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Marc C. Mumby - Publications

Affiliations: 
1983-2013 Pharmacology University of Texas Southwestern Medical Center, Dallas, TX, United States 
Website:
https://www.linkedin.com/in/marcmumby

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Hein AL, Seshacharyulu P, Rachagani S, Sheinin YM, Ouellette MM, Ponnusamy MP, Mumby MC, Batra SK, Yan Y. PR55α subunit of protein phosphatase 2A supports the tumorigenic and metastatic potential of pancreatic cancer cells by sustaining hyperactive oncogenic signaling. Cancer Research. PMID 26893480 DOI: 10.1158/0008-5472.Can-15-2119  0.346
2013 Wlodarchak N, Guo F, Satyshur KA, Jiang L, Jeffrey PD, Sun T, Stanevich V, Mumby MC, Xing Y. Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Research. 23: 931-46. PMID 23752926 DOI: 10.1038/Cr.2013.77  0.404
2010 Jayadeva G, Kurimchak A, Garriga J, Sotillo E, Davis AJ, Haines DS, Mumby M, Graña X. B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation. The Journal of Biological Chemistry. 285: 29863-73. PMID 20663872 DOI: 10.1074/Jbc.M110.162354  0.489
2008 Davis AJ, Yan Z, Martinez B, Mumby MC. Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit. The Journal of Biological Chemistry. 283: 16104-14. PMID 18397887 DOI: 10.1074/Jbc.M710313200  0.486
2007 Tsao CC, Nica AF, Kurinna SM, Jiffar T, Mumby M, Ruvolo PP. Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells. Cell Cycle (Georgetown, Tex.). 6: 2377-85. PMID 17700073 DOI: 10.4161/Cc.6.19.4737  0.338
2007 Mumby M. PP2A: Unveiling a Reluctant Tumor Suppressor Cell. 130: 21-24. PMID 17632053 DOI: 10.1016/J.Cell.2007.06.034  0.345
2007 Bielinski VA, Mumby MC. Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase. Experimental Cell Research. 313: 3117-26. PMID 17570358 DOI: 10.1016/J.Yexcr.2007.05.008  0.519
2007 Mumby M. The 3D structure of protein phosphatase 2A: new insights into a ubiquitous regulator of cell signaling. Acs Chemical Biology. 2: 99-103. PMID 17313179 DOI: 10.1021/Cb700021Z  0.391
2007 Fraser I, Liu W, Rebres R, Roach T, Zavzavadjian J, Santat L, Liu J, Wall E, Mumby M. The use of RNA interference to analyze protein phosphatase function in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 365: 261-86. PMID 17200568 DOI: 10.1385/1-59745-267-X:261  0.362
2007 Liu W, Silverstein AM, Shu H, Martinez B, Mumby MC. A functional genomics analysis of the B56 isoforms of Drosophila protein phosphatase 2A. Molecular & Cellular Proteomics : McP. 6: 319-32. PMID 17121811 DOI: 10.1074/Mcp.M600272-Mcp200  0.444
2006 Emrick MA, Lee T, Starkey PJ, Mumby MC, Resing KA, Ahn NG. The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 18101-6. PMID 17114285 DOI: 10.1073/pnas.0608849103  0.36
2006 Tang Z, Shu H, Qi W, Mahmood NA, Mumby MC, Yu H. PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Developmental Cell. 10: 575-85. PMID 16580887 DOI: 10.1016/J.Devcel.2006.03.010  0.55
2006 Esplin ED, Ramos P, Martinez B, Tomlinson GE, Mumby MC, Evans GA. The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function. Genes, Chromosomes & Cancer. 45: 182-90. PMID 16276521 DOI: 10.1002/Gcc.20284  0.306
2004 Shu H, Chen S, Bi Q, Mumby M, Brekken DL. Identification of Phosphoproteins and Their Phosphorylation Sites in the WEHI-231 B Lymphoma Cell Line Molecular & Cellular Proteomics. 3: 279-286. PMID 14729942 DOI: 10.1074/Mcp.D300003-Mcp200  0.493
2003 Silverstein AM, Mumby MC. Analysis of protein phosphatase function in Drosophila cells using RNA interference. Methods in Enzymology. 366: 361-72. PMID 14674261 DOI: 10.1016/S0076-6879(03)66027-1  0.43
2003 Brich J, Shie F, Howell BW, Li R, Tus K, Wakeland EK, Jin L, Mumby M, Churchill G, Herz J, Cooper JA. Genetic Modulation of Tau Phosphorylation in the Mouse The Journal of Neuroscience. 23: 187-192. DOI: 10.1523/Jneurosci.23-01-00187.2003  0.332
2002 Ruvolo PP, Clark W, Mumby M, Gao F, May WS. A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function. The Journal of Biological Chemistry. 277: 22847-52. PMID 11929874 DOI: 10.1074/Jbc.M201830200  0.405
