| Year |
Citation |
Score |
| 2022 |
Ferreira TR, Inbar E, Shaik J, Jeffrey BM, Ghosh K, Dobson DE, Beverley SM, Sacks D. Self-Hybridization in Leishmania major. Mbio. e0285822. PMID 36394334 DOI: 10.1128/mbio.02858-22 |
0.545 |
|
| 2022 |
Mandell MA, Beatty WL, Beverley SM. Quantitative single-cell analysis of Leishmania major amastigote differentiation demonstrates variably extended expression of the lipophosphoglycan (LPG) virulence factor in different host cell types. Plos Neglected Tropical Diseases. 16: e0010893. PMID 36302046 DOI: 10.1371/journal.pntd.0010893 |
0.667 |
|
| 2022 |
Kuhlmann FM, Key PN, Hickerson SM, Turk J, Hsu FF, Beverley SM. Inositol phosphorlyceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates. The Journal of Biological Chemistry. 102522. PMID 36162499 DOI: 10.1016/j.jbc.2022.102522 |
0.31 |
|
| 2021 |
Pant J, Samanovic M, Nelson MT, Keceli MK, Verdi J, Beverley SM, Raper J. Interplay of Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection. Plos Pathogens. 17: e1008768. PMID 34559857 DOI: 10.1371/journal.ppat.1008768 |
0.301 |
|
| 2021 |
Warren WC, Akopyants NS, Dobson DE, Hertz-Fowler C, Lye LF, Myler PJ, Ramasamy G, Shanmugasundram A, Silva-Franco F, Steinbiss S, Tomlinson C, Wilson RK, Beverley SM. Genome Assemblies across the Diverse Evolutionary Spectrum of Protozoan Parasites. Microbiology Resource Announcements. 10: e0054521. PMID 34472979 DOI: 10.1128/MRA.00545-21 |
0.561 |
|
| 2021 |
Shaik JS, Dobson DE, Sacks DL, Beverley SM. Sexual Reproductive Strategies as Resolved through Computational Methods Designed for Aneuploid Genomes. Genes. 12. PMID 33530584 DOI: 10.3390/genes12020167 |
0.491 |
|
| 2019 |
Filosa JN, Berry CT, Ruthel G, Beverley SM, Warren WC, Tomlinson C, Myler PJ, Dudkin EA, Povelones ML, Povelones M. Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites. Plos Neglected Tropical Diseases. 13: e0007570. PMID 31356610 DOI: 10.1371/Journal.Pntd.0007570 |
0.41 |
|
| 2019 |
Inbar E, Shaik J, Iantorno SA, Romano A, Nzelu CO, Owens K, Sanders MJ, Dobson D, Cotton JA, Grigg ME, Beverley SM, Sacks D. Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania. Plos Genetics. 15: e1008042. PMID 31091230 DOI: 10.1371/Journal.Pgen.1008042 |
0.606 |
|
| 2019 |
de Carvalho RVH, Andrade WA, Lima-Junior DS, Dilucca M, de Oliveira CV, Wang K, Nogueira PM, Rugani JN, Soares RP, Beverley SM, Shao F, Zamboni DS. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome. Cell Reports. 26: 429-437.e5. PMID 30625325 DOI: 10.1016/J.Celrep.2018.12.047 |
0.348 |
|
| 2018 |
Ronet C, Passelli K, Charmoy M, Scarpellino L, Myburgh E, Hauyon La Torre Y, Turco S, Mottram JC, Fasel N, Luther SA, Beverley SM, Launois P, Tacchini-Cottier F. TLR2 signaling in skin non-hematopoietic cells induces early neutrophil recruitment in response to Leishmania major infection. The Journal of Investigative Dermatology. PMID 30594488 DOI: 10.1016/J.Jid.2018.12.012 |
0.357 |
|
| 2018 |
Davenport BJ, Martin CG, Beverley SM, Orlicky DJ, Vazquez-Torres A, Morrison TE. SODB1 is essential for Leishmania major infection of Macrophages and Pathogenesis in Mice. Plos Neglected Tropical Diseases. 12: e0006921. PMID 30372439 DOI: 10.1371/Journal.Pntd.0006921 |
0.392 |
|
| 2018 |
Kohl K, Zangger H, Rossi M, Isorce N, Lye LF, Owens KL, Beverley SM, Mayer A, Fasel N. Importance of polyphosphate in the life cycle. Microbial Cell (Graz, Austria). 5: 371-384. PMID 30175107 DOI: 10.15698/Mic2018.08.642 |
0.39 |
|
| 2018 |
Robinson JI, Beverley SM. Concentration of 2'C-methyladenosine triphosphate byenables specific inhibition ofRNA virus 1 by its RNA polymerase. The Journal of Biological Chemistry. PMID 29511088 DOI: 10.1074/Jbc.Ra117.001515 |
0.34 |
|
| 2018 |
Hartley MA, Eren RO, Rossi M, Prevel F, Castiglioni P, Isorce N, Desponds C, Lye LF, Beverley SM, Drexler SK, Fasel N.
parasites block the activation of the inflammasome by inhibiting maturation of IL-1β. Microbial Cell (Graz, Austria). 5: 137-149. PMID 29487860 DOI: 10.15698/Mic2018.03.619 |
0.324 |
|
| 2018 |
Brettmann EA, Lye LF, Beverley SM. Spontaneous excision and facilitated recovery as a control for phenotypes arising from RNA interference and other dominant transgenes. Molecular and Biochemical Parasitology. PMID 29357296 DOI: 10.1016/J.Molbiopara.2018.01.004 |
0.369 |
|
| 2018 |
Eren RO, Kopelyanskiy D, Moreau D, Chapalay JB, Chambon M, Turcatti G, Lye LF, Beverley SM, Fasel N. Development of a semi-automated image-based high-throughput drug screening system. Frontiers in Bioscience (Elite Edition). 10: 242-253. PMID 28930616 DOI: 10.2741/E820 |
0.351 |
|
| 2017 |
Grybchuk D, Akopyants NS, Kostygov AY, Konovalovas A, Lye LF, Dobson DE, Zangger H, Fasel N, Butenko A, Frolov AO, Votýpka J, d'Avila-Levy CM, Kulich P, Moravcová J, Plevka P, ... ... Beverley SM, et al. Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. Proceedings of the National Academy of Sciences of the United States of America. PMID 29284754 DOI: 10.1073/Pnas.1717806115 |
0.58 |
|
| 2017 |
Iantorno SA, Durrant C, Khan A, Sanders MJ, Beverley SM, Warren WC, Berriman M, Sacks DL, Cotton JA, Grigg ME. Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage. Mbio. 8. PMID 28900023 DOI: 10.1128/Mbio.01393-17 |
0.405 |
|
| 2017 |
Guo H, Novozhilova NM, Bandini G, Turco SJ, Ferguson MAJ, Beverley SM. Genetic Metabolic Complementation establishes a requirement for GDP-Fucose in Leishmania. The Journal of Biological Chemistry. PMID 28465349 DOI: 10.1074/Jbc.M117.778480 |
0.406 |
|
| 2017 |
Rossi M, Castiglioni P, Hartley MA, Eren RO, Prével F, Desponds C, Utzschneider DT, Zehn D, Cusi MG, Kuhlmann FM, Beverley SM, Ronet C, Fasel N. Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28439019 DOI: 10.1073/Pnas.1621447114 |
0.391 |
|
| 2017 |
Matveyev AV, Alves JM, Serrano MG, Lee V, Lara AM, Barton WA, Costa-Martins AG, Beverley SM, Camargo EP, Teixeira MM, Buck GA. The Evolutionary Loss of RNAi Key Determinants in Kinetoplastids as a Multiple Sporadic Phenomenon. Journal of Molecular Evolution. PMID 28210761 DOI: 10.1007/S00239-017-9780-1 |
0.359 |
|
| 2017 |
Castiglioni P, Hartley MA, Rossi M, Prevel F, Desponds C, Utzschneider DT, Eren RO, Zangger H, Brunner L, Collin N, Zehn D, Kuhlmann FM, Beverley SM, Fasel N, Ronet C. Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid. Plos Neglected Tropical Diseases. 11: e0005240. PMID 28099431 DOI: 10.1371/Journal.Pntd.0005240 |
0.329 |
|
| 2017 |
Kuhlmann FM, Robinson JI, Bluemling GR, Ronet C, Fasel N, Beverley SM. Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096399 DOI: 10.1073/Pnas.1619114114 |
0.364 |
|
| 2017 |
Mandell MA, Beverley SM. Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096392 DOI: 10.1073/Pnas.1619265114 |
0.696 |
|
| 2016 |
Brettmann EA, Shaik JS, Zangger H, Lye LF, Kuhlmann FM, Akopyants NS, Oschwald DM, Owens KL, Hickerson SM, Ronet C, Fasel N, Beverley SM. Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response. Proceedings of the National Academy of Sciences of the United States of America. 113: 11998-12005. PMID 27790981 DOI: 10.1073/Pnas.1615085113 |
0.367 |
|
| 2016 |
Hartley MA, Bourreau E, Rossi M, Castiglioni P, Eren RO, Prevel F, Couppié P, Hickerson SM, Launois P, Beverley SM, Ronet C, Fasel N. Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A. Plos Pathogens. 12: e1005852. PMID 27658195 DOI: 10.1371/Journal.Ppat.1005852 |
