Merlin N. Gnanapragasam, Ph.D.

Affiliations: 
2010 Human Genetics Virginia Commonwealth University, Richmond, VA, United States 
Area:
Molecular Biology, Genetics
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"Merlin Gnanapragasam"

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Gordon D. Ginder grad student 2010 VCU
 (The Role of Methyl CpG Binding Domain Protein 2 (MBD2) in the Regulation of Embryonic and Fetal beta-type Globin Genes.)
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Publications

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Elagooz R, Dhara AR, Gott RM, et al. (2022) PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin. Blood Advances
Mukherjee K, Xue L, Planutis A, et al. (2021) EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis. Elife. 10
Gnanapragasam MN, Crispino JD, Ali AM, et al. (2018) Survey and evaluation of mutations in the human KLF1 transcription unit. Scientific Reports. 8: 6587
Gnanapragasam MN, Bieker JJ. (2017) Orchestration of late events in erythropoiesis by KLF1/EKLF. Current Opinion in Hematology
Gnanapragasam MN, McGrath KE, Catherman S, et al. (2016) EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation. Blood
Liang R, Campreciós G, Kou Y, et al. (2015) A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. Plos Genetics. 11: e1005526
Yien YY, Gnanapragasam MN, Gupta R, et al. (2015) Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues. Experimental Hematology. 43: 65-70
Xue L, Galdass M, Gnanapragasam MN, et al. (2014) Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche. Development (Cambridge, England). 141: 2245-54
Jaffray JA, Mitchell WB, Gnanapragasam MN, et al. (2013) Erythroid transcription factor EKLF/KLF1 mutation causing congenital dyserythropoietic anemia type IV in a patient of Taiwanese origin: review of all reported cases and development of a clinical diagnostic paradigm. Blood Cells, Molecules & Diseases. 51: 71-5
Amaya M, Desai M, Gnanapragasam MN, et al. (2013) Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells. Blood. 121: 3493-501
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