Year |
Citation |
Score |
2021 |
Cairns J, Kalari KR, Ingle JN, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Goodnature B, Goetz MP, Weinshilboum RM, Gao H, Wang L. Interaction between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early Stage Breast Cancer. Clinical Pharmacology and Therapeutics. PMID 34048027 DOI: 10.1002/cpt.2311 |
0.304 |
|
2020 |
Nguyen TTL, Liu D, Ho MF, Athreya AP, Weinshilboum R. Selective Serotonin Reuptake Inhibitor Pharmaco-Omics: Mechanisms and Prediction. Frontiers in Pharmacology. 11: 614048. PMID 33510640 DOI: 10.3389/fphar.2020.614048 |
0.312 |
|
2020 |
Ho MF, Zhang C, Zhang L, Wei L, Zhou Y, Moon I, Geske JR, Choi DS, Biernacka J, Frye M, Wen Z, Karpyak VM, Li H, Weinshilboum R. TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response. Molecular Psychiatry. PMID 32753686 DOI: 10.1038/S41380-020-0855-9 |
0.344 |
|
2020 |
Zhang L, Sarangi V, Moon I, Yu J, Liu D, Devarajan S, Reid JM, Kalari KR, Wang L, Weinshilboum R. CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants. Clinical and Translational Science. PMID 32004414 DOI: 10.1111/Cts.12758 |
0.383 |
|
2020 |
Myasoedova E, Athreya A, Crowson CS, Weinshilboum R, Wang L, Matteson E. Fri0046 Pharmacogenomics-Driven Individualized Prediction Of Treatment Response To Methotrexate In Patients With Rheumatoid Arthritis: A Machine Learning Approach Annals of the Rheumatic Diseases. 79: 598-598. DOI: 10.1136/Annrheumdis-2020-Eular.4993 |
0.33 |
|
2019 |
Neavin DR, Lee JH, Liu D, Ye Z, Li H, Wang L, Ordog T, Weinshilboum RM. Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor Binding Sites Influence AHR Ligand-Dependent Gene Expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31292129 DOI: 10.1124/Dmd.119.087312 |
0.356 |
|
2019 |
Bodkin JA, Coleman MJ, Godfrey LJ, Carvalho CMB, Morgan CJ, Suckow RF, Anderson T, Ongur D, Kaufman MJ, Lewandowski KE, Siegel AJ, Waldstreicher E, Grochowski CM, Javitt DC, Rujescu D, ... ... Weinshilboum R, et al. Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene. Biological Psychiatry. PMID 31279534 DOI: 10.1016/J.Biopsych.2019.04.031 |
0.665 |
|
2019 |
Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, ... ... Weinshilboum RM, et al. Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction between SLC38A7 and ALPPL2. Clinical Pharmacology and Therapeutics. PMID 30648747 DOI: 10.1002/Cpt.1359 |
0.345 |
|
2019 |
Thompson K, Alaparthi T, Sinnwell J, Carlson E, Tang X, Bockol M, Vedell P, Ingle J, Suman V, Weinshilboum R, Wang L, Boughey J, Kalari K, Goetz M. Abstract P1-03-04: Molecular subtyping of androgen receptor-positive patients using gene expression profiles Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P1-03-04 |
0.311 |
|
2019 |
Fabbri C, Breen G, Tansey K, Perlis R, Investigators G, Biernacka J, Weinshilboum R, Uher R, Lewis C. Meta-Analysis Of Cyp2C19 Association With Efficacy And Side Effects Of Citalopram And Escitalopram Using Data From Genome-Wide Association Studies European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.049 |
0.375 |
|
2018 |
Ward J, Graham N, Strawbridge RJ, Ferguson A, Jenkins G, Chen W, Hodgson K, Frye M, Weinshilboum R, Uher R, Lewis CM, Biernacka J, Smith DJ. Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts. Plos One. 13: e0203896. PMID 30240446 DOI: 10.1371/Journal.Pone.0203896 |
0.314 |
|
2018 |
Liu D, Qin S, Ray B, Kalari KR, Wang L, Weinshilboum RM. Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent Induction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29980579 DOI: 10.1124/dmd.118.082164 |
0.35 |
|
2018 |
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, ... ... Weinshilboum R, et al. Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients. The Pharmacogenomics Journal. PMID 29795407 DOI: 10.1038/S41397-018-0025-5 |
0.364 |
|
2018 |
Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, ... ... Weinshilboum RM, et al. Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pharmacogenetics and Genomics. 28: 147-152. PMID 29768301 DOI: 10.1097/FPC.0000000000000337 |
0.325 |
|
2018 |
Yu J, Qin B, Moyer AM, Nowsheen S, Liu T, Qin S, Zhuang Y, Liu D, Lu SW, Kalari KR, Visscher DW, Copland JA, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, ... ... Weinshilboum R, et al. DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine. The Journal of Clinical Investigation. PMID 29708513 DOI: 10.1172/Jci97924 |
0.309 |
|
2018 |
Bidadi B, Liu D, Kalari KR, Rubner M, Hein A, Beckmann MW, Rack B, Janni W, Fasching PA, Weinshilboum RM, Wang L. Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs inas Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients. Frontiers in Pharmacology. 9: 158. PMID 29593529 DOI: 10.3389/Fphar.2018.00158 |
0.365 |
|
2018 |
Cairns J, Ingle J, Shepherd L, Kubo M, Goetz M, Weinshilboum R, Kalari K, Wang L. Abstract P5-07-01: LncRNA MIR2052HG regulates ERα level and endocrine resistance through LMTK3 by recruiting early growth response protein 1 Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-07-01 |
