Dieter Egli - Publications

Affiliations: 
Universität Zürich, Zürich, ZH, Switzerland 

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu S, Wang N, Zuccaro MV, Gerhardt J, Iyyappan R, Scatolin GN, Jiang Z, Baslan T, Koren A, Egli D. DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. Nature Communications. 15: 5247. PMID 38898078 DOI: 10.1038/s41467-024-49565-7  0.79
2024 Georgieva D, Wang N, Taglialatela A, Jerabek S, Reczek CR, Lim PX, Sung J, Du Q, Horiguchi M, Jasin M, Ciccia A, Baer R, Egli D. BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. Cell Reports. 43: 114006. PMID 38554279 DOI: 10.1016/j.celrep.2024.114006  0.592
2024 Edwards MM, Wang N, Massey DJ, Bhatele S, Egli D, Koren A. Incomplete reprogramming of DNA replication timing in induced pluripotent stem cells. Cell Reports. 43: 113664. PMID 38194345 DOI: 10.1016/j.celrep.2023.113664  0.386
2023 Xu S, Wang N, Zuccaro MV, Gerhardt J, Baslan T, Koren A, Egli D. DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. Biorxiv : the Preprint Server For Biology. PMID 38234839 DOI: 10.1101/2023.12.25.573304  0.789
2023 Edwards MM, Wang N, Massey DJ, Egli D, Koren A. Incomplete Reprogramming of DNA Replication Timing in Induced Pluripotent Stem Cells. Biorxiv : the Preprint Server For Biology. PMID 37398435 DOI: 10.1101/2023.06.12.544654  0.396
2023 Wang N, Xu S, Egli D. Replication stress in mammalian embryo development, differentiation, and reprogramming. Trends in Cell Biology. PMID 37202286 DOI: 10.1016/j.tcb.2023.03.015  0.339
2022 González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, ... ... Egli D, et al. Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency. Communications Biology. 5: 779. PMID 35918471 DOI: 10.1038/s42003-022-03696-z  0.406
2022 Palmerola KL, Amrane S, De Los Angeles A, Xu S, Wang N, de Pinho J, Zuccaro MV, Taglialatela A, Massey DJ, Turocy J, Robles A, Subbiah A, Prosser B, Lobo R, Ciccia A, ... ... Egli D, et al. Replication stress impairs chromosome segregation and preimplantation development in human embryos. Cell. PMID 35858625 DOI: 10.1016/j.cell.2022.06.028  0.777
2022 Caballero M, Ge T, Rebelo AR, Seo S, Kim S, Brooks K, Zuccaro M, Kanagaraj R, Vershkov D, Kim D, Smogorzewska A, Smolka M, Benvenisty N, West SC, Egli D, et al. Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Human Molecular Genetics. PMID 35394024 DOI: 10.1093/hmg/ddac082  0.773
2021 Edwards MM, Zuccaro MV, Sagi I, Ding Q, Vershkov D, Benvenisty N, Egli D, Koren A. Delayed DNA replication in haploid human embryonic stem cells. Genome Research. PMID 34810218 DOI: 10.1101/gr.275953.121  0.791
2021 Ding Q, Edwards MM, Wang N, Zhu X, Bracci AN, Hulke ML, Hu Y, Tong Y, Hsiao J, Charvet CJ, Ghosh S, Handsaker RE, Eggan K, Merkle FT, Gerhardt J, ... Egli D, et al. The genetic architecture of DNA replication timing in human pluripotent stem cells. Nature Communications. 12: 6746. PMID 34799581 DOI: 10.1038/s41467-021-27115-9  0.608
2021 Sui L, Xin Y, Du Q, Georgieva D, Diedenhofen G, Haataja L, Su Q, Zuccaro MV, Kim J, Fu J, Xing Y, He Y, Baum D, Goland RS, Wang Y, ... ... Egli D, et al. Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size. Jci Insight. PMID 33529174 DOI: 10.1172/jci.insight.141553  0.772
