| Year |
Citation |
Score |
| 2024 |
Sutton TB, Sawyer DL, Naila T, Sweasy JB, Tomkinson AE, Delaney S. Global screening of base excision repair in nucleosome core particles. Dna Repair. 144: 103777. PMID 39476546 DOI: 10.1016/j.dnarep.2024.103777 |
0.674 |
|
| 2024 |
Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Huang X, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, et al. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. Molecular Cell. PMID 39383878 DOI: 10.1016/j.molcel.2024.09.020 |
0.513 |
|
| 2024 |
Bhandari SK, Wiest N, Sallmyr A, Du R, Tomkinson AE. Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication. Nucleic Acids Research. PMID 39106163 DOI: 10.1093/nar/gkae672 |
0.701 |
|
| 2024 |
Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. Biorxiv : the Preprint Server For Biology. PMID 38559022 DOI: 10.1101/2024.03.12.584665 |
0.507 |
|
| 2024 |
Kodavati M, Wang H, Guo W, Mitra J, Hegde PM, Provasek V, Rao VHM, Vedula I, Zhang A, Mitra S, Tomkinson AE, Hamilton DJ, Van Den Bosch L, Hegde ML. FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature Communications. 15: 2156. PMID 38461154 DOI: 10.1038/s41467-024-45978-6 |
0.423 |
|
| 2023 |
Sallmyr A, Khattri Bhandari S, Naila T, Tomkinson AE. Mammalian DNA ligases; roles in maintaining genome integrity. Journal of Molecular Biology. 168276. PMID 37714297 DOI: 10.1016/j.jmb.2023.168276 |
0.823 |
|
| 2023 |
Hegde M, Manohar K, Wang H, Gao W, Mitra J, Hegde P, Provasek V, Rao V, Vedula I, Zhang A, Mitra S, Tomkinson A, Bosch LVD, Hamilton D. FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration. Research Square. PMID 37502965 DOI: 10.21203/rs.3.rs-3152718/v1 |
0.443 |
|
| 2023 |
Bilkis R, Lake RJ, Cooper KL, Tomkinson A, Fan HY. The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions. Nucleic Acids Research. PMID 37326017 DOI: 10.1093/nar/gkad515 |
0.724 |
|
| 2023 |
Chen S, Vogt A, Lee L, Naila T, McKeown R, Tomkinson AE, Lees-Miller SP, He Y. Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. Science Advances. 9: eadg2838. PMID 37256947 DOI: 10.1126/sciadv.adg2838 |
0.74 |
|
| 2023 |
Bhandari SK, Wiest N, Sallmyr A, Du R, Ferry L, Defossez PA, Tomkinson AE. Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1. Scientific Reports. 13: 4363. PMID 36928068 DOI: 10.1038/s41598-023-31367-4 |
0.623 |
|
| 2022 |
Rashid I, Tsai MS, Sverzhinsky A, Hlaing AS, Shih B, Thwin AC, Lin JG, Maw SS, Pascal JM, Tomkinson AE. Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cells. Methods in Molecular Biology (Clifton, N.J.). 2444: 243-269. PMID 35290642 DOI: 10.1007/978-1-0716-2063-2_15 |
0.422 |
|
| 2021 |
Sverzhinsky A, Tomkinson AE, Pascal JM. Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Structure (London, England : 1993). PMID 34838188 DOI: 10.1016/j.str.2021.11.002 |
0.802 |
|
| 2021 |
Ali R, Alabdullah M, Algethami M, Alblihy A, Miligy I, Shoqafi A, Mesquita KA, Abdel-Fatah T, Chan SY, Chiang PW, Mongan NP, Rakha EA, Tomkinson AE, Madhusudan S. Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers. Theranostics. 11: 8350-8361. PMID 34373746 DOI: 10.7150/thno.51456 |
0.389 |
|
| 2021 |
Rashid I, Hammel M, Sverzhinsky A, Tsai MS, Pascal JM, Tainer JA, Tomkinson AE. Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. The Journal of Biological Chemistry. 100921. PMID 34181949 DOI: 10.1016/j.jbc.2021.100921 |
0.729 |
|
| 2021 |
Chen S, Lee L, Naila T, Fishbain S, Wang A, Tomkinson AE, Lees-Miller SP, He Y. Structural basis of long-range to short-range synaptic transition in NHEJ. Nature. PMID 33854234 DOI: 10.1038/s41586-021-03458-7 |
0.788 |
|
| 2020 |
Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Research. PMID 33330937 DOI: 10.1093/nar/gkaa1188 |
0.604 |
|
| 2020 |
Zhao B, Naila T, Lieber MR, Tomkinson AE. NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV. Nucleic Acids Research. PMID 33264406 DOI: 10.1093/nar/gkaa1118 |
0.765 |
|
| 2020 |
Matsumoto Y, Brooks RC, Sverzhinsky A, Pascal JM, Tomkinson AE. Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation. Journal of Molecular Biology. PMID 33157085 DOI: 10.1016/j.jmb.2020.10.032 |
0.75 |
|
| 2020 |
Sallmyr A, Rashid I, Bhandari SK, Naila T, Tomkinson AE. Human DNA ligases in replication and repair. Dna Repair. 93: 102908. PMID 33087274 DOI: 10.1016/j.dnarep.2020.102908 |
0.771 |
|
