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Christopher B. Kelly, Ph.D. - Publications

Affiliations: 
2006-2010 Biochemistry Stonehill College, Easton, MA, United States 
 2010-2015 Chemistry University of Connecticut, Storrs, CT, United States 
 2015-2018 Chemistry University of Pennsylvania, Philadelphia, PA, United States 
 2018-2019 Chemistry Virginia Commonwealth University, Richmond, VA, United States 
 2019- Discovery Process Chemistry Janssen Research & Development 
Area:
Organofluorine, Carbocations, Oxoammonium Salts, Flow Chemistry, Catalysis
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dherange BD, Yuan M, Kelly CB, Reiher CA, Grosanu C, Berger KJ, Gutierrez O, Levin MD. Direct Deaminative Functionalization. Journal of the American Chemical Society. PMID 36548788 DOI: 10.1021/jacs.2c11453  0.317
2022 Kelly CB, Milligan JA, Tilley LJ, Sodano TM. Bicyclobutanes: from curiosities to versatile reagents and covalent warheads. Chemical Science. 13: 11721-11737. PMID 36320907 DOI: 10.1039/d2sc03948f  0.741
2020 Milligan JA, Burns KL, Le AV, Polites VC, Wang ZJ, Molander GA, Kelly CB. Radical-Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes. Advanced Synthesis & Catalysis. 362: 242-247. PMID 34084099 DOI: 10.1002/adsc.201901051  0.52
2020 Kelly CB, Padilla-Salinas R. Late Stage C-H Functionalization Via Chalcogen and Pnictogen Salts Chemical Science. DOI: 10.1039/D0Sc03833D  0.319
2019 Campbell MW, Compton JS, Kelly CB, Molander GA. Three-Component Olefin Dicarbofunctionalization Enabled by Nickel/Photoredox Dual Catalysis. Journal of the American Chemical Society. PMID 31833357 DOI: 10.1021/Jacs.9B08282  0.581
2019 Wang X, Davies GHM, Koschitzky A, Wisniewski SR, Kelly CB, Molander GA. Photoredox Catalysis Enables Access to N-Functionalized 2,1-Borazaronaphthalenes. Organic Letters. PMID 30916973 DOI: 10.1021/Acs.Orglett.9B00884  0.485
2019 Pantaine LRE, Milligan JA, Matsui JK, Kelly CB, Molander GA. Photoredox Radical/Polar Crossover Enables Construction of Saturated Nitrogen Heterocycles. Organic Letters. PMID 30860849 DOI: 10.1021/Acs.Orglett.9B00602  0.575
2019 Milligan JA, Burns KL, Le AV, Polites VC, Wang Z, Molander GA, Kelly CB. Radical‐Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes Advanced Synthesis & Catalysis. 362: 242-247. DOI: 10.1002/Adsc.201901051  0.494
2019 Engle SM, Kirkner TR, Kelly CB. Preparation of 2,4,5,6‐Tetra(9H‐Carbazol‐9‐yl)Isophthalonitrile Organic Syntheses. 96: 1-19. DOI: 10.1002/0471264229.Os096.28  0.768
2018 Milligan JA, Phelan JP, Polites VC, Kelly CB, Molander GA. Radical/Polar Annulation Reactions (RPARs) Enable the Modular Construction of Cyclopropanes. Organic Letters. PMID 30350660 DOI: 10.1021/Acs.Orglett.8B02968  0.573
2018 Phelan JP, Wiles RJ, Lang SB, Kelly CB, Molander GA. Correction: Rapid access to diverse, trifluoromethyl-substituted alkenes using complementary strategies. Chemical Science. 9: 5119. PMID 30090294 DOI: 10.1039/C8Sc90109K  0.755
2018 Compton JS, Saeednia B, Kelly CB, Molander GA. 3-Boryl-2,1-borazaronaphthalene: Umpolung Reagents for Diversifying Naphthalene Isosteres. The Journal of Organic Chemistry. PMID 29989812 DOI: 10.1021/Acs.Joc.8B01197  0.494
