Eckhard R. Podack - Publications

Affiliations: 
Microbiology and Immunology (Medicine) University of Miami, Coral Gables, FL 
Area:
Immunology, Oncology, Cell Biology

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Frasca D, Diaz A, Romero M, Vazquez T, Strbo N, Romero L, McCormack RM, Podack ER, Blomberg BB. Impaired B Cell Function in Mice Lacking Perforin-2. Frontiers in Immunology. 11: 328. PMID 32180773 DOI: 10.3389/Fimmu.2020.00328  0.342
2020 McCormack R, Hunte R, Podack ER, Plano GV, Shembade N. An Essential Role for Perforin-2 in Type I IFN Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 32161097 DOI: 10.4049/Jimmunol.1901013  0.306
2017 Madireddi S, Eun SY, Mehta AK, Birta A, Zajonc DM, Niki T, Hirashima M, Podack ER, Schreiber TH, Croft M. Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. Journal of Immunology (Baltimore, Md. : 1950). PMID 28877989 DOI: 10.4049/Jimmunol.1700575  0.734
2017 Garcia-Soto AE, Schreiber T, Strbo N, Ganjei-Azar P, Miao F, Koru-Sengul T, Simpkins F, Nieves-Neira W, Lucci J, Podack ER. Cancer-testis antigen expression is shared between epithelial ovarian cancer tumors. Gynecologic Oncology. PMID 28392126 DOI: 10.1016/J.Ygyno.2017.03.512  0.663
2017 Wolf D, Barreras H, Bader CS, Copsel S, Lightbourn CO, Pfeiffer BJ, Altman NH, Podack ER, Komanduri KV, Levy RB. Marked in vivo Donor Treg Expansion via IL-2 and TL1A-Ig Stimulation Ameliorates GVHD but Preserves GVL in Recipients Post-HSCT. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 28219835 DOI: 10.1016/J.Bbmt.2017.02.013  0.359
2017 Wolf D, Barreras H, Bader C, Copsel S, Lightbourn C, Pfeiffer B, Podack E, Komanduri K, Levy R. Marked in vivo Donor Treg expansion via targeting of the IL-2/CD25 and TL1A/TNFRSF25 pathways ameliorates GVHD and preserves GVL Cytotherapy. 19: S11-S12. DOI: 10.1016/J.Jcyt.2017.02.017  0.371
2016 Podack ER, Munson GP. Killing of Microbes and Cancer by the Immune System with Three Mammalian Pore-Forming Killer Proteins. Frontiers in Immunology. 7: 464. PMID 27857713 DOI: 10.3389/Fimmu.2016.00464  0.38
2016 Alcaide ML, Strbo N, Romero L, Jones DL, Rodriguez VJ, Arheart K, Martinez O, Bolivar H, Podack ER, Fischl MA. Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study. Plos One. 11: e0153045. PMID 27078021 DOI: 10.1371/Journal.Pone.0153045  0.33
2016 McCormack R, Bahnan W, Shrestha N, Boucher J, Barreto M, Barrera CM, Dauer EA, Freitag NE, Khan WN, Podack ER, Schesser K. Perforin-2 protects host cells and mice by restricting the vacuole to cytosol transitioning of a bacterial pathogen. Infection and Immunity. PMID 26831467 DOI: 10.1128/Iai.01434-15  0.325
2016 Wolf D, Barreras H, Bader CS, Razdan S, Lightbourn CO, Pfeiffer BJ, Elliot SJ, Podack ER, Komanduri KV, Levy RB. Marked In Vivo Expansion of Donor T Regulatory Cells Via Targeting of the IL-2/CD25 and TL1A/TNFRSF25 Pathways Elicits Gender Differences and Ameliorates Gvhd Biology of Blood and Marrow Transplantation. 22: S418. DOI: 10.1016/J.Bbmt.2015.11.956  0.431
2015 Strbo N, Alcaide ML, Romero L, Bolivar H, Jones D, Podack ER, Fischl MA. Loss of Intra-Epithelial Endocervical Gamma Delta (GD) 1 T Cells in HIV-Infected Women. American Journal of Reproductive Immunology (New York, N.Y. : 1989). PMID 26666220 DOI: 10.1111/Aji.12458  0.39
2015 McCormack RM, Lyapichev K, Olsson ML, Podack ER, Munson GP. Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2. Elife. 4. PMID 26418746 DOI: 10.7554/Elife.06505  0.345
2015 McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, ... ... Podack ER, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. Elife. 4. PMID 26402460 DOI: 10.7554/Elife.06508  0.622
2015 McCormack R, Podack ER. Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution. Journal of Leukocyte Biology. 98: 761-8. PMID 26307549 DOI: 10.1189/Jlb.4Mr1114-523Rr  0.304
2015 Dranitsaris G, Cohen RB, Acton G, Keltner L, Price M, Amir E, Podack ER, Schreiber TH. Statistical Considerations in Clinical Trial Design of Immunotherapeutic Cancer Agents. Journal of Immunotherapy (Hagerstown, Md. : 1997). 38: 259-66. PMID 26261889 DOI: 10.1097/Cji.0000000000000089  0.657
2015 Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, ... Podack ER, et al. Immunological mechanisms of the antitumor effects of supplemental oxygenation. Science Translational Medicine. 7: 277ra30. PMID 25739764 DOI: 10.1126/Scitranslmed.Aaa1260  0.711
2015 Shinoda K, Sun X, Oyamada A, Yamada H, Muta H, Podack ER, Kira J, Yoshikai Y. CD30 ligand is a new therapeutic target for central nervous system autoimmunity. Journal of Autoimmunity. 57: 14-23. PMID 25533628 DOI: 10.1016/J.Jaut.2014.11.005  0.464
2015 McCormack RM, Armas LRd, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, ... ... Podack ER, et al. Author response: Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria Elife. DOI: 10.7554/Elife.06508.037  0.602
2015 McCormack RM, Lyapichev K, Olsson ML, Podack ER, Munson GP. Author response: Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2 Elife. DOI: 10.7554/Elife.06505.024  0.312
2015 Wolf D, Barreras H, Bader CS, Lightbourn CO, Pfeiffer BJ, Podack ER, Komanduri KV, Levy RB. Targeting the IL-2/CD25 and TL1A/TNFRSF25 Pathways: A New Approach to Markedly Expand Donor Tregs in Multiple Compartments Leads to in Situ Immune Regulation Blood. 126: 4281-4281. DOI: 10.1182/Blood.V126.23.4281.4281  0.453
