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Helen McNeill, Ph.D. - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Website:
http://www.mshri.on.ca/mcneill/
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70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chang YJ, Zhou L, Binari R, Manoukian A, Mak T, McNeill H, Stambolic V. Correction: The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila. Plos One. 16: e0252252. PMID 34015029 DOI: 10.1371/journal.pone.0252252  0.36
2020 Rao-Bhatia A, Zhu M, Yin WC, Coquenlorge S, Zhang X, Woo J, Sun Y, Dean CH, Liu A, Hui CC, Shivdasani RA, McNeill H, Hopyan S, Kim TH. Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development. Developmental Cell. 52: 647-658.e6. PMID 32155439 DOI: 10.1016/J.Devcel.2020.02.003  0.48
2020 Reginensi A, Jain S, Humphreys B, Shen J, Hodzic D, Wrana J, McNeill H. Abstract IA25: Adult deletion of Lats1/2 leads to sarcomatoid renal cell carcinoma Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-Ia25  0.44
2019 Zhang H, Bagherie-Lachidan M, Badouel C, Enderle L, Peidis P, Bremner R, Kuure S, Jain S, McNeill H. FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling. Developmental Cell. PMID 30853441 DOI: 10.1016/J.Devcel.2019.02.004  0.44
2019 Rao-Bhatia A, Coquenlorge-Gallon S, Yin W, Zhang X, Zhu M, Hui C, Hopyan S, McNeill H, Kim T. Uncovering the role of planar cell polarity during intestinal morphogenesis International Journal of Digestive Diseases. 5. DOI: 10.4172/2161-069X-C6-079  0.48
2018 Wang X, Liu H, Zhu M, Cao C, Xu Z, Tsatskis Y, Lau K, Kuok C, Filleter T, McNeill H, Simmons CA, Hopyan S, Sun Y. Mechanical stability of the cell nucleus: roles played by the cytoskeleton in nuclear deformation and strain recovery. Journal of Cell Science. PMID 29777038 DOI: 10.1242/Jcs.209627  0.48
2018 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EM, Feitz WF, van Eerde AM, Lefebvre V, Knoers NV, Tabatabaei M, Schulz H, McNeill H, Schaefer F, et al. Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney International. PMID 29459093 DOI: 10.1016/J.Kint.2017.11.026  0.44
2018 Hoshi M, Reginensi A, Joens MS, Fitzpatrick JAJ, McNeill H, Jain S. Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion. Journal of the American Society of Nephrology : Jasn. PMID 29326158 DOI: 10.1681/Asn.2017040380  0.44
2016 Delanoue R, Meschi E, Agrawal N, Mauri A, Tsatskis Y, McNeill H, Léopold P. Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor. Science (New York, N.Y.). 353: 1553-1556. PMID 27708106 DOI: 10.1126/Science.Aaf8430  0.44
2016 McNeill H, Reginensi A. Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation. Journal of the American Society of Nephrology : Jasn. PMID 27647853 DOI: 10.1681/Asn.2016060611  0.44
2016 Reginensi A, Enderle L, Gregorieff A, Johnson RL, Wrana JL, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nature Communications. 7: 12309. PMID 27480037 DOI: 10.1038/Ncomms12309  0.44
2016 Chang YJ, Zhou L, Binari R, Manoukian A, Mak T, McNeill H, Stambolic V. The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila. Plos One. 11: e0152259. PMID 27015411 DOI: 10.1371/Journal.Pone.0152259  0.36
2016 Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, ... ... McNeill H, et al. FAT1 mutations cause a glomerulotubular nephropathy. Nature Communications. 7: 10822. PMID 26905694 DOI: 10.1038/Ncomms10822  0.44
2016 Chiu CW, Monat C, Robitaille M, Lacomme M, Daulat AM, Macleod G, McNeill H, Cayouette M, Angers S. SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex. Developmental Cell. 36: 50-62. PMID 26766442 DOI: 10.1016/J.Devcel.2015.12.016  0.44
2015 Reginensi A, Hoshi M, Boualia SK, Bouchard M, Jain S, McNeill H. Yap and Taz are required for Ret-dependent urinary tract morphogenesis. Development (Cambridge, England). 142: 2696-703. PMID 26243870 DOI: 10.1242/Dev.122044  0.44
