Weihua Guan, Ph.D. - Publications

Affiliations: 
2010 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biostatistics Biology, Genetics

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wielscher M, Mandaviya PR, Kuehnel B, Joehanes R, Mustafa R, Robinson O, Zhang Y, Bodinier B, Walton E, Mishra PP, Schlosser P, Wilson R, Tsai PC, Palaniswamy S, Marioni RE, ... ... Guan W, et al. DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nature Communications. 13: 2408. PMID 35504910 DOI: 10.1038/s41467-022-29792-6  0.302
2022 Holliday KM, Gondalia R, Baldassari A, Justice AE, Stewart JD, Liao D, Yanosky JD, Jordahl KM, Bhatti P, Assimes TL, Pankow JS, Guan W, Fornage M, Bressler J, North KE, et al. Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults. Environmental Research. 113360. PMID 35500859 DOI: 10.1016/j.envres.2022.113360  0.338
2021 Jhun MA, Mendelson M, Wilson R, Gondalia R, Joehanes R, Salfati E, Zhao X, Braun KVE, Do AN, Hedman ÅK, Zhang T, Carnero-Montoro E, Shen J, Bartz TM, Brody JA, ... ... Guan W, et al. A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nature Communications. 12: 3987. PMID 34183656 DOI: 10.1038/s41467-021-23899-y  0.329
2020 Justice AE, Chittoor G, Gondalia R, Melton PE, Lim E, Grove ML, Whitsel EA, Liu CT, Cupples LA, Fernandez-Rhodes L, Guan W, Bressler J, Fornage M, Boerwinkle E, Li Y, et al. Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems. Epigenomics. PMID 32901515 DOI: 10.2217/Epi-2019-0276  0.447
2020 Arthur VL, Guan W, Loza BL, Keating B, Chen J. Joint testing of donor and recipient genetic matching scores and recipient genotype has robust power for finding genes associated with transplant outcomes. Genetic Epidemiology. PMID 32783273 DOI: 10.1002/Gepi.22349  0.339
2020 Colicino E, Marioni R, Ward-Caviness C, Gondalia R, Guan W, Chen B, Tsai PC, Huan T, Xu G, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, et al. Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. Aging. 12. PMID 32697766 DOI: 10.18632/aging.103408  0.338
2020 Karger AB, Steffen BT, Nomura SO, Guan W, Garg PK, Szklo M, Budoff MJ, Tsai MY. Association Between Homocysteine and Vascular Calcification Incidence, Prevalence, and Progression in the MESA Cohort. Journal of the American Heart Association. 9: e013934. PMID 32013703 DOI: 10.1161/Jaha.119.013934  0.302
2020 Gondalia R, Holliday KM, Baldassari A, Justice AE, Stewart JD, Liao D, Yanosky JD, Engel SM, Jordahl KM, Bhatti P, Horvath S, Assimes TL, Pankow JS, Demerath EW, Guan W, et al. Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study. Environmental Health Perspectives. 128: 17004. PMID 31903802 DOI: 10.1289/Ehp5360  0.353
2020 Nguyen S, Guan W, Bressler J, Grove M, Xia R, Wang Z, Fernandez-rhodes LE, Justice AE, Li Y, Whitsel EA, North KE, Fornage M, Boerwinkle E, Pankow JS, Demerath EW. Abstract P272: Associations of an Epigenetic Biomarker of Aging and Healthspan With BMI Status and Metabolic Health in Adult African Americans: The Atherosclerosis Risk in Communities (ARIC) Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P272  0.398
2020 Nguyen S, Guan W, Bressler J, Grove M, Palta P, Xia R, Wang Z, Fernandez-Rhodes L, Justice AE, Li Y, Whitsel EA, North KE, Fornage M, Boerwinkle E, Kucharska-Newton A, et al. Abstract P271: Dna Methylation Measures of Aging in Midlife are Associated With Frailty Components in African American and European American Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P271  0.406
