Maria A. Gandini - Publications

Affiliations: 
University of Calgary, Calgary, Alberta, Canada 
Area:
Calcium Channels

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gandini MA, Zamponi GW. Opening the K3.1 gates: A therapeutic strategy for progressive myoclonus epilepsy type 7? Cell Reports. Medicine. 5: 101425. PMID 38382469 DOI: 10.1016/j.xcrm.2024.101425  0.49
2023 Ferron L, Gandini MA, Zamponi GW. Fighting pain: the structure of gabapentin and its binding site in the Caαδ subunit. Nature Structural & Molecular Biology. 30: 717-719. PMID 37286823 DOI: 10.1038/s41594-023-01013-8  0.397
2023 Harding EK, Souza IA, Gandini MA, Gadotti VM, Ali MY, Huang S, Antunes FTT, Trang T, Zamponi GW. Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol. British Journal of Pharmacology. PMID 36647671 DOI: 10.1111/bph.16035  0.65
2022 Gambeta E, Gandini MA, Souza IA, Zamponi GW. CaV3.2 calcium channels contribute to trigeminal neuralgia. Pain. PMID 35467587 DOI: 10.1097/j.pain.0000000000002651  0.786
2021 Gandini MA, Souza IA, Khullar A, Gambeta E, Zamponi GW. Correction to: Regulation of Ca3.2 channels by the receptor for activated C kinase 1 (Rack-1). Pflugers Archiv : European Journal of Physiology. PMID 34674025 DOI: 10.1007/s00424-021-02633-z  0.77
2021 Gandini MA, Souza IA, Khullar A, Gambeta E, Zamponi GW. Regulation of Ca3.2 channels by the receptor for activated C kinase 1 (Rack-1). Pflugers Archiv : European Journal of Physiology. PMID 34623515 DOI: 10.1007/s00424-021-02631-1  0.795
2021 Souza IA, Gandini MA, Zamponi GW. Splice-variant specific effects of a CACNA1H mutation associated with writer's cramp. Molecular Brain. 14: 145. PMID 34544471 DOI: 10.1186/s13041-021-00861-z  0.659
2021 Gandini MA, Zamponi GW. Voltage-gated calcium channel nanodomains: molecular composition and function. The Febs Journal. PMID 33576127 DOI: 10.1111/febs.15759  0.675
2021 Gandini MA, Souza IA, Ferron L, Innes AM, Zamponi GW. The de novo CACNA1A pathogenic variant Y1384C associated with hemiplegic migraine, early onset cerebellar atrophy and developmental delay leads to a loss of Cav2.1 channel function. Molecular Brain. 14: 27. PMID 33557884 DOI: 10.1186/s13041-021-00745-2  0.609
2021 Huang M, Nibbeling EAR, Lagrand TJ, Souza IA, Groen JL, Gandini MA, Zhang FX, Koelman JHTM, Adir N, Sinke RJ, Zamponi GW, Tijssen MAJ, Verbeek DS. Rare functional missense variants in CACNA1H: What can we learn from Writer's cramp? Molecular Brain. 14: 18. PMID 33478561 DOI: 10.1186/s13041-021-00736-3  0.553
2021 Gambeta E, Gandini MA, Souza IA, Ferron L, Zamponi GW. A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2.1 channels. Molecular Brain. 14: 4. PMID 33413531 DOI: 10.1186/s13041-020-00725-y  0.804
2020 Ficelova V, Souza IA, Cmarko L, Gandini MA, Stringer RN, Zamponi GW, Weiss N. Functional identification of potential non-canonical N-glycosylation sites within Ca3.2 T-type calcium channels. Molecular Brain. 13: 149. PMID 33176830 DOI: 10.1186/s13041-020-00697-z  0.656
2020 Huang J, Gandini MA, Chen L, M'Dahoma S, Stemkowski PL, Chung H, Muruve DA, Zamponi GW. Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk. Cell Reports. 33: 108233. PMID 33027646 DOI: 10.1016/j.celrep.2020.108233  0.397
2020 Nam Y, Ryu KD, Jang C, Moon YH, Kim M, Ko D, Chung KS, Gandini MA, Lee KT, Zamponi GW, Lee JY. Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers. Bioorganic & Medicinal Chemistry. 115491. PMID 32327350 DOI: 10.1016/J.Bmc.2020.115491  0.626
2020 Huang J, Gandini MA, M’dahoma S, Muruve DA, Zamponi GW. Regulation of pain signaling by the innate immune system Proceedings For Annual Meeting of the Japanese Pharmacological Society. 93: 2-S24-1. DOI: 10.1254/jpssuppl.93.0_2-s24-1  0.39
