Jeffrey M. Leiden - Publications

Affiliations: 
University of Chicago, Chicago, IL 

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 19: 863-75. PMID 14670303 DOI: 10.1016/S1074-7613(03)00328-5  0.397
2003 Hettmann T, Opferman JT, Leiden JM, Ashton-Rickardt PG. A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells. Immunology Letters. 85: 297-300. PMID 12663146 DOI: 10.1016/S0165-2478(02)00260-2  0.365
2002 Eckhart AD, Fentzke RC, Lepore J, Lang R, Lin H, Lefkowitz RJ, Koch WJ, Leiden JM. Inhibition of betaARK1 restores impaired biochemical beta-adrenergic receptor responsiveness but does not rescue CREB(A133) induced cardiomyopathy. Journal of Molecular and Cellular Cardiology. 34: 669-77. PMID 12054854 DOI: 10.1006/jmcc.2002.2007  0.329
2001 Buckley AF, Kuo CT, Leiden JM. Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. Nature Immunology. 2: 698-704. PMID 11477405 DOI: 10.1038/90633  0.614
2001 Williams KL, Nanda I, Lyons GE, Kuo CT, Schmid M, Leiden JM, Kaplan MH, Taparowsky EJ. Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. European Journal of Immunology. 31: 1620-7. PMID 11466704 DOI: 10.1002/1521-4141(200105)31:5<1620::Aid-Immu1620>3.0.Co;2-3  0.615
2001 Moawad J, Meyerson SL, Refai D, Skelly CL, Leiden JM, Schwartz LB. Adenoviral-mediated gene transfer in human and animal vein grafts using clinically relevant exposure times, pressures, and viral concentrations. Annals of Vascular Surgery. 15: 367-73. PMID 11414089 DOI: 10.1007/s100160010081  0.306
2001 Huggins GS, Bacani CJ, Boltax J, Aikawa R, Leiden JM. Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter. The Journal of Biological Chemistry. 276: 28029-36. PMID 11382775 DOI: 10.1074/Jbc.M103577200  0.402
2001 Kentish JC, McCloskey DT, Layland J, Palmer S, Leiden JM, Martin AF, Solaro RJ. Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle. Circulation Research. 88: 1059-65. PMID 11375276 DOI: 10.1161/Hh1001.091640  0.304
2001 Fentzke RC, Korcarz CE, Shroff SG, Lin H, Leiden JM, Lang RM. The left ventricular stress-velocity relation in transgenic mice expressing a dominant negative CREB transgene in the heart. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 14: 209-18. PMID 11241017 DOI: 10.1067/Mje.2001.111473  0.307
2000 Hettmann T, Leiden JM. NF-kappa B is required for the positive selection of CD8+ thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 165: 5004-10. PMID 11046028 DOI: 10.4049/Jimmunol.165.9.5004  0.359
2000 Tong Q, Dalgin G, Xu H, Ting CN, Leiden JM, Hotamisligil GS. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science (New York, N.Y.). 290: 134-8. PMID 11021798 DOI: 10.1126/Science.290.5489.134  0.375
2000 Marshall DJ, Palasis M, Lepore JJ, Leiden JM. Biocompatibility of cardiovascular gene delivery catheters with adenovirus vectors: an important determinant of the efficiency of cardiovascular gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 423-9. PMID 10933963 DOI: 10.1006/mthe.2000.0059  0.312
2000 Svensson EC, Huggins GS, Lin H, Clendenin C, Jiang F, Tufts R, Dardik FB, Leiden JM. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nature Genetics. 25: 353-6. PMID 10888889 DOI: 10.1038/77146  0.326
2000 Hettmann T, Barton K, Leiden JM. Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor. Developmental Biology. 222: 110-23. PMID 10885750 DOI: 10.1006/dbio.2000.9699  0.422
2000 Leiden JM. Human gene therapy: the good, the bad, and the ugly. Circulation Research. 86: 923-5. PMID 10807862 DOI: 10.1161/01.Res.86.9.923  0.333
2000 Svensson EC, Huggins GS, Dardik FB, Polk CE, Leiden JM. A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription. The Journal of Biological Chemistry. 275: 20762-9. PMID 10801815 DOI: 10.1074/Jbc.M001522200  0.352