2019 Robinson SL, Mumford SL, Guan W, Zeng X, Kim K, Radoc JG, Trinh MH, Flannagan K, Schisterman EF, Yeung E. Maternal fatty acid concentrations and newborn DNA methylation. The American Journal of Clinical Nutrition. PMID 31858113 DOI: 10.1093/Ajcn/Nqz311  0.3
2019 Tang W, Saratzis A, Pattee J, Smith J, Pankratz N, Leavy OC, Guan W, Dudbridge F, Pankow JS, Kitas GD, Lutsey PL, Bown MJ. Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society For Vascular Surgery. PMID 31680049 DOI: 10.1016/J.Ejvs.2019.02.017  0.345
2019 Bressler J, Marioni RE, Walker RM, Xia R, Gottesman RF, Windham BG, Grove ML, Guan W, Pankow JS, Evans KL, McIntosh AM, Deary IJ, Mosley TH, Boerwinkle E, Fornage M. Epigenetic Age Acceleration and Cognitive Function in African-American Adults in Midlife: The Atherosclerosis Risk in Communities Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 31630168 DOI: 10.1093/Gerona/Glz245  0.315
2019 Huan T, Joehanes R, Song C, Peng F, Guo Y, Mendelson M, Yao C, Liu C, Ma J, Richard M, Agha G, Guan W, Almli LM, Conneely KN, Keefe J, et al. Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease. Nature Communications. 10: 4267. PMID 31537805 DOI: 10.1038/S41467-019-12228-Z  0.542
2019 Gondalia R, Baldassari A, Holliday KM, Justice AE, Méndez-Giráldez R, Stewart JD, Liao D, Yanosky JD, Brennan KJM, Engel SM, Jordahl KM, Kennedy E, Ward-Caviness CK, Wolf K, Waldenberger M, ... ... Guan W, et al. Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation. Environment International. 104723. PMID 31208937 DOI: 10.1016/J.Envint.2019.03.071  0.388
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Guan W, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.317
2019 Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating B, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA. Tacrolimus Troughs and Genetic Determinants of Metabolism in Kidney Transplant Recipients: A comparison of four ancestry groups. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30953600 DOI: 10.1111/Ajt.15385  0.334
2019 Stapleton CP, Heinzel A, Guan W, van der Most PJ, van Setten J, Lord GM, Keating BJ, Israni AK, de Borst MH, Bakker SJL, Snieder H, Weale ME, Delaney F, Hernandez-Fuentes MP, Reindl-Schwaighofer R, et al. The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30920136 DOI: 10.1111/Ajt.15326  0.347
2019 Oetting WS, Wu B, Schladt DP, Guan W, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Transplantation. PMID 30801552 DOI: 10.1097/Tp.0000000000002625  0.368
2019 Oetting WS, Schladt DP, Dorr CR, Wu B, Guan W, Remmel RP, Iklé D, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Analysis of 75 Candidate SNPs Associated with Acute Rejection in Kidney Transplant Recipients: Validation of rs2910164 in MicroRNA MIR146A. Transplantation. PMID 30801535 DOI: 10.1097/Tp.0000000000002659  0.357
2019 Lindström S, Brody JA, Turman C, Germain M, Bartz TM, Smith EN, Chen MH, Puurunen M, Chasman D, Hassler J, Pankratz N, Basu S, Guan W, Gyorgy B, Ibrahim M, et al. A large-scale exome array analysis of venous thromboembolism. Genetic Epidemiology. PMID 30659681 DOI: 10.1002/Gepi.22187  0.376