0.399 |
|
2017 |
Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Sang-Hyuk L, Newhouse S, Patel H, ... ... Weinshilboum RM, et al. New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. The Pharmacogenomics Journal. PMID 29160301 DOI: 10.1038/Tpj.2017.44 |
0.471 |
|
2017 |
Fasching PA, Häberle L, Rack B, Li L, Hein A, Ekici AB, Reis A, Lux MP, Cunningham JM, Ruebner M, Jenkins G, Fridley B, Schneeweiss A, Tesch H, Lichtenegger W, ... ... Weinshilboum RM, et al. Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity. Oncotarget. 8: 78133-78143. PMID 29100455 DOI: 10.18632/Oncotarget.17726 |
0.328 |
|
2017 |
Qin S, Liu D, Kohli M, Wang L, Vedell PT, Hillman DW, Niu N, Yu J, Weinshilboum RM, Wang L. TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer. Clinical Pharmacology and Therapeutics. PMID 29027195 DOI: 10.1002/Cpt.907 |
0.301 |
|
2017 |
Cairns J, Ingle JN, Wickerham LD, Weinshilboum R, Liu M, Wang L. SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1. Plos Genetics. 13: e1007031. PMID 28968398 DOI: 10.1371/journal.pgen.1007031 |
0.315 |
|
2017 |
Nassan M, Jia YF, Jenkins G, Colby C, Feeder S, Choi DS, Veldic M, McElroy SL, Bond DJ, Weinshilboum R, Biernacka JM, Frye MA. Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach. Journal of Psychiatric Research. 95: 208-212. PMID 28886448 DOI: 10.1016/j.jpsychires.2017.07.005 |
0.332 |
|
2017 |
Liu D, Ho MF, Schaid DJ, Scherer SE, Kalari K, Liu M, Biernacka J, Yee V, Evans J, Carlson E, Goetz MP, Kubo M, Wickerham DL, Wang L, Ingle JN, ... Weinshilboum RM, et al. Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes. Npj Breast Cancer. 3: 30. PMID 28856246 DOI: 10.1038/s41523-017-0036-4 |
0.33 |
|
2017 |
Qin S, Ingle JN, Liu M, Yu J, Wickerham DL, Kubo M, Weinshilboum RM, Wang L. Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion. Breast Cancer Research : Bcr. 19: 95. PMID 28821270 DOI: 10.1186/s13058-017-0890-x |
0.322 |
|
2017 |
Ho MF, Ingle JN, Bongartz T, Kalari KR, Goss PE, Shepherd LE, Mushiroda T, Kubo M, Wang L, Weinshilboum RM. TCL1A SNPs and estrogen-mediated toll-like receptor-MYD88-dependent NF-κB activation: SNP and SERM-dependent modification of inflammation and immune response. Molecular Pharmacology. PMID 28615284 DOI: 10.1124/Mol.117.108340 |
0.341 |
|
2017 |
Fasching PA, Häberle L, Rack B, Li L, Hein A, Ekici AB, Reis A, Lux MP, Cunningham JM, Ruebner M, Jenkins G, Fridley B, Schneeweiss A, Tesch H, Lichtenegger W, ... ... Weinshilboum RM, et al. Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity. Oncotarget. PMID 28537877 DOI: 10.18632/oncotarget.17726 |
0.328 |
|
2017 |
Athreya AP, Kalari KR, Cairns J, Gaglio AJ, Wills QF, Niu N, Weinshilboum R, Iyer RK, Wang L. Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer. Oncotarget. 27199-27215. PMID 28423712 DOI: 10.18632/Oncotarget.16109 |
0.339 |
|
2017 |
Cairns J, Ingle J, Dudenkov T, Kalari K, Buzdar A, Kubo M, Robson M, Ellis M, Goss P, Shepherd L, Goetz M, Weinshilboum R, Wang L. Abstract PD1-04: CSMD1 SNPs selectively affect anastrozole response in postmenopausal breast cancer patients Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd1-04 |
0.304 |
|
2016 |
Tamm R, Mägi R, Tremmel R, Winter S, Mihailov E, Smid A, Möricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinarič Raščan I, Metspalu A, Milani L, et al. Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: a meta-analysis of three genome-wide association studies. Clinical Pharmacology and Therapeutics. PMID 27770449 DOI: 10.1002/Cpt.540 |
0.442 |
|
2016 |
Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, ... ... Weinshilboum RM, et al. TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Molecular Psychiatry. PMID 26903268 DOI: 10.1038/Mp.2016.6 |
0.305 |
|
2016 |
Ho MF, Bongartz T, Liu M, Kalari KR, Goss PE, Shepherd LE, Goetz MP, Kubo M, Ingle JN, Wang L, Weinshilboum RM. Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation. Molecular Endocrinology (Baltimore, Md.). me20151267. PMID 26866883 DOI: 10.1210/me.2015-1267 |
0.335 |
|
2016 |
Peddi P, Hurvitz S, Fasching P, Wang L, Cunningham J, Weinshilboum R, Liu D, Quinaux E, Fourmanoir H, Robert N, Valero V, Crown J, Falkson C, Brufsky A, Pienkowski T, et al. Abstract P6-03-09: Genetic polymorphism and correlation with treatment induced cardiotoxicity and prognosis inHER2amplified early breast cancer patients Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-03-09 |
0.419 |
|
2016 |
Ruddy K, Rack B, Schwitulla J, Lambrechts D, Haeberle L, Schramm A, Trapp E, Scholz C, Beutler A, Ginsburg E, Couch F, Partridge A, Wang L, Weinshilboum R, Janni W, et al. Abstract P4-10-07: Genetic predictors of chemotherapy-related amenorrhea Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-10-07 |
0.39 |
|
2016 |