2002 Silverstein AM, Barrow CA, Davis AJ, Mumby MC. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proceedings of the National Academy of Sciences of the United States of America. 99: 4221-6. PMID 11904383 DOI: 10.1073/Pnas.072071699  0.504
2001 Mumby M. A new role for protein methylation: switching partners at the phosphatase ball. Science Signaling. 2001. PMID 11752649 DOI: 10.1126/Stke.2001.79.Pe1  0.373
2000 Price NE, Mumby MC. Effects of regulatory subunits on the kinetics of protein phosphatase 2A. Biochemistry. 39: 11312-8. PMID 10985776 DOI: 10.1021/Bi0008478  0.395
2000 Yan Z, Fedorov SA, Mumby MC, Williams RS. PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells. Molecular and Cellular Biology. 20: 1021-9. PMID 10629059 DOI: 10.1128/Mcb.20.3.1021-1029.2000  0.432
1999 Price NE, Wadzinski B, Mumby MC. An anchoring factor targets protein phosphatase 2A to brain microtubules. Brain Research. Molecular Brain Research. 73: 68-77. PMID 10581399 DOI: 10.1016/S0169-328X(99)00237-5  0.447
1999 Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, Cooper JA, Herz J. Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron. 24: 481-9. PMID 10571241 DOI: 10.1016/S0896-6273(00)80861-2  0.36
1999 Yan Y, Mumby MC. Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein. PP2a regulates the activities of G(1) cyclin-dependent kinases. The Journal of Biological Chemistry. 274: 31917-24. PMID 10542219 DOI: 10.1074/Jbc.274.45.31917  0.499
1999 Sontag E, Nunbhakdi-Craig V, Lee G, Brandt R, Kamibayashi C, Kuret J, White CL, Mumby MC, Bloom GS. Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies. The Journal of Biological Chemistry. 274: 25490-8. PMID 10464280 DOI: 10.1074/Jbc.274.36.25490  0.378
1999 Price NE, Mumby MC. Brain protein serine/threonine phosphatases. Current Opinion in Neurobiology. 9: 336-42. PMID 10395578 DOI: 10.1016/S0959-4388(99)80049-X  0.376
1998 Mateer SC, Fedorov SA, Mumby MC. Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A. The Journal of Biological Chemistry. 273: 35339-46. PMID 9857076 DOI: 10.1074/Jbc.273.52.35339  0.334
1998 Deng X, Ito T, Carr B, Mumby M, May WS. Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A. Journal of Biological Chemistry. 273: 34157-34163. PMID 9852076 DOI: 10.1074/Jbc.273.51.34157  0.458
1998 Griswold-Prenner I, Kamibayashi C, Maruoka EM, Mumby MC, Derynck R. Physical and functional interactions between type I transforming growth factor beta receptors and Balpha, a WD-40 repeat subunit of phosphatase 2A. Molecular and Cellular Biology. 18: 6595-604. PMID 9774674 DOI: 10.1128/Mcb.18.11.6595  0.35
1998 Molloy SS, Thomas L, Kamibayashi C, Mumby MC, Thomas G. Regulation of endosome sorting by a specific PP2A isoform. The Journal of Cell Biology. 142: 1399-411. PMID 9744873 DOI: 10.1083/Jcb.142.6.1399  0.454
1998 Galadari S, Kishikawa K, Kamibayashi C, Mumby MC, Hannun YA. Purification and characterization of ceramide-activated protein phosphatases. Biochemistry. 37: 11232-8. PMID 9698369 DOI: 10.1021/bi980911  0.385
1997 Yan Y, Shay JW, Wright WE, Mumby MC. Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. The Journal of Biological Chemistry. 272: 15220-6. PMID 9182545 DOI: 10.1074/Jbc.272.24.15220  0.389
1997 Zhu T, Matsuzawa S, Mizuno Y, Kamibayashi C, Mumby MC, Andjelkovic N, Hemmings BA, Onoé K, Kikuchi K. The interconversion of protein phosphatase 2A between PP2A1 and PP2A0 during retinoic acid-induced granulocytic differentiation and a modification on the catalytic subunit in S phase of HL-60 cells. Archives of Biochemistry and Biophysics. 339: 210-7. PMID 9056251 DOI: 10.1006/Abbi.1996.9835  0.41
1996 Sontag E, Nunbhakdi-Craig V, Lee G, Bloom GS, Mumby MC. Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A. Neuron. 17: 1201-7. PMID 8982166 DOI: 10.1016/S0896-6273(00)80250-0  0.432
1996 Tehrani MA, Mumby MC, Kamibayashi C. Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle. The Journal of Biological Chemistry. 271: 5164-70. PMID 8617797 DOI: 10.1074/Jbc.271.9.5164  0.385