2015 Bagherie-Lachidan M, Reginensi A, Zaveri HP, Scott DA, Helmbacher F, McNeill H. Stromal Fat4 acts non-autonomously with Dachsous1/2 to restrict the nephron progenitor pool. Development (Cambridge, England). PMID 26116661 DOI: 10.1242/Dev.122648  0.44
2015 Schwartzman M, Reginensi A, Wong JS, Basgen JM, Meliambro K, Nicholas SB, D'Agati V, McNeill H, Campbell KN. Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure. Journal of the American Society of Nephrology : Jasn. PMID 26015453 DOI: 10.1681/Asn.2014090916  0.44
2015 Sugiyama Y, Shelley EJ, Badouel C, McNeill H, McAvoy JW. Atypical cadherin fat1 is required for lens epithelial cell polarity and proliferation but not for fiber differentiation Investigative Ophthalmology and Visual Science. 56: 4099-4107. DOI: 10.1167/iovs.15-17008  0.44
2014 Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, Yau N, Bietenhader M, Shanbhag R, Jurisicova A, Brill JA, McQuibban GA, McNeill H. The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell. 158: 1293-308. PMID 25215488 DOI: 10.1016/J.Cell.2014.07.036  0.44
2014 Avet-Rochex A, Carvajal N, Christoforou CP, Yeung K, Maierbrugger KT, Hobbs C, Lalli G, Cagin U, Plachot C, McNeill H, Bateman JM. Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control. Plos Genetics. 10: e1004624. PMID 25210733 DOI: 10.1371/Journal.Pgen.1004624  0.44
2014 Zakaria S, Mao Y, Kuta A, Ferreira de Sousa C, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH. Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity. Current Biology : Cb. 24: 1620-7. PMID 24998526 DOI: 10.1016/J.Cub.2014.05.067  0.44
2014 Belozerov VE, Ratkovic S, McNeill H, Hilliker AJ, McDermott JC. In vivo interaction proteomics reveal a novel p38 mitogen-activated protein kinase/Rack1 pathway regulating proteostasis in Drosophila muscle. Molecular and Cellular Biology. 34: 474-84. PMID 24277934 DOI: 10.1128/Mcb.00824-13  0.44
2014 Bossuyt W, Chen CL, Chen Q, Sudol M, McNeill H, Pan D, Kopp A, Halder G. An evolutionary shift in the regulation of the Hippo pathway between mice and flies. Oncogene. 33: 1218-28. PMID 23563179 DOI: 10.1038/Onc.2013.82  0.44
2013 Enderle L, McNeill H. Hippo gains weight: added insights and complexity to pathway control. Science Signaling. 6: re7. PMID 24106343 DOI: 10.1126/Scisignal.2004208  0.44
2013 Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, ... ... McNeill H, et al. Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nature Genetics. 45: 1300-8. PMID 24056717 DOI: 10.1038/Ng.2765  0.44
2013 Sharma P, McNeill H. Regulation of long-range planar cell polarity by Fat-Dachsous signaling. Development (Cambridge, England). 140: 3869-81. PMID 23946440 DOI: 10.1242/Dev.094730  0.44
2013 Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. Plos Genetics. 9: e1003380. PMID 23555292 DOI: 10.1371/Journal.Pgen.1003380  0.44
2013 Brooun M, Manoukian A, Shimizu H, Bode HR, McNeill H. Organizer formation in Hydra is disrupted by thalidomide treatment. Developmental Biology. 378: 51-63. PMID 23531412 DOI: 10.1016/J.Ydbio.2013.03.013  0.44
2013 Sharma P, McNeill H. Fat and Dachsous cadherins. Progress in Molecular Biology and Translational Science. 116: 215-35. PMID 23481197 DOI: 10.1016/B978-0-12-394311-8.00010-8  0.44
2013 Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim D, Pawson T, Wrana J, McNeill H. No major change in apoptosis or proliferation in Yap mutant kidneys. Plos Genetics. DOI: 10.1371/Journal.Pgen.1003380.G005  0.44
2012 Avet-Rochex A, Kaul AK, Gatt AP, McNeill H, Bateman JM. Concerted control of gliogenesis by InR/TOR and FGF signalling in the Drosophila post-embryonic brain. Development (Cambridge, England). 139: 2763-72. PMID 22745312 DOI: 10.1242/Dev.074179  0.44
2012 Saburi S, Hester I, Goodrich L, McNeill H. Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity. Development (Cambridge, England). 139: 1806-20. PMID 22510986 DOI: 10.1242/Dev.077461  0.44