0.309 |
|
| 2016 |
Eren RO, Reverte M, Rossi M, Hartley MA, Castiglioni P, Prevel F, Martin R, Desponds C, Lye LF, Drexler SK, Reith W, Beverley SM, Ronet C, Fasel N. Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence. Cell Host & Microbe. PMID 27593513 DOI: 10.1016/J.Chom.2016.08.001 |
0.358 |
|
| 2016 |
Macedo DH, Menezes-Neto A, Rugani JM, Rocha AC, Silva SO, Melo MN, Lye LF, Beverley SM, Gontijo CM, Soares RP. Low frequency of LRV1 in Leishmania braziliensis strains isolated from typical and atypical lesions in the State of Minas Gerais, Brazil. Molecular and Biochemical Parasitology. PMID 27546549 DOI: 10.1016/J.Molbiopara.2016.08.005 |
0.333 |
|
| 2016 |
Akopyants NS, Lye LF, Dobson DE, Lukeš J, Beverley SM. A Novel Bunyavirus-Like Virus of Trypanosomatid Protist Parasites. Genome Announcements. 4. PMID 27491985 DOI: 10.1128/Genomea.00715-16 |
0.58 |
|
| 2016 |
Lye LF, Akopyants NS, Dobson DE, Beverley SM. A Narnavirus-Like Element from the Trypanosomatid Protozoan Parasite Leptomonas seymouri. Genome Announcements. 4. PMID 27491984 DOI: 10.1128/Genomea.00713-16 |
0.56 |
|
| 2016 |
Akopyants NS, Lye LF, Dobson DE, Lukeš J, Beverley SM. A Narnavirus in the Trypanosomatid Protist Plant Pathogen Phytomonas serpens. Genome Announcements. 4. PMID 27469953 DOI: 10.1128/Genomea.00711-16 |
0.56 |
|
| 2016 |
Mandell MA, Beverley SM. Concomitant Immunity Induced by Persistent Leishmania major Does Not Preclude Secondary Re-Infection: Implications for Genetic Exchange, Diversity and Vaccination. Plos Neglected Tropical Diseases. 10: e0004811. PMID 27352043 DOI: 10.1371/Journal.Pntd.0004811 |
0.656 |
|
| 2016 |
Beverley SM. African Trypanosomes Find a Fat Haven. Cell Host & Microbe. 19: 748-9. PMID 27281564 DOI: 10.1016/J.Chom.2016.05.022 |
0.329 |
|
| 2016 |
Reynolds DL, Hofmeister BT, Cliffe L, Siegel TN, Anderson BA, Beverley SM, Schmitz RJ, Sabatini R. Base J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination. Molecular Microbiology. PMID 27125778 DOI: 10.1111/Mmi.13408 |
0.662 |
|
| 2016 |
Parmentier L, Cusini A, Müller N, Zangger H, Hartley MA, Desponds C, Castiglioni P, Dubach P, Ronet C, Beverley SM, Fasel N. Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus. The American Journal of Tropical Medicine and Hygiene. PMID 26834198 DOI: 10.4269/Ajtmh.15-0803 |
0.33 |
|
| 2015 |
Favila MA, Geraci NS, Jayakumar A, Hickerson S, Mostrom J, Turco SJ, Beverley SM, McDowell MA. Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells. Plos Neglected Tropical Diseases. 9: e0004238. PMID 26630499 DOI: 10.1371/Journal.Pntd.0004238 |
0.381 |
|
| 2015 |
Valdivia HO, Reis-Cunha JL, Rodrigues-Luiz GF, Baptista RP, Baldeviano GC, Gerbasi RV, Dobson DE, Pratlong F, Bastien P, Lescano AG, Beverley SM, Bartholomeu DC. Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis. Bmc Genomics. 16: 715. PMID 26384787 DOI: 10.1186/S12864-015-1928-Z |
0.584 |
|
| 2015 |
Beverley SM. Parasitology: CRISPR for Cryptosporidium. Nature. 523: 413-4. PMID 26176915 DOI: 10.1038/Nature14636 |
0.371 |
|
| 2015 |
Adaui V, Lye LF, Akopyants NS, Zimic M, Llanos-Cuentas A, Garcia L, Maes I, De Doncker S, Dobson DE, Arevalo J, Dujardin JC, Beverley SM. Association of the Endobiont Double-Stranded RNA Virus LRV1 With Treatment Failure for Human Leishmaniasis Caused by Leishmania braziliensis in Peru and Bolivia. The Journal of Infectious Diseases. PMID 26123565 DOI: 10.1093/Infdis/Jiv354 |
0.596 |
|
| 2015 |
Terrazas C, Oghumu S, Varikuti S, Martinez-Saucedo D, Beverley SM, Satoskar AR. Uncovering Leishmania-macrophage interplay using imaging flow cytometry. Journal of Immunological Methods. PMID 25967951 DOI: 10.1016/J.Jim.2015.04.022 |
0.346 |
|
| 2015 |
Damasceno JD, Beverley SM, Tosi LR. A transposon-based tool for transformation and mutagenesis in trypanosomatid protozoa. Methods in Molecular Biology (Clifton, N.J.). 1201: 235-45. PMID 25388118 DOI: 10.1007/978-1-4939-1438-8_14 |
0.36 |
|
| 2015 |
Fowlkes-Comninellis T, Beverley S. Leishmania IFT140 mutants show normal viability but lack external flagella: a tool for the study of flagellar function through the infectious cycle Cilia. 4. DOI: 10.1186/2046-2530-4-S1-P49 |
0.405 |
|
| 2014 |
Romano A, Inbar E, Debrabant A, Charmoy M, Lawyer P, Ribeiro-Gomes F, Barhoumi M, Grigg M, Shaik J, Dobson D, Beverley SM, Sacks DL. Cross-species genetic exchange between visceral and cutaneous strains of Leishmania in the sand fly vector. Proceedings of the National Academy of Sciences of the United States of America. 111: 16808-13. PMID 25385616 DOI: 10.1073/Pnas.1415109111 |
0.591 |
|
| 2014 |
Hartley MA, Drexler S, Ronet C, Beverley SM, Fasel N. The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis. Trends in Parasitology. 30: 412-22. PMID 24954794 DOI: 10.1016/J.Pt.2014.05.006 |
0.315 |
|
| 2014 |
Zangger H, Hailu A, Desponds C, Lye LF, Akopyants NS, Dobson DE, Ronet C, Ghalib H, Beverley SM, Fasel N. Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response. Plos Neglected Tropical Diseases. 8: e2836. PMID 24762979 DOI: 10.1371/Journal.Pntd.0002836 |
0.62 |
|
| 2014 |
Campos-Salinas J, Cavazzuti A, O'Valle F, Forte-Lago I, Caro M, Beverley SM, Delgado M, Gonzalez-Rey E. Therapeutic efficacy of stable analogues of vasoactive intestinal peptide against pathogens. The Journal of Biological Chemistry. 289: 14583-99. PMID 24706753 DOI: 10.1074/Jbc.M114.560573 |
0.319 |
|
| 2014 |
Beiting DP, Peixoto L, Akopyants NS, Beverley SM, Wherry EJ, Christian DA, Hunter CA, Brodsky IE, Roos DS. Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. Plos One. 9: e88398. PMID 24505488 DOI: 10.1371/Journal.Pone.0088398 |
0.404 |
|
| 2013 |
Campos-Salinas J, Caro M, Cavazzuti A, Forte-Lago I, Beverley SM, O'Valle F, Gonzalez-Rey E. Protective role of the neuropeptide urocortin II against experimental sepsis and leishmaniasis by direct killing of pathogens. Journal of Immunology (Baltimore, Md. : 1950). 191: 6040-51. PMID 24249730 DOI: 10.4049/Jimmunol.1301921 |
0.345 |
|
| 2013 |
Anderson BA, Wong IL, Baugh L, Ramasamy G, Myler PJ, Beverley SM. Kinetoplastid-specific histone variant functions are conserved in Leishmania major. Molecular and Biochemical Parasitology. 191: 53-7. PMID 24080031 DOI: 10.1016/J.Molbiopara.2013.09.005 |
0.674 |
|
| 2013 |
Inbar E, Akopyants NS, Charmoy M, Romano A, Lawyer P, Elnaiem DE, Kauffmann F, Barhoumi M, Grigg M, Owens K, Fay M, Dobson DE, Shaik J, Beverley SM, Sacks D. The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectors. Plos Genetics. 9: e1003672. PMID 23935521 DOI: 10.1371/Journal.Pgen.1003672 |
0.602 |
|
| 2013 |
Liu D, Okwor I, Mou Z, Beverley SM, Uzonna JE. Deficiency of Leishmania phosphoglycans influences the magnitude but does not affect the quality of secondary (memory) anti-Leishmania immunity. Plos One. 8: e66058. PMID 23776605 DOI: 10.1371/Journal.Pone.0066058 |
0.358 |
|
| 2013 |
Mou Z, Muleme HM, Liu D, Jia P, Okwor IB, Kuriakose SM, Beverley SM, Uzonna JE. Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion. Journal of Immunology (Baltimore, Md. : 1950). 190: 3380-9. PMID 23460745 DOI: 10.4049/Jimmunol.1202537 |
0.376 |
|
| 2013 |
Heiss C, Skowyra ML, Liu H, Klutts JS, Wang Z, Williams M, Srikanta D, Beverley SM, Azadi P, Doering TL. Unusual galactofuranose modification of a capsule polysaccharide in the pathogenic yeast Cryptococcus neoformans. The Journal of Biological Chemistry. 288: 10994-1003. PMID 23408430 DOI: 10.1074/Jbc.M112.441998 |
