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Stuart A Aaronson, M.D. - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Biochemistry
Website:
http://icahn.mssm.edu/profiles/stuart-a-aaronson
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394 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Adamopoulos C, Ahmed TA, Karoulia Z, Wu X, Sachidanandam R, Aaronson SA, Poulikakos PI. Abstract LB-119: SHP2 drives adaptive resistance to ERK signaling inhibition in molecularly defined subsets of ERK-dependent tumors Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-119  0.314
2018 Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, Moran T, Flavell R, Aaronson S, Hu HM, Arase H, et al. Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity. The Journal of Clinical Investigation. PMID 30352428 DOI: 10.1172/Jci97570  0.347
2017 Pappas K, Xu J, Zairis S, Resnick-Silverman L, Abate F, Steinbach N, Ozturk S, Saal LH, Su T, Cheung P, Schmidt H, Aaronson SA, Hibshoosh H, Manfredi JJ, Rabadan R, et al. p53 maintains baseline expression of multiple tumor suppressor genes. Molecular Cancer Research : McR. PMID 28483946 DOI: 10.1158/1541-7786.Mcr-17-0089  0.364
2016 Muñoz-Fontela C, Mandinova A, Aaronson SA, Lee SW. Emerging roles of p53 and other tumour-suppressor genes in immune regulation. Nature Reviews. Immunology. PMID 27667712 DOI: 10.1038/Nri.2016.99  0.335
2016 Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW. RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress. Current Biology : Cb. 26: 2221-2222. PMID 27554646 DOI: 10.1016/J.Cub.2016.07.072  0.307
2016 Troilo A, Benson EK, Esposito D, Garibsingh RA, Reddy EP, Mungamuri SK, Aaronson SA. Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations. Oncotarget. PMID 27144834 DOI: 10.18632/Oncotarget.9117  0.335
2016 Mungamuri SK, Qiao RF, Yao S, Manfredi JJ, Gu W, Aaronson SA. USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation. Cell Reports. PMID 26971997 DOI: 10.1016/J.Celrep.2016.02.049  0.335
2016 Guernet A, Cartier D, Mungamuri SK, Adriouch S, Vezain M, Charbonnier F, Coutant S, Yao S, Ainani H, Alexandre D, Boyer O, Aaronson SA, Anouar Y, Grumolato L. Abstract PR10: Functional analysis of oncogenic driver mutations in human cancer cells through CRISPR-barcoding Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-Pr10  0.349
2015 Jayaprakash AD, Benson EK, Gone S, Liang R, Shim J, Lambertini L, Toloue MM, Wigler M, Aaronson SA, Sachidanandam R. Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA. Nucleic Acids Research. 43: 2177-87. PMID 25653158 DOI: 10.1093/Nar/Gkv052  0.325
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  0.317
2015 Mungamuri SK, Wang S, Manfredi JJ, Gu W, Aaronson SA. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene. 34: 2461-70. PMID 25023704 DOI: 10.1038/Onc.2014.198  0.346
2014 Benson EK, Mungamuri SK, Attie O, Kracikova M, Sachidanandam R, Manfredi JJ, Aaronson SA. p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes. Oncogene. 33: 3959-69. PMID 24096481 DOI: 10.1038/Onc.2013.378  0.774
2013 Ide T, Brown-Endres L, Chu K, Ongusaha PP, Ohtsuka T, El-Deiry WS, Aaronson SA, Lee SW. Retraction notice to: GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress [Molecular Cell 36, November 13 379-392 (2009)] Molecular Cell. 51. PMID 24137726 DOI: 10.1016/J.Molcel.2013.08.005  0.305
2013 Hamard PJ, Barthelery N, Hogstad B, Mungamuri SK, Tonnessen CA, Carvajal LA, Senturk E, Gillespie V, Aaronson SA, Merad M, Manfredi JJ. The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo. Genes & Development. 27: 1868-85. PMID 24013501 DOI: 10.1101/Gad.224386.113  0.389
2013 Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA. β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors. Plos Genetics. 9: e1003603. PMID 23966864 DOI: 10.1371/Journal.Pgen.1003603  0.396
2013 Kracikova M, Akiri G, George A, Sachidanandam R, Aaronson SA. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell Death and Differentiation. 20: 576-88. PMID 23306555 DOI: 10.1038/Cdd.2012.155  0.785
2013 Kracikova M, Akiri G, Aaronson SA. Abstract B28: Pro-survival role of p53 in regulating epidermal differentiation Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B28  0.789
2013 Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Youssef A, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA. Abstract A02: Beta-catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A02  0.37
2012 Brown-Endres L, Schoenfeld D, Tian F, Kim HG, Namba T, Muñoz-Fontela C, Mandinova A, Aaronson SA, Lee SW. Expression of the p53 target CDIP correlates with sensitivity to TNFα-induced apoptosis in cancer cells. Cancer Research. 72: 2373-82. PMID 22549949 DOI: 10.1158/0008-5472.Can-11-3369  0.354
2012 Mungamuri SK, Benson EK, Wang S, Gu W, Lee SW, Aaronson SA. p53-mediated heterochromatin reorganization regulates its cell fate decisions. Nature Structural & Molecular Biology. 19: 478-84, S1. PMID 22466965 DOI: 10.1038/Nsmb.2271  0.329
2012 Ongusaha P, Kim H, Boswell S, Ridley A, Der C, Dotto G, Kim Y, Aaronson S, Lee S. RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress Current Biology. 22: 2186-2187. DOI: 10.1016/J.Cub.2012.11.007  0.307
2011 Muñoz-Fontela C, Pazos M, Delgado I, Murk W, Mungamuri SK, Lee SW, García-Sastre A, Moran TM, Aaronson SA. p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus. Journal of Immunology (Baltimore, Md. : 1950). 187: 6428-36. PMID 22105999 DOI: 10.4049/Jimmunol.1101459  0.358
2011 Dai C, Tang Y, Jung SY, Qin J, Aaronson SA, Gu W. Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90. Proceedings of the National Academy of Sciences of the United States of America. 108: 18937-42. PMID 22084066 DOI: 10.1073/Pnas.1110988108  0.35
2011 Muñoz-Fontela C, González D, Marcos-Villar L, Campagna M, Gallego P, González-Santamaría J, Herranz D, Gu W, Serrano M, Aaronson SA, Rivas C. Acetylation is indispensable for p53 antiviral activity. Cell Cycle (Georgetown, Tex.). 10: 3701-5. PMID 22033337 DOI: 10.4161/Cc.10.21.17899  0.387
2011 Vijayakumar S, Liu G, Rus IA, Yao S, Chen Y, Akiri G, Grumolato L, Aaronson SA. High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A. Cancer Cell. 19: 601-12. PMID 21575861 DOI: 10.1016/J.Ccr.2011.03.010  0.354
2011 Kim HG, Hwang SY, Aaronson SA, Mandinova A, Lee SW. DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation. The Journal of Biological Chemistry. 286: 17672-81. PMID 21398698 DOI: 10.1074/Jbc.M111.236612  0.387
2010 Rivas C, Aaronson SA, Munoz-Fontela C. Dual Role of p53 in Innate Antiviral Immunity. Viruses. 2: 298-313. PMID 21994612 DOI: 10.3390/V2010298  0.406
2010 Grumolato L, Liu G, Mong P, Mudbhary R, Biswas R, Arroyave R, Vijayakumar S, Economides AN, Aaronson SA. Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. Genes & Development. 24: 2517-30. PMID 21078818 DOI: 10.1101/Gad.1957710  0.312
2010 Asciutti S, Akiri G, Grumolato L, Vijayakumar S, Aaronson SA. Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells. Oncogene. 30: 956-66. PMID 21042278 DOI: 10.1038/Onc.2010.475  0.369
2010 Singh J, Aaronson SA, Mlodzik M. Drosophila Abelson kinase mediates cell invasion and proliferation through two distinct MAPK pathways. Oncogene. 29: 4033-45. PMID 20453880 DOI: 10.1038/Onc.2010.155  0.36
2010 Ide T, Chu K, Aaronson SA, Lee SW. GAMT joins the p53 network: branching into metabolism. Cell Cycle (Georgetown, Tex.). 9: 1706-10. PMID 20404548 DOI: 10.4161/Cc.9.9.11473  0.322
2010 Carrera S, de Verdier PJ, Khan Z, Zhao B, Mahale A, Bowman KJ, Zainol M, Jones GD, Lee SW, Aaronson SA, Macip S. Protection of cells in physiological oxygen tensions against DNA damage-induced apoptosis. The Journal of Biological Chemistry. 285: 13658-65. PMID 20228054 DOI: 10.1074/Jbc.M109.062562  0.312
2010 Lopez-Bergami P, Kim H, Dewing A, Goydos J, Aaronson S, Ronai Z. c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesis. The Journal of Biological Chemistry. 285: 903-13. PMID 19910471 DOI: 10.1074/Jbc.M109.075630  0.331
2009 Ide T, Brown-Endres L, Chu K, Ongusaha PP, Ohtsuka T, El-Deiry WS, Aaronson SA, Lee SW. GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress. Molecular Cell. 36: 379-92. PMID 19917247 DOI: 10.1016/J.Molcel.2009.09.031  0.34
2009 Akiri G, Cherian MM, Vijayakumar S, Liu G, Bafico A, Aaronson SA. Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma. Oncogene. 28: 2163-72. PMID 19377513 DOI: 10.1038/Onc.2009.82  0.3
2009 Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death and Differentiation. 16: 1093-107. PMID 19373242 DOI: 10.1038/Cdd.2009.44  0.307
2009 Liu G, Vijayakumar S, Grumolato L, Arroyave R, Qiao H, Akiri G, Aaronson SA. Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells. The Journal of Cell Biology. 185: 67-75. PMID 19349579 DOI: 10.1083/Jcb.200810137  0.311
2009 Benson EK, Aaronson SA. Abstract A60: Role of telomere dysfunction in the premature cellular senescence of Hutchinson‐Gilford progeria syndrome Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A60  0.328
2009 Kracikova M, Akiri G, Geroge A, Sachidanandam R, Aaronson SA. Abstract A53: Dose‐dependent levels of p53 mediate different cell fate decisions in human mammary epithelial cells Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A53  0.791
2008 Ongusaha PP, Qi HH, Raj L, Kim YB, Aaronson SA, Davis RJ, Shi Y, Liao JK, Lee SW. Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Science Signaling. 1: ra14. PMID 19036714 DOI: 10.1126/Scisignal.1161938  0.314
2008 Muñoz-Fontela C, Macip S, Martínez-Sobrido L, Brown L, Ashour J, García-Sastre A, Lee SW, Aaronson SA. Transcriptional role of p53 in interferon-mediated antiviral immunity. The Journal of Experimental Medicine. 205: 1929-38. PMID 18663127 DOI: 10.1084/Jem.20080383  0.39
2008 Mahale AM, Khan ZA, Igarashi M, Nanjangud GJ, Qiao RF, Yao S, Lee SW, Aaronson SA. Clonal selection in malignant transformation of human fibroblasts transduced with defined cellular oncogenes. Cancer Research. 68: 1417-26. PMID 18316605 DOI: 10.1158/0008-5472.Can-07-3021  0.372
2008 Das S, Boswell SA, Aaronson SA, Lee SW. P53 promoter selection: choosing between life and death. Cell Cycle (Georgetown, Tex.). 7: 154-7. PMID 18212532 DOI: 10.4161/Cc.7.2.5236  0.376
2007 Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson SA, Lee SW. Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation. Cell. 130: 624-37. PMID 17719541 DOI: 10.1016/J.Cell.2007.06.013  0.382
2007 Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. The Embo Journal. 26: 3410-22. PMID 17599062 DOI: 10.1038/Sj.Emboj.7601779  0.342
2007 Liu XH, Kirschenbaum A, Yao S, Liu G, Aaronson SA, Levine AC. Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells. Cancer Research. 67: 5747-53. PMID 17575141 DOI: 10.1158/0008-5472.Can-07-0478  0.341
2007 Lopez-Bergami P, Huang C, Goydos JS, Yip D, Bar-Eli M, Herlyn M, Smalley KS, Mahale A, Eroshkin A, Aaronson S, Ronai Z. Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell. 11: 447-60. PMID 17482134 DOI: 10.1016/J.Ccr.2007.03.009  0.331
2006 Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW. RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Current Biology : Cb. 16: 2466-72. PMID 17174923 DOI: 10.1016/J.Cub.2006.10.056  0.34
2006 Das S, Ongusaha PP, Yang YS, Park JM, Aaronson SA, Lee SW. Discoidin domain receptor 1 receptor tyrosine kinase induces cyclooxygenase-2 and promotes chemoresistance through nuclear factor-kappaB pathway activation. Cancer Research. 66: 8123-30. PMID 16912190 DOI: 10.1158/0008-5472.Can-06-1215  0.356
2006 Macip S, Kosoy A, Lee SW, O'Connell MJ, Aaronson SA. Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint Oncogene. 25: 6037-6047. PMID 16652144 DOI: 10.1038/Sj.Onc.1209629  0.356