2015 Garcia-Soto AE, Koru-Sengul T, Miao F, Schreiber T, Nieves-Neira W, Podack E. Abstract A24: Cancer-testis antigen expression is shared among gynecological tumors Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-A24  0.665
2015 Wolf D, Barreras H, Komanduri KV, Podack ER, Levy RB. In Situ Manipulation of Tregs Via Combined IL-2 and TNFRSF25 Signaling Pre- and Post-Transplant: A Novel Approach to Regulate GVHD By Marked Expansion of CD4+Foxp3+ T Cells Biology of Blood and Marrow Transplantation. 21: S320. DOI: 10.1016/J.Bbmt.2014.11.689  0.415
2014 Podack ER. The molecular mechanism of lymphocyte-mediated tumor cell lysis. Immunology Today. 6: 21-7. PMID 25291203 DOI: 10.1016/0167-5699(85)90164-1  0.432
2014 Selinger C, Strbo N, Gonzalez L, Aicher L, Weiss JM, Law GL, Palermo RE, Vaccari M, Franchini G, Podack ER, Katze MG. Multiple low-dose challenges in a rhesus macaque AIDS vaccine trial result in an evolving host response that affects protective outcome. Clinical and Vaccine Immunology : Cvi. 21: 1650-60. PMID 25274805 DOI: 10.1128/Cvi.00455-14  0.613
2014 Hatfield SM, Kjaergaard J, Lukashev D, Belikoff B, Schreiber TH, Sethumadhavan S, Abbott R, Philbrook P, Thayer M, Shujia D, Rodig S, Kutok JL, Ren J, Ohta A, Podack ER, et al. Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection. Journal of Molecular Medicine (Berlin, Germany). 92: 1283-92. PMID 25120128 DOI: 10.1007/S00109-014-1189-3  0.681
2014 Newman RG, Dee MJ, Malek TR, Podack ER, Levy RB. Heat shock protein vaccination and directed IL-2 therapy amplify tumor immunity rapidly following bone marrow transplantation in mice. Blood. 123: 3045-55. PMID 24687086 DOI: 10.1182/Blood-2013-08-520775  0.486
2014 Schreiber TH, Schilling N, Deyev V, Podack ER. Abstract 5029: Comparative combination cancer immunotherapy with vaccination, checkpoint inhibition and TNFRSF stimulation Cancer Research. 74: 5029-5029. DOI: 10.1158/1538-7445.Am2014-5029  0.745
2013 Zhang Y, Morgan R, Podack ER, Rosenblatt J. B cell regulation of anti-tumor immune response. Immunologic Research. 57: 115-24. PMID 24293009 DOI: 10.1007/S12026-013-8472-1  0.456
2013 McCormack R, de Armas L, Shiratsuchi M, Podack ER. Killing machines: three pore-forming proteins of the immune system. Immunologic Research. 57: 268-78. PMID 24293008 DOI: 10.1007/S12026-013-8469-9  0.326
2013 Newman RG, Ross DB, Barreras H, Herretes S, Podack ER, Komanduri KV, Perez VL, Levy RB. The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success. Immunologic Research. 57: 125-39. PMID 24272856 DOI: 10.1007/S12026-013-8450-7  0.413
2013 Strbo N, Garcia-Soto A, Schreiber TH, Podack ER. Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases. Immunologic Research. 57: 311-25. PMID 24254084 DOI: 10.1007/S12026-013-8468-X  0.705
2013 Gonzalez L, Strbo N, Podack ER. Humanized mice: novel model for studying mechanisms of human immune-based therapies. Immunologic Research. 57: 326-34. PMID 24248605 DOI: 10.1007/S12026-013-8471-2  0.624
2013 Schreiber TH, Podack ER. Immunobiology of TNFSF15 and TNFRSF25. Immunologic Research. 57: 3-11. PMID 24242819 DOI: 10.1007/S12026-013-8465-0  0.732
2013 Podack ER. Immunology and microbiology in Miami. Immunologic Research. 57: 1-2. PMID 24242762 DOI: 10.1007/S12026-013-8470-3  0.303
2013 Muta H, Podack ER. CD30: from basic research to cancer therapy. Immunologic Research. 57: 151-8. PMID 24233555 DOI: 10.1007/S12026-013-8464-1  0.401
2013 Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack ER, Yoshikai Y. CD30 is required for activation of a unique subset of interleukin-17A-producing γδ T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection. Infection and Immunity. 81: 3923-34. PMID 23918785 DOI: 10.1128/Iai.00887-13  0.456
2013 Fields KA, McCormack R, de Armas LR, Podack ER. Perforin-2 restricts growth of Chlamydia trachomatis in macrophages. Infection and Immunity. 81: 3045-54. PMID 23753625 DOI: 10.1128/Iai.00497-13  0.337
2013 Sun X, Shibata K, Yamada H, Guo Y, Muta H, Podack ER, Yoshikai Y. CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice. Mucosal Immunology. 6: 1191-201. PMID 23549449 DOI: 10.1038/Mi.2013.18  0.41
2013 Strbo N, Vaccari M, Pahwa S, Kolber MA, Doster MN, Fisher E, Gonzalez L, Stablein D, Franchini G, Podack ER. Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virus. Journal of Immunology (Baltimore, Md. : 1950). 190: 2495-9. PMID 23401588 DOI: 10.4049/Jimmunol.1202655  0.61
2013 Khan SQ, Tsai MS, Schreiber TH, Wolf D, Deyev VV, Podack ER. Cloning, expression, and functional characterization of TL1A-Ig. Journal of Immunology (Baltimore, Md. : 1950). 190: 1540-50. PMID 23319737 DOI: 10.4049/Jimmunol.1201908  0.814
2013 McCormack R, de Armas LR, Shiratsuchi M, Ramos JE, Podack ER. Inhibition of intracellular bacterial replication in fibroblasts is dependent on the perforin-like protein (perforin-2) encoded by macrophage-expressed gene 1. Journal of Innate Immunity. 5: 185-94. PMID 23257510 DOI: 10.1159/000345249  0.317
2013 Zhang Y, Eliav Y, Shin SU, Schreiber TH, Podack ER, Tadmor T, Rosenblatt JD. B lymphocyte inhibition of anti-tumor response depends on expansion of Treg but is independent of B-cell IL-10 secretion. Cancer Immunology, Immunotherapy : Cii. 62: 87-99. PMID 22772949 DOI: 10.1007/S00262-012-1313-6  0.724