2020 Zuccaro MV, Xu J, Mitchell C, Marin D, Zimmerman R, Rana B, Weinstein E, King RT, Palmerola KL, Smith ME, Tsang SH, Goland R, Jasin M, Lobo R, Treff N, ... Egli D, et al. Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos. Cell. PMID 33125898 DOI: 10.1016/j.cell.2020.10.025  0.778
2020 Georgieva D, Liu Q, Wang K, Egli D. Detection of base analogs incorporated during DNA replication by nanopore sequencing. Nucleic Acids Research. PMID 32710620 DOI: 10.1093/Nar/Gkaa517  0.391
2020 Paniza T, Deshpande M, Wang N, O'Neil R, Zuccaro MV, Smith ME, Madireddy A, James D, Ecker J, Rosenwaks Z, Egli D, Gerhardt J. Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication. The Journal of Cell Biology. 219. PMID 32673399 DOI: 10.1083/Jcb.201909163  0.785
2020 Gouveia C, Huyser C, Egli D, Pepper MS. Lessons Learned from Somatic Cell Nuclear Transfer. International Journal of Molecular Sciences. 21. PMID 32230814 DOI: 10.3390/ijms21072314  0.303
2020 González BJ, Creusot RJ, Sykes M, Egli D. How Safe Are Universal Pluripotent Stem Cells? Cell Stem Cell. 26: 307-308. PMID 32142661 DOI: 10.1016/J.Stem.2020.02.006  0.373
2020 Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, ... ... Egli D, et al. GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration. Science Translational Medicine. 12. PMID 32051230 DOI: 10.1126/Scitranslmed.Aaw9996  0.335
2019 Romer AI, Singer RA, Sui L, Egli D, Sussel L. Murine Perinatal Beta Cell Proliferation and the Differentiation of Human Stem Cell Derived Insulin Expressing Cells Require NEUROD1. Diabetes. PMID 31519700 DOI: 10.2337/Db19-0117  0.393
2019 Sagi I, De Pinho JC, Zuccaro MV, Atzmon C, Golan-Lev T, Yanuka O, Prosser R, Sadowy A, Perez G, Cabral T, Glaser B, Tsang SH, Goland R, Sauer MV, Lobo R, ... ... Egli D, et al. Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells. Cell Stem Cell. 25: 419-432.e9. PMID 31491396 DOI: 10.1016/J.Stem.2019.06.013  0.776
2019 Nambiar TS, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A. Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant. Nature Communications. 10: 3395. PMID 31363085 DOI: 10.1038/S41467-019-11105-Z  0.435
2019 Kuo T, Damle M, González BJ, Egli D, Lazar MA, Accili D. Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction. Jci Insight. 5. PMID 31120862 DOI: 10.1172/Jci.Insight.128351  0.334
2019 Foo KS, Skowronski AA, Baum D, Firdessa-Fite R, Thams S, Shang L, Creusot RJ, LeDuc CA, Egli D, Leibel RL. Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity. Scientific Reports. 9: 4965. PMID 30899071 DOI: 10.1038/S41598-019-40768-3  0.305
2019 Wang L, De Solis AJ, Goffer Y, Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee JY, Tan J, De Rosa MC, Doege CA, Aaron HL, ... ... Egli D, et al. Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development. Jci Insight. 4. PMID 30728336 DOI: 10.1172/Jci.Insight.123337  0.317
2019 Liu Q, Georgieva DC, Egli D, Wang K. NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data. Bmc Genomics. 20: 78. PMID 30712508 DOI: 10.1186/S12864-018-5372-8  0.303
2018 Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, et al. Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells. Cell Metabolism. PMID 30581122 DOI: 10.1016/J.Cmet.2018.12.005  0.343