2019 Nguyen S, Guan W, Bressler J, Grove ML, Xia R, Wang Z, Fernandez-Rhodes L, Justice AE, Li Y, Whitsel EA, North KE, Fornage M, Boerwinkle E, Pankow JS, Demerath EW. Abstract 002: Adherence to Ideal Life’s Simple 7 Metrics is Associated With Epigenetic Biomarkers of Aging in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study Circulation. 139. DOI: 10.1161/Circ.139.Suppl_1.002  0.408
2018 Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK. Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing. The Pharmacogenomics Journal. PMID 30442921 DOI: 10.1038/S41397-018-0063-Z  0.38
2018 Wu C, Park JY, Guan W, Pan W. An adaptive gene-based test for methylation data. Bmc Proceedings. 12: 60. PMID 30275902 DOI: 10.1186/S12919-018-0126-9  0.34
2018 Weng LC, Guan W, Steffen LM, Pankow JS, Pankratz N, Chen MH, Cushman M, Basu S, Folsom AR, Tang W. Pleiotropic effects of n-6 and n-3 fatty acid-related genetic variants on circulating hemostatic variables. Thrombosis Research. 168: 53-59. PMID 29902632 DOI: 10.1016/J.Thromres.2018.05.032  0.334
2018 Scheibner A, Remmel R, Schladt D, Oetting W, Guan W, Wu B, Dorr C, Israni A, Jacobson PA. Tacrolimus Elimination in Four Patients with a CYP3A5*3/*3 CYP3A4*22/*22 Genotype. Pharmacotherapy. PMID 29804290 DOI: 10.1002/Phar.2131  0.3
2018 Dhana K, Braun KVE, Nano J, Voortman T, Demerath EW, Guan W, Fornage M, van Meurs JBJ, Uitterlinden AG, Hofman A, Franco OH, Dehghan A. An Epigenome-Wide Association Study (EWAS) of Obesity-Related Traits. American Journal of Epidemiology. PMID 29762635 DOI: 10.1093/Aje/Kwy025  0.373
2018 Weng LC, Roetker NS, Lutsey PL, Alonso A, Guan W, Pankow JS, Folsom AR, Steffen LM, Pankratz N, Tang W. Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study. Plos One. 13: e0195719. PMID 29649275 DOI: 10.1371/Journal.Pone.0195719  0.313
2018 Thyagarajan B, Guan W, Fedirko V, Barcelo H, Ramasubramaian R, Gross M, Goodman M, Bostick RM. ASSOCIATIONS OF MITOCHONDRIAL POLYMORPHISMS WITH SPORADIC COLORECTAL ADENOMA. Molecular Carcinogenesis. PMID 29323753 DOI: 10.1002/Mc.22783  0.322
2018 Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Dorr C, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients. Pharmacogenomics. PMID 29318894 DOI: 10.2217/Pgs-2017-0187  0.373
2018 Wang X, Pan Y, Zhu H, Hao G, Huang Y, Barnes V, Shi H, Snieder H, Pankow J, North K, Grove M, Guan W, Demerath E, Dong Y, Su S. An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression. Clinical Epigenetics. 10: 3. PMID 29312471 DOI: 10.1186/S13148-017-0435-2  0.355
2018 Dicorpo DA, Lent S, Guan W, Hivert M, Pankow JS. Mendelian Randomization Suggests Causal Influence of Glycemic Traits on DNA Methylation Diabetes. 67. DOI: 10.2337/Db18-1707-P  0.39
2018 WEIR NL, JOHNSON L, GUAN W, STEFFEN B, DJOUSSE L, MUKAMAL KJ, TSAI MY. Cis-Vaccenic Acid Is Associated with Lower HOMA-IR and Incident T2D in Participants from the MESA Cohort Diabetes. 67: 1552-P. DOI: 10.2337/Db18-1552-P  0.322
2018 Israni AK, Jacobson PA, Guan W, Dorr CR, van Setten J, de Borst MH, Stapleton CP, Phelan PJ, Conlon PJ, Birdwell KA, Reindl-Schwaighofer R, Heinzel A, Bakker SJ, Cavelleri G, Oetting WS, et al. Genome-Wide Association Meta-Analysis for Acute Rejection of Kidney Transplants Transplantation. 102: S27. DOI: 10.1097/01.Tp.0000542576.73240.16  0.324
2017 Geurts YM, Dugué PA, Joo JE, Makalic E, Jung CH, Guan W, Nguyen S, Grove ML, Wong EM, Hodge AM, Bassett JK, FitzGerald LM, Tsimiklis H, Baglietto L, Severi G, et al. Novel associations between blood DNA methylation and body mass index in middle-aged and older adults. International Journal of Obesity (2005). PMID 29278407 DOI: 10.1038/Ijo.2017.269  0.35