| 2020 |
Eckelmann BJ, Bacolla A, Wang H, Ye Z, Guerrero EN, Jiang W, El-Zein R, Hegde ML, Tomkinson AE, Tainer JA, Mitra S. XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells. Nar Cancer. 2: zcaa013. PMID 32776008 DOI: 10.1093/narcan/zcaa013 |
0.537 |
|
| 2020 |
Oh DY, Matsumoto Y, Kitajiri SI, Kim NKD, Young Kim M, Reum Kim A, Lee M, Lee C, Tomkinson AE, Katsuno T, Young Kim S, Shin HW, Hee Han J, Lee S, Park WY, et al. POLD1 variants leading to reduced polymerase activity can cause hearing loss without syndromic features. Human Mutation. PMID 31944473 DOI: 10.1002/humu.23984 |
0.382 |
|
| 2019 |
Tomkinson AE, Naila T, Khattri Bhandari S. Altered DNA ligase activity in human disease. Mutagenesis. PMID 31630206 DOI: 10.1093/mutage/gez026 |
0.813 |
|
| 2019 |
Roth BM, Varney KM, Yang H, Weber DJ, Tomkinson AE. H, C, and N backbone resonance assignments of the human DNA ligase 3 DNA-binding domain (residues 257-477). Biomolecular Nmr Assignments. PMID 31093909 DOI: 10.1007/S12104-019-09896-9 |
0.771 |
|
| 2019 |
Wiest NE, Tomkinson AE. SUMOning the base excision repair machinery for differentiation. The Embo Journal. 38. PMID 30545824 DOI: 10.15252/embj.2018101147 |
0.326 |
|
| 2018 |
Wang H, Guo W, Mitra J, Hegde PM, Vandoorne T, Eckelmann BJ, Mitra S, Tomkinson AE, Van Den Bosch L, Hegde ML. Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis. Nature Communications. 9: 3683. PMID 30206235 DOI: 10.1038/S41467-018-06111-6 |
0.616 |
|
| 2018 |
Sallmyr A, Tomkinson AE. Repair of DNA double-strand breaks by mammalian alternative end-joining pathways. The Journal of Biological Chemistry. PMID 29530982 DOI: 10.1074/jbc.TM117.000375 |
0.573 |
|
| 2017 |
Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Erratum to "Structure-activity relationships among DNA ligase inhibitors; characterization of a selective uncompetitive DNA ligase I inhibitor" [DNA Repair 60C (2017) 29-39]. Dna Repair. PMID 29273192 DOI: 10.1016/J.Dnarep.2017.12.001 |
0.727 |
|
| 2017 |
Howes TRL, Sallymr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. Dna Repair. 60: 29-39. PMID 29078112 DOI: 10.1016/J.Dnarep.2017.10.002 |
0.468 |
|
| 2017 |
Wiest NE, Houghtaling S, Sanchez JC, Tomkinson AE, Osley MA. The SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast. Nucleic Acids Research. PMID 28398510 DOI: 10.1093/Nar/Gkx221 |
0.743 |
|
| 2017 |
Cannan WJ, Rashid I, Tomkinson AE, Wallace SS, Pederson DS. The Human DNA Ligase IIIα-X-ray Repair Cross-complementing Protein 1 Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA. The Journal of Biological Chemistry. PMID 28184006 DOI: 10.1074/Jbc.M116.736728 |
0.711 |
|
| 2016 |
Hammel M, Yu Y, Radhakrishnan SK, Chokshi C, Tsai MS, Matsumoto Y, Kuzdovich M, Remesh SG, Fang S, Tomkinson AE, Lees-Miller SP, Tainer JA. An Intrinsically Disordered APLF Links Ku, DNA-PKcs and XRCC4-DNA Ligase IV in an Extended Flexible Non-Homologous End Joining Complex. The Journal of Biological Chemistry. PMID 27875301 DOI: 10.1074/Jbc.M116.751867 |
0.694 |
|
| 2016 |
Peng Z, Liao Z, Matsumoto Y, Yang A, Tomkinson AE. Human DNA Ligase I Interacts with and is Targeted for Degradation by the DCAF7 Specificity Factor of the CUL4-DDB1 Ubiquitin Ligase Complex. The Journal of Biological Chemistry. PMID 27573245 DOI: 10.1074/Jbc.M116.746198 |
0.789 |
|
| 2016 |
Sallmyr A, Matsumoto Y, Roginskaya VY, Van Houten B, Tomkinson AE. Inhibiting mitochondrial DNA ligase IIIα activates caspase 1-dependent apoptosis in cancer cells. Cancer Research. PMID 27503931 DOI: 10.1158/0008-5472.CAN-15-3243 |
0.44 |
|
| 2016 |
Greco GE, Matsumoto Y, Brooks RC, Lu Z, Lieber MR, Tomkinson AE. SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV. Dna Repair. 43: 18-23. PMID 27235626 DOI: 10.1016/j.dnarep.2016.04.004 |
0.754 |
|
| 2016 |
Slean MM, Panigrahi GB, Castel AL, Pearson AB, Tomkinson AE, Pearson CE. Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks. Dna Repair. PMID 27155933 DOI: 10.1016/J.Dnarep.2016.04.002 |
0.692 |
|
| 2016 |
Greco GE, Conrad ZA, Johnston AM, Li Q, Tomkinson AE. Synthesis and structure determination of SCR7, a DNA ligase inhibitor Tetrahedron Letters. 57: 3204-3207. DOI: 10.1016/j.tetlet.2016.06.037 |
0.533 |
|
| 2015 |