2018 Phelan JP, Lang SB, Compton JS, Kelly CB, Dykstra R, Gutierrez O, Molander GA. Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover. Journal of the American Chemical Society. PMID 29916711 DOI: 10.1021/Jacs.8B05243  0.791
2018 Phelan JP, Wiles RJ, Lang SB, Kelly CB, Molander GA. Rapid access to diverse, trifluoromethyl-substituted alkenes using complementary strategies. Chemical Science. 9: 3215-3220. PMID 29732105 DOI: 10.1039/C7Sc05420C  0.779
2018 Cabrera-Afonso MJ, Lu ZP, Kelly CB, Lang SB, Dykstra R, Gutierrez O, Molander GA. Engaging sulfinate salts Ni/photoredox dual catalysis enables facile C -SOR coupling. Chemical Science. 9: 3186-3191. PMID 29732101 DOI: 10.1039/C7Sc05402E  0.761
2017 Remeur C, Kelly CB, Patel NR, Molander GA. Aminomethylation of Aryl Halides using α-Silylamines Enabled by Ni/Photoredox Dual Catalysis. Acs Catalysis. 7: 6065-6069. PMID 29354317 DOI: 10.1021/Acscatal.7B01973  0.628
2017 Lin K, Kelly CB, Jouffroy M, Molander GA. Preparation of Diisopropylammonium Bis(catecholato)cyclohexylsilicate. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 94: 16-33. PMID 29200532 DOI: 10.15227/Orgsyn.094.0016  0.497
2017 Molander G, Lang SB, Wiles RJ, Kelly CB. Photoredox Enables the Construction of 1,1-Difluoroalkene Carbonyl Mimics. Angewandte Chemie (International Ed. in English). PMID 28960656 DOI: 10.1002/Anie.201709487  0.799
2017 Nandi J, Ovian JM, Kelly CB, Leadbeater NE. Oxidative functionalisation of alcohols and aldehydes via the merger of oxoammonium cations and photoredox catalysis. Organic & Biomolecular Chemistry. PMID 28929164 DOI: 10.1039/C7Ob02243C  0.8
2017 Lin K, Wiles RJ, Kelly CB, Davies GHM, Molander GA. Haloselective Cross-Coupling via Ni/Photoredox Dual Catalysis. Acs Catalysis. 7: 5129-5133. PMID 28804677 DOI: 10.1021/Acscatal.7B01773  0.788
2017 Davies GHM, Mukhtar A, Saeednia B, Sherafat F, Kelly CB, Molander GA. Azaborininones: Synthesis and Structural Analysis of a Carbonyl-Containing Class of Azaborines. The Journal of Organic Chemistry. PMID 28485935 DOI: 10.1021/Acs.Joc.7B00747  0.532
2017 Patel NR, Kelly CB, Siegenfeld AP, Molander GA. Mild, Redox-Neutral Alkylation of Imines Enabled by an Organic Photocatalyst. Acs Catalysis. 7: 1766-1770. PMID 28367354 DOI: 10.1021/Acscatal.6B03665  0.625
2017 Ovian JM, Kelly CB, Pistritto VA, Leadbeater NE. Accessing N-Acyl Azoles via Oxoammonium Salt-Mediated Oxidative Amidation. Organic Letters. PMID 28248527 DOI: 10.1021/Acs.Orglett.7B00060  0.832
2017 Kelly CB, Patel NR, Primer DN, Jouffroy M, Tellis JC, Molander GA. Preparation of visible-light-activated metal complexes and their use in photoredox/nickel dual catalysis. Nature Protocols. 12: 472-492. PMID 28151464 DOI: 10.1038/Nprot.2016.176  0.797
2016 Tellis JC, Kelly CB, Primer DN, Jouffroy M, Patel NR, Molander GA. Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp(3)-sp(2) Cross-Coupling. Accounts of Chemical Research. PMID 27379472 DOI: 10.1021/Acs.Accounts.6B00214  0.809