2012 Daulat AM, Luu O, Sing A, Zhang L, Wrana JL, McNeill H, Winklbauer R, Angers S. Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. Molecular and Cellular Biology. 32: 173-85. PMID 22037766 DOI: 10.1128/Mcb.06320-11  0.44
2011 McNeill H, Sudol M, Halder G, Strano S, Blandino G, Shaul Y. The Hippo tumor suppressor pathway: a report on 'the Second Workshop On The Hippo tumor suppressor pathway'. Cell Death and Differentiation. 18: 1388-90. PMID 21566666 DOI: 10.1038/Cdd.2011.61  0.44
2011 Badouel C, McNeill H. SnapShot: The hippo signaling pathway. Cell. 145: 484-484.e1. PMID 21529719 DOI: 10.1016/J.Cell.2011.04.009  0.44
2011 Walker J, Kwon SY, Badenhorst P, East P, McNeill H, Svejstrup JQ. Role of elongator subunit Elp3 in Drosophila melanogaster larval development and immunity. Genetics. 187: 1067-75. PMID 21288872 DOI: 10.1534/Genetics.110.123893  0.44
2010 McNeill H, Woodgett JR. When pathways collide: collaboration and connivance among signalling proteins in development. Nature Reviews. Molecular Cell Biology. 11: 404-13. PMID 20461097 DOI: 10.1038/Nrm2902  0.44
2010 Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L. The Hippo pathway regulates Wnt/beta-catenin signaling. Developmental Cell. 18: 579-91. PMID 20412773 DOI: 10.1016/J.Devcel.2010.03.007  0.44
2010 McNeill H. Planar cell polarity: keeping hairs straight is not so simple. Cold Spring Harbor Perspectives in Biology. 2: a003376. PMID 20182624 DOI: 10.1101/Cshperspect.A003376  0.44
2010 Bagherie-Lachidan M, McNeill H. What drives cyst formation in PKD? Journal of the American Society of Nephrology : Jasn. 21: 200-2. PMID 20075067 DOI: 10.1681/Asn.2009121261  0.44
2009 Badouel C, Garg A, McNeill H. Herding Hippos: regulating growth in flies and man. Current Opinion in Cell Biology. 21: 837-43. PMID 19846288 DOI: 10.1016/J.Ceb.2009.09.010  0.44
2009 McNeill H. Planar cell polarity and the kidney. Journal of the American Society of Nephrology : Jasn. 20: 2104-11. PMID 19762494 DOI: 10.1681/Asn.2008111173  0.44
2009 Sopko R, McNeill H. The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity. Current Opinion in Cell Biology. 21: 717-23. PMID 19679459 DOI: 10.1016/J.Ceb.2009.07.001  0.44
2009 Sopko R, Silva E, Clayton L, Gardano L, Barrios-Rodiles M, Wrana J, Varelas X, Arbouzova NI, Shaw S, Saburi S, Matakatsu H, Blair S, McNeill H. Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown. Current Biology : Cb. 19: 1112-7. PMID 19540118 DOI: 10.1016/J.Cub.2009.05.049  0.44
2009 Amin N, Khan A, St Johnston D, Tomlinson I, Martin S, Brenman J, McNeill H. LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. Proceedings of the National Academy of Sciences of the United States of America. 106: 8941-6. PMID 19443685 DOI: 10.1073/Pnas.0812469106  0.44
2009 Badouel C, Gardano L, Amin N, Garg A, Rosenfeld R, Le Bihan T, McNeill H. The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Developmental Cell. 16: 411-20. PMID 19289086 DOI: 10.1016/J.Devcel.2009.01.010  0.44
2009 Bacallao RL, McNeill H. Cystic kidney diseases and planar cell polarity signaling. Clinical Genetics. 75: 107-17. PMID 19215242 DOI: 10.1111/J.1399-0004.2008.01148.X  0.44
2009 Badouel C, McNeill H. Apical junctions and growth control in Drosophila. Biochimica Et Biophysica Acta. 1788: 755-60. PMID 18952051 DOI: 10.1016/J.Bbamem.2008.08.026  0.44
2008 Arbouzova N, McNeill H. Visualization of PCP defects in the eye and wing of Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 469: 127-40. PMID 19109708 DOI: 10.1007/978-1-60327-469-2_11  0.44
2008 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nature Genetics. 40: 1010-5. PMID 18604206 DOI: 10.1038/Ng.179  0.44
2008 McNeill H, Craig GM, Bateman JM. Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila. Genetics. 179: 843-53. PMID 18505882 DOI: 10.1534/Genetics.107.083097  0.44