2018 Egli D, Zuccaro MV, Kosicki M, Church GM, Bradley A, Jasin M. Inter-homologue repair in fertilized human eggs? Nature. 560: E5-E7. PMID 30089924 DOI: 10.1038/S41586-018-0379-5  0.758
2018 Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, et al. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells. Transplantation. PMID 29781950 DOI: 10.1097/Tp.0000000000002217  0.348
2018 Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S. Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions. Stem Cell Research. 29: 99-102. PMID 29631040 DOI: 10.1016/J.Scr.2018.03.017  0.384
2018 Fischer C, Prosser R, Lobo R, Egli D. Paternal mitochondrial DNA present in human embryos Fertility and Sterility. 110. DOI: 10.1016/J.Fertnstert.2018.07.433  0.361
2017 Sevilla A, Forero E, Zimmer M, Martinez H, Reggio K, Paull D, Egli D, Noggle S. Derivation and characterization of the NYSCFe003-A human embryonic stem cell line. Stem Cell Research. 25: 217-220. PMID 29161648 DOI: 10.1016/J.Scr.2017.10.017  0.386
2017 Chia G, Agudo J, Treff N, Sauer MV, Billing D, Brown BD, Baer R, Egli D. Genomic instability during reprogramming by nuclear transfer is DNA replication dependent. Nature Cell Biology. PMID 28263958 DOI: 10.1038/Ncb3485  0.495
2017 Yamada M, Egli D. Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes Stem Cell Reports. 8: 576-588. PMID 28242217 DOI: 10.1016/J.Stemcr.2017.01.020  0.389
2017 Wang L, Sui L, Panigrahi SK, Meece K, Xin Y, Kim J, Gromada J, Doege CA, Wardlaw SL, Egli D, Leibel RL. PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons. Stem Cell Reports. PMID 28132887 DOI: 10.1016/J.Stemcr.2016.12.021  0.356
2017 Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, LeDuc C, Chung WK, Goland R, Leibel RL, Egli D. iPSC-derived β cells model diabetes due to glucokinase deficiency. The Journal of Clinical Investigation. PMID 28094769 DOI: 10.1172/JCI92775  0.354
2017 Safier LZ, Zuccaro MV, Lobo R, Egli D. Gene editing in haploid human embryonic stem cells using CRISPR/Cas9 Fertility and Sterility. 108. DOI: 10.1016/J.Fertnstert.2017.07.086  0.437
2016 Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, ... ... Egli D, et al. Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome. The Journal of Clinical Investigation. PMID 27941249 DOI: 10.1172/Jci88648  0.327
2016 Burnett LC, LeDuc CA, Sulsona CR, Paull D, Eddiry S, Levy B, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL. Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS. Stem Cell Research. 17: 526-530. PMID 27789403 DOI: 10.1016/J.Scr.2016.08.008  0.409
2016 Sagi I, Egli D, Benvenisty N. Identification and propagation of haploid human pluripotent stem cells. Nature Protocols. 11: 2274-2286. PMID 27763625 DOI: 10.1038/Nprot.2016.145  0.455
2016 Weissbein U, Schachter M, Egli D, Benvenisty N. Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq. Nature Communications. 7: 12144. PMID 27385103 DOI: 10.1038/Ncomms12144  0.385
2016 Wang L, Egli D, Leibel RL. Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 90: 21.5.1-21.5.14. PMID 27367166 DOI: 10.1002/Cphg.3  0.353
2016 Yamada M, Emmanuele V, Sanchez-Quintero MJ, Sun B, Lallos G, Paull D, Zimmer M, Pagett S, Prosser RW, Sauer MV, Hirano M, Egli D. Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes. Cell Stem Cell. PMID 27212703 DOI: 10.1016/J.Stem.2016.04.001  0.339
