Year |
Citation |
Score |
2024 |
Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, ... ... LaFerla FM, et al. Genetic diversity promotes resilience in a mouse model of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38426371 DOI: 10.1002/alz.13753 |
0.343 |
|
2023 |
Terron HM, Parikh SJ, Abdul-Hay SO, Sahara T, Kang D, Dickson DW, Saftig P, LaFerla FM, Lane S, Leissring MA. Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis. Research Square. PMID 37961253 DOI: 10.21203/rs.3.rs-3464352/v1 |
0.716 |
|
2023 |
Terron HM, Maranan DS, Burgard LA, LaFerla FM, Lane S, Leissring MA. A Dual-Function "TRE-Lox" System for Genetic Deletion or Reversible, Titratable, and Near-Complete Downregulation of Cathepsin D. International Journal of Molecular Sciences. 24. PMID 37047718 DOI: 10.3390/ijms24076745 |
0.579 |
|
2023 |
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, ... ... LaFerla FM, et al. A Trem2 mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques. Molecular Neurodegeneration. 18: 12. PMID 36803190 DOI: 10.1186/s13024-023-00598-4 |
0.533 |
|
2022 |
Jong Huat T, Onraet T, Camats-Perna J, Newcombe EA, Ngo KC, Sue AN, Mirzaei M, LaFerla FM, Medeiros R. Deletion of MyD88 in astrocytes prevents β-amyloid-induced neuropathology in mice. Glia. PMID 36271704 DOI: 10.1002/glia.24285 |
0.446 |
|
2022 |
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, ... ... LaFerla FM, et al. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease. Frontiers in Neuroscience. 15: 785276. PMID 35140584 DOI: 10.3389/fnins.2021.785276 |
0.627 |
|
2021 |
Lin X, Chen L, Baglietto-Vargas D, Kamalipour P, Ye Q, LaFerla FM, Nitz DA, Holmes TC, Xu X. Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. Neurobiology of Disease. 162: 105562. PMID 34838667 DOI: 10.1016/j.nbd.2021.105562 |
0.441 |
|
2021 |
Trujillo-Estrada L, Vanderklish PW, Nguyen MMT, Kuang RR, Nguyen C, Huynh E, da Cunha C, Javonillo DI, Forner S, Martini AC, Sarraf ST, Simmon VF, Baglietto-Vargas D, LaFerla FM. SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 34738197 DOI: 10.1007/s13311-021-01143-1 |
0.401 |
|
2021 |
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, ... ... LaFerla FM, et al. Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease. Scientific Data. 8: 270. PMID 34654824 DOI: 10.1038/s41597-021-01054-y |
0.561 |
|
2021 |
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, ... ... LaFerla FM, et al. Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology. Nature Communications. 12: 2421. PMID 33893290 DOI: 10.1038/s41467-021-22624-z |
0.602 |
|
2021 |
Trujillo-Estrada L, Sanchez-Mejias E, Sanchez-Varo R, Garcia-Leon JA, Nuñez-Diaz C, Davila JC, Vitorica J, LaFerla FM, Moreno-Gonzalez I, Gutierrez A, Baglietto-Vargas D. Animal and Cellular Models of Alzheimer's Disease: Progress, Promise, and Future Approaches. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10738584211001753. PMID 33769131 DOI: 10.1177/10738584211001753 |
0.374 |
|
2021 |
Oka S, Leon J, Sakumi K, Abolhassani N, Sheng Z, Tsuchimoto D, LaFerla FM, Nakabeppu Y. MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis. Scientific Reports. 11: 5819. PMID 33758207 DOI: 10.1038/s41598-021-84640-9 |
0.428 |
|
2020 |
Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, ... LaFerla FM, et al. Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD. Alzheimer's & Dementia (New York, N. Y.). 6: e12110. PMID 33283040 DOI: 10.1002/trc2.12110 |
0.584 |
|
2020 |
Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging Cell. e13118. PMID 32087004 DOI: 10.1111/Acel.13118 |
0.376 |
|
2019 |
Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, ... ... LaFerla FM, et al. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific Reports. 9: 15936. PMID 31685865 DOI: 10.1038/S41598-019-52324-0 |
0.567 |
|
2019 |
Cadete Martini A, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz CJ, McQuade A, Danhash E, Phan J, Javonillo D, Ha JV, Tram M, Trujillo-Estrada L, da Cunha C, Ager RR, Davila JC, Kitazawa M, ... ... LaFerla FM, et al. Amyloid-beta impairs TOM1-mediated IL-1R1 signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570577 DOI: 10.1073/Pnas.1914088116 |
0.668 |
|
2019 |
Trujillo-Estrada L, Nguyen C, da Cunha C, Cai L, Forner S, Martini AC, Ager RR, Prieto GA, Cotman CW, Baglietto-Vargas D, LaFerla FM. Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models. Aging Cell. e12919. PMID 30809950 DOI: 10.1111/Acel.12919 |
0.474 |
|
2019 |
Stimmell AC, Baglietto-Vargas D, Moseley SC, Lapointe V, Thompson LM, LaFerla FM, McNaughton BL, Wilber AA. Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer's Disease. Scientific Reports. 9: 1311. PMID 30718609 DOI: 10.1038/S41598-018-37151-Z |
0.382 |
|
2019 |
Trujillo-Estrada L, Kuang RR, Da Cunha C, Forner S, Martini AC, Nguyen C, Baglietto-Vargas D, LaFerla F. P4-522: TYPE 2 DIABETES MELLITUS INDUCES TAU-INDEPENDENT COGNITIVE AND SYNAPTIC DEFICITS IN A MOUSE MODEL Alzheimer's & Dementia. 15: P1514-P1514. DOI: 10.1016/J.Jalz.2019.08.069 |
0.327 |
|
2019 |
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Jiang S, Kramár E, Nuñez-Diaz C, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Soto C, Gutierrez A, Moreno-Gonzalez I, ... ... LaFerla F, et al. P3-069: HUMAN WILD TYPE Aβ KNOCK-IN MICE AS A BASIS TO STUDY SPORADIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P953-P953. DOI: 10.1016/J.Jalz.2019.06.3096 |
0.491 |
|
2018 |
Frontiñan-Rubio J, Sancho-Bielsa FJ, Peinado JR, LaFerla FM, Giménez-Llort L, Durán-Prado M, Alcain FJ. Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease. Molecular and Cellular Neurosciences. PMID 29953929 DOI: 10.1016/j.mcn.2018.06.005 |
0.446 |
|
2018 |
Baglietto-Vargas D, Prieto GA, Limon A, Forner S, Rodriguez-Ortiz CJ, Ikemura K, Ager RR, Medeiros R, Trujillo-Estrada L, Martini AC, Kitazawa M, Davila JC, Cotman CW, Gutierrez A, LaFerla FM. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. e12791. PMID 29877034 DOI: 10.1111/Acel.12791 |
0.552 |
|
2018 |
Lee S, Choi BR, Kim J, LaFerla FM, Park JHY, Han JS, Lee KW, Kim J. Sulforaphane Upregulates the Heat Shock Protein Co-Chaperone CHIP and Clears Amyloid-β and Tau in a Mouse Model of Alzheimer's Disease. Molecular Nutrition & Food Research. e1800240. PMID 29714053 DOI: 10.1002/mnfr.201800240 |
0.403 |
|
2018 |
Van der Jeugd A, Parra-Damas A, Baeta-Corral R, Soto-Faguás CM, Ahmed T, LaFerla FM, Giménez-Llort L, D'Hooge R, Saura CA. Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice. Scientific Reports. 8: 6431. PMID 29691439 DOI: 10.1038/S41598-018-24741-0 |
0.45 |
|
2018 |
Martini AC, Forner S, Trujillo-Estrada L, Baglietto-Vargas D, LaFerla FM. Past to Future: What Animal Models Have Taught Us About Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29504540 DOI: 10.3233/JAD-179917 |
0.401 |
|
2018 |
Sosna J, Philipp S, Albay R, Reyes-Ruiz JM, Baglietto-Vargas D, LaFerla FM, Glabe CG. Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease. Molecular Neurodegeneration. 13: 11. PMID 29490706 DOI: 10.1186/s13024-018-0244-x |
0.473 |
|
2017 |
Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y. Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Scientific Reports. 7: 17762. PMID 29259249 DOI: 10.1038/s41598-017-17999-3 |
0.36 |
|
2017 |
Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y. Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Scientific Reports. 7: 17762. PMID 29259249 DOI: 10.1038/s41598-017-17999-3 |
0.36 |
|
2017 |
Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y. Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Scientific Reports. 7: 17762. PMID 29259249 DOI: 10.1038/s41598-017-17999-3 |
0.36 |
|
2017 |
Reidling JC, Relaño-Ginés A, Holley SM, Ochaba J, Moore C, Fury B, Lau A, Tran AH, Yeung S, Salamati D, Zhu C, Hatami A, Cepeda C, Barry JA, Kamdjou T, ... ... LaFerla FM, et al. Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. Stem Cell Reports. PMID 29233555 DOI: 10.1016/J.Stemcr.2017.11.005 |
0.622 |
|
2017 |
Forner S, Baglietto-Vargas D, Martini AC, Trujillo-Estrada L, LaFerla FM. Synaptic Impairment in Alzheimer's Disease: A Dysregulated Symphony. Trends in Neurosciences. PMID 28494972 DOI: 10.1016/j.tins.2017.04.002 |