Hegde PM, Dutta A, Sengupta S, Mitra J, Adhikari S, Tomkinson AE, Li GM, Boldogh I, Hazra TK, Mitra S, Hegde ML. The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: Dominant Negative Function of CTD. The Journal of Biological Chemistry. PMID 26134572 DOI: 10.1074/Jbc.M115.642918 |
0.687 |
|
| 2015 |
Kukshal V, Kim IK, Hura GL, Tomkinson AE, Tainer JA, Ellenberger T. Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining. Nucleic Acids Research. 43: 7021-31. PMID 26130724 DOI: 10.1093/Nar/Gkv652 |
0.808 |
|
| 2015 |
Yang H, Matsumoto Y, Trujillo KM, Lees-Miller SP, Osley MA, Tomkinson AE. Role of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joining. Dna Repair. 31: 1-10. PMID 25942368 DOI: 10.1016/J.Dnarep.2015.04.003 |
0.744 |
|
| 2015 |
Matsumoto Y, Rodriguez V, Whitford TA, Beeharry N, Ide H, Tomkinson AE. Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells. Oncoscience. 2: 272-84. PMID 25897430 |
0.308 |
|
| 2015 |
Matsumoto Y, Rodriguez V, Whitford TA, Beeharry N, Ide H, Tomkinson AE. Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells Oncoscience. 2: 272-284. DOI: 10.18632/oncoscience.125 |
0.307 |
|
| 2014 |
Ghezraoui H, Piganeau M, Renouf B, Renaud JB, Sallmyr A, Ruis B, Oh S, Tomkinson AE, Hendrickson EA, Giovannangeli C, Jasin M, Brunet E. Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining. Molecular Cell. 55: 829-42. PMID 25201414 DOI: 10.1016/J.Molcel.2014.08.002 |
0.3 |
|
| 2014 |
Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M. Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination. The Journal of Biological Chemistry. 289: 22739-48. PMID 24923443 DOI: 10.1074/Jbc.M114.550459 |
0.725 |
|
| 2013 |
Tomkinson AE, Howes TR, Wiest NE. DNA ligases as therapeutic targets. Translational Cancer Research. 2. PMID 24224145 |
0.626 |
|
| 2013 |
Tomkinson AE, Sallmyr A. Structure and function of the DNA ligases encoded by the mammalian LIG3 gene. Gene. 531: 150-7. PMID 24013086 DOI: 10.1016/j.gene.2013.08.061 |
0.813 |
|
| 2013 |
Hegde ML, Hegde PM, Bellot LJ, Mandal SM, Hazra TK, Li GM, Boldogh I, Tomkinson AE, Mitra S. Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E3090-9. PMID 23898192 DOI: 10.1073/Pnas.1304231110 |
0.697 |
|
| 2013 |
Tobin LA, Robert C, Rapoport AP, Gojo I, Baer MR, Tomkinson AE, Rassool FV. Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias. Oncogene. 32: 1784-93. PMID 22641215 DOI: 10.1038/onc.2012.203 |
0.597 |
|
| 2012 |
Della-Maria J, Hegde ML, McNeill DR, Matsumoto Y, Tsai MS, Ellenberger T, Wilson DM, Mitra S, Tomkinson AE. The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites. The Journal of Biological Chemistry. 287: 39233-44. PMID 22992732 DOI: 10.1074/Jbc.M112.369975 |
0.772 |
|
| 2012 |
Peng Z, Liao Z, Dziegielewska B, Matsumoto Y, Thomas S, Wan Y, Yang A, Tomkinson AE. Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair. The Journal of Biological Chemistry. 287: 36711-9. PMID 22952233 DOI: 10.1074/Jbc.M112.383570 |
0.664 |
|
| 2012 |
Howes TR, Tomkinson AE. DNA ligase I, the replicative DNA ligase. Sub-Cellular Biochemistry. 62: 327-41. PMID 22918593 DOI: 10.1007/978-94-007-4572-8_17 |
0.795 |
|
| 2012 |
Dey S, Maiti AK, Hegde ML, Hegde PM, Boldogh I, Sarkar PS, Abdel-Rahman SZ, Sarker AH, Hang B, Xie J, Tomkinson AE, Zhou M, Shen B, Wang G, Wu C, et al. Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2. Dna Repair. 11: 570-8. PMID 22497777 DOI: 10.1016/J.Dnarep.2012.03.005 |
0.589 |
|
| 2012 |
Goula AV, Pearson CE, Della Maria J, Trottier Y, Tomkinson AE, Wilson DM, Merienne K. The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision repair outcome at CAG/CTG repeats. Biochemistry. 51: 3919-32. PMID 22497302 DOI: 10.1021/Bi300410D |
0.519 |
|
| 2012 |
Gamper AM, Choi S, Matsumoto Y, Banerjee D, Tomkinson AE, Bakkenist CJ. ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis. The Journal of Biological Chemistry. 287: 12445-54. PMID 22362778 DOI: 10.1074/Jbc.M112.352310 |
0.746 |
|
| 2012 |
Tseng HM, Shum D, Bhinder B, Escobar S, Veomett NJ, Tomkinson AE, Gin DY, Djaballah H, Scheinberg DA. A high-throughput scintillation proximity-based assay for human DNA ligase IV. Assay and Drug Development Technologies. 10: 235-49. PMID 22192310 DOI: 10.1089/Adt.2011.0404 |
0.831 |
|
| 2012 |
Tobin LA, Robert C, Nagaria P, Chumsri S, Twaddell W, Ioffe OB, Greco GE, Brodie AH, Tomkinson AE, Rassool FV. Targeting abnormal DNA repair in therapy-resistant breast cancers. Molecular Cancer Research : McR. 10: 96-107. PMID 22112941 DOI: 10.1158/1541-7786.MCR-11-0255 |