2005 Hall CL, Bafico A, Dai J, Aaronson SA, Keller ET. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Research. 65: 7554-60. PMID 16140917 DOI: 10.1158/0008-5472.Can-05-1317  0.306
2005 Manfredi JJ, Dong J, Liu WJ, Resnick-Silverman L, Qiao R, Chahinian P, Saric M, Gibbs AR, Phillips JI, Murray J, Axten CW, Nolan RP, Aaronson SA. Evidence against a role for SV40 in human mesothelioma. Cancer Research. 65: 2602-9. PMID 15805256 DOI: 10.1158/0008-5472.Can-04-2461  0.371
2005 Aaronson S. Teaching resources. Growth factor and receptor tyrosine kinases. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr6. PMID 15728427 DOI: 10.1126/Stke.2722005Tr6  0.3
2004 Bafico A, Liu G, Goldin L, Harris V, Aaronson SA. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell. 6: 497-506. PMID 15542433 DOI: 10.1016/J.Ccr.2004.09.032  0.334
2004 Ohtsuka T, Ryu H, Minamishima YA, Macip S, Sagara J, Nakayama KI, Aaronson SA, Lee SW. ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway. Nature Cell Biology. 6: 121-8. PMID 14730312 DOI: 10.1038/Ncb1087  0.305
2003 Macip S, Igarashi M, Berggren P, Yu J, Lee SW, Aaronson SA. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Molecular and Cellular Biology. 23: 8576-85. PMID 14612402 DOI: 10.1128/Mcb.23.23.8576-8585.2003  0.369
2003 Liu G, Bafico A, Harris VK, Aaronson SA. A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Molecular and Cellular Biology. 23: 5825-35. PMID 12897152 DOI: 10.1128/Mcb.23.16.5825-5835.2003  0.315
2003 Ongusaha PP, Kim Ji, Fang L, Wong TW, Yancopoulos GD, Aaronson SA, Lee SW. p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop Embo Journal. 22: 1289-1301. PMID 12628922 DOI: 10.1093/Emboj/Cdg129  0.377
2002 Han JA, Kim JI, Ongusaha PP, Hwang DH, Ballou LR, Mahale A, Aaronson SA, Lee SW. p53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis Embo Journal. 21: 5635-5644. PMID 12411481 DOI: 10.1093/Emboj/Cdf591  0.384
2002 Ramanathan Y, Zhang H, Aris V, Soteropoulos P, Aaronson SA, Tolias PP. Functional cloning, sorting, and expression profiling of nucleic acid-binding proteins. Genome Research. 12: 1175-84. PMID 12176925 DOI: 10.1101/Gr.156002  0.357
2002 Spiegelman VS, Tang W, Chan AM, Igarashi M, Aaronson SA, Sassoon DA, Katoh M, Slaga TJ, Fuchs SY. Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling. The Journal of Biological Chemistry. 277: 36624-30. PMID 12151397 DOI: 10.1074/Jbc.M204524200  0.387
2002 Macip S, Igarashi M, Fang L, Chen A, Pan ZQ, Lee SW, Aaronson SA. Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. The Embo Journal. 21: 2180-8. PMID 11980715 DOI: 10.1093/Emboj/21.9.2180  0.38
2001 Fang L, Li G, Liu G, Lee SW, Aaronson SA. p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades. The Embo Journal. 20: 1931-9. PMID 11296226 DOI: 10.1093/Emboj/20.8.1931  0.417
2000 Arizti P, Fang L, Park I, Yin Y, Solomon E, Ouchi T, Aaronson SA, Lee SW. Tumor suppressor p53 is required to modulate BRCA1 expression. Molecular and Cellular Biology. 20: 7450-9. PMID 11003642 DOI: 10.1128/Mcb.20.20.7450-7459.2000  0.389
2000 Lee SW, Fang L, Igarashi M, Ouchi T, Lu KP, Aaronson SA. Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53. Proceedings of the National Academy of Sciences of the United States of America. 97: 8302-5. PMID 10890907 DOI: 10.1073/Pnas.150024397  0.398
2000 Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM. Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 5208-13. PMID 10792030 DOI: 10.1073/Pnas.080469697  0.339
2000 Lee SW, Reimer CL, Fang L, Iruela-Arispe ML, Aaronson SA. Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression. Molecular and Cellular Biology. 20: 1723-32. PMID 10669749 DOI: 10.1128/Mcb.20.5.1723-1732.2000  0.349
1999 Fang L, Lee SW, Aaronson SA. Comparative analysis of p73 and p53 regulation and effector functions. The Journal of Cell Biology. 147: 823-30. PMID 10562283 DOI: 10.1083/Jcb.147.4.823  0.389
1999 Blaho JA, Aaronson SA. Convicting a human tumor virus: Guilt by association? Proceedings of the National Academy of Sciences of the United States of America. 96: 7619-7621. PMID 10393867 DOI: 10.1073/Pnas.96.14.7619  0.321
1999 Fedi P, Bafico A, Nieto Soria A, Burgess WH, Miki T, Bottaro DP, Kraus MH, Aaronson SA. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. The Journal of Biological Chemistry. 274: 19465-72. PMID 10383463 DOI: 10.1074/Jbc.274.27.19465  0.7
1999 Fang L, Igarashi M, Leung J, Sugrue MM, Lee SW, Aaronson SA. p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene. 18: 2789-97. PMID 10362249 DOI: 10.1038/Sj.Onc.1202615  0.425
1999 Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. The Journal of Biological Chemistry. 274: 16180-7. PMID 10347172 DOI: 10.1074/Jbc.274.23.16180  0.311
1999 Reimer CL, Borras AM, Kurdistani SK, Garreau JR, Chung M, Aaronson SA, Lee SW. Altered regulation of cyclin G in human breast cancer and its specific localization at replication foes in response to DNA damage in p53+/+ cells Journal of Biological Chemistry. 274: 11022-11029. PMID 10196184 DOI: 10.1074/Jbc.274.16.11022  0.353
1998 Marmorstein LY, Ouchi T, Aaronson SA. The BRCA2 gene product functionally interacts with p53 and RAD51. Proceedings of the National Academy of Sciences of the United States of America. 95: 13869-74. PMID 9811893 DOI: 10.1073/Pnas.95.23.13869  0.369
1998 Bafico A, Gazit A, Wu-Morgan SS, Yaniv A, Aaronson SA. Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts. Oncogene. 16: 2819-25. PMID 9652750 DOI: 10.1038/Sj.Onc.1201797  0.358
1998 Igarashi M, Finch PW, Aaronson SA. Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7). The Journal of Biological Chemistry. 273: 13230-5. PMID 9582367 DOI: 10.1074/Jbc.273.21.13230  0.359
1998 Ouchi T, Monteiro AN, August A, Aaronson SA, Hanafusa H. BRCA1 regulates p53-dependent gene expression. Proceedings of the National Academy of Sciences of the United States of America. 95: 2302-6. PMID 9482880 DOI: 10.1073/Pnas.95.5.2302  0.344
1997 Kirschenbaum A, Wang JP, Ren M, Schiff JD, Aaronson SA, Droller MJ, Ferrara N, Holland JF, Levine AC. Inhibition of vascular endothelial cell growth factor suppresses the in vivo growth of human prostate tumors. Urologic Oncology. 3: 3-10. PMID 21227046 DOI: 10.1016/S1078-1439(97)00001-X  0.318
1997 Sugrue MM, Shin DY, Lee SW, Aaronson SA. Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proceedings of the National Academy of Sciences of the United States of America. 94: 9648-53. PMID 9275177 DOI: 10.1073/Pnas.94.18.9648  0.396
1997 Shin DY, Ishibashi T, Choi TS, Chung E, Chung IY, Aaronson SA, Bottaro DP. A novel human ERK phosphatase regulates H-ras and v-raf signal transduction. Oncogene. 14: 2633-9. PMID 9178761 DOI: 10.1038/Sj.Onc.1201106  0.684
1997 Takayama H, LaRochelle WJ, Sharp R, Otsuka T, Kriebel P, Anver M, Aaronson SA, Merlino G. Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proceedings of the National Academy of Sciences of the United States of America. 94: 701-6. PMID 9012848 DOI: 10.1073/Pnas.94.2.701  0.389
1996 Tachibana M, Takeda K, Nobukuni Y, Urabe K, Long JE, Meyers KA, Aaronson SA, Miki T. Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics. Nature Genetics. 14: 50-4. PMID 8782819 DOI: 10.1038/Ng0996-50  0.372
1996 Cioce V, Csaky KG, Chan AM, Bottaro DP, Taylor WG, Jensen R, Aaronson SA, Rubin JS. Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity. The Journal of Biological Chemistry. 271: 13110-5. PMID 8662798 DOI: 10.1074/Jbc.271.22.13110  0.78
1996 Miki T, Aaronson SA. Isolation of oncogenes by expression cDNA cloning. Methods in Enzymology. 254: 196-206. PMID 8531686 DOI: 10.1016/0076-6879(95)54015-6  0.373
1995 Aroca P, Bottaro DP, Ishibashi T, Aaronson SA, Santos E. Human dual specificity phosphatase VHR activates maturation promotion factor and triggers meiotic maturation in Xenopus oocytes. The Journal of Biological Chemistry. 270: 14229-34. PMID 7775484 DOI: 10.1074/Jbc.270.23.14229  0.678
1995 LaRochelle WJ, Dirsch OR, Finch PW, Cheon HG, May M, Marchese C, Pierce JH, Aaronson SA. Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera. The Journal of Cell Biology. 129: 357-66. PMID 7721940 DOI: 10.1083/Jcb.129.2.357  0.389
1995 Marchese C, Chedid M, Dirsch OR, Csaky KG, Santanelli F, Latini C, LaRochelle WJ, Torrisi MR, Aaronson SA. Modulation of keratinocyte growth factor and its receptor in reepithelializing human skin. The Journal of Experimental Medicine. 182: 1369-76. PMID 7595207 DOI: 10.1084/Jem.182.5.1369  0.312
1994 Cheon HG, LaRochelle WJ, Bottaro DP, Burgess WH, Aaronson SA. High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains. Proceedings of the National Academy of Sciences of the United States of America. 91: 989-93. PMID 8302878 DOI: 10.1073/Pnas.91.3.989  0.664
1994 Alarid ET, Rubin JS, Young P, Chedid M, Ron D, Aaronson SA, Cunha GR. Keratinocyte growth factor functions in epithelial induction during seminal vesicle development Proceedings of the National Academy of Sciences of the United States of America. 91: 1074-1078. PMID 8302834 DOI: 10.1073/Pnas.91.3.1074  0.359
1994 Goldstein DJ, Li W, Wang LM, Heidaran MA, Aaronson S, Shinn R, Schlegel R, Pierce JH. The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the β-type receptor for the platelet-derived growth factor but not other related tyrosine kinase-containing receptors to induce cellular transformation Journal of Virology. 68: 4432-4441. PMID 8207816 DOI: 10.1128/Jvi.68.7.4432-4441.1994  0.342
1994 Aaronson SA, Miki T, Meyers K, Chan A. Growth factors and malignant transformation. Advances in Experimental Medicine and Biology. 348: 7-22. PMID 8172024 DOI: 10.1007/978-1-4615-2942-2_1  0.339
1994 Koji T, Chedid M, Rubin JS, Slayden OD, Csaky KG, Aaronson SA, Brenner RM. Progesterone-dependent expression of keratinocyte growth factor mRNA in stromal cells of the primate endometrium: Keratinocyte growth factor as a progestomedin Journal of Cell Biology. 125: 393-401. PMID 8163555 DOI: 10.1083/Jcb.125.2.393  0.37
1994 Chan AM, Miki T, Meyers KA, Aaronson SA. A human oncogene of the RAS superfamily unmasked by expression cDNA cloning. Proceedings of the National Academy of Sciences of the United States of America. 91: 7558-62. PMID 8052619 DOI: 10.1073/Pnas.91.16.7558  0.36
1994 Strain AJ, Mcguinness G, Rubin JS, Aaronson SA. Keratinocyte growth factor and fibroblast growth factor action on DNA synthesis in rat and human hepatocytes: Modulation by heparin Experimental Cell Research. 210: 253-259. PMID 7507851 DOI: 10.1006/Excr.1994.1037  0.337
1994 Beeler JF, LaRochelle WJ, Chedid M, Tronick SR, Aaronson SA. Prokaryotic expression cloning of a novel human tyrosine kinase. Molecular and Cellular Biology. 14: 982-8. PMID 7507208 DOI: 10.1128/Mcb.14.2.982  0.32
1993 Kraus MH, Fedi P, Starks V, Muraro R, Aaronson SA. Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 2900-4. PMID 8464905 DOI: 10.1073/Pnas.90.7.2900  0.391
1993 Chan AM, Fleming TP, McGovern ES, Chedid M, Miki T, Aaronson SA. Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product. Molecular and Cellular Biology. 13: 762-8. PMID 8423800 DOI: 10.1128/Mcb.13.2.762  0.343
1993 Suzuki M, Itoh T, Osada H, Rubin JS, Aaronson SA, Suzuki T, Koga N, Saito T, Mitsui Y. Spleen-derived growth factor, SDGF-3, is identified as keratinocyte growth factor (KGF). Febs Letters. 328: 17-20. PMID 8344423 DOI: 10.1016/0014-5793(93)80956-U  0.309
1993 Rubin JS, Bottaro DP, Aaronson SA. Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product Bba - Reviews On Cancer. 1155: 357-371. PMID 8268192 DOI: 10.1016/0304-419X(93)90015-5  0.659
1993 May M, Aaronson SA, LaRochelle WJ. Platelet-derived growth factor AB heterodimer interchain interactions influence secretion as well as receptor binding and activation. Biochemistry. 32: 11734-40. PMID 8218243 DOI: 10.1021/Bi00094A033  0.313