0.356 |
|
| 2013 |
Zangger H, Ronet C, Desponds C, Kuhlmann FM, Robinson J, Hartley MA, Prevel F, Castiglioni P, Pratlong F, Bastien P, Müller N, Parmentier L, Saravia NG, Beverley SM, Fasel N. Detection of Leishmania RNA virus in Leishmania parasites. Plos Neglected Tropical Diseases. 7: e2006. PMID 23326619 DOI: 10.1371/Journal.Pntd.0002006 |
0.339 |
|
| 2013 |
Rocha MN, Corrêa CM, Melo MN, Beverley SM, Martins-Filho OA, Madureira AP, Soares RP. An alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein. Diagnostic Microbiology and Infectious Disease. 75: 282-91. PMID 23312610 DOI: 10.1016/J.Diagmicrobio.2012.11.018 |
0.361 |
|
| 2013 |
Atayde VD, Shi H, Franklin JB, Carriero N, Notton T, Lye LF, Owens K, Beverley SM, Tschudi C, Ullu E. The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway. Molecular Microbiology. 87: 580-93. PMID 23217017 DOI: 10.1111/Mmi.12117 |
0.321 |
|
| 2013 |
Feng X, Rodriguez-Contreras D, Polley T, Lye LF, Scott D, Burchmore RJ, Beverley SM, Landfear SM. 'Transient' genetic suppression facilitates generation of hexose transporter null mutants in Leishmania mexicana. Molecular Microbiology. 87: 412-29. PMID 23170981 DOI: 10.1111/Mmi.12106 |
0.395 |
|
| 2012 |
Hartley MA, Ronet C, Zangger H, Beverley SM, Fasel N. Leishmania RNA virus: when the host pays the toll. Frontiers in Cellular and Infection Microbiology. 2: 99. PMID 22919688 DOI: 10.3389/Fcimb.2012.00099 |
0.397 |
|
| 2012 |
Franco LH, Beverley SM, Zamboni DS. Innate immune activation and subversion of Mammalian functions by leishmania lipophosphoglycan. Journal of Parasitology Research. 2012: 165126. PMID 22523640 DOI: 10.1155/2012/165126 |
0.377 |
|
| 2012 |
da Silva MF, Zampieri RA, Muxel SM, Beverley SM, Floeter-Winter LM. Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity. Plos One. 7: e34022. PMID 22479507 DOI: 10.1371/Journal.Pone.0034022 |
0.394 |
|
| 2012 |
Bruhn KW, Birnbaum R, Haskell J, Vanchinathan V, Greger S, Narayan R, Chang PL, Tran TA, Hickerson SM, Beverley SM, Wilson ME, Craft N. Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis. Clinical and Vaccine Immunology : Cvi. 19: 490-8. PMID 22323556 DOI: 10.1128/Cvi.05660-11 |
0.348 |
|
| 2011 |
Vickers TJ, Beverley SM. Folate metabolic pathways in Leishmania. Essays in Biochemistry. 51: 63-80. PMID 22023442 DOI: 10.1042/Bse0510063 |
0.343 |
|
| 2011 |
Ronet C, Beverley SM, Fasel N. Muco-cutaneous leishmaniasis in the New World: the ultimate subversion. Virulence. 2: 547-52. PMID 21971185 DOI: 10.4161/Viru.2.6.17839 |
0.359 |
|
| 2011 |
Diaz-Gonzalez R, Kuhlmann FM, Galan-Rodriguez C, Madeira da Silva L, Saldivia M, Karver CE, Rodriguez A, Beverley SM, Navarro M, Pollastri MP. The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing. Plos Neglected Tropical Diseases. 5: e1297. PMID 21886855 DOI: 10.1371/Journal.Pntd.0001297 |
0.332 |
|
| 2011 |
Ives A, Ronet C, Prevel F, Ruzzante G, Fuertes-Marraco S, Schutz F, Zangger H, Revaz-Breton M, Lye LF, Hickerson SM, Beverley SM, Acha-Orbea H, Launois P, Fasel N, Masina S. Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis. Science (New York, N.Y.). 331: 775-8. PMID 21311023 DOI: 10.1126/Science.1199326 |
0.381 |
|
| 2011 |
Wang Y, Chen Y, Xin L, Beverley SM, Carlsen ED, Popov V, Chang KP, Wang M, Soong L. Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes. Infection and Immunity. 79: 1124-33. PMID 21189319 DOI: 10.1128/Iai.00658-10 |
0.353 |
|
| 2011 |
Lye LF, Kang SO, Nosanchuk JD, Casadevall A, Beverley SM. Phenylalanine hydroxylase (PAH) from the lower eukaryote Leishmania major. Molecular and Biochemical Parasitology. 175: 58-67. PMID 20887755 DOI: 10.1016/J.Molbiopara.2010.09.004 |
0.383 |
|
| 2011 |
Feng X, Feistel T, Buffalo C, McCormack A, Kruvand E, Rodriguez-Contreras D, Akopyants NS, Umasankar PK, David L, Jardim A, Beverley SM, Landfear SM. Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes. Molecular and Biochemical Parasitology. 175: 39-48. PMID 20869991 DOI: 10.1016/J.Molbiopara.2010.08.008 |
0.348 |
|
| 2010 |
Dobson DE, Kamhawi S, Lawyer P, Turco SJ, Beverley SM, Sacks DL. Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern. Plos Pathogens. 6: e1001185. PMID 21085609 DOI: 10.1371/Journal.Ppat.1001185 |
0.615 |
|
| 2010 |
Lye LF, Owens K, Shi H, Murta SM, Vieira AC, Turco SJ, Tschudi C, Ullu E, Beverley SM. Retention and loss of RNA interference pathways in trypanosomatid protozoans. Plos Pathogens. 6: e1001161. PMID 21060810 DOI: 10.1371/Journal.Ppat.1001161 |
0.426 |
|
| 2010 |
Zhang K, Bangs JD, Beverley SM. Sphingolipids in parasitic protozoa. Advances in Experimental Medicine and Biology. 688: 238-48. PMID 20919659 DOI: 10.1007/978-1-4419-6741-1_17 |
0.368 |
|
| 2010 |
Thalhofer CJ, Graff JW, Love-Homan L, Hickerson SM, Craft N, Beverley SM, Wilson ME. In vivo imaging of transgenic Leishmania parasites in a live host. Journal of Visualized Experiments : Jove. PMID 20689512 DOI: 10.3791/1980 |
0.395 |
|
| 2010 |
Madeira da Silva L, Beverley SM. Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity. Proceedings of the National Academy of Sciences of the United States of America. 107: 11965-70. PMID 20551225 DOI: 10.1073/Pnas.1004599107 |
0.367 |
|
| 2010 |
Morales MA, Watanabe R, Dacher M, Chafey P, Osorio y Fortéa J, Scott DA, Beverley SM, Ommen G, Clos J, Hem S, Lenormand P, Rousselle JC, Namane A, Späth GF. Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage. Proceedings of the National Academy of Sciences of the United States of America. 107: 8381-6. PMID 20404152 DOI: 10.1073/Pnas.0914768107 |
0.346 |
|
| 2010 |
Lamerz AC, Damerow S, Kleczka B, Wiese M, van Zandbergen G, Lamerz J, Wenzel A, Hsu FF, Turk J, Beverley SM, Routier FH. Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major. Glycobiology. 20: 872-82. PMID 20335578 DOI: 10.1093/Glycob/Cwq045 |
0.318 |
|
| 2010 |
Secundino N, Kimblin N, Peters NC, Lawyer P, Capul AA, Beverley SM, Turco SJ, Sacks D. Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand flies. Cellular Microbiology. 12: 906-18. PMID 20088949 DOI: 10.1111/J.1462-5822.2010.01439.X |
0.788 |
|
| 2010 |
Svárovská A, Ant TH, Seblová V, Jecná L, Beverley SM, Volf P. Leishmania major glycosylation mutants require phosphoglycans (lpg2-) but not lipophosphoglycan (lpg1-) for survival in permissive sand fly vectors. Plos Neglected Tropical Diseases. 4: e580. PMID 20084096 DOI: 10.1371/Journal.Pntd.0000580 |
0.36 |
|
| 2010 |
Zhang K, Beverley SM. Phospholipid and sphingolipid metabolism in Leishmania. Molecular and Biochemical Parasitology. 170: 55-64. PMID 20026359 DOI: 10.1016/J.Molbiopara.2009.12.004 |
0.305 |
|
| 2010 |
Damasceno JD, Beverley SM, Tosi LR. A transposon toolkit for gene transfer and mutagenesis in protozoan parasites. Genetica. 138: 301-11. PMID 19763844 DOI: 10.1007/S10709-009-9406-7 |
0.411 |
|
| 2009 |
Zhang O, Wilson MC, Xu W, Hsu FF, Turk J, Kuhlmann FM, Wang Y, Soong L, Key P, Beverley SM, Zhang K. Degradation of host sphingomyelin is essential for Leishmania virulence. Plos Pathogens. 5: e1000692. PMID 20011126 DOI: 10.1371/Journal.Ppat.1000692 |
0.423 |
|
| 2009 |
