| Year |
Citation |
Score |
| 2025 |
Turcotte EA, Kim K, Eislmayr KD, Goers L, Mitchell PS, Lesser CF, Vance RE. OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome. Biorxiv : the Preprint Server For Biology. PMID 39975412 DOI: 10.1101/2025.02.01.636075 |
0.391 |
|
| 2025 |
Eislmayr KD, Langner C, Liu FL, Yuvaraj S, Babirye JP, Roncaioli JL, Vickery JM, Barton GM, Lesser CF, Vance RE. Macrophages orchestrate elimination of from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ. Biorxiv : the Preprint Server For Biology. PMID 39896533 DOI: 10.1101/2025.01.20.633976 |
0.818 |
|
| 2024 |
Ravesloot-Chávez MM, Van Dis E, Fox D, Anaya Sanchez A, Espich S, Nguyenla XH, Rawal SL, Samani H, Ballinger MA, Thomas H, Kotov D, Vance R, Nachman MW, Stanley SA. Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils. Biorxiv : the Preprint Server For Biology. PMID 39211107 DOI: 10.1101/2023.06.29.547125 |
0.301 |
|
| 2024 |
Wong MP, Juan EYW, Pahmeier F, Chelluri SS, Wang P, Castillo-Rojas B, Blanc SF, Biering SB, Vance RE, Harris E. The inflammasome pathway is activated by dengue virus non-structural protein 1 and is protective during dengue virus infection. Plos Pathogens. 20: e1012167. PMID 38662771 DOI: 10.1371/journal.ppat.1012167 |
0.369 |
|
| 2023 |
Kotov DI, Lee OV, Fattinger SA, Langner CA, Guillen JV, Peters JM, Moon A, Burd EM, Witt KC, Stetson DB, Jaye DL, Bryson BD, Vance RE. Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis. Cell. 186: 5536-5553.e22. PMID 38029747 DOI: 10.1016/j.cell.2023.11.002 |
0.323 |
|
| 2023 |
Kotov DI, Lee OV, Ji DX, Jaye DL, Suliman S, Gabay C, Vance RE. Immunosuppression is a conserved driver of tuberculosis susceptibility. Biorxiv : the Preprint Server For Biology. PMID 37961447 DOI: 10.1101/2023.10.27.564420 |
0.732 |
|
| 2023 |
Wong MP, Juan EYW, Chelluri SS, Wang P, Pahmeier F, Castillo-Rojas B, Blanc SF, Biering SB, Vance RE, Harris E. The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection. Biorxiv : the Preprint Server For Biology. PMID 37790301 DOI: 10.1101/2023.09.21.558875 |
0.369 |
|
| 2023 |
Berry SB, Espich S, Thuong NTT, Chang X, Dorajoo R, Khor CC, Heng CK, Yuan JM, Fox D, Anaya-Sanchez A, Tenney L, Chang CJ, Kotov DI, Vance RE, Dunstan SJ, et al. Disruption of Aldehyde Dehydrogenase 2 protects against bacterial infection. Biorxiv : the Preprint Server For Biology. PMID 37662190 DOI: 10.1101/2023.08.24.554661 |
0.325 |
|
| 2023 |
Morrison HM, Craft J, Rivera-Lugo R, Johnson JR, Golovkine GR, Bell SL, Dodd CE, Van Dis E, Beatty WL, Margolis SR, Repasy T, Shaker I, Lee AY, Vance RE, Stanley SA, et al. Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens. Plos Pathogens. 19: e1011088. PMID 37352334 DOI: 10.1371/journal.ppat.1011088 |
0.825 |
|
| 2023 |
Tsu BV, Agarwal R, Gokhale NS, Kulsuptrakul J, Ryan AP, Fay EJ, Castro LK, Beierschmitt C, Yap C, Turcotte EA, Delgado-Rodriguez SE, Vance RE, Hyde JL, Savan R, Mitchell PS, et al. Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome. Plos Biology. 21: e3002144. PMID 37289745 DOI: 10.1371/journal.pbio.3002144 |
0.536 |
|
| 2023 |
Roncaioli JL, Babirye JP, Chavez RA, Liu FL, Turcotte EA, Lee AY, Lesser CF, Vance RE. A hierarchy of cell death pathways confers layered resistance to shigellosis in mice. Elife. 12. PMID 36645406 DOI: 10.7554/eLife.83639 |
0.813 |
|
| 2022 |
Remick BC, Gaidt MM, Vance RE. Effector-Triggered Immunity. Annual Review of Immunology. PMID 36750319 DOI: 10.1146/annurev-immunol-101721-031732 |
