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Marc J. Lajoie, Ph.D. - Publications

Affiliations: 
2014 Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Computational Genetics
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Filsinger GT, Wannier TM, Pedersen FB, Lutz ID, Zhang J, Stork DA, Debnath A, Gozzi K, Kuchwara H, Volf V, Wang S, Rios X, Gregg CJ, Lajoie MJ, Shipman SL, et al. Characterizing the portability of phage-encoded homologous recombination proteins. Nature Chemical Biology. PMID 33462496 DOI: 10.1038/s41589-020-00710-5  0.778
2020 Kirkpatrick RL, Lewis K, Langan RA, Lajoie MJ, Boyken SE, Eakman M, Baker D, Zalatan JG. Conditional Recruitment to a DNA-Bound CRISPR-Cas Complex Using a Colocalization-Dependent Protein Switch. Acs Synthetic Biology. PMID 32816470 DOI: 10.1021/Acssynbio.0C00012  0.433
2020 Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM. Improved bacterial recombineering by parallelized protein discovery. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467157 DOI: 10.1073/Pnas.2001588117  0.688
2019 Langan RA, Boyken SE, Ng AH, Samson JA, Dods G, Westbrook AM, Nguyen TH, Lajoie MJ, Chen Z, Berger S, Mulligan VK, Dueber JE, Novak WRP, El-Samad H, Baker D. De novo design of bioactive protein switches. Nature. PMID 31341284 DOI: 10.1038/S41586-019-1432-8  0.311
2018 Frumkin I, Lajoie MJ, Gregg CJ, Hornung G, Church GM, Pilpel Y. Codon usage of highly expressed genes affects proteome-wide translation efficiency. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735666 DOI: 10.1073/Pnas.1719375115  0.586
2017 Butterfield GL, Lajoie MJ, Gustafson HH, Sellers DL, Nattermann U, Ellis D, Bale JB, Ke S, Lenz GH, Yehdego A, Ravichandran R, Pun SH, King NP, Baker D. Evolution of a designed protein assembly encapsulating its own RNA genome. Nature. PMID 29236688 DOI: 10.1038/Nature25157  0.511
2017 Mukai T, Lajoie MJ, Englert M, Söll D. Rewriting the Genetic Code. Annual Review of Microbiology. PMID 28697669 DOI: 10.1146/Annurev-Micro-090816-093247  0.487
2017 Goodman DB, Kuznetsov G, Lajoie MJ, Ahern BW, Napolitano MG, Chen KY, Chen C, Church GM. Millstone: software for multiplex microbial genome analysis and engineering. Genome Biology. 18: 101. PMID 28545559 DOI: 10.1186/S13059-017-1223-1  0.785
2017 Kuznetsov G, Goodman DB, Filsinger GT, Landon M, Rohland N, Aach J, Lajoie MJ, Church GM. Optimizing complex phenotypes through model-guided multiplex genome engineering. Genome Biology. 18: 100. PMID 28545477 DOI: 10.1186/S13059-017-1217-Z  0.8
2017 Italia JS, Addy PS, Wrobel CJ, Crawford LA, Lajoie MJ, Zheng Y, Chatterjee A. An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes. Nature Chemical Biology. PMID 28192410 DOI: 10.1038/Nchembio.2312  0.477
2016 Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM. Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 113: E5588-97. PMID 27601680 DOI: 10.1073/Pnas.1605856113  0.776
2016 Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, ... ... Lajoie MJ, et al. Design, synthesis, and testing toward a 57-codon genome. Science (New York, N.Y.). 353: 819-22. PMID 27540174 DOI: 10.1126/Science.Aaf3639  0.807
2016 Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, et al. The Genome Project-Write. Science (New York, N.Y.). PMID 27256881 DOI: 10.1126/Science.Aaf6850  0.803
2016 Zheng Y, Lajoie MJ, Italia JS, Chin MA, Church GM, Chatterjee A. Performance of optimized noncanonical amino acid mutagenesis systems in the absence of release factor 1. Molecular Biosystems. 12: 1746-9. PMID 27027374 DOI: 10.1039/C6Mb00070C  0.561
2015 Klein JC, Lajoie MJ, Schwartz JJ, Strauch EM, Nelson J, Baker D, Shendure J. Multiplex pairwise assembly of array-derived DNA oligonucleotides. Nucleic Acids Research. PMID 26553805 DOI: 10.1093/Nar/Gkv1177  0.519
2015 Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM. Corrigendum: Biocontainment of genetically modified organisms by synthetic protein design. Nature. 527: 264. PMID 26416745 DOI: 10.1038/Nature15536  0.473
2015 Lajoie MJ, Söll D, Church GM. Overcoming challenges in engineering the genetic code. Journal of Molecular Biology. PMID 26348789 DOI: 10.1016/J.Jmb.2015.09.003  0.582
2015 Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM. Biocontainment of genetically modified organisms by synthetic protein design. Nature. 518: 55-60. PMID 25607366 DOI: 10.1038/Nature14121  0.574
2014 Chatterjee A, Lajoie MJ, Xiao H, Church GM, Schultz PG. A bacterial strain with a unique quadruplet codon specifying non-native amino acids. Chembiochem : a European Journal of Chemical Biology. 15: 1782-6. PMID 24867343 DOI: 10.1002/Cbic.201402104  0.572
2014 Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM. Rational optimization of tolC as a powerful dual selectable marker for genome engineering. Nucleic Acids Research. 42: 4779-90. PMID 24452804 DOI: 10.1093/Nar/Gkt1374  0.761
2014 Ling J, Daoud R, Lajoie MJ, Church GM, Söll D, Lang BF. Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria. Nucleic Acids Research. 42: 499-508. PMID 24049072 DOI: 10.1093/Nar/Gkt842  0.541
2013 Lajoie MJ, Kosuri S, Mosberg JA, Gregg CJ, Zhang D, Church GM. Probing the limits of genetic recoding in essential genes. Science (New York, N.Y.). 342: 361-3. PMID 24136967 DOI: 10.1126/Science.1241460  0.803
2013 Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, et al. Genomically recoded organisms expand biological functions. Science (New York, N.Y.). 342: 357-60. PMID 24136966 DOI: 10.1126/Science.1241459  0.762
2012 Mosberg JA, Gregg CJ, Lajoie MJ, Wang HH, Church GM. Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases. Plos One. 7: e44638. PMID 22957093 DOI: 10.1371/Journal.Pone.0044638  0.797
2012 Lajoie MJ, Gregg CJ, Mosberg JA, Washington GC, Church GM. Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering. Nucleic Acids Research. 40: e170. PMID 22904085 DOI: 10.1093/Nar/Gks751  0.819
2012 Carr PA, Wang HH, Sterling B, Isaacs FJ, Lajoie MJ, Xu G, Church GM, Jacobson JM. Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection. Nucleic Acids Research. 40: e132. PMID 22638574 DOI: 10.1093/Nar/Gks455  0.825
2011 Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, et al. Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science (New York, N.Y.). 333: 348-53. PMID 21764749 DOI: 10.1126/Science.1205822  0.77
2010 Mosberg JA, Lajoie MJ, Church GM. Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate. Genetics. 186: 791-9. PMID 20813883 DOI: 10.1534/Genetics.110.120782  0.766
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