2000 Morrisey EE, Musco S, Chen MY, Lu MM, Leiden JM, Parmacek MS. The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm. The Journal of Biological Chemistry. 275: 19949-54. PMID 10779506 DOI: 10.1074/Jbc.M001331200  0.455
2000 Walunas TL, Wang B, Wang CR, Leiden JM. Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 2857-60. PMID 10706669 DOI: 10.4049/jimmunol.164.6.2857  0.423
1999 Schober SL, Kuo CT, Schluns KS, Lefrancois L, Leiden JM, Jameson SC. Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 163: 3662-7. PMID 10490960  0.552
1999 Macejak DG, Lin H, Webb S, Chase J, Jensen K, Jarvis TC, Leiden JM, Couture L. Adenovirus-mediated expression of a ribozyme to c-myb mRNA inhibits smooth muscle cell proliferation and neointima formation in vivo. Journal of Virology. 73: 7745-51. PMID 10438864 DOI: 10.1128/Jvi.73.9.7745-7751.1999  0.348
1999 Kuo CT, Leiden JM. Transcriptional regulation of T lymphocyte development and function. Annual Review of Immunology. 17: 149-87. PMID 10358756 DOI: 10.1146/annurev.immunol.17.1.149  0.612
1999 Schwartz LB, Moawad J, Svensson EC, Tufts RL, Meyerson SL, Baunoch D, Leiden JM. Adenoviral-mediated gene transfer of a constitutively active form of the retinoblastoma gene product attenuates neointimal thickening in experimental vein grafts. Journal of Vascular Surgery. 29: 874-81; discussion 8. PMID 10231639 DOI: 10.1016/S0741-5214(99)70215-6  0.321
1999 Fentzke RC, Buck SH, Patel JR, Lin H, Wolska BM, Stojanovic MO, Martin AF, Solaro RJ, Moss RL, Leiden JM. Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart. The Journal of Physiology. 517: 143-57. PMID 10226156 DOI: 10.1111/J.1469-7793.1999.0143Z.X  0.329
1999 Klinman DM, Conover J, Leiden JM, Rosenberg AS, Sechler JM. Safe and effective regulation of hematocrit by gene gun administration of an erythropoietin-encoding DNA plasmid. Human Gene Therapy. 10: 659-65. PMID 10094209 DOI: 10.1089/10430349950018733  0.378
1999 Leiden JM. Beating the odds: a cardiomyocyte cell line at last. The Journal of Clinical Investigation. 103: 591-2. PMID 10074473 DOI: 10.1172/JCI6471  0.418
1999 Mor-Avi V, Korcarz C, Fentzke RC, Lin H, Leiden JM, Lang RM. Quantitative evaluation of left ventricular function in a TransgenicMouse model of dilated cardiomyopathy with 2-dimensional contrast echocardiography. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 12: 209-14. PMID 10070185 DOI: 10.1016/S0894-7317(99)70137-9  0.306
1999 Svensson EC, Tufts RL, Polk CE, Leiden JM. Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 956-61. PMID 9927675 DOI: 10.1073/Pnas.96.3.956  0.429
1999 Svensson EC, Marshall DJ, Woodard K, Lin H, Jiang F, Chu L, Leiden JM. Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors. Circulation. 99: 201-5. PMID 9892583 DOI: 10.1161/01.Cir.99.2.201  0.366
1999 Hettmann T, DiDonato J, Karin M, Leiden JM. An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. The Journal of Experimental Medicine. 189: 145-58. PMID 9874571 DOI: 10.1084/jem.189.1.145  0.386
1998 Bassuk AG, Barton KP, Anandappa RT, Lu MM, Leiden JM. Expression pattern of the Ets-related transcription factor Elf-1. Molecular Medicine (Cambridge, Mass.). 4: 392-401. PMID 10780882 DOI: 10.1007/Bf03401746  0.477
1998 Barton K, Muthusamy N, Fischer C, Ting CN, Walunas TL, Lanier LL, Leiden JM. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity. 9: 555-63. PMID 9806641 DOI: 10.1016/S1074-7613(00)80638-X  0.37
1998 Muthusamy N, Leiden JM. A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement. The Journal of Biological Chemistry. 273: 22841-7. PMID 9712919 DOI: 10.1074/jbc.273.35.22841  0.366
1998 Marshall DJ, Leiden JM. Recent advances in skeletal-muscle-based gene therapy. Current Opinion in Genetics & Development. 8: 360-5. PMID 9691001 DOI: 10.1016/S0959-437X(98)80094-4  0.326
1998 Lin H, Rathmell JC, Gray GS, Thompson CB, Leiden JM, Alegre ML. Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. The Journal of Experimental Medicine. 188: 199-204. PMID 9653096 DOI: 10.1084/Jem.188.1.199  0.337