2013 Raez LE, Walker GR, Baldie P, Fisher E, Gomez JE, Tolba K, Santos ES, Podack ER. CD8 T cell response in a phase I study of therapeutic vaccination of advanced NSCLC with allogeneic tumor cells secreting endoplasmic reticulum-chaperone gp96-Ig-peptide complexes Advances in Lung Cancer. 2: 9-18. DOI: 10.4236/ALC.2013.21002  0.358
2013 Schreiber TH, Gonzalez L, Wolf D, Bodero M, Podack ER. Abstract A38: T cell costimulation by TNFRSF4, TNFRSF18, and TNFRSF25 in the context of vaccination. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-A38  0.808
2013 Newman RG, Podack ER, Levy RB. Abstract A32: Combining early heat shock protein vaccination with directed IL-2 leads to effective and persistent antitumor immunity in recipients of experimental autologous hematopoietic cell transplantation. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-A32  0.47
2012 Schreiber TH, Wolf D, Bodero M, Gonzalez L, Podack ER. T cell costimulation by TNFR superfamily (TNFRSF)4 and TNFRSF25 in the context of vaccination. Journal of Immunology (Baltimore, Md. : 1950). 189: 3311-8. PMID 22956587 DOI: 10.4049/Jimmunol.1200597  0.803
2012 Schreiber TH, Wolf D, Bodero M, Podack E. Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination. Oncoimmunology. 1: 642-648. PMID 22934256 DOI: 10.4161/Onci.20298  0.75
2012 Wolf D, Schreiber TH, Tryphonopoulos P, Li S, Tzakis AG, Ruiz P, Podack ER. Tregs expanded in vivo by TNFRSF25 agonists promote cardiac allograft survival. Transplantation. 94: 569-74. PMID 22902792 DOI: 10.1097/Tp.0B013E318264D3Ef  0.695
2012 J Reddy PB, Schreiber TH, Rajasagi NK, Suryawanshi A, Mulik S, Veiga-Parga T, Niki T, Hirashima M, Podack ER, Rouse BT. TNFRSF25 agonistic antibody and galectin-9 combination therapy controls herpes simplex virus-induced immunoinflammatory lesions. Journal of Virology. 86: 10606-20. PMID 22811539 DOI: 10.1128/Jvi.01391-12  0.721
2012 Cheng G, Yuan X, Tsai MS, Podack ER, Yu A, Malek TR. IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 1780-91. PMID 22786769 DOI: 10.4049/Jimmunol.1103768  0.671
2012 Somada S, Muta H, Nakamura K, Sun X, Honda K, Ihara E, Akiho H, Takayanagi R, Yoshikai Y, Podack ER, Tani K. CD30 ligand/CD30 interaction is involved in pathogenesis of inflammatory bowel disease. Digestive Diseases and Sciences. 57: 2031-7. PMID 22451116 DOI: 10.1007/S10620-012-2129-0  0.409
2011 Fuchiwaki T, Sun X, Fujimura K, Yamada H, Shibata K, Muta H, Podack ER, Kawauchi H, Yoshikai Y. The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice. European Journal of Immunology. 41: 2947-54. PMID 21739429 DOI: 10.1002/Eji.201141423  0.423
2011 Deutsch YE, Tadmor T, Podack ER, Rosenblatt JD. CD30: an important new target in hematologic malignancies. Leukemia & Lymphoma. 52: 1641-54. PMID 21619423 DOI: 10.3109/10428194.2011.574761  0.428
2011 Holt GE, Podack ER, Raez LE. Immunotherapy as a strategy for the treatment of non-small-cell lung cancer. Therapy (London, England : 2004). 8: 43-54. PMID 21359153 DOI: 10.2217/Thy.10.84  0.352
2011 Strbo N, Vaccari M, Pahwa S, Kolber MA, Fisher E, Gonzalez L, Doster MN, Hryniewicz A, Felber BK, Pavlakis GN, Franchini G, Podack ER. Gp96 SIV Ig immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa. Vaccine. 29: 2619-25. PMID 21277409 DOI: 10.1016/J.Vaccine.2011.01.044  0.69
2011 Tadmor T, Zhang Y, Cho HM, Podack ER, Rosenblatt JD. The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model. Cancer Immunology, Immunotherapy : Cii. 60: 609-19. PMID 21253724 DOI: 10.1007/S00262-011-0972-Z  0.45
2011 Xiao Y, Motomura S, Deyev V, Podack ER. TNF superfamily member 13, APRIL, inhibits allergic lung inflammation. European Journal of Immunology. 41: 164-71. PMID 21182087 DOI: 10.1002/Eji.201040436  0.614
2011 Schreiber TH, Wolf D, Podack ER. The role of TNFRSF25:TNFSF15 in disease… and health? Advances in Experimental Medicine and Biology. 691: 289-98. PMID 21153333 DOI: 10.1007/978-1-4419-6612-4_30  0.66
2011 Newman RG, Podack ER, Levy RB. Combining Early Heat Shock Protein Vaccination with Directed IL-2 Leads to Effective Anti-Tumor Immunity in Autologous Hematopoietic Cell Transplantation Recipients Blood. 118: 998-998. DOI: 10.1182/Blood.V118.21.998.998  0.509
2011 Schreiber TH, Khan SQ, Podack ER. Response to Taraban, Ferdinand, and Al-Shamkhani Journal of Clinical Investigation. 121: 465. DOI: 10.1172/Jci46113  0.783
2011 Zhang Y, Tadmor T, Eliav Y, Schreiber TH, Podack ER, Levy R, Shin S, Rosenblatt JD. Abstract LB-164: B lymphocytes inhibit anti-tumor response in a murine EMT6 tumor model by facilitating expansion of T regulatory cells Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-164  0.725
2010 Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y. CD30 ligand is a target for a novel biological therapy against colitis associated with Th17 responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 7671-80. PMID 21068411 DOI: 10.4049/Jimmunol.1002229  0.442
2010 Schreiber TH, Wolf D, Tsai MS, Chirinos J, Deyev VV, Gonzalez L, Malek TR, Levy RB, Podack ER. Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation. The Journal of Clinical Investigation. 120: 3629-40. PMID 20890040 DOI: 10.1172/Jci42933  0.814