2006 Silva E, Tsatskis Y, Gardano L, Tapon N, McNeill H. The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Current Biology : Cb. 16: 2081-9. PMID 16996266 DOI: 10.1016/J.Cub.2006.09.004  0.44
2006 Bateman JM, McNeill H. Insulin/IGF signalling in neurogenesis. Cellular and Molecular Life Sciences : Cmls. 63: 1701-5. PMID 16786222 DOI: 10.1007/S00018-006-6036-4  0.44
2005 Leevers SJ, McNeill H. Controlling the size of organs and organisms. Current Opinion in Cell Biology. 17: 604-9. PMID 16226450 DOI: 10.1016/J.Ceb.2005.09.008  0.44
2005 Bilioni A, Craig G, Hill C, McNeill H. Iroquois transcription factors recognize a unique motif to mediate transcriptional repression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 14671-6. PMID 16203991 DOI: 10.1073/Pnas.0502480102  0.44
2005 Bateman JM, McNeill H. Seeing in color--warts and all. Developmental Cell. 9: 441-2. PMID 16198284 DOI: 10.1016/J.Devcel.2005.09.007  0.44
2005 Saburi S, McNeill H. Organising cells into tissues: new roles for cell adhesion molecules in planar cell polarity. Current Opinion in Cell Biology. 17: 482-8. PMID 16099635 DOI: 10.1016/J.Ceb.2005.08.011  0.44
2005 Srinivasan S, Armstrong JA, Deuring R, Dahlsveen IK, McNeill H, Tamkun JW. The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II. Development (Cambridge, England). 132: 1623-35. PMID 15728673 DOI: 10.1242/Dev.01713  0.44
2004 Bateman JM, McNeill H. Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila. Cell. 119: 87-96. PMID 15454083 DOI: 10.1016/J.Cell.2004.08.028  0.44
2004 Fanto M, McNeill H. Planar polarity from flies to vertebrates. Journal of Cell Science. 117: 527-33. PMID 14730010 DOI: 10.1242/Jcs.00973  0.44
2003 McNeill H. Stuck without Traffic Jam. Nature Cell Biology. 5: 948-9. PMID 14593415 DOI: 10.1038/Ncb1103-948  0.44
2003 Ma D, Yang CH, McNeill H, Simon MA, Axelrod JD. Fidelity in planar cell polarity signalling. Nature. 421: 543-7. PMID 12540853 DOI: 10.1038/Nature01366  0.44
2002 Axelrod JD, McNeill H. Coupling planar cell polarity signaling to morphogenesis. Thescientificworldjournal. 2: 434-54. PMID 12806028 DOI: 10.1100/Tsw.2002.105  0.44
2000 Jordan KC, Clegg NJ, Blasi JA, Morimoto AM, Sen J, Stein D, McNeill H, Deng WM, Tworoger M, Ruohola-Baker H. The homeobox gene mirror links EGF signalling to embryonic dorso-ventral axis formation through notch activation. Nature Genetics. 24: 429-33. PMID 10742112 DOI: 10.1038/74294  0.44
1999 Yang CH, Simon MA, McNeill H. mirror controls planar polarity and equator formation through repression of fringe expression and through control of cell affinities. Development (Cambridge, England). 126: 5857-66. PMID 10572059  0.44
1997 McNeill H, Yang CH, Brodsky M, Ungos J, Simon MA. mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. Genes & Development. 11: 1073-82. PMID 9136934 DOI: 10.1101/Gad.11.8.1073  0.44
1996 Allard JD, Chang HC, Herbst R, McNeill H, Simon MA. The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf. Development (Cambridge, England). 122: 1137-46. PMID 8620840  0.44
1993 McNeill H, Ryan TA, Smith SJ, Nelson WJ. Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion. The Journal of Cell Biology. 120: 1217-26. PMID 8436592 DOI: 10.1083/Jcb.120.5.1217  0.44
1992 Nelson WJ, Wilson R, Wollner D, Mays R, McNeill H, Siemers K. Regulation of epithelial cell polarity: a view from the cell surface. Cold Spring Harbor Symposia On Quantitative Biology. 57: 621-30. PMID 1339699 DOI: 10.1101/Sqb.1992.057.01.068  0.44
1990 Cassimeris L, McNeill H, Zigmond SH. Chemoattractant-stimulated polymorphonuclear leukocytes contain two populations of actin filaments that differ in their spatial distributions and relative stabilities. The Journal of Cell Biology. 110: 1067-75. PMID 2324192 DOI: 10.1083/Jcb.110.4.1067  0.44
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