0.338 |
|
| 2022 |
Tsu BV, Agarwal R, Gokhale NS, Kulsuptrakul J, Ryan AP, Castro LK, Beierschmitt CM, Turcotte EA, Fay EJ, Vance RE, Hyde JL, Savan R, Mitchell PS, Daugherty MD. Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome. Biorxiv : the Preprint Server For Biology. PMID 36172130 DOI: 10.1101/2022.09.21.508960 |
0.537 |
|
| 2021 |
Deets KA, Nichols Doyle R, Rauch I, Vance RE. Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen. Elife. 10. PMID 34939932 DOI: 10.7554/eLife.72082 |
0.788 |
|
| 2021 |
Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE. The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34903650 DOI: 10.1073/pnas.2109022118 |
0.817 |
|
| 2021 |
Gaidt MM, Morrow A, Fairgrieve MR, Karr JP, Yosef N, Vance RE. Self-guarding of MORC3 enables virulence factor-triggered immunity. Nature. PMID 34759314 DOI: 10.1038/s41586-021-04054-5 |
0.325 |
|
| 2021 |
Luchetti G, Roncaioli JL, Chavez RA, Schubert AF, Kofoed EM, Reja R, Cheung TK, Liang Y, Webster JD, Lehoux I, Skippington E, Reeder J, Haley B, Tan MW, Rose CM, ... ... Vance RE, et al. Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection. Cell Host & Microbe. PMID 34492225 DOI: 10.1016/j.chom.2021.08.010 |
0.82 |
|
| 2021 |
Ji DX, Witt KC, Kotov DI, Margolis SR, Louie A, Chevée V, Chen KJ, Gaidt M, Dhaliwal HS, Lee AY, Nishimura SL, Zamboni DS, Kramnik I, A Portnoy D, Darwin KH, ... Vance RE, et al. Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons. Elife. 10. PMID 34151776 DOI: 10.7554/eLife.67290 |
0.814 |
|
| 2021 |
Ji DX, Witt KC, Kotov DI, Margolis SR, Louie A, Chevée V, Chen KJ, Gaidt M, Dhaliwal HS, Lee AY, Nishimura SL, Zamboni DS, Kramnik I, A Portnoy D, Darwin KH, ... Vance RE, et al. Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons. Elife. 10. PMID 34151776 DOI: 10.7554/eLife.67290 |
0.814 |
|
| 2021 |
Deets KA, Vance RE. Inflammasomes and adaptive immune responses. Nature Immunology. PMID 33603227 DOI: 10.1038/s41590-021-00869-6 |
0.809 |
|
| 2021 |
Chuang HC, Nichols EK, Rauch I, Chang WC, Lin PM, Misra R, Kitaoka M, Vance RE, Saijo K. Lytic cell death in specific microglial subsets is required for preventing atypical behavior in mice. Eneuro. PMID 33414187 DOI: 10.1523/ENEURO.0342-20.2020 |
0.682 |
|
| 2020 |
Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE. NAIP-NLRC4-deficient mice are susceptible to shigellosis. Elife. 9. PMID 33074100 DOI: 10.7554/eLife.59022 |
0.804 |
|
| 2020 |
Duxbury Z, Wang S, MacKenzie CI, Tenthorey JL, Zhang X, Huh SU, Hu L, Hill L, Ngou PM, Ding P, Chen J, Ma Y, Guo H, Castel B, Moschou PN, ... ... Vance RE, et al. Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants. Proceedings of the National Academy of Sciences of the United States of America. PMID 32709746 DOI: 10.1073/Pnas.2001185117 |
0.781 |
|
| 2020 |
Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL. Molecular characterization of a fungal gasdermin-like protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 32703806 DOI: 10.1073/Pnas.2004876117 |
0.807 |
|
| 2020 |
Yamashiro LH, Wilson SC, Morrison HM, Karalis V, Chung JJ, Chen KJ, Bateup HS, Szpara ML, Lee AY, Cox JS, Vance RE. Interferon-independent STING signaling promotes resistance to HSV-1 in vivo. Nature Communications. 11: 3382. PMID 32636381 DOI: 10.1038/S41467-020-17156-X |
0.825 |
|
| 2020 |