2010 Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y. CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 2222-30. PMID 20639486 DOI: 10.4049/Jimmunol.1000024  0.48
2010 Schreiber TH, Raez L, Rosenblatt JD, Podack ER. Tumor immunogenicity and responsiveness to cancer vaccine therapy: the state of the art. Seminars in Immunology. 22: 105-12. PMID 20226686 DOI: 10.1016/J.Smim.2010.02.001  0.653
2010 Strbo N, Pahwa S, Kolber MA, Gonzalez L, Fisher E, Podack ER. Cell-secreted Gp96-Ig-peptide complexes induce lamina propria and intraepithelial CD8+ cytotoxic T lymphocytes in the intestinal mucosa. Mucosal Immunology. 3: 182-92. PMID 19924120 DOI: 10.1038/Mi.2009.127  0.69
2010 Podack E, Raez LE, Fisher E, Leibovitch E, Gomez JE, Baldie P, Tolba KA, Santos ES, Walker G. Novel tumor vaccine gp96-Ig fusion heat shock protein in advanced non-small cell lung cancer (NSCLC) patients who have failed palliative chemotherapy and erlotinib. Journal of Clinical Oncology. 28: e18042-e18042. DOI: 10.1200/Jco.2010.28.15_Suppl.E18042  0.401
2010 Newman RG, Podack ER, Levy RB. CD8 T Cell Expansion Early Post-Autologous HSCT Following Vaccination with Lymphoma Cells Secreting gp96-Ig and Augmentation by IL-2 Antibody Cytokine Complex Blood. 116: 4286-4286. DOI: 10.1182/Blood.V116.21.4286.4286  0.486
2010 Luna E, Fukata M, Strbo N, Abreu MT, Podack ER. Abstract 4769: Relevance of the TRIF pathway for in vivo gp96-mediated CD8+ T cell cross presentation Cancer Research. 70: 4769-4769. DOI: 10.1158/1538-7445.Am10-4769  0.468
2010 Podack ER. Lymphocyte‐Mediated Cytotoxicity Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0106  0.393
2009 Schreiber TH, Podack ER. A critical analysis of the tumour immunosurveillance controversy for 3-MCA-induced sarcomas. British Journal of Cancer. 101: 381-6. PMID 19638986 DOI: 10.1038/Sj.Bjc.6605198  0.656
2009 Schreiber TH, Deyev VV, Rosenblatt JD, Podack ER. Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination. Cancer Research. 69: 2026-33. PMID 19223534 DOI: 10.1158/0008-5472.Can-08-3706  0.713
2009 Gonzalez LE, Strbo N, Podack ER. P03-02. SCID-hu mice generate HIV specific human immune responses after gp96 vaccination Retrovirology. 6: 19. DOI: 10.1186/1742-4690-6-S3-P19  0.612
2009 Strbo N, Vaccari M, Pahwa S, Kolber MA, Fisher E, Gonzalez L, Felber BK, Pavlakis GN, Franchini G, Podack ER. OAO5-04. Gp96-Ig-SIV vaccines induce predominant immune responses at mucosal sites Retrovirology. 6: O34. DOI: 10.1186/1742-4690-6-S3-O34  0.639
2008 Xiao Y, Motomura S, Podack ER. APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response. European Journal of Immunology. 38: 3450-8. PMID 19016524 DOI: 10.1002/Eji.200838640  0.608
2008 Tang C, Yamada H, Shibata K, Muta H, Wajjwalku W, Podack ER, Yoshikai Y. A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 6316-27. PMID 18941223 DOI: 10.4049/Jimmunol.181.9.6316  0.481
2008 Fang L, Adkins B, Deyev V, Podack ER. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. The Journal of Experimental Medicine. 205: 1037-48. PMID 18411341 DOI: 10.1084/Jem.20072528  0.389
2008 Strbo N, Podack ER. Secreted heat shock protein gp96-Ig: an innovative vaccine approach. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 59: 407-16. PMID 18405311 DOI: 10.1111/J.1600-0897.2008.00594.X  0.365
2008 Oizumi S, Deyev V, Yamazaki K, Schreiber T, Strbo N, Rosenblatt J, Podack ER. Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 31: 394-401. PMID 18391756 DOI: 10.1097/Cji.0B013E31816Bc74D  0.725
2008 Sun X, Somada S, Shibata K, Muta H, Yamada H, Yoshihara H, Honda K, Nakamura K, Takayanagi R, Tani K, Podack ER, Yoshikai Y. A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology. 134: 447-58. PMID 18242212 DOI: 10.1053/J.Gastro.2007.11.004  0.445
2008 Nam SY, Kim YH, Do JS, Choi YH, Seo HJ, Yi HK, Hwang PH, Song CH, Lee HK, Kim JS, Podack ER. CD30 supports lung inflammation. International Immunology. 20: 177-84. PMID 18089617 DOI: 10.1093/Intimm/Dxm130  0.424
2007 Podack ER, Raez LE. Allogeneic tumor-cell-based vaccines secreting endoplasmic reticulum chaperone gp96. Expert Opinion On Biological Therapy. 7: 1679-88. PMID 17961091 DOI: 10.1517/14712598.7.11.1679  0.421
2007 Yi KH, Nechushtan H, Bowers WJ, Walker GR, Zhang Y, Pham DG, Podack ER, Federoff HJ, Tolba KA, Rosenblatt JD. Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo. Cancer Research. 67: 10027-37. PMID 17942937 DOI: 10.1158/0008-5472.Can-06-2391  0.444
2007 Oizumi S, Strbo N, Pahwa S, Deyev V, Podack ER. Molecular and cellular requirements for enhanced antigen cross-presentation to CD8 cytotoxic T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 2310-7. PMID 17675492 DOI: 10.4049/Jimmunol.179.4.2310  0.464
2006 Raez LE, Rosenblatt JD, Podack ER. Present and future of lung cancer vaccines. Expert Opinion On Emerging Drugs. 11: 445-59. PMID 16939384 DOI: 10.1517/14728214.11.3.445  0.342
2006 Lee KP, Raez LE, Podack ER. Heat shock protein-based cancer vaccines. Hematology/Oncology Clinics of North America. 20: 637-59. PMID 16762728 DOI: 10.1016/J.Hoc.2006.02.007  0.322
