Ronald L. Chandler, Ph.D.

Affiliations: 
2007 Vanderbilt University, Nashville, TN 
Area:
Molecular Biology, Genetics
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"Ronald Chandler"

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Douglas P. Mortlock grad student 2007 Vanderbilt
 (Regulation of BMP2 transcription in bone.)
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Publications

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Kamiya N, Shafer S, Oxendine I, et al. (2013) Acute BMP2 upregulation following induction of ischemic osteonecrosis in immature femoral head. Bone. 53: 239-47
Jiang S, Chandler RL, Fritz DT, et al. (2010) Repressive BMP2 gene regulatory elements near the BMP2 promoter. Biochemical and Biophysical Research Communications. 392: 124-8
Anderson L, Lowery JW, Frank DB, et al. (2010) Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R833-42
Chandler KJ, Chandler RL, Mortlock DP. (2009) Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter. Developmental Biology. 327: 590-602
Luppen CA, Chandler RL, Noh T, et al. (2008) BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization. Growth Factors (Chur, Switzerland). 26: 226-37
Chandler KJ, Chandler RL, Broeckelmann EM, et al. (2007) Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 693-708
Spagnoli A, O'Rear L, Chandler RL, et al. (2007) TGF-beta signaling is essential for joint morphogenesis. The Journal of Cell Biology. 177: 1105-17
Chandler RL, Chandler KJ, McFarland KA, et al. (2007) Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter. Molecular and Cellular Biology. 27: 2934-51
Deal KK, Cantrell VA, Chandler RL, et al. (2006) Distant regulatory elements in a Sox10-βGEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues Developmental Dynamics. 235: 1413-1432
Chandler KJ, Chandler RL, Mortlock DP. (2006) Exploring the role of long-range evolutionarily conserved regions (ECRs) flanking Bmp4 Developmental Biology. 295: 369
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