Dang EV, Madhani HD, Vance RE. Cholesterol in quarantine. Nature Immunology. PMID 32514065 DOI: 10.1038/S41590-020-0712-7 |
0.307 |
|
| 2020 |
Tenthorey JL, Chavez RA, Thompson TW, Deets KA, Vance RE, Rauch I. NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma. The Journal of Experimental Medicine. 217. PMID 32342103 DOI: 10.1084/Jem.20191736 |
0.812 |
|
| 2020 |
Ji DX, Yamashiro LH, Chen KJ, Mukaida N, Kramnik I, Darwin KH, Vance RE. Publisher Correction: Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. Nature Microbiology. PMID 32300234 DOI: 10.1038/S41564-020-0718-9 |
0.768 |
|
| 2020 |
Burke TP, Engström P, Chavez RA, Fonbuena JA, Vance RE, Welch MD. Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis. Nature Microbiology. PMID 32123346 DOI: 10.1038/S41564-020-0673-5 |
0.484 |
|
| 2019 |
Price JV, Russo D, Ji DX, Chavez RA, DiPeso L, Lee AY, Coers J, Vance RE. IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila. Mbio. 10. PMID 31719183 DOI: 10.1128/Mbio.02629-19 |
0.824 |
|
| 2019 |
Ji DX, Yamashiro LH, Chen KJ, Mukaida N, Kramnik I, Darwin KH, Vance RE. Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. Nature Microbiology. PMID 31611644 DOI: 10.1038/S41564-019-0578-3 |
0.809 |
|
| 2019 |
Haloupek N, Grob P, Tenthorey J, Vance RE, Nogales E. Cryo-EM studies of NAIP-NLRC4 inflammasomes. Methods in Enzymology. 625: 177-204. PMID 31455527 DOI: 10.1016/Bs.Mie.2019.04.030 |
0.793 |
|
| 2019 |
Gonçalves AV, Margolis SR, Quirino GFS, Mascarenhas DPA, Rauch I, Nichols RD, Ansaldo E, Fontana MF, Vance RE, Zamboni DS. Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila. Plos Pathogens. 15: e1007886. PMID 31251782 DOI: 10.1371/Journal.Ppat.1007886 |
0.795 |
|
| 2019 |
Mitchell PS, Sandstrom A, Vance RE. The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries. Current Opinion in Immunology. 60: 37-45. PMID 31121538 DOI: 10.1016/J.Coi.2019.04.015 |
0.822 |
|
| 2019 |
Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE. Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes. Science (New York, N.Y.). PMID 30872533 DOI: 10.1126/Science.Aau1330 |
0.821 |
|
| 2019 |
Vance RE. Decision letter: LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis Elife. DOI: 10.7554/Elife.51071.Sa1 |
0.347 |
|
| 2018 |
Marcus A, Mao AJ, Lensink-Vasan M, Wang L, Vance RE, Raulet DH. Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response. Immunity. 49: 754-763.e4. PMID 30332631 DOI: 10.1016/J.Immuni.2018.09.016 |
0.577 |
|
| 2018 |
Price JV, Jiang K, Galantowicz A, Freifeld A, Vance RE. is directly sensitive to 2-deoxyglucose-phosphate via its UhpC transporter but is indifferent to shifts in host cell glycolytic metabolism. Journal of Bacteriology. PMID 29784886 DOI: 10.1128/Jb.00176-18 |
0.762 |
|
| 2018 |
Sandstrom A, Vance RE. Defusing inflammasomes. The Journal of Experimental Medicine. PMID 29440361 DOI: 10.1084/jem.20180241 |
0.769 |
|
| 2017 |
Nichols RD, von Moltke J, Vance RE. NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease. Nature Communications. 8: 2209. PMID 29263322 DOI: 10.1038/S41467-017-02266-W |
0.755 |
|
| 2017 |
De Leon JA, Qiu J, Nicolai CJ, Counihan JL, Barry KC, Xu L, Lawrence RE, Castellano BM, Zoncu R, Nomura DK, Luo ZQ, Vance RE. Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors. Cell Reports. 21: 2031-2038. PMID 29166595 DOI: 10.1016/J.Celrep.2017.10.088 |
0.685 |
|
| 2017 |