2006 Strbo N, Laskarin G, Bogovic Crncic T, Juretic Frankovic K, Bedenicki I, Sotosek Tokmadzic V, Randic L, Le Bouteiller P, Tabiasco J, Podack ER, Rukavina D. Short-term cytolytic mediators' expression in decidual lymphocytes is enhanced by interleukin-15. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 55: 217-25. PMID 16451356 DOI: 10.1111/J.1600-0897.2005.00351.X  0.315
2006 Deyev V, Roskos M, Levy RB, Podack ER. TNFR25 Expression on CD4+CD25+ T Cells: Down Modulation of Regulatory Activity. Blood. 108: 3165-3165. DOI: 10.1182/Blood.V108.11.3165.3165  0.488
2005 Raez LE, Fein S, Podack ER. Lung cancer immunotherapy. Clinical Medicine & Research. 3: 221-8. PMID 16303887 DOI: 10.3121/Cmr.3.4.221  0.376
2005 Nishimura H, Yajima T, Muta H, Podack ER, Tani K, Yoshikai Y. A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 4627-34. PMID 16177108 DOI: 10.4049/Jimmunol.175.7.4627  0.442
2005 Raez LE, Santos ES, Mudad R, Podack ER. Clinical trials targeting lung cancer with active immunotherapy: the scope of vaccines. Expert Review of Anticancer Therapy. 5: 635-44. PMID 16111464 DOI: 10.1586/14737140.5.4.635  0.339
2005 Zimmerman Z, Shatry A, Deyev V, Podack E, Mammolenti M, Blazar BR, Yagita H, Levy RB. Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 11: 576-86. PMID 16041307 DOI: 10.1016/J.Bbmt.2005.05.006  0.438
2005 Ahn ER, Podack E, Jy W, Bidot CJ, Horstman L, Ahn YS. Soluble CD30 (sCD30), a Marker of Th2 Polarization, Is Elevated in Patients with Autoimmune Hemolytic Anemia (AIHA) but Not with Idiopathic Thrombocytopenia (ITP). Blood. 106: 1248-1248. DOI: 10.1182/Blood.V106.11.1248.1248  0.387
2004 Blazar BR, Levy RB, Mak TW, Panoskaltsis-Mortari A, Muta H, Jones M, Roskos M, Serody JS, Yagita H, Podack ER, Taylor PA. CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 173: 2933-41. PMID 15322151 DOI: 10.4049/Jimmunol.173.5.2933  0.434
2004 Raez LE, Cassileth PA, Schlesselman JJ, Sridhar K, Padmanabhan S, Fisher EZ, Baldie PA, Podack ER. Allogeneic vaccination with a B7.1 HLA-A gene-modified adenocarcinoma cell line in patients with advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 2800-7. PMID 15254047 DOI: 10.1200/Jco.2004.10.197  0.379
2004 Marks L, Altman NH, Podack ER, Levy RB. Donor T cells lacking Fas ligand and perforin retain the capacity to induce severe GvHD in minor histocompatibility antigen mismatched bone-marrow transplantation recipients. Transplantation. 77: 804-12. PMID 15077018 DOI: 10.1097/01.Tp.0000110416.96307.D5  0.421
2004 Ahn ER, Podack ER, Lander G, Bidot CJ, Jy W, Ahn YS. Soluble CD30 Levels Are Highest in Autoimmune Hemolytic Anemia (AIHA) and Lymphoma among the Hematologic Disorders, but Are Not Elevated in ITP. Blood. 104: 3872-3872. DOI: 10.1182/Blood.V104.11.3872.3872  0.371
2004 Zimmerman Z, Jones A, Deyev V, Blazar B, Yagita H, Podack E, Levy R. Perforin, FasL, TNFR1, TWEAK, TRAIL, and DR3-TL1a are not required for efficient T cell mediated resistance against allogeneic bone marrow grafts Biology of Blood and Marrow Transplantation. 10: 39. DOI: 10.1016/J.Bbmt.2003.12.183  0.311
2003 Raez LE, Cassileth PA, Schlesselman JJ, Padmanabhan S, Fisher EZ, Baldie PA, Sridhar K, Podack ER. Induction of CD8 T-cell-Ifn-gamma response and positive clinical outcome after immunization with gene-modified allogeneic tumor cells in advanced non-small-cell lung carcinoma. Cancer Gene Therapy. 10: 850-8. PMID 14605671 DOI: 10.1038/Sj.Cgt.7700641  0.473
2003 Strbo N, Oizumi S, Sotosek-Tokmadzic V, Podack ER. Perforin is required for innate and adaptive immunity induced by heat shock protein gp96. Immunity. 18: 381-90. PMID 12648455 DOI: 10.1016/S1074-7613(03)00056-6  0.458
2003 Raez LE, Cassileth PA, Schlesselman J, Padmanabhan S, Fisher E, Baldie P, Sridhar K, Tang S, Podack E. O-152 Immunotherapy with gene-modified allogenic cells successfully induced CD8 T cell and clinical responses in patients with advanced non-small cell lung cancer (NSCLC) Lung Cancer. 41: S46-S47. DOI: 10.1016/S0169-5002(03)91810-1  0.413
2002 Podack ER, Strbo N, Sotosec V, Muta H. CD30-governor of memory T cells? Annals of the New York Academy of Sciences. 975: 101-13. PMID 12538158 DOI: 10.1111/J.1749-6632.2002.Tb05945.X  0.431
2002 Strbo N, Yamazaki K, Lee K, Rukavina D, Podack ER. Heat shock fusion protein gp96-Ig mediates strong CD8 CTL expansion in vivo. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 48: 220-5. PMID 12516632 DOI: 10.1034/J.1600-0897.2002.01118.X  0.459
2002 Laskarin G, Tokmadzić VS, Strbo N, Bogović T, Szekeres-Bartho J, Randić L, Podack ER, Rukavina D. Progesterone induced blocking factor (PIBF) mediates progesterone induced suppression of decidual lymphocyte cytotoxicity. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 48: 201-9. PMID 12516630 DOI: 10.1034/J.1600-0897.2002.01133.X  0.355
2002 Tokmadzić VS, Tsuji Y, Bogović T, Laskarin G, Cupurdija K, Strbo N, Koyama K, Okamura H, Podack ER, Rukavina D. IL-18 is present at the maternal-fetal interface and enhances cytotoxic activity of decidual lymphocytes. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 48: 191-200. PMID 12516629 DOI: 10.1034/J.1600-0897.2002.01132.X  0.302
2002 Nam SY, Cho KS, Heo YM, Ha JC, Kim YH, Keun Yi H, Han Hwang P, Kim HM, Podack ER. Regulation of lymphocyte clustering by CD30-mediated ICAM-1 up-regulation. Cellular Immunology. 219: 38-47. PMID 12473266 DOI: 10.1016/S0008-8749(02)00583-X  0.463