Muleme HM, Reguera RM, Berard A, Azinwi R, Jia P, Okwor IB, Beverley S, Uzonna JE. Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 183: 8068-76. PMID 19923451 DOI: 10.4049/Jimmunol.0803979 |
0.43 |
|
| 2009 |
Okwor I, Liu D, Beverley SM, Uzonna JE. Inoculation of killed Leishmania major into immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process. Proceedings of the National Academy of Sciences of the United States of America. 106: 13951-6. PMID 19666482 DOI: 10.1073/Pnas.0905184106 |
0.354 |
|
| 2009 |
Liu D, Kebaier C, Pakpour N, Capul AA, Beverley SM, Scott P, Uzonna JE. Leishmania major phosphoglycans influence the host early immune response by modulating dendritic cell functions. Infection and Immunity. 77: 3272-83. PMID 19487470 DOI: 10.1128/Iai.01447-08 |
0.775 |
|
| 2009 |
Vickers TJ, Murta SM, Mandell MA, Beverley SM. The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major. Molecular and Biochemical Parasitology. 166: 142-52. PMID 19450731 DOI: 10.1016/J.Molbiopara.2009.03.009 |
0.687 |
|
| 2009 |
Nare B, Garraway LA, Vickers TJ, Beverley SM. PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major. Current Genetics. 55: 287-99. PMID 19396443 DOI: 10.1007/S00294-009-0244-Z |
0.487 |
|
| 2009 |
Reguera RM, Balaña-Fouce R, Showalter M, Hickerson S, Beverley SM. Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice. Molecular and Biochemical Parasitology. 165: 48-56. PMID 19393161 DOI: 10.1016/J.Molbiopara.2009.01.001 |
0.439 |
|
| 2009 |
Madeira da Silva L, Owens KL, Murta SM, Beverley SM. Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 106: 7583-8. PMID 19383793 DOI: 10.1073/Pnas.0901698106 |
0.4 |
|
| 2009 |
Späth GF, Schlesinger P, Schreiber R, Beverley SM. A novel role for Stat1 in phagosome acidification and natural host resistance to intracellular infection by Leishmania major. Plos Pathogens. 5: e1000381. PMID 19381261 DOI: 10.1371/Journal.Ppat.1000381 |
0.378 |
|
| 2009 |
Akopyants NS, Kimblin N, Secundino N, Patrick R, Peters N, Lawyer P, Dobson DE, Beverley SM, Sacks DL. Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector. Science (New York, N.Y.). 324: 265-8. PMID 19359589 DOI: 10.1126/Science.1169464 |
0.609 |
|
| 2009 |
Gaur U, Showalter M, Hickerson S, Dalvi R, Turco SJ, Wilson ME, Beverley SM. Leishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts. Experimental Parasitology. 122: 182-91. PMID 19328787 DOI: 10.1016/J.Exppara.2009.03.014 |
0.38 |
|
| 2009 |
Murta SM, Vickers TJ, Scott DA, Beverley SM. Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major. Molecular Microbiology. 71: 1386-401. PMID 19183277 DOI: 10.1111/J.1365-2958.2009.06610.X |
0.413 |
|
| 2009 |
Feng X, Rodriguez-Contreras D, Buffalo C, Bouwer HG, Kruvand E, Beverley SM, Landfear SM. Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana. Molecular Microbiology. 71: 369-81. PMID 19017272 DOI: 10.1111/J.1365-2958.2008.06531.X |
0.403 |
|
| 2008 |
Ng LG, Hsu A, Mandell MA, Roediger B, Hoeller C, Mrass P, Iparraguirre A, Cavanagh LL, Triccas JA, Beverley SM, Scott P, Weninger W. Migratory dermal dendritic cells act as rapid sensors of protozoan parasites. Plos Pathogens. 4: e1000222. PMID 19043558 DOI: 10.1371/Journal.Ppat.1000222 |
0.666 |
|
| 2008 |
Sutterwala SS, Hsu FF, Sevova ES, Schwartz KJ, Zhang K, Key P, Turk J, Beverley SM, Bangs JD. Developmentally regulated sphingolipid synthesis in African trypanosomes. Molecular Microbiology. 70: 281-96. PMID 18699867 DOI: 10.1111/J.1365-2958.2008.06393.X |
0.392 |
|
| 2008 |
Späth GF, McDowell MA, Beverley SM. Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45-/- mice. Experimental Parasitology. 120: 275-9. PMID 18682252 DOI: 10.1016/J.Exppara.2008.07.003 |
0.362 |
|
| 2008 |
Scott DA, Hickerson SM, Vickers TJ, Beverley SM. The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major. The Journal of Biological Chemistry. 283: 155-65. PMID 17981801 DOI: 10.1074/Jbc.M708014200 |
0.395 |
|
| 2007 |
Capul AA, Hickerson S, Barron T, Turco SJ, Beverley SM. Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major. Infection and Immunity. 75: 4629-37. PMID 17606605 DOI: 10.1128/Iai.00735-07 |
0.797 |
|
| 2007 |
Capul AA, Barron T, Dobson DE, Turco SJ, Beverley SM. Two functionally divergent UDP-Gal nucleotide sugar transporters participate in phosphoglycan synthesis in Leishmania major. The Journal of Biological Chemistry. 282: 14006-17. PMID 17347153 DOI: 10.1074/Jbc.M610869200 |
0.782 |
|
| 2007 |
Myskova J, Svobodova M, Beverley SM, Volf P. A lipophosphoglycan-independent development of Leishmania in permissive sand flies. Microbes and Infection / Institut Pasteur. 9: 317-24. PMID 17307009 DOI: 10.1016/J.Micinf.2006.12.010 |
0.402 |
|
| 2007 |
Zhang K, Pompey JM, Hsu FF, Key P, Bandhuvula P, Saba JD, Turk J, Beverley SM. Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania. The Embo Journal. 26: 1094-104. PMID 17290222 DOI: 10.1038/Sj.Emboj.7601565 |
0.307 |
|
| 2006 |
Vickers TJ, Orsomando G, de la Garza RD, Scott DA, Kang SO, Hanson AD, Beverley SM. Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence. The Journal of Biological Chemistry. 281: 38150-8. PMID 17032644 DOI: 10.1074/Jbc.M608387200 |
0.407 |
|
| 2006 |
Dobson DE, Scholtes LD, Myler PJ, Turco SJ, Beverley SM. Genomic organization and expression of the expanded SCG/L/R gene family of Leishmania major: internal clusters and telomeric localization of SCGs mediating species-specific LPG modifications. Molecular and Biochemical Parasitology. 146: 231-41. PMID 16464509 DOI: 10.1016/J.Molbiopara.2005.12.012 |
0.632 |
|
| 2006 |
Kébaïer C, Uzonna JE, Beverley SM, Scott P. Immunization with persistent attenuated Delta lpg2 Leishmania major parasites requires adjuvant to provide protective immunity in C57BL/6 mice. Infection and Immunity. 74: 777-80. PMID 16369039 DOI: 10.1128/Iai.74.1.777-780.2006 |
0.361 |
|
| 2006 |
Goswami M, Dobson DE, Beverley SM, Turco SJ. Demonstration by heterologous expression that the Leishmania SCA1 gene encodes an arabinopyranosyltransferase. Glycobiology. 16: 230-6. PMID 16272216 DOI: 10.1093/Glycob/Cwj054 |
0.569 |
|
| 2005 |
Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E, Aert R, Anupama A, Apostolou Z, Attipoe P, Bason N, Bauser C, ... ... Beverley SM, et al. The genome of the kinetoplastid parasite, Leishmania major. Science (New York, N.Y.). 309: 436-42. PMID 16020728 DOI: 10.1126/Science.1112680 |
0.626 |
|
| 2005 |
Casagrande L, Ruiz JC, Beverley SM, Cruz AK. Identification of a DNA fragment that increases mitotic stability of episomal linear DNAs in Leishmania major. International Journal For Parasitology. 35: 973-80. PMID 15996670 DOI: 10.1016/J.Ijpara.2005.04.004 |
0.334 |
|
| 2005 |
Beverley SM, Owens KL, Showalter M, Griffith CL, Doering TL, Jones VC, McNeil MR. Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens. Eukaryotic Cell. 4: 1147-54. PMID 15947206 DOI: 10.1128/Ec.4.6.1147-1154.2005 |
0.336 |
|
| 2005 |
Zhang K, Hsu FF, Scott DA, Docampo R, Turk J, Beverley SM. Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. Molecular Microbiology. 55: 1566-78. PMID 15720561 DOI: 10.1111/J.1365-2958.2005.04493.X |
0.412 |
|
| 2005 |
Segawa H, Soares RP, Kawakita M, Beverley SM, Turco SJ. Reconstitution of GDP-mannose transport activity with purified Leishmania LPG2 protein in liposomes. The Journal of Biological Chemistry. 280: 2028-35. PMID 15542612 DOI: 10.1074/Jbc.M404915200 |
0.321 |
|
| 2004 |