2017 Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, ... Guan W, et al. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. American Journal of Human Genetics. 101: 888-902. PMID 29198723 DOI: 10.1016/J.Ajhg.2017.09.028  0.461
2017 Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients. The Pharmacogenomics Journal. PMID 29160300 DOI: 10.1038/Tpj.2017.49  0.389
2017 Hu Y, Tanaka T, Zhu J, Guan W, Wu JH, Psaty BM, McKnight B, King IB, Sun Q, Richard M, Manichaikul A, Frazier-Wood AC, Kabagambe EK, Hopkins PN, Ordovas JM, et al. Discovery and fine-mapping of loci associated with monounsaturated fatty acids through trans-ethnic meta-analysis in Chinese and European populations. Journal of Lipid Research. PMID 28298293 DOI: 10.1194/Jlr.P071860  0.353
2017 de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, ... ... Guan W, et al. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. Plos One. 12: e0167742. PMID 28107422 DOI: 10.1371/Journal.Pone.0167742  0.305
2017 Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, et al. Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. Plos Medicine. 14: e1002215. PMID 28095459 DOI: 10.1371/Journal.Pmed.1002215  0.499
2016 Ho YY, Guan W, O'Connell M, Basu S. Powerful association test combining rare variant and gene expression using family data from Genetic Analysis Workshop 19. Bmc Proceedings. 10: 251-255. PMID 27980645 DOI: 10.1186/S12919-016-0039-4  0.362
2016 Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, et al. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. 17: 255. PMID 27955697 DOI: 10.1186/S13059-016-1119-5  0.323
2016 Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, ... ... Guan W, et al. A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry. PMID 27843151 DOI: 10.1038/Mp.2016.192  0.527
2016 Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, et al. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging. PMID 27690265 DOI: 10.18632/aging.101020  0.407
2016 Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, et al. Epigenetic Signatures of Cigarette Smoking. Circulation. Cardiovascular Genetics. PMID 27651444 DOI: 10.1161/Circgenetics.116.001506  0.434
2016 Arora M, Lee SJ, Spellman SR, Weisdorf DJ, Guan W, Haagenson M, Wang T, Horowitz MH, Verneris MR, Fleischhauer K, Hsu K, Thyagarajan B. A Validation Study Failed to Confirm Association Between Genetic Variants in the Base Excision Repair Pathway and TRM and Relapse post HCT. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27155583 DOI: 10.1016/J.Bbmt.2016.04.020  0.337
2016 Zhang G, Huang KC, Xu Z, Tzeng JY, Conneely KN, Guan W, Kang J, Li Y. Across-Platform Imputation of DNA Methylation Levels Incorporating Nonlocal Information Using Penalized Functional Regression. Genetic Epidemiology. PMID 27061717 DOI: 10.1002/Gepi.21969  0.436
2016 Wu J, Li Y, Guan W, Viken K, Perlman DM, Bhargava M. FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis. Human Genetics. PMID 27059607 DOI: 10.1007/S00439-016-1669-3  0.338
2016 Tsai MY, Cao J, Steffen BT, Weir NL, Rich SS, Liang S, Guan W. 5-Lipoxygenase Gene Variants Are Not Associated With Atherosclerosis or Incident Coronary Heart Disease in the Multi-Ethnic Study of Atherosclerosis Cohort. Journal of the American Heart Association. 5. PMID 27025886 DOI: 10.1161/Jaha.115.002814  0.347