0.537 |
|
| 2012 |
Grob P, Zhang TT, Hannah R, Yang H, Hefferin ML, Tomkinson AE, Nogales E. Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV. Dna Repair. 11: 74-81. PMID 22088982 DOI: 10.1016/J.Dnarep.2011.10.023 |
0.812 |
|
| 2011 |
Odell ID, Barbour JE, Murphy DL, Della-Maria JA, Sweasy JB, Tomkinson AE, Wallace SS, Pederson DS. Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. Molecular and Cellular Biology. 31: 4623-32. PMID 21930793 DOI: 10.1128/Mcb.05715-11 |
0.672 |
|
| 2011 |
Della-Maria J, Zhou Y, Tsai MS, Kuhnlein J, Carney JP, Paull TT, Tomkinson AE. Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. The Journal of Biological Chemistry. 286: 33845-53. PMID 21816818 DOI: 10.1074/Jbc.M111.274159 |
0.772 |
|
| 2011 |
Overmeer RM, Moser J, Volker M, Kool H, Tomkinson AE, van Zeeland AA, Mullenders LH, Fousteri M. Replication protein A safeguards genome integrity by controlling NER incision events. The Journal of Cell Biology. 192: 401-15. PMID 21282463 DOI: 10.1083/Jcb.201006011 |
0.654 |
|
| 2011 |
Chen X, Tomkinson AE. Yeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining. The Journal of Biological Chemistry. 286: 4931-40. PMID 21149442 DOI: 10.1074/jbc.M110.195024 |
0.669 |
|
| 2010 |
Rassool FV, Tomkinson AE. Targeting abnormal DNA double strand break repair in cancer. Cellular and Molecular Life Sciences : Cmls. 67: 3699-710. PMID 20697770 DOI: 10.1007/s00018-010-0493-5 |
0.456 |
|
| 2010 |
Cotner-Gohara E, Kim IK, Hammel M, Tainer JA, Tomkinson AE, Ellenberger T. Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states Biochemistry. 49: 6165-6176. PMID 20518483 DOI: 10.1021/Bi100503W |
0.757 |
|
| 2010 |
Berquist BR, Singh DK, Fan J, Kim D, Gillenwater E, Kulkarni A, Bohr VA, Ackerman EJ, Tomkinson AE, Wilson DM. Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population. Nucleic Acids Research. 38: 5023-35. PMID 20385586 DOI: 10.1093/Nar/Gkq193 |
0.66 |
|
| 2009 |
López Castel A, Tomkinson AE, Pearson CE. CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair. The Journal of Biological Chemistry. 284: 26631-45. PMID 19628465 DOI: 10.1074/Jbc.M109.034405 |
0.724 |
|
| 2009 |
Chen X, Ballin JD, Della-Maria J, Tsai MS, White EJ, Tomkinson AE, Wilson GM. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair. Dna Repair. 8: 961-8. PMID 19589734 DOI: 10.1016/j.dnarep.2009.06.002 |
0.796 |
|
| 2009 |
Song W, Pascal JM, Ellenberger T, Tomkinson AE. The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1. Dna Repair. 8: 912-9. PMID 19523882 DOI: 10.1016/J.Dnarep.2009.05.002 |
0.777 |
|
| 2009 |
Vijayakumar S, Dziegielewska B, Levin DS, Song W, Yin J, Yang A, Matsumoto Y, Bermudez VP, Hurwitz J, Tomkinson AE. Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair. Molecular and Cellular Biology. 29: 2042-52. PMID 19223468 DOI: 10.1128/Mcb.01732-08 |
0.77 |
|
| 2009 |
Tobin LA, Rapoport AP, Gojo I, Baer MR, Tomkinson AE, Rassool FV. DNA Ligase III Alpha and (Poly-ADP) Ribose Polymerase (PARP1) Are Therapeutic Targets in Imatinib-Resistant (IR) Chronic Myeloid Leukemia (CML). Blood. 114: 853-853. DOI: 10.1182/blood.v114.22.853.853 |
0.577 |
|
| 2008 |
Zhong S, Chen X, Zhu X, Dziegielewska B, Bachman KE, Ellenberger T, Ballin JD, Wilson GM, Tomkinson AE, MacKerell AD. Identification and Validation of Human DNA Ligase Inhibitors Using Computer-Aided Drug Design Journal of Medicinal Chemistry. 51: 4553-4562. PMID 18630893 DOI: 10.1021/Jm8001668 |
0.724 |
|
| 2008 |
Sallmyr A, Tomkinson AE, Rassool FV. Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks. Blood. 112: 1413-23. PMID 18524993 DOI: 10.1182/blood-2007-07-104257 |
0.754 |
|
| 2008 |
Ellenberger T, Tomkinson AE. Eukaryotic DNA ligases: structural and functional insights. Annual Review of Biochemistry. 77: 313-38. PMID 18518823 DOI: 10.1146/Annurev.Biochem.77.061306.123941 |
0.78 |
|
| 2008 |
Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD, Tomkinson AE. Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair Cancer Research. 68: 3169-3177. PMID 18451142 DOI: 10.1158/0008-5472.Can-07-6636 |
0.741 |
|
| 2008 |
Cotner-Gohara E, Kim IK, Tomkinson AE, Ellenberger T. Two DNA-binding and nick recognition modules in human DNA ligase III Journal of Biological Chemistry. 283: 10764-10772. PMID 18238776 DOI: 10.1074/Jbc.M708175200 |
