| Year |
Citation |
Score |
| 2021 |
Jiang W, Lin YC, Botello-Smith W, Contreras J, Harris AL, Maragliano L, Luo YL. Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning. Biophysical Journal. PMID 34214529 DOI: 10.1016/j.bpj.2021.06.024 |
0.681 |
|
| 2020 |
Gaete PS, Lillo MA, López W, Liu Y, Jiang W, Luo Y, Harris AL, Contreras JE. A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels. The Journal of General Physiology. 152. PMID 33074302 DOI: 10.1085/jgp.202012607 |
0.698 |
|
| 2020 |
Gaete PS, Lillo MA, Lopez WI, Liu Y, Harris AL, Contreras JE. Novel Biophysical Properties of Molecular Permeation in CALHM1 and Connexin Channels Biophysical Journal. 118: 270a. DOI: 10.1016/J.Bpj.2019.11.1555 |
0.412 |
|
| 2018 |
Valdez Capuccino JM, Chatterjee P, García IE, Botello-Smith WM, Zhang H, Harris AL, Luo Y, Contreras JE. The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening. The Journal of General Physiology. PMID 30530766 DOI: 10.1085/Jgp.201812219 |
0.685 |
|
| 2018 |
Harris AL. Electrical coupling and its channels. The Journal of General Physiology. PMID 30389716 DOI: 10.1085/Jgp.201812203 |
0.449 |
|
| 2017 |
Trease AJ, Capuccino JMV, Contreras J, Harris AL, Sorgen PL. Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization. Journal of Molecular and Cellular Cardiology. PMID 28754342 DOI: 10.1016/J.Yjmcc.2017.07.010 |
0.321 |
|
| 2016 |
Lopez W, Ramachandran J, Alsamarah A, Luo Y, Harris AL, Contreras JE. Mechanism of gating by calcium in connexin hemichannels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872296 DOI: 10.1073/Pnas.1609378113 |
0.696 |
|
| 2016 |
Luo Y, Rossi AR, Harris AL. Computational Studies of Molecular Permeation through Connexin26 Channels. Biophysical Journal. 110: 584-99. PMID 26840724 DOI: 10.1016/J.Bpj.2015.11.3528 |
0.429 |
|
| 2016 |
Bennett BC, Purdy MD, Baker KA, Acharya C, McIntire WE, Stevens RC, Zhang Q, Harris AL, Abagyan R, Yeager M. An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nature Communications. 7: 8770. PMID 26753910 DOI: 10.1038/Ncomms9770 |
0.457 |
|
| 2016 |
Valdez Capuccino JM, Lopez W, Harris AL, Contreras JE. Human Connexin 26 (Cx26) N14K Mutant Alters Hemichannel Calcium and Voltage Sensitivity Biophysical Journal. 110: 117a-118a. DOI: 10.1016/J.Bpj.2015.11.685 |
0.463 |
|
| 2016 |
Lopez WI, Ramachandran J, Harris AL, Contreras JE. Access of Metal Ions and Methanethiosulfonate Reagents to the Calcium-Gated Connexin Hemichannel Pore: Implications for the Location of the Gate Biophysical Journal. 110: 353a. DOI: 10.1016/J.Bpj.2015.11.1902 |
0.367 |
|
| 2015 |
Tong X, Lopez W, Ramachandran J, Ayad WA, Liu Y, Lopez-Rodriguez A, Harris AL, Contreras JE. Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules. The Journal of General Physiology. 146: 245-54. PMID 26324677 DOI: 10.1085/Jgp.201511375 |
0.72 |
|
| 2015 |
Lord SR, Patel N, Liu D, Fenwick J, Gleeson F, Buffa F, Harris AL. Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism. Journal of the National Cancer Institute. Monographs. 2015: 81-6. PMID 26063894 DOI: 10.1093/jncimonographs/lgv011 |
0.347 |
|
| 2015 |
Hong X, Sin WC, Harris AL, Naus CC. Gap junctions modulate glioma invasion by direct transfer of microRNA. Oncotarget. PMID 25978028 DOI: 10.18632/Oncotarget.3904 |
0.307 |
|
| 2015 |
Luo L, Rossi AR, Harris AL. Molecular Dynamics of Selective Sugar Permeation through the Connexin26 Channel Biophysical Journal. 108: 442a. DOI: 10.1016/J.Bpj.2014.11.2413 |