0.447 |
|
2017 |
Baglietto-Vargas D, Cai L, Forner S, Martini A, Cunha C, Trujillo-Estrada L, LaFerla F. [P1-107]: APPKI-HaβWT: A NOVEL TRANSGENIC MOUSE TO MODEL SPORADIC ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P281-P281. DOI: 10.1016/J.Jalz.2017.06.174 |
0.451 |
|
2016 |
Oka S, Leon J, Sakumi K, Ide T, Kang D, LaFerla FM, Nakabeppu Y. Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease. Scientific Reports. 6: 37889. PMID 27897204 DOI: 10.1038/srep37889 |
0.386 |
|
2016 |
Manuel I, Lombardero L, Laferla FM, Giménez-Llort L, Rodríguez-Puertas R. Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease. Neuroscience. PMID 27223629 DOI: 10.1016/j.neuroscience.2016.05.012 |
0.389 |
|
2016 |
Baglietto-Vargas D, Shi J, Yaeger DM, Ager R, LaFerla FM. Diabetes and Alzheimer's Disease Crosstalk. Neuroscience and Biobehavioral Reviews. PMID 26969101 DOI: 10.1016/J.Neubiorev.2016.03.005 |
0.321 |
|
2015 |
Fisher A, Bezprozvanny I, Wu L, Ryskamp DA, Bar-Ner N, Natan N, Brandeis R, Elkon H, Nahum V, Gershonov E, LaFerla FM, Medeiros R. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer's Disease. Neuro-Degenerative Diseases. PMID 26606130 DOI: 10.1159/000440864 |
0.309 |
|
2015 |
Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, LaFerla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-87. PMID 26305968 DOI: 10.1073/Pnas.1514486112 |
0.331 |
|
2015 |
Yeung ST, Martinez-Coria H, Ager RR, Rodriguez-Ortiz CJ, Baglietto-Vargas D, LaFerla FM. Repeated cognitive stimulation alleviates memory impairments in an Alzheimer's disease mouse model. Brain Research Bulletin. 117: 10-5. PMID 26162480 DOI: 10.1016/J.Brainresbull.2015.07.001 |
0.714 |
|
2015 |
Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green KN, Baram TZ, LaFerla FM. Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice. Journal of Neurochemistry. PMID 26077803 DOI: 10.1111/Jnc.13195 |
0.843 |
|
2015 |
Clarke JR, Lyra E Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazão R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, ... ... LaFerla FM, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. Embo Molecular Medicine. 7: 190-210. PMID 25617315 DOI: 10.15252/Emmm.201404183 |
0.384 |
|
2015 |
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... LaFerla FM, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157 |
0.367 |
|
2015 |
Ager RR, Davis JL, Agazaryan A, Benavente F, Poon WW, LaFerla FM, Blurton-Jones M. Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss. Hippocampus. 25: 813-26. PMID 25530343 DOI: 10.1002/Hipo.22405 |
0.718 |
|
2015 |
Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, Laferla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-E5087. DOI: 10.1073/pnas.1514486112 |
0.304 |
|
2014 |
Garin D, Virgone-Carlotta A, Gözel B, Oukhatar F, Perret P, Marti-Battle D, Touret M, Millet P, Dubois-Dauphin M, Meyronet D, Streichenberger N, Laferla FM, Demeunynck M, Chierici S, Sallanon MM, et al. COB231 targets amyloid plaques in post-mortem human brain tissue and in an Alzheimer mouse model. Journal of Neurochemistry. PMID 25258048 DOI: 10.1111/jnc.12951 |
0.436 |
|
2014 |
Hascalovici JR, Song W, Liberman A, Vaya J, Khatib S, Holcroft C, Laferla F, Schipper HM. Neural HO-1/sterol interactions in vivo: implications for Alzheimer's disease. Neuroscience. 280: 40-9. PMID 25218961 DOI: 10.1016/J.Neuroscience.2014.09.001 |
0.453 |
|
2014 |
Myczek K, Yeung ST, Castello N, Baglietto-Vargas D, LaFerla FM. Hippocampal adaptive response following extensive neuronal loss in an inducible transgenic mouse model. Plos One. 9: e106009. PMID 25184527 DOI: 10.1371/Journal.Pone.0106009 |
0.792 |
|
2014 |
Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. Optical imaging in an Alzheimer's mouse model reveals amyloid-β-dependent vascular impairment. Neurophotonics. 1: 011005. PMID 25133200 DOI: 10.1117/1.Nph.1.1.011005 |
0.819 |
|
2014 |
Kazim SF, Blanchard J, Dai CL, Tung YC, LaFerla FM, Iqbal IG, Iqbal K. Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 71: 110-30. PMID 25046994 DOI: 10.1016/J.Nbd.2014.07.001 |
0.505 |
|
2014 |
Rodriguez-Ortiz CJ, Baglietto-Vargas D, Martinez-Coria H, LaFerla FM, Kitazawa M. Upregulation of miR-181 decreases c-Fos and SIRT-1 in the hippocampus of 3xTg-AD mice. Journal of Alzheimer's Disease : Jad. 42: 1229-38. PMID 25024332 DOI: 10.3233/Jad-140204 |
0.357 |
|
2014 |
Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Research & Therapy. 5: 46. PMID 25022790 DOI: 10.1186/Scrt440 |
0.85 |
|
2014 |
Walls KC, Ager RR, Vasilevko V, Cheng D, Medeiros R, LaFerla FM. p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice. Neuroscience Letters. 575: 96-100. PMID 24887583 DOI: 10.1016/J.Neulet.2014.05.047 |
0.473 |
|
2014 |
Castello NA, Nguyen MH, Tran JD, Cheng D, Green KN, LaFerla FM. 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss. Plos One. 9: e91453. PMID 24614170 DOI: 10.1371/Journal.Pone.0091453 |
0.829 |
|
2014 |
Bedse G, Romano A, Cianci S, Lavecchia AM, Lorenzo P, Elphick MR, Laferla FM, Vendemiale G, Grillo C, Altieri F, Cassano T, Gaetani S. Altered expression of the CB1 cannabinoid receptor in the triple transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 40: 701-12. PMID 24496074 DOI: 10.3233/JAD-131910 |
0.44 |
|
2014 |
Chabrier MA, Cheng D, Castello NA, Green KN, LaFerla FM. Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease. Neurobiology of Disease. 64: 107-17. PMID 24440055 DOI: 10.1016/J.Nbd.2014.01.007 |
0.842 |
|
2014 |
Abbondante S, Baglietto-Vargas D, Rodriguez-Ortiz CJ, Estrada-Hernandez T, Medeiros R, Laferla FM. Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes. The American Journal of Pathology. 184: 819-26. PMID 24412516 DOI: 10.1016/j.ajpath.2013.11.021 |
0.372 |
|
2014 |
Yeung ST, Myczek K, Kang AP, Chabrier MA, Baglietto-Vargas D, Laferla FM. Impact of hippocampal neuronal ablation on neurogenesis and cognition in the aged brain. Neuroscience. 259: 214-22. PMID 24316470 DOI: 10.1016/J.Neuroscience.2013.11.054 |
0.808 |
|
2014 |
Lin AJ, Castello NA, Lee G, Green KN, Durkin AJ, Choi B, LaFerla F, Tromberg BJ. In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease. Lasers in Surgery and Medicine. 46: 27-33. PMID 24284732 DOI: 10.1002/Lsm.22206 |
0.831 |
|
2014 |
Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM. α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. The American Journal of Pathology. 184: 520-9. PMID 24269557 DOI: 10.1016/J.Ajpath.2013.10.010 |
0.851 |
|
2014 |
Baglietto-Vargas D, Kitazawa M, Le EJ, Estrada-Hernandez T, Rodriguez-Ortiz CJ, Medeiros R, Green KN, LaFerla FM. Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiology of Disease. 62: 407-15. PMID 24176788 DOI: 10.1016/J.Nbd.2013.10.019 |
0.652 |
|
2014 |
Hokama M, Oka S, Leon J, Ninomiya T, Honda H, Sasaki K, Iwaki T, Ohara T, Sasaki T, LaFerla FM, Kiyohara Y, Nakabeppu Y. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study. Cerebral Cortex (New York, N.Y. : 1991). 24: 2476-88. PMID 23595620 DOI: 10.1093/cercor/bht101 |
0.362 |
|
2014 |
Fisher A, Medeiros R, Bar-Ner N, Natan N, Brandeis R, Elkon H, Nahum V, Grigoryan G, Segal M, Laferla F. A novel multipotent sigma 1/M1 muscarinic activator for a comprehensive therapeutic strategy in Alzheimer's disease Neurobiology of Aging. 35. DOI: 10.1016/J.Neurobiolaging.2014.01.052 |
0.369 |
|
2014 |
Fisher A, Medeiros R, Barner N, Natan N, Brandeis R, Elkon H, Nahum V, Grigoryan G, Segal M, LaFerla F. M1 MUSCARINIC AGONISTS AND A MULTIPOTENT ACTIVATOR OF SIGMA1/M1 MUSCARINIC RECEPTORS: FUTURE THERAPEUTICS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P123-P123. DOI: 10.1016/J.Jalz.2014.04.039 |
0.306 |
|
2013 |
Rodriguez-Ortiz CJ, Hoshino H, Cheng D, Liu-Yescevitz L, Blurton-Jones M, Wolozin B, LaFerla FM, Kitazawa M. Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. The American Journal of Pathology. 183: 504-15. PMID 23747512 DOI: 10.1016/J.Ajpath.2013.04.014 |
0.664 |
|
2013 |
Rasool S, Martinez-Coria H, Wu JW, LaFerla F, Glabe CG. Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice. Journal of Neurochemistry. 126: 473-82. PMID 23672786 DOI: 10.1111/Jnc.12305 |