DiPeso L, Ji DX, Vance RE, Price JV. Cell death and cell lysis are separable events during pyroptosis. Cell Death Discovery. 3: 17070. PMID 29147575 DOI: 10.1038/Cddiscovery.2017.70 |
0.79 |
|
| 2017 |
Tenthorey JL, Haloupek N, López-Blanco JR, Grob P, Adamson E, Hartenian E, Lind NA, Bourgeois NM, Chacón P, Nogales E, Vance RE. The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science (New York, N.Y.). 358: 888-893. PMID 29146805 DOI: 10.1126/Science.Aao1140 |
0.821 |
|
| 2017 |
Vance RE, Eichberg MJ, Portnoy DA, Raulet DH. Listening to each other: Infectious disease and cancer immunology. Science Immunology. 2. PMID 28783669 DOI: 10.1126/Sciimmunol.Aai9339 |
0.562 |
|
| 2017 |
Margolis SR, Wilson SC, Vance RE. Evolutionary Origins of cGAS-STING Signaling. Trends in Immunology. PMID 28416447 DOI: 10.1016/J.It.2017.03.004 |
0.826 |
|
| 2017 |
Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. PMID 28410991 DOI: 10.1016/J.Immuni.2017.03.016 |
0.802 |
|
| 2017 |
Barry KC, Ingolia NT, Vance RE. Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. Elife. 6. PMID 28383283 DOI: 10.7554/Elife.22707 |
0.738 |
|
| 2017 |
Barry KC, Ingolia NT, Vance RE. Author response: Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen Elife. DOI: 10.7554/Elife.22707.022 |
0.695 |
|
| 2016 |
Jones JD, Vance RE, Dangl JL. Intracellular innate immune surveillance devices in plants and animals. Science (New York, N.Y.). 354. PMID 27934708 DOI: 10.1126/Science.Aaf6395 |
0.406 |
|
| 2016 |
Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE. Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation. Plos Pathogens. 12: e1006052. PMID 27926929 DOI: 10.1371/Journal.Ppat.1006052 |
0.821 |
|
| 2016 |
Vance RE. Cytosolic DNA Sensing: The Field Narrows. Immunity. 45: 227-8. PMID 27533006 DOI: 10.1016/J.Immuni.2016.08.006 |
0.335 |
|
| 2016 |
Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE. NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo. The Journal of Experimental Medicine. PMID 27045008 DOI: 10.1084/Jem.20151809 |
0.814 |
|
| 2015 |
Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE. Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Molecular Cell. 59: 891-903. PMID 26300263 DOI: 10.1016/J.Molcel.2015.07.022 |
0.587 |
|
| 2015 |
Watson RO, Bell SL, MacDuff DA, Kimmey JM, Diner EJ, Olivas J, Vance RE, Stallings CL, Virgin HW, Cox JS. The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy. Cell Host & Microbe. 17: 811-9. PMID 26048136 DOI: 10.1016/J.Chom.2015.05.004 |
0.819 |
|
| 2015 |
Chavarría-Smith J, Vance RE. The NLRP1 inflammasomes. Immunological Reviews. 265: 22-34. PMID 25879281 DOI: 10.1111/Imr.12283 |
0.836 |
|
| 2015 |
Vance RE. The NAIP/NLRC4 inflammasomes. Current Opinion in Immunology. 32: 84-9. PMID 25621709 DOI: 10.1016/J.Coi.2015.01.010 |
0.439 |
|
| 2014 |
Price JV, Vance RE. The macrophage paradox. Immunity. 41: 685-93. PMID 25517611 DOI: 10.1016/J.Immuni.2014.10.015 |
0.758 |
|
| 2014 |
Cizauskas CA, Turner WC, Wagner B, Küsters M, Vance RE, Getz WM. Gastrointestinal helminths may affect host susceptibility to anthrax through seasonal immune trade-offs. Bmc Ecology. 14: 27. PMID 25388877 DOI: 10.1186/S12898-014-0027-3 |
0.412 |
|
| 2014 |
Kranzusch PJ, Lee AS, Wilson SC, Solovykh MS, Vance RE, Berger JM, Doudna JA. Structure-guided reprogramming of human cGAS dinucleotide linkage specificity. Cell. 158: 1011-21. PMID 25131990 DOI: 10.1016/J.Cell.2014.07.028 |
0.649 |
|
| 2014 |