2019 Gandini MA, Souza IA, Raval D, Xu J, Pan YX, Zamponi GW. Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors. Molecular Brain. 12: 98. PMID 31775826 DOI: 10.1186/S13041-019-0524-6  0.645
2019 Souza IA, Gandini MA, Zhang FX, Mitchell WG, Matsumoto J, Lerner J, Pierson TM, Zamponi GW. Pathogenic Cav3.2 channel mutation in a child with primary generalized epilepsy. Molecular Brain. 12: 86. PMID 31651342 DOI: 10.1186/S13041-019-0509-5  0.602
2019 Aygün Cevher H, Schaller D, Gandini MA, Kaplan O, Gambeta E, Zhang FX, Çelebier M, Tahir MN, Zamponi GW, Wolber G, Gündüz MG. Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels. Bioorganic Chemistry. 91: 103187. PMID 31419643 DOI: 10.1016/J.Bioorg.2019.103187  0.77
2019 Gandini MA, Souza IA, Fan J, Li K, Wang D, Zamponi GW. Interactions of Rabconnectin-3 with Cav2 calcium channels. Molecular Brain. 12: 62. PMID 31253182 DOI: 10.1186/S13041-019-0483-Y  0.671
2019 Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, et al. De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias. American Journal of Human Genetics. 104: 562. PMID 30849329 DOI: 10.1016/j.ajhg.2019.02.015  0.385
2019 Garcia-Caballero A, Gandini MA, Huang S, Chen L, Souza IA, Dang YL, Stutts MJ, Zamponi GW. Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC. Molecular Brain. 12: 12. PMID 30736831 DOI: 10.1186/S13041-019-0433-8  0.717
2018 Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, et al. De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias. American Journal of Human Genetics. PMID 30343943 DOI: 10.1016/j.ajhg.2018.09.006  0.592
2018 Bellampalli SS, Ji Y, Moutal A, Cai S, Wijeratne EMK, Gandini MA, Yu J, Chefdeville A, Dorame A, Chew LA, Madura CL, Luo S, Molnar G, Khanna M, Streicher JM, et al. Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Pain. PMID 30169422 DOI: 10.1097/J.Pain.0000000000001385  0.613
2017 Sandoval A, Duran P, Gandini MA, Andrade A, Almanza A, Kaja S, Felix R. Regulation of L-type CaV1.3 channel activity and insulin secretion by the cGMP-PKG signaling pathway. Cell Calcium. 66: 1-9. PMID 28807144 DOI: 10.1016/J.Ceca.2017.05.008  0.589
2017 Fan J, Gandini MA, Zhang FX, Chen L, Souza IA, Zamponi GW. Down-regulation of T-type Cav3.2 channels by hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1): evidence of a signaling complex. Channels (Austin, Tex.). 0. PMID 28467171 DOI: 10.1080/19336950.2017.1326233  0.71
2016 Fan J, Stemkowski PL, Gandini MA, Black SA, Zhang Z, Souza IA, Chen L, Zamponi GW. Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Frontiers in Cellular Neuroscience. 10: 74. PMID 27047338 DOI: 10.3389/Fncel.2016.00074  0.597
2015 Souza IA, Gandini MA, Wan MM, Zamponi GW. Two heterozygous Cav3.2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects. Pflugers Archiv : European Journal of Physiology. PMID 26706850 DOI: 10.1007/S00424-015-1776-3  0.71
2015 Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F. RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13133-47. PMID 26400943 DOI: 10.1523/Jneurosci.0658-15.2015  0.683
2015 López Soto EJ, Agosti F, Cabral A, Mustafa ER, Damonte VM, Gandini MA, Rodríguez S, Castrogiovanni D, Felix R, Perelló M, Raingo J. Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons. The Journal of General Physiology. 146: 205-19. PMID 26283199 DOI: 10.1085/Jgp.201511383  0.466
2015 Gandini MA, Felix R. Molecular and functional interplay of voltage-gated Ca(2+) channels with the cytoskeleton. Current Molecular Pharmacology. 8: 69-80. PMID 25966702 DOI: 10.2174/1874467208666150507094252  0.605
