John Gustin, Ph.D.
Affiliations: | 2009 | Johns Hopkins University, Baltimore, MD |
Area:
Chemical Engineering, Molecular BiologyGoogle:
"John Gustin"Parents
Sign in to add mentorBen Ho Park | grad student | 2009 | Johns Hopkins | |
(Characterization and targeting of oncogenic PIK3CA signaling.) |
BETA: Related publications
See more...
Publications
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
Gustin JP, Miller J, Farag M, et al. (2017) GATA3 frameshift mutation promotes tumor growth in human luminal breast cancer cells and induces transcriptional changes seen in primary GATA3 mutant breast cancers. Oncotarget. 8: 103415-103427 |
Beaver JA, Gustin JP, Yi KH, et al. (2013) PIK3CA and AKT1 mutations have distinct effects on sensitivity to targeted pathway inhibitors in an isogenic luminal breast cancer model system. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5413-22 |
Wang GM, Wong HY, Konishi H, et al. (2013) Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. Cancer Research. 73: 3248-61 |
Yi KH, Axtmayer J, Gustin JP, et al. (2013) Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine. Oncotarget. 4: 29-34 |
Garay JP, Karakas B, Abukhdeir AM, et al. (2012) The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation. Breast Cancer Research : Bcr. 14: R27 |
Konishi H, Mohseni M, Tamaki A, et al. (2011) Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 17773-8 |
Higgins MJ, Beaver JA, Wong HY, et al. (2011) PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells. Cancer Biology & Therapy. 11: 358-67 |
Lauring J, Cosgrove DP, Fontana S, et al. (2010) Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations Oncogene. 29: 2337-2345 |
Higgins MJ, Abukhdeir AM, Gustin J, et al. (2009) Preclinical study of lithium sensitivity in human breast PTEN knock out cell lines. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e14641 |
Gustin JP, Karakas B, Weiss MB, et al. (2009) Knockin of mutant PIK3CA activates multiple oncogenic pathways. Proceedings of the National Academy of Sciences of the United States of America. 106: 2835-40 |