2016 Wu C, Demerath EW, Pankow JS, Bressler J, Fornage M, Grove ML, Chen W, Guan W. Imputation of Missing Covariate Values in Epigenome-Wide Analysis of DNA Methylation Data. Epigenetics. 0. PMID 26890800 DOI: 10.1080/15592294.2016.1145328  0.417
2016 Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Samieri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YI, Hernandez DG, Borecki I, Chasman DI, et al. Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. The American Journal of Clinical Nutrition. PMID 26791180 DOI: 10.3945/Ajcn.115.112987  0.385
2015 Sanghavi K, Brundage RC, Miller MB, Schladt DP, Israni AK, Guan W, Oetting WS, Mannon RB, Remmel RP, Matas AJ, Jacobson PA. Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. The Pharmacogenomics Journal. PMID 26667830 DOI: 10.1038/Tpj.2015.87  0.307
2015 Dorajoo R, Sun Y, Han Y, Ke T, Burger A, Chang X, Low HQ, Guan W, Lemaitre RN, Khor CC, Yuan JM, Koh WP, Ong CN, Tai ES, Liu J, et al. A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population. Genes & Nutrition. 10: 53. PMID 26584805 DOI: 10.1007/S12263-015-0502-2  0.314
2015 Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA, et al. Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26485092 DOI: 10.1111/Ajt.13495  0.374
2015 Keating BJ, Setten Jv, Jacobson PA, Holmes MV, Verma SS, Chandrupatla HR, Nair N, Gao H, Li YR, Chang B, Wong C, Phillips R, Cole BS, Mukhtar E, Zhang W, ... ... Guan W, et al. Design and Implementation of the International Genetics and Translational Research in Transplantation Network Transplantation. 99: 2401-2412. PMID 26479416 DOI: 10.1097/Tp.0000000000000913  0.309
2015 Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, ... ... Guan W, et al. Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies. Genome Medicine. 7: 90. PMID 26423053 DOI: 10.1186/S13073-015-0211-X  0.442
2015 Wu B, Pankow JS, Guan W. Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits. Genetic Epidemiology. 39: 399-405. PMID 26282996 DOI: 10.1002/Gepi.21913  0.354
2015 Jia C, Guan W, Yang A, Xiao R, Tang WH, Moravec CS, Margulies KB, Cappola TP, Li M, Li C. MetaDiff: differential isoform expression analysis using random-effects meta-regression. Bmc Bioinformatics. 16: 208. PMID 26134005 DOI: 10.1186/S12859-015-0623-Z  0.455
2015 Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, Sha J, Pankow JS, Liu C, Irvin MR, Fornage M, Hidalgo B, Lin LA, Stanton Thibeault K, Bressler J, et al. Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring, Md.). 23: 1493-1501. PMID 26110892 DOI: 10.1002/Oby.21111  0.503
2015 Wang T, Guan W, Lin J, Boutaoui N, Canino G, Luo J, Celedón JC, Chen W. A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data. Epigenetics : Official Journal of the Dna Methylation Society. 10: 662-669. PMID 26036609 DOI: 10.1080/15592294.2015.1057384  0.368
2015 Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, Hedman ÅK, Sandling JK, Li LA, Irvin MR, Zhi D, Deloukas P, Liang L, Liu C, Bressler J, et al. Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Human Molecular Genetics. PMID 25935004 DOI: 10.1093/Hmg/Ddv161  0.569
2015 Lemaitre RN, King IB, Kabagambe EK, Wu JH, McKnight B, Manichaikul A, Guan W, Sun Q, Chasman DI, Foy M, Wang L, Zhu J, Siscovick DS, Tsai MY, Arnett DK, et al. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. Journal of Lipid Research. 56: 176-84. PMID 25378659 DOI: 10.1194/Jlr.M052456  0.336
