Jean-Michel Heard, PhD

Affiliations: 
Institut Pasteur, Paris, Paris, France 
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"Jean-Michel Heard"
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Tardieu M, Zérah M, Husson B, et al. (2014) Intracerebral administration of adeno-associated viral vector serotype rh.10 carrying human SGSH and SUMF1 cDNAs in children with mucopolysaccharidosis type IIIA disease: results of a phase I/II trial. Human Gene Therapy. 25: 506-16
Héron B, Mikaeloff Y, Froissart R, et al. (2011) Incidence and natural history of mucopolysaccharidosis type III in France and comparison with United Kingdom and Greece. American Journal of Medical Genetics. Part A. 155: 58-68
Ellinwood NM, Ausseil J, Desmaris N, et al. (2011) Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 251-9
Ciron C, Cressant A, Roux F, et al. (2009) Human alpha-iduronidase gene transfer mediated by adeno-associated virus types 1, 2, and 5 in the brain of nonhuman primates: vector diffusion and biodistribution. Human Gene Therapy. 20: 350-60
Ausseil J, Desmaris N, Bigou S, et al. (2008) Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice. Plos One. 3: e2296
Ciron C, Desmaris N, Colle MA, et al. (2006) Gene therapy of the brain in the dog model of Hurler's syndrome. Annals of Neurology. 60: 204-13
Chen F, Vitry S, Hocquemiller M, et al. (2006) alpha-L-Iduronidase transport in neurites. Molecular Genetics and Metabolism. 87: 349-58
Favre D, Blouin V, Provost N, et al. (2002) Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus. Journal of Virology. 76: 11605-11
Sol-Foulon N, Moris A, Nobile C, et al. (2002) HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread. Immunity. 16: 145-55
Maréchal V, Prevost MC, Petit C, et al. (2001) Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis. Journal of Virology. 75: 11166-77
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