1998 Fentzke RC, Korcarz CE, Lang RM, Lin H, Leiden JM. Dilated cardiomyopathy in transgenic mice expressing a dominant-negative CREB transcription factor in the heart. The Journal of Clinical Investigation. 101: 2415-26. PMID 9616213 DOI: 10.1172/JCI2950  0.366
1997 Kuo CT, Veselits ML, Leiden JM. LKLF and FasL expression: correctiona and clarification. Science (New York, N.Y.). 278: 788-9. PMID 9381186 DOI: 10.1126/Science.278.5339.785E  0.591
1997 Kuo CT, Veselits ML, Barton KP, Lu MM, Clendenin C, Leiden JM. The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes & Development. 11: 2996-3006. PMID 9367982 DOI: 10.1101/Gad.11.22.2996  0.554
1997 Kuo CT, Veselits ML, Leiden JM. LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science (New York, N.Y.). 277: 1986-90. PMID 9302292 DOI: 10.1126/science.277.5334.1986  0.603
1997 Kim S, Lin H, Barr E, Chu L, Leiden JM, Parmacek MS. Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo. The Journal of Clinical Investigation. 100: 1006-14. PMID 9276717 DOI: 10.1172/Jci119611  0.454
1997 Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes & Development. 11: 1048-60. PMID 9136932 DOI: 10.1101/Gad.11.8.1048  0.556
1997 Bassuk AG, Leiden JM. The role of Ets transcription factors in the development and function of the mammalian immune system. Advances in Immunology. 64: 65-104. PMID 9100980 DOI: 10.1016/S0065-2776(08)60887-1  0.367
1997 Bassuk AG, Anandappa RT, Leiden JM. Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells. Journal of Virology. 71: 3563-73. PMID 9094628 DOI: 10.1128/Jvi.71.5.3563-3573.1997  0.379
1996 Ting CN, Olson MC, Barton KP, Leiden JM. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 384: 474-8. PMID 8945476 DOI: 10.1038/384474a0  0.48
1996 Tripathy SK, Svensson EC, Black HB, Goldwasser E, Margalith M, Hobart PM, Leiden JM. Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. Proceedings of the National Academy of Sciences of the United States of America. 93: 10876-80. PMID 8855275 DOI: 10.1073/Pnas.93.20.10876  0.332
1996 Tripathy SK, Black HB, Goldwasser E, Leiden JM. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nature Medicine. 2: 545-50. PMID 8616713 DOI: 10.1038/Nm0596-545  0.36
1996 Barton K, Muthusamy N, Chanyangam M, Fischer C, Clendenin C, Leiden JM. Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature. 379: 81-5. PMID 8538746 DOI: 10.1038/379081a0  0.483
1995 Soudais C, Bielinska M, Heikinheimo M, MacArthur CA, Narita N, Saffitz JE, Simon MC, Leiden JM, Wilson DB. Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development (Cambridge, England). 121: 3877-88. PMID 8582296  0.315
1995 Ip HS, Wilson DB, Heikinheimo M, Leiden JM, Parmacek MS. The GATA-4 transcription factor transactivates the cardiac-specific troponin C promoter-enhancer in non-muscle cells. Advances in Experimental Medicine and Biology. 382: 117-24. PMID 8540389  0.331
1995 Chang MW, Barr E, Seltzer J, Jiang YQ, Nabel GJ, Nabel EG, Parmacek MS, Leiden JM. Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science (New York, N.Y.). 267: 518-22. PMID 7824950 DOI: 10.1126/science.7824950  0.331
1995 Bassuk AG, Leiden JM. A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Immunity. 3: 223-37. PMID 7648395 DOI: 10.1016/1074-7613(95)90092-6  0.364
1995 Chang MW, Barr E, Lu MM, Barton K, Leiden JM. Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. The Journal of Clinical Investigation. 96: 2260-8. PMID 7593612 DOI: 10.1172/JCI118281  0.348
1995 Muthusamy N, Barton K, Leiden JM. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature. 377: 639-42. PMID 7566177 DOI: 10.1038/377639a0  0.452
1994 Barr E, Leiden JM. Somatic gene therapy for cardiovascular disease Recent advances. Trends in Cardiovascular Medicine. 4: 57-63. PMID 21244896 DOI: 10.1016/1050-1738(94)90010-8  0.342