Moyer A, Boughey J, Kalari K, Suman V, McLaughlin S, Moreno-Aspitia A, Northfelt D, Gray R, Sinnwell J, Carlson E, Dockter T, Jones K, Felten S, Conners A, Wieben E, ... ... Weinshilboum R, et al. Abstract P4-04-05: Differential mRNA expression patterns in breast tumors with high vs. low quantity of stromal tumor–Infiltrating lymphocytes Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-04-05 |
0.349 |
|
2016 |
Yu J, Qin B, Boughey J, Moyer A, Visscher D, Sinnwell J, Yin P, Thompson K, Docter T, Kalari K, Suman V, Wieben E, Felten S, Conners A, Jones K, ... ... Weinshilboum R, et al. Abstract P3-07-51: Regulation of DNA methyltransferases via TRAF6 determines breast cancer response to decitabine Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-51 |
0.342 |
|
2015 |
Ellingson MS, Hart SN, Kalari KR, Suman V, Schahl KA, Dockter TJ, Felten SJ, Sinnwell JP, Thompson KJ, Tang X, Vedell PT, Barman P, Sicotte H, Eckel-Passow JE, Northfelt DW, ... ... Weinshilboum R, et al. Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy. Breast Cancer Research and Treatment. 153: 435-43. PMID 26296701 DOI: 10.1007/S10549-015-3545-6 |
0.309 |
|
2015 |
Hein A, Lambrechts D, von Minckwitz G, Häberle L, Eidtmann H, Tesch H, Untch M, Hilfrich J, Schem C, Rezai M, Gerber B, Dan Costa S, Blohmer JU, Schwedler K, Kittel K, ... ... Weinshilboum RM, et al. Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study. International Journal of Cancer. Journal International Du Cancer. 137: 2981-8. PMID 26100253 DOI: 10.1002/ijc.29656 |
0.316 |
|
2015 |
Fagerholm R, Schmidt MK, Khan S, Rafiq S, Tapper W, Aittomäki K, Greco D, Heikkinen T, Muranen TA, Fasching PA, Janni W, Weinshilboum R, Loehberg CR, Hopper JL, Southey MC, et al. The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients. Oncotarget. 6: 7390-407. PMID 25823661 DOI: 10.18632/Oncotarget.3506 |
0.41 |
|
2015 |
Bidadi B, Kalari KR, Rubner M, Hein A, Beckmann MW, Fasching PA, Rack B, Janni W, Weinshilboum R, Wang L. Abstract 5488: Utilizing a pathway based analysis of genome wide association data to identify biomarkers of toxicity in breast cancer patients Cancer Research. 75: 5488-5488. DOI: 10.1158/1538-7445.Am2015-5488 |
0.335 |
|
2015 |
Karpyak V, Biernacka J, Geske J, Jenkins G, Cunningham J, Skime M, Weinshilboum R, Frye M, Choi D. Abstinence Length in Acamprosate-treated Alcoholics and Variability in Glycine and Glutamate Signaling Gene Sets European Psychiatry. 30: 474. DOI: 10.1016/S0924-9338(15)31896-4 |
0.346 |
|
2014 |
Laurie CC, Laurie CA, Smoley SA, Carlson EE, Flinn I, Fridley BL, Greisman HA, Gribben JG, Jelinek DF, Nelson SC, Paietta E, Schaid D, Sun Z, Tallman MS, Weinshilboum R, et al. Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants. Cancer Genetics. 207: 19-30. PMID 24613276 DOI: 10.1016/J.Cancergen.2014.01.004 |
0.314 |
|
2014 |
Thompson KJ, Tang X, Sun Z, Sinnwell JP, Sicotte H, Mahoney DW, Hart S, Vedell PT, Barman P, Passow JEE, Wieben ED, Ingle JN, Boughey JC, Wang L, Weinshilboum R, et al. Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data Cancer Research. 74: 5592-5592. DOI: 10.1158/1538-7445.Am2014-5592 |
0.329 |
|
2014 |
Kalari KR, Tang X, Thompson KJ, Mahoney DW, Barman P, Sinnwell JP, Sicotte H, Vedell P, Hart SN, Dockter TJ, Jones KN, Conners AL, Moyer AM, Visscher DW, Yu J, ... ... Weinshilboum R, et al. Abstract 4185: Analysis of sequencing data to identify potential drug targets for an individual newly diagnosed with basal breast cancer who failed to respond to current standard neoadjuvant chemotherapy Cancer Research. 74: 4185-4185. DOI: 10.1158/1538-7445.Am2014-4185 |
0.382 |
|
2014 |
Ho M-, Liu M, Wang L, Weinshilboum R, Bongartz T. THU0481 Aromatase Inhibitor Treatment and Musculoskeletal Adverse Events: SNP Modulated, Estrogen-Dependent Variation in Ccr6/Ccl20 Expression Annals of the Rheumatic Diseases. 73: 349-349. DOI: 10.1136/Annrheumdis-2014-Eular.5382 |
0.411 |
|
2014 |
Ho M-, Wang L, Weinshilboum R, Bongartz T. OP0193 The Rheumatoid Arthritis -Risk Locus CCR6 and Its Snp-Dependent Response to Estrogen: A Possible Genomic Link between Sex Hormones and the IL-17 Inflammatory Pathway Annals of the Rheumatic Diseases. 73: 135-135. DOI: 10.1136/Annrheumdis-2014-Eular.5289 |
0.387 |
|
2013 |
Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, ... ... Weinshilboum RM, et al. TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression. Molecular Endocrinology (Baltimore, Md.). 27: 657-70. PMID 23518928 DOI: 10.1210/Me.2012-1397 |
0.365 |
|
2013 |
Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, et al. Nomenclature for alleles of the thiopurine methyltransferase gene. Pharmacogenetics and Genomics. 23: 242-8. PMID 23407052 DOI: 10.1097/Fpc.0B013E32835F1Cc0 |
0.443 |
|
2013 |
Ellsworth KA, Moon I, Eckloff BW, Fridley BL, Jenkins GD, Batzler A, Biernacka JM, Abo R, Brisbin A, Ji Y, Hebbring S, Wieben ED, Mrazek DA, Weinshilboum RM, Wang L. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. Pharmacogenetics and Genomics. 23: 156-66. PMID 23324805 DOI: 10.1097/Fpc.0B013E32835Dc133 |