2015 Wu B, Guan W. Reader reaction on the generalized Kruskal-Wallis test for genetic association studies incorporating group uncertainty. Biometrics. 71: 556-7. PMID 25351417 DOI: 10.1111/Biom.12260  0.307
2014 Guan W, Li C. Design of DNA pooling to allow incorporation of covariates in rare variants analysis. Plos One. 9: e114523. PMID 25485788 DOI: 10.1371/Journal.Pone.0114523  0.34
2014 Bose M, Wu C, Pankow JS, Demerath EW, Bressler J, Fornage M, Grove ML, Mosley TH, Hicks C, North K, Kao WH, Zhang Y, Boerwinkle E, Guan W. Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study. Bmc Bioinformatics. 15: 312. PMID 25239148 DOI: 10.1186/1471-2105-15-312  0.359
2014 Guan W, Steffen BT, Lemaitre RN, Wu JH, Tanaka T, Manichaikul A, Foy M, Rich SS, Wang L, Nettleton JA, Tang W, Gu X, Bandinelli S, King IB, McKnight B, et al. Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Circulation. Cardiovascular Genetics. 7: 321-31. PMID 24823311 DOI: 10.1161/Circgenetics.113.000208  0.306
2014 Wu J, Lin R, Huang J, Guan W, Oetting WS, Sriramarao P, Blumenthal MN. Functional Fcgamma receptor polymorphisms are associated with human allergy. Plos One. 9: e89196. PMID 24586589 DOI: 10.1371/Journal.Pone.0089196  0.307
2014 Oetting WS, Guan W, Schladt DP, Wildebush WA, Becker J, Thyagarajan B, Jacobson PA, Matas AJ, Israni AK. Telomere length of recipients and living kidney donors and chronic graft dysfunction in kidney transplants. Transplantation. 97: 325-9. PMID 24492422 DOI: 10.1097/01.Tp.0000436705.87898.88  0.335
2013 Thyagarajan B, Arora M, Guan W, Barcelo H, Jackson S, Kumar S, Gertz M. Genetic variants in DNA repair pathways are not associated with disease progression among multiple myeloma patients. Leukemia Research. 37: 1527-31. PMID 24129343 DOI: 10.1016/J.Leukres.2013.07.012  0.345
2013 Israni AK, Riad SM, Leduc R, Oetting WS, Guan W, Schladt D, Matas AJ, Jacobson PA. Tacrolimus trough levels after month 3 as a predictor of acute rejection following kidney transplantation: a lesson learned from DeKAF Genomics. Transplant International : Official Journal of the European Society For Organ Transplantation. 26: 982-9. PMID 23879408 DOI: 10.1111/Tri.12155  0.316
2013 Wu JH, Lemaitre RN, Manichaikul A, Guan W, Tanaka T, Foy M, Kabagambe EK, Djousse L, Siscovick D, Fretts AM, Johnson C, King IB, Psaty BM, McKnight B, Rich SS, et al. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Circulation. Cardiovascular Genetics. 6: 171-83. PMID 23362303 DOI: 10.1161/Circgenetics.112.964619  0.336
2013 Israni AK, Leduc R, Jacobson PA, Wildebush W, Guan W, Schladt D, Matas AJ, Oetting WS. Inflammation in the setting of chronic allograft dysfunction post-kidney transplant: phenotype and genotype. Clinical Transplantation. 27: 348-58. PMID 23350966 DOI: 10.1111/Ctr.12074  0.34
2013 Zhang Y, Guan W, Pan W. Adjustment for population stratification via principal components in association analysis of rare variants. Genetic Epidemiology. 37: 99-109. PMID 23065775 DOI: 10.1002/Gepi.21691  0.321
2012 Oetting WS, Guan W, Schladt DP, Leduc RE, Jacobson PA, Matas AJ, Chinnakotla S, Schröppel B, Murphy BT, Israni AK. Donor polymorphisms of toll-like receptor 4 associated with graft failure in liver transplant recipients. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 18: 1399-405. PMID 22987288 DOI: 10.1002/Lt.23549  0.343