2016 Loman JJ, Carnaghan ER, Hamlin TA, Ovian JM, Kelly CB, Mercadante MA, Leadbeater NE. A combined computational and experimental investigation of the oxidative ring-opening of cyclic ethers by oxoammonium cations. Organic & Biomolecular Chemistry. PMID 27031501 DOI: 10.1039/C6Ob00347H  0.794
2016 Patel NR, Kelly CB, Jouffroy M, Molander GA. Correction to "Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis". Organic Letters. PMID 26977711 DOI: 10.1021/Acs.Orglett.6B00668  0.509
2016 Jouffroy M, Kelly CB, Molander GA. Thioetherification via Photoredox/Nickel Dual Catalysis. Organic Letters. PMID 26852821 DOI: 10.1021/Acs.Orglett.6B00208  0.59
2016 Patel NR, Kelly CB, Jouffroy M, Molander GA. Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis. Organic Letters. PMID 26828317 DOI: 10.1021/Acs.Orglett.6B00024  0.601
2016 Loman JJ, Pistritto VA, Kelly CB, Leadbeater NE. Oxidative Cleavage of Silyl Ethers by an Oxoammonium Salt Synlett. 27: 2372-2377. DOI: 10.1055/S-0035-1561498  0.679
2015 Hamlin TA, Kelly CB, Ovian JM, Wiles RJ, Tilley LJ, Leadbeater NE. Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model. The Journal of Organic Chemistry. 80: 8150-67. PMID 26167866 DOI: 10.1021/Acs.Joc.5B01240  0.784
2015 Kelly CB, Ovian JM, Cywar RM, Gosselin TR, Wiles RJ, Leadbeater NE. Oxidative cleavage of allyl ethers by an oxoammonium salt. Organic & Biomolecular Chemistry. 13: 4255-9. PMID 25748071 DOI: 10.1039/C5Ob00270B  0.789
2015 Kelly CB, Lambert KM, Mercadante MA, Ovian JM, Bailey WF, Leadbeater NE. Access to nitriles from aldehydes mediated by an oxoammonium salt. Angewandte Chemie (International Ed. in English). 54: 4241-5. PMID 25665019 DOI: 10.1002/Anie.201412256  0.827
2015 Hamlin TA, Kelly CB, Ovian JM, Wiles RJ, Tilley LJ, Leadbeater NE. Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model Journal of Organic Chemistry. 80: 8150-8167. DOI: 10.1021/acs.joc.5b01240  0.785
2015 Kelly CB, Mercadante MA, Carnaghan ER, Doherty MJ, Fager DC, Hauck JJ, Macinnis AE, Tilley LJ, Leadbeater NE. Synthesis of Perfluoroalkyl-Substituted Vinylcyclopropanes by Way of Enhanced Neighboring Group Participation European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.201500565  0.804
2014 Desrosiers JN, Kelly CB, Fandrick DR, Nummy L, Campbell SJ, Wei X, Sarvestani M, Lee H, Sienkiewicz A, Sanyal S, Zeng X, Grinberg N, Ma S, Song JJ, Senanayake CH. A scalable and regioselective synthesis of 2-difluoromethyl pyridines from commodity chemicals. Organic Letters. 16: 1724-7. PMID 24601851 DOI: 10.1021/Ol500402E  0.589
2014 Hamlin TA, Kelly CB, Cywar RM, Leadbeater NE. Methylenation of perfluoroalkyl ketones using a Peterson olefination approach. The Journal of Organic Chemistry. 79: 1145-55. PMID 24410210 DOI: 10.1021/Jo402577N  0.819
2014 Bobbitt JM, Bartelson AL, Bailey WF, Hamlin TA, Kelly CB. Oxoammonium salt oxidations of alcohols in the presence of pyridine bases. The Journal of Organic Chemistry. 79: 1055-67. PMID 24386938 DOI: 10.1021/Jo402519M  0.688
2014 Mercadante MA, Kelly CB, Hamlin TA, Delle Chiaie KR, Drago MD, Duffy KK, Dumas MT, Fager DC, Glod BLC, Hansen KE, Hill CR, Leising RM, Lynes CL, Macinnis AE, McGohey MR, et al. 1,3-γ-Silyl-elimination in electron-deficient cationic systems Chemical Science. 5: 3983-3994. DOI: 10.1039/C4Sc01732C  0.79