0.668 |
|
2013 |
Ji Y, Biernacka JM, Hebbring S, Chai Y, Jenkins GD, Batzler A, Snyder KA, Drews MS, Desta Z, Flockhart D, Mushiroda T, Kubo M, Nakamura Y, Kamatani N, Schaid D, ... Weinshilboum RM, et al. Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics. The Pharmacogenomics Journal. 13: 456-63. PMID 22907730 DOI: 10.1038/Tpj.2012.32 |
0.665 |
|
2013 |
Motsinger-Reif AA, Jorgenson E, Relling MV, Kroetz DL, Weinshilboum R, Cox NJ, Roden DM. Genome-wide association studies in pharmacogenomics: successes and lessons. Pharmacogenetics and Genomics. 23: 383-94. PMID 20639796 DOI: 10.1097/Fpc.0B013E32833D7B45 |
0.392 |
|
2012 |
Ji Y, Nordgren KK, Chai Y, Hebbring SJ, Jenkins GD, Abo RP, Peng Y, Pelleymounter LL, Moon I, Eckloff BW, Chai X, Zhang J, Fridley BL, Yee VC, Wieben ED, ... Weinshilboum RM, et al. Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1984-92. PMID 22807109 DOI: 10.1124/Dmd.112.046953 |
0.77 |
|
2012 |
Stevens KN, Lindstrom S, Scott CG, Thompson D, Sellers TA, Wang X, Wang A, Atkinson E, Rider DN, Eckel-Passow JE, Varghese JS, Audley T, Brown J, Leyland J, Luben RN, ... ... Weinshilboum R, et al. Identification of a novel percent mammographic density locus at 12q24. Human Molecular Genetics. 21: 3299-305. PMID 22532574 DOI: 10.1093/Hmg/Dds158 |
0.386 |
|
2012 |
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N, Nakamura Y, ... ... Weinshilboum RM, et al. Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenetics and Genomics. 22: 247-53. PMID 22322242 DOI: 10.1097/Fpc.0B013E32835001C9 |
0.648 |
|
2012 |
Hebbring SJ, Chai Y, Ji Y, Abo RP, Jenkins GD, Fridley B, Zhang J, Eckloff BW, Wieben ED, Weinshilboum RM. Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. Journal of Neurochemistry. 120: 881-90. PMID 22220685 DOI: 10.1111/J.1471-4159.2012.07646.X |
0.68 |
|
2012 |
Laurie CC, Laurie CA, Fridley B, Carlson E, Smoley SA, Flinn IW, Tallman MS, Paietta E, Weinshilboum R, Kay NE, Shanafelt TD. Clonal Chromosomal Anomalies Similar to CLL and Other Hematologic Malignancies Can Be Found in “Normal” Individuals Blood. 120: 873-873. DOI: 10.1182/Blood.V120.21.873.873 |
0.302 |
|
2012 |
Weinshilboum R. Abstract PL04-03: SERM breast cancer pharmacogenomics: Beyond biomarkers Cancer Prevention Research. 5. DOI: 10.1158/1940-6207.Prev-12-Pl04-03 |
0.33 |
|
2011 |
Nordgren KK, Peng Y, Pelleymounter LL, Moon I, Abo R, Feng Q, Eckloff B, Yee VC, Wieben E, Weinshilboum RM. Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2135-47. PMID 21813468 DOI: 10.1124/Dmd.111.040857 |
0.792 |
|
2011 |
Wu TY, Fridley BL, Jenkins GD, Batzler A, Wang L, Weinshilboum RM. Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen. International Immunopharmacology. 11: 1057-64. PMID 21396482 DOI: 10.1016/J.Intimp.2011.02.027 |
0.58 |
|
2011 |
Moyer AM, Fridley BL, Jenkins GD, Batzler AJ, Pelleymounter LL, Kalari KR, Ji Y, Chai Y, Nordgren KK, Weinshilboum RM. Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 33-41. PMID 21177773 DOI: 10.1093/Toxsci/Kfq375 |
0.784 |
|
2011 |
Ji Y, Hebbring S, Zhu H, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Zeng Z, Schaid D, Mrazek DA, Kaddurah-Daouk R, Weinshilboum RM. Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. Clinical Pharmacology and Therapeutics. 89: 97-104. PMID 21107318 DOI: 10.1038/Clpt.2010.250 |
0.641 |
|
2011 |
Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM. Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation. Molecular Genetics and Metabolism. 102: 126-33. PMID 21093336 DOI: 10.1016/J.Ymgme.2010.10.010 |
0.665 |
|
2010 |
Li F, Fridley BL, Matimba A, Kalari KR, Pelleymounter L, Moon I, Ji Y, Jenkins GD, Batzler A, Wang L, Weinshilboum RM. Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2329-38. PMID 20855458 DOI: 10.1124/Dmd.110.035220 |
0.364 |
|
2010 |
Wu TY, Peng Y, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Yee VC, Weinshilboum RM. Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics. British Journal of Pharmacology. 161: 1584-98. PMID 20718729 DOI: 10.1111/J.1476-5381.2010.00987.X |
0.618 |
|
2010 |
Pereira NL, Aksoy P, Moon I, Peng Y, Redfield MM, Burnett JC, Wieben ED, Yee VC, Weinshilboum RM. Natriuretic peptide pharmacogenetics: membrane metallo-endopeptidase (MME): common gene sequence variation, functional characterization and degradation. Journal of Molecular and Cellular Cardiology. 49: 864-74. PMID 20692264 DOI: 10.1016/J.Yjmcc.2010.07.020 |
0.301 |
|
2010 |
Kalari KR, Hebbring SJ, Chai HS, Li L, Kocher JP, Wang L, Weinshilboum RM. Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach. Bmc Genomics. 11: 357. PMID 20525348 DOI: 10.1186/1471-2164-11-357 |
0.66 |
|
2010 |
Hartman WR, Pelleymounter LL, Moon I, Kalari K, Liu M, Wu TY, Escande C, Nin V, Chini EN, Weinshilboum RM. CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system. Leukemia & Lymphoma. 51: 1315-25. PMID 20470215 DOI: 10.3109/10428194.2010.483299 |
