Miriam H. Meisler

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Genetics, Neuroscience Biology
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"Miriam Meisler"
Cross-listing: Neurotree

Children

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Nicholas W. Plummer grad student 1998 University of Michigan (Neurotree)
David A. Buchner grad student 2003 University of Michigan (Neurotree)
Stephen I. Levin grad student 2004 University of Michigan (Neurotree)
Bryan T. MacDonald grad student 2004 University of Michigan (Neurotree)
Valerie L. Drews grad student 2005 University of Michigan (Neurotree)
Cole J. Ferguson grad student 2011 University of Michigan (Neurotree)
Andrew P. Escayg post-doc (Cell Biology Tree)
David C. Kohrman post-doc (Neurotree)
Leslie Sprunger post-doc 1995-2000 University of Michigan (Neurotree)
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Publications

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Hill SF, Yu W, Ziobro J, et al. (2023) Long-term downregulation of the sodium channel gene Scn8a is therapeutic in mouse models of SCN8A epilepsy. Annals of Neurology
Hill SF, Jafar-Nejad P, Rigo F, et al. (2023) Reduction of is therapeutic in mouse models of and epilepsy. Frontiers in Neuroscience. 17: 1282201
Cao X, Lenk GM, Meisler MH. (2023) Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes Fig4 and Pip4k2c. G3 (Bethesda, Md.)
Hill SF, Ziobro J, Jafar-Nejad P, et al. (2022) Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2. Epilepsia
Yu W, Mulligan MK, Williams RW, et al. (2022) Correction of the hypomorphic splice site variant in mouse strain C57BL/6J modifies the severity of encephalopathy. Hgg Advances. 3: 100064
Yu W, Smolen CE, Hill SF, et al. (2021) Spontaneous seizures and elevated seizure susceptibility in response to somatic mutation of sodium channel Scn8a in the mouse. Human Molecular Genetics
Meisler MH, Hill SF, Yu W. (2021) Sodium channelopathies in neurodevelopmental disorders. Nature Reviews. Neuroscience
Lenk GM, Jafar-Nejad P, Hill SF, et al. (2020) Scn8a antisense oligonucleotide is protective in mouse models of SCN8A Encephalopathy and Dravet Syndrome. Annals of Neurology
Du J, Simmons S, Brunklaus A, et al. (2019) Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders. European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society
Meisler MH. (2019) SCN8A encephalopathy: Mechanisms and models. Epilepsia. 60: S86-S91
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