Jianfu Chen, Ph.D.
Affiliations: | 2008 | Cell & Developmental Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Cell BiologyGoogle:
"Jianfu Chen"Parents
Sign in to add mentorLee Niswander | grad student | University of Colorado, Denver (Neurotree) | ||
Da-Zhi Wang | grad student | 2008 | UNC Chapel Hill | |
(MicroRNA function in muscle development.) |
Children
Sign in to add traineeStephanie Herrlinger | grad student | 2013-2018 | University of Southern California Keck School of Medicine (Neurotree) |
Qiang(Eric) Shao | post-doc | 2015- | (Neurotree) |
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Publications
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Zhang W, Ma L, Yang M, et al. (2020) Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes & Development |
Liang C, Shao Q, Zhang W, et al. (2020) Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Human Molecular Genetics |
Shao Q, Yang M, Liang C, et al. (2019) and mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy |
Liang C, Shao Q, Zhang W, et al. (2019) Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Human Molecular Genetics |
Zhang W, Yang SL, Yang M, et al. (2019) Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nature Communications. 10: 2612 |
Herrlinger S, Shao Q, Yang M, et al. (2019) Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice. Development (Cambridge, England) |
Gao F, Kataoka M, Liu N, et al. (2019) Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction. Nature Communications. 10: 1802 |
Shao Q, Liang C, Chang Q, et al. (2019) C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner. Acta Neuropathologica Communications. 7: 32 |
Herrlinger SA, Shao Q, Ma L, et al. (2018) Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult. Journal of Visualized Experiments : Jove |
Dong K, Guo X, Chen W, et al. (2018) Mesenchyme Homeobox 1 mediates transforming growth factor-β (TGF-β)-induced smooth muscle cell differentiation from mouse mesenchymal progenitors. The Journal of Biological Chemistry |