2016 Stratigopoulos G, Burnett LC, Rausch R, Gill R, Penn DB, Skowronski AA, LeDuc CA, Lanzano AJ, Zhang P, Storm DR, Egli D, Leibel RL. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. The Journal of Clinical Investigation. PMID 27064284 DOI: 10.1172/Jci85526  0.306
2016 Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N. Derivation and differentiation of haploid human embryonic stem cells. Nature. PMID 26982723 DOI: 10.1038/Nature17408  0.502
2015 Kort DH, Chia G, Treff NR, Tanaka AJ, Xing T, Vensand LB, Micucci S, Prosser R, Lobo RA, Sauer MV, Egli D. Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest. Human Reproduction (Oxford, England). PMID 26621855 DOI: 10.1093/Humrep/Dev281  0.418
2015 Agudo J, Ruzo A, Park ES, Sweeney R, Kana V, Wu M, Zhao Y, Egli D, Merad M, Brown BD. GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions. Nature Biotechnology. PMID 26524661 DOI: 10.1038/Nbt.3386  0.324
2015 Yamada M, Byrne J, Egli D. From cloned frogs to patient matched stem cells: induced pluripotency or somatic cell nuclear transfer? Current Opinion in Genetics & Development. 34: 29-34. PMID 26282611 DOI: 10.1016/J.Gde.2015.06.007  0.451
2015 Johannesson B, Sui L, Freytes DO, Creusot RJ, Egli D. Toward beta cell replacement for diabetes. The Embo Journal. 34: 841-55. PMID 25733347 DOI: 10.15252/Embj.201490685  0.33
2015 Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, et al. Differentiation of hypothalamic-like neurons from human pluripotent stem cells. The Journal of Clinical Investigation. 125: 796-808. PMID 25555215 DOI: 10.1172/Jci79220  0.368
2014 Goland R, Egli D. Stem Cell-Derived Beta Cells for Treatment of Type 1 Diabetes? Ebiomedicine. 1: 93-94. PMID 26137512 DOI: 10.1016/J.Ebiom.2014.10.018  0.356
2014 Johannesson B, Sagi I, Gore A, Paull D, Yamada M, Golan-Lev T, Li Z, LeDuc C, Shen Y, Stern S, Xu N, Ma H, Kang E, Mitalipov S, Sauer MV, ... ... Egli D, et al. Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors. Cell Stem Cell. 15: 634-42. PMID 25517467 DOI: 10.1016/J.Stem.2014.10.002  0.491
2014 Bouchi R, Foo KS, Hua H, Tsuchiya K, Ohmura Y, Sandoval PR, Ratner LE, Egli D, Leibel RL, Accili D. FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures. Nature Communications. 5: 4242. PMID 24979718 DOI: 10.1038/Ncomms5242  0.394
2014 Li Y, Wu WH, Hsu CW, Nguyen HV, Tsai YT, Chan L, Nagasaki T, Maumenee IH, Yannuzzi LA, Hoang QV, Hua H, Egli D, Tsang SH. Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1688-97. PMID 24895994 DOI: 10.1038/Mt.2014.100  0.374
2014 Stratigopoulos G, Martin Carli JF, O'Day DR, Wang L, Leduc CA, Lanzano P, Chung WK, Rosenbaum M, Egli D, Doherty DA, Leibel RL. Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice. Cell Metabolism. 19: 767-79. PMID 24807221 DOI: 10.1016/J.Cmet.2014.04.009  0.44
2014 Yamada M, Johannesson B, Sagi I, Burnett LC, Kort DH, Prosser RW, Paull D, Nestor MW, Freeby M, Greenberg E, Goland RS, Leibel RL, Solomon SL, Benvenisty N, Sauer MV, ... Egli D, et al. Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells. Nature. 510: 533-6. PMID 24776804 DOI: 10.1038/Nature13287  0.45