1993 Panos RJ, Rubin JS, Aaronson SA, Mason RJ. Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast- conditioned medium Journal of Clinical Investigation. 92: 969-977. PMID 7688769 DOI: 10.1172/Jci116673  0.329
1993 Ishibashi T, Bottaro DP, Chan A, Miki T, Aaronson SA. Expression cloning of a human dual-specificity phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 89: 12170-4. PMID 1281549 DOI: 10.1073/Pnas.89.24.12170  0.701
1992 Molloy CJ, Fleming TP, Bottaro DP, Cuadrado A, Aaronson SA. Platelet-derived growth factor stimulation of GTPase-activating protein tyrosine phosphorylation in control and c-H-ras-expressing NIH 3T3 cells correlates with p21ras activation. Molecular and Cellular Biology. 12: 3903-9. PMID 1508192 DOI: 10.1128/Mcb.12.9.3903  0.697
1992 Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA. Emergence of the keratinocyte growth factor multigene family during the great ape radiation. Proceedings of the National Academy of Sciences of the United States of America. 89: 9287-91. PMID 1409637 DOI: 10.1073/Pnas.89.19.9287  0.324
1992 Rong S, Bodescot M, Blair D, Dunn J, Nakamura T, Mizuno K, Park M, Chan A, Aaronson S, Vande Woude GF. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Molecular and Cellular Biology. 12: 5152-8. PMID 1406687 DOI: 10.1128/Mcb.12.11.5152  0.409
1992 Fleming TP, Matsui T, Aaronson SA. Platelet-derived growth factor (PDGF) receptor activation in cell transformation and human malignancy Experimental Gerontology. 27: 523-532. PMID 1385192 DOI: 10.1016/0531-5565(92)90007-M  0.389
1992 Miki T, Bottaro DP, Fleming TP, Smith CL, Burgess WH, Chan AM, Aaronson SA. Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proceedings of the National Academy of Sciences of the United States of America. 89: 246-50. PMID 1309608 DOI: 10.1073/Pnas.89.1.246  0.687
1991 LaRochelle WJ, May-Siroff M, Robbins KC, Aaronson SA. A novel mechanism regulating growth factor association with the cell surface: identification of a PDGF retention domain. Genes & Development. 5: 1191-9. PMID 2065974 DOI: 10.1101/Gad.5.7.1191  0.31
1991 Takahashi R, Hashimoto T, Xu HJ, Hu SX, Matsui T, Miki T, Bigo-Marshall H, Aaronson SA, Benedict WF. The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 5257-61. PMID 2052605 DOI: 10.1073/Pnas.88.12.5257  0.372
1991 Miki T, Fleming TP, Crescenzi M, Molloy CJ, Blam SB, Reynolds SH, Aaronson SA. Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proceedings of the National Academy of Sciences of the United States of America. 88: 5167-71. PMID 2052597 DOI: 10.1073/Pnas.88.12.5167  0.351
1991 Larochelle WJ, Giese N, May-Siroff M, Robbins KC, Aaronson SA. Chimeric molecules map and dissociate the potent transforming and secretory properties of PDGF A and PDGF B. Journal of Cell Science. Supplement. 13: 31-42. PMID 1964685 DOI: 10.1242/Jcs.1990.Supplement_13.5  0.308
1991 Hart MJ, Eva A, Evans T, Aaronson SA, Cerione RA. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product Nature. 354: 311-314. PMID 1956381 DOI: 10.1038/354311A0  0.338
1991 Bottaro DP, Rubin JS, Faletto DL, Chan AM, Kmiecik TE, Vande Woude GF, Aaronson SA. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (New York, N.Y.). 251: 802-4. PMID 1846706 DOI: 10.1126/Science.1846706  0.687
1991 Miki T, Fleming TP, Bottaro DP, Rubin JS, Ron D, Aaronson SA. Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop Science. 251: 72-75. PMID 1846048 DOI: 10.1126/Science.1846048  0.698
1991 Chan AM, Rubin JS, Bottaro DP, Hirschfield DW, Chedid M, Aaronson SA. Identification of a competitive HGF antagonist encoded by an alternative transcript. Science (New York, N.Y.). 254: 1382-5. PMID 1720571 DOI: 10.1126/Science.1720571  0.689
1991 Heidaran MA, Pierce JH, Lombardi D, Ruggiero M, Gutkind JS, Matsui T, Aaronson SA. Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways. Molecular and Cellular Biology. 11: 134-42. PMID 1702511 DOI: 10.1128/Mcb.11.1.134  0.304
1991 Di Fiore PP, Segatto O, Aaronson SA. Cloning, expression, and biological effects of erbB-2/neu gene in mammalian cells. Methods in Enzymology. 198: 272-7. PMID 1677443 DOI: 10.1016/0076-6879(91)98028-5  0.347
1991 AARONSON SA, BOTTARO DP, MIKI T, RON D, FINCH PW, FLEMING TP, AHN J, TAYLOR WG, RUBIN JS. Keratinocyte Growth Factor: A Fibroblast Growth Factor Family Member with Unusual Target Cell Specificity Annals of the New York Academy of Sciences. 638: 62-77. PMID 1664700 DOI: 10.1111/J.1749-6632.1991.Tb49018.X  0.665
1991 Aaronson SA. Growth factors and cancer Science. 254: 1146-1153. PMID 1659742 DOI: 10.1126/Science.1659742  0.333
1991 Smith EA, Seldin MF, Martinez L, Watson ML, Choudhury GG, Lalley PA, Pierce J, Aaronson S, Barker J, Naylor SL. Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5. Proceedings of the National Academy of Sciences of the United States of America. 88: 4811-5. PMID 1647018 DOI: 10.1073/Pnas.88.11.4811  0.304
1991 Yu JC, Heidaran MA, Pierce JH, Gutkind JS, Lombardi D, Ruggiero M, Aaronson SA. Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction. Molecular and Cellular Biology. 11: 3780-5. PMID 1646396 DOI: 10.1128/Mcb.11.7.3780  0.313
1990 Kraus MH, Di Fiore PP, Pierce JH, Aaronson SA. Different mechanisms are responsible for oncogene activation in human mammary neoplasia. Cancer Treatment and Research. 40: 49-66. PMID 2908661 DOI: 10.1007/978-1-4613-1733-3_3  0.358
1990 Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA. Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proceedings of the National Academy of Sciences of the United States of America. 86: 9193-7. PMID 2687875 DOI: 10.1073/Pnas.86.23.9193  0.382
1990 Aaronson SA, Rubin JS, Finch PW, Wong J, Marchese C, Falco J, Taylor WG, Kraus MH. Growth factor-regulated pathways in epithelial cell proliferation American Review of Respiratory Disease. 142. PMID 2252277 DOI: 10.1164/Ajrccm/142.6_Pt_2.S7  0.406
1990 Crescenzi M, Fleming TP, Lassar AB, Weintraub H, Aaronson SA. MyoD induces growth arrest independent of differentiation in normal and transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 8442-6. PMID 2236052 DOI: 10.1073/Pnas.87.21.8442  0.365
1990 Kruh GD, Perego R, Miki T, Aaronson SA. The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases. Proceedings of the National Academy of Sciences of the United States of America. 87: 5802-6. PMID 2198571 DOI: 10.1073/Pnas.87.15.5802  0.329
1990 Di Fiore PP, Segatto O, Lonardo F, Fazioli F, Pierce JH, Aaronson SA. The carboxy-terminal domains of erbB-2 and epidermal growth factor receptor exert different regulatory effects on intrinsic receptor tyrosine kinase function and transforming activity. Molecular and Cellular Biology. 10: 2749-56. PMID 2188097 DOI: 10.1128/Mcb.10.6.2749  0.34
1990 Di Fiore PP, Segatto O, Taylor WG, Aaronson SA, Pierce JH. EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling. Science (New York, N.Y.). 248: 79-83. PMID 2181668 DOI: 10.1126/Science.2181668  0.362
1990 LaRochelle WJ, Giese N, May-Siroff M, Robbins KC, Aaronson SA. Molecular localization of the transforming and secretory properties of PDGF A and PDGF B. Science (New York, N.Y.). 248: 1541-4. PMID 2163109 DOI: 10.1126/Science.2163109  0.311
1990 Giese N, LaRochelle WJ, May-Siroff M, Robbins KC, Aaronson SA. A small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity. Molecular and Cellular Biology. 10: 5496-501. PMID 1697931 DOI: 10.1128/Mcb.10.10.5496  0.328
1990 Marchese C, Rubin J, Ron D, Faggioni A, Torrisi MR, Messina A, Frati L, Aaronson SA. Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: differentiation response distinguishes KGF from EGF family. Journal of Cellular Physiology. 144: 326-32. PMID 1696274 DOI: 10.1002/Jcp.1041440219  0.362
1989 Rubin JS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA. Purification and characterization of a newly identified growth factor specific for epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 86: 802-806. PMID 2915979 DOI: 10.1073/Pnas.86.3.802  0.394
1989 Segatto O, King CR, Pierce JH, Di Fiore PP, Aaronson SA. Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene. Molecular and Cellular Biology. 8: 5570-4. PMID 2907606 DOI: 10.1128/Mcb.8.12.5570  0.349
1989 Fleming TP, Matsui T, Molloy CJ, Robbins KC, Aaronson SA. Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors Proceedings of the National Academy of Sciences of the United States of America. 86: 8063-8067. PMID 2813378 DOI: 10.1073/Pnas.86.20.8063  0.361
1989 Aaronson SA, Falco JP, Taylor WG, Cech AC, Marchese C, Finch PW, Rubin J, Weissman BE, Di Fiore PP. Pathways in which growth factors and oncogenes interact in epithelial cell mitogenic signal transduction. Annals of the New York Academy of Sciences. 567: 122-9. PMID 2802446 DOI: 10.1111/J.1749-6632.1989.Tb16464.X  0.32
1989 Pech M, Rao CD, Robbins KC, Aaronson SA. Functional identification of regulatory elements within the promoter region of platelet-derived growth factor 2. Molecular and Cellular Biology. 9: 396-405. PMID 2651898 DOI: 10.1128/Mcb.9.2.396  0.388
1989 Pech M, Gazit A, Arnstein P, Aaronson SA. Generation of fibrosarcomas in vivo by a retrovirus that expresses the normal B chain of platelet-derived growth factor and mimics the alternative splice pattern of the v-sis oncogene. Proceedings of the National Academy of Sciences of the United States of America. 86: 2693-7. PMID 2649890 DOI: 10.1073/Pnas.86.8.2693  0.372
1989 Matsui T, Pierce JH, Fleming TP, Greenberger JS, LaRochelle WJ, Ruggiero M, Aaronson SA. Independent expression of human α or β platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic ahd chemotactic signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 86: 8314-8318. PMID 2554309 DOI: 10.1073/Pnas.86.21.8314  0.334
1989 Matsui T, Heidaran M, Miki T, Popescu N, Rochelle WL, Kraus M, Pierce J, Aaronson S. Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science. 243: 800-804. PMID 2536956 DOI: 10.1126/Science.2536956  0.337
1989 Molloy CJ, Bottaro DP, Fleming TP, Marshall MS, Gibbs JB, Aaronson SA. PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature. 342: 711-4. PMID 2480526 DOI: 10.1038/342711A0  0.691
1989 LaRochelle WJ, Robbins KC, Aaronson SA. Immunochemical localization of the epitope for a monoclonal antibody that neutralizes human platelet-derived growth factor mitogenic activity. Molecular and Cellular Biology. 9: 3538-42. PMID 2477688 DOI: 10.1128/Mcb.9.8.3538  0.305
1989 Finch PW, Rubin JS, Miki T, Ron D, Aaronson SA. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth Science. 245: 752-755. PMID 2475908 DOI: 10.1126/Science.2475908  0.379
1989 Giese N, May-Siroff M, LaRochelle WJ, van Wyke Coelingh K, Aaronson SA. Expression and purification of biologically active v-sis/platelet-derived growth factor B protein by using a baculovirus vector system. Journal of Virology. 63: 3080-3086. DOI: 10.1128/Jvi.63.7.3080-3086.1989  0.366
1988 Eva A, Pierce JH, Aaronson SA. Interactions of retroviral and cellular transforming genes with hematopoietic cells. Annals of the New York Academy of Sciences. 511: 148-70. PMID 3326463 DOI: 10.1111/J.1749-6632.1987.Tb36245.X  0.399
1988 Kawakami T, Kawakami Y, Aaronson SA, Robbins KC. Acquisition of transforming properties by FYN, a normal SRC-related human gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 3870-4. PMID 3287380 DOI: 10.1073/Pnas.85.11.3870  0.384
1988 Eva A, Vecchio G, Rao CD, Tronick SR, Aaronson SA. The predicted DBL oncogene product defines a distinct class of transforming proteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 2061-5. PMID 3281159 DOI: 10.1073/Pnas.85.7.2061  0.367
