Bertolino E, Singh H. POU/TBP Cooperativity: A Mechanism for Enhancer Action from a Distance Molecular Cell. 10: 397-407. PMID 12191484 DOI: 10.1016/S1097-2765(02)00597-X |
0.366 |
|
2002 |
Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. The Journal of Experimental Medicine. 195: 1003-12. PMID 11956291 DOI: 10.1084/Jem.20011128 |
0.4 |
|
2002 |
Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, Singh H. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science (New York, N.Y.). 296: 158-62. PMID 11935030 DOI: 10.1126/Science.1068768 |
0.433 |
|
2002 |
DeKoter RP, Lee HJ, Singh H. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity. 16: 297-309. PMID 11869689 DOI: 10.1016/S1074-7613(02)00269-8 |
0.437 |
|
2002 |
Singh H. Introduction: regulation of lymphocyte development Seminars in Immunology. 14: 359-360. DOI: 10.1016/S1044532302000696 |
0.327 |
|
2001 |
Singh H. Detection, purification, and characterization of cDNA clones encoding DNA-binding proteins Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. PMID 18265090 DOI: 10.1002/0471142727.Mb1207S13 |
0.363 |
|
2001 |
Colucci F, Samson SI, DeKoter RP, Lantz O, Singh H, Di Santo JP. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood. 97: 2625-32. PMID 11313251 DOI: 10.1182/Blood.V97.9.2625 |
0.433 |
|
2001 |
Singh H, DeKoter RP, Walsh JC. PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates. Cold Spring Harbor Symposia On Quantitative Biology. 64: 13-20. PMID 11232277 DOI: 10.1101/Sqb.1999.64.13 |
0.443 |
|
2000 |
DeKoter RP, Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science (New York, N.Y.). 288: 1439-41. PMID 10827957 DOI: 10.1126/Science.288.5470.1439 |
0.491 |
|
1999 |
Brass AL, Zhu AQ, Singh H. Assembly requirements of PU.1–Pip (IRF‐4) activator complexes: inhibiting function in vivo using fused dimers The Embo Journal. 18: 977-991. PMID 10022840 DOI: 10.1093/Emboj/18.4.977 |
0.471 |
|
1999 |
Glimcher LH, Singh H. Transcription factors in lymphocyte development - T and B cells get together Cell. 96: 13-23. PMID 9989493 DOI: 10.1016/S0092-8674(00)80955-1 |
0.387 |
|
1998 |
DeKoter RP, Walsh JC, Singh H. PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. The Embo Journal. 17: 4456-68. PMID 9687512 DOI: 10.1093/Emboj/17.15.4456 |
0.383 |
|
1997 |
Shah PC, Bertolino E, Singh H. Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription. The Embo Journal. 16: 7105-7117. PMID 9384588 DOI: 10.1093/Emboj/16.23.7105 |
0.485 |
|
1997 |
Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity. 6: 437-47. PMID 9133423 DOI: 10.1016/S1074-7613(00)80287-3 |
0.455 |
|
1996 |
Brass AL, Kehrli E, Eisenbeis CF, Storb U, Singh H. Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. Genes & Development. 10: 2335-47. PMID 8824592 DOI: 10.1101/Gad.10.18.2335 |
0.453 |
|
1996 |
Singh H. Gene targeting reveals a hierarchy of transcription factors regulating specification of lymphoid cell fates Current Opinion in Immunology. 8: 160-165. PMID 8725938 DOI: 10.1016/S0952-7915(96)80053-7 |
0.489 |
|
1996 |
Simon MC, Olson M, Scott E, Hack A, Su G, Singh H. Terminal myeloid gene expression and differentiation requires the transcription factor PU.1. Current Topics in Microbiology and Immunology. 211: 113-9. PMID 8585941 DOI: 10.1007/978-3-642-85232-9_11 |
0.362 |
|
1995 |
Olson MC, Scott EW, Hack AA, Su GH, Tenen DG, Singh H, Simon MC. PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity. 3: 703-14. PMID 8777716 DOI: 10.1016/1074-7613(95)90060-8 |
0.441 |
|
1995 |
Eisenbeis CF, Singh H, Storb U. Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. Genes & Development. 9: 1377-87. PMID 7797077 DOI: 10.1101/Gad.9.11.1377 |
0.461 |
|
1994 |
Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages Science. 265: 1573-1577. PMID 8079170 DOI: 10.1126/Science.8079170 |
0.373 |
