| Year |
Citation |
Score |
| 2023 |
Boeynaems S, Dorone Y, Zhuang Y, Shabardina V, Huang G, Marian A, Kim G, Sanyal A, Şen NE, Griffith D, Docampo R, Lasker K, Ruiz-Trillo I, Auburger G, Holehouse AS, et al. Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates. Molecular Cell. PMID 37295429 DOI: 10.1016/j.molcel.2023.05.025 |
0.711 |
|
| 2023 |
Boeynaems S, Ma XR, Yeong V, Ginell GM, Chen JH, Blum JA, Nakayama L, Sanyal A, Briner A, Van Haver D, Pauwels J, Ekman A, Schmidt HB, Sundararajan K, Porta L, et al. Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease. Biorxiv : the Preprint Server For Biology. PMID 36945394 DOI: 10.1101/2023.03.09.531820 |
0.709 |
|
| 2022 |
Kim G, Nakayama L, Blum JA, Akiyama T, Boeynaems S, Chakraborty M, Couthouis J, Tassoni-Tsuchida E, Rodriguez CM, Bassik MC, Gitler AD. Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2. Cell Reports. 41: 111508. PMID 36288714 DOI: 10.1016/j.celrep.2022.111508 |
0.642 |
|
| 2022 |
Lasker K, Boeynaems S, Lam V, Scholl D, Stainton E, Briner A, Jacquemyn M, Daelemans D, Deniz A, Villa E, Holehouse AS, Gitler AD, Shapiro L. The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Nature Communications. 13: 5643. PMID 36163138 DOI: 10.1038/s41467-022-33221-z |
0.517 |
|
| 2022 |
Boeynaems S, Gitler AD. You come at the misfolded proteins, you best not miss. Trends in Biochemical Sciences. 47: 1-2. PMID 34654581 DOI: 10.1016/j.tibs.2021.10.001 |
0.565 |
|
| 2021 |
Dorone Y, Boeynaems S, Flores E, Jin B, Hateley S, Bossi F, Lazarus E, Pennington JG, Michiels E, De Decker M, Vints K, Baatsen P, Bassel GW, Otegui MS, Holehouse AS, et al. A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation. Cell. PMID 34233164 DOI: 10.1016/j.cell.2021.06.009 |
0.518 |
|
| 2021 |
Friedman AK, Boeynaems S, Baker LA. Synthetic hydrogel mimics of the nuclear pore complex for the study of nucleocytoplasmic transport defects in C9orf72 ALS/FTD. Analytical and Bioanalytical Chemistry. PMID 34170347 DOI: 10.1007/s00216-021-03478-2 |
0.309 |
|
| 2021 |
Fumagalli L, Young FL, Boeynaems S, De Decker M, Mehta AR, Swijsen A, Fazal R, Guo W, Moisse M, Beckers J, Dedeene L, Selvaraj BT, Vandoorne T, Madan V, van Blitterswijk M, et al. -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science Advances. 7. PMID 33837088 DOI: 10.1126/sciadv.abg3013 |
0.586 |
|
| 2021 |
Fazal R, Boeynaems S, Swijsen A, De Decker M, Fumagalli L, Moisse M, Vanneste J, Guo W, Boon R, Vercruysse T, Eggermont K, Swinnen B, Beckers J, Pakravan D, Vandoorne T, et al. HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The Embo Journal. e106177. PMID 33694180 DOI: 10.15252/embj.2020106177 |
0.34 |
|
| 2019 |
Gittings LM, Boeynaems S, Lightwood D, Clargo A, Topia S, Nakayama L, Troakes C, Mann DMA, Gitler AD, Lashley T, Isaacs AM. Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathologica. PMID 31832771 DOI: 10.1007/S00401-019-02104-X |
0.622 |
|
| 2019 |
Vanneste J, Vercruysse T, Boeynaems S, Sicart A, Damme PV, Daelemans D, Bosch LVD. C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport Scientific Reports. 9: 15728. PMID 31673013 DOI: 10.1038/S41598-019-52035-6 |
0.387 |
|
| 2019 |
Boeynaems S, Gitler AD. Axons Gonna Ride 'til They Can't No More. Neuron. 104: 179-181. PMID 31647889 DOI: 10.1016/J.Neuron.2019.09.029 |
0.603 |
|
| 2019 |