2002 Pár G, Rukavina D, Podack ER, Horányi M, Szekeres-Barthó J, Hegedüs G, Paál M, Szereday L, Mózsik G, Pár A. Decrease in CD3-negative-CD8dim(+) and Vdelta2/Vgamma9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection. Journal of Hepatology. 37: 514-22. PMID 12217606 DOI: 10.1016/S0168-8278(02)00218-0  0.403
2002 Harlin H, Podack E, Boothby M, Alegre ML. TCR-independent CD30 signaling selectively induces IL-13 production via a TNF receptor-associated factor/p38 mitogen-activated protein kinase-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 169: 2451-9. PMID 12193714 DOI: 10.4049/Jimmunol.169.5.2451  0.421
2002 Metkar SS, Wang B, Aguilar-Santelises M, Raja SM, Uhlin-Hansen L, Podack E, Trapani JA, Froelich CJ. Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation Immunity. 16: 417-428. PMID 11911826 DOI: 10.1016/S1074-7613(02)00286-8  0.316
2002 Strbo, Natasa, Laskarin, Gordana, Sotosek-Tokmandzic, Vlatka, Bogovic-Crncic, Tatjana, Cupurdija, Kristijan, Juretic, Koraljka, Dorcic, Dora, Dupor, ... ... Podack ER, et al. Characterisation of antigen presenting cells in the human first trimester decidua American Journal of Reproductive Immunology. 48: 160-160. DOI: 10.1034/J.1600-0897.2002.T01-1-00019.X  0.349
2001 Podack ER. Control of Cytotoxic Lymphocyte Survival in Vivo By Members of the TNF-R Family. Thescientificworldjournal. 1: 103. PMID 30147581 DOI: 10.1100/Tsw.2001.126  0.488
2001 Toomey NL, Deyev VV, Wood C, Boise LH, Scott D, Liu LH, Cabral L, Podack ER, Barber GN, Harrington WJ. Induction of a TRAIL mediated suicide program by interferon alpha in primary effusion lymphoma Oncogene. 20: 7029-7040. PMID 11704827 DOI: 10.1038/Sj.Onc.1204895  0.306
2001 Ohshima K, Kawasaki C, Muta H, Muta K, Deyev V, Haraoka S, Suzumiya J, Podack ER, Kikuchi M. CD10 and Bcl10 expression in diffuse large B-cell lymphoma: CD10 is a marker of improved prognosis. Histopathology. 39: 156-62. PMID 11493332 DOI: 10.1046/J.1365-2559.2001.01196.X  0.382
2001 Jiang Z, Podack E, Levy RB. Major histocompatibility complex-mismatched allogeneic bone marrow transplantation using perforin and/or Fas ligand double-defective CD4(+) donor T cells: involvement of cytotoxic function by donor lymphocytes prior to graft-versus-host disease pathogenesis. Blood. 98: 390-7. PMID 11435308 DOI: 10.1182/Blood.V98.2.390  0.431
2000 Prpić L, Strbo N, Sotosek V, Gruber F, Podack ER, Rukavina D. Assessment of perforin expression in peripheral blood lymphocytes in psoriatic patients during exacerbation of disease. Acta Dermato-Venereologica. Supplementum. 14-6. PMID 11234556 DOI: 10.1080/00015550050500059  0.464
2000 Muta H, Boise LH, Fang L, Podack ER. CD30 signals integrate expression of cytotoxic effector molecules, lymphocyte trafficking signals, and signals for proliferation and apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 165: 5105-11. PMID 11046041 DOI: 10.4049/Jimmunol.165.9.5105  0.43
2000 Laskarin G, Strbo N, Sotosek V, Rukavina D, Faust Z, Szekeres-Bartho J, Podack ER. Progesterone directly and indirectly affects perforin expression in cytolytic cells. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 42: 312-20. PMID 10584987 DOI: 10.1111/J.1600-0897.1999.Tb00107.X  0.302
2000 Yamazaki K, Podack E, Ogura S, Dosaka-Akita H, Kawakami Y. Induction of tumor immunity by gp96 secreted from engineered tumor cells Lung Cancer. 29: 185. DOI: 10.1016/S0169-5002(00)80623-6  0.358
2000 Merger M, Zysman MA, Borojevic R, Podack ER, Croitoru K. Combined absence of perforin and FasL in perf -/- x gld mice significantly decreases anti-CD3 induced enteropathy Gastroenterology. 118: A95. DOI: 10.1016/S0016-5085(00)82456-7  0.346
1999 Schoell WM, Mirhashemi R, Liu B, Janicek MF, Podack ER, Penalver MA, Averette HE. Generation of tumor-specific cytotoxic T lymphocytes by stimulation with HPV type 16 E7 peptide-pulsed dendritic cells: an approach to immunotherapy of cervical cancer. Gynecologic Oncology. 74: 448-55. PMID 10479508 DOI: 10.1006/Gyno.1999.5504  0.311
1999 Strbo N, Laskarin G, Sotosek V, Randić LJ, Podack ER, Rukavina D. Modulation of perforin expression in the decidual and peripheral blood cytotoxic lymphocytes in culture. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 42: 14-21. PMID 10429762 DOI: 10.1111/J.1600-0897.1999.Tb00460.X  0.302
1999 Podack ER. How to induce involuntary suicide: the need for dipeptidyl peptidase I. Proceedings of the National Academy of Sciences of the United States of America. 96: 8312-4. PMID 10411865 DOI: 10.1073/Pnas.96.15.8312  0.375
1999 Sotošek V, Laškarin G, Štrbo N, Dohr G, Blaschitz A, Podack ER, Rukavina D. Decidual macrophages are the population of decidual adherent cells which regulates perforin expression in cytolytic cells. American Journal of Reproductive Immunology. 42: 76-82. DOI: 10.1111/J.1600-0897.1999.Tb00469.X  0.353
1998 Bennett M, Taylor PA, Austin M, Baker MB, Schook LB, Rutherford M, Kumar V, Podack ER, Mohler KM, Levy RB, Blazar BR. Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: influence of mouse colony environment. International Immunology. 10: 785-90. PMID 9678759 DOI: 10.1093/Intimm/10.6.785  0.377
1998 Telford WG, Nam SY, Podack ER, Miller RA. CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals. Cellular Immunology. 182: 125-36. PMID 9514701 DOI: 10.1006/Cimm.1997.1228  0.476