1988 Rao CD, Pech M, Robbins KC, Aaronson SA. The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor. Molecular and Cellular Biology. 8: 284-92. PMID 3275870 DOI: 10.1128/Mcb.8.1.284  0.331
1988 Pierce JH, Ruggiero M, Fleming TP, Di Fiore PP, Greenberger JS, Varticovski L, Schlessinger J, Rovera G, Aaronson SA. Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells Science. 239: 628-631. PMID 3257584 DOI: 10.1126/Science.3257584  0.338
1988 Kraus MH, Pierce JH, Fleming TP, Robbins KC, Di Fiore PP, Aaronson SA. Mechanisms by which genes encoding growth factors and growth factor receptors contribute to malignant transformation Annals of the New York Academy of Sciences. 551: 320-336. PMID 3072902 DOI: 10.1111/J.1749-6632.1988.Tb22358.X  0.328
1988 Beckmann MP, Betsholtz C, Heldin CH, Westermark B, Di Marco E, Di Fiore PP, Robbins KC, Aaronson SA. Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains. Science (New York, N.Y.). 241: 1346-9. PMID 2842868 DOI: 10.1126/Science.2842868  0.343
1988 Moscat J, Molloy CJ, Fleming TP, Aaronson SA. Epidermal Growth Factor Activates Phosphoinositide Turnover and Protein Kinase C in BALB/MK Keratinocytes Molecular Endocrinology. 2: 799-805. PMID 2459606 DOI: 10.1210/Mend-2-9-799  0.356
1988 Di Fiore PP, Falco J, Borrello I, Weissman B, Aaronson SA. The calcium signal for BALB/MK keratinocyte terminal differentiation counteracts epidermal growth factor (EGF) very early in the EGF-induced proliferative pathway. Molecular and Cellular Biology. 8: 557-63. PMID 2451119 DOI: 10.1128/Mcb.8.2.557  0.362
1988 Di Fiore PP, Pierce JH, Kraus MH, Fleming TP, Robbins KC, Aaronson SA. The role of growth factors and growth factor receptors in neoplastic cell transformation Lung Cancer. 4: 135-154. DOI: 10.1016/S0169-5002(88)80037-0  0.328
1988 Ron D, Tronick SR, Aaronson SA, Eva A. Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells. The Embo Journal. 7: 2465-2473. DOI: 10.1002/J.1460-2075.1988.Tb03093.X  0.372
1987 Kruh GD, King CR, Kraus MH, Popescu NC, Amsbaugh SC, McBride WO, Aaronson SA. A novel human gene closely related to the abl proto-oncogene. Science (New York, N.Y.). 234: 1545-8. PMID 3787260 DOI: 10.1126/Science.3787260  0.358
1987 Lacal JC, Aaronson SA. Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide. Molecular and Cellular Biology. 6: 4214-20. PMID 3540608 DOI: 10.1128/Mcb.6.12.4214  0.329
1987 Di Fiore PP, Pierce JH, Fleming TP, Hazan R, Ullrich A, King CR, Schlessinger J, Aaronson SA. Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells Cell. 51: 1063-1070. PMID 3500791 DOI: 10.1016/0092-8674(87)90592-7  0.377
1987 Srivastava SK, Wheelock RH, Aaronson SA, Eva A. Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene. Proceedings of the National Academy of Sciences of the United States of America. 83: 8868-72. PMID 3491366 DOI: 10.1073/Pnas.83.23.8868  0.393
1987 Matyas GR, Aaronson SA, Brady RO, Fishman PH. Alteration of glycolipids in ras-transfected NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 6065-8. PMID 3476926 DOI: 10.1073/Pnas.84.17.6065  0.357
1987 Dahlberg JE, Mitsuya H, Blam SB, Broder S, Aaronson SA. Broad spectrum antiretroviral activity of 2',3'-dideoxynucleosides. Proceedings of the National Academy of Sciences of the United States of America. 84: 2469-73. PMID 3470806 DOI: 10.1073/Pnas.84.8.2469  0.332
1987 Pasti G, Lacal JC, Warren BS, Aaronson SA, Blumberg PM. Loss of mouse fibroblast cell response to phorbol esters restored by microinjected protein kinase C. Nature. 324: 375-7. PMID 3466038 DOI: 10.1038/324375A0  0.325
1987 Lacal JC, Fleming TP, Warren BS, Blumberg PM, Aaronson SA. Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product Molecular and Cellular Biology. 7: 4146-4149. PMID 3323889 DOI: 10.1128/Mcb.7.11.4146  0.32
1987 Lacal JC, Moscat J, Aaronson SA. Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene. Nature. 330: 269-72. PMID 3313065 DOI: 10.1038/330269A0  0.377
1987 Hagag N, Lacal JC, Graber M, Aaronson S, Viola MV. Microinjection of ras p21 induces a rapid rise in intracellular pH. Molecular and Cellular Biology. 7: 1984-1988. PMID 3037340 DOI: 10.1128/Mcb.7.5.1984  0.315
1987 Kawakami T, Sherman L, Dahlberg J, Gazit A, Yaniv A, Tronick SR, Aaronson SA. Nucleotide sequence analysis of equine infectious anemia virus proviral DNA. Virology. 158: 300-12. PMID 3035786 DOI: 10.1016/0042-6822(87)90202-9  0.305
1987 Giese NA, Robbins KC, Aaronson SA. The role of individual cysteine residues in the structure and function of the v-sis gene product. Science (New York, N.Y.). 236: 1315-8. PMID 3035718 DOI: 10.1126/Science.3035718  0.319
1987 Finzi E, Fleming T, Segatto O, Pennington CY, Bringman TS, Derynck R, Aaronson SA. The human transforming growth factor type alpha coding sequence is not a direct-acting oncogene when overexpressed in NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 3733-7. PMID 3035551 DOI: 10.1073/Pnas.84.11.3733  0.344
1987 Di Fiore PP, Pierce JH, Kraus MH, Segatto O, King CR, Aaronson SA. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science (New York, N.Y.). 237: 178-82. PMID 2885917 DOI: 10.1126/Science.2885917  0.439
1987 Pierce JH, Gazit A, Di Fiore PP, Kraus M, Pennington CY, Holmes KL, Davidson WF, Morse HC, Aaronson SA. Mammalian cell transformation by a recombinant murine retrovirus containing the avian erythroblastosis virus erbB gene. Current Topics in Microbiology and Immunology. 132: 55-61. PMID 2878795 DOI: 10.1007/978-3-642-71562-4_8  0.414
1987 Lacal JC, de la Peña P, Moscat J, Garcia-Barreno P, Anderson PS, Aaronson SA. Rapid stimulation of diacylglycerol production in Xenopus oocytes by microinjection of H-ras p21. Science (New York, N.Y.). 238: 533-6. PMID 2821623 DOI: 10.1126/Science.2821623  0.335
1987 Lacal JC, Aaronson SA. Monoclonal antibody Y13-259 recognizes an epitope of the p21 ras molecule not directly involved in the GTP-binding activity of the protein. Molecular and Cellular Biology. 6: 1002-9. PMID 2431273 DOI: 10.1128/Mcb.6.4.1002  0.34
1986 Yaniv A, Dahlberg J, Gazit A, Sherman L, Chiu IM, Tronick SR, Aaronson SA. Molecular cloning and physical characterization of integrated equine infectious anemia virus: molecular and immunologic evidence of its close relationship to ovine and caprine lentiviruses. Virology. 154: 1-8. PMID 3750842 DOI: 10.1016/0042-6822(86)90424-1  0.31
1986 Reynolds SH, Stowers SJ, Maronpot RR, Anderson MW, Aaronson SA. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse. Proceedings of the National Academy of Sciences of the United States of America. 83: 33-7. PMID 3510430 DOI: 10.1073/Pnas.83.1.33  0.317
1986 Lacal JC, Srivastava SK, Anderson PS, Aaronson SA. Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells. Cell. 44: 609-17. PMID 3004741 DOI: 10.1016/0092-8674(86)90270-9  0.346
1986 King CR, Kraus MH, Williams LT, Merlino GT, Pastan IH, Aaronson SA. Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs. Nucleic Acids Research. 13: 8477-86. PMID 3001641 DOI: 10.1093/Nar/13.23.8477  0.362
1986 Lacal JC, Aaronson SA. ras p21 deletion mutants and monoclonal antibodies as tools for localization of regions relevant to p21 function Proceedings of the National Academy of Sciences of the United States of America. 83: 5400-5404. PMID 2426696 DOI: 10.1073/Pnas.83.15.5400  0.325
1986 Rhim JS, Fujita J, Arnstein P, Aaronson SA. Neoplastic conversion of human keratinocytes by adenovirus 12-SV40 virus and chemical carcinogens Science. 232: 385-388. PMID 2421406 DOI: 10.1126/Science.2421406  0.342
1986 Yuasa Y, Reddy EP, Rhim JS, Tronick SR, Aaronson SA. ACTIVATED N-ras IN A HUMAN RECTAL CARCINOMA CELL LINE ASSOCIATED WITH CLONAL HOMOZYGOSITY IN myb LOCUS-RESTRICTION FRAGMENT POLYMORPHISM Japanese Journal of Cancer Research. 77: 639-647. DOI: 10.20772/Cancersci1985.77.7_639  0.35
1986 Needleman S, Kraus M, Srivastava S, Levine P, Aaronson S. High frequency of N-ras activation in acute myelogenous leukemia Blood. 67: 753-757. DOI: 10.1182/Blood.V67.3.753.Bloodjournal673753  0.313
1986 Gazit A, Pierce JH, Kraus MH, Di Fiore PP, Pennington CY, Aaronson SA. Mammalian cell transformation by a murine retrovirus vector containing the avian erythroblastosis virus erbB gene. Journal of Virology. 60: 19-28. DOI: 10.1128/Jvi.60.1.19-28.1986  0.416
1986 Lacal J, Anderson P, Aaronson S. Deletion mutants of Harvey ras p21 protein reveal the absolute requirement of at least two distant regions for GTP-binding and transforming activities. The Embo Journal. 5: 679-687. DOI: 10.1002/J.1460-2075.1986.Tb04267.X  0.357
1985 Srivastava SK, Yuasa Y, Reynolds SH, Aaronson SA. Effects of two major activating lesions on the structure and conformation of human ras oncogene products. Proceedings of the National Academy of Sciences of the United States of America. 82: 38-42. PMID 3918304 DOI: 10.1073/Pnas.82.1.38  0.347
1985 Srivastava SK, Lacal JC, Reynolds SH, Aaronson SA. Antibody of predetermined specificity to a carboxy-terminal region of H-ras gene products inhibits their guanine nucleotide-binding function. Molecular and Cellular Biology. 5: 3316-9. PMID 3915772 DOI: 10.1128/Mcb.5.11.3316  0.338
1985 Eva A, Aaronson SA. Isolation of a new human oncogene from a diffuse B-cell lymphoma Nature. 316: 273-275. PMID 3875039 DOI: 10.1038/316273A0  0.353
1985 Aaronson SA, Tronick SR. Transforming genes of human malignancies Carcinogenesis; a Comprehensive Survey. 10: 35-49. PMID 2998614 DOI: 10.1007/978-94-009-5466-3_6  0.379
1985 Leal F, Williams LT, Robbins KC, Aaronson SA. Evidence that the v-sis gene product transforms by interaction with the receptor for platelet-derived growth factor. Science (New York, N.Y.). 230: 327-30. PMID 2996133 DOI: 10.1126/Science.2996133  0.397
1985 Chiu IM, Yaniv A, Dahlberg JE, Gazit A, Skuntz SF, Tronick SR, Aaronson SA. Nucleotide sequence evidence for relationship of AIDS retrovirus to lentiviruses. Nature. 317: 366-8. PMID 2995822 DOI: 10.1038/317366A0  0.331
1985 Yaniv A, Dahlberg JE, Tronick SR, Chiu IM, Aaronson SA. Molecular cloning of integrated caprine arthritis-encephalitis virus. Virology. 145: 340-5. PMID 2992157 DOI: 10.1016/0042-6822(85)90169-2  0.341
1985 King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science (New York, N.Y.). 229: 974-6. PMID 2992089 DOI: 10.1126/Science.2992089  0.353
1985 King CR, Giese NA, Robbins KC, Aaronson SA. In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product. Proceedings of the National Academy of Sciences of the United States of America. 82: 5295-9. PMID 2991916 DOI: 10.1073/Pnas.82.16.5295  0.361
1985 Fujita J, Srivastava SK, Kraus MH, Rhim JS, Tronick SR, Aaronson SA. Frequency of molecular alterations affecting ras protooncogenes in human urinary tract tumors. Proceedings of the National Academy of Sciences of the United States of America. 82: 3849-53. PMID 2987950 DOI: 10.1073/Pnas.82.11.3849  0.313
1985 Pierce JH, Aaronson SA. Myeloid cell transformation by ras-containing murine sarcoma viruses Molecular and Cellular Biology. 5: 667-674. PMID 2985965 DOI: 10.1128/Mcb.5.4.667  0.398
1985 Reddy EP, Lipman D, Andersen PR, Tronick SR, Aaronson SA. Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene Journal of Virology. 53: 984-987. PMID 2983103 DOI: 10.1128/Jvi.53.3.984-987.1985  0.384
1985 Rhim JS, Jay G, Arnstein P, Price FM, Sanford KK, Aaronson SA. Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma viruses. Science (New York, N.Y.). 227: 1250-2. PMID 2579430 DOI: 10.1126/Science.2579430  0.379
1985 Weissman B, Aaronson SA. Members of the src and ras oncogene families supplant the epidermal growth factor requirement of BALB/MK-2 keratinocytes and induce distinct alterations in their terminal differentiation program Molecular and Cellular Biology. 5: 3386-3396. PMID 2427928 DOI: 10.1128/Mcb.5.12.3386  0.374