2014 Yang J, Li Y, Chan L, Tsai YT, Wu WH, Nguyen HV, Hsu CW, Li X, Brown LM, Egli D, Sparrow JR, Tsang SH. Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines. Human Molecular Genetics. 23: 3445-55. PMID 24497574 DOI: 10.1093/Hmg/Ddu053  0.347
2014 Shang L, Hua H, Foo K, Martinez H, Watanabe K, Zimmer M, Kahler DJ, Freeby M, Chung W, LeDuc C, Goland R, Leibel RL, Egli D. β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes. 63: 923-33. PMID 24227685 DOI: 10.2337/Db13-0717  0.455
2014 Egli D, Chia G. A protocol for embryonic stem cell derivation by somatic cell nuclear transfer into human oocytes Protocol Exchange. DOI: 10.1038/Protex.2014.013  0.444
2013 Tanaka AJ, Sauer MV, Egli D, Kort DH. Harnessing the stem cell potential: the path to prevent mitochondrial disease. Nature Medicine. 19: 1578-1579. PMID 24309656 DOI: 10.1038/Nm.3422  0.403
2013 Dowdle JA, Mehta M, Kass EM, Vuong BQ, Inagaki A, Egli D, Jasin M, Keeney S. Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. Plos Genetics. 9: e1003945. PMID 24244200 DOI: 10.1371/Journal.Pgen.1003945  0.635
2013 Chia G, Egli D. Connecting the cell cycle with cellular identity. Cellular Reprogramming. 15: 356-366. PMID 24073943 DOI: 10.1089/Cell.2013.0041  0.425
2013 Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, Leduc C, Chung WK, Goland R, Leibel RL, Egli D. iPSC-derived β cells model diabetes due to glucokinase deficiency. The Journal of Clinical Investigation. 123: 3146-53. PMID 23778137 DOI: 10.1172/Jci67638  0.501
2013 Egli D, Bin GCL. Tying replication to cell identity. Nature Reviews Molecular Cell Biology. 14: 326-326. PMID 23698578 DOI: 10.1038/Nrm3593  0.431
2013 Kahler DJ, Ahmad FS, Ritz A, Hua H, Moroziewicz DN, Sproul AA, Dusenberry CR, Shang L, Paull D, Zimmer M, Weiss KA, Egli D, Noggle SA. Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting. Plos One. 8: e59867. PMID 23555815 DOI: 10.1371/Journal.Pone.0059867  0.39
2013 Paull D, Emmanuele V, Weiss KA, Treff N, Stewart L, Hua H, Zimmer M, Kahler DJ, Goland RS, Noggle SA, Prosser R, Hirano M, Sauer MV, Egli D. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants. Nature. 493: 632-7. PMID 23254936 DOI: 10.1038/Nature11800  0.413
2013 Paull D, Emmanuele V, Sauer MV, Hirano M, Egli D. Nuclear genome transfer in human oocytes to prevent transmission of mtDNA mutations Mitochondrion. 13: 898-899. DOI: 10.1016/J.Mito.2013.07.005  0.336
2012 Chan MM, Smith ZD, Egli D, Regev A, Meissner A. Mouse ooplasm confers context-specific reprogramming capacity. Nature Genetics. 44: 978-80. PMID 22902786 DOI: 10.1038/Ng.2382  0.382
2012 Li Y, Tsai YT, Hsu CW, Erol D, Yang J, Wu WH, Davis RJ, Egli D, Tsang SH. Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa. Molecular Medicine (Cambridge, Mass.). 18: 1312-9. PMID 22895806 DOI: 10.2119/Molmed.2012.00242  0.317
2012 Lee JA, Barritt J, Paull D, Martinez H, Egli D, Copperman AB. Developmental potential of late maturing human oocytes after parthenogenetic artificial activation Fertility and Sterility. 98. DOI: 10.1016/J.Fertnstert.2012.07.077  0.34
2011 Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T. BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. Science (New York, N.Y.). 334: 525-8. PMID 22034435 DOI: 10.1126/Science.1209909  0.502