0.44 |
|
| 2014 |
Harris AL, Contreras JE. Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing. Frontiers in Physiology. 5: 113. PMID 24744733 DOI: 10.3389/Fphys.2014.00113 |
0.741 |
|
| 2014 |
Lopez W, Liu Y, Harris AL, Contreras JE. Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels. Channels (Austin, Tex.). 8: 1-4. PMID 24126106 DOI: 10.4161/Chan.26789 |
0.668 |
|
| 2014 |
Xuhui T, Lopez W, Ayad WA, Liu Y, Lopez-Rodriguez A, Harris AL, Contreras JE. On the Use of Chemical Modification to Determine Connexin Hemichannel Topology and Function Biophysical Journal. 106: 556a. DOI: 10.1016/J.Bpj.2013.11.3092 |
0.453 |
|
| 2014 |
Kopanic JL, Contreras JE, Harris AL, Sorgen PL. Peptide NMR Studies of Cx26 Interdomain Interactions and their Regulation by Taurine Biophysical Journal. 106: 480a. DOI: 10.1016/J.Bpj.2013.11.2711 |
0.383 |
|
| 2014 |
Naulin PA, Liu Y, Harris A, Contreras JE, Barrera NP. Structural Studies of Heteromeric Connexin26/30 Hemichannels via Atomic Force Microscopy Imaging Biophysical Journal. 106: 266a. DOI: 10.1016/J.Bpj.2013.11.1558 |
0.337 |
|
| 2013 |
Lopez W, Gonzalez J, Liu Y, Harris AL, Contreras JE. Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y). The Journal of General Physiology. 142: 23-35. PMID 23797420 DOI: 10.1085/Jgp.201210893 |
0.698 |
|
| 2013 |
Autsavapromporn N, De Toledo SM, Jay-Gerin JP, Harris AL, Azzam EI. Human cell responses to ionizing radiation are differentially affected by the expressed connexins. Journal of Radiation Research. 54: 251-9. PMID 23139176 DOI: 10.1093/Jrr/Rrs099 |
0.352 |
|
| 2013 |
Lopez W, Liu Y, Harris AL, Contreras JE. Extracellular Divalent Cations Regulation of Cx26 and Cx30 Hemichannels Biophysical Journal. 104: 632a. DOI: 10.1016/J.Bpj.2012.11.3493 |
0.354 |
|
| 2013 |
Tong X, Lopez W, Liu Y, Harris AL, Contreras JE. Disruption of Salt Bridge Interactions Modifies Gating Kinetics of Connexin Hemichannels Biophysical Journal. 104: 631a-632a. DOI: 10.1016/J.Bpj.2012.11.3492 |
0.457 |
|
| 2012 |
Kwon T, Roux B, Jo S, Klauda JB, Harris AL, Bargiello TA. Molecular dynamics simulations of the Cx26 hemichannel: insights into voltage-dependent loop-gating. Biophysical Journal. 102: 1341-51. PMID 22455917 DOI: 10.1016/J.Bpj.2012.02.009 |
0.381 |
|
| 2012 |
Yuan D, Wang Q, Wu D, Yu M, Zhang S, Li L, Tao L, Harris AL. Monocyte-endothelial adhesion is modulated by Cx43-stimulated ATP release from monocytes. Biochemical and Biophysical Research Communications. 420: 536-41. PMID 22446325 DOI: 10.1016/J.Bbrc.2012.03.027 |
0.351 |
|
| 2012 |
Lopez W, Gonzalez J, Liu Y, Harris A, Contreras JE. A Human Disease Mutation (D50N) Reveals Insights on the Mechanisms for Ca2+ Regulation in Human Connexin26 (hCX26) Hemichannels Biophysical Journal. 102: 108a. DOI: 10.1016/J.Bpj.2011.11.606 |
0.43 |
|
| 2012 |
Harris AL, Liu J, Locke D. Pore Width of Disease-Causing Connexin26 Containing Channels Biophysical Journal. 102: 107a. DOI: 10.1016/J.Bpj.2011.11.601 |
0.462 |
|
| 2011 |
Kwon T, Harris AL, Rossi A, Bargiello TA. Molecular dynamics simulations of the Cx26 hemichannel: evaluation of structural models with Brownian dynamics. The Journal of General Physiology. 138: 475-93. PMID 22006989 DOI: 10.1085/Jgp.201110679 |
0.383 |
|
| 2011 |