1985 Callahan R, Chiu IM, Wong JF, Tronick SR, Roe BA, Aaronson SA, Schlom J. A new class of endogenous human retroviral genomes. Science (New York, N.Y.). 228: 1208-11. PMID 2408338 DOI: 10.1126/Science.2408338  0.352
1985 Robbins K, Leal F, Pierce J, Aaronson S. The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein. The Embo Journal. 4: 1783-1792. DOI: 10.1002/J.1460-2075.1985.Tb03851.X  0.376
1984 Yuasa Y, Gol RA, Chang A, Chiu IM, Reddy EP, Tronick SR, Aaronson SA. Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 3670-4. PMID 6587382 DOI: 10.1073/Pnas.81.12.3670  0.31
1984 Balachandran R, Reddy EP, Dunn CY, Aaronson SA, Swan DC. Immunoglobulin synthesis and gene rearrangements in lymphoid cells transformed by replication-competent Rauscher murine leukemia virus: transformation of B cells at various stages of differentiation Embo Journal. 3: 3199-3207. PMID 6335428 DOI: 10.1002/J.1460-2075.1984.Tb02279.X  0.374
1984 Fujita J, Yoshida O, Yuasa Y, Rhim JS, Hatanaka M, Aaronson SA. Ha-ras oncogenes are activated by somatic alterations in human urinary tract tumours. Nature. 309: 464-6. PMID 6328318 DOI: 10.1038/309464A0  0.324
1984 Chiu IM, Reddy EP, Givol D, Robbins KC, Tronick SR, Aaronson SA. Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor. Cell. 37: 123-9. PMID 6327048 DOI: 10.1016/0092-8674(84)90307-6  0.325
1984 Pierce JH, Aaronson SA, Anderson SM. Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 81: 2374-8. PMID 6326123 DOI: 10.1073/Pnas.81.8.2374  0.415
1984 Srinivasan A, Reddy EP, Dunn CY, Aaronson SA. Molecular dissection of transcriptional control elements within the long terminal repeat of the retrovirus. Science (New York, N.Y.). 223: 286-9. PMID 6322296 DOI: 10.1126/Science.6322296  0.329
1984 Devare SG, Shatzman A, Robbins KC, Rosenberg M, Aaronson SA. Expression of the PDGF-related transforming protein of simian sarcoma virus in E. coli. Cell. 36: 43-9. PMID 6319011 DOI: 10.1016/0092-8674(84)90072-2  0.392
1984 Chiu IM, Callahan R, Tronick SR, Schlom J, Aaronson SA. Major pol gene progenitors in the evolution of oncoviruses. Science (New York, N.Y.). 223: 364-70. PMID 6197754 DOI: 10.1126/Science.6197754  0.32
1984 Gazit A, Igarashi H, Chiu IM, Srinivasan A, Yaniv A, Tronick SR, Robbins KC, Aaronson SA. Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation. Cell. 39: 89-97. PMID 6091919 DOI: 10.1016/0092-8674(84)90194-6  0.352
1984 Pierce JH, Aaronson SA. Interaction of acute transforming retroviruses with murine hematopoietic cells. Current Topics in Microbiology and Immunology. 113: 258-64. PMID 6090065 DOI: 10.1007/978-3-642-69860-6_44  0.348
1984 Narayanan R, Srinivasan A, Aaronson SA. Sequences in the long terminal repeats of the Moloney murine sarcoma virus-124 genome which control transforming gene function. Virology. 137: 32-40. PMID 6089418 DOI: 10.1016/0042-6822(84)90005-9  0.339
1984 Kraus MH, Yuasa Y, Aaronson SA. A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient. Proceedings of the National Academy of Sciences of the United States of America. 81: 5384-8. PMID 6089200 DOI: 10.1073/Pnas.81.17.5384  0.34
1983 Yuasa Y, Srivastava SK, Dunn CY, Rhim JS, Reddy EP, Aaronson SA. Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature. 303: 775-9. PMID 6866079 DOI: 10.1038/303775A0  0.328
1983 Needleman SW, Yuasa Y, Srivastava S, Aaronson SA. Normal cells of patients with high cancer risk syndromes lack transforming activity in the NIH/3T3 transfection assay. Science (New York, N.Y.). 222: 173-5. PMID 6623066 DOI: 10.1126/Science.6623066  0.306
1983 Robbins KC, Antoniades HN, Devare SG, Hunkapiller MW, Aaronson SA. Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor. Nature. 305: 605-8. PMID 6312326 DOI: 10.1038/305605A0  0.37
1983 Eva A, Tronick SR, Gol RA, Pierce JH, Aaronson SA. Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proceedings of the National Academy of Sciences of the United States of America. 80: 4926-30. PMID 6308661 DOI: 10.1073/Pnas.80.16.4926  0.386
1983 Doolittle RF, Hunkapiller MW, Hood LE, Devare SG, Robbins KC, Aaronson SA, Antoniades HN. Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor Science. 221: 275-277. PMID 6304883 DOI: 10.1126/Science.6304883  0.389
1983 Eva A, Aaronson SA. Frequent activation of c-kis as a transforming gene in fibrosarcomas induced by methylcholanthrene Science. 220: 955-956. PMID 6302839 DOI: 10.1126/Science.6302839  0.359
1983 Devare SG, Reddy EP, Law JD, Robbins KC, Aaronson SA. Nucleotide sequence of the simian sarcoma virus genome: Demonstration that its acquired cellular sequences encode the transforming gene product p28(sis) Proceedings of the National Academy of Sciences of the United States of America. 80: 731-735. PMID 6298772 DOI: 10.1073/Pnas.80.3.731  0.361
1983 Weissman BE, Aaronson SA. BALB and kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent BALB/c mouse epidermal keratinocyte lines Cell. 32: 599-606. PMID 6297803 DOI: 10.1016/0092-8674(83)90479-8  0.393
1983 Merregaert J, Aaronson SA. Characterization of inducible type-C RNA viruses of mouse strains from different geographic areas. Virology. 123: 165-74. PMID 6183824 DOI: 10.1016/0042-6822(82)90303-8  0.352
1983 Naharro G, Tronick SR, Rasheed S, Gardner MB, Aaronson SA, Robbins KC. Molecular cloning of integrated Gardner-Rasheed feline sarcoma virus: genetic structure of its cell-derived sequence differs from that of other tyrosine kinase-coding onc genes. Journal of Virology. 47: 611-619. DOI: 10.1128/Jvi.47.3.611-619.1983  0.402
1983 Chiu IM, Andersen PR, Aaronson SA, Tronick SR. Molecular cloning of the unintegrated squirrel monkey retrovirus genome: organization and distribution of related sequences in primate DNAs. Journal of Virology. 47: 434-441. DOI: 10.1128/Jvi.47.3.434-441.1983  0.302
1983 Pierce JH, Aaronson SA. In vitro transformation of murine pre-B lymphoid cells by Snyder-Theilen feline sarcoma virus. Journal of Virology. 46: 993-1002. DOI: 10.1128/Jvi.46.3.993-1002.1983  0.401
1982 McBride OW, Swan DC, Santos E, Barbacid M, Tronick SR, Aaronson SA. Localization of the normal allele of T24 human bladder carcinoma oncogene to chromosome 11. Nature. 300: 773-4. PMID 7177197 DOI: 10.1038/300773A0  0.363
1982 Pulciani S, Santos E, Lauver AV, Long LK, Aaronson SA, Barbacid M. Oncogenes in solid human tumours. Nature. 300: 539-42. PMID 7144906 DOI: 10.1038/300539A0  0.326
1982 Westin EH, Gallo RC, Arya SK, Eva A, Souza LM, Baluda MA, Aaronson SA, Wong-Staal F. Differential expression of the amv gene in human hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2194-8. PMID 6954533 DOI: 10.1073/Pnas.79.7.2194  0.407
1982 Taub R, Kirsch I, Morton C, Lenoir G, Swan D, Tronick S, Aaronson S, Leder P. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 7837-41. PMID 6818551 DOI: 10.1073/Pnas.79.24.7837  0.339
1982 Robbins KC, Devare SG, Reddy EP, Aaronson SA. In vivo identification of the transforming gene product of simian sarcoma virus Science. 218: 1131-1133. PMID 6293053 DOI: 10.1126/Science.6293053  0.377
1982 Habara A, Reddy EP, Aaronson SA. Rauscher murine leukemia virus: Molecular cloning of infectious integrated proviral DNA Journal of Virology. 44: 731-735. PMID 6292529 DOI: 10.1128/Jvi.44.2.731-735.1982  0.389
1982 Srinivasan A, Dunn CY, Yuasa Y, Devare SG, Reddy EP, Aaronson SA. Abelson murine leukemia virus: Structural requirements for transforming gene function Proceedings of the National Academy of Sciences of the United States of America. 79: 5508-5512. PMID 6291048 DOI: 10.1073/Pnas.79.18.5508  0.397
1982 Prakash K, McBride OW, Swan DC, Devare SG, Tronick SR, Aaronson SA. Molecular cloning and chromosomal mapping of a human locus related to the transforming gene of Moloney murine sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 5210-4. PMID 6291031 DOI: 10.1073/Pnas.79.17.5210  0.325
1982 Swan DC, McBride OW, Robbins KC, Keithley DA, Reddy EP, Aaronson SA. Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4691-5. PMID 6289313 DOI: 10.1073/Pnas.79.15.4691  0.322
1982 Pierce JH, Aaronson SA. BALB- and Harvey-murine sarcoma virus transformation of a novel lymphoid progenitor cell. The Journal of Experimental Medicine. 156: 873-87. PMID 6286838 DOI: 10.1084/Jem.156.3.873  0.395
1982 Devare SG, Reddy EP, Robbins KC, Andersen PR, Tronick SR, Aaronson SA. Nucleotide sequence of the transforming gene of simian sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 3179-82. PMID 6285340 DOI: 10.1073/Pnas.79.10.3179  0.328
1982 Devare SG, Reddy EP, Law JD, Aaronson SA. Nucleotide sequence analysis of the long terminal repeat of integrated simian sarcoma virus: Evolutionary relationship with other mammalian retroviral long terminal repeats Journal of Virology. 42: 1108-1113. PMID 6284990 DOI: 10.1128/Jvi.42.3.1108-1113.1982  0.322
1982 Westin EH, Wong-Staal F, Gelmann EP, Dalla-Favera R, Papas TS, Lautenberger JA, Eva A, Reddy EP, Tronick SR, Aaronson SA, Gallo RC. Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2490-4. PMID 6283530 DOI: 10.1073/Pnas.79.8.2490  0.382
1982 Santos E, Tronick SR, Aaronson SA, Pulciani S, Barbacid M. T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes. Nature. 298: 343-7. PMID 6283384 DOI: 10.1038/298343A0  0.363
1982 Rasheed S, Barbacid M, Aaronson S, Gardner MB. Origin and biological properties of a new feline sarcoma virus. Virology. 117: 238-44. PMID 6175084 DOI: 10.1016/0042-6822(82)90522-0  0.372
1982 Eva A, Robbins KC, Andersen PR, Srinivasan A, Tronick SR, Reddy EP, Ellmore NW, Galen AT, Lautenberger JA, Papas TS, Westin EH, Wong-Staal F, Gallo RC, Aaronson SA. Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature. 295: 116-9. PMID 6173755 DOI: 10.1038/295116A0  0.382
1981 Andersen PR, Devare SG, Tronick SR, Ellis RW, Aaronson SA, Scolnick EM. Generation of BALB-MuSV and Ha-MuSV by type C virus transduction of homologous transforming genes from different species Cell. 26: 129-134. PMID 6276008 DOI: 10.1016/0092-8674(81)90041-6  0.387
1981 Aaronson SA, Barbacid M, Dunn CY, Reddy EP. Genetic approaches toward elucidating the mechanisms of type-C virus-induced leukemia. Haematology and Blood Transfusion. 26: 455-9. PMID 6274759 DOI: 10.1007/978-3-642-67984-1_83  0.388
1981 Merregaert J, Barbacid M, Aaronson SA. Recombinants between temperature-sensitive mutants of rauscher murine leukemia virus and BALB:virus-2: genetic mapping of the Rauscher murine leukemia virus genome. Journal of Virology. 39: 219-28. PMID 6268812 DOI: 10.1128/Jvi.39.1.219-228.1981  0.367
1981 Robbins KC, Devare SG, Aaronson SA. Molecular cloning of integrated simian sarcoma virus: genome organization of infectious DNA clones. Proceedings of the National Academy of Sciences of the United States of America. 78: 2918-22. PMID 6265924 DOI: 10.1073/Pnas.78.5.2918  0.383
1981 Srinivasan A, Reddy EP, Aaronson SA. Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA. Proceedings of the National Academy of Sciences of the United States of America. 78: 2077-81. PMID 6264461 DOI: 10.1073/Pnas.78.4.2077  0.377
1981 Reddy EP, Smith MJ, Canaani E, Robbins KC, Tronick SR, Zain S, Aaronson SA. Nucleotide sequence analysis of the transforming region and large terminal redundancies of Moloney murine sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 77: 5234-8. PMID 6254069 DOI: 10.1073/Pnas.77.9.5234  0.328
1981 Canaani E, Tronick SR, Robbins KC, Andersen PR, Dunn CY, Aaronson SA. Cellular origin of the transforming gene of Moloney murine sarcoma virus. Cold Spring Harbor Symposia On Quantitative Biology. 727-34. PMID 6253207 DOI: 10.1101/Sqb.1980.044.01.078  0.357
1981 Reddy EP, Smith MJ, Aaronson SA. Complete nucleotide sequence and organization of the Moloney murine sarcoma virus genome Science. 214: 445-450. PMID 6170110 DOI: 10.1126/Science.6170110  0.353