0.545 |
|
2010 |
Wang L, Ellsworth KA, Moon I, Pelleymounter LL, Eckloff BW, Martin YN, Fridley BL, Jenkins GD, Batzler A, Suman VJ, Ravi S, Dixon JM, Miller WR, Wieben ED, Buzdar A, ... Weinshilboum RM, et al. Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors. Cancer Research. 70: 319-28. PMID 20048079 DOI: 10.1158/0008-5472.Can-09-3224 |
0.35 |
|
2010 |
Ingle J, Liu M, Wickerham D, Schaid D, Mushiroda T, Kubo M, Costantino J, Goetz M, Ames M, Wang L, Vogel V, Paik S, Batzler A, Flockhart D, Wolmark N, ... ... Weinshilboum R, et al. Abstract PD05-02: Genome-Wide Associations of Breast Events and Functional Genomic Studies in High-Risk Women Receiving Tamoxifen or Raloxifene on NSABP P1 and P2 Prevention Trials. A Pharmacogenomics Research Network-RIKEN-NSABP Collaboration Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Pd05-02 |
0.419 |
|
2009 |
Li L, Fridley BL, Kalari K, Jenkins G, Batzler A, Weinshilboum RM, Wang L. Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers. Plos One. 4: e7765. PMID 19898621 DOI: 10.1371/Journal.Pone.0007765 |
0.372 |
|
2009 |
Zhang J, Ji Y, Moon I, Pelleymounter LL, Ezequel Salavaggione O, Wu Y, Jenkins GD, Batzler AJ, Schaid DJ, Weinshilboum RM. Catechol O-methyltransferase pharmacogenomics: human liver genotype-phenotype correlation and proximal promoter studies. Pharmacogenetics and Genomics. 19: 577-87. PMID 19641441 DOI: 10.1097/FPC.0b013e32832c15c6 |
0.304 |
|
2009 |
Feng Q, Keshtgarpour M, Pelleymounter LL, Moon I, Kalari KR, Eckloff BW, Wieben ED, Weinshilboum RM. Human S-adenosylhomocysteine hydrolase: common gene sequence variation and functional genomic characterization. Journal of Neurochemistry. 110: 1806-17. PMID 19619139 DOI: 10.1111/j.1471-4159.2009.06276.x |
0.407 |
|
2009 |
Mrazek DA, Rush AJ, Biernacka JM, O'Kane DJ, Cunningham JM, Wieben ED, Schaid DJ, Drews MS, Courson VL, Snyder KA, Black JL, Weinshilboum RM. SLC6A4 variation and citalopram response. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 341-51. PMID 18618621 DOI: 10.1002/ajmg.b.30816 |
0.346 |
|
2009 |
Goetz M, Suman V, Ames M, Black J, Safgren S, Kuffel M, Avula R, Moyer A, Weinshilboum R, Reynolds C, Perez E, Ingle J. Tamoxifen pharmacogenetics ofCYP2D6, CYP2C19, andSULT1A1: long term follow-up of the North Central Cancer Treatment Group 89-30-52 adjuvant trial. Cancer Research. 69: 6037. DOI: 10.1158/0008-5472.Sabcs-6037 |
0.375 |
|
2009 |
Goetz M, Ames M, Gnant M, Filpits M, Jakesz R, Greil R, Marth C, Samonigg H, Suman V, Safgren S, Kuffel M, Weinshilboum R, Erlander M, Ma X, Ingle J. Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial. Cancer Research. 69: 57. DOI: 10.1158/0008-5472.Sabcs-57 |
0.301 |
|
2008 |
Hebbring SJ, Moyer AM, Weinshilboum RM. Sulfotransferase gene copy number variation: pharmacogenetics and function. Cytogenetic and Genome Research. 123: 205-10. PMID 19287157 DOI: 10.1159/000184710 |
0.646 |
|
2008 |
Schmiegelow K, Forestier E, Kristinsson J, Söderhäll S, Vettenranta K, Weinshilboum R, Wesenberg F. Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. Leukemia. 23: 557-64. PMID 18987654 DOI: 10.1038/Leu.2008.316 |
0.322 |
|
2008 |
Ji Y, Olson J, Zhang J, Hildebrandt M, Wang L, Ingle J, Fredericksen Z, Sellers T, Miller W, Dixon JM, Brauch H, Eichelbaum M, Justenhoven C, Hamann U, Ko Y, ... ... Weinshilboum R, et al. Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Research. 68: 5997-6005. PMID 18632656 DOI: 10.1158/0008-5472.Can-08-0043 |
0.419 |
|
2008 |
Moyer AM, Salavaggione OE, Wu TY, Moon I, Eckloff BW, Hildebrandt MA, Schaid DJ, Wieben ED, Weinshilboum RM. Glutathione s-transferase p1: gene sequence variation and functional genomic studies. Cancer Research. 68: 4791-801. PMID 18559526 DOI: 10.1158/0008-5472.CAN-07-6724 |
0.655 |
|
2008 |
Kocabas NA, Aksoy P, Pelleymounter LL, Moon I, Ryu JS, Gilbert JA, Salavaggione OE, Eckloff BW, Wieben ED, Yee V, Weinshilboum RM, Ames MM. Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1951-9. PMID 18556440 DOI: 10.1124/Dmd.108.020925 |
0.301 |
|
2008 |
Li F, Feng Q, Lee C, Wang S, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Schaid DJ, Yee V, Weinshilboum RM. Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization. Molecular Genetics and Metabolism. 94: 326-35. PMID 18457970 DOI: 10.1016/J.Ymgme.2008.03.013 |
0.367 |
|
2008 |
Ji Y, Snyder EM, Fridley BL, Salavaggione OE, Moon I, Batzler A, Yee VC, Schaid DJ, Joyner MJ, Johnson BD, Weinshilboum RM. Human phenylethanolamine N-methyltransferase genetic polymorphisms and exercise-induced epinephrine release. Physiological Genomics. 33: 323-32. PMID 18349382 DOI: 10.1152/Physiolgenomics.00248.2007 |
0.329 |
|
2007 |
Moyer AM, Salavaggione OE, Hebbring SJ, Moon I, Hildebrandt MA, Eckloff BW, Schaid DJ, Wieben ED, Weinshilboum RM. Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7207-16. PMID 18056202 DOI: 10.1158/1078-0432.Ccr-07-0635 |
0.683 |
|
2007 |