1994 Wang CY, Bassuk AG, Boise LH, Thompson CB, Bravo R, Leiden JM. Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors. Molecular and Cellular Biology. 14: 1153-9. PMID 8289796  0.382
1994 Parmacek MS, Ip HS, Jung F, Shen T, Martin JF, Vora AJ, Olson EN, Leiden JM. A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle. Molecular and Cellular Biology. 14: 1870-85. PMID 8114720 DOI: 10.1128/mcb.14.3.1870-1885.1994  0.346
1994 Tripathy SK, Goldwasser E, Lu MM, Barr E, Leiden JM. Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus. Proceedings of the National Academy of Sciences of the United States of America. 91: 11557-61. PMID 7972101 DOI: 10.1073/Pnas.91.24.11557  0.331
1994 Ip HS, Wilson DB, Heikinheimo M, Tang Z, Ting CN, Simon MC, Leiden JM, Parmacek MS. The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Molecular and Cellular Biology. 14: 7517-26. PMID 7935467 DOI: 10.1128/MCB.14.11.7517  0.438
1994 Wurster AL, Siu G, Leiden JM, Hedrick SM. Elf-1 binds to a critical element in a second CD4 enhancer. Molecular and Cellular Biology. 14: 6452-63. PMID 7935370 DOI: 10.1128/Mcb.14.10.6452  0.322
1994 Leiden JM, Thompson CB. Transcriptional regulation of T-cell genes during T-cell development. Current Opinion in Immunology. 6: 231-7. PMID 7912079 DOI: 10.1016/0952-7915(94)90096-5  0.493
1993 Wang CY, Petryniak B, Thompson CB, Kaelin WG, Leiden JM. Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein. Science (New York, N.Y.). 260: 1330-5. PMID 8493578 DOI: 10.1126/Science.8493578  0.477
1993 Leiden JM. Transcriptional regulation of T cell receptor genes. Annual Review of Immunology. 11: 539-70. PMID 8476572 DOI: 10.1146/annurev.iy.11.040193.002543  0.413
1993 Boise LH, Petryniak B, Mao X, June CH, Wang CY, Lindsten T, Bravo R, Kovary K, Leiden JM, Thompson CB. The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. Molecular and Cellular Biology. 13: 1911-9. PMID 8441422 DOI: 10.1128/Mcb.13.3.1911  0.411
1993 Metzger JM, Parmacek MS, Barr E, Pasyk K, Lin WI, Cochrane KL, Field LJ, Leiden JM. Skeletal troponin C reduces contractile sensitivity to acidosis in cardiac myocytes from transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 9036-40. PMID 8415650 DOI: 10.1073/Pnas.90.19.9036  0.312
1992 Parmacek MS, Vora AJ, Shen T, Barr E, Jung F, Leiden JM. Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene. Molecular and Cellular Biology. 12: 1967-76. PMID 1569934 DOI: 10.1128/Mcb.12.5.1967  0.422
1992 Wang CY, Petryniak B, Ho IC, Thompson CB, Leiden JM. Evolutionarily conserved Ets family members display distinct DNA binding specificities. The Journal of Experimental Medicine. 175: 1391-9. PMID 1569404 DOI: 10.1084/Jem.175.5.1391  0.384
1992 Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B, Leiden JM. cis-Acting Sequences Required for Inducible Interleukin-2 Enhancer Function Bind a Novel Ets-Related Protein, Elf-1 Molecular and Cellular Biology. 12: 1043-1053. PMID 1545787 DOI: 10.1128/Mcb.12.3.1043  0.302
1992 Karpinski BA, Morle GD, Huggenvik J, Uhler MD, Leiden JM. Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element. Proceedings of the National Academy of Sciences of the United States of America. 89: 4820-4. PMID 1534408 DOI: 10.1073/Pnas.89.11.4820  0.393
1992 Leiden JM. Transcriptional regulation during T-cell development: the alpha TCR gene as a molecular model. Immunology Today. 13: 22-30. PMID 1531412 DOI: 10.1016/0167-5699(92)90200-Q  0.481
1992 Leiden JM, Wang CY, Petryniak B, Markovitz DM, Nabel GJ, Thompson CB. A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells. Journal of Virology. 66: 5890-7. PMID 1527846 DOI: 10.1128/Jvi.66.10.5890-5897.1992  0.343