Locke D, Kieken F, Tao L, Sorgen PL, Harris AL. Mechanism for modulation of gating of connexin26-containing channels by taurine. The Journal of General Physiology. 138: 321-39. PMID 21844220 DOI: 10.1085/Jgp.201110634 |
0.456 |
|
| 2010 |
Wang Q, You T, Yuan D, Han X, Hong X, He B, Wang L, Tong X, Tao L, Harris AL. Cisplatin and oxaliplatin inhibit gap junctional communication by direct action and by reduction of connexin expression, thereby counteracting cytotoxic efficacy. The Journal of Pharmacology and Experimental Therapeutics. 333: 903-11. PMID 20215407 DOI: 10.1124/Jpet.109.165274 |
0.361 |
|
| 2009 |
He B, Tong X, Wang L, Wang Q, Ye H, Liu B, Hong X, Tao L, Harris AL. Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5803-10. PMID 19723651 DOI: 10.1158/1078-0432.Ccr-09-0811 |
0.32 |
|
| 2009 |
Locke D, Harris AL. Connexin channels and phospholipids: association and modulation. Bmc Biology. 7: 52. PMID 19686581 DOI: 10.1186/1741-7007-7-52 |
0.444 |
|
| 2009 |
Harris AL. Gating on the outside. The Journal of General Physiology. 133: 549-53. PMID 19468073 DOI: 10.1085/Jgp.200910256 |
0.42 |
|
| 2009 |
Tao L, Kieken F, Liu J, Sorgen PL, Harris AL, Locke D. Chemical Gating Mechanism Of Connexin26-containing Channels By Aminosulfonate Biophysical Journal. 96: 286a. DOI: 10.1016/J.Bpj.2008.12.1415 |
0.423 |
|
| 2009 |
Locke D, Harris AL. Connexin Pore Block By ABG-Sugars Biophysical Journal. 96: 285a-286a. DOI: 10.1016/J.Bpj.2008.12.1414 |
0.412 |
|
| 2009 |
Harris AL, Locke D. Permeability of connexin channels Connexins: a Guide. 165-206. DOI: 10.1007/978-1-59745-489-6_7 |
0.325 |
|
| 2007 |
Yeager M, Harris AL. Gap junction channel structure in the early 21st century: facts and fantasies. Current Opinion in Cell Biology. 19: 521-8. PMID 17945477 DOI: 10.1016/J.Ceb.2007.09.001 |
0.416 |
|
| 2007 |
Babich O, Matveev V, Harris AL, Shirokov R. Ca2+-dependent inactivation of CaV1.2 channels prevents Gd3+ block: does Ca2+ block the pore of inactivated channels? The Journal of General Physiology. 129: 477-83. PMID 17535960 DOI: 10.1085/Jgp.200709734 |
0.703 |
|
| 2007 |
Harris AL. Connexin channel permeability to cytoplasmic molecules. Progress in Biophysics and Molecular Biology. 94: 120-43. PMID 17470375 DOI: 10.1016/J.Pbiomolbio.2007.03.011 |
0.452 |
|
| 2007 |
Locke D, Jamieson S, Stein T, Liu J, Hodgins MB, Harris AL, Gusterson B. Nature of Cx30-containing channels in the adult mouse mammary gland. Cell and Tissue Research. 328: 97-107. PMID 17120054 DOI: 10.1007/S00441-006-0301-6 |
0.43 |
|
| 2007 |
Tao L, Harris AL. 2-aminoethoxydiphenyl borate directly inhibits channels composed of connexin26 and/or connexin32. Molecular Pharmacology. 71: 570-9. PMID 17095584 DOI: 10.1124/Mol.106.027508 |
0.459 |
|
| 2006 |
Locke D, Koreen IV, Harris AL. Isoelectric points and post-translational modifications of connexin26 and connexin32. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1221-3. PMID 16645047 DOI: 10.1096/Fj.05-5309Fje |
0.416 |
|
| 2006 |
Ayad WA, Locke D, Koreen IV, Harris AL. Heteromeric, but not homomeric, connexin channels are selectively permeable to inositol phosphates. The Journal of Biological Chemistry. 281: 16727-39. PMID 16601118 DOI: 10.1074/Jbc.M600136200 |
0.453 |
|
| 2005 |
Locke D, Liu J, Harris AL. Lipid rafts prepared by different methods contain different connexin channels, but gap junctions are not lipid rafts. Biochemistry. 44: 13027-42. PMID 16185071 DOI: 10.1021/Bi050495A |
0.409 |
|
| 2004 |
