Scott Allen Armstrong
Affiliations: | Biology, Molecular and Cellular | Harvard University, Cambridge, MA, United States |
Area:
General Biology, Molecular Biology, Biochemistry, OncologyWebsite:
https://hsci.harvard.edu/people/scott-armstrong-md-phdGoogle:
"Scott Allen Armstrong"Bio:
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Parents
Sign in to add mentorMichael Stuart Brown | grad student | 1994 | UT Southwestern | |
(Molecular and biochemical characterization of Rab geranylgeranyl transferase.) | ||||
Joseph L. Goldstein | grad student | 1994 | UT Southwestern |
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Publications
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Gu H, Chen C, Hou ZS, et al. (2024) PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway. Blood |
Tubío-Santamaría N, Jayavelu AK, Schnoeder TM, et al. (2023) Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia. Molecular Cancer. 22: 196 |
Issa GC, Aldoss I, DiPersio J, et al. (2023) The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia. Nature |
Uckelmann HJ, Haarer EL, Takeda R, et al. (2022) Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia. Cancer Discovery |
Soto-Feliciano YM, Sanchez-Rivera FJ, Perner F, et al. (2022) A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition. Cancer Discovery |
Aubrey BJ, Cutler JA, Bourgeois W, et al. (2022) IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature Cancer |
Heikamp EB, Henrich JA, Perner F, et al. (2021) The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood |
Perner F, Schnoeder TM, Xiong Y, et al. (2021) YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. Leukemia |
Cai SF, Chu SH, Goldberg AD, et al. (2020) Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition. Cancer Discovery |
Dzama MM, Steiner M, Rausch J, et al. (2020) Synergistic Targeting of FLT3 Mutations in AML via Combined Menin-MLL and FLT3 Inhibition. Blood |