1998 Rukavina D, Laskarin G, Rubesa G, Strbo N, Bedenicki I, Manestar D, Glavas M, Christmas SE, Podack ER. Age-Related Decline of Perforin Expression in Human Cytotoxic T Lymphocytes and Natural Killer Cells Blood. 92: 2410-2420. DOI: 10.1182/Blood.V92.7.2410  0.441
1997 Uellner R, Zvelebil MJ, Hopkins J, Jones J, MacDougall LK, Morgan BP, Podack E, Waterfield MD, Griffiths GM. Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain. The Embo Journal. 16: 7287-96. PMID 9405358 DOI: 10.1093/Emboj/16.24.7287  0.343
1997 Rukavina D, Podack ER, Rubesa G, Spanjol-Pandelo S, Randic L. Down-regulated expression of perforin-positive/CD16+ cells in the peripheral blood lymphocytes in the first trimester of pregnancy and up-regulation at the end of pregnancy. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 38: 189-96. PMID 9325491 DOI: 10.1111/J.1600-0897.1997.Tb00297.X  0.311
1997 Gudelj L, Christmas SE, Laskarin G, Johnson PM, Podack ER, Rukavina D. Membrane phenotype and expression of perforin and serine esterases by CD3- peripheral blood and decidual granular lymphocyte-derived clones. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 38: 162-7. PMID 9325487 DOI: 10.1111/J.1600-0897.1997.Tb00293.X  0.366
1997 Ivanov VN, Lee RK, Podack ER, Malek TR. Regulation of Fas-dependent activation-induced T cell apoptosis by cAMP signaling: A potential role for transcription factor NF-κB Oncogene. 14: 2455-2464. PMID 9188860 DOI: 10.1038/Sj.Onc.1201088  0.343
1997 Rubesa G, Podack ER, Sepcić J, Rukavina D. Increased perforin expression in multiple sclerosis patients during exacerbation of disease in peripheral blood lymphocytes. Journal of Neuroimmunology. 74: 198-204. PMID 9119974 DOI: 10.1016/S0165-5728(96)00236-6  0.379
1997 Baker MB, Riley RL, Podack ER, Levy RB. Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function. Proceedings of the National Academy of Sciences of the United States of America. 94: 1366-71. PMID 9037059 DOI: 10.1073/Pnas.94.4.1366  0.398
1997 Pericle F, Epling-Burnette PK, Podack ER, Wei S, Djeu JY. CD40-CD40L interactions provide "third-party" costimulation for T cell response against B7-1-transfected human breast tumor cells. Journal of Leukocyte Biology. 61: 201-8. PMID 9021926 DOI: 10.1002/Jlb.61.2.201  0.471
1997 Chen PW, Geer DC, Podack ER, Ksander BR. Tumor cells transfected with B7-1 and interleukin-12 cDNA induce protective immunity. Annals of the New York Academy of Sciences. 795: 325-7. PMID 8958945 DOI: 10.1111/J.1749-6632.1996.Tb52683.X  0.404
1997 Stohl W, Elliott JE, Li L, Podack ER, Lynch DH, Jacob CO. Impaired nonrestricted cytolytic activity in systemic lupus erythematosus Arthritis & Rheumatism. 40: 1130-1137. DOI: 10.1002/Art.1780400618  0.351
1996 Nishio M, Podack ER. Rapid induction of tumor necrosis factor cytotoxicity in naive splenic T cells by simultaneous CD80 (B7.1) and CD54 (ICAM-1) co-stimulation European Journal of Immunology. 26: 2160-2164. PMID 8814262 DOI: 10.1002/Eji.1830260930  0.479
1996 Lee RK, Spielman J, Podack ER. bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis International Immunology. 8: 991-1000. PMID 8757944 DOI: 10.1093/Intimm/8.7.991  0.372
1996 Baker MB, Altman NH, Podack ER, Levy RB. The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice. The Journal of Experimental Medicine. 183: 2645-56. PMID 8676085 DOI: 10.1084/Jem.183.6.2645  0.368
1996 Hameed A, Fox WM, Kurman RJ, Hruban RH, Podack ER. Perforin expression in human cell-mediated luteolysis. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 14: 151-7. PMID 8601527 DOI: 10.1097/00004347-199504000-00009  0.466
1996 Hameed A, Fox WM, Kurman RJ, Hruban RH, Podack ER. Perforin expression in endometrium during the menstrual cycle. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 14: 143-50. PMID 8601526 DOI: 10.1097/00004347-199504000-00008  0.437
1996 Rukavina D, Balen-Marunic S, Rubesa G, Orlic P, Vujaklija K, Podack ER. Perforin expression in peripheral blood lymphocytes in rejecting and tolerant kidney transplant recipients. Transplantation. 61: 285-91. PMID 8600638 DOI: 10.1097/00007890-199601270-00021  0.419
1996 Ivanov VN, Deng G, Podack ER, Malek TR. Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-kappa B p50-p50 for the anti-apoptotic function of Bcl-2. International Immunology. 7: 1709-20. PMID 8580069 DOI: 10.1093/Intimm/7.11.1709  0.316
1995 Levy RB, Baker M, Podack ER. Perforin-deficient T cells can induce acute graft-versus-host disease after transplantation of MHC-matched or MHC disparate allogeneic bone marrow. Annals of the New York Academy of Sciences. 770: 366-7. PMID 8597376 DOI: 10.1111/J.1749-6632.1995.Tb31070.X  0.31
1995 Cassileth PA, Podack E, Sridhar K, Savaraj N, Hanlon J. Phase I Study of Transfected Cancer Cells Expressing the Interleukin-2 Gene Product in Limited Stage Small Cell Lung Cancer. University of Miami, Miami, Florida Human Gene Therapy. 6: 369-383. PMID 7779919 DOI: 10.1089/Hum.1995.6.3-369  0.303
1995 Ohe Y, Zhao D, Saijo N, Podack ER. Construction of a novel bovine papillomavirus vector without detectable transforming activity suitable for gene transfer. Human Gene Therapy. 6: 325-33. PMID 7779916 DOI: 10.1089/Hum.1995.6.3-325  0.305