Locke D, Stein T, Davies C, Morris J, Harris AL, Evans WH, Monaghan P, Gusterson B. Altered permeability and modulatory character of connexin channels during mammary gland development. Experimental Cell Research. 298: 643-60. PMID 15265710 DOI: 10.1016/J.Yexcr.2004.05.003 |
0.463 |
|
| 2004 |
Koreen IV, Elsayed WA, Liu YJ, Harris AL. Tetracycline-regulated expression enables purification and functional analysis of recombinant connexin channels from mammalian cells. The Biochemical Journal. 383: 111-9. PMID 15242349 DOI: 10.1042/Bj20040806 |
0.423 |
|
| 2004 |
Tao L, Harris AL. Biochemical requirements for inhibition of Connexin26-containing channels by natural and synthetic taurine analogs. The Journal of Biological Chemistry. 279: 38544-54. PMID 15234974 DOI: 10.1074/Jbc.M405654200 |
0.362 |
|
| 2004 |
Locke D, Koreen IV, Liu JY, Harris AL. Reversible pore block of connexin channels by cyclodextrins. The Journal of Biological Chemistry. 279: 22883-92. PMID 15044473 DOI: 10.1074/Jbc.M401980200 |
0.33 |
|
| 2003 |
Locke D, Wang LX, Bevans CG, Lee YC, Harris AL. Open pore block of connexin26 and connexin32 hemichannels by neutral, acidic and basic glycoconjugates. Cell Communication & Adhesion. 10: 239-44. PMID 14681023 DOI: 10.1080/Cac.10.4-6.239.244 |
0.392 |
|
| 2002 |
Harris AL. Voltage-sensing and substate rectification: moving parts of connexin channels. The Journal of General Physiology. 119: 165-9. PMID 11815666 DOI: 10.1085/Jgp.119.2.165 |
0.452 |
|
| 2001 |
Harris AL. Emerging issues of connexin channels: Biophysics fills the gap Quarterly Reviews of Biophysics. 34: 325-472. PMID 11838236 DOI: 10.1017/S0033583501003705 |
0.483 |
|
| 1999 |
Suchyna TM, Nitsche JM, Chilton M, Harris AL, Veenstra RD, Nicholson BJ. Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels Biophysical Journal. 77: 2968-2987. PMID 10585920 DOI: 10.1016/S0006-3495(99)77129-8 |
0.49 |
|
| 1999 |
Bevans CG, Harris AL. Direct high affinity modulation of connexin channel activity by cyclic nucleotides Journal of Biological Chemistry. 274: 3720-3725. PMID 9920924 DOI: 10.1074/Jbc.274.6.3720 |
0.446 |
|
| 1999 |
Bevans CG, Harris AL. Regulation of connexin channels by pH: Direct action of the protonated form of taurine and other aminosulfonates Journal of Biological Chemistry. 274: 3711-3719. PMID 9920923 DOI: 10.1074/Jbc.274.6.3711 |
0.424 |
|
| 1998 |
Bevans CG, Kordel M, Rhee SK, Harris AL. Isoform composition of connexin channels determines selectivity among second messengers and uncharged molecules Journal of Biological Chemistry. 273: 2808-2816. PMID 9446589 DOI: 10.1074/Jbc.273.5.2808 |
0.456 |
|
| 1996 |
Rhee SK, Bevans CG, Harris AL. Channel-forming activity of immunoaffinity-purified connexin32 in single phospholipid membranes Biochemistry. 35: 9212-9223. PMID 8703927 DOI: 10.1021/Bi960295M |
0.472 |
|
| 1995 |
Veenstra RD, Wang HZ, Beblo DA, Chilton MG, Harris AL, Beyer EC, Brink PR. Selectivity of connexin-specific gap junctions does not correlate with channel conductance Circulation Research. 77: 1156-1165. PMID 7586229 DOI: 10.1161/01.Res.77.6.1156 |
0.481 |
|
| 1995 |
Brutyan RA, DeMaria C, Harris AL. Horizontal 'solvent-free' lipid bimolecular membranes with two-sided access can be formed and facilitate ion channel reconstitution Bba - Biomembranes. 1236: 339-344. PMID 7540872 DOI: 10.1016/0005-2736(95)00089-L |
0.341 |
|
| 1992 |