Wang L, Salavaggione E, Pelleymounter L, Eckloff B, Wieben E, Weinshilboum R. Human 3beta-hydroxysteroid dehydrogenase types 1 and 2: Gene sequence variation and functional genomics. The Journal of Steroid Biochemistry and Molecular Biology. 107: 88-99. PMID 17689071 DOI: 10.1016/J.Jsbmb.2007.03.037 |
0.477 |
|
2007 |
Ji Y, Moon I, Zlatkovic J, Salavaggione OE, Thomae BA, Eckloff BW, Wieben ED, Schaid DJ, Weinshilboum RM. Human hydroxysteroid sulfotransferase SULT2B1 pharmacogenomics: gene sequence variation and functional genomics. The Journal of Pharmacology and Experimental Therapeutics. 322: 529-40. PMID 17496163 DOI: 10.1124/jpet.107.122895 |
0.359 |
|
2007 |
Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, et al. Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. Pharmacogenomics. 8: 519. PMID 17465717 DOI: 10.2217/14622416.8.5.519 |
0.304 |
|
2007 |
Hebbring SJ, Adjei AA, Baer JL, Jenkins GD, Zhang J, Cunningham JM, Schaid DJ, Weinshilboum RM, Thibodeau SN. Human SULT1A1 gene: copy number differences and functional implications. Human Molecular Genetics. 16: 463-70. PMID 17189289 DOI: 10.1093/Hmg/Ddl468 |
0.667 |
|
2006 |
Weinshilboum RM. Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase Cellular and Molecular Neurobiology. 26: 539-561. PMID 16807786 |
0.306 |
|
2006 |
Mukherjee B, Salavaggione OE, Pelleymounter LL, Moon I, Eckloff BW, Schaid DJ, Wieben ED, Weinshilboum RM. Glutathione S-transferase omega 1 and omega 2 pharmacogenomics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1237-46. PMID 16638819 DOI: 10.1124/dmd.106.009613 |
0.317 |
|
2006 |
Wang L, Weinshilboum R. Thiopurine S-methyltransferase pharmacogenetics: Insights, challenges and future directions Oncogene. 25: 1629-1638. PMID 16550163 DOI: 10.1038/Sj.Onc.1209372 |
0.371 |
|
2006 |
Martin YN, Salavaggione OE, Eckloff BW, Wieben ED, Schaid DJ, Weinshilboum RM. Human methylenetetrahydrofolate reductase pharmacogenomics: gene resequencing and functional genomics. Pharmacogenetics and Genomics. 16: 265-77. PMID 16538173 DOI: 10.1097/01.fpc.0000194423.20393.08 |
0.404 |
|
2005 |
Ma CX, Adjei AA, Salavaggione OE, Coronel J, Pelleymounter L, Wang L, Eckloff BW, Schaid D, Wieben ED, Adjei AA, Weinshilboum RM. Human aromatase: gene resequencing and functional genomics. Cancer Research. 65: 11071-82. PMID 16322257 DOI: 10.1158/0008-5472.Can-05-1218 |
0.365 |
|
2005 |
Ji Y, Salavaggione OE, Wang L, Adjei AA, Eckloff B, Wieben ED, Weinshilboum RM. Human phenylethanolamine N-methyltransferase pharmacogenomics: gene re-sequencing and functional genomics. Journal of Neurochemistry. 95: 1766-76. PMID 16277617 DOI: 10.1111/J.1471-4159.2005.03453.X |
0.365 |
|
2005 |
Adjei A, Olson J, Vachon C, Vierkant R, Pankratz V, Brandt K, Fredericksen Z, Sellers T, Weinshilboum R. Human sulfotransferase (SULT) 1A1 pharmacogenetics: Intragene haplotype, breast cancer and mammographic breast density Clinical Pharmacology & Therapeutics. 77. DOI: 10.1016/J.Clpt.2004.12.259 |
0.357 |
|
2005 |
HILDEBRANDT M, SALAVAGGIONE O, MARTIN Y, FLYNN H, JALAL S, WIEBEN E, WEINSHILBOUM R. Human sulfotransferase (SULT) 1A3 pharmacogenetics: Gene duplication and functional genomics Clinical Pharmacology & Therapeutics. 77: P23-P23. DOI: 10.1016/J.Clpt.2004.11.090 |
0.473 |
|
2005 |
MA C, ADJEI A, SALAVAGGIONE O, WANG L, ECKLOFF B, WIEBEN E, ADJEI A, WEINSHILBOUM R. Human aromatase (CYP19) pharmacogenomics: Gene resequencing and functional genomics Clinical Pharmacology & Therapeutics. 77: P22-P22. DOI: 10.1016/J.Clpt.2004.11.085 |
0.473 |
|
2004 |
Hildebrandt MA, Salavaggione OE, Martin YN, Flynn HC, Jalal S, Wieben ED, Weinshilboum RM. Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies. Biochemical and Biophysical Research Communications. 321: 870-8. PMID 15358107 DOI: 10.1016/j.bbrc.2004.07.038 |
0.344 |
|
2004 |
Weinshilboum R, Wang L. Pharmacogenomics: Bench to bedside Nature Reviews Drug Discovery. 3: 739-748. PMID 15340384 DOI: 10.1038/Nrd1497 |
0.304 |
|
2004 |
Shield AJ, Thomae BA, Eckloff BW, Wieben ED, Weinshilboum RM. Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes. Molecular Psychiatry. 9: 151-60. PMID 14966473 DOI: 10.1038/Sj.Mp.4001386 |
0.456 |
|
2004 |
Thomae BA, Rifki OF, Theobald MA, Eckloff BW, Wieben ED, Weinshilboum RM. Human catecholamine sulfotransferase (SULT1A3) pharmacogenetics: functional genetic polymorphism. Journal of Neurochemistry. 87: 809-19. PMID 14622112 DOI: 10.1046/j.1471-4159.2003.02027.x |
0.302 |
|
2004 |
Salavaggione OE, Yang C, Kidd LB, Thomae BA, Pankratz VS, Trepanier LA, Weinshilboum RM. Cat red blood cell thiopurine S-methyltransferase: companion animal pharmacogenetics. The Journal of Pharmacology and Experimental Therapeutics. 308: 617-26. PMID 14610243 DOI: 10.1124/Jpet.103.059055 |
0.325 |
|
2004 |
Adjei AA, Thomae BA, Prondzinski JL, Eckloff BW, Wieben ED, Weinshilboum RM. Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics. British Journal of Pharmacology. 139: 1373-82. PMID 12922923 DOI: 10.1038/sj.bjp.0705369 |