0.538 |
|
2013 |
Medeiros R, Kitazawa M, Passos GF, Baglietto-Vargas D, Cheng D, Cribbs DH, LaFerla FM. Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice. The American Journal of Pathology. 182: 1780-9. PMID 23506847 DOI: 10.1016/J.Ajpath.2013.01.051 |
0.363 |
|
2013 |
Ghosh S, Wu MD, Shaftel SS, Kyrkanides S, LaFerla FM, Olschowka JA, O'Banion MK. Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5053-64. PMID 23486975 DOI: 10.1523/Jneurosci.4361-12.2013 |
0.379 |
|
2013 |
Passos GF, Medeiros R, Cheng D, Vasilevko V, Laferla FM, Cribbs DH. The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice. The American Journal of Pathology. 182: 1740-9. PMID 23470163 DOI: 10.1016/j.ajpath.2013.01.021 |
0.484 |
|
2013 |
Baglietto-Vargas D, Medeiros R, Martinez-Coria H, LaFerla FM, Green KN. Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. Biological Psychiatry. 74: 357-66. PMID 23312564 DOI: 10.1016/j.biopsych.2012.12.003 |
0.632 |
|
2013 |
Medeiros R, LaFerla FM. Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony. Experimental Neurology. 239: 133-8. PMID 23063604 DOI: 10.1016/j.expneurol.2012.10.007 |
0.367 |
|
2013 |
Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, ... ... Laferla F, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003 |
0.337 |
|
2013 |
Solé-Domènech S, Sjövall P, Vukojević V, Fernando R, Codita A, Salve S, Bogdanović N, Mohammed AH, Hammarström P, Nilsson KP, LaFerla FM, Jacob S, Berggren PO, Giménez-Llort L, Schalling M, et al. Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging. Acta Neuropathologica. 125: 145-57. PMID 22996963 DOI: 10.1007/S00401-012-1046-9 |
0.314 |
|
2013 |
Soejima N, Ohyagi Y, Nakamura N, Himeno E, Iinuma KM, Sakae N, Yamasaki R, Tabira T, Murakami K, Irie K, Kinoshita N, LaFerla FM, Kiyohara Y, Iwaki T, Kira J. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease. Current Alzheimer Research. 10: 11-20. PMID 22950910 |
0.463 |
|
2013 |
Medeiros R, Chabrier MA, LaFerla FM. Elucidating the triggers, progression, and effects of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: S195-210. PMID 22635105 DOI: 10.3233/JAD-2012-129009 |
0.842 |
|
2013 |
Walker MP, LaFerla FM, Oddo SS, Brewer GJ. Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer's disease. Age (Dordrecht, Netherlands). 35: 519-31. PMID 22237558 DOI: 10.1007/s11357-011-9375-5 |
0.612 |
|
2012 |
Chen Y, Tian Z, Liang Z, Sun S, Dai CL, Lee MH, LaFerla FM, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX. Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease. Plos One. 7: e51432. PMID 23236499 DOI: 10.1371/Journal.Pone.0051432 |
0.431 |
|
2012 |
Chabrier MA, Blurton-Jones M, Agazaryan AA, Nerhus JL, Martinez-Coria H, LaFerla FM. Soluble aβ promotes wild-type tau pathology in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17345-50. PMID 23197725 DOI: 10.1523/Jneurosci.0172-12.2012 |
0.853 |
|
2012 |
Yan XX, Cai Y, Shelton J, Deng SH, Luo XG, Oddo S, Laferla FM, Cai H, Rose GM, Patrylo PR. Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice. Plos One. 7: e48782. PMID 23155407 DOI: 10.1371/Journal.Pone.0048782 |
0.666 |
|
2012 |
Neely Kayala KM, Dickinson GD, Minassian A, Walls KC, Green KN, Laferla FM. Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function. Brain Research. 1489: 8-16. PMID 23103503 DOI: 10.1016/j.brainres.2012.10.036 |
0.387 |
|
2012 |
LaFerla FM, Green KN. Animal models of Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2. PMID 23002015 DOI: 10.1101/cshperspect.a006320 |
0.502 |
|
2012 |
Chakravarthy B, Gaudet C, Ménard M, Brown L, Atkinson T, Laferla FM, Ito S, Armato U, Dal Prà I, Whitfield J. Reduction of the immunostainable length of the hippocampal dentate granule cells' primary cilia in 3xAD-transgenic mice producing human Aβ(1-42) and tau. Biochemical and Biophysical Research Communications. 427: 218-22. PMID 22995307 DOI: 10.1016/j.bbrc.2012.09.056 |
0.414 |
|
2012 |
Guzmán-Ramos K, Moreno-Castilla P, Castro-Cruz M, McGaugh JL, MartÃnez-Coria H, LaFerla FM, Bermúdez-Rattoni F. Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 453-60. PMID 22984283 DOI: 10.1101/Lm.026070.112 |
0.35 |
|
2012 |
Koike MA, Lin AJ, Pham J, Nguyen E, Yeh JJ, Rahimian R, Tromberg BJ, Choi B, Green KN, LaFerla FM. APP knockout mice experience acute mortality as the result of ischemia. Plos One. 7: e42665. PMID 22912719 DOI: 10.1371/Journal.Pone.0042665 |
0.78 |
|
2012 |
Castello NA, Green KN, LaFerla FM. Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology. Plos One. 7: e39566. PMID 22870188 DOI: 10.1371/Journal.Pone.0039566 |
0.837 |
|
2012 |
Rasool S, Albay R, Martinez-Coria H, Breydo L, Wu J, Milton S, Misra S, Tran A, Pensalfini A, Laferla F, Kayed R, Glabe CG. Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice. Molecular Neurodegeneration. 7: 37. PMID 22866920 DOI: 10.1186/1750-1326-7-37 |
0.35 |
|
2012 |
Wolf AB, Braden BB, Bimonte-Nelson H, Kusne Y, Young N, Engler-Chiurazzi E, Garcia AN, Walker DG, Moses GS, Tran H, LaFerla F, Lue L, Emerson Lombardo N, Valla J. Broad-based nutritional supplementation in 3xTg mice corrects mitochondrial function and indicates sex-specificity in response to Alzheimer's disease intervention. Journal of Alzheimer's Disease : Jad. 32: 217-32. PMID 22796872 DOI: 10.3233/Jad-2012-120478 |
0.442 |
|
2012 |
Girão da Cruz MT, Jordão J, Dasilva KA, Ayala-Grosso CA, Ypsilanti A, Weng YQ, Laferla FM, McLaurin J, Aubert I. Early increases in soluble amyloid-β levels coincide with cholinergic degeneration in 3xTg-AD mice. Journal of Alzheimer's Disease : Jad. 32: 267-72. PMID 22776965 DOI: 10.3233/Jad-2012-100732 |
0.463 |
|
2012 |
Walls KC, Coskun P, Gallegos-Perez JL, Zadourian N, Freude K, Rasool S, Blurton-Jones M, Green KN, LaFerla FM. Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid. The Journal of Biological Chemistry. 287: 30317-27. PMID 22753410 DOI: 10.1074/Jbc.M112.365890 |
0.739 |
|
2012 |
Medeiros R, Kitazawa M, Chabrier MA, Cheng D, Baglietto-Vargas D, Kling A, Moeller A, Green KN, LaFerla FM. Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice. The American Journal of Pathology. 181: 616-25. PMID 22688056 DOI: 10.1016/J.Ajpath.2012.04.020 |
0.851 |
|
2012 |
Takamura A, Sato Y, Watabe D, Okamoto Y, Nakata T, Kawarabayashi T, Oddo S, Laferla FM, Shoji M, Matsubara E. Sortilin is required for toxic action of Aβ oligomers (AβOs): extracellular AβOs trigger apoptosis, and intraneuronal AβOs impair degradation pathways. Life Sciences. 91: 1177-86. PMID 22579764 DOI: 10.1016/J.Lfs.2012.04.038 |
0.631 |
|
2012 |
Kitazawa M, Medeiros R, Laferla FM. Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions. Current Pharmaceutical Design. 18: 1131-47. PMID 22288400 DOI: 10.2174/138161212799315786 |
0.407 |
|
2012 |
Coskun P, Wyrembak J, Schriner SE, Chen HW, Marciniack C, Laferla F, Wallace DC. A mitochondrial etiology of Alzheimer and Parkinson disease. Biochimica Et Biophysica Acta. 1820: 553-64. PMID 21871538 DOI: 10.1016/J.Bbagen.2011.08.008 |
0.383 |
|
2012 |
Cai Y, Zhang XM, Macklin LN, Cai H, Luo XG, Oddo S, Laferla FM, Struble RG, Rose GM, Patrylo PR, Yan XX. BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology. Neurotoxicity Research. 21: 160-74. PMID 21725719 DOI: 10.1007/S12640-011-9256-9 |
0.593 |
|
2012 |
Blurton-Jones M, Ager R, Nerhus J, Agazaryan A, Huhn S, Capela A, LaFerla F. P3-345: Restoration of memory in mouse models of Alzheimer's disease and neuronal loss: A new paradigm using human neural stem cell therapy Alzheimer's & Dementia. 8: P577-P578. DOI: 10.1016/J.Jalz.2012.05.1569 |
0.656 |
|
2012 |
Chabrier M, Blurton-Jones M, Agazaryan A, Nerhus J, LaFerla F, Coria HM. Soluble Aβ promotes wild-type tau pathology in vivo Alzheimers & Dementia. 8: 475. DOI: 10.1016/J.Jalz.2012.05.1279 |
0.826 |
|
2012 |
Castello N, Green K, LaFerla F. P3-037: Impact of genetic knockdown of brain-derived neurotrophic factor in 3xTg Alzheimer's mice Alzheimer's & Dementia. 8: P468-P468. DOI: 10.1016/J.Jalz.2012.05.1255 |
0.812 |
|
2012 |
Baglietto-Vargas D, Coria HM, Rodriguez-Ortiz C, Green K, Medeiros R, Kitazawa M, LaFerla F. P3-006: Endogenous tau contributes to Alzheimer's-like tau pathology in 3xTg mice Alzheimer's & Dementia. 8: P458-P458. DOI: 10.1016/J.Jalz.2012.05.1224 |