Boulanger N, Lowenberger C, Volf P, Ursic R, Sigutova L, Sabatier L, Svobodova M, Beverley SM, Späth G, Brun R, Pesson B, Bulet P. Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major. Infection and Immunity. 72: 7140-6. PMID 15557638 DOI: 10.1128/Iai.72.12.7140-7146.2004 |
0.37 |
|
| 2004 |
Beverley SM, Dobson DE. Flypaper for parasites. Cell. 119: 311-2. PMID 15507202 DOI: 10.1016/J.Cell.2004.10.013 |
0.584 |
|
| 2004 |
Zaph C, Uzonna J, Beverley SM, Scott P. Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites. Nature Medicine. 10: 1104-10. PMID 15448686 DOI: 10.1038/Nm1108 |
0.301 |
|
| 2004 |
Duncan RC, Salotra P, Goyal N, Akopyants NS, Beverley SM, Nakhasi HL. The application of gene expression microarray technology to kinetoplastid research. Current Molecular Medicine. 4: 611-21. PMID 15357212 DOI: 10.2174/1566524043360221 |
0.383 |
|
| 2004 |
Späth GF, Lye LF, Segawa H, Turco SJ, Beverley SM. Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies. Infection and Immunity. 72: 3622-7. PMID 15155672 DOI: 10.1128/Iai.72.6.3622-3627.2004 |
0.426 |
|
| 2004 |
Robinson KA, Goyard S, Beverley SM. In vitro shuttle mutagenesis using engineered mariner transposons. Methods in Molecular Biology (Clifton, N.J.). 270: 299-318. PMID 15153636 DOI: 10.1385/1-59259-793-9:299 |
0.35 |
|
| 2004 |
Akopyants NS, Matlib RS, Bukanova EN, Smeds MR, Brownstein BH, Stormo GD, Beverley SM. Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major. Molecular and Biochemical Parasitology. 136: 71-86. PMID 15138069 DOI: 10.1016/J.Molbiopara.2004.03.002 |
0.391 |
|
| 2004 |
Uzonna JE, Späth GF, Beverley SM, Scott P. Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response. Journal of Immunology (Baltimore, Md. : 1950). 172: 3793-7. PMID 15004184 DOI: 10.4049/Jimmunol.172.6.3793 |
0.367 |
|
| 2003 |
Zhang K, Showalter M, Revollo J, Hsu FF, Turk J, Beverley SM. Sphingolipids are essential for differentiation but not growth in Leishmania. The Embo Journal. 22: 6016-26. PMID 14609948 DOI: 10.1093/Emboj/Cdg584 |
0.376 |
|
| 2003 |
Goyard S, Segawa H, Gordon J, Showalter M, Duncan R, Turco SJ, Beverley SM. An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans. Molecular and Biochemical Parasitology. 130: 31-42. PMID 14550894 DOI: 10.1016/S0166-6851(03)00142-7 |
0.412 |
|
| 2003 |
Späth GF, Lye LF, Segawa H, Sacks DL, Turco SJ, Beverley SM. Persistence without pathology in phosphoglycan-deficient Leishmania major. Science (New York, N.Y.). 301: 1241-3. PMID 12947201 DOI: 10.1126/Science.1087499 |
0.383 |
|
| 2003 |
Coelho AC, Beverley SM, Cotrim PC. Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major. Molecular and Biochemical Parasitology. 130: 83-90. PMID 12946844 DOI: 10.1016/S0166-6851(03)00162-2 |
0.338 |
|
| 2003 |
Zufferey R, Allen S, Barron T, Sullivan DR, Denny PW, Almeida IC, Smith DF, Turco SJ, Ferguson MA, Beverley SM. Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major. The Journal of Biological Chemistry. 278: 44708-18. PMID 12944391 DOI: 10.1074/Jbc.M308063200 |
0.398 |
|
| 2003 |
Späth GF, Garraway LA, Turco SJ, Beverley SM. The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts. Proceedings of the National Academy of Sciences of the United States of America. 100: 9536-41. PMID 12869694 DOI: 10.1073/Pnas.1530604100 |
0.579 |
|
| 2003 |
Dobson DE, Mengeling BJ, Cilmi S, Hickerson S, Turco SJ, Beverley SM. Identification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major. The Journal of Biological Chemistry. 278: 28840-8. PMID 12750366 DOI: 10.1074/Jbc.M302728200 |
0.641 |
|
| 2003 |
Robinson KA, Beverley SM. Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania. Molecular and Biochemical Parasitology. 128: 217-28. PMID 12742588 DOI: 10.1016/S0166-6851(03)00079-3 |
0.405 |
|
| 2003 |
Dobson DE, Scholtes LD, Valdez KE, Sullivan DR, Mengeling BJ, Cilmi S, Turco SJ, Beverley SM. Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions. The Journal of Biological Chemistry. 278: 15523-31. PMID 12604613 DOI: 10.1074/Jbc.M301568200 |
0.606 |
|
| 2003 |
Gao LY, Groger R, Cox JS, Beverley SM, Lawson EH, Brown EJ. Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. Infection and Immunity. 71: 922-9. PMID 12540574 DOI: 10.1128/Iai.71.2.922-929.2003 |
0.373 |
|
| 2003 |
Beverley SM. Protozomics: trypanosomatid parasite genetics comes of age. Nature Reviews. Genetics. 4: 11-9. PMID 12509749 DOI: 10.1038/Nrg980 |
0.3 |
|
| 2002 |
Descoteaux A, Avila HA, Zhang K, Turco SJ, Beverley SM. Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability. The Embo Journal. 21: 4458-69. PMID 12198148 DOI: 10.1093/Emboj/Cdf447 |
0.396 |
|
| 2002 |
Lye LF, Cunningham ML, Beverley SM. Characterization of quinonoid-dihydropteridine reductase (QDPR) from the lower eukaryote Leishmania major. The Journal of Biological Chemistry. 277: 38245-53. PMID 12151409 DOI: 10.1074/Jbc.M206543200 |
0.384 |
|
| 2002 |
Breitling R, Klingner S, Callewaert N, Pietrucha R, Geyer A, Ehrlich G, Hartung R, Müller A, Contreras R, Beverley SM, Alexandrov K. Non-pathogenic trypanosomatid protozoa as a platform for protein research and production Protein Expression and Purification. 25: 209-218. PMID 12135552 DOI: 10.1016/S1046-5928(02)00001-3 |
0.366 |
|
| 2002 |
Beverley SM, Akopyants NS, Goyard S, Matlib RS, Gordon JL, Brownstein BH, Stormo GD, Bukanova EN, Hott CT, Li F, MacMillan S, Muo JN, Schwertman LA, Smeds MR, Wang Y. Putting the Leishmania genome to work: functional genomics by transposon trapping and expression profiling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 357: 47-53. PMID 11839181 DOI: 10.1098/Rstb.2001.1048 |
0.39 |
|
| 2001 |
Myler PJ, Beverley SM, Cruz AK, Dobson DE, Ivens AC, McDonagh PD, Madhubala R, Martinez-Calvillo S, Ruiz JC, Saxena A, Sisk E, Sunkin SM, Worthey E, Yan S, Stuart KD. The Leishmania genome project: new insights into gene organization and function. Medical Microbiology and Immunology. 190: 9-12. PMID 11770120 DOI: 10.1007/S004300100070 |
0.625 |
|
| 2001 |
Späth GF, Beverley SM. A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation Experimental Parasitology. 99: 97-103. PMID 11748963 DOI: 10.1006/Expr.2001.4656 |
0.419 |
|
| 2001 |
Goyard S, Tosi LRO, Gouzova J, Majors J, Beverley SM. New Mos1 mariner transposons suitable for the recovery of gene fusions in vivo and in vitro Gene. 280: 97-105. PMID 11738822 DOI: 10.1016/S0378-1119(01)00779-X |
0.328 |
|
| 2001 |
Gourley DG, Schüttelkopf AW, Leonard GA, Luba J, Hardy LW, Beverley SM, Hunter WN. Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites. Nature Structural Biology. 8: 521-5. PMID 11373620 DOI: 10.1038/88584 |
0.309 |
|
| 2001 |
Turco SJ, Späth GF, Beverley SM. Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species Trends in Parasitology. 17: 223-226. PMID 11323305 DOI: 10.1016/S1471-4922(01)01895-5 |
0.38 |
|
| 2001 |
Cunningham ML, Titus RG, Turco SJ, Beverley SM. Regulation of differentiation to the infective stage of the protozoan parasite Leishmania major by tetrahydrobiopterin Science. 292: 285-287. PMID 11303103 DOI: 10.1126/Science.1057740 |
0.377 |
|
| 2001 |
Akopyants NS, Clifton SW, Martin J, Pape D, Wylie T, Li L, Kissinger JC, Roos DS, Beverley SM. A survey of the Leishmania major Friedlin strain V1 genome by shotgun sequencing: a resource for DNA microarrays and expression profiling. Molecular and Biochemical Parasitology. 113: 337-40. PMID 11295190 DOI: 10.1016/S0166-6851(01)00227-4 |