0.727 |
|
| 2008 |
Sallmyr A, Tobin L, Tomkinson AE, Rassool FV. Inhibiting Alternative Non Homologus Endjoining (NHEJ) Pathways: Therapeutic Targets in Chronic Myeloid Leukemia (CML). Blood. 112: 1088-1088. DOI: 10.1182/blood.v112.11.1088.1088 |
0.684 |
|
| 2008 |
Ellenberger T, Tomkinson AE. Eukaryotic DNA ligases: Structural and functional insights Annual Review of Biochemistry. 77: 313-338. DOI: 10.1146/annurev.biochem.77.061306.123941 |
0.651 |
|
| 2007 |
Zhang Y, Hefferin ML, Chen L, Shim EY, Tseng HM, Kwon Y, Sung P, Lee SE, Tomkinson AE. Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nature Structural & Molecular Biology. 14: 639-46. PMID 17589524 DOI: 10.1038/Nsmb1261 |
0.883 |
|
| 2007 |
Song W, Levin DS, Varkey J, Post S, Bermudez VP, Hurwitz J, Tomkinson AE. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. The Journal of Biological Chemistry. 282: 22721-30. PMID 17561505 DOI: 10.1074/Jbc.M703774200 |
0.818 |
|
| 2007 |
Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE. The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase Nucleic Acids Research. 35: 1624-1637. PMID 17308348 DOI: 10.1093/Nar/Gkm006 |
0.644 |
|
| 2006 |
Pascal JM, Tsodikov OV, Hura GL, Song W, Cotner EA, Classen S, Tomkinson AE, Tainer JA, Ellenberger T. A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Molecular Cell. 24: 279-91. PMID 17052461 DOI: 10.1016/J.Molcel.2006.08.015 |
0.767 |
|
| 2006 |
Dong Z, Tomkinson AE. ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. Nucleic Acids Research. 34: 5721-279. PMID 17040896 DOI: 10.1093/nar/gkl705 |
0.689 |
|
| 2006 |
Das A, Wiederhold L, Leppard JB, Kedar P, Prasad R, Wang H, Boldogh I, Karimi-Busheri F, Weinfeld M, Tomkinson AE, Wilson SH, Mitra S, Hazra TK. NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. Dna Repair. 5: 1439-48. PMID 16982218 DOI: 10.1016/J.Dnarep.2006.07.003 |
0.712 |
|
| 2006 |
Chen X, Pascal J, Vijayakumar S, Wilson GM, Ellenberger T, Tomkinson AE. Human DNA Ligases I, III, and IV-Purification and New Specific Assays for These Enzymes Methods in Enzymology. 409: 39-52. PMID 16793394 DOI: 10.1016/S0076-6879(05)09003-8 |
0.8 |
|
| 2006 |
Tomkinson AE, Vijayakumar S, Pascal JM, Ellenberger T. DNA ligases: structure, reaction mechanism, and function. Chemical Reviews. 106: 687-99. PMID 16464020 DOI: 10.1021/Cr040498D |
0.547 |
|
| 2005 |
Zhang Y, Yuan F, Presnell SR, Tian K, Gao Y, Tomkinson AE, Gu L, Li GM. Reconstitution of 5'-directed human mismatch repair in a purified system. Cell. 122: 693-705. PMID 16143102 DOI: 10.1016/J.Cell.2005.06.027 |
0.439 |
|
| 2005 |
Subramanian J, Vijayakumar S, Tomkinson AE, Arnheim N. Genetic instability induced by overexpression of DNA ligase I in budding yeast. Genetics. 171: 427-41. PMID 15965249 DOI: 10.1534/Genetics.105.042861 |
0.676 |
|
| 2005 |
Goetz JD, Motycka TA, Han M, Jasin M, Tomkinson AE. Reduced repair of DNA double-strand breaks by homologous recombination in a DNA ligase I-deficient human cell line. Dna Repair. 4: 649-54. PMID 15907772 DOI: 10.1016/J.Dnarep.2005.02.004 |
0.883 |
|
| 2005 |
Hefferin ML, Tomkinson AE. Mechanism of DNA double-strand break repair by non-homologous end joining. Dna Repair. 4: 639-48. PMID 15907771 DOI: 10.1016/j.dnarep.2004.12.005 |
0.735 |
|
| 2005 |
Okano S, Lan L, Tomkinson AE, Yasui A. Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells. Nucleic Acids Research. 33: 422-9. PMID 15653642 DOI: 10.1093/nar/gki190 |
0.672 |
|
| 2005 |
Chen L, Trujillo KM, Van Komen S, Roh DH, Krejci L, Lewis LK, Resnick MA, Sung P, Tomkinson AE. Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. The Journal of Biological Chemistry. 280: 2620-7. PMID 15546877 DOI: 10.1074/Jbc.M410192200 |
0.724 |
|
| 2004 |
Pascal JM, O'Brien PJ, Tomkinson AE, Ellenberger T. Human DNA ligase I completely encircles and partially unwinds nicked DNA. Nature. 432: 473-8. PMID 15565146 DOI: 10.1038/Nature03082 |
0.815 |
|
| 2004 |
Levin DS, Vijayakumar S, Liu X, Bermudez VP, Hurwitz J, Tomkinson AE. A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining. The Journal of Biological Chemistry. 279: 55196-201. PMID 15502161 DOI: 10.1074/Jbc.M409250200 |
0.801 |
|
| 2004 |