1995 Podack ER. Perforin, killer cells and gene transfer immunotherapy for cancer. Current Topics in Microbiology and Immunology. 198: 121-30. PMID 7774277 DOI: 10.1007/978-3-642-79414-8_7  0.435
1995 Deng G, Podack ER. Deoxyribonuclease induction in apoptotic cytotoxic T lymphocytes Faseb Journal. 9: 665-669. PMID 7768359 DOI: 10.1096/Fasebj.9.8.7768359  0.329
1995 Isaaz S, Baetz K, Olsen K, Podack E, Griffiths GM. Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway. European Journal of Immunology. 25: 1071-9. PMID 7737276 DOI: 10.1002/Eji.1830250432  0.402
1995 Podack ER. Functional significance of two cytolytic pathways of cytotoxic T lymphocytes. Journal of Leukocyte Biology. 57: 548-52. PMID 7722413 DOI: 10.1002/Jlb.57.4.548  0.403
1995 Konjevic G, Schlesinger B, Cheng L, Olsen KJ, Podack ER, Spuzic I. Analysis of perforin expression in human peripheral blood lymphocytes, CD 56+ natural killer cell subsets and its induction by interleukin-2 Immunological Investigations. 24: 499-507. PMID 7540593 DOI: 10.3109/08820139509066846  0.431
1995 Podack ER. Execution and suicide: cytotoxic lymphocytes enforce Draconian laws through separate molecular pathways. Current Opinion in Immunology. 7: 11-6. PMID 7539615 DOI: 10.1016/0952-7915(95)80023-9  0.432
1994 Kägi D, Ledermann B, Bürki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature. 369: 31-7. PMID 8164737 DOI: 10.1038/369031A0  0.465
1994 Wu Z, Podack ER, McKenzie JM, Olsen KJ, Zakarija M. Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease Clinical and Experimental Immunology. 98: 470-477. PMID 7994911 DOI: 10.1111/j.1365-2249.1994.tb05515.x  0.326
1994 Ohira T, Ohe Y, Heike Y, Podack ER, Olsen KJ, Nishio K, Nishio M, Miyahara Y, Funayama Y, Ogasawara H, Arioka H, Kunikane H, Fukuda M, Kato H, Saijo N. In vitro and in vivo growth of B16F10 melanoma cells transfected with interleukin-4 cDNA and gene therapy with the transfectant Journal of Cancer Research and Clinical Oncology. 120: 631-635. PMID 7962038 DOI: 10.1007/Bf01245372  0.34
1993 Deng G, Podack ER. Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2 Proceedings of the National Academy of Sciences of the United States of America. 90: 2189-2193. PMID 8460122 DOI: 10.1073/Pnas.90.6.2189  0.334
1993 Ohe Y, Podack ER, Olsen KJ, Miyahara Y, Ohira T, Miura K, Nishio K, Saijo N. Combination effect of vaccination with IL2 and IL4 cDNA transfected cells on the induction of a therapeutic immune response against Lewis lung carcinoma cells International Journal of Cancer. 53: 432-437. PMID 8428797 DOI: 10.1002/Ijc.2910530314  0.333
1993 García-Sanz JA, Podack ER. Regulation of perforin gene expression in a T cell hybrid with inducible cytolytic activity. European Journal of Immunology. 23: 1877-83. PMID 8344349 DOI: 10.1002/Eji.1830230822  0.31
1992 Podack ER, Kupfer A. T-cell effector functions: mechanisms for delivery of cytotoxicity and help. Annual Review of Cell Biology. 7: 479-504. PMID 1839711 DOI: 10.1146/Annurev.Cb.07.110191.002403  0.384
1992 Nelson PJ, Geller RL, Podack E, Bach FH. Molecular events in late stages of T-cell functional maturation. Scandinavian Journal of Immunology. 35: 311-320. PMID 1535987 DOI: 10.1111/J.1365-3083.1992.Tb02863.X  0.393
1992 Keane RW, Tallent MW, Podack ER. Resistance and susceptibility of neural cells to lysis by cytotoxic lymphocytes and by cytolytic granules. Transplantation. 54: 520-6. PMID 1412733 DOI: 10.1097/00007890-199209000-00025  0.355
1991 Podack ER, Hengartner H, Lichtenheld MG. A central role of perforin in cytolysis? Annual Review of Immunology. 9: 129-57. PMID 1910674 DOI: 10.1146/Annurev.Iy.09.040191.001021  0.366
1990 Podack ER. Killer lymphocytes and how they kill. Current Opinion in Cell Biology. 1: 929-33. PMID 2697296 DOI: 10.1016/0955-0674(89)90060-4  0.377
1990 Bach FH, Geller RL, Nelson PJ, Panzer S, Gromo G, Benfield MR, Inverardi L, Podack ER, Witson JC, Houchins JP. A "minimal signal-stepwise activation" analysis of functional maturation of T lymphocytes. Immunological Reviews. 111: 35-57. PMID 2534115 DOI: 10.1111/J.1600-065X.1989.Tb00541.X  0.329
1990 Ascensao JL, Liu SJ, Caro J, Podack E, Mittelman A, Zanjani ED, Zhao YL. Erythropoiesis in cancer patients undergoing immunotherapy Advances in Experimental Medicine and Biology. 271: 197-204. PMID 2518599 DOI: 10.1007/978-1-4613-0623-8_20  0.325
1990 Podack ER, Lichtenheld MG. Chapter 14 Perforin and the Mechanism of Lymphocyte-Mediated Cytolysis Current Topics in Membranes and Transport. 36: 161-175. DOI: 10.1016/S0070-2161(08)60176-8  0.379
1989 Lowrey DM, Aebischer T, Olsen K, Lichtenheld M, Rupp F, Hengartner H, Podack ER. Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9. Proceedings of the National Academy of Sciences of the United States of America. 86: 247-51. PMID 2783486 DOI: 10.1073/Pnas.86.1.247  0.331
1989 Müller C, Kägi D, Aebischer T, Odermatt B, Held W, Podack ER, Zinkernagel RM, Hengartner H. Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus. European Journal of Immunology. 19: 1253-9. PMID 2668013 DOI: 10.1002/Eji.1830190716  0.38
1989 Podack ER, Olsen KJ, Lowrey DM, Lichtenheld M. Structure and function of perforin Current Topics in Microbiology and Immunology. 140: 11-17. PMID 2644072 DOI: 10.1007/978-3-642-73911-8_2  0.315
1989 Podack ER. Granule-mediated cytolysis of target cells. Current