1995 Mumby M. Regulation by tumour antigens defines a role for PP2A in signal transduction. Seminars in Cancer Biology. 6: 229-237. PMID 8541518 DOI: 10.1006/Scbi.1995.0030  0.38
1995 Sontag E, Nunbhakdi-Craig V, Bloom GS, Mumby MC. A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. The Journal of Cell Biology. 128: 1131-44. PMID 7896877 DOI: 10.1083/Jcb.128.6.1131  0.425
1995 Omay SB, Ogasawara H, Toyoda H, Nakai K, Shima H, Nagao M, Mumby MC, Shiku H, Nishikawa M. Translocation of protein phosphatase 1 catalytic subunits during 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL-60 cells. Cancer Research. 55: 774-80. PMID 7850788 DOI: 10.11501/3100096  0.41
1994 Ruediger R, Hentz M, Fait J, Mumby M, Walter G. Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. Journal of Virology. 68: 123-129. PMID 8254721 DOI: 10.1128/Jvi.68.1.123-129.1994  0.4
1994 Sim AT, Ratcliffe E, Mumby MC, Villa-Moruzzi E, Rostas JA. Differential activities of protein phosphatase types 1 and 2A in cytosolic and particulate fractions from rat forebrain. Journal of Neurochemistry. 62: 1552-9. PMID 8133283 DOI: 10.1046/J.1471-4159.1994.62041552.X  0.379
1994 Nishikawa M, Omay SB, Toyoda H, Tawara I, Shima H, Nagao M, Hemmings BA, Mumby MC, Deguchi K. Expression of the catalytic and regulatory subunits of protein phosphatase type 2A may be differentially modulated during retinoic acid-induced granulocytic differentiation of HL-60 cells. Cancer Research. 54: 4879-84. PMID 8069853  0.327
1994 Frost JA, Alberts AS, Sontag E, Guan K, Mumby MC, Feramisco JR. Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. Molecular and Cellular Biology. 14: 6244-52. PMID 8065356 DOI: 10.1128/Mcb.14.9.6244  0.411
1993 Mumby MC, Walter G. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiological Reviews. 73: 673-99. PMID 8415923  0.355
1993 Walter G, Mumby M. Protein serine/threonine phosphatases and cell transformation. Biochimica Et Biophysica Acta. 1155: 207-226. PMID 8395218 DOI: 10.1016/0304-419X(93)90005-W  0.383
1993 Alberts AS, Deng T, Lin A, Meinkoth JL, Schönthal A, Mumby MC, Karin M, Feramisco JR. Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Molecular and Cellular Biology. 13: 2104-12. PMID 8384305 DOI: 10.1128/Mcb.13.4.2104  0.405
1993 Alberts AS, Thorburn AM, Shenolikar S, Mumby MC, Feramisco JR. Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. Proceedings of the National Academy of Sciences of the United States of America. 90: 388-92. PMID 8380637 DOI: 10.1073/Pnas.90.2.388  0.478
1993 Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell. 75: 887-97. PMID 8252625 DOI: 10.1016/0092-8674(93)90533-V  0.474
1992 Nomura M, Stull JT, Kamm KE, Mumby MC. Site-specific dephosphorylation of smooth muscle myosin light chain kinase by protein phosphatases 1 and 2A. Biochemistry. 31: 11915-20. PMID 1332778 DOI: 10.1021/Bi00162A034  0.444
1992 Kamibayashi C, Lickteig RL, Estes R, Walter G, Mumby MC. Expression of the A subunit of protein phosphatase 2A and characterization of its interactions with the catalytic and regulatory subunits. The Journal of Biological Chemistry. 267: 21864-72. PMID 1328247  0.314
1992 Kubota Y, Nomura M, Kamm KE, Mumby MC, Stull JT. GTP gamma S-dependent regulation of smooth muscle contractile elements. The American Journal of Physiology. 262: C405-10. PMID 1311501 DOI: 10.1152/Ajpcell.1992.262.2.C405  0.363
1991 Lee TH, Solomon MJ, Mumby MC, Kirschner MW. INH, a negative regulator of MPF, is a form of protein phosphatase 2A. Cell. 64: 415-23. PMID 1846321 DOI: 10.1016/0092-8674(91)90649-J  0.509
1991 Yang SI, Lickteig RL, Estes R, Rundell K, Walter G, Mumby MC. Control of protein phosphatase 2A by simian virus 40 small-t antigen. Molecular and Cellular Biology. 11: 1988-95. PMID 1706474 DOI: 10.1128/Mcb.11.4.1988  0.429
1991 Mumby MC, Walter G. Protein phosphatases and DNA tumor viruses: transformation through the back door? Cell Regulation. 2: 589-98. PMID 1663787  0.328