2012 Guan W, Boehnke M, Pluzhnikov A, Cox NJ, Scott LJ. Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes. Genetic Epidemiology. 36: 820-8. PMID 22865662 DOI: 10.1002/Gepi.21668  0.373
2012 Jacobson PA, Schladt D, Israni A, Oetting WS, Lin YC, Leduc R, Guan W, Lamba V, Matas AJ. Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium. Transplantation. 93: 624-31. PMID 22334041 DOI: 10.1097/Tp.0B013E3182461288  0.308
2011 Oetting WS, Schladt DP, Leduc RE, Jacobson PA, Guan W, Matas AJ, Israni A. Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort. Transplant International : Official Journal of the European Society For Organ Transplantation. 24: 1231-8. PMID 21955043 DOI: 10.1111/J.1432-2277.2011.01359.X  0.384
2011 Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI, Rietschel M, Blackwood D, Corvin A, Flickinger M, Guan W, Mattingsdal M, McQuillin A, et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 Nature Genetics. 43: 977-985. PMID 21926972 DOI: 10.1038/Ng.943  0.311
2011 Jacobson PA, Oetting WS, Brearley AM, Leduc R, Guan W, Schladt D, Matas AJ, Lamba V, Julian BA, Mannon RB, Israni A. Novel polymorphisms associated with tacrolimus trough concentrations: results from a multicenter kidney transplant consortium. Transplantation. 91: 300-8. PMID 21206424 DOI: 10.1097/Tp.0B013E318200E991  0.322
2010 Israni A, Leduc R, Holmes J, Jacobson PA, Lamba V, Guan W, Schladt D, Chen J, Matas AJ, Oetting WS. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. Transplantation. 90: 1401-8. PMID 21085059 DOI: 10.1097/Tp.0B013E3182000085  0.363
2010 Israni A, Leduc R, Jacobson P, Schladt D, Guan W, Oetting W, Matas A. CLINICAL FACTORS AND SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH CHRONIC ALLOGRAFT DYSFUNCTION POST-KIDNEY TRANSPLANT Transplantation Journal. 90: 246. DOI: 10.1097/00007890-201007272-00466  0.309
2010 Israni A, Leduc R, Jacobson P, Schladt D, Guan W, Oetting W, Matas A. SINGLE NUCLEOTIDE POLYMORPHISM ASSOCIATED WITH SEVERITY OF ACUTE REJECTION ON KIDNEY ALLOGRAFT BIOPSIES Transplantation Journal. 90: 244. DOI: 10.1097/00007890-201007272-00461  0.307
2009 Scott LJ, Muglia P, Kong XQ, Guan W, Flickinger M, Upmanyu R, Tozzi F, Li JZ, Burmeister M, Absher D, Thompson RC, Francks C, Meng F, Antoniades A, Southwick AM, et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America. 106: 7501-6. PMID 19416921 DOI: 10.1073/Pnas.0813386106  0.361
2009 Guan W, Liang L, Boehnke M, Abecasis GR. Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies. Genetic Epidemiology. 33: 508-17. PMID 19170134 DOI: 10.1002/Gepi.20403  0.609
2008 Li M, Li C, Guan W. Evaluation of coverage variation of SNP chips for genome-wide association studies. European Journal of Human Genetics : Ejhg. 16: 635-43. PMID 18253166 DOI: 10.1038/Sj.Ejhg.5202007  0.508
2007 Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES, Frazer KA, Ballinger DG, ... ... Guan W, et al. Genome-wide detection and characterization of positive selection in human populations. Nature. 449: 913-8. PMID 17943131 DOI: 10.1038/Nature06250  0.53
2007 Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, ... ... Guan W, et al. A second generation human haplotype map of over 3.1 million SNPs. Nature. 449: 851-61. PMID 17943122 DOI: 10.1038/Nature06258  0.541
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