0.639 |
|
2012 |
Ager R, Blurton-Jones M, Davis J, Agazaryan A, LaFerla F. P2-391: Human neural stem cell transplantation results in memory improvement in a 3xTg Alzheimer's disease model mice Alzheimer's & Dementia. 8: P399-P400. DOI: 10.1016/J.Jalz.2012.05.1101 |
0.665 |
|
2012 |
Blurton-Jones M, Nerhus JL, LaFerla FM. Transplanting Stem Cells into the Brain Human Stem Cell Manual. 529-542. DOI: 10.1016/B978-0-12-385473-5.00034-5 |
0.546 |
|
2011 |
Kitazawa M, Cheng D, Tsukamoto MR, Koike MA, Wes PD, Vasilevko V, Cribbs DH, LaFerla FM. Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model. Journal of Immunology (Baltimore, Md. : 1950). 187: 6539-49. PMID 22095718 DOI: 10.4049/Jimmunol.1100620 |
0.785 |
|
2011 |
Alonso E, Vale C, Vieytes MR, Laferla FM, Giménez-Llort L, Botana LM. 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular Aβ and hyperphosphorylated tau in vitro. Neurochemistry International. 59: 1056-65. PMID 21907746 DOI: 10.1016/j.neuint.2011.08.013 |
0.346 |
|
2011 |
Bianchi FT, Camera P, Ala U, Imperiale D, Migheli A, Boda E, Tempia F, Berto G, Bosio Y, Oddo S, LaFerla FM, Taraglio S, Dotti CG, Di Cunto F. The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides. Plos One. 6: e22370. PMID 21829458 DOI: 10.1371/Journal.Pone.0022370 |
0.639 |
|
2011 |
Tang JX, Mardini F, Caltagarone BM, Garrity ST, Li RQ, Bianchi SL, Gomes O, Laferla FM, Eckenhoff RG, Eckenhoff MF. Anesthesia in presymptomatic Alzheimer's disease: a study using the triple-transgenic mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 521-531.e1. PMID 21745760 DOI: 10.1016/J.Jalz.2010.10.003 |
0.392 |
|
2011 |
Tran HT, LaFerla FM, Holtzman DM, Brody DL. Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9513-25. PMID 21715616 DOI: 10.1523/Jneurosci.0858-11.2011 |
0.433 |
|
2011 |
Medeiros R, Kitazawa M, Caccamo A, Baglietto-Vargas D, Estrada-Hernandez T, Cribbs DH, Fisher A, LaFerla FM. Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline. The American Journal of Pathology. 179: 980-91. PMID 21704011 DOI: 10.1016/J.Ajpath.2011.04.041 |
0.415 |
|
2011 |
Alonso E, Vale C, Vieytes MR, Laferla FM, Giménez-Llort L, Botana LM. The cholinergic antagonist gymnodimine improves Aβ and tau neuropathology in an in vitro model of Alzheimer disease. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 27: 783-94. PMID 21691095 DOI: 10.1159/000330086 |
0.345 |
|
2011 |
Freude KK, Penjwini M, Davis JL, LaFerla FM, Blurton-Jones M. Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells. The Journal of Biological Chemistry. 286: 24264-74. PMID 21606494 DOI: 10.1074/Jbc.M111.227421 |
0.616 |
|
2011 |
Sy M, Kitazawa M, Medeiros R, Whitman L, Cheng D, Lane TE, Laferla FM. Inflammation induced by infection potentiates tau pathological features in transgenic mice. The American Journal of Pathology. 178: 2811-22. PMID 21531375 DOI: 10.1016/J.Ajpath.2011.02.012 |
0.655 |
|
2011 |
Garin D, Oukhatar F, Mahon AB, Try AC, Dubois-Dauphin M, Laferla FM, Demeunynck M, Sallanon MM, Chierici S. Proflavine derivatives as fluorescent imaging agents of amyloid deposits. Bioorganic & Medicinal Chemistry Letters. 21: 2203-6. PMID 21435875 DOI: 10.1016/j.bmcl.2011.03.010 |
0.369 |
|
2011 |
Koike MA, Garcia FG, Kitazawa M, Green KN, Laferla FM. Long term changes in phospho-APP and tau aggregation in the 3xTg-AD mice following cerebral ischemia. Neuroscience Letters. 495: 55-9. PMID 21419194 DOI: 10.1016/J.Neulet.2011.03.034 |
0.829 |
|
2011 |
Green KN, Khashwji H, Estrada T, Laferla FM. ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo. Annals of Neurology. 69: 831-44. PMID 21416488 DOI: 10.1002/ana.22325 |
0.568 |
|
2011 |
Neely KM, Green KN, LaFerla FM. Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2781-91. PMID 21414900 DOI: 10.1523/JNEUROSCI.5156-10.2010 |
0.718 |
|
2011 |
Himeno E, Ohyagi Y, Ma L, Nakamura N, Miyoshi K, Sakae N, Motomura K, Soejima N, Yamasaki R, Hashimoto T, Tabira T, LaFerla FM, Kira J. Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation. Annals of Neurology. 69: 248-56. PMID 21387370 DOI: 10.1002/ana.22319 |
0.433 |
|
2011 |
Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ. Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease. Annals of Biomedical Engineering. 39: 1349-57. PMID 21331663 DOI: 10.1007/S10439-011-0269-6 |
0.785 |
|
2011 |
García-Mesa Y, López-Ramos JC, Giménez-Llort L, Revilla S, Guerra R, Gruart A, Laferla FM, Cristòfol R, Delgado-García JM, Sanfeliu C. Physical exercise protects against Alzheimer's disease in 3xTg-AD mice. Journal of Alzheimer's Disease : Jad. 24: 421-54. PMID 21297257 DOI: 10.3233/Jad-2011-101635 |
0.383 |
|
2011 |
Chou JL, Shenoy DV, Thomas N, Choudhary PK, Laferla FM, Goodman SR, Breen GA. Early dysregulation of the mitochondrial proteome in a mouse model of Alzheimer's disease. Journal of Proteomics. 74: 466-79. PMID 21237293 DOI: 10.1016/J.Jprot.2010.12.012 |
0.37 |
|
2011 |
Medeiros R, Baglietto-Vargas D, LaFerla FM. The role of tau in Alzheimer's disease and related disorders. Cns Neuroscience & Therapeutics. 17: 514-24. PMID 20553310 DOI: 10.1111/j.1755-5949.2010.00177.x |
0.416 |
|
2011 |
Lopes JP, Blurton-Jones M, Yamasaki TR, Agostinho P, LaFerla FM. Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not aß and tau pathology Advances in Alzheimer's Disease. 1: 139-148. DOI: 10.3233/978-1-60750-733-8-139 |
0.815 |
|
2011 |
Solé-Domènech S, Sjövall P, Vukojevic V, Codita A, Salve S, Schalling M, LaFerla F, Giménez-Llort L, Nilsson P, Hammarström P, Terenius L, Johansson B. Cholesterol accumulates in the vicinity of amyloid-beta deposits in brain tissue Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2093 |
0.352 |
|
2011 |
O'Neill C, LaFerla F, Coakley M. P3-211: Hyperactivation of PI3-kinase-Akt signaling: a central molecular link between early Amuloid beta and tau pathogenesis in Alzheimer's disease Alzheimer's & Dementia. 7: S583-S584. DOI: 10.1016/J.Jalz.2011.05.1652 |
0.399 |
|
2011 |
Fisher R, Gannon K, Krishnan R, Tsubery H, Masliah E, Rockenstein E, Kirschner D, Inouye H, Myszka D, Cirrito J, Green K, Wright J, Solomon J, LaFerla F, Solomon B. NPT001: A candidate therapeutic for clearance of beta-amyloid and tau aggregates in Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1328 |
0.621 |
|
2011 |
Sy M, Kitazawa M, Laferla F. The 3xTg-AD mouse model: Reproducing and modulating plaque and tangle pathology Neuromethods. 48: 469-482. DOI: 10.1007/978-1-60761-898-0_24 |
0.657 |
|
2010 |
Casadesus G, Arendash G, Laferla F, McDonald M. Animal models of Alzheimer's disease. International Journal of Alzheimer's Disease. 2010: 606357. PMID 21804934 DOI: 10.4061/2010/606357 |
0.531 |
|
2010 |
Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. Plos One. 5: e15477. PMID 21103384 DOI: 10.1371/Journal.Pone.0015477 |
0.426 |
|
2010 |
Parachikova A, Green KN, Hendrix C, LaFerla FM. Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease. Plos One. 5: e14015. PMID 21103342 DOI: 10.1371/Journal.Pone.0014015 |
0.551 |
|
2010 |
Piedrahita D, Hernández I, López-Tobón A, Fedorov D, Obara B, Manjunath BS, Boudreau RL, Davidson B, Laferla F, Gallego-Gómez JC, Kosik KS, Cardona-Gómez GP. Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13966-76. PMID 20962218 DOI: 10.1523/Jneurosci.3637-10.2010 |
0.459 |
|
2010 |
Blanchard J, Wanka L, Tung YC, Cárdenas-Aguayo Mdel C, LaFerla FM, Iqbal K, Grundke-Iqbal I. Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice. Acta Neuropathologica. 120: 605-21. PMID 20697724 DOI: 10.1007/S00401-010-0734-6 |
0.471 |
|
2010 |
Nicholson RM, Kusne Y, Nowak LA, LaFerla FM, Reiman EM, Valla J. Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models. Brain Research. 1347: 179-85. PMID 20677372 DOI: 10.1016/J.Brainres.2010.05.084 |
0.416 |
|
2010 |
LaFerla FM. Pathways linking Abeta and tau pathologies. Biochemical Society Transactions. 38: 993-5. PMID 20658991 DOI: 10.1042/BST0380993 |
0.417 |
|
2010 |
Sterniczuk R, Antle MC, Laferla FM, Dyck RH. Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 2. Behavioral and cognitive changes. Brain Research. 1348: 149-55. PMID 20558146 DOI: 10.1016/J.Brainres.2010.06.011 |