Tenthorey JL, Kofoed EM, Daugherty MD, Malik HS, Vance RE. Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes. Molecular Cell. 54: 17-29. PMID 24657167 DOI: 10.1016/J.Molcel.2014.02.018 |
0.798 |
|
| 2014 |
Cizauskas CA, Bellan SE, Turner WC, Vance RE, Getz WM. Frequent and seasonally variable sublethal anthrax infections are accompanied by short-lived immunity in an endemic system. The Journal of Animal Ecology. 83: 1078-90. PMID 24499424 DOI: 10.1111/1365-2656.12207 |
0.407 |
|
| 2014 |
Diner EJ, Vance RE. Taking the STING out of cytosolic DNA sensing. Trends in Immunology. 35: 1-2. PMID 24231656 DOI: 10.1016/J.It.2013.10.011 |
0.797 |
|
| 2014 |
Glickman LH, Kanne DB, McWhirter SM, Leong ML, Lemmens EE, Metchette K, Vance RE, Pardoll DM, Dubensky TW. Abstract 2566: Activation of tumor-initiated T cell priming and tumor destruction with potent STING-activating cyclic dinucleotide derivatives Cancer Research. 74: 2566-2566. DOI: 10.1158/1538-7445.Am2014-2566 |
0.382 |
|
| 2013 |
Kranzusch PJ, Vance RE. cGAS dimerization entangles DNA recognition. Immunity. 39: 992-4. PMID 24332024 DOI: 10.1016/J.Immuni.2013.11.012 |
0.331 |
|
| 2013 |
Rayamajhi M, Zak DE, Chavarria-Smith J, Vance RE, Miao EA. Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein. Journal of Immunology (Baltimore, Md. : 1950). 191: 3986-9. PMID 24043898 DOI: 10.4049/Jimmunol.1301549 |
0.803 |
|
| 2013 |
Kofoed EM, Vance RE. Blue native polyacrylamide gel electrophoresis to monitor inflammasome assembly and composition. Methods in Molecular Biology (Clifton, N.J.). 1040: 169-83. PMID 23852604 DOI: 10.1007/978-1-62703-523-1_13 |
0.769 |
|
| 2013 |
Chavarría-Smith J, Vance RE. Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor. Plos Pathogens. 9: e1003452. PMID 23818853 DOI: 10.1371/Journal.Ppat.1003452 |
0.841 |
|
| 2013 |
Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC, Vance RE. The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. Cell Reports. 3: 1355-61. PMID 23707065 DOI: 10.1016/J.Celrep.2013.05.009 |
0.797 |
|
| 2013 |
Barry KC, Fontana MF, Portman JL, Dugan AS, Vance RE. IL-1α signaling initiates the inflammatory response to virulent Legionella pneumophila in vivo. Journal of Immunology (Baltimore, Md. : 1950). 190: 6329-39. PMID 23686480 DOI: 10.4049/Jimmunol.1300100 |
0.797 |
|
| 2013 |
Barker JR, Koestler BJ, Carpenter VK, Burdette DL, Waters CM, Vance RE, Valdivia RH. STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. Mbio. 4: e00018-13. PMID 23631912 DOI: 10.1128/Mbio.00018-13 |
0.799 |
|
| 2013 |
Conlon J, Burdette DL, Sharma S, Bhat N, Thompson M, Jiang Z, Rathinam VA, Monks B, Jin T, Xiao TS, Vogel SN, Vance RE, Fitzgerald KA. Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid. Journal of Immunology (Baltimore, Md. : 1950). 190: 5216-25. PMID 23585680 DOI: 10.4049/Jimmunol.1300097 |
0.769 |
|
| 2013 |
Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA. Caspase-11 protects against bacteria that escape the vacuole. Science (New York, N.Y.). 339: 975-8. PMID 23348507 DOI: 10.1126/Science.1230751 |
0.765 |
|
| 2013 |
Burdette DL, Vance RE. STING and the innate immune response to nucleic acids in the cytosol. Nature Immunology. 14: 19-26. PMID 23238760 DOI: 10.1038/Ni.2491 |
0.776 |
|
| 2013 |
von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. Recognition of bacteria by inflammasomes. Annual Review of Immunology. 31: 73-106. PMID 23215645 DOI: 10.1146/Annurev-Immunol-032712-095944 |
0.823 |
|
| 2013 |