0.422 |
|
| 2001 |
Cunningham ML, Beverley SM. Pteridine salvage throughout the Leishmania infectious cycle: Implications for antifolate chemotherapy Molecular and Biochemical Parasitology. 113: 199-213. PMID 11295174 DOI: 10.1016/S0166-6851(01)00213-4 |
0.393 |
|
| 2001 |
Streit JA, Recker TJ, Filho FG, Beverley SM, Wilson ME. Protective immunity against the protozoan Leishmania chagasi is induced by subclinical cutaneous infection with virulent but not avirulent organisms. Journal of Immunology (Baltimore, Md. : 1950). 166: 1921-9. PMID 11160240 DOI: 10.4049/Jimmunol.166.3.1921 |
0.361 |
|
| 2000 |
Mamoun CB, Gluzman IY, Beverley SM, Goldberg DE. Transposition of the Drosophila element mariner within the human malaria parasite Plasmodium falciparum Molecular and Biochemical Parasitology. 110: 405-407. PMID 11071293 DOI: 10.1016/S0166-6851(00)00268-1 |
0.331 |
|
| 2000 |
Coates CJ, Jasinskiene N, Morgan D, Tosi LRO, Beverley SM, James AA. Purified mariner (Mos1) transposase catalyzes the integration of marked elements into the germ-line of the yellow fever mosquito, Aedes aegypti Insect Biochemistry and Molecular Biology. 30: 1003-1008. PMID 10989286 DOI: 10.1016/S0965-1748(00)00110-7 |
0.343 |
|
| 2000 |
Gehring AM, Nodwell JR, Beverley SM, Losick R. Genomewide insertional mutagenesis in Streptomyces coelicolor reveals additional genes involved in morphological differentiation. Proceedings of the National Academy of Sciences of the United States of America. 97: 9642-7. PMID 10931952 DOI: 10.1073/Pnas.170059797 |
0.349 |
|
| 2000 |
Späth GF, Epstein L, Leader B, Singer SM, Avila HA, Turco SJ, Beverley SM. Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major Proceedings of the National Academy of Sciences of the United States of America. 97: 9258-9263. PMID 10908670 DOI: 10.1073/Pnas.160257897 |
0.429 |
|
| 2000 |
Goyard S, Beverley SM. Blasticidin resistance: A new independent marker for stable transfection of Leishmania Molecular and Biochemical Parasitology. 108: 249-252. PMID 10838227 DOI: 10.1016/S0166-6851(00)00210-3 |
0.401 |
|
| 2000 |
Belen Carrillo M, Gao W, Herrera M, Alroy J, Moore JB, Beverley SM, Pereira MA. Heterologous expression of Trypanosoma cruzi trans-sialidase in Leishmania major enhances virulence. Infection and Immunity. 68: 2728-34. PMID 10768966 DOI: 10.1128/Iai.68.5.2728-2734.2000 |
0.421 |
|
| 2000 |
Hong K, Ma D, Beverley SM, Turco SJ. The Leishmania GDP-mannose transporter is an autonomous, multi-specific, hexameric complex of LPG2 subunits Biochemistry. 39: 2013-2022. PMID 10684651 DOI: 10.1021/Bi992363L |
0.355 |
|
| 2000 |
Chakkalath HR, Siddiqui AA, Shankar AH, Dobson DE, Beverley SM, Titus RG. Priming of a beta-galactosidase (beta-GAL)-specific type 1 response in BALB/c mice infected with beta-GAL-transfected Leishmania major. Infection and Immunity. 68: 809-14. PMID 10639450 DOI: 10.1128/Iai.68.2.809-814.2000 |
0.581 |
|
| 2000 |
Tosi LRO, Beverley SM. cis and trans factors affecting Mos1 mariner evolution and transposition in vitro, and its potential for functional genomics Nucleic Acids Research. 28: 784-790. PMID 10637331 DOI: 10.1093/Nar/28.3.784 |
0.334 |
|
| 2000 |
Brodskyn C, Beverley SM, Titus RG. Virulent or avirulent (dhfr-ts-) Leishmania major elicit predominantly a type-1 cytokine response by human cells in vitro Clinical and Experimental Immunology. 119: 299-304. PMID 10632666 DOI: 10.1046/J.1365-2249.2000.01122.X |
0.349 |
|
| 2000 |
Sacks DL, Modi G, Rowton E, Späth G, Epstein L, Turco SJ, Beverley SM. The role of phosphoglycans in Leishmania-sand fly interactions. Proceedings of the National Academy of Sciences of the United States of America. 97: 406-11. PMID 10618431 DOI: 10.1073/Pnas.97.1.406 |
0.379 |
|
| 1999 |
Cotrim PC, Garrity LK, Beverley SM. Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection Journal of Biological Chemistry. 274: 37723-37730. PMID 10608831 DOI: 10.1074/Jbc.274.53.37723 |
0.338 |
|
| 1999 |
Lemley C, Yan S, Dole VS, Madhubala R, Cunningham ML, Beverley SM, Myler PJ, Stuart KD. The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1) Molecular and Biochemical Parasitology. 104: 93-105. PMID 10589984 DOI: 10.1016/S0166-6851(99)00132-2 |
0.399 |
|
| 1999 |
Cormack B, Rouse BT, Beverley SM. Host-microbe interactions: Fungi/viruses/parasites editorial overview Current Opinion in Microbiology. 2: 343-347. PMID 10490350 DOI: 10.1016/S1369-5274(99)80060-5 |
0.327 |
|
| 1999 |
Veras PST, Brodskyn CI, Balestieri FMP, De Freitas LAR, Ramos APS, Queiroz ARP, Barral A, Beverley SM, Barral-Netto M. A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis Memorias Do Instituto Oswaldo Cruz. 94: 491-496. PMID 10446007 DOI: 10.1590/S0074-02761999000400011 |
0.331 |
|
| 1999 |
Mamoun CB, Guzman IY, Goyard S, Beverley SM, Goldberg DE. A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum Proceedings of the National Academy of Sciences of the United States of America. 96: 8716-8720. PMID 10411941 DOI: 10.1073/Pnas.96.15.8716 |
0.402 |
|
| 1998 |
Wang Y, Dimitrov K, Garrity LK, Sazer S, Beverley SM. Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant. Molecular and Biochemical Parasitology. 96: 139-50. PMID 9851613 DOI: 10.1016/S0166-6851(98)00121-2 |
0.36 |
|
| 1998 |
Vasudevan G, Carter NS, Drew ME, Beverley SM, Sanchez MA, Seyfang A, Ullman B, Landfear SM. Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant. Proceedings of the National Academy of Sciences of the United States of America. 95: 9873-8. PMID 9707568 DOI: 10.1073/Pnas.95.17.9873 |
0.388 |
|
| 1998 |
Beverley SM, Turco SJ. Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania Trends in Microbiology. 6: 35-40. PMID 9481823 DOI: 10.1016/S0966-842X(97)01180-3 |
0.416 |
|
| 1997 |
Hardy LW, Matthews W, Nare B, Beverley SM. Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways. Experimental Parasitology. 87: 157-69. PMID 9371081 DOI: 10.1006/Expr.1997.4207 |
0.353 |
|
| 1997 |
Garraway LA, Tosi LR, Wang Y, Moore JB, Dobson DE, Beverley SM. Insertional mutagenesis by a modified in vitro Ty1 transposition system. Gene. 198: 27-35. PMID 9370261 DOI: 10.1016/S0378-1119(97)00288-6 |
0.66 |
|
| 1997 |
Gueiros-Filho FJ, Beverley SM. Trans-kingdom transposition of the Drosophila element mariner within the protozoan Leishmania Science. 276: 1716-1719. PMID 9180085 DOI: 10.1126/Science.276.5319.1716 |
0.392 |
|
| 1997 |
Nare B, Hardy LW, Beverley SM. The roles of pteridine reductase 1 and dihydrofolate reductase- thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major Journal of Biological Chemistry. 272: 13883-13891. PMID 9153248 DOI: 10.1074/Jbc.272.21.13883 |
0.385 |
|
| 1997 |
Garcia MR, Graham S, Harris RA, Beverley SM, Kaye PM. Epitope cleavage by Leishmania endopeptidase(s) limits the efficiency of the exogenous pathway of major histocompatibility complex class I-associated antigen presentation European Journal of Immunology. 27: 1005-1013. PMID 9130657 DOI: 10.1002/Eji.1830270430 |
0.349 |
|
| 1997 |
Racoosin EL, Beverley SM. Leishmania major: Promastigotes induce expression of a subset of chemokine genes in murine macrophages Experimental Parasitology. 85: 283-295. PMID 9085925 DOI: 10.1006/Expr.1996.4139 |
0.398 |
|
| 1997 |