0.442 |
|
2010 |
Parachikova A, Vasilevko V, Cribbs DH, LaFerla FM, Green KN. Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation. Journal of Alzheimer's Disease : Jad. 21: 527-42. PMID 20555131 DOI: 10.3233/Jad-2010-100204 |
0.618 |
|
2010 |
Clinton LK, Blurton-Jones M, Myczek K, Trojanowski JQ, LaFerla FM. Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7281-9. PMID 20505094 DOI: 10.1523/Jneurosci.0490-10.2010 |
0.836 |
|
2010 |
Koike MA, Green KN, Blurton-Jones M, Laferla FM. Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. The American Journal of Pathology. 177: 300-10. PMID 20472896 DOI: 10.2353/Ajpath.2010.090750 |
0.848 |
|
2010 |
Sterniczuk R, Dyck RH, Laferla FM, Antle MC. Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1. Circadian changes. Brain Research. 1348: 139-48. PMID 20471965 DOI: 10.1016/J.Brainres.2010.05.013 |
0.444 |
|
2010 |
Fuhrmann M, Bittner T, Jung CK, Burgold S, Page RM, Mitteregger G, Haass C, LaFerla FM, Kretzschmar H, Herms J. Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nature Neuroscience. 13: 411-3. PMID 20305648 DOI: 10.1038/Nn.2511 |
0.331 |
|
2010 |
Chakravarthy B, Gaudet C, Ménard M, Atkinson T, Brown L, Laferla FM, Armato U, Whitfield J. Amyloid-beta peptides stimulate the expression of the p75(NTR) neurotrophin receptor in SHSY5Y human neuroblastoma cells and AD transgenic mice. Journal of Alzheimer's Disease : Jad. 19: 915-25. PMID 20157247 DOI: 10.3233/JAD-2010-1288 |
0.437 |
|
2010 |
Bryleva EY, Rogers MA, Chang CC, Buen F, Harris BT, Rousselet E, Seidah NG, Oddo S, LaFerla FM, Spencer TA, Hickey WF, Chang TY. ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proceedings of the National Academy of Sciences of the United States of America. 107: 3081-6. PMID 20133765 DOI: 10.1073/Pnas.0913828107 |
0.665 |
|
2010 |
Querfurth HW, LaFerla FM. Alzheimer's disease. The New England Journal of Medicine. 362: 329-44. PMID 20107219 DOI: 10.1056/NEJMra0909142 |
0.305 |
|
2010 |
Hasegawa T, Mikoda N, Kitazawa M, LaFerla FM. Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice. Plos One. 5: e8593. PMID 20098691 DOI: 10.1371/Journal.Pone.0008593 |
0.46 |
|
2010 |
Martinez-Coria H, Green KN, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM. Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. The American Journal of Pathology. 176: 870-80. PMID 20042680 DOI: 10.2353/Ajpath.2010.090452 |
0.653 |
|
2010 |
Vale C, Alonso E, Rubiolo JA, Vieytes MR, LaFerla FM, Giménez-Llort L, Botana LM. Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice. Cellular and Molecular Neurobiology. 30: 577-90. PMID 19943189 DOI: 10.1007/s10571-009-9482-3 |
0.477 |
|
2010 |
Bianchi SL, Caltagarone BM, Laferla FM, Eckenhoff RG, Kelz MB. Inhaled anesthetic potency in aged Alzheimer mice. Anesthesia and Analgesia. 110: 427-30. PMID 19820240 DOI: 10.1213/Ane.0B013E3181B5A292 |
0.396 |
|
2010 |
España J, Giménez-Llort L, Valero J, Miñano A, Rábano A, Rodriguez-Alvarez J, LaFerla FM, Saura CA. Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice. Biological Psychiatry. 67: 513-21. PMID 19664757 DOI: 10.1016/j.biopsych.2009.06.015 |
0.46 |
|
2010 |
Nakashima AS, Oddo S, Laferla FM, Dyck RH. Experience-dependent regulation of vesicular zinc in male and female 3xTg-AD mice. Neurobiology of Aging. 31: 605-13. PMID 18603329 DOI: 10.1016/J.Neurobiolaging.2008.05.028 |
0.627 |
|
2010 |
Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Muller F, Loring JF, Poon WW, Green K, LaFerla FM. O1-04-01: Using neural stem cells to promote plasticity and improve cognition in transgenic AD mice Alzheimer's & Dementia. 6: S76-S76. DOI: 10.1016/J.Jalz.2010.05.225 |
0.817 |
|
2010 |
Vargas DB, Green KN, Medeiros R, Martinez-Coria H, LaFerla FM. P3-384: Disease modifying effects of mifepristone (RU-486) in the 3xTg-AD mouse model of Alzheimer's disease Alzheimer's & Dementia. 6: S565-S565. DOI: 10.1016/j.jalz.2010.05.1926 |
0.577 |
|
2010 |
Green KN, Kitazawa M, Dagher NN, Koike M, Rezvani R, West BL, LaFerla FM. P3-367: Reductions in LPS- and Alzheimer's disease neuropathology-induced CNS inflammation with selective colony stimulating factor-1 receptor kinase inhibitors Alzheimer's & Dementia. 6: S559-S560. DOI: 10.1016/J.Jalz.2010.05.1909 |
0.758 |
|
2010 |
Rogers M, Bryleva E, Chang C, Buen F, Harris B, Rousselet E, Seidah N, Oddo S, LaFerla F, Spencer T, Hickey W, Chang TY. P3-285: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice Alzheimer's & Dementia. 6: S535-S535. DOI: 10.1016/J.Jalz.2010.05.1785 |
0.674 |
|
2010 |
Neely KM, Green KN, LaFerla FM. P2-274: Presenilins are necessary for efficient autophagic and lysosomal functioning through a gamma-secretase-independent mechanism Alzheimer's & Dementia. 6: S394-S394. DOI: 10.1016/j.jalz.2010.05.1324 |
0.617 |
|
2009 |
Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, ... ... LaFerla FM, et al. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of Cell Biology. 187: 1083-99. PMID 20026656 DOI: 10.1083/Jcb.200909067 |
0.473 |
|
2009 |
Aiken CT, Steffan JS, Guerrero CM, Khashwji H, Lukacsovich T, Simmons D, Purcell JM, Menhaji K, Zhu YZ, Green K, Laferla F, Huang L, Thompson LM, Marsh JL. Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. The Journal of Biological Chemistry. 284: 29427-36. PMID 19710014 DOI: 10.1074/Jbc.M109.013193 |
0.51 |
|
2009 |
Bourasset F, Ouellet M, Tremblay C, Julien C, Do TM, Oddo S, LaFerla F, Calon F. Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease. Neuropharmacology. 56: 808-13. PMID 19705573 DOI: 10.1016/J.Neuropharm.2009.01.006 |
0.692 |
|
2009 |
Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 13594-9. PMID 19633196 DOI: 10.1073/Pnas.0901402106 |
0.829 |
|
2009 |
Fonseca MI, Ager RR, Chu SH, Yazan O, Sanderson SD, LaFerla FM, Taylor SM, Woodruff TM, Tenner AJ. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 1375-83. PMID 19561098 DOI: 10.4049/Jimmunol.0901005 |
0.496 |
|
2009 |
Ouellet M, Emond V, Chen CT, Julien C, Bourasset F, Oddo S, LaFerla F, Bazinet RP, Calon F. Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study. Neurochemistry International. 55: 476-82. PMID 19442696 DOI: 10.1016/J.Neuint.2009.04.018 |
0.551 |
|
2009 |
Kitazawa M, Vasilevko V, Cribbs DH, LaFerla FM. Immunization with amyloid-beta attenuates inclusion body myositis-like myopathology and motor impairment in a transgenic mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6132-41. PMID 19439591 DOI: 10.1523/Jneurosci.1150-09.2009 |
0.307 |
|
2009 |
Caccamo A, Fisher A, LaFerla FM. M1 agonists as a potential disease-modifying therapy for Alzheimer's disease. Current Alzheimer Research. 6: 112-7. PMID 19355845 DOI: 10.2174/156720509787602915 |
0.314 |
|
2009 |
McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006 |
0.78 |
|
2009 |
Lopes JP, Blurton-Jones M, Yamasaki TR, Agostinho P, LaFerla FM. Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not amyloid-beta and tau pathology. Journal of Alzheimer's Disease : Jad. 16: 541-9. PMID 19276549 DOI: 10.3233/Jad-2009-0993 |
0.849 |
|
2009 |
Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R. Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: an electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines. Journal of Alzheimer's Disease : Jad. 16: 315-23. PMID 19221421 DOI: 10.3233/Jad-2009-0962 |
0.623 |
|
2009 |
Kitazawa M, Cheng D, Laferla FM. Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD. Journal of Neurochemistry. 108: 1550-60. PMID 19183260 DOI: 10.1111/J.1471-4159.2009.05901.X |
0.42 |
|
2009 |
Guan H, Liu Y, Daily A, Police S, Kim MH, Oddo S, LaFerla FM, Pauly JR, Murphy MP, Hersh LB. Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease. Journal of Neuroscience Research. 87: 1462-73. PMID 19021293 DOI: 10.1002/Jnr.21944 |
0.628 |
|
2009 |
Morrissette DA, Parachikova A, Green KN, LaFerla FM. Relevance of transgenic mouse models to human Alzheimer disease. The Journal of Biological Chemistry. 284: 6033-7. PMID 18948253 DOI: 10.1074/Jbc.R800030200 |
0.805 |
|
2009 |