2014 Hamlin TA, Lazarus GML, Kelly CB, Leadbeater NE. A continuous-flow approach to 3,3,3-trifluoromethylpropenes: Bringing together grignard addition, peterson elimination, inline extraction, and solvent switching Organic Process Research and Development. 18: 1253-1258. DOI: 10.1021/Op500190J  0.711
2013 Kelly CB, Mercadante MA, Leadbeater NE. Trifluoromethyl ketones: properties, preparation, and application. Chemical Communications (Cambridge, England). 49: 11133-48. PMID 24162741 DOI: 10.1039/C3Cc46266H  0.787
2013 Kelly CB, Mercadante MA, Wiles RJ, Leadbeater NE. Oxidative esterification of aldehydes using a recyclable oxoammonium salt. Organic Letters. 15: 2222-5. PMID 23614873 DOI: 10.1021/Ol400785D  0.796
2013 Mercadante MA, Kelly CB, Bobbitt JM, Tilley LJ, Leadbeater NE. Synthesis of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate and 4-acetamido-(2,2,6,6-tetramethyl-piperidin-1-yl)oxyl and their use in oxidative reactions. Nature Protocols. 8: 666-76. PMID 23471111 DOI: 10.1038/Nprot.2013.028  0.833
2013 Hamlin TA, Kelly CB, Leadbeater NE. Dehydrogenation of perfluoroalkyl ketones by using a recyclable oxoammonium salt European Journal of Organic Chemistry. 3658-3661. DOI: 10.1002/Ejoc.201300392  0.748
2012 Kelly CB, Mercadante MA, Hamlin TA, Fletcher MH, Leadbeater NE. Oxidation of α-trifluoromethyl alcohols using a recyclable oxoammonium salt. The Journal of Organic Chemistry. 77: 8131-41. PMID 22931546 DOI: 10.1021/Jo301477S  0.826
2012 Rudzinski DM, Kelly CB, Leadbeater NE. A Weinreb amide approach to the synthesis of trifluoromethylketones. Chemical Communications (Cambridge, England). 48: 9610-2. PMID 22911019 DOI: 10.1039/C2Cc35037H  0.574
2012 Eddy NA, Kelly CB, Mercadante MA, Leadbeater NE, Fenteany G. Access to dienophilic ene-triketone synthons by oxidation of diketones with an oxoammonium salt. Organic Letters. 14: 498-501. PMID 22206582 DOI: 10.1021/Ol2030873  0.839
2012 Mercadante MA, Kelly CB, Lee C, Leadbeater NE. Continuous flow hydrogenation using an on-demand gas delivery reactor Organic Process Research and Development. 16: 1064-1068. DOI: 10.1021/Op300019W  0.769
2011 Kelly CB, Colthart AM, Constant BD, Corning SR, Dubois LN, Genovese JT, Radziewicz JL, Sletten EM, Whitaker KR, Tilley LJ. Enabling the synthesis of perfluoroalkyl bicyclobutanes via 1,3 γ-silyl elimination. Organic Letters. 13: 1646-9. PMID 21366262 DOI: 10.1021/Ol200121F  0.76
2011 Kelly CB, Lee C, Mercadante MA, Leadbeater NE. A continuous-flow approach to palladium-catalyzed alkoxycarbonylation reactions Organic Process Research and Development. 15: 717-720. DOI: 10.1021/Op200037N  0.793
2011 Kelly CB, Lee CX, Leadbeater NE. Copper-catalyzed direct preparation of diaryl sulfides from aryl iodides using potassium thiocyanate as a sulfur transfer reagent Tetrahedron Letters. 52: 4587-4589. DOI: 10.1016/J.Tetlet.2011.06.107  0.589
2011 Kelly CB, Lee C, Leadbeater NE. An approach for continuous-flow processing of reactions that involve the in situ formation of organic products Tetrahedron Letters. 52: 263-265. DOI: 10.1016/J.Tetlet.2010.11.027  0.533
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