Della M, Palmbos PL, Tseng HM, Tonkin LM, Daley JM, Topper LM, Pitcher RS, Tomkinson AE, Wilson TE, Doherty AJ. Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science (New York, N.Y.). 306: 683-5. PMID 15499016 DOI: 10.1126/science.1099824 |
0.859 |
|
| 2004 |
Tseng HM, Tomkinson AE. Processing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1. The Journal of Biological Chemistry. 279: 47580-8. PMID 15342630 DOI: 10.1074/jbc.M404492200 |
0.9 |
|
| 2004 |
Wiederhold L, Leppard JB, Kedar P, Karimi-Busheri F, Rasouli-Nia A, Weinfeld M, Tomkinson AE, Izumi T, Prasad R, Wilson SH, Mitra S, Hazra TK. AP endonuclease-independent DNA base excision repair in human cells. Molecular Cell. 15: 209-20. PMID 15260972 DOI: 10.1016/J.Molcel.2004.06.003 |
0.746 |
|
| 2004 |
Lei X, Zhu Y, Tomkinson A, Sun L. Measurement of DNA mismatch repair activity in live cells. Nucleic Acids Research. 32: e100. PMID 15249596 DOI: 10.1093/Nar/Gnh098 |
0.463 |
|
| 2004 |
Fan J, Otterlei M, Wong HK, Tomkinson AE, Wilson DM. XRCC1 co-localizes and physically interacts with PCNA. Nucleic Acids Research. 32: 2193-201. PMID 15107487 DOI: 10.1093/Nar/Gkh556 |
0.551 |
|
| 2004 |
Motycka TA, Bessho T, Post SM, Sung P, Tomkinson AE. Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52. The Journal of Biological Chemistry. 279: 13634-9. PMID 14734547 DOI: 10.1074/Jbc.M313779200 |
0.872 |
|
| 2003 |
Trujillo KM, Roh DH, Chen L, Van Komen S, Tomkinson A, Sung P. Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends. The Journal of Biological Chemistry. 278: 48957-48964. PMID 14522986 DOI: 10.1074/Jbc.M309877200 |
0.818 |
|
| 2003 |
Krejci L, Chen L, Van Komen S, Sung P, Tomkinson A. Mending the break: two DNA double-strand break repair machines in eukaryotes. Progress in Nucleic Acid Research and Molecular Biology. 74: 159-201. PMID 14510076 DOI: 10.1016/S0079-6603(03)01013-4 |
0.787 |
|
| 2003 |
Post SM, Tomkinson AE, Lee EY. The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. Nucleic Acids Research. 31: 5568-75. PMID 14500819 DOI: 10.1093/Nar/Gkg765 |
0.817 |
|
| 2003 |
Leppard JB, Dong Z, Mackey ZB, Tomkinson AE. Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair. Molecular and Cellular Biology. 23: 5919-27. PMID 12897160 DOI: 10.1128/Mcb.23.16.5919-5927.2003 |
0.905 |
|
| 2002 |
Tseng HM, Tomkinson AE. A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining. The Journal of Biological Chemistry. 277: 45630-7. PMID 12235149 DOI: 10.1074/Jbc.M206861200 |
0.9 |
|
| 2001 |
Chen L, Trujillo K, Ramos W, Sung P, Tomkinson AE. Promotion of Dnl4-Catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes Molecular Cell. 8: 1105-1115. PMID 11741545 DOI: 10.1016/S1097-2765(01)00388-4 |
0.816 |
|
| 2001 |
Tomkinson AE, Chen L, Dong Z, Leppard JB, Levin DS, Mackey ZB, Motycka TA. Completion of base excision repair by mammalian DNA ligases. Progress in Nucleic Acid Research and Molecular Biology. 68: 151-64. PMID 11554294 DOI: 10.1016/S0079-6603(01)68097-8 |
0.853 |
|
| 2000 |
Levin DS, McKenna AE, Motycka TA, Matsumoto Y, Tomkinson AE. Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair. Current Biology : Cb. 10: 919-22. PMID 10959839 DOI: 10.1016/S0960-9822(00)00619-9 |
0.87 |
|
| 2000 |
Chen L, Trujillo K, Sung P, Tomkinson AE. Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase Journal of Biological Chemistry. 275: 26196-26205. PMID 10854421 DOI: 10.1074/Jbc.M000491200 |
0.841 |
|
| 2000 |
Izumi T, Hazra TK, Boldogh I, Tomkinson AE, Park MS, Ikeda S, Mitra S. Requirement for human AP endonuclease 1 for repair of 3′-blocking damage at DNA single-strand breaks induced by reactive oxygen species Carcinogenesis. 21: 1329-1334. DOI: 10.1093/Carcin/21.7.1329 |
0.715 |
|
| 1999 |
Dasika GK, Lin SC, Zhao S, Sung P, Tomkinson A, Lee EY. DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene. 18: 7883-99. PMID 10630641 DOI: 10.1038/Sj.Onc.1203283 |
0.687 |
|
| 1999 |
Matsumoto Y, Kim K, Hurwitz J, Gary R, Levin DS, Tomkinson AE, Park MS. Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins Journal of Biological Chemistry. 274: 33703-33708. PMID 10559261 DOI: 10.1074/Jbc.274.47.33703 |
0.691 |
|
| 1999 |
Mackey ZB, Niedergang C, Murcia JM, Leppard J, Au K, Chen J, de Murcia G, Tomkinson AE. DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III. The Journal of Biological Chemistry. 274: 21679-87. PMID 10419478 DOI: 10.1074/Jbc.274.31.21679 |
0.893 |
|
| 1999 |