1981 Oroszlan S, Barbacid M, Copeland TD, Aaronson SA, Gilden RV. Chemical and Immunological characterization of the major structural protein (p28) of MMC-1, a rhesus monkey endogenous type C virus: homology with the major structural protein of avian reticuloendotheliosis virus. Journal of Virology. 39: 845-54. PMID 6169843 DOI: 10.1128/Jvi.39.3.845-854.1981  0.378
1981 Andersen PR, Tronick SR, Aaronson SA. Structural organization and biological activity of molecular clones of the integrated genome of a BALB/c mouse sarcoma virus. Journal of Virology. 40: 431-439. DOI: 10.1128/Jvi.40.2.431-439.1981  0.369
1980 Canaani E, Aaronson SA. Isolation and characterization of naturally occuring deletion mutants of Moloney murine sarcoma virus. Virology. 105: 456-66. PMID 7423856 DOI: 10.1016/0042-6822(80)90046-X  0.375
1980 Barbacid M, Bolognesi D, Aaronson SA. Humans have antibodies capable of recognizing oncoviral glycoproteins: demonstration that these antibodies are formed in response to cellular modification of glycoproteins rather than as consequence of exposure to virus. Proceedings of the National Academy of Sciences of the United States of America. 77: 1617-21. PMID 6154936 DOI: 10.1073/Pnas.77.3.1617  0.322
1980 Rosen SW, Weintraub BD, Aaronson SA. Nonrandom ectopic protein production by malignant cells: direct evidence in vitro. The Journal of Clinical Endocrinology and Metabolism. 50: 834-41. PMID 6154718 DOI: 10.1210/Jcem-50-5-834  0.301
1980 Barbacid M, Daniel MD, Aaronson SA. Immunological relationships of OMC-1, an endogenous virus of owl monkeys, with mammalian and avian type C viruses. Journal of Virology. 33: 561-6. PMID 6154152 DOI: 10.1128/Jvi.33.1.561-566.1980  0.34
1980 Dahlberg JE, Tronick SR, Aaronson SA. Immunological relationships of an endogenous guinea pig retrovirus with prototype mammalian type B and type D retroviruses. Journal of Virology. 33: 522-30. PMID 6154150 DOI: 10.1128/Jvi.33.1.522-530.1980  0.345
1980 Aaronson SA, Barbacid M. Viral genes involved in leukemogenesis. I. Generation of recombinants between oncogenic and nononcogenic mouse type-C viruses in tissue culture. The Journal of Experimental Medicine. 151: 467-80. PMID 6153214 DOI: 10.1084/Jem.151.2.467  0.401
1980 Canaani E, Robbins KC, Aaronson SA. The transforming gene of Moloney murine sarcoma virus. Nature. 282: 378-83. PMID 503218 DOI: 10.1038/282378A0  0.374
1980 Tronick SR, Robbins KC, Canaani E, Devare SG, Andersen PR, Aaronson SA. Molecular cloning of Moloney murine sarcoma virus: arrangement of virus-related sequences within the normal mouse genome. Proceedings of the National Academy of Sciences of the United States of America. 76: 6314-8. PMID 392518 DOI: 10.1073/Pnas.76.12.6314  0.355
1979 Robbins KC, Barbacid M, Porzig KJ, Aaronson SA. Involvement of different exogenous feline leukemia virus subgroups in the generation of independent feline sarcoma virus isolates. Virology. 97: 1-11. PMID 224571 DOI: 10.1016/0042-6822(79)90367-2  0.322
1979 Porzig KJ, Robbins KC, Aaronson SA. Cellular regulation of mammalian sarcoma virus expression: a gene regulation model for oncogenesis. Cell. 16: 875-84. PMID 222469 DOI: 10.1016/0092-8674(79)90102-8  0.404
1979 Canaani E, Aaronson SA. Restriction enzyme analysis of mouse cellular type C viral DNA: Emergence of new viral sequences in spontaneous AKR/J lymphomas Proceedings of the National Academy of Sciences of the United States of America. 76: 1677-1681. PMID 221902 DOI: 10.1073/Pnas.76.4.1677  0.343
1979 Andersen PR, Barbacid M, Tronick SR, Clark HF, Aaronson SA. Evolutionary relatedness of viper and primate endogenous retroviruses. Science (New York, N.Y.). 204: 318-21. PMID 219480 DOI: 10.1126/Science.219480  0.302
1979 Porzig KJ, Barbacid M, Aaronson SA. Biological properties and translational products of three independent isolates of feline sarcoma virus. Virology. 92: 91-107. PMID 217170 DOI: 10.1016/0042-6822(79)90217-4  0.397
1979 Barbacid M, Robbins KC, Aaronson SA. Wild mouse RNA tumor viruses. A nongenetically transmitted virus group closely related to exogenous leukemia viruses of laboratory mouse strains. The Journal of Experimental Medicine. 149: 254-66. PMID 216765 DOI: 10.1084/Jem.149.1.254  0.351
1979 Barbacid M, Hunter E, Aaronson SA. Avian reticuloendotheliosis viruses: evolutionary linkage with mammalian type C retroviruses. Journal of Virology. 30: 508-14. PMID 89204 DOI: 10.1128/Jvi.30.2.508-514.1979  0.333
1979 Krakower JM, Tronick SR, Gallagher RE, Gallo RC, Aaronson SA. Antigenic characterization of a new gibbon ape leukemia virus isolate: seroepidemiologic assessment of an outbreak of gibbon leukemia. International Journal of Cancer. 22: 715-20. PMID 82546 DOI: 10.1002/Ijc.2910220613  0.35
1979 Frankel AE, Gilbert JH, Porzig KJ, Scolnick EM, Aaronson SA. Nature and distribution of feline sarcoma virus nucleotide sequences. Journal of Virology. 30: 821-827. DOI: 10.1128/Jvi.30.3.821-827.1979  0.327
1978 Krakower JM, Aaronson SA. Seroepidemiologic assessment of feline leukaemia virus infection risk for man. Nature. 273: 463-464. PMID 207994 DOI: 10.1038/273463A0  0.312
1978 Barbacid M, Troxler DH, Scolnick EM, Aaronson SA. Analysis of translational products of Friend strain of spleen focus-forming virus. Journal of Virology. 27: 826-30. PMID 81315 DOI: 10.1128/Jvi.27.3.826-830.1978  0.383
1978 Aaronson SA, Barbacid M. Origin and biological properties of a new BALB/c mouse sarcoma virus. Journal of Virology. 27: 366-73. PMID 80461 DOI: 10.1128/Jvi.27.2.366-373.1978  0.393
1978 Aaronson SA, Krakower JM, Tronick SR, Stephenson JR. Immunologic approaches toward detection of type C viral expression in man. Arthritis and Rheumatism. 21: S27-45. PMID 78714 DOI: 10.1002/Art.1780210905  0.364
1978 Krakower JM, Aaronson SA. Radioimmunologic characterization of RD-114 reverse transcriptase: evolutionary relatedness of mammalian type C viral pol gene products. Virology. 86: 127-37. PMID 78564 DOI: 10.1016/0042-6822(78)90013-2  0.35
1978 Barbacid M, Robbins KC, Hino S, Aaronson SA. Genetic recombination between mouse type C RNA viruses: a mechanism for endogenous viral gene amplification in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 75: 923-7. PMID 76313 DOI: 10.1073/Pnas.75.2.923  0.404
1978 Hino S, Tronick SR, Heberling RL, Kalter SS, Hellman A, Aaronson SA. Endogenous New World primate retrovirus: interspecies antigenic determinants shared with the major structural protein of type-D RNA viruses of Old World monkeys. Proceedings of the National Academy of Sciences of the United States of America. 74: 5734-8. PMID 74833 DOI: 10.1073/Pnas.74.12.5734  0.361
1978 Barbacid M, Tronick SR, Aaronson SA. Isolation and characterization of an endogenous type C RNA virus of mink (Mv1Lu) cells. Journal of Virology. 25: 129-37. PMID 74420 DOI: 10.1128/Jvi.25.1.129-137.1978  0.405
1978 Lai MH, Verma IM, Tronick SR, Aaronson SA. Mammalian retrovirus-associated RNase H is virus coded. Journal of Virology. 27: 823-825. DOI: 10.1128/Jvi.27.3.823-825.1978  0.321
1978 Tronick SR, Cabradilla CD, Aaronson SA, Haseltine WA. 5'-terminal nucleotide sequences of mammalian type C helper viruses are conserved in the genomes of replication-defective mammalian transforming viruses. Journal of Virology. 26: 570-576. DOI: 10.1128/Jvi.26.3.570-576.1978  0.364
1978 Robbins KC, Okabe H, Tronick SR, Gilden RV, Aaronson SA. Molecular Mechanisms Involved in the Differential Expression of gag Gene Products by Clonal Isolates of a Primate Sarcoma Virus Journal of Virology. 25: 471-478. DOI: 10.1128/Jvi.25.2.471-478.1978  0.392
1977 Robbins KC, Stephenson JR, Cabradilla CD, Aaronson SA. Endogenous mouse type-C RNA virus of SWR cells: inducibility locus containing structural information for a new endogenous virus class. Virology. 82: 392-400. PMID 199995 DOI: 10.1016/0042-6822(77)90014-9  0.389
1977 Robbins KC, Cabradilla CD, Stephenson JR, Aaronson SA. Segregation of genetic information for a B-tropic leukemia virus with the structural locus for BALB:virus-1. Proceedings of the National Academy of Sciences of the United States of America. 74: 2953-7. PMID 197526 DOI: 10.1073/Pnas.74.7.2953  0.363
1977 Reynolds FH, Hanson CA, Aaronson SA, Stephenson JR. Type C viral gag gene expression in chicken embryo fibroblasts and avian sarcoma virus-transformed mammalian cells. Journal of Virology. 23: 74-9. PMID 196106 DOI: 10.1128/Jvi.23.1.74-79.1977  0.405
1977 Aaronson SA, Stephenson JR. Intracellular and systemic regulation of biologically distinguishable endogenous type C RNA viruses of mouse cells. Contemporary Topics in Immunobiology. 6: 107-26. PMID 194746 DOI: 10.1007/978-1-4684-3051-6_3  0.337
1977 Bensinger WI, Robbins KC, Greenberger JS, Aaronson SA. Different mechanisms for morphologic reversion of a clonal population of murine sarcoma virus-transformed nonproducer cells. Virology. 77: 750-61. PMID 193260 DOI: 10.1016/0042-6822(77)90496-2  0.398
1977 Peters RL, Sass B, Stephenson JR, Al-Ghazzouli IK, Hino S, Donahoe RM, Kende M, Aaronson SA, KElloff GJ. Immunoprevention of x-ray-induced leukemias in the C57BL mouse. Proceedings of the National Academy of Sciences of the United States of America. 74: 1697-701. PMID 193112 DOI: 10.1073/Pnas.74.4.1697  0.323
1977 Stephenson JR, Aaronson SA. Endogenous C-type viral expression in primates. Nature. 266: 469-72. PMID 193034 DOI: 10.1038/266469A0  0.369
1977 Stephenson JR, Essex M, Hino S, Hardy WD, Aaronson SA. Feline oncornavirus-associated cell-membrane antigen (FOCMA): distinction between FOCMA and the major virion glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. 74: 1219-23. PMID 191832 DOI: 10.1073/Pnas.74.3.1219  0.312
1977 Essex M, Cotter SM, Sliski AH, Hardy WD, Stephenson JR, Aaronson SA, Jarrett O. Horizontal transmission of feline leukemia virus under natural conditions in a feline leukemia cluster household. International Journal of Cancer. Journal International Du Cancer. 19: 90-6. PMID 188773 DOI: 10.1002/Ijc.2910190113  0.32
1977 Cabradilla CD, Robbins KC, Aaronson SA. Induction of mouse type-C virus by translational inhibitors: evidence for transcriptional derepression of a specific class of endogenous virus. Proceedings of the National Academy of Sciences of the United States of America. 73: 4541-5. PMID 188044 DOI: 10.1073/Pnas.73.12.4541  0.359
1977 Krakower JM, Barbacid M, Aaronson SA. Differential synthesis of mammalian type C viral gene products in infected cells. Journal of Virology. 24: 1-7. PMID 71358 DOI: 10.1128/Jvi.24.1.1-7.1977  0.404
1977 Tronick SR, Golub MM, Stephenson JR, Aaronson SA. Distribution and expression in mammals of genes ralated to an endogenous type C RNA virus of Odocoileus hemionus. Journal of Virology. 23: 1-9. PMID 69718 DOI: 10.1128/Jvi.23.1.1-9.1977  0.355
1977 Krakower JM, Barbacid M, Aaronson SA. Radioimmunoassay for mammalian type C viral reverse transcriptase. Journal of Virology. 22: 331-9. PMID 68126 DOI: 10.1128/Jvi.22.2.331-339.1977  0.354
1977 Barbacid M, Stephenson JR, Aaronson SA. Evolutionary relationships between gag gene-coded proteins of murine and primate endogenous type C RNA viruses. Cell. 10: 641-8. PMID 67898 DOI: 10.1016/0092-8674(77)90097-6  0.396
1977 Greenberger JS, Bensinger WI, Aaronson SA. Selective techniques for the isolation of morphological revertants of sarcoma virus-transformed cells. Methods in Cell Biology. 14: 237-49. PMID 63892 DOI: 10.1016/S0091-679X(08)60486-0  0.399
1977 Patni NJ, Dhawale SW, Aaronson S. Extracellular phosphatases of Chlamydomonas reinhardi and their regulation Journal of Bacteriology. 130: 205-211. PMID 15977 DOI: 10.1128/Jb.130.1.205-211.1977  0.309