Flaspohler JA, Rickoll WL, Beverley SM, Parsons M. Functional identification of a Leishmania gene related to the peroxin 2 gene reveals common ancestry of glycosomes and peroxisomes Molecular and Cellular Biology. 17: 1093-1101. PMID 9032236 DOI: 10.1128/Mcb.17.3.1093 |
0.371 |
|
| 1997 |
Ma D, Russell DG, Beverley SM, Turco SJ. Golgi GDP-mannose uptake requires leishmania LPG2: A member of a eukaryotic family of putative nucleotide-sugar transporters Journal of Biological Chemistry. 272: 3799-3805. PMID 9013638 DOI: 10.1074/Jbc.272.6.3799 |
0.353 |
|
| 1997 |
NARE B, LUBA J, HARDY LW, BEVERLEY S. New approaches to Leishmania chemotherapy: pteridine
reductase 1 (PTR1) as a target and modulator of antifolate sensitivity Parasitology. 114: 101-110. DOI: 10.1017/S0031182097001133 |
0.351 |
|
| 1996 |
Beverley SM. Hijacking the cell: Parasites in the driver's seat Cell. 87: 787-789. PMID 8945504 DOI: 10.1016/S0092-8674(00)81984-4 |
0.44 |
|
| 1996 |
Ma D, Beverley SM, Turco SJ. Leishmania donovani possess a NADPH-dependent alkylglycerol cleavage enzyme Biochemical and Biophysical Research Communications. 227: 885-889. PMID 8886025 DOI: 10.1006/Bbrc.1996.1600 |
0.323 |
|
| 1996 |
Gueiros-Filho FJ, Beverley SM. Selection against the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus as a probe of genetic alterations in Leishmania major Molecular and Cellular Biology. 16: 5655-5663. PMID 8816478 DOI: 10.1128/Mcb.16.10.5655 |
0.36 |
|
| 1996 |
Ha DS, Schwarz JK, Turco SJ, Beverley SM. Use of the green fluorescent protein as a marker in transfected Leishmania. Molecular and Biochemical Parasitology. 77: 57-64. PMID 8784772 DOI: 10.1016/0166-6851(96)02580-7 |
0.339 |
|
| 1995 |
Beverley SM, Turco SJ. Identification of genes mediating lipophosphoglycan biosynthesis by functional complementation of Leishmania donovani mutants Annals of Tropical Medicine and Parasitology. 89: 11-17. PMID 8745922 DOI: 10.1080/00034983.1995.11813009 |
0.413 |
|
| 1995 |
Cupolillo E, Grimaldi G, Momen H, Beverley SM. Intergenic region typing (IRT): A rapid molecular approach to the characterization and evolution of Leishmania Molecular and Biochemical Parasitology. 73: 145-155. PMID 8577322 DOI: 10.1016/0166-6851(95)00108-D |
0.393 |
|
| 1995 |
Descoteaux A, Luo Y, Turco SJ, Beverley SM. A specialized pathway affecting virulence glycoconjugates of leishmania Science. 269: 1869-1872. PMID 7569927 DOI: 10.1126/Science.7569927 |
0.405 |
|
| 1995 |
Titus RG, Gueiros-Filho FJ, De Freitas LAR, Beverley SM. Development of a safe live Leishmania vaccine line by gene replacement Proceedings of the National Academy of Sciences of the United States of America. 92: 10267-10271. PMID 7479765 DOI: 10.1073/Pnas.92.22.10267 |
0.374 |
|
| 1994 |
Pimenta PF, Saraiva EM, Rowton E, Modi GB, Garraway LA, Beverley SM, Turco SJ, Sacks DL. Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan. Proceedings of the National Academy of Sciences of the United States of America. 91: 9155-9. PMID 8090785 DOI: 10.1073/Pnas.91.19.9155 |
0.542 |
|
| 1994 |
Uliana SRB, Nelson K, Beverley SM, Camargo EP, Floeter-Winter LM. Discrimination amongst leishmania by polymerase chain reaction and hybridization with small subunit ribosomal DNA derived oligonucleotides Journal of Eukaryotic Microbiology. 41: 324-330. PMID 8087103 DOI: 10.1111/J.1550-7408.1994.Tb06085.X |
0.355 |
|
| 1994 |
Bello AR, Nare B, Freedman D, Hardy L, Beverley SM. PTR1: A reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major Proceedings of the National Academy of Sciences of the United States of America. 91: 11442-11446. PMID 7972081 DOI: 10.1073/Pnas.91.24.11442 |
0.405 |
|
| 1994 |
Callahan HL, Roberts WL, Rainey PM, Beverley SM. The PGPA gene of Leishmania major mediates antimony (SbIII) resistance by decreasing influx and not by increasing efflux. Molecular and Biochemical Parasitology. 68: 145-9. PMID 7891738 DOI: 10.1016/0166-6851(94)00154-5 |
0.362 |
|
| 1993 |
López JA, LeBowitz JH, Beverley SM, Rammensee HG, Overath P. Leishmania mexicana promastigotes induce cytotoxic T lymphocytes in vivo that do not recognize infected macrophages European Journal of Immunology. 23: 217-223. PMID 8419175 DOI: 10.1002/Eji.1830230134 |
0.356 |
|
| 1993 |
Cruz AK, Titus R, Beverley SM. Plasticity in chromosome number and testing of essential genes in Leishmania by targeting Proceedings of the National Academy of Sciences of the United States of America. 90: 1599-1603. PMID 8381972 DOI: 10.1073/Pnas.90.4.1599 |
0.367 |
|
| 1993 |
Ryan KA, Garraway LA, Descoteaux A, Turco SJ, Beverley SM. Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania Proceedings of the National Academy of Sciences of the United States of America. 90: 8609-8613. PMID 8378337 DOI: 10.1073/Pnas.90.18.8609 |
0.593 |
|
| 1993 |
Ryan KA, Dasgupta S, Beverley SM. Shuttle cosmid vectors for the trypanosomatid parasite Leishmania Gene. 131: 145-150. PMID 8370535 DOI: 10.1016/0378-1119(93)90684-U |
0.404 |
|
| 1993 |
Fernandes AP, Nelson K, Beverley SM. Evolution of nuclear ribosomal RNAs in kinetoplastid protozoa: Perspectives on the age and origins of parasitism Proceedings of the National Academy of Sciences of the United States of America. 90: 11608-11612. PMID 8265597 DOI: 10.1073/Pnas.90.24.11608 |
0.344 |
|
| 1993 |
Beverley SM, Clayton CE. Transfection of Leishmania and Trypanosoma brucei by electroporation Methods in Molecular Biology (Clifton, N.J.). 21: 333-348. PMID 8220725 DOI: 10.1385/0-89603-239-6:333 |
0.346 |
|
| 1993 |
Freedman DJ, Beverley SM. Two more independent selectable markers for stable transfection of Leishmania. Molecular and Biochemical Parasitology. 62: 37-44. PMID 8114824 DOI: 10.1016/0166-6851(93)90175-W |
0.369 |
|
| 1993 |
Kaye PM, Coburn C, McCrossan M, Beverley SM. Antigens targeted to the Leishmania phagolysosome are processed for CD4+ T cell recognition European Journal of Immunology. 23: 2311-2319. PMID 8103748 DOI: 10.1002/Eji.1830230939 |
0.325 |
|
| 1992 |
McMahon-Pratt D, Traub-Cseko Y, Lohman KL, Rogers DD, Beverley SM. Loss of the GP46/M-2 surface membrane glycoprotein gene family in the Leishmania braziliensis complex Molecular and Biochemical Parasitology. 50: 151-160. PMID 1542309 DOI: 10.1016/0166-6851(92)90252-F |
0.352 |
|
| 1992 |
Briones MRS, Nelson K, Beverley SM, Affonso HT, Camargo EP, Floeter-Winter LM. Leishmania tarentolae taxonomic relatedness inferred from phylogenetic analysis of the small subunit ribosomal RNA gene Molecular and Biochemical Parasitology. 53: 121-127. PMID 1501631 DOI: 10.1016/0166-6851(92)90014-B |
0.372 |
|
| 1992 |
Wilson K, Beverley SM, Ullman B. Stable amplification of a linear extrachromosomal DNA in mycophenolic acid-resistant Leishmania donovani Molecular and Biochemical Parasitology. 55: 197-206. PMID 1359409 DOI: 10.1016/0166-6851(92)90140-F |
0.329 |
|
| 1991 |
LeBowitz JH, Coburn CM, Beverley SM. Simultaneous transient expression assays of the trypanosomatid parasite Leishmania using β-galactosidase and β-glucuronidase as reporter enzymes Gene. 103: 119-123. PMID 1908808 DOI: 10.1016/0378-1119(91)90402-W |
0.352 |
|
| 1991 |
Coburn CM, Otteman KM, McNeely T, Turco SJ, Beverley SM. Stable DNA transfection of a wide range of trypanosomatids Molecular and Biochemical Parasitology. 46: 169-179. PMID 1906580 DOI: 10.1016/0166-6851(91)90210-W |
0.407 |
|
| 1991 |