|
1994 |
Klug CA, Gerety SJ, Shah PC, Chen YY, Rice NR, Rosenberg N, Singh H. The v-abl tyrosine kinase negatively regulates NF-κB/Rel factors and blocks κ gene transcription in pre-B lymphocytes Genes and Development. 8: 678-687. PMID 7926758 DOI: 10.1101/Gad.8.6.678 |
0.666 |
|
1994 |
Singh H. Genetic analysis of transcription factors implicated in B lymphocyte development Immunologic Research. 13: 280-290. PMID 7616055 DOI: 10.1007/Bf02935619 |
0.503 |
|
1993 |
Singh H. Specific recognition site probes for isolating genes encoding DNA-binding proteins Methods in Enzymology. 218: 551-567. PMID 8510547 DOI: 10.1016/0076-6879(93)18041-A |
0.379 |
|
1993 |
Eisenbeis CF, Singh H, Storb U. PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer. Molecular and Cellular Biology. 13: 6452-61. PMID 8413244 DOI: 10.1128/Mcb.13.10.6452 |
0.444 |
|
1993 |
Feldhaus AL, Klug CA, Arvin KL, Singh H. Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation Embo Journal. 12: 2763-2772. PMID 8334992 DOI: 10.1002/J.1460-2075.1993.Tb05937.X |
0.706 |
|
1993 |
Andersen B, Schonemann MD, Flynn SE, Pearse RV, Singh H, Rosenfeld MG. Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis. Science (New York, N.Y.). 260: 78-82. PMID 7682011 DOI: 10.1126/Science.7682011 |
0.381 |
|
1992 |
Feldhaus AL, Mbangkollo D, Arvin KL, Klug CA, Singh H. BLyF, a Novel Cell-Type- and Stage-Specific Regulator of the B-Lymphocyte Gene mb-1 Molecular and Cellular Biology. 12: 1126-1133. PMID 1545794 DOI: 10.1128/mcb.12.3.1126-1133.1992 |
0.708 |
|
1991 |
Miller CL, Feldhaus AL, Rooney JW, Rhodes LD, Sibley CH, Singh H. Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation. Molecular and Cellular Biology. 11: 4885-94. PMID 1922024 DOI: 10.1128/Mcb.11.10.4885 |
0.5 |
|
1991 |
Zhang Y, Babin J, Feldhaus AL, Singh H, Sharp PA, Bina M. HTF4: a new human helix-loop-helix protein. Nucleic Acids Research. 19: 4555. PMID 1886779 DOI: 10.1093/Nar/19.16.4555 |
0.416 |
|
1990 |
Baldwin AS, LeClair KP, Singh H, Sharp PA. A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes. Molecular and Cellular Biology. 10: 1406-14. PMID 2108316 DOI: 10.1128/mcb.10.4.1406-1414.1990 |
0.571 |
|
1990 |
Singh H. Molecular cloning of genes encoding transcription factors with the use of recognition site probes Genetic Engineering. 12: 317-330. PMID 1366707 DOI: 10.1007/978-1-4613-0641-2_16 |
0.442 |
|
1988 |
Staudt LM, Clerc RG, Singh H, LeBowitz JH, Sharp PA, Baltimore D. Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif Science. 241: 577-580. PMID 3399892 DOI: 10.1126/Science.3399892 |
0.72 |
|
1988 |
Singh H, LeBowitz JH, Baldwin AS, Sharp PA. Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell. 52: 415-23. PMID 2964277 DOI: 10.1016/S0092-8674(88)80034-5 |
0.586 |
|
1986 |
Staudt LM, Singh H, Sen R, Wirth T, Sharp PA, Baltimore D. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature. 323: 640-3. PMID 3095662 DOI: 10.1038/323640A0 |
0.658 |
|
1986 |
Singh H, Sen R, Baltimore D, Sharp PA. A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature. 319: 154-8. PMID 3079885 DOI: 10.1038/319154A0 |
0.6 |
|
1986 |
Singh H, Brooke RG, Pausch MH, Williams GT, Trainor C, Dumas LB. Yeast DNA primase and DNA polymerase activities. An analysis of RNA priming and its coupling to DNA synthesis. The Journal of Biological Chemistry. 261: 8564-9. PMID 2424899 |
0.666 |
|
1984 |
Singh H, Dumas LB. A DNA primase that copurifies with the major DNA polymerase from the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 259: 7936-40. PMID 6376495 |
0.668 |
|
1982 |
Singh H, Bieker JJ, Dumas LB. Genetic transformation of Saccharomyces cerevisiae with single-stranded circular DNA vectors. Gene. 20: 441-9. PMID 6299901 DOI: 10.1016/0378-1119(82)90213-X |
0.652 |
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