1976 Gonda MA, Aaronson SA, Ellmore N, Zeve VH, Nagashima K. Ultrastructural studies of surface features of human normal and tumor cells in tissue culture by scanning and transmission electron microscopy. Journal of the National Cancer Institute. 56: 245-63. PMID 1255758 DOI: 10.1093/Jnci/56.2.245  0.3
1976 Kelloff GJ, Peters RL, Donahoe RM, Stephenson JR, Aaronson SA. Natural occurrence of tumors in mouse strains with different xenotropic and ecotropic endogenous viruses. Journal of the National Cancer Institute. 57: 85-9. PMID 187766 DOI: 10.1093/Jnci/57.1.85  0.324
1976 Stephenson JR, Peters RL, Hino S, Donahoe RM, Long LK, Aaronson SA, Kelloff GJ. Natural immunity in mice to structural polypeptides of endogenous type C RNA viruses. Journal of Virology. 19: 890-8. PMID 184303 DOI: 10.1128/Jvi.19.3.890-898.1976  0.347
1976 Stephenson JR, Hino S, Garrett EW, Aaronson SA. Immunological cross reactivity of Mason-Pfizer monkey virus with type C RNA viruses endogenous to primates. Nature. 261: 609-11. PMID 180419 DOI: 10.1038/261609A0  0.351
1976 Stephenson JR, Aaronson SA. Search for antigens and antibodies crossreactive with type C viruses of the woolly monkeys and gibbon ape in animal models and in humans. Proceedings of the National Academy of Sciences of the United States of America. 73: 1725-9. PMID 179097 DOI: 10.1073/Pnas.73.5.1725  0.336
1976 Smith EJ, Stephenson JR, Crittenden LB, Aaronson SA. Avian leukosis-sarcoma virus gene expression. Noncoordinate control of group-specific antigens in virus-negative avian cells. Virology. 70: 493-501. PMID 178098 DOI: 10.1016/0042-6822(76)90290-7  0.398
1976 Okabe H, Gilden RV, Hatanaka M, Stephenson JR, Gallagher RE, Aaronson SA, Gallo RC, Tronick SR. Immunological and biochemical characterisation of type C viruses isolated from cultured human AML cells. Nature. 260: 264-6. PMID 176595 DOI: 10.1038/260264A0  0.341
1976 Hampar B, Aaronson SA, Derge JG, Chakrabarty M, Showalter SD, Dunn CY. Activation of an endogenous mouse type C virus by ultraviolet-irradiated herpes simplex virus types 1 and 2. Proceedings of the National Academy of Sciences of the United States of America. 73: 646-50. PMID 174117 DOI: 10.1073/Pnas.73.2.646  0.354
1976 Aaronson SA, Tronick SR, Stephenson JR. Endogenous type C RNA virus of Odocoileus hemionus, a mammalian species of New World origin. Cell. 9: 489-94. PMID 62621 DOI: 10.1016/0092-8674(76)90094-5  0.332
1976 Aaronson SA, Stephenson JR. Endogenous type-C RNA viruses of mammalian cells. Biochimica Et Biophysica Acta. 458: 323-54. PMID 62589 DOI: 10.1016/0304-419X(76)90006-8  0.316
1976 Barbacid M, Stephenson JR, Aaronson SA. gag Gene of mammalian type-C RNA tumour viruses. Nature. 262: 554-9. PMID 60707 DOI: 10.1038/262554A0  0.362
1976 Hino S, Stephenson JR, Aaronson SA. Radiommunoassays for the 70,000-molecular-weight glycoproteins of endogenous mouse type C viruses: viral antigen expression in normal mouse tissues and sera. Journal of Virology. 18: 933-41. PMID 58081 DOI: 10.1128/Jvi.18.3.933-941.1976  0.362
1976 Stephenson JR, Aaronson SA. Induction of an endogenous B-tropic type C RNA virus from SWR/J mouse embryo cells in tissue culture. Virology. 70: 352-9. PMID 57668 DOI: 10.1016/0042-6822(76)90277-4  0.378
1976 Stephenson JR, Reynolds RK, Aaronson SA. Comparisons of the immunological properties of two structural polypeptides of type C RNA viruses endogenous to old world monkeys. Journal of Virology. 17: 374-84. PMID 56455 DOI: 10.1128/Jvi.17.2.374-384.1976  0.351
1976 Stephension JR, Reynolds RK, Tronick SR, Aaronson SA. Distribution of three classes of endogenous type-C RNA viruses among inbred strains of mice. Virology. 67: 404-14. PMID 52941 DOI: 10.1016/0042-6822(75)90442-0  0.356
1975 Greenberger JS, Stephenson JR, Aaronson SA. Temperature-sensitive mutants of murine leukemia virus. V. Impaired leukemogenic activity in vivo. International Journal of Cancer. Journal International Du Cancer. 15: 1009-15. PMID 1097342 DOI: 10.1002/Ijc.2910150618  0.35
1975 Stephenson JR, Cabradilla CD, Aaronson SA. Genetic factors influencing endogenous type-C RNA viruses of mouse cells: control of viral polypeptide expression in the C57BL/10 strain. Intervirology. 6: 258-69. PMID 186435 DOI: 10.1159/000149480  0.382
1975 Aaronson SA, Stephenson JR, Hino S, Tronick SR. Differential expression of helper viral structural polypeptides in cells transformed by clonal isolates of woolly monkey sarcoma virus. Journal of Virology. 16: 1117-23. PMID 171443 DOI: 10.1128/Jvi.16.5.1117-1123.1975  0.408
1975 Greenberger JS, Aaronson SA, Rosenthal DS, Moloney WC. Continuous production of peroxidase, esterase, alkaline phosphatase and lysozyme by clones of promyelocytes. Nature. 257: 143-144. PMID 169473 DOI: 10.1038/257143A0  0.321
1975 Aaronson SA, Stephenson JR. Differential cellular regulation of three distinct classes of type C RNA viruses endogenous to mouse cells. Cold Spring Harbor Symposia On Quantitative Biology. 39: 1129-37. PMID 169014 DOI: 10.1101/Sqb.1974.039.01.129  0.339
1975 Greenberger JS, Aaronson SA. Cycloheximide induction of xenotropic type C virus from synchronized mouse cells: metabolic requirements for virus activation Journal of Virology. 15: 64-70. PMID 163347 DOI: 10.1128/Jvi.15.1.64-70.1975  0.407
1975 Aaronson SA, Stephenson JR, Tronick SR, Hino S. Immunological analysis of structural polypeptides of woolly monkey-gibbon ape type C viruses. Expression of woolly monkey helper viral antigens in cells transformed by woolly monkey sarcoma virus. Bibliotheca Haematologica. 102-9. PMID 60994 DOI: 10.1159/000399106  0.365
1975 Tronick SR, Stephenson JR, Verma IM, Aaronson SA. Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions. Journal of Virology. 16: 1476-82. PMID 53294 DOI: 10.1128/Jvi.16.6.1476-1482.1975  0.337
1975 Dunn CY, Aaronson SA, Stephenson JR. Interactions of chemical inducers and steroid enhancers of endogenous mouse type-C RNA viruses. Virology. 66: 579-88. PMID 50667 DOI: 10.1016/0042-6822(75)90230-5  0.387
1975 Stephenson JR, Smith EJ, Crittenden LB, Aaronson SA. Analysis of antigenic determinants of structural polypeptides of avian type C tumor viruses. Journal of Virology. 16: 27-33. PMID 48560 DOI: 10.1128/Jvi.16.1.27-33.1975  0.317
1975 Tronick SR, Stephenson JR, Aaronson SA, Kawakami TG. Antigenic characterization of type C RNA virus isolates of gibbon apes. Journal of Virology. 15: 115-20. PMID 46280 DOI: 10.1128/Jvi.15.1.115-120.1975  0.361
1975 Stephenson JR, Tronick SR, Aaronson SA. Murine leukemia virus mutants with temperature-sensitive defects in precursor polypeptide cleavage Cell. 6: 543-550. DOI: 10.1016/0092-8674(75)90044-6  0.309
1974 Greenberger JS, Stephenson JR, Aoki T, Aaronson SA. Cell-surface antigens of murine sarcoma-virus-transformed non-producer cells: further evidence for lack of transplantation immunity. International Journal of Cancer. Journal International Du Cancer. 14: 145-52. PMID 4376511 DOI: 10.1002/Ijc.2910140202  0.338
1974 Stephenson JR, Anderson GR, Tronick SR, Aaronson SA. Evidence for genetic recombination between endogenous and exogenous mouse RNA type C viruses. Cell. 2: 87-94. PMID 4376054 DOI: 10.1016/0092-8674(74)90096-8  0.662
1974 Stephenson JR, Aaronson SA. Demonstration of a genetic factor influencing spontaneous release of a xenotropic virus of mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 4925-9. PMID 4373736 DOI: 10.1073/Pnas.71.12.4925  0.38
1974 Aaronson SA, Anderson GR, Dunn CY, Robbins KC. Induction of type C RNA virus by cycloheximide: increased expression of virus specific RNA Proceedings of the National Academy of Sciences of the United States of America. 71: 3941-3945. PMID 4372598 DOI: 10.1073/Pnas.71.10.3941  0.65
1974 Stephenson JR, Crow JD, Aaronson SA. Differential activation of biologically distinguishable endogenous mouse type C RNA viruses: interaction with host cell regulatory factors. Virology. 61: 411-9. PMID 4370962 DOI: 10.1016/0042-6822(74)90277-3  0.404
1974 Greenberger JS, Anderson GR, Aaronson SA. Transformation-Defective virus mutants in a class of morphologic revertants of sarcoma virus transformed nonproducer cells Cell. 2: 279-286. PMID 4370517 DOI: 10.1016/0092-8674(74)90022-1  0.666
1974 Stephenson JR, Aaronson SA, Arnstein P, Huebner RJ, Tronick SR. Demonstration of two immunologically distinct xenotropic type C RNA viruses of mouse cells. Virology. 61: 56-63. PMID 4369907 DOI: 10.1016/0042-6822(74)90241-4  0.397
1974 Aaronson SA, Stephenson JR. Widespread natural occurrence of high titers of neutralizing antibodies to a specific class of endogenous mouse type-C virus. Proceedings of the National Academy of Sciences of the United States of America. 71: 1957-61. PMID 4365577 DOI: 10.1073/Pnas.71.5.1957  0.376
1974 Aaronson SA, Stephenson JR, Greenberger JS. Cellular replication and the persistence of inducible RNA type C viruses. Journal of Virology. 13: 1404-7. PMID 4364905 DOI: 10.1128/Jvi.13.6.1404-1407.1974  0.406
1974 Stephenson JR, Aaronson SA. Temperature-sensitive mutants of murine leukemia virus. 3. Mutants defective in helper functions for sarcoma virus fixation. Virology. 58: 294-7. PMID 4362551 DOI: 10.1016/0042-6822(74)90163-9  0.339
1974 Greenberger JS, Aaronson SA. Morphologic revertants of murine sarcoma virus transformed nonproducer BALB/3T3: Selective techniques for isolation and biologic properties in vitro and in vivo Virology. 57: 339-346. PMID 4361451 DOI: 10.1016/0042-6822(74)90173-1  0.363
1974 Fishman PH, Brady RO, Bradley RM, Aaronson SA, Todaro GJ. Absence of a specific ganglioside galactosyltransferase in mouse cells transformed by murine sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 71: 298-301. PMID 4360937 DOI: 10.1073/Pnas.71.2.298  0.365
1974 Todaro GJ, Zeve V, Aaronson SA. Cell culture techniques in the search for cancer viruses of man. In Vitro. 6: 355-61. PMID 4360734 DOI: 10.1007/Bf02619073  0.343
1974 Aaronson SA, Dunn CY. Endogenous C type viruses of BALB/c cells: Frequencies of spontaneous and chemical induction Journal of Virology. 13: 181-185. PMID 4359422 DOI: 10.1128/Jvi.13.1.181-185.1974  0.366
1974 Aaronson SA, Dunn CY. High frequency C type virus induction by inhibitors of protein synthesis Science. 183: 422-423. PMID 4358074 DOI: 10.1126/Science.183.4123.422  0.387
1974 Stephenson JR, Tronick SR, Aaronson SA. Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. Cell. 3: 347-53. PMID 4140770 DOI: 10.1016/0092-8674(74)90049-X  0.399
1974 Aoki T, Stephenson JR, Aaronson SA, Hsu KC. Surface antigens of mammalian sarcoma virus-transformed nonproducer cells. Proceedings of the National Academy of Sciences of the United States of America. 71: 3445-9. PMID 4139711 DOI: 10.1073/Pnas.71.9.3445  0.325
1974 Stephenson JR, Tronick SR, Aaronson SA. Temperature-sensitive mutants of murine leukemia virus. IV. Further physiological characterization and evidence for genetic recombination. Journal of Virology. 14: 918-23. PMID 4138431 DOI: 10.1128/Jvi.14.4.918-923.1974  0.321
1974 Tronick SR, Stephenson JR, Aaronson SA. Immunological properties of two polypeptides of Mason-Pfizer monkey virus. Journal of Virology. 14: 125-32. PMID 4134467 DOI: 10.1128/Jvi.14.1.125-132.1974  0.352
1974 Stephenson JR, Tronick SR, Aaronson SA. Analysis of type specific antigenic determinants of two structural polypeptides of mouse RNA C-Type viruses. Virology. 58: 1-8. PMID 4132402 DOI: 10.1016/0042-6822(74)90135-4  0.321
1974 Tronick SR, Stephenson JR, Aaronson SA. Comparative immunological studies of RNA C-type viruses: radioimmunoassay for a low molecular weight polypeptide of woolly monkey leukemia virus. Virology. 57: 347-56. PMID 4131628 DOI: 10.1016/0042-6822(74)90174-3  0.329
1974 Stephenson JR, Greenberger JS, Aaronson SA. Oncogenicity of an endogenous C-type virus chemically activated from mouse cells in culture. Journal of Virology. 13: 237-40. PMID 4129843 DOI: 10.1128/Jvi.13.1.237-240.1974  0.385