2011 Egli D, Chen AE, Saphier G, Powers D, Alper M, Katz K, Berger B, Goland R, Leibel RL, Melton DA, Eggan K. Impracticality of egg donor recruitment in the absence of compensation. Cell Stem Cell. 9: 293-4. PMID 21982228 DOI: 10.1016/J.Stem.2011.08.002  0.59
2011 Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, ... Egli D, et al. Human oocytes reprogram somatic cells to a pluripotent state. Nature. 478: 70-5. PMID 21979046 DOI: 10.1038/Nature10397  0.467
2011 Egli D, Chen AE, Saphier G, Ichida J, Fitzgerald C, Go KJ, Acevedo N, Patel J, Baetscher M, Kearns WG, Goland R, Leibel RL, Melton DA, Eggan K. Reprogramming within hours following nuclear transfer into mouse but not human zygotes. Nature Communications. 2: 488. PMID 21971503 DOI: 10.1038/Ncomms1503  0.656
2011 Marshall C, Wang GK, Cimetta E, Talchai C, Egli D, Shim JW, Martin I, Ahmad F, Sproul A, Chen T, Fossati V, McKeon D, Smith K, Solomon SL. The New York Stem Cell Foundation: Fifth Annual Translational Stem Cell Research Conference. Annals of the New York Academy of Sciences. 1226: 1-13. PMID 21615750 DOI: 10.1111/J.1749-6632.2011.06038.X  0.358
2010 Egli D, Eggan KC. Recipient cell nuclear factors are required for reprogramming by nuclear transfer Development. 137: 1953-1963. PMID 20463036 DOI: 10.1242/Dev.046151  0.577
2010 Hall ZW, Kahler D, Manganiello M, Egli D, James D, Marolt D, Marlot D, Fasano C, Ichida J, Noggle S, Solomon SL, McKeon D, Smith K, Marshall C. Breaking ground on translational stem cell research. Annals of the New York Academy of Sciences. 1189: E1-15. PMID 20233361 DOI: 10.1111/J.1749-6632.2010.05495.X  0.351
2009 Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, Egli D, Loh KM, Carter AC, Di Giorgio FP, Koszka K, Huangfu D, Akutsu H, Liu DR, Rubin LL, Eggan K. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 5: 491-503. PMID 19818703 DOI: 10.1016/J.Stem.2009.09.012  0.712
2009 Egli D, Sandler VM, Shinohara ML, Cantor H, Eggan K. Reprogramming after chromosome transfer into mouse blastomeres. Current Biology : Cb. 19: 1403-9. PMID 19682906 DOI: 10.1016/J.Cub.2009.06.065  0.666
2009 Zhang K, Li JB, Gao Y, Egli D, Xie B, Deng J, Li Z, Lee JH, Aach J, Leproust EM, Eggan K, Church GM. Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. Nature Methods. 6: 613-8. PMID 19620972 DOI: 10.1038/Nmeth.1357  0.589
2009 Deng J, Shoemaker R, Xie B, Gore A, LeProust EM, Antosiewicz-Bourget J, Egli D, Maherali N, Park IH, Yu J, Daley GQ, Eggan K, Hochedlinger K, Thomson J, Wang W, et al. Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nature Biotechnology. 27: 353-60. PMID 19330000 DOI: 10.1038/Nbt.1530  0.63
2009 Chen AE, Egli D, Niakan K, Deng J, Akutsu H, Yamaki M, Cowan C, Fitz-Gerald C, Zhang K, Melton DA, Eggan K. Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell. 4: 103-6. PMID 19200798 DOI: 10.1016/J.Stem.2008.12.001  0.618
2008 Vardanyan A, Atanesyan L, Egli D, Raja SJ, Steinmann-Zwicky M, Renkawitz-Pohl R, Georgiev O, Schaffner W. Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. Bmc Developmental Biology. 8: 68. PMID 18588663 DOI: 10.1186/1471-213X-8-68  0.54