Boeynaems S, Holehouse AS, Weinhardt V, Kovacs D, Van Lindt J, Larabell C, Van Den Bosch L, Das R, Tompa PS, Pappu RV, Gitler AD. Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 30926670 DOI: 10.1073/Pnas.1821038116 |
0.562 |
|
| 2018 |
Boeynaems S, Gitler AD. Pour Some Sugar on TDP(-43). Molecular Cell. 71: 649-651. PMID 30193092 DOI: 10.1016/J.Molcel.2018.08.032 |
0.678 |
|
| 2018 |
Bogaert E, Boeynaems S, Kato M, Guo L, Caulfield TR, Steyaert J, Scheveneels W, Wilmans N, Haeck W, Hersmus N, Schymkowitz J, Rousseau F, Shorter J, Callaerts P, Robberecht W, et al. Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity. Cell Reports. 24: 529-537.e4. PMID 30021151 DOI: 10.1016/J.Celrep.2018.06.070 |
0.394 |
|
| 2018 |
Boeynaems S, Gitler AD. Phosphorylation Leads the Way for Protein Aggregate Disassembly. Developmental Cell. 45: 279-281. PMID 29738705 DOI: 10.1016/J.Devcel.2018.04.017 |
0.647 |
|
| 2018 |
Boeynaems S, Alberti S, Fawzi NL, Mittag T, Polymenidou M, Rousseau F, Schymkowitz J, Shorter J, Wolozin B, Van Den Bosch L, Tompa P, Fuxreiter M. Protein Phase Separation: A New Phase in Cell Biology. Trends in Cell Biology. PMID 29602697 DOI: 10.1016/J.Tcb.2018.02.004 |
0.381 |
|
| 2018 |
Boeynaems S, Tompa P, Bosch LVD. Phasing in on the cell cycle. Cell Division. 13: 1-8. PMID 29416553 DOI: 10.1186/S13008-018-0034-4 |
0.381 |
|
| 2018 |
Swinnen B, Bento-Abreu A, Gendron TF, Boeynaems S, Bogaert E, Nuyts R, Timmers M, Scheveneels W, Hersmus N, Wang J, Mizielinska S, Isaacs AM, Petrucelli L, Lemmens R, Van Damme P, et al. A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism. Acta Neuropathologica. PMID 29302778 DOI: 10.1007/S00401-017-1796-5 |
0.373 |
|
| 2017 |
Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, et al. Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Molecular Cell. 65: 1044-1055.e5. PMID 28306503 DOI: 10.1016/J.Molcel.2017.02.013 |
0.396 |
|
| 2016 |
Boeynaems S, Bogaert E, Van Damme P, Van Den Bosch L. Inside out: the role of nucleocytoplasmic transport in ALS and FTLD. Acta Neuropathologica. PMID 27271576 DOI: 10.1007/S00401-016-1586-5 |
0.549 |
|
| 2016 |
Boeynaems S, Bogaert E, Michiels E, Gijselinck I, Sieben A, Jovičić A, De Baets G, Scheveneels W, Steyaert J, Cuijt I, Verstrepen KJ, Callaerts P, Rousseau F, Schymkowitz J, Cruts M, et al. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Scientific Reports. 6: 20877. PMID 26869068 DOI: 10.1038/Srep20877 |
0.782 |
|
| 2015 |
Jovičić A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nature Neuroscience. 18: 1226-9. PMID 26308983 DOI: 10.1038/Nn.4085 |
0.659 |
|
| 2015 |
Gemayel R, Chavali S, Pougach K, Legendre M, Zhu B, Boeynaems S, van der Zande E, Gevaert K, Rousseau F, Schymkowitz J, Babu MM, Verstrepen KJ. Variable Glutamine-Rich Repeats Modulate Transcription Factor Activity. Molecular Cell. 59: 615-27. PMID 26257283 DOI: 10.1016/J.Molcel.2015.07.003 |
0.362 |
|
| 2015 |
Jovičič A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS Nature Neuroscience. 18: 1226-1229. DOI: 10.1038/nn.4085 |
0.76 |
|
| 2012 |
Gemayel R, Cho J, Boeynaems S, Verstrepen KJ. Beyond junk-variable tandem repeats as facilitators of rapid evolution of regulatory and coding sequences. Genes. 3: 461-80. PMID 24704980 DOI: 10.3390/Genes3030461 |
0.314 |
|
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