Rodriguez K, Talamantez J, Huang W, Reed SH, Wang Z, Chen L, Feaver WJ, Friedberg EC, Tomkinson AE. Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein. The Journal of Biological Chemistry. 273: 34180-9. PMID 9852079 DOI: 10.1074/Jbc.273.51.34180 |
0.589 |
|
| 1999 |
Ramos W, Liu G, Giroux CN, Tomkinson AE. Biochemical and genetic characterization of the DNA ligase encoded by Saccharomyces cerevisiae open reading frame YOR005c, a homolog of mammalian DNA ligase IV. Nucleic Acids Research. 26: 5676-83. PMID 9837999 DOI: 10.1093/Nar/26.24.5676 |
0.671 |
|
| 1998 |
Huang W, Feaver WJ, Tomkinson AE, Friedberg EC. The N-degron protein degradation strategy for investigating the function of essential genes: requirement for replication protein A and proliferating cell nuclear antigen proteins for nucleotide excision repair in yeast extracts. Mutation Research. 408: 183-94. PMID 9806417 DOI: 10.1016/S0921-8777(98)00031-7 |
0.582 |
|
| 1998 |
Karimi-Busheri F, Lee J, Tomkinson AE, Weinfeld M. Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes. Nucleic Acids Research. 26: 4395-400. PMID 9742240 DOI: 10.1093/Nar/26.19.4395 |
0.733 |
|
| 1998 |
Srivastava DK, Berg BJ, Prasad R, Molina JT, Beard WA, Tomkinson AE, Wilson SH. Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. The Journal of Biological Chemistry. 273: 21203-9. PMID 9694877 DOI: 10.1074/Jbc.273.33.21203 |
0.757 |
|
| 1998 |
Dimitriadis EK, Prasad R, Vaske MK, Chen L, Tomkinson AE, Lewis MS, Wilson SH. Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta. The Journal of Biological Chemistry. 273: 20540-50. PMID 9685411 DOI: 10.1074/Jbc.273.32.20540 |
0.631 |
|
| 1998 |
Montecucco A, Rossi R, Levin DS, Gary R, Park MS, Motycka TA, Ciarrocchi G, Villa A, Biamonti G, Tomkinson AE. DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories. The Embo Journal. 17: 3786-95. PMID 9649448 DOI: 10.1093/Emboj/17.13.3786 |
0.863 |
|
| 1998 |
Tomkinson AE, Mackey ZB. Structure and function of mammalian DNA ligases. Mutation Research. 407: 1-9. PMID 9539976 DOI: 10.1016/S0921-8777(97)00050-5 |
0.913 |
|
| 1997 |
Kamel D, Mackey ZB, Sjöblom T, Walter CA, McCarrey JR, Uitto L, Palosaari H, Lähdetie J, Tomkinson AE, Syväoja JE. Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice. Biology of Reproduction. 57: 1367-74. PMID 9408242 DOI: 10.1095/Biolreprod57.6.1367 |
0.884 |
|
| 1997 |
Levin DS, Bai W, Yao N, O'Donnell M, Tomkinson AE. An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining. Proceedings of the National Academy of Sciences of the United States of America. 94: 12863-8. PMID 9371766 DOI: 10.1073/pnas.94.24.12863 |
0.824 |
|
| 1997 |
Tomkinson AE, Levin DS. Mammalian DNA ligases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 893-901. PMID 9363683 DOI: 10.1002/Bies.950191009 |
0.854 |
|
| 1997 |
Du Q, Tomkinson AE, Gardner PD. Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. A possible role for the DNA-binding protein Puralpha. The Journal of Biological Chemistry. 272: 14990-5. PMID 9169473 DOI: 10.1074/Jbc.272.23.14990 |
0.473 |
|
| 1997 |
Ramos W, Tappe N, Talamantez J, Friedberg EC, Tomkinson AE. Two distinct DNA ligase activities in mitotic extracts of the yeast Saccharomyces cerevisiae. Nucleic Acids Research. 25: 1485-92. PMID 9092653 DOI: 10.1093/Nar/25.8.1485 |
0.821 |
|
| 1997 |
Mackey ZB, Ramos W, Levin DS, Walter CA, McCarrey JR, Tomkinson AE. An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Molecular and Cellular Biology. 17: 989-98. PMID 9001252 DOI: 10.1128/Mcb.17.2.989 |
0.876 |
|
| 1996 |
Tang CM, Tomkinson AE, Lane WS, Wold MS, Seto E. Replication protein A is a component of a complex that binds the human metallothionein IIA gene transcription start site. The Journal of Biological Chemistry. 271: 21637-44. PMID 8702952 DOI: 10.1074/Jbc.271.35.21637 |
0.39 |
|
| 1996 |
Rodriguez K, Wang Z, Friedberg EC, Tomkinson AE. Identification of functional domains within the RAD1·RAD10 repair and recombination endonuclease of Saccharomyces cerevisiae Journal of Biological Chemistry. 271: 20551-20558. PMID 8702799 DOI: 10.1074/Jbc.271.34.20551 |
0.706 |
|
| 1996 |
Prasad R, Singhal RK, Srivastava DK, Molina JT, Tomkinson AE, Wilson SH. Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis. The Journal of Biological Chemistry. 271: 16000-7. PMID 8663274 DOI: 10.1074/Jbc.271.27.16000 |