2008 Egli D, Birkhoff G, Eggan K. Mediators of reprogramming: transcription factors and transitions through mitosis. Nature Reviews. Molecular Cell Biology. 9: 505-16. PMID 18568039 DOI: 10.1038/Nrm2439  0.653
2007 Egli D, Rosains J, Birkhoff G, Eggan K. Developmental reprogramming after chromosome transfer into mitotic mouse zygotes. Nature. 447: 679-85. PMID 17554301 DOI: 10.1038/Nature05879  0.661
2007 Balamurugan K, Egli D, Hua H, Rajaram R, Seisenbacher G, Georgiev O, Schaffner W. Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance Embo Journal. 26: 1035-1044. PMID 17290228 DOI: 10.1038/Sj.Emboj.7601543  0.517
2007 Takeuchi H, Georgiev O, Fetchko M, Kappeler M, Schaffner W, Egli D. In vivo construction of transgenes in Drosophila. Genetics. 175: 2019-28. PMID 17179096 DOI: 10.1534/Genetics.106.065920  0.597
2006 Egli D, Eggan K. Nuclear transfer into mouse oocytes. Journal of Visualized Experiments. 116-116. PMID 18704178 DOI: 10.3791/116  0.646
2006 Yepiskoposyan H, Egli D, Fergestad T, Selvaraj A, Treiber C, Multhaup G, Georgiev O, Schaffner W. Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc. Nucleic Acids Research. 34: 4866-77. PMID 16973896 DOI: 10.1093/Nar/Gkl606  0.552
2006 Egli D, Domènech J, Selvaraj A, Balamurugan K, Hua H, Capdevila M, Georgiev O, Schaffner W, Atrian S. The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 647-58. PMID 16716195 DOI: 10.1111/J.1365-2443.2006.00971.X  0.55
2006 Egli D, Yepiskoposyan H, Selvaraj A, Balamurugan K, Rajaram R, Simons A, Multhaup G, Mettler S, Vardanyan A, Georgiev O, Schaffner W. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification. Molecular and Cellular Biology. 26: 2286-96. PMID 16508004 DOI: 10.1128/Mcb.26.6.2286-2296.2006  0.565
2005 Selvaraj A, Balamurugan K, Yepiskoposyan H, Zhou H, Egli D, Georgiev O, Thiele DJ, Schaffner W. Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. Genes & Development. 19: 891-6. PMID 15833915 DOI: 10.1101/Gad.1301805  0.562
2004 Balamurugan K, Egli D, Selvaraj A, Zhang B, Georgiev O, Schaffner W. Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparison. Biological Chemistry. 385: 597-603. PMID 15318808 DOI: 10.1515/Bc.2004.074  0.584
2004 Egli D, Hafen E, Schaffner W. An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster. Genome Research. 14: 1382-93. PMID 15197166 DOI: 10.1101/Gr.2279804  0.6
2004 Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I. Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. Molecular and Cellular Biology. 24: 4710-9. PMID 15143166 DOI: 10.1128/Mcb.24.11.4710-4719.2004  0.378
2004 Schaffner W, Egli D, Kuppusamy B, Yepiskoposyan H, Selvaraj A, Nagy I, Wang Y, Zhang B, Georgiev O. Heavy metal stress response from insects to mammals Gbm Annual Spring Meeting Mosbach 2004. 2004. DOI: 10.1240/sav_gbm_2004_m_000461  0.453
2003 Egli D, Selvaraj A, Yepiskoposyan H, Zhang B, Hafen E, Georgiev O, Schaffner W. Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. The Embo Journal. 22: 100-8. PMID 12505988 DOI: 10.1093/Emboj/Cdg012  0.575
2001 Zhang B, Egli D, Georgiev O, Schaffner W. The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals. Molecular and Cellular Biology. 21: 4505-14. PMID 11416130 DOI: 10.1128/Mcb.21.14.4505-4514.2001  0.574
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