Thanh G. Sargent, Ph.D.

Affiliations: 
2000 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Molecular Biology, Genetics, Cell Biology
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"Thanh Sargent"

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Joyce A. Lloyd grad student 2000 VCU
 (The roles of HS3 of the LCR and the gamma-globin TATA, CACCC, and SSE elements in competitive inhibition of beta-globin gene expression in tissue culture and in transgenic mice.)
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Publications

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Basu P, Lung TK, Lemsaddek W, et al. (2007) EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis. Blood. 110: 3417-25
Basu P, Sargent TG, Redmond LC, et al. (2004) Evolutionary conservation of KLF transcription factors and functional conservation of human gamma-globin gene regulation in chicken. Genomics. 84: 311-9
Singal R, Wang SZ, Sargent T, et al. (2002) Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. The Journal of Biological Chemistry. 277: 1897-905
Sargent TG, Lloyd JA. (2001) The human gamma-globin TATA and CACCC elements have key, distinct roles in suppressing beta-globin gene expression in embryonic/fetal development. The Journal of Biological Chemistry. 276: 41817-24
Sargent TG, Buller AM, Teachey DT, et al. (1999) The gamma-globin promoter has a major role in competitive inhibition of beta-globin gene expression in early erythroid development. Dna and Cell Biology. 18: 293-303
Sargent TG, DuBois CC, Buller AM, et al. (1999) The roles of 5'-HS2, 5'-HS3, and the gamma-globin TATA, CACCC, and stage selector elements in suppression of beta-globin expression in early development. The Journal of Biological Chemistry. 274: 11229-36
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