0.575 |
|
| 1995 |
Friedberg EC, Bardwell AJ, Bardwell L, Feaver WJ, Kornberg RD, Svejstrup JQ, Tomkinson AE, Wang Z. Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 347: 63-68. PMID 7746856 DOI: 10.1098/Rstb.1995.0010 |
0.397 |
|
| 1995 |
Husain I, Tomkinson AE, Burkhart WA, Moyer MB, Ramos W, Mackey ZB, Besterman JM, Chen J. Purification and characterization of DNA ligase III from bovine testes. Homology with DNA ligase II and vaccinia DNA ligase. The Journal of Biological Chemistry. 270: 9683-90. PMID 7721901 DOI: 10.1074/Jbc.270.16.9683 |
0.889 |
|
| 1995 |
Chen J, Tomkinson AE, Ramos W, Mackey ZB, Danehower S, Walter CA, Schultz RA, Besterman JM, Husain I. Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination. Molecular and Cellular Biology. 15: 5412-22. PMID 7565692 DOI: 10.1128/Mcb.15.10.5412 |
0.891 |
|
| 1995 |
Davies AA, Friedberg EC, Tomkinson AE, Wood RD, West SC. Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination. The Journal of Biological Chemistry. 270: 24638-41. PMID 7559571 DOI: 10.1074/Jbc.270.42.24638 |
0.762 |
|
| 1994 |
Tomkinson AE, Bardwell AJ, Tappe N, Ramos W, Friedberg EC. Purification of Rad1 protein from Saccharomyces cerevisiae and further characterization of the Rad1/Rad10 endonuclease complex. Biochemistry. 33: 5305-11. PMID 8172904 DOI: 10.1021/Bi00183A038 |
0.718 |
|
| 1994 |
Bardwell AJ, Bardwell L, Wang Z, Siede W, Reagan MS, Tomkinson AE, Friedberg AS, Pittenger C, Feaver WJ, Svejstrup J, Kornberg RD, Friedberg EC. Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes Annals of the New York Academy of Sciences. 726: 281-291. PMID 8092684 DOI: 10.1111/J.1749-6632.1994.Tb52829.X |
0.754 |
|
| 1994 |
Bardwell AJ, Bardwell L, Tomkinson AE, Friedberg EC. Specific cleavage of model recombination and repair intermediates by the yeast Rad1-Rad10 DNA endonuclease Science. 265: 2082-2085. PMID 8091230 DOI: 10.1126/Science.8091230 |
0.755 |
|
| 1994 |
Wang YC, Burkhart WA, Mackey ZB, Moyer MB, Ramos W, Husain I, Chen J, Besterman JM, Tomkinson AE. Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation. The Journal of Biological Chemistry. 269: 31923-8. PMID 7989368 |
0.887 |
|
| 1993 |
Tomkinson AE, Starr R, Schultz RA. DNA ligase III is the major high molecular weight DNA joining activity in SV40-transformed human fibroblasts: Normal levels of DNA ligase III activity in bloom syndrome cells Nucleic Acids Research. 21: 5425-5430. PMID 8265359 DOI: 10.1093/Nar/21.23.5425 |
0.765 |
|
| 1992 |
Barnes DE, Tomkinson AE, Lehmann AR, Webster ADB, Lindahl T. Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents Cell. 69: 495-503. PMID 1581963 DOI: 10.1016/0092-8674(92)90450-Q |
0.781 |
|
| 1992 |
Tomkinson AE, Tappe NJ, Friedberg EC. DNA ligase I from Saccharomyces cerevisiae: physical and biochemical characterization of the CDC9 gene product. Biochemistry. 31: 11762-71. PMID 1445910 DOI: 10.1021/Bi00162A013 |
0.801 |
|
| 1991 |
Tomkinson AE, Totty NF, Ginsburg M, Lindahl T. Location of the active site for enzyme-adenylate formation in DNA ligases. Proceedings of the National Academy of Sciences of the United States of America. 88: 400-4. PMID 1988940 DOI: 10.1073/pnas.88.2.400 |
0.598 |
|
| 1990 |
Tomkinson AE, Bonk RT, Kim J, Bartfeld N, Linn S. Mammalian mitochondrial endonuclease activities specific for ultraviolet-irradiated DNA. Nucleic Acids Research. 18: 929-35. PMID 2315045 DOI: 10.1093/Nar/18.4.929 |
0.406 |
|
| 1990 |
Lasko DD, Tomkinson AE, Lindahl T. Eukaryotic DNA ligases. Mutation Research. 236: 277-87. PMID 2204827 DOI: 10.1016/0921-8777(90)90011-S |
0.714 |
|
| 1990 |
Barnes DE, Johnston LH, Kodama KI, Tomkinson AE, Lasko DD, Lindahl T. Human DNA ligase I cDNA: Cloning and functional expression in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 87: 6679-6683. PMID 2204063 DOI: 10.1073/pnas.87.17.6679 |
0.637 |
|
| 1986 |
Tomkinson AE, Linn S. Purification and properties of a single strand-specific endonuclease from mouse cell mitochondria. Nucleic Acids Research. 14: 9579-93. PMID 3027656 DOI: 10.1093/Nar/14.24.9579 |
0.599 |
|
| 1981 |
Hickson ID, Gordon RL, Tomkinson AE, Emmerson PT. A temperature sensitive RecA protein of Escherichia coli Mgg Molecular &Amp; General Genetics. 184: 68-72. PMID 6460915 DOI: 10.1007/BF00271197 |
0.494 |
|
| Show low-probability matches. |