Leong M, Kanne D, Glickman L, Lemmens E, Lauer P, Metchette K, Burdette D, Diner E, Fu J, Soares K, Brockstedt D, Portnoy D, Vance R, Kim Y, Jaffee E, et al. Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines Journal For Immunotherapy of Cancer. 1: O20. DOI: 10.1186/2051-1426-1-S1-O20 |
0.83 |
|
| 2012 |
von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, Vance RE. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature. 490: 107-11. PMID 22902502 DOI: 10.1038/Nature11351 |
0.778 |
|
| 2012 |
Fontana MF, Shin S, Vance RE. Activation of host mitogen-activated protein kinases by secreted Legionella pneumophila effectors that inhibit host protein translation. Infection and Immunity. 80: 3570-5. PMID 22851749 DOI: 10.1128/Iai.00557-12 |
0.789 |
|
| 2012 |
Ayres JS, Trinidad NJ, Vance RE. Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nature Medicine. 18: 799-806. PMID 22522562 DOI: 10.1038/Nm.2729 |
0.725 |
|
| 2012 |
Kofoed EM, Vance RE. NAIPs: building an innate immune barrier against bacterial pathogens. NAIPs function as sensors that initiate innate immunity by detection of bacterial proteins in the host cell cytosol. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 34: 589-98. PMID 22513803 DOI: 10.1002/Bies.201200013 |
0.794 |
|
| 2012 |
Ayres JS, Vance RE. Cellular teamwork in antibacterial innate immunity. Nature Immunology. 13: 115-7. PMID 22261960 DOI: 10.1038/Ni.2212 |
0.729 |
|
| 2011 |
Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 478: 515-8. PMID 21947006 DOI: 10.1038/Nature10429 |
0.828 |
|
| 2011 |
Fontana MF, Vance RE. Two signal models in innate immunity. Immunological Reviews. 243: 26-39. PMID 21884165 DOI: 10.1111/J.1600-065X.2011.01037.X |
0.765 |
|
| 2011 |
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 477: 592-5. PMID 21874021 DOI: 10.1038/Nature10394 |
0.801 |
|
| 2011 |
Fontana MF, Banga S, Barry KC, Shen X, Tan Y, Luo ZQ, Vance RE. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. Plos Pathogens. 7: e1001289. PMID 21390206 DOI: 10.1371/Journal.Ppat.1001289 |
0.832 |
|
| 2011 |
Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, Vance RE. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infection and Immunity. 79: 1606-14. PMID 21282416 DOI: 10.1128/Iai.01187-10 |
0.805 |
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| 2011 |
Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infection and Immunity. 79: 688-94. PMID 21098106 DOI: 10.1128/Iai.00999-10 |
0.834 |
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| 2010 |
Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host & Microbe. 8: 471-83. PMID 21147462 DOI: 10.1016/J.Chom.2010.11.007 |
0.771 |
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| 2010 |
Monroe KM, McWhirter SM, Vance RE. Induction of type I interferons by bacteria. Cellular Microbiology. 12: 881-90. PMID 20482555 DOI: 10.1111/J.1462-5822.2010.01478.X |
0.794 |
|
| 2010 |
Vance RE. Immunology taught by bacteria. Journal of Clinical Immunology. 30: 507-11. PMID 20373001 DOI: 10.1007/S10875-010-9389-2 |
0.466 |
|
| 2010 |
Vance RE. Inflammasome activation: how macrophages watch what they eat. Cell Host & Microbe. 7: 3-5. PMID 20114021 DOI: 10.1016/J.Chom.2009.12.011 |
0.365 |
|
| 2009 |
Monroe KM, McWhirter SM, Vance RE. Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. Plos Pathogens. 5: e1000665. PMID 19936053 DOI: 10.1371/Journal.Ppat.1000665 |
0.777 |
|
| 2009 |