0.356 |
|
2003 |
Xu ZH, Thomae BA, Eckloff BW, Wieben ED, Weinshilboum RM. Pharmacogenetics of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1): gene resequencing, sequence variation, and functional genomics. Biochemical Pharmacology. 65: 1787-96. PMID 12781330 DOI: 10.1016/S0006-2952(03)00104-7 |
0.352 |
|
2003 |
Weinshilboum R. Inheritance and drug response New England Journal of Medicine. 348: 529-537. PMID 12571261 DOI: 10.1056/Nejmra020021 |
0.345 |
|
2003 |
Prondzinski J, Thomae B, Wang L, Eckloff B, Wieben E, Weinshilboum R. Sulfotransferase (sult) 1A1 pharmacogenetics: Functional 5′‐flanking region (5′‐FR) polymorphisms Clinical Pharmacology & Therapeutics. 73. DOI: 10.1016/S0009-9236(03)90641-2B |
0.304 |
|
2003 |
Thomae B, Rifki O, Theobald M, Eckloff B, Wieben E, Weinshilboum R. Human Catecholamine Sulfotransferase (SULT1A3) Pharmacogenetics: Common Functional Genetic Polymorphism in African-American Subjects Clinical Pharmacology & Therapeutics. 73: P29-P29. DOI: 10.1016/S0009-9236(03)90462-0 |
0.338 |
|
2002 |
Salavaggione OE, Kidd L, Prondzinski JL, Szumlanski CL, Pankratz VS, Wang L, Trepanier L, Weinshilboum RM. Canine red blood cell thiopurine S-methyltransferase: companion animal pharmacogenetics. Pharmacogenetics. 12: 713-24. PMID 12464800 DOI: 10.1097/00008571-200212000-00005 |
0.343 |
|
2002 |
Wang L, Thomae B, Eckloff B, Wieben E, Weinshilboum R. Human histamine N-methyltransferase pharmacogenetics: Gene resequencing, promoter characterization, and functional studies of a common 5′-flanking region single nucleotide polymorphism (SNP) Biochemical Pharmacology. 64: 699-710. PMID 12167489 DOI: 10.1016/S0006-2952(02)01223-6 |
0.491 |
|
2002 |
Thomae BA, Eckloff BW, Freimuth RR, Wieben ED, Weinshilboum RM. Human sulfotransferase SULT2A1 pharmacogenetics: genotype-to-phenotype studies. The Pharmacogenomics Journal. 2: 48-56. PMID 11990382 DOI: 10.1038/sj.tpj.6500089 |
0.356 |
|
2002 |
Xu ZH, Freimuth RR, Eckloff B, Wieben E, Weinshilboum RM. Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPSS2) pharmacogenetics: gene resequencing, genetic polymorphisms and functional characterization of variant allozymes. Pharmacogenetics. 12: 11-21. PMID 11773860 DOI: 10.1097/00008571-200201000-00003 |
0.371 |
|
2001 |
Freimuth RR, Eckloff B, Wieben ED, Weinshilboum RM. Human sulfotransferase SULT1C1 pharmacogenetics: Gene resequencing and functional genomic studies Pharmacogenetics. 11: 747-756. PMID 11740338 DOI: 10.1097/00008571-200112000-00002 |
0.372 |
|
2001 |
Weinshilboum R. Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyltransferase Drug Metabolism and Disposition. 29: 601-605. PMID 11259360 |
0.335 |
|
2001 |
Freimuth RR, Weinshilboum RM. Human sulfotransferase (SULT) 1C1: Functional genomics of common polymorphisms Clinical Pharmacology and Therapeutics. 69. |
0.32 |
|
2000 |
Yan L, Zhang S, Eiff B, Szumlanski CL, Powers M, O'Brien JF, Weinshilboum RM. Thiopurine methyltransferase polymorphic tandem repeat: genotype-phenotype correlation analysis. Clinical Pharmacology and Therapeutics. 68: 210-9. PMID 10976552 DOI: 10.1067/mcp.2000.108674 |
0.305 |
|
1999 |
Yan L, Otterness DM, Weinshilboum RM. Human nicotinamide N-methyltransferase pharmacogenetics: Gene sequence analysis and promoter characterization Pharmacogenetics. 9: 307-316. PMID 10471062 |
0.337 |
|
1999 |
Raftogianis RB, Wood TC, Weinshilboum RM. Human phenol sulfotransferases SULT1A2 and SULT1A1 Genetic polymorphisms, allozyme properties, and human liver genotype-phenotype correlations Biochemical Pharmacology. 58: 605-616. PMID 10413297 DOI: 10.1016/S0006-2952(99)00145-8 |
0.327 |
|
1999 |
Weinshilboum RM, Otterness DM, Szumlanski CL. Methylation pharmacogenetics: Catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase Annual Review of Pharmacology and Toxicology. 39: 19-52. PMID 10331075 DOI: 10.1146/annurev.pharmtox.39.1.19 |
0.306 |
|
1997 |
Otterness D, Szumlanski C, Lennard L, Klemetsdal B, Aarbakke J, Park‐Hah JO, Iven H, Schmiegelow K, Branum E, O'Brien J, Weinshilboum R. Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms Clinical Pharmacology & Therapeutics. 62: 60-73. PMID 9246020 DOI: 10.1016/S0009-9236(97)90152-1 |
0.433 |
|
1996 |
Wood TC, Her C, Aksoy I, Otterness DM, Weinshilboum RM. Human dehydroepiandrosterone sulfotransferase pharmacogenetics: Quantitative Western analysis and gene sequence polymorphisms Journal of Steroid Biochemistry and Molecular Biology. 59: 467-478. PMID 9010352 DOI: 10.1016/S0960-0760(96)00142-2 |
0.331 |
|
1996 |
Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics. 6: 243-50. PMID 8807664 DOI: 10.1097/00008571-199606000-00007 |
0.3 |
|
1996 |
Aksoy S, Raftogianis R, Weinshilboum R. Human histamine N-methyltransferase gene: Structural characterization and chromosomal localization Biochemical and Biophysical Research Communications. 219: 548-554. PMID 8605025 DOI: 10.1006/Bbrc.1996.0271 |