1992 Maksymowych WP, Gabriel CA, Luyrink L, Melin-Aldana H, Elma M, Giannini EH, Lovell DJ, Kerckhove CV, Leiden J, Choi E, Glass DN. Polymorphism in a T-cell receptor variable gene is associated with susceptibility to a juvenile rheumatoid arthritis subset. Immunogenetics. 35: 257-262. PMID 1347283 DOI: 10.1007/Bf00166831  0.329
1992 Oosterwegel M, Timmerman J, Leiden J, Clevers H. Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis Developmental Immunology. 3: 1-11. PMID 1343100 DOI: 10.1155/1992/27903  0.365
1992 Turka LA, Linsley PS, Lin H, Brady W, Leiden JM, Wei RQ, Gibson ML, Zheng XG, Myrdal S, Gordon D. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proceedings of the National Academy of Sciences of the United States of America. 89: 11102-5. PMID 1332070 DOI: 10.1073/Pnas.89.22.11102  0.413
1992 Barr E, Lin H, Parmacek MS, Leiden JM. Direct gene transfer into cardiac myocytes in vivo Methods. 4: 169-176. DOI: 10.1016/1046-2023(92)90049-E  0.352
1992 Barr E, Pamacek MS, Leiden JM. In vivo studies of transcriptional regulation in cardiac myocytes using direct gene transfer into myocardium Journal of Molecular and Cellular Cardiology. 24. DOI: 10.1016/0022-2828(92)92944-8  0.378
1991 Leinwand LA, Leiden JM. Gene transfer into cardiac myocytes in vivo. Trends in Cardiovascular Medicine. 1: 271-6. PMID 21239293 DOI: 10.1016/1050-1738(91)90042-D  0.392
1991 Barr E, Leiden JM. Systemic delivery of recombinant proteins by genetically modified myoblasts. Science (New York, N.Y.). 254: 1507-9. PMID 1962212 DOI: 10.1126/Science.1962212  0.311
1991 Ho IC, Vorhees P, Marin N, Oakley BK, Tsai SF, Orkin SH, Leiden JM. Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. The Embo Journal. 10: 1187-92. PMID 1827068 DOI: 10.1002/J.1460-2075.1991.Tb08059.X  0.446
1990 Parmacek MS, Bengur AR, Vora AJ, Leiden JM. The structure and regulation of expression of the murine fast skeletal troponin C gene. Identification of a developmentally regulated, muscle-specific transcriptional enhancer. The Journal of Biological Chemistry. 265: 15970-6. PMID 2394755  0.324
1990 Ho IC, Leiden JM. Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements. Molecular and Cellular Biology. 10: 4720-7. PMID 2388624 DOI: 10.1128/Mcb.10.9.4720  0.392
1990 Ho IC, Bhat NK, Gottschalk LR, Lindsten T, Thompson CB, Papas TS, Leiden JM. Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer. Science (New York, N.Y.). 250: 814-8. PMID 2237431 DOI: 10.1126/Science.2237431  0.41
1990 Tjoelker LW, Carlson LM, Lee K, Lahti J, McCormack WT, Leiden JM, Chen CL, Cooper MD, Thompson CB. Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain. Proceedings of the National Academy of Sciences of the United States of America. 87: 7856-60. PMID 2236002 DOI: 10.1073/Pnas.87.20.7856  0.363
1990 Ho IC, Leiden JM. The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor. The Journal of Experimental Medicine. 172: 1443-9. PMID 2230652 DOI: 10.1084/Jem.172.5.1443  0.41
1990 Lin H, Parmacek MS, Morle G, Bolling S, Leiden JM. Expression of recombinant genes in myocardium in vivo after direct injection of DNA. Circulation. 82: 2217-21. PMID 2173647 DOI: 10.1161/01.Cir.82.6.2217  0.372
1990 Gottschalk LR, Leiden JM. Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes. Molecular and Cellular Biology. 10: 5486-95. PMID 2144610 DOI: 10.1128/Mcb.10.10.5486  0.401
1989 Parmacek MS, Karpinski BA, Gottesdiener KM, Thompson CB, Leiden JM. Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Research. 17: 1915-31. PMID 2928113 DOI: 10.1093/Nar/17.5.1915  0.374
1989 Leiden JM, Yang LH, Morle GD, June CH, Lindsten T, Thompson CB, Karpinski B. The 4F2 heavy chain gene: a molecular model of inducible gene expression in human T cells. Journal of Autoimmunity. 2: 67-79. PMID 2789062 DOI: 10.1016/0896-8411(89)90118-2  0.491
1989 Ho IC, Yang LH, Morle G, Leiden JM. A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus. Proceedings of the National Academy of Sciences of the United States of America. 86: 6714-8. PMID 2788889 DOI: 10.1073/Pnas.86.17.6714  0.376