Gulinello M, Gertner M, Mendoza G, Schoenfeld BP, Oddo S, LaFerla F, Choi CH, McBride SM, Faber DS. Validation of a 2-day water maze protocol in mice. Behavioural Brain Research. 196: 220-7. PMID 18831990 DOI: 10.1016/J.Bbr.2008.09.002 |
0.6 |
|
2009 |
Oddo S, Caccamo A, Cheng D, LaFerla FM. Genetically altering Abeta distribution from the brain to the vasculature ameliorates tau pathology. Brain Pathology (Zurich, Switzerland). 19: 421-30. PMID 18657136 DOI: 10.1111/J.1750-3639.2008.00194.X |
0.664 |
|
2009 |
Knuesel I, Nyffeler M, Mormède C, Muhia M, Meyer U, Pietropaolo S, Yee BK, Pryce CR, LaFerla FM, Marighetto A, Feldon J. Age-related accumulation of Reelin in amyloid-like deposits. Neurobiology of Aging. 30: 697-716. PMID 17904250 DOI: 10.1016/J.Neurobiolaging.2007.08.011 |
0.436 |
|
2009 |
Hasegawa T, Mikoda N, Kitazawa M, LaFerla F. B6 deficient feeding or homocysteic acid induces the earlier Alzheimer’s pathological change in normal C57BL male mice Nature Precedings. DOI: 10.1038/Npre.2009.2764.1 |
0.314 |
|
2009 |
Martinez-Coria H, Green K, Banerjee P, LaFerla F. P.5.b.005 Combination of memantine and donepezil reverses cognitive deficits in transgenic mice with Alzheimer-type pathology European Neuropsychopharmacology. 19: S627. DOI: 10.1016/S0924-977X(09)71008-9 |
0.543 |
|
2009 |
LaFerla FM, Martinez-Coria H, Green KN, Banerjee PK. P4-334: Combination of memantine and donepezil reverses cognitive deficits in transgenic mice with both amyloid-beta plaques and neurofibrillary tangles Alzheimer's & Dementia. 5: e29-e29. DOI: 10.1016/j.jalz.2009.07.113 |
0.56 |
|
2009 |
Gimenez-Llort L, De Las Casas-Engel M, Laferla FM, De La Fuente M. P4-245: Decrease of the antioxidant defenses in 3xTg-AD triple-transgenic adult mice for Alzheimer's disease Alzheimer's & Dementia. 5: P502-P502. DOI: 10.1016/j.jalz.2009.04.711 |
0.413 |
|
2009 |
Vosseller K, Skorobogatko Y, Bryfogle JA, LaFerla FM, Vocadlo DJ, Tallent M. P4-228: O-GlcNAc regulation of hippocampal synaptic plasticity in wild type and 3xTg-AD mice Alzheimer's & Dementia. 5: P497-P497. DOI: 10.1016/J.Jalz.2009.04.694 |
0.301 |
|
2009 |
Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R. P2-139: Amyloid plaques are formed in association with specific plasma membrane domains: An EM-immunogold 3-D-reconstruction study Alzheimer's & Dementia. 5: P302-P302. DOI: 10.1016/J.Jalz.2009.04.450 |
0.499 |
|
2009 |
Hoffmann NA, Bittner T, Burgold S, LaFerla FM, Kretzschmar HA, Herms J. P3-181: Ultrastructural investigation of tau-dependent dendropathy in a triple transgenic mouse model of Alzheimer's disease Alzheimer's & Dementia. 5: P396-P397. DOI: 10.1016/J.Jalz.2009.04.1055 |
0.389 |
|
2008 |
Oddo S, Caccamo A, Tseng B, Cheng D, Vasilevko V, Cribbs DH, LaFerla FM. Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12163-75. PMID 19020010 DOI: 10.1523/Jneurosci.2464-08.2008 |
0.848 |
|
2008 |
Green KN, Steffan JS, Martinez-Coria H, Sun X, Schreiber SS, Thompson LM, LaFerla FM. Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11500-10. PMID 18987186 DOI: 10.1523/Jneurosci.3203-08.2008 |
0.605 |
|
2008 |
Janelsins MC, Mastrangelo MA, Park KM, Sudol KL, Narrow WC, Oddo S, LaFerla FM, Callahan LM, Federoff HJ, Bowers WJ. Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. The American Journal of Pathology. 173: 1768-82. PMID 18974297 DOI: 10.2353/Ajpath.2008.080528 |
0.64 |
|
2008 |
Rodríguez JJ, Jones VC, Tabuchi M, Allan SM, Knight EM, LaFerla FM, Oddo S, Verkhratsky A. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. Plos One. 3: e2935. PMID 18698410 DOI: 10.1371/Journal.Pone.0002935 |
0.691 |
|
2008 |
Green KN, LaFerla FM. Linking calcium to Abeta and Alzheimer's disease. Neuron. 59: 190-4. PMID 18667147 DOI: 10.1016/j.neuron.2008.07.013 |
0.509 |
|
2008 |
Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. The Journal of General Physiology. 132: i1. PMID 18663130 DOI: 10.1085/Jgp1322Oia1 |
0.697 |
|
2008 |
Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. The Journal of Cell Biology. 181: 1107-16. PMID 18591429 DOI: 10.1083/Jcb.200706171 |
0.72 |
|
2008 |
Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, et al. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Research. 1216: 92-103. PMID 18486110 DOI: 10.1016/J.Brainres.2008.03.079 |
0.463 |
|
2008 |
McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Research. 1207: 225-36. PMID 18374906 DOI: 10.1016/J.Brainres.2008.01.095 |
0.689 |
|
2008 |
Lopez JR, Lyckman A, Oddo S, Laferla FM, Querfurth HW, Shtifman A. Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice. Journal of Neurochemistry. 105: 262-71. PMID 18021291 DOI: 10.1111/J.1471-4159.2007.05135.X |
0.549 |
|
2008 |
Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. Congo red and thioflavin-T analogs detect Abeta oligomers. Journal of Neurochemistry. 104: 457-68. PMID 17953662 DOI: 10.1111/J.1471-4159.2007.04972.X |
0.599 |
|
2008 |
Tseng BP, Green KN, Chan JL, Blurton-Jones M, LaFerla FM. Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiology of Aging. 29: 1607-18. PMID 17544172 DOI: 10.1016/J.Neurobiolaging.2007.04.014 |
0.852 |
|
2008 |
Green KN, Martinez-Coria H, Banerjee PK, Gupta S, LaFerla FM. P1-081: Memantine reduces amyloid and Tau pathologies in a triple-transgenic mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T230-T230. DOI: 10.1016/j.jalz.2008.05.667 |
0.617 |
|
2008 |
Oddo S, Caccamo A, Tseng B, Cheng D, Vasilevko V, Cribbs DH, LaFerla FM. O2-02-06: Blocking Aβ42 accumulation delays the onset and progression of Tau pathology and cognitive decline via CHIP: A mechanistic link between Aβ and Tau pathology Alzheimer's & Dementia. 4: T134-T134. DOI: 10.1016/J.Jalz.2008.05.318 |
0.634 |
|
2008 |
Coakley MF, Moloney AM, Oddo S, LaFerla FM, O' Neill C. P4-251: Changes in Akt and IGF-1 receptor signaling relate to developing Abeta and tangle pathology in the triple transgenic model of Alzheimer's disease Alzheimer's & Dementia. 4: T745-T745. DOI: 10.1016/J.Jalz.2008.05.2320 |
0.613 |
|
2008 |
LaFerla FM. PL-01-01: Mouse models of Alzheimer's disease Alzheimer's & Dementia. 4: T98-T99. DOI: 10.1016/j.jalz.2008.05.179 |
0.324 |
|
2007 |
Green KN, Smith IF, Laferla FM. Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models. Sub-Cellular Biochemistry. 45: 507-21. PMID 18193650 |
0.546 |
|
2007 |
Carroll JC, Rosario ER, Chang L, Stanczyk FZ, Oddo S, LaFerla FM, Pike CJ. Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13357-65. PMID 18045930 DOI: 10.1523/Jneurosci.2718-07.2007 |
0.659 |
|
2007 |
Yamasaki TR, Blurton-Jones M, Morrissette DA, Kitazawa M, Oddo S, LaFerla FM. Neural stem cells improve memory in an inducible mouse model of neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11925-33. PMID 17978032 DOI: 10.1523/Jneurosci.1627-07.2007 |
0.785 |
|
2007 |
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, et al. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry. 103: 1132-44. PMID 17683481 DOI: 10.1111/J.1471-4159.2007.04829.X |
0.709 |
|
2007 |
Clinton LK, Billings LM, Green KN, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM. Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiology of Disease. 28: 76-82. PMID 17659878 DOI: 10.1016/J.Nbd.2007.06.013 |
0.814 |
|
2007 |
LaFerla FM, Green KN, Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nature Reviews. Neuroscience. 8: 499-509. PMID 17551515 DOI: 10.1038/Nrn2168 |
0.706 |
|
2007 |
Matsuoka Y, Gray AJ, Hirata-Fukae C, Minami SS, Waterhouse EG, Mattson MP, LaFerla FM, Gozes I, Aisen PS. Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage. Journal of Molecular Neuroscience : Mn. 31: 165-70. PMID 17478890 DOI: 10.1385/Jmn/31:02:165 |
0.468 |
|
2007 |
Oddo S, Caccamo A, Cheng D, Jouleh B, Torp R, LaFerla FM. Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice. Journal of Neurochemistry. 102: 1053-63. PMID 17472708 DOI: 10.1111/J.1471-4159.2007.04607.X |
0.676 |
|
2007 |
Caccamo A, Oddo S, Tran LX, LaFerla FM. Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles. The American Journal of Pathology. 170: 1669-75. PMID 17456772 DOI: 10.2353/Ajpath.2007.061178 |
0.626 |
|
2007 |
Green KN, Martinez-Coria H, Khashwji H, Hall EB, Yurko-Mauro KA, Ellis L, LaFerla FM. Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4385-95. PMID 17442823 DOI: 10.1523/JNEUROSCI.0055-07.2007 |