McWhirter SM, Barbalat R, Monroe KM, Fontana MF, Hyodo M, Joncker NT, Ishii KJ, Akira S, Colonna M, Chen ZJ, Fitzgerald KA, Hayakawa Y, Vance RE. A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. The Journal of Experimental Medicine. 206: 1899-911. PMID 19652017 DOI: 10.1084/Jem.20082874 |
0.829 |
|
| 2009 |
Vance RE, Isberg RR, Portnoy DA. Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host & Microbe. 6: 10-21. PMID 19616762 DOI: 10.1016/J.Chom.2009.06.007 |
0.428 |
|
| 2008 |
Lightfield KL, Persson J, Brubaker SW, Witte CE, von Moltke J, Dunipace EA, Henry T, Sun YH, Cado D, Dietrich WF, Monack DM, Tsolis RM, Vance RE. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nature Immunology. 9: 1171-8. PMID 18724372 DOI: 10.1038/Ni.1646 |
0.815 |
|
| 2007 |
Persson J, Vance RE. Genetics-squared: combining host and pathogen genetics in the analysis of innate immunity and bacterial virulence. Immunogenetics. 59: 761-78. PMID 17874090 DOI: 10.1007/S00251-007-0248-0 |
0.738 |
|
| 2007 |
Coers J, Vance RE, Fontana MF, Dietrich WF. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cellular Microbiology. 9: 2344-57. PMID 17506816 DOI: 10.1111/J.1462-5822.2007.00963.X |
0.802 |
|
| 2006 |
Raulet DH, Vance RE. Self-tolerance of natural killer cells. Nature Reviews. Immunology. 6: 520-31. PMID 16799471 DOI: 10.1038/Nri1863 |
0.54 |
|
| 2006 |
Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. Plos Pathogens. 2: e18. PMID 16552444 DOI: 10.1371/Journal.Ppat.0020018 |
0.801 |
|
| 2006 |
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, Kuida K, Mariathasan S, Dixit VM, Flavell RA, Dietrich WF, Roy CR. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nature Immunology. 7: 318-25. PMID 16444259 DOI: 10.1038/Ni1305 |
0.807 |
|
| 2005 |
Kawamura H, Yagita H, Nisizawa T, Izumi N, Miyaji C, Vance RE, Raulet DH, Okumura K, Abo T. Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells. European Journal of Immunology. 35: 2358-66. PMID 15997467 DOI: 10.1002/Eji.200425933 |
0.549 |
|
| 2005 |
Vance RE, Rietsch A, Mekalanos JJ. Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo. Infection and Immunity. 73: 1706-13. PMID 15731071 DOI: 10.1128/Iai.73.3.1706-1713.2005 |
0.56 |
|
| 2005 |
Fernandez NC, Treiner E, Vance RE, Jamieson AM, Lemieux S, Raulet DH. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood. 105: 4416-23. PMID 15728129 DOI: 10.1182/Blood-2004-08-3156 |
0.677 |
|
| 2004 |
Vance RE, Hong S, Gronert K, Serhan CN, Mekalanos JJ. The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2135-9. PMID 14766977 DOI: 10.1073/Pnas.0307308101 |
0.55 |
|
| 2003 |
Tajima A, Tanaka T, Ebata T, Takeda K, Kawasaki A, Kelly JM, Darcy PK, Vance RE, Raulet DH, Kinoshita K, Okumura K, Smyth MJ, Yagita H. Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo. Journal of Immunology (Baltimore, Md. : 1950). 171: 1715-21. PMID 12902470 DOI: 10.4049/Jimmunol.171.4.1715 |
0.569 |
|
| 2003 |
Vance RE, Zhu J, Mekalanos JJ. A constitutively active variant of the quorum-sensing regulator LuxO affects protease production and biofilm formation in Vibrio cholerae. Infection and Immunity. 71: 2571-6. PMID 12704130 DOI: 10.1128/Iai.71.5.2571-2576.2003 |
0.541 |
|
| 2002 |
Lian RH, Maeda M, Lohwasser S, Delcommenne M, Nakano T, Vance RE, Raulet DH, Takei F. Orderly and nonstochastic acquisition of CD94/NKG2 receptors by developing NK cells derived from embryonic stem cells in vitro. Journal of Immunology (Baltimore, Md. : 1950). 168: 4980-7. PMID 11994449 DOI: 10.4049/Jimmunol.168.10.4980 |