Panton LJ, Tesh RB, Nadeau KC, Beverley SM. A test for genetic exchange in mixed infections of Leishmania major in the sand fly Phlebotomus papatasi Journal of Protozoology. 38: 224-228. PMID 1880760 DOI: 10.1111/J.1550-7408.1991.Tb04433.X |
0.375 |
|
| 1991 |
Beverley SM. Gene amplification in Leishmania Annual Review of Microbiology. 45: 417-444. PMID 1741620 DOI: 10.1146/Annurev.Mi.45.100191.002221 |
0.367 |
|
| 1991 |
Cruz A, Coburn CM, Beverley SM. Double targeted gene replacement for creating null mutants Proceedings of the National Academy of Sciences of the United States of America. 88: 7170-7174. PMID 1651496 DOI: 10.1073/Pnas.88.16.7170 |
0.371 |
|
| 1990 |
Nelson K, Alonso G, Langer PJ, Beverley SM. Sequence of the dihydrofolate reductase-thymidylate synthase (DHFR-TS) gene of Leishmania amazonensis. Nucleic Acids Research. 18: 2819. PMID 2339068 DOI: 10.1093/Nar/18.9.2819 |
0.33 |
|
| 1990 |
Kapler GM, Coburn CM, Beverley SM. Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression Molecular and Cellular Biology. 10: 1084-1094. PMID 2304458 DOI: 10.1128/Mcb.10.3.1084 |
0.735 |
|
| 1990 |
Kapler GM, Zhang K, Beverley SM. Nuclease mapping and DNA sequence analysis of transcripts from the dihydrofolate reductase-thymidylate synthase (R) region of Leishmania major Nucleic Acids Research. 18: 6399-6408. PMID 2243782 DOI: 10.1093/Nar/18.21.6399 |
0.715 |
|
| 1990 |
Cruz A, Beverley SM. Gene replacement in parasitic protozoa Nature. 348: 171-173. PMID 2234081 DOI: 10.1038/348171A0 |
0.402 |
|
| 1990 |
Beverley SM, Coburn CM. Recurrent de novo appearance of small linear DNAs in Leishmania major and relationship to extra-chromosomal DNAs in other species Molecular and Biochemical Parasitology. 42: 133-141. PMID 2233897 DOI: 10.1016/0166-6851(90)90121-2 |
0.322 |
|
| 1990 |
LeBowitz JH, Coburn CM, McMahon-Pratt D, Beverley SM. Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes Proceedings of the National Academy of Sciences of the United States of America. 87: 9736-9740. PMID 2124701 DOI: 10.1073/Pnas.87.24.9736 |
0.45 |
|
| 1989 |
Beverley SM, Petrillo-Peixoto M. Naturally-occurring gene amplifications conferring drug resistance in Leishmania tarentolae. Memorias Do Instituto Oswaldo Cruz. 330-3. PMID 3253502 DOI: 10.1590/S0074-02761988000500017 |
0.308 |
|
| 1989 |
Petrillo-Peixoto ML, Beverley SM. Amplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major. Molecular and Cellular Biology. 8: 5188-99. PMID 3244352 DOI: 10.1128/Mcb.8.12.5188 |
0.345 |
|
| 1989 |
Ellenberger TE, Beverley SM. Multiple drug resistance and conservative amplification of the H region in Leishmania major. The Journal of Biological Chemistry. 264: 15094-103. PMID 2768255 |
0.581 |
|
| 1989 |
Petrillo-Peixoto ML, Beverley SM. Amplification of a new region of DNA in an unselected laboratory stock of L. tarentolae: the T region Journal of Protozoology. 36: 257-261. PMID 2732966 DOI: 10.1111/J.1550-7408.1989.Tb05359.X |
0.335 |
|
| 1989 |
Kapler GM, Beverley SM. Transcriptional mapping of the amplified region encoding the dihydrofolate reductase-thymidylate synthase of Leishmania major reveals a high density of transcripts, including overlapping and antisense RNAs Molecular and Cellular Biology. 9: 3959-3972. PMID 2476667 DOI: 10.1128/Mcb.9.9.3959 |
0.686 |
|
| 1989 |
Ellenberger TE, Wright JE, Rosowsky A, Beverley SM. Wild-type and drug-resistant Leishmania major hydrolyze methotrexate to N-10-methyl-4-deoxy-4-aminopteroate without accumulation of methotrexate polyglutamates. The Journal of Biological Chemistry. 264: 15960-6. PMID 2476435 |
0.572 |
|
| 1988 |
Peixoto MP, Beverley SM. In vitro activity of sulfonamides and sulfones against Leishmania major promastigotes. Antimicrobial Agents and Chemotherapy. 31: 1575-8. PMID 3435106 DOI: 10.1128/Aac.31.10.1575 |
0.304 |
|
| 1987 |
Ellenberger TE, Beverley SM. Reductions in methotrexate and folate influx in methotrexate-resistant lines of Leishmania major are independent of R or H region amplification. The Journal of Biological Chemistry. 262: 13501-6. PMID 3654626 |
0.585 |
|
| 1987 |
Kapler GM, Zhang K, Beverley SM. Sequence and S1 nuclease mapping of the 5′ region of the dihydrofolate reductasethymidylate synthase gene of Leishmania major Nucleic Acids Research. 15: 3369-3383. PMID 3554143 DOI: 10.1093/Nar/15.8.3369 |
0.72 |
|
| 1987 |
Beverley SM, Ismach RB, Pratt DM. Evolution of the genus Leishmania as revealed by comparisons of nuclear DNA restriction fragment patterns. Proceedings of the National Academy of Sciences of the United States of America. 84: 484-8. PMID 3025876 DOI: 10.1073/Pnas.84.2.484 |
0.309 |
|
| 1987 |
Ellenberger TE, Beverley SM. Biochemistry and regulation of folate and methotrexate transport in Leishmania major. The Journal of Biological Chemistry. 262: 10053-8. PMID 2886498 |
0.584 |
|
| 1986 |
Beverley SM, Ellenberger TE, Cordingley JS. Primary structure of the gene encoding the bifunctional dihydrofolate reductase-thymidylate synthase of Leishmania major. Proceedings of the National Academy of Sciences of the United States of America. 83: 2584-8. PMID 3458220 DOI: 10.1073/Pnas.83.8.2584 |
0.664 |
|
| 1985 |
Beverley SM, Wilson AC. Ancient origin for Hawaiian Drosophilinae inferred from protein comparisons. Proceedings of the National Academy of Sciences of the United States of America. 82: 4753-7. PMID 3860822 DOI: 10.1073/Pnas.82.14.4753 |
0.454 |
|
| 1984 |
Beverley SM, Coderre JA, Santi DV, Schimke RT. Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization. Cell. 38: 431-9. PMID 6467372 DOI: 10.1016/0092-8674(84)90498-7 |
0.548 |
|
| 1984 |
Beverley SM, Wilson AC. Molecular evolution in Drosophila and the higher Diptera II. A time scale for fly evolution. Journal of Molecular Evolution. 21: 1-13. PMID 6442354 DOI: 10.1007/Bf02100622 |
0.46 |
|
| 1984 |
Schimke RT, Beverley S, Brown P, Cassin R, Federspiel N, Gasser C, Hill A, Johnston R, Mariani B, Mosse E. Gene amplification and drug resistance in cultured animal cells. Cancer Treatment Reviews. 11: 9-17. PMID 6375865 DOI: 10.1016/0305-7372(84)90038-0 |
0.569 |
|
| 1983 |
Johnston RN, Beverley SM, Schimke RT. Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting. Proceedings of the National Academy of Sciences of the United States of America. 80: 3711-5. PMID 6574509 DOI: 10.1073/Pnas.80.12.3711 |
0.547 |
|
| 1983 |
Coderre JA, Beverley SM, Schimke RT, Santi DV. Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica. Proceedings of the National Academy of Sciences of the United States of America. 80: 2132-6. PMID 6572966 DOI: 10.1073/Pnas.80.8.2132 |
0.561 |
|
| 1982 |
Beverley SM, Wilson AC. Molecular evolution of Drosophila and higher Diptera. I. Micro-complement fixation studies of a larval hemolymph protein. Journal of Molecular Evolution. 18: 251-64. PMID 6808147 DOI: 10.1007/Bf01734103 |
0.48 |
|
| 1981 |
Brown PC, Beverley SM, Schimke RT. Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines. Molecular and Cellular Biology. 1: 1077-83. PMID 6287217 DOI: 10.1128/Mcb.1.12.1077 |
0.547 |
|
| 1980 |
Zimmer EA, Martin SL, Beverley SM, Kan YW, Wilson AC. Rapid duplication and loss of genes coding for the alpha chains of hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 77: 2158-62. PMID 6929543 DOI: 10.1073/Pnas.77.4.2158 |
0.641 |
|
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