0.563 |
|
2007 |
Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla F. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Annals of the New York Academy of Sciences. 1097: 265-77. PMID 17413028 DOI: 10.1196/Annals.1379.025 |
0.605 |
|
2007 |
Halagappa VK, Guo Z, Pearson M, Matsuoka Y, Cutler RG, Laferla FM, Mattson MP. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 26: 212-20. PMID 17306982 DOI: 10.1016/J.Nbd.2006.12.019 |
0.4 |
|
2007 |
Billings LM, Green KN, McGaugh JL, LaFerla FM. Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 751-61. PMID 17251414 DOI: 10.1523/JNEUROSCI.4800-06.2007 |
0.583 |
|
2007 |
Giménez-Llort L, Blázquez G, Cañete T, Johansson B, Oddo S, Tobeña A, LaFerla FM, Fernández-Teruel A. Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid. Neuroscience and Biobehavioral Reviews. 31: 125-47. PMID 17055579 DOI: 10.1016/J.Neubiorev.2006.07.007 |
0.705 |
|
2007 |
Zhou J, Fonseca MI, Billings-Luhr L, Kayed R, Glabe CG, LaFerla F, Tenner AJ. Effect of immunization with the oligomeric form of the Aβ peptide: Reduction of senile plaque area, decreased complement C3 deposition and synthesis, and decline in behavioral function in a murine model of Alzheimer's disease Molecular Immunology. 44: 264-265. DOI: 10.1016/J.Molimm.2006.07.277 |
0.426 |
|
2007 |
Green K, Martinez-Coria H, Hall E, Yurko-Mauro K, Ellis L, LaFerla F. P-191: Dietary DHA ameliorates amyloid-β and tau pathology via a mechanism involving presenilin 1 levels Alzheimer's & Dementia. 3: S159-S159. DOI: 10.1016/J.Jalz.2007.04.154 |
0.561 |
|
2007 |
Banerjee P, Tanila H, Wisniewski T, Gupta S, LaFerla F, Lahiri DK. P-188: Memantine lowers amyloid beta levels in neuronal cells and transgenic mouse models of Alzheimer's disease Alzheimer's & Dementia. 3: S158-S158. DOI: 10.1016/J.Jalz.2007.04.151 |
0.472 |
|
2006 |
Rosario ER, Carroll JC, Oddo S, LaFerla FM, Pike CJ. Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13384-9. PMID 17182789 DOI: 10.1523/Jneurosci.2514-06.2006 |
0.688 |
|
2006 |
Blurton-Jones M, Laferla FM. Pathways by which Abeta facilitates tau pathology. Current Alzheimer Research. 3: 437-48. PMID 17168643 DOI: 10.2174/156720506779025242 |
0.69 |
|
2006 |
Oddo S, Vasilevko V, Caccamo A, Kitazawa M, Cribbs DH, LaFerla FM. Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles. The Journal of Biological Chemistry. 281: 39413-23. PMID 17056594 DOI: 10.1074/Jbc.M608485200 |
0.687 |
|
2006 |
Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9047-56. PMID 16943563 DOI: 10.1523/Jneurosci.2797-06.2006 |
0.63 |
|
2006 |
Moussa CE, Fu Q, Kumar P, Shtifman A, Lopez JR, Allen PD, LaFerla F, Weinberg D, Magrane J, Aprahamian T, Walsh K, Rosen KM, Querfurth HW. Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2165-7. PMID 16940437 DOI: 10.1096/Fj.06-5763Fje |
0.45 |
|
2006 |
Heredia L, Helguera P, de Olmos S, Kedikian G, Solá Vigo F, LaFerla F, Staufenbiel M, de Olmos J, Busciglio J, Cáceres A, Lorenzo A. Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6533-42. PMID 16775141 DOI: 10.1523/Jneurosci.5567-05.2006 |
0.491 |
|
2006 |
Kitazawa M, Green KN, Caccamo A, LaFerla FM. Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice. The American Journal of Pathology. 168: 1986-97. PMID 16723713 DOI: 10.2353/Ajpath.2006.051232 |
0.554 |
|
2006 |
Stutzmann GE, Smith I, Caccamo A, Oddo S, Laferla FM, Parker I. Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5180-9. PMID 16687509 DOI: 10.1523/Jneurosci.0739-06.2006 |
0.607 |
|
2006 |
Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron. 49: 671-82. PMID 16504943 DOI: 10.1016/J.Neuron.2006.01.020 |
0.736 |
|
2006 |
Oddo S, LaFerla FM. The role of nicotinic acetylcholine receptors in Alzheimer's disease. Journal of Physiology, Paris. 99: 172-9. PMID 16448808 DOI: 10.1016/J.Jphysparis.2005.12.080 |
0.679 |
|
2006 |
Oddo S, Caccamo A, Smith IF, Green KN, LaFerla FM. A dynamic relationship between intracellular and extracellular pools of Abeta. The American Journal of Pathology. 168: 184-94. PMID 16400022 DOI: 10.2353/Ajpath.2006.050593 |
0.714 |
|
2006 |
Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM. Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. The Journal of Biological Chemistry. 281: 1599-604. PMID 16282321 DOI: 10.1074/Jbc.M507892200 |
0.664 |
|
2006 |
Janelsins MC, Mastrangelo MA, Park KM, Fowlkes KL, Kinsky M, Narrow WC, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. 248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model Molecular Therapy. 13: S95. DOI: 10.1016/J.Ymthe.2006.08.275 |
0.658 |
|
2006 |
Martini AC, Forner S, Arboledas AG, Cunha C, Baglietto-Vargas D, Trujillo-Estrada L, Medeiros R, LaFerla F. P2-172: THE DYSREGULATION OF TOM1 IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P734-P734. DOI: 10.1016/J.Jalz.2018.06.859 |
0.4 |
|
2006 |
Baglietto-Vargas D, Cai L, Forner S, Martini A, Trujillo-Estrada L, Cunha C, Mortazavi A, Wood MA, Green KN, Macgregor GR, Tenner A, LaFerla F. O1-01-04: HAβ-KI: A KNOCK-IN MOUSE MODEL FOR SPORADIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P213-P213. DOI: 10.1016/J.Jalz.2018.06.2333 |
0.395 |
|
2006 |
Forner S, Baglietto-Vargas D, Limon A, Martini AC, Zhen Dur Chang AV, Trujillo-Estrada L, Cunha C, LaFerla F. P3-173: IMPACT OF SYNAPTIC REGULATORS’ LOSS ON ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1134-P1134. DOI: 10.1016/J.Jalz.2018.06.1531 |
0.388 |
|
2006 |
Lamb BT, Oblak AL, Williams HM, Baglietto-Vargas D, Wood MA, Mortazavi A, Green KN, Carter GW, Sukoff Rizzo SJ, Territo P, Sasner M, Macgregor GR, Tenner A, LaFerla F, Howell G. P1-131: MODEL-AD: LATE-ONSET ALZHEIMER'S DISEASE MODELS Alzheimer's & Dementia. 14: P321-P321. DOI: 10.1016/J.Jalz.2018.06.134 |
0.467 |
|
2006 |
Oblak AL, Williams HM, Baglietto-Vargas D, Mortazavi A, Wood MA, Green KN, Carter GW, Territo P, Sukoff Rizzo SJ, Sasner M, Macgregor GR, Tenner A, LaFerla F, Howell G, Lamb BT. P1-130: MODEL-AD: CHARACTERIZATION OF FAMILIAL AD MODELS (5XFAD, APP/PS1, HTAU, 3XTG-AD) Alzheimer's & Dementia. 14: P321-P321. DOI: 10.1016/J.Jalz.2018.06.133 |
0.466 |
|
2006 |
Caccamo A, Oddo S, Fisher A, LaFerla FM. P1-451: M1 receptors play a central role in modulating AD-like pathology in transgenic mice Alzheimer's & Dementia. 2: S230-S230. DOI: 10.1016/J.Jalz.2006.05.830 |
0.6 |
|
2006 |
Rosario ER, Carroll JC, Chang L, Stanczyk F, Oddo S, LaFerla F, Pike CJ. P1-252: Androgens regulate development of neuropathology in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 2: S170-S170. DOI: 10.1016/J.Jalz.2006.05.629 |
0.637 |
|
2006 |
Stutzmann GE, Smith I, Caccamo A, Oddo S, LaFerla F, Parker I. P1-125: Enhanced ryanodine receptor recruitment contributes to Ca2+
disruptions in young, adult and aged Alzheimer disease mice Alzheimer's & Dementia. 2: S132-S132. DOI: 10.1016/J.Jalz.2006.05.501 |
0.61 |
|
2006 |
Fisher A, Caccamo A, Oddo S, Billings LM, Green KN, Brandeis R, Pittel Z, Barner N, Elkon H, Laferla FM. S4-04-02: M1 muscarinic agonists as a comprehensive therapy in Alzheimer's disease Alzheimer's & Dementia. 2: S73-S73. DOI: 10.1016/J.Jalz.2006.05.285 |
0.514 |
|
2006 |
Hersh LB, Guan H, Daily A, Murphy MP, Oddo S, LaFerla FM. O2-05-01: Peripheral expression of neprilysin decreases amyloid deposition in hAPP mice Alzheimer's & Dementia. 2: S39-S40. DOI: 10.1016/J.Jalz.2006.05.138 |
0.567 |
|
2006 |
Oddo S, Caccamo A, Vasilevko V, Cribbs DH, LaFerla FM. O1-06-04: Reduction of both soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles Alzheimer's & Dementia. 2: S21-S21. DOI: 10.1016/J.Jalz.2006.05.064 |
0.657 |
|
2005 |
Janelsins MC, Mastrangelo MA, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. Journal of Neuroinflammation. 2: 23. PMID 16232318 DOI: 10.1186/1742-2094-2-23 |
0.685 |
|
2005 |
Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8843-53. PMID 16192374 DOI: 10.1523/Jneurosci.2868-05.2005 |
0.845 |
|
2005 |
Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. Journal of Neurochemistry. 94: 1711-8. PMID 16156741 DOI: 10.1111/J.1471-4159.2005.03332.X |
0.689 |
|
2005 |