1974 Stephenson JR, Tronick SR, Reynolds RK, Aaronson SA. Isolation and characterization of C-type viral gene products of virus-negative mouse cells. The Journal of Experimental Medicine. 139: 427-38. PMID 4129824 DOI: 10.1084/Jem.139.2.427  0.398
1974 Lee JC, Hanna MG, Ihle JN, Aaronson SA. Autogenous Immunity to Endogenous RNA Tumor Virus: Differential Reactivities of Immunoglobulins M and G to Virus Envelope Antigens Journal of Virology. 14: 773-781. DOI: 10.1128/Jvi.14.4.773-781.1974  0.316
1973 Greenberger JS, Aaronson SA. In vivo inoculation of RNA C type viruses inducing regression of experimental solid tumors Journal of the National Cancer Institute. 51: 1935-1938. PMID 4358149 DOI: 10.1093/Jnci/51.6.1935  0.37
1973 Aaronson SA, Stephenson JR. Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 70: 2055-8. PMID 4352968 DOI: 10.1073/Pnas.70.7.2055  0.382
1973 Gelb LD, Milstien JB, Martin MA, Aaronson SA. Characterization of murine leukaemia virus-specific dna present in normal mouse cells Nature New Biology. 244: 76-79. PMID 4352888 DOI: 10.1038/Newbio244076A0  0.343
1973 Aoki T, Stephenson JR, Aaronson SA. Demonstration of a cell-surface antigen associated with murine sarcoma virus by immunoelectron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 70: 742-6. PMID 4351802 DOI: 10.1073/Pnas.70.3.742  0.366
1973 Tronick SR, Stephenson JR, Aaronson SA. Immunological characterization of a low molecular weight polypeptide of murine leukemia virus. Virology. 54: 199-206. PMID 4351609 DOI: 10.1016/0042-6822(73)90129-3  0.325
1973 Stephenson JR, Wilsnack RE, Aaronson SA. Radioimmunoassay for avian C-type virus group-specific antigen: detection in normal and virus-transformed cells. Journal of Virology. 11: 893-9. PMID 4351459 DOI: 10.1128/Jvi.11.6.893-899.1973  0.37
1973 Kersey JH, Yunis EJ, Todaro GJ, Aaronson SA. HL-A Antigens of Human Tumor-Derived Cell Lines and Viral Transformed Fibroblasts in Culture Proceedings of the Society For Experimental Biology and Medicine. 143: 453-456. PMID 4350786 DOI: 10.3181/00379727-143-37341  0.335
1973 Stephenson JR, Reynolds RK, Aaronson SA. Characterization of morphologic revertants of murine and avian sarcoma virus-transformed cells. Journal of Virology. 11: 218-22. PMID 4347425 DOI: 10.1128/Jvi.11.2.218-222.1973  0.384
1973 Stephenson JR, Aaronson SA. Expression of endogenous RNA C-type virus group-specific antigens in mammalian cells. Journal of Virology. 12: 564-9. PMID 4127032 DOI: 10.1128/Jvi.12.3.564-569.1973  0.364
1973 Stephenson JR, Aaronson SA. Segregation of loci for C-type virus induction in strains of mice with high and low incidence of leukemia. Science (New York, N.Y.). 180: 865-6. PMID 4122421 DOI: 10.1126/Science.180.4088.865  0.37
1973 Aaronson SA. Biologic characterization of mammalian cells transformed by a primate sarcoma virus Virology. 52: 562-567. PMID 4122326 DOI: 10.1016/0042-6822(73)90351-6  0.37
1972 Aaronson SA, Todaro GJ, Scolnick EM. Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (New York, N.Y.). 174: 157-9. PMID 5119627 DOI: 10.1126/Science.174.4005.157  0.381
1972 Stephenson JR, Aaronson SA. Antigenic properties of murine sarcoma virus-transformed BALB-3T3 nonproducer cells. The Journal of Experimental Medicine. 135: 503-15. PMID 4550769 DOI: 10.1084/Jem.135.3.503  0.334
1972 Stephenson JR, Scolnick EM, Aaronson SA. Genetic stability of the sarcoma viruses in murine and avian sarcoma virus-transformed nonproducer cells. International Journal of Cancer. Journal International Du Cancer. 9: 577-83. PMID 4350125 DOI: 10.1002/Ijc.2910090314  0.39
1972 Stephenson JR, Aaronson SA. A genetic locus for inducibility of C-type in BALB-c cells: the effect of a nonlinked regulatory gene on detection of virus after chemical activation. Proceedings of the National Academy of Sciences of the United States of America. 69: 2798-801. PMID 4344375 DOI: 10.1073/Pnas.69.10.2798  0.379
1972 Aaronson SA, Bassin RH, Weaver C. Comparison of murine sarcoma viruses in nonproducer and S + L - -transformed cells. Journal of Virology. 9: 701-704. PMID 4336564 DOI: 10.1128/Jvi.9.4.701-704.1972  0.373
1972 Scolnick EM, Parks WP, Todaro GJ, Aaronson SA. Immunological characterization of primate C-type virus reverse transcriptases. Nature: New Biology. 235: 35-40. PMID 4332802 DOI: 10.1038/Newbio235035A0  0.303
1972 Scolnick EM, Aaronson SA, Todaro GJ. DNA synthesis by RNA-containing tumor viruses. Proceedings of the National Academy of Sciences of the United States of America. 67: 1034-41. PMID 4331715 DOI: 10.1073/Pnas.67.2.1034  0.306
1972 Scolnick EM, Stephenson JR, Aaronson SA. Isolation of temperature-sensitive mutants of murine sarcoma virus. Journal of Virology. 10: 653-7. PMID 4117345 DOI: 10.1128/Jvi.10.4.653-657.1972  0.319
1972 Stephenson JR, Aaronson SA. Genetic factors influencing C-type RNA virus induction. The Journal of Experimental Medicine. 136: 175-84. PMID 4113509 DOI: 10.1084/Jem.136.1.175  0.358
1972 Kersey JH, Gatti RA, Good RA, Aaronson SA, Todaro GJ. Susceptibility of cells from patients with primary immunodeficiency diseases to transformation by simian virus 40 Proceedings of the National Academy of Sciences of the United States of America. 69: 980-982. PMID 4112642 DOI: 10.1073/Pnas.69.4.980  0.326
1972 Parks WP, Scolnick EM, Ross J, Todaro GJ, Aaronson SA. Immunological Relationships of Reverse Transcriptases from Ribonucleic Acid Tumor Viruses Journal of Virology. 9: 110-115. DOI: 10.1128/Jvi.9.1.110-115.1972  0.363
1972 Lytle CD, Aaronson S, Harvey E. Host-cell Reactivation in Mammalian Cells International Journal of Radiation Biology. 22: 159-165. DOI: 10.1080/Rab.22.2.159.165  0.36
1971 Ross J, Scolnick EM, Todaro GJ, Aaronson SA. Separation of murine cellular and murine leukaemia virus DNA polymerases. Nature: New Biology. 231: 163-7. PMID 5281193 DOI: 10.1038/Newbio231163A0  0.351
1971 Stone LB, Scolnick E, Takemoto KK, Aaronson SA. Visna Virus: a Slow Virus with an RNA Dependent DNA Polymerase Nature. 229: 257-258. PMID 4994257 DOI: 10.1038/229257A0  0.339
1971 Scolnick EM, Aaronson SA, Todaro GJ, Parks WP. RNA dependent DNA polymerase activity in mammalian cells. Nature. 229: 318-321. PMID 4993599 DOI: 10.1038/229318A0  0.343
1971 Aaronson SA, Weaver CA. Characterization of murine sarcoma virus (Kirsten) transformation of mouse and human cells. The Journal of General Virology. 13: 245-52. PMID 4333712 DOI: 10.1099/0022-1317-13-2-245  0.381
1971 Aaronson SA. Chemical induction of focus-forming virus from nonproducer cells transformed by murine sarcoma virus Proceedings of the National Academy of Sciences of the United States of America. 68: 3069-3072. PMID 4332005 DOI: 10.1073/Pnas.68.12.3069  0.371
1971 Aaronson SA. Isolation of a rat-tropic helper virus from M-MSV-O stocks Virology. 44: 29-36. PMID 4328487 DOI: 10.1016/0042-6822(71)90149-8  0.306
1971 Gelb LD, Aaronson SA, Martin MA. Heterogeneity of murine leukemia virus in vitro DNA; detection of viral DNA in mammalian cells Science. 172: 1353-1355. PMID 4325521 DOI: 10.1126/Science.172.3990.1353  0.331
1971 Aaronson SA, Parks WP, Scolnick EM, Todaro GJ. Antibody to the RNA-dependent DNA polymerase of mammalian C-type RNA tumor viruses. Proceedings of the National Academy of Sciences of the United States of America. 68: 920-4. PMID 4325004 DOI: 10.1073/Pnas.68.5.920  0.328
1971 Aaronson SA. Common genetic alterations of RNA tumour viruses grown in human cells Nature. 230: 445-447. PMID 4324859 DOI: 10.1038/230445A0  0.343
1971 Parks WP, Todaro GJ, Scolnick EM, Aaronson SA. RNA dependent DNA polymerase in primate syncytium-forming (foamy) viruses. Nature. 229: 258-260. PMID 4323549 DOI: 10.1038/229258A0  0.32
1971 Scolnick E, Rands E, Aaronson SA, Todaro GJ. RNA-dependent DNA polymerase activity in five RNA viruses: divalent cation requirements. Proceedings of the National Academy of Sciences of the United States of America. 67: 1789-96. PMID 4322157 DOI: 10.1073/Pnas.67.4.1789  0.311
1971 Kelloff G, Aaronson SA, Gilden RV. Inactivation of murine sarcoma and leukemia viruses by ultra-violet irradiation. Virology. 42: 1133-5. PMID 4321306 DOI: 10.1016/0042-6822(70)90361-2  0.301
1971 Worthington M, Aaronson SA. Interferon System in Cells from Human Tumors and from Persons Predisposed to Cancer Infection and Immunity. 3: 424-428. DOI: 10.1128/Iai.3.3.424-428.1971  0.344
1970 Aaronson SA. Susceptibility of human cell strains to transformation by simian virus 40 and simian virus 40 deoxyribonucleic acid Journal of Virology. 6: 470-475. PMID 5497893 DOI: 10.1128/Jvi.6.4.470-475.1970  0.354
1970 Aaronson SA. Effect of ultraviolet irradiation on the survival of simian virus 40 functions in human and mouse cells Journal of Virology. 6: 393-399. PMID 5497884 DOI: 10.1128/Jvi.6.4.393-399.1970  0.367
1970 Aaronson SA, Todaro GJ, Freeman AE. Human sarcoma cells in culture. Identification by colony-forming ability on monolayers of normal cells Experimental Cell Research. 61: 1-5. PMID 5431618 DOI: 10.1016/0014-4827(70)90250-8  0.336
1970 Aaronson SA, Martin MA. Transformation of human cells with different forms of SV40 DNA Virology. 42: 848-856. PMID 4321308 DOI: 10.1016/0042-6822(70)90334-X  0.34
1970 Gerwin BI, Todaro GJ, Zeve V, Scolnick EM, Aaronson SA. Separation of RNA-dependent DNA polymerase activity from the murine leukaemia virion. Nature. 228: 435-438. PMID 4320566 DOI: 10.1038/228435A0  0.302
1970 Aaronson SA, Jainchill JL, Todaro GJ. Murine sarcoma virus transformation of BALB-3T3 cells: lack of dependence on murine leukemia virus. Proceedings of the National Academy of Sciences of the United States of America. 66: 1236-43. PMID 4319884 DOI: 10.1073/Pnas.66.4.1236  0.385
1970 Aaronson SA, Lytle CD. Decreased host cell reactivation of irradiated SV40 virus in xeroderma pigmentosum. Nature. 228: 359-361. PMID 4319741 DOI: 10.1038/228359A0  0.325
1970 Aaronson SA, Rowe SP. Nonproducer clones of murine sarcoma virus transformed BALB-3T3 cells. Virology. 42: 9-19. PMID 4318987 DOI: 10.1016/0042-6822(70)90233-3  0.381
1970 Aaronson SA, Todaro GJ. Transformation and virus growth by murine sarcoma viruses in human cells. Nature. 225: 458-459. PMID 4312364 DOI: 10.1038/225458A0  0.396
1970 Todaro GJ, Zeve V, Aaronson SA. Biological Sciences: Virus in Cell Culture derived from Human Tumour Patients Nature. 226: 1047-1049. PMID 4246031 DOI: 10.1038/2261047A0  0.32
1969 Aaronson SA, Hartley JW, Todaro GJ. Mouse leukemia virus: "spontaneous" release by mouse embryo cells after long-term in vitro cultivation. Proceedings of the National Academy of Sciences of the United States of America. 64: 87-94. PMID 4312755 DOI: 10.1073/Pnas.64.1.87  0.358
1969 Aaronson S, Todaro S. Human diploid cell transformation by DNA extracted from the tumor virus SV40. Science (New York, N.Y.). 166: 390-1. PMID 4309480 DOI: 10.1126/Science.166.3903.390  0.378
1969 Todaro GJ, Aaronson SA. Properties of clonal lines of murine sarcoma virus transformed Balb-3T3 cells. Virology. 38: 174-9. PMID 4306523 DOI: 10.1016/0042-6822(69)90140-8  0.334
1969 Aaronson SA, Todaro GJ. Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. Science (New York, N.Y.). 162: 1024-6. PMID 4301647 DOI: 10.1126/Science.162.3857.1024  0.318
1969 Jainchill JL, Aaronson SA, Todaro GJ. Murine Sarcoma and Leukemia Viruses: Assay Using Clonal Lines of Contact-Inhibited Mouse Cells Journal of Virology. 4: 549-553. DOI: 10.1128/Jvi.4.5.549-553.1969  0.326
1965 Aaronson SA, Natori Y, Tarver H. Effect of Estrogen on Uterine ATP Levels Proceedings of the Society For Experimental Biology and Medicine. 120: 9-10. PMID 5892462 DOI: 10.3181/00379727-120-30428  0.59
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