2015 Gandini MA, Sandoval A, Felix R. Toxins targeting voltage-activated Ca2+ channels and their potential biomedical applications. Current Topics in Medicinal Chemistry. 15: 604-16. PMID 25714378 DOI: 10.2174/1568026615666150225112605  0.575
2015 Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F. RIM1/2-mediated facilitation of cav1.4 channel opening is required for Ca2+-stimulated release in mouse rod photoreceptors Journal of Neuroscience. 35: 13133-13147. DOI: 10.1523/JNEUROSCI.0627-15.2015  0.619
2015 Gandini MA, Felix R. Molecular and Functional Interplay of Voltage-Gated Ca2+ Channels with the Cytoskeleton Current Molecular Pharmacology. 8: 69-80.  0.502
2015 Gandini MA, Sandoval A, Felix R. Toxins targeting voltage-activated Ca2+ channels and their potential biomedical applications Current Topics in Medicinal Chemistry. 15: 604-616.  0.476
2014 Gandini MA, Sandoval A, Zamponi GW, Felix R. The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels. Channels (Austin, Tex.). 8: 452-7. PMID 25483588 DOI: 10.4161/19336950.2014.949162  0.697
2014 Canto-Bustos M, Loeza-Alcocer E, González-Ramírez R, Gandini MA, Delgado-Lezama R, Felix R. Functional expression of T-type Ca2+ channels in spinal motoneurons of the adult turtle. Plos One. 9: e108187. PMID 25255145 DOI: 10.1371/Journal.Pone.0108187  0.571
2014 Gandini MA, Sandoval A, Felix R. Whole-cell patch-clamp recording of recombinant voltage-sensitive Ca2+ channels heterologously expressed in HEK-293 cells. Cold Spring Harbor Protocols. 2014: 396-401. PMID 24692488 DOI: 10.1101/Pdb.Prot073213  0.6
2014 Gandini MA, Sandoval A, Felix R. Whole-cell patch-clamp recordings of Ca2+ currents from isolated neonatal mouse dorsal root ganglion (DRG) neurons. Cold Spring Harbor Protocols. 2014: 389-95. PMID 24692487 DOI: 10.1101/Pdb.Prot073205  0.433
2014 Gandini MA, Sandoval A, Felix R. Patch-clamp recording of voltage-sensitive Ca2+ channels. Cold Spring Harbor Protocols. 2014: 329-5. PMID 24692484 DOI: 10.1101/Pdb.Top066092  0.517
2014 Gandini MA, Henríquez DR, Grimaldo L, Sandoval A, Altier C, Zamponi GW, Felix R, González-Billault C. CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation. PflüGers Archiv : European Journal of Physiology. 466: 2113-26. PMID 24566975 DOI: 10.1007/S00424-014-1476-4  0.678
2013 Garza-López E, González-Ramírez R, Gandini MA, Sandoval A, Felix R. The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels. Cephalalgia : An International Journal of Headache. 33: 398-407. PMID 23430985 DOI: 10.1177/0333102412475236  0.519
2012 Gandini MA. Channeling headache: novel findings in the study of Ca(2+)-channels and FHM-1. Channels (Austin, Tex.). 6: 414-5. PMID 22991044 DOI: 10.4161/Chan.22146  0.458
2012 Garza-López E, Sandoval A, González-Ramírez R, Gandini MA, Van den Maagdenberg A, De Waard M, Felix R. Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels. Biochimica Et Biophysica Acta. 1822: 1238-46. PMID 22549042 DOI: 10.1016/J.Bbadis.2012.04.008  0.574
2012 Gandini MA, Felix R. Functional interactions between voltage-gated Ca(2+) channels and Rab3-interacting molecules (RIMs): new insights into stimulus-secretion coupling. Biochimica Et Biophysica Acta. 1818: 551-8. PMID 22198390 DOI: 10.1016/J.Bbamem.2011.12.011  0.566
2011 Gandini MA, Sandoval A, González-Ramírez R, Mori Y, de Waard M, Felix R. Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release. The Journal of Biological Chemistry. 286: 15757-65. PMID 21402706 DOI: 10.1074/Jbc.M110.187757  0.542
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