0.364 |
|
1996 |
Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, Spurr N, Lennard L, Wieben E, Weinshilboum R. Thiopurine Methyltransferase Pharmacogenetics : Human Gene Cloning And Characterization Of A Common Polymorphism Dna and Cell Biology. 15: 17-30. PMID 8561894 DOI: 10.1089/Dna.1996.15.17 |
0.424 |
|
1994 |
Weinshilboum R, Aksoy I. Sulfation pharmacogenetics in humans Chemico-Biological Interactions. 92: 233-246. PMID 8033256 DOI: 10.1016/0009-2797(94)90066-3 |
0.348 |
|
1994 |
Otterness DM, Weinshilboum R. Human dehydroepiandrosterone sulfotransferase: molecular cloning of cDNA and genomic DNA Chemico-Biological Interactions. 92: 145-159. PMID 8033249 DOI: 10.1016/0009-2797(94)90060-4 |
0.331 |
|
1990 |
Boudíková B, Szumlanski C, Maidak B, Weinshilboum R. Human liver catechol-O-methyltransferase pharmacogenetics Clinical Pharmacology and Therapeutics. 48: 381-389. PMID 2225698 DOI: 10.1038/Clpt.1990.166 |
0.333 |
|
1988 |
Weinshilboum R. Pharmacogenetics of methylation: Relationship to drug metabolism Clinical Biochemistry. 21: 201-210. PMID 3044645 DOI: 10.1016/S0009-9120(88)80002-X |
0.31 |
|
1988 |
Weinshilboum R. 1987 CSCC—MedChem Award Recipient Clinical Biochemistry. 21: 199-200. DOI: 10.1016/S0009-9120(88)80001-8 |
0.35 |
|
1987 |
Weinshilboum R. Pharmacogenetics of methyl conjugation and thiopurine drug toxicity Bioessays. 7: 78-82. PMID 3632658 DOI: 10.1002/Bies.950070207 |
0.314 |
|
1984 |
Wilson AF, Elston RC, Siervogel RM, Weinshilboum R, Ward LJ. Linkage relationships between a major gene for catechol-O-methyltransferase activity and 25 polymorphic marker systems American Journal of Medical Genetics. 19: 525-532. PMID 6507499 DOI: 10.1002/Ajmg.1320190314 |
0.35 |
|
1981 |
Weinshilboum R, Dunnette J. Thermal stability and the biochemical genetics of erythrocyte catechol-O-methyl-transferase and plasma dopamine-beta-hydroxylase Clinical Genetics. 19: 426-437. PMID 7296933 DOI: 10.1111/J.1399-0004.1981.Tb00740.X |
0.325 |
|
1979 |
Grzanna R, Nelson MF, Weinshilboum RM, Dunnette J, Coyle JT. Characterization of the basis for differences in serum DBH activity in immature and adult rats by use of homologous antibody. Journal of Neurochemistry. 33: 913-21. PMID 39981 DOI: 10.1111/j.1471-4159.1979.tb09921.x |
0.359 |
|
1977 |
Dunnette J, Weinshilboum R. Inheritance of low immunoreactive human plasma dopamine-β-hydroxylase. Radioimmunoassay studies Journal of Clinical Investigation. 60: 1080-1087. PMID 908751 DOI: 10.1172/Jci108859 |
0.328 |
|
1973 |
Dunner DL, Cohn CK, Weinshilboum RM, Wyatt RJ. The activity of dopamine beta hydroxylase and methionine activating enzyme in blood of schizophrenic patients Biological Psychiatry. 6: 215-220. PMID 4732252 |
0.361 |
|
1972 |
Axelrod J, Weinshilboum R. Catecholamines New England Journal of Medicine. 287: 237-242. PMID 4402575 |
0.318 |
|
1971 |
Weinshilboum R, Axelrod J. Serum dopamine-β-hydroxylase: Decrease after chemical sympathectomy Science. 173: 931-934. PMID 5572168 DOI: 10.1126/Science.173.4000.931 |
0.356 |
|
1971 |
Molinoff PB, Weinshilboum R, Axelrod J. A sensitive enzymatic assay for dopamine- -hydroxylase. The Journal of Pharmacology and Experimental Therapeutics. 178: 425-31. PMID 5571894 |
0.536 |
|
1971 |
Johnson DG, Thoa NB, Weinshilboum R, Axelrod J, Kopin IJ. Enhanced release of dopamine- -hydroxylase from sympathetic nerves by calcium and phenoxybenzamine and its reversal by prostaglandins. Proceedings of the National Academy of Sciences of the United States of America. 68: 2227-30. PMID 5289380 DOI: 10.1073/Pnas.68.9.2227 |
0.32 |
|
1971 |
Weinshilboum RM, Thoa NB, Johnson DG, Kopin IJ, Axelrod J. Proportional release of norepinephrine and dopamine- -hydroxylase from sympathetic nerves. Science (New York, N.Y.). 174: 1349-51. PMID 5135722 DOI: 10.1126/Science.174.4016.1349 |
0.33 |
|
1971 |
Weinshilboum RM, Axelrod J. Reduced plasma dopamine- -hydroxylase activity in familial dysautonomia New England Journal of Medicine. 285: 938-942. PMID 5096225 DOI: 10.1056/Nejm197110212851703 |
0.346 |
|
1971 |
Weinshilboum RM, Kvetnansky R, Axelrod J, Kopin IJ. Elevation of serum dopamine-beta-hydroxylase activity with forced immobilization. Nature: New Biology. 230: 287-8. PMID 4930611 DOI: 10.1038/Newbio230287A0 |
0.367 |
|
1971 |
Weinshilboum R, Axelrod J. Serum dopamine-beta-hydroxylase activity Circulation Research. 28: 307-315. PMID 4925832 DOI: 10.1161/01.Res.28.3.307 |
0.445 |
|
1970 |
Weinshilboum R, Axelrod J. Dopamine-beta-hydroxylase activity in the rat after hypophysectomy Endocrinology. 87: 894-899. PMID 4320638 DOI: 10.1210/Endo-87-5-894 |
0.433 |
|
1970 |
Molinoff PB, Brimijoin S, Weinshilboum R, Axelrod J. Neurally mediated increase in dopamine-beta-hydroxylase activity. Proceedings of the National Academy of Sciences of the United States of America. 66: 453-8. PMID 4317916 DOI: 10.1073/Pnas.66.2.453 |
0.596 |
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