Ton N.M. Schumacher
Affiliations: | 1996- | Netherlands Cancer Institute |
Website:
https://scienceforlife.sites.uu.nl/keynote-speakers/ton-schumacher/Google:
"Ton Schumacher"Bio:
Parents
Sign in to add mentor| Hidde L. Ploegh | grad student | 1992 | VU Amsterdam (Chemistry Tree) | |
| (Interactions of MHC class I molecules with antigenic peptides) | ||||
| Peter S. Kim | post-doc | 1994-1996 | Whitehead Institute for Biomedical Research (Chemistry Tree) | |
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Publications
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| Kuilman T, Schrikkema DS, Gadiot J, et al. (2025) Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies. Nature Communications. 16: 649 |
| Chen XT, Leisegang M, Gavvovidis I, et al. (2024) Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system. Frontiers in Immunology. 15: 1524629 |
| Nederlof I, Isaeva OI, de Graaf M, et al. (2024) Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial. Nature Medicine |
| Richterich CA, Logtenberg MEW, Jansen MJH, et al. (2024) ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo. Journal of Immunology (Baltimore, Md. : 1950) |
| Sultan H, Takeuchi Y, Ward JP, et al. (2024) Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature |
| Moravec Z, Zhao Y, Voogd R, et al. (2024) Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening. Nature Biotechnology |
| Hoekstra ME, Slagter M, Urbanus J, et al. (2024) Distinct spatiotemporal dynamics of CD8 T cell-derived cytokines in the tumor microenvironment. Cancer Cell. 42: 157-167.e9 |
| Kenski JCN, Huang X, Vredevoogd DW, et al. (2023) An adverse tumor-protective effect of IDO1 inhibition. Cell Reports. Medicine. 4: 100941 |
| de Vries NL, van de Haar J, Veninga V, et al. (2023) γδ T cells are effectors of immunotherapy in cancers with HLA class I defects. Nature. 613: 743-750 |
| Cattaneo CM, Battaglia T, Urbanus J, et al. (2023) Identification of patient-specific CD4 and CD8 T cell neoantigens through HLA-unbiased genetic screens. Nature Biotechnology |