1989 Karpinski BA, Yang LH, Cacheris P, Morle GD, Leiden JM. The first intron of the 4F2 heavy-chain gene contains a transcriptional enhancer element that binds multiple nuclear proteins. Molecular and Cellular Biology. 9: 2588-97. PMID 2761540 DOI: 10.1128/Mcb.9.6.2588  0.43
1989 Parmacek MS, Leiden JM. Structure and expression of the murine slow/cardiac troponin C gene. The Journal of Biological Chemistry. 264: 13217-25. PMID 2753913  0.308
1989 June CH, Jackson KM, Ledbetter JA, Leiden JM, Lindsten T, Thompson CB. Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes. Journal of Autoimmunity. 2: 55-65. PMID 2550020 DOI: 10.1016/0896-8411(89)90117-0  0.36
1989 Leiden JM, Karpinski BA, Gottschalk L, Kornbluth J. Susceptibility to natural killer cell-mediated cytolysis is independent of the level of target cell class I HLA expression. Journal of Immunology (Baltimore, Md. : 1950). 142: 2140-7. PMID 2493507 DOI: 10.1159/000416322  0.328
1989 Thompson CB, Lindsten T, Ledbetter JA, Kunkel SL, Young HA, Emerson SG, Leiden JM, June CH. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proceedings of the National Academy of Sciences of the United States of America. 86: 1333-7. PMID 2465550 DOI: 10.1073/Pnas.86.4.1333  0.386
1989 Maksymowych WP, Luyrink L, Kerckhove CV, Lovell D, Taylor J, Leiden J, Choi E, Glass DN. 9.7-04 A T cell receptor Vb gene fragment related RFLP defines a polymorphic marker in Northern European populations Human Immunology. 26: 109. DOI: 10.1016/0198-8859(89)90805-7  0.356
1988 Leiden JM, Gottesdiener KM, Quertermous T, Coury L, Bray RA, Gottschalk L, Gebel H, Seidman JG, Strominger JL, Landay AL. T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes. Immunogenetics. 27: 231-8. PMID 3346041 DOI: 10.1007/Bf00376117  0.418
1988 Lindsten T, June CH, Thompson CB, Leiden JM. Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms. Molecular and Cellular Biology. 8: 3820-6. PMID 3265471 DOI: 10.1128/Mcb.8.9.3820  0.471
1988 Gottesdiener KM, Karpinski BA, Lindsten T, Strominger JL, Jones NH, Thompson CB, Leiden JM. Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation. Molecular and Cellular Biology. 8: 3809-19. PMID 3265470 DOI: 10.1128/Mcb.8.9.3809  0.459
1987 Quackenbush E, Clabby M, Gottesdiener KM, Barbosa J, Jones NH, Strominger JL, Speck S, Leiden JM. Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. Proceedings of the National Academy of Sciences of the United States of America. 84: 6526-30. PMID 3476959 DOI: 10.1073/Pnas.84.18.6526  0.323
1986 Leiden JM, Dialynas DP, Duby AD, Murre C, Seidman J, Strominger JL. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. Molecular and Cellular Biology. 6: 3207-14. PMID 3491297 DOI: 10.1128/Mcb.6.9.3207  0.403
1986 Dialynas DP, Murre C, Quertermous T, Boss JM, Leiden JM, Seidman JG, Strominger JL. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. Proceedings of the National Academy of Sciences of the United States of America. 83: 2619-23. PMID 3458221 DOI: 10.1073/Pnas.83.8.2619  0.316
1986 Leiden JM, Fraser JD, Strominger JL. The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone. Immunogenetics. 24: 17-23. PMID 2426193 DOI: 10.1007/Bf00372293  0.4
1985 Jones N, Leiden J, Dialynas D, Fraser J, Clabby M, Kishimoto T, Strominger JL, Andrews D, Lane W, Woody J. Partial primary structure of the alpha and beta chains of human tumor T-cell receptors. Science (New York, N.Y.). 227: 311-4. PMID 3871253 DOI: 10.1126/Science.3871253  0.343
1980 Leiden JM, Frenkel N, Sabourin D, Davidson RL. Mapping of the herpes simplex virus DNA sequences present in herpes simplex virus type-1 thymidine kinase-transformed cells. Somatic Cell Genetics. 6: 789-98. PMID 6255619 DOI: 10.1007/BF01538977  0.334
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