1991 Ruediger R, Hood JEVW, Mumby M, Walter G. Constant expression and activity of protein phosphatase 2A in synchronized cells. Molecular and Cellular Biology. 11: 4282-4285. PMID 1649390 DOI: 10.1128/Mcb.11.8.4282  0.464
1991 Kamibayashi C, Estes R, Slaughter C, Mumby MC. Subunit interactions control protein phosphatase 2A. Effects of limited proteolysis, N-ethylmaleimide, and heparin on the interaction of the B subunit. The Journal of Biological Chemistry. 266: 13251-60. PMID 1649186  0.354
1990 Fernandez A, Brautigan DL, Mumby M, Lamb NJC. Protein phosphatase type-1, not type-2A, modulates actin microfilament integrity and myosin light chain phosphorylation in living nonmuscle cells Journal of Cell Biology. 111: 103-112. PMID 2164027 DOI: 10.1083/Jcb.111.1.103  0.309
1990 Walter G, Ruediger R, Slaughter CA, Mumby M. Association of protein phosphatase 2A with polyoma virus medium tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 2521-2525. PMID 2157202 DOI: 10.1073/Pnas.87.7.2521  0.402
1989 Scott CW, Mumby MC. Autophosphorylation of rat liver type II cAMP-dependent protein kinase. Molecular Endocrinology (Baltimore, Md.). 3: 1815-22. PMID 2558304 DOI: 10.1210/Mend-3-11-1815  0.404
1988 Mumby MC, Scott CW. cAMP-dependent protein kinase regulatory subunit phosphorylation in intact cells. Methods in Enzymology. 159: 139-46. PMID 3412178 DOI: 10.1016/0076-6879(88)59014-6  0.467
1987 Green DD, Yang SI, Mumby MC. Molecular cloning and sequence analysis of the catalytic subunit of bovine type 2A protein phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 84: 4880-4. PMID 3037526 DOI: 10.1073/Pnas.84.14.4880  0.348
1987 Johnson GL, Brautigan DL, Shriner C, Jaspers S, Arino J, Mole JE, Miller TB, Mumby MC. Sequence homologies between type 1 and type 2A protein phosphatases. Molecular Endocrinology (Baltimore, Md.). 1: 745-8. PMID 2856400 DOI: 10.1210/Mend-1-10-745  0.334
1986 Lawrence JC, Hiken JF, Inkster M, Scott CW, Mumby MC. Insulin stimulates the generation of an adipocyte phosphoprotein that is isolated with a monoclonal antibody against the regulatory subunit of bovine heart cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 3649-53. PMID 2424009 DOI: 10.1073/Pnas.83.11.3649  0.388
1985 Scott CW, Mumby MC. Phosphorylation of type II regulatory subunit of cAMP-dependent protein kinase in intact smooth muscle. The Journal of Biological Chemistry. 260: 2274-80. PMID 2982813  0.336
1984 Scott CW, Mumby MC. Regulation of the phosphorylation state of the type II regulatory subunit of cAMP dependent protein kinase in vivo Federation Proceedings. 43: no. 3083.  0.355
1982 Doherty PJ, Tsao J, Schimmer BP, Mumby MC, Beavo JA. Alteration of the regulatory subunit of type 1 cAMP-dependent protein kinase in mutant Y1 adrenal cells resistant to 8-bromoadenosine 3':5'-monophosphate. The Journal of Biological Chemistry. 257: 5877-83. PMID 6279618  0.344
1980 Mumby M, Traugh JA. Multiple forms of phosphoprotein phosphatase from rabbit reticulocytes Bba - Enzymology. 611: 342-350. PMID 6243990 DOI: 10.1016/0005-2744(80)90070-4  0.56
1979 Mumby M, Traugh JA. Dephosphorylation of translational initiation factors and 40S ribosomal subunits by phosphoprotein phosphatases from rabbit reticulocytes Biochemistry. 18: 4548-4556. PMID 227442 DOI: 10.1021/Bi00588A015  0.579
1979 Mumby M, Traugh JA. [47] Dephosphorylation of translational components of phosphoprotein phosphatases from reticulocytes Methods in Enzymology. 60: 522-534. DOI: 10.1016/S0076-6879(79)60049-6  0.547
1975 Lightfoot HN, Mumby M, Traugh JA. Dephosphorylation of 40S ribosomal subunits by phosphoprotein phosphatase activity from rabbit reticulocytes Biochemical and Biophysical Research Communications. 66: 1141-1146. PMID 172072 DOI: 10.1016/0006-291X(75)90477-5  0.634
1973 Trauch JA, Mumby M, Traut RR. Phosphorylation of ribosomal proteins by substrate-specific protein kinases from rabbit reticulocytes. Proceedings of the National Academy of Sciences of the United States of America. 70: 373-6. PMID 4346887 DOI: 10.1073/Pnas.70.2.373  0.498
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