Warren D. Kruger, PhD

Affiliations: 
1995- Fox Chase Cancer Center 
Area:
Human Genetics and Disease
Website:
http://www.fccc.edu/research/pid/kruger/index.html
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"Warren Kruger"
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Parents

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Ira Herskowitz grad student 1986-1991 UCSF
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Publications

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Cal-Kayitmazbatir S, Kulkoyluoglu-Cotul E, Growe J, et al. (2020) CRY1-CBS binding regulates circadian clock function and metabolism. The Febs Journal
Gupta S, Gallego-Villar L, Wang L, et al. (2019) Analysis of the Qatari R336C Cystathionine β-Synthase Protein in Mice. Journal of Inherited Metabolic Disease
Lee HO, Gallego-Villar L, Grisch-Chan HM, et al. (2019) Treatment of CBS deficiency in mice using a minicircle-based naked DNA vector. Human Gene Therapy
Ismail HM, Krishnamoorthy N, Al-Dewik N, et al. (2018) In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies. Human Mutation
Gupta S, Kelow S, Wang L, et al. (2018) Mouse modeling and structural analysis of the p.G307S mutation in human cystathionine β-synthase () reveal effects on CBS activity but not stability. The Journal of Biological Chemistry
Lee HO, Wang L, Kuo YM, et al. (2018) S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice. Molecular Genetics and Metabolism Reports. 15: 15-21
Tang B, Lee HO, An SS, et al. (2018) Specific targeting of MTAP-deleted tumors with a combination of 2'-fluoroadenine and 5'-methylthioadenosine. Cancer Research
Majtan T, Jones W, Krijt J, et al. (2017) Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria. Molecular Therapy : the Journal of the American Society of Gene Therapy
Gallego-Villar L, Hannibal L, Häberle J, et al. (2017) Cysteamine revisited: repair of arginine to cysteine mutations. Journal of Inherited Metabolic Disease
Kruger WD. (2017) Cystathionine β-synthase deficiency: Of mice and men. Molecular Genetics and Metabolism
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