0.559 |
|
| 2002 |
Fraser KP, Gays F, Robinson JH, van Beneden K, Leclercq G, Vance RE, Raulet DH, Brooks CG. NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time-dependent and stochastic manner independently of CD94 and NKG2. European Journal of Immunology. 32: 868-78. PMID 11870631 DOI: 10.1002/1521-4141(200203)32:3<868::Aid-Immu868>3.0.Co;2-A |
0.55 |
|
| 2002 |
Zhu J, Miller MB, Vance RE, Dziejman M, Bassler BL, Mekalanos JJ. Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proceedings of the National Academy of Sciences of the United States of America. 99: 3129-34. PMID 11854465 DOI: 10.1073/Pnas.052694299 |
0.554 |
|
| 2002 |
Vance RE, Jamieson AM, Cado D, Raulet DH. Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 868-73. PMID 11782535 DOI: 10.1073/Pnas.022500599 |
0.669 |
|
| 2001 |
Raulet DH, Vance RE, McMahon CW. Regulation of the natural killer cell receptor repertoire. Annual Review of Immunology. 19: 291-330. PMID 11244039 DOI: 10.1146/Annurev.Immunol.19.1.291 |
0.562 |
|
| 2000 |
Kraft JR, Vance RE, Pohl J, Martin AM, Raulet DH, Jensen PE. Analysis of Qa-1(b) peptide binding specificity and the capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes. The Journal of Experimental Medicine. 192: 613-24. PMID 10974028 DOI: 10.1084/Jem.192.5.613 |
0.514 |
|
| 2000 |
Vance RE. Cutting edge: cutting edge commentary: a Copernican revolution? Doubts about the danger theory. Journal of Immunology (Baltimore, Md. : 1950). 165: 1725-8. PMID 10925247 DOI: 10.4049/Jimmunol.165.4.1725 |
0.348 |
|
| 2000 |
Corral L, Hanke T, Vance RE, Cado D, Raulet DH. NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. European Journal of Immunology. 30: 920-30. PMID 10741410 DOI: 10.1002/1521-4141(200003)30:3<920::Aid-Immu920>3.0.Co;2-P |
0.566 |
|
| 1999 |
Vance RE, Jamieson AM, Raulet DH. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. The Journal of Experimental Medicine. 190: 1801-12. PMID 10601355 DOI: 10.1084/Jem.190.12.1801 |
0.677 |
|
| 1999 |
Zajac AJ, Vance RE, Held W, Sourdive DJ, Altman JD, Raulet DH, Ahmed R. Impaired anti-viral T cell responses due to expression of the Ly49A inhibitory receptor. Journal of Immunology (Baltimore, Md. : 1950). 163: 5526-34. PMID 10553080 |
0.569 |
|
| 1998 |
Hanke T, Corral L, Vance RE, Raulet DH. 2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen", is a lectin-like type II transmembrane receptor expressed by natural killer cells. European Journal of Immunology. 28: 4409-17. PMID 9862378 DOI: 10.1002/(Sici)1521-4141(199812)28:12<4409::Aid-Immu4409>3.0.Co;2-3 |
0.554 |
|
| 1998 |
Vance RE, Kraft JR, Altman JD, Jensen PE, Raulet DH. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). The Journal of Experimental Medicine. 188: 1841-8. PMID 9815261 DOI: 10.1084/Jem.188.10.1841 |
0.562 |
|
| 1998 |
Vance RE, Raulet DH. Toward a quantitative analysis of the repertoire of class I MHC-specific inhibitory receptors on natural killer cells. Current Topics in Microbiology and Immunology. 230: 135-60. PMID 9586355 DOI: 10.1007/978-3-642-46859-9_10 |
0.556 |
|
| 1997 |
Vance RE, Tanamachi DM, Hanke T, Raulet DH. Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells. European Journal of Immunology. 27: 3236-41. PMID 9464811 DOI: 10.1002/Eji.1830271222 |
0.782 |
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