Harris AL, Walter A, Paul D, Goodenough DA, Zimmerberg J. Ion channels in single bilayers induced by rat connexin32. Brain Research. Molecular Brain Research. 15: 269-80. PMID 1279354 DOI: 10.1016/0169-328X(92)90118-U |
0.72 |
|
| 1989 |
Harris AL, Walter A, Zimmerberg J. Transport-specific isolation of large channels reconstituted into lipid vesicles. The Journal of Membrane Biology. 109: 243-50. PMID 2477547 DOI: 10.1007/Bf01870281 |
0.385 |
|
| 1984 |
Spray DC, Nerbonne J, Campos de Carvalho A, Harris AL, Bennett MV. Substituted benzyl acetates: a new class of compounds that reduce gap junctional conductance by cytoplasmic acidification. The Journal of Cell Biology. 99: 174-9. PMID 6736125 DOI: 10.1083/Jcb.99.1.174 |
0.584 |
|
| 1984 |
Spray DC, White RL, de Carvalho AC, Harris AL, Bennett MV. Gating of gap junction channels. Biophysical Journal. 45: 219-30. PMID 6324905 DOI: 10.1016/S0006-3495(84)84150-8 |
0.652 |
|
| 1983 |
Harris AL, Spray DC, Bennett MV. Control of intercellular communication by voltage dependence of gap junctional conductance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 79-100. PMID 6822860 |
0.566 |
|
| 1983 |
Harris AL, Spray DC, Bennett MVL. Control of intercellular communication by voltage dependence of gap junctional conductance The Journal of Neuroscience. 3: 79-100. DOI: 10.1523/Jneurosci.03-01-00079.1983 |
0.354 |
|
| 1982 |
Bennett MV, Spray DC, Harris AL, Ginzberg RD, Campos de Carvalho A, White RL. Control of intercellular communication by way of gap junctions. Harvey Lectures. 78: 23-57. PMID 6926989 |
0.503 |
|
| 1982 |
Spray DC, Stern JH, Harris AL, Bennett MV. Gap junctional conductance: comparison of sensitivities to H and Ca ions. Proceedings of the National Academy of Sciences of the United States of America. 79: 441-5. PMID 6281771 DOI: 10.1073/Pnas.79.2.441 |
0.591 |
|
| 1981 |
Spray DC, Harris AL, Bennett MV. Gap junctional conductance is a simple and sensitive function of intracellular pH. Science (New York, N.Y.). 211: 712-5. PMID 6779379 DOI: 10.1126/Science.6779379 |
0.637 |
|
| 1981 |
Spray DC, Harris AL, Bennett MV. Comparison of pH and calcium dependence of gap junctional conductance. Kroc Foundation Series. 15: 445-61. PMID 6281397 |
0.526 |
|
| 1981 |
Harris AL, Spray DC, Bennett MV. Kinetic properties of a voltage-dependent junctional conductance. The Journal of General Physiology. 77: 95-117. PMID 6259275 DOI: 10.1085/Jgp.77.1.95 |
0.632 |
|
| 1981 |
Spray DC, Harris AL, Bennett MV. Equilibrium properties of a voltage-dependent junctional conductance. The Journal of General Physiology. 77: 77-93. PMID 6259274 DOI: 10.1085/Jgp.77.1.77 |
0.619 |
|
| 1981 |
Bennett MVL, Spray DC, Harris AL. Electrical coupling in development Integrative and Comparative Biology. 21: 413-427. DOI: 10.1093/Icb/21.2.413 |
0.376 |
|
| 1981 |
Bennett MVL, Spray DC, Harris AL. Gap junctions and development Trends in Neurosciences. 4: 159-163. DOI: 10.1016/0166-2236(81)90053-9 |
0.329 |
|
| 1980 |
Hanna RB, Model PG, Spray DC, Bennett MV, Harris AL. Gap junctions in early amphibian embryos. The American Journal of Anatomy. 158: 111-4. PMID 7416050 DOI: 10.1002/Aja.1001580202 |
0.579 |
|
| 1979 |
Spray DC, Harris AL, Bennett MV. Voltage dependence of junctional conductance in early amphibian embryos. Science (New York, N.Y.). 204: 432-4. PMID 312530 DOI: 10.1126/Science.312530 |
0.608 |
|
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