Smith IF, Green KN, LaFerla FM. Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium. 38: 427-37. PMID 16125228 DOI: 10.1016/j.ceca.2005.06.021 |
0.601 |
|
2005 |
LaFerla FM, Oddo S. Alzheimer's disease: Abeta, tau and synaptic dysfunction. Trends in Molecular Medicine. 11: 170-6. PMID 15823755 DOI: 10.1016/J.Molmed.2005.02.009 |
0.671 |
|
2005 |
Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron. 45: 675-88. PMID 15748844 DOI: 10.1016/J.Neuron.2005.01.040 |
0.719 |
|
2005 |
Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiology of Aging. 26: 645-54. PMID 15708439 DOI: 10.1016/J.Neurobiolaging.2004.06.013 |
0.788 |
|
2005 |
Oddo S, Caccamo A, Green KN, Liang K, Tran L, Chen Y, Leslie FM, LaFerla FM. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 3046-51. PMID 15705720 DOI: 10.1073/Pnas.0408500102 |
0.73 |
|
2004 |
Tseng BP, Kitazawa M, LaFerla FM. Amyloid beta-peptide: the inside story. Current Alzheimer Research. 1: 231-9. PMID 15975052 DOI: 10.2174/1567205043332045 |
0.814 |
|
2004 |
Kitazawa M, Yamasaki TR, LaFerla FM. Microglia as a potential bridge between the amyloid beta-peptide and tau. Annals of the New York Academy of Sciences. 1035: 85-103. PMID 15681802 DOI: 10.1196/Annals.1332.006 |
0.817 |
|
2004 |
Akbari Y, Hitt BD, Murphy MP, Dagher NN, Tseng BP, Green KN, Golde TE, LaFerla FM. Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity. Biochemical and Biophysical Research Communications. 322: 1145-52. PMID 15336962 DOI: 10.1016/J.Bbrc.2004.07.136 |
0.772 |
|
2004 |
Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM. Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron. 43: 321-32. PMID 15294141 DOI: 10.1016/J.Neuron.2004.07.003 |
0.659 |
|
2004 |
Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/Jci20640 |
0.82 |
|
2004 |
Bishop G, Coleman P, Crutcher K, David D, Kinoshita J, LaFerla F, Leissring M, Shepherd J, Therianos S, Wang R, Wilson A, Zhu M. Live discussion: how the other half lives - or the what, how, and where, of the AbetaPP intracellular domain. Journal of Alzheimer's Disease : Jad. 6: 193-9. PMID 15171221 DOI: 10.3233/Jad-2004-6212 |
0.589 |
|
2004 |
Shakkottai VG, Chou CH, Oddo S, Sailer CA, Knaus HG, Gutman GA, Barish ME, LaFerla FM, Chandy KG. Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. The Journal of Clinical Investigation. 113: 582-90. PMID 14966567 DOI: 10.1172/Jci200420216 |
0.544 |
|
2004 |
Gouras G, LaFerla F, Strobel G, Busciglio J, Almeida C, Geula C, Stenh C, Lee D, D'Andrea M, Nagele B, Takahashi R, Hartmann T, LeBlanc A, Dineley K, Koudinov A. Intraneuronal Aβ accumulation-more evidence, less controversy? Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 443-449. DOI: 10.3233/Jad-2004-6413 |
0.454 |
|
2004 |
Oddo S, Billings LM, LaFerla FM. P4-371 In vivo evidence linking Aβ and TAU Neurobiology of Aging. 25: S580. DOI: 10.1016/S0197-4580(04)81929-8 |
0.607 |
|
2004 |
Smith IF, Oddo S, Green KN, LaFerla FM. P2-119 Alterations of intracellular CA2+ homeostasis in a triple transgenic model (PS1M146V, APPSWE, TAUP301L) of Alzheimer's disease Neurobiology of Aging. 25: S258. DOI: 10.1016/S0197-4580(04)80866-2 |
0.669 |
|
2004 |
Billings LM, Oddo S, LaFerla FM. P2-073 Assessing cognitive impairments in the 3XTG-AD mice: correlations with plaque and tangle pathology Neurobiology of Aging. 25: S244-S245. DOI: 10.1016/S0197-4580(04)80820-0 |
0.639 |
|
2004 |
Furukawa K, Wang Y, Yao PJ, Mattson MP, Oddo S, LaFerla FM. P2-071 Ion channel properties of neurons from APP/PS1/TAU triple mutant mice Neurobiology of Aging. 25: S244. DOI: 10.1016/S0197-4580(04)80818-2 |
0.553 |
|
2004 |
LaFerla FM, Oddo S, Billings LM. O1-04-08 Antibody-mediated clearance of beta-amyloid reverses early TAU aggregates, but not late, hyperphosphorylated TAU Neurobiology of Aging. 25: S18. DOI: 10.1016/S0197-4580(04)80059-9 |
0.578 |
|
2003 |
Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM. Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiology of Aging. 24: 1063-70. PMID 14643377 DOI: 10.1016/J.Neurobiolaging.2003.08.012 |
0.862 |
|
2003 |
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 39: 409-21. PMID 12895417 DOI: 10.1016/S0896-6273(03)00434-3 |
0.827 |
|
2002 |
Sugarman MC, Yamasaki TR, Oddo S, Echegoyen JC, Murphy MP, Golde TE, Jannatipour M, Leissring MA, LaFerla FM. Inclusion body myositis-like phenotype induced by transgenic overexpression of beta APP in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 6334-9. PMID 11972038 DOI: 10.1073/Pnas.082545599 |
0.81 |
|
2002 |
Leissring MA, Murphy MP, Mead TR, Akbari Y, Sugarman MC, Jannatipour M, Anliker B, Müller U, Saftig P, De Strooper B, Wolfe MS, Golde TE, LaFerla FM. A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. Proceedings of the National Academy of Sciences of the United States of America. 99: 4697-702. PMID 11917117 DOI: 10.1073/Pnas.072033799 |
0.776 |
|
2001 |
Leissring MA, LaFerla FM, Callamaras N, Parker I. Subcellular mechanisms of presenilin-mediated enhancement of calcium signaling. Neurobiology of Disease. 8: 469-78. PMID 11442355 DOI: 10.1006/Nbdi.2001.0382 |
0.602 |
|
2001 |
Marchant JS, Stutzmann GE, Leissring MA, LaFerla FM, Parker I. Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. Nature Biotechnology. 19: 645-9. PMID 11433276 DOI: 10.1038/90249 |
0.569 |
|
2000 |
LaFerla FM, Sugarman MC, Lane TE, Leissring MA. Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma. Journal of Molecular Neuroscience : Mn. 15: 45-59. PMID 11211236 DOI: 10.1385/Jmn:15:1:45 |
0.628 |
|
2000 |
Leissring MA, Yamasaki TR, Wasco W, Buxbaum JD, Parker I, LaFerla FM. Calsenilin reverses presenilin-mediated enhancement of calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 97: 8590-3. PMID 10900016 DOI: 10.1073/Pnas.97.15.8590 |
0.787 |
|
2000 |
Cribbs DH, Azizeh BY, Cotman CW, LaFerla FM. Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide. Biochemistry. 39: 5988-94. PMID 10821670 DOI: 10.1021/bi000029f |
0.472 |
|
2000 |
Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, LaFerla FM. Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. The Journal of Cell Biology. 149: 793-8. PMID 10811821 DOI: 10.1083/Jcb.149.4.793 |
0.768 |
|
2000 |
Mattson MP, LaFerla FM, Chan SL, Leissring MA, Shepel PN, Geiger JD. Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends in Neurosciences. 23: 222-9. PMID 10782128 DOI: 10.1016/S0166-2236(00)01548-4 |
0.621 |
|
1999 |
Leissring MA, Parker I, LaFerla FM. Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals. The Journal of Biological Chemistry. 274: 32535-8. PMID 10551803 DOI: 10.1074/Jbc.274.46.32535 |
0.615 |
|
1999 |
Leissring MA, Paul BA, Parker I, Cotman CW, LaFerla FM. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes. Journal of Neurochemistry. 72: 1061-8. PMID 10037477 DOI: 10.1046/J.1471-4159.1999.0721061.X |
0.703 |
|
1998 |
Leissring MA, Sugarman MC, LaFerla FM. Herpes simplex virus infections and Alzheimer's disease. Implications for drug treatment and immunotherapy. Drugs & Aging. 13: 193-8. PMID 9789723 DOI: 10.2165/00002512-199813030-00002 |
0.682 |
|
1997 |
LaFerla FM, Troncoso JC, Strickland DK, Kawas CH, Jay G. Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization. The Journal of Clinical Investigation. 100: 310-20. PMID 9218507 DOI: 10.1172/Jci119536 |
0.369 |
|
1997 |
Weber LL, Leissring MA, Yang AJ, Glabe CG, Cribbs DH, LaFerla FM. Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques. Experimental Neurology. 143: 37-44. PMID 9000444 DOI: 10.1006/Exnr.1996.6348 |
0.686 |
|
1996 |
Cribbs DH, Chen LS, Cotman CW, LaFerla FM. Injury induces presenilin-1 gene expression in mouse brain. Neuroreport. 7: 1773-6. PMID 8905662 DOI: 10.1097/00001756-199607290-00016 |
0.454 |
|
1996 |
LaFerla FM, Hall CK, Ngo L, Jay G. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. The Journal of Clinical Investigation. 98: 1626-32. PMID 8833912 DOI: 10.1172/JCI118957 |
0.324 |
|
1995 |
LaFerla FM. The Alzheimer??s beta-amyloid peptide induces neurodegeneration and apoptotic cell death in transgenic mice Behavioural Pharmacology. 6: 55. DOI: 10.1097/00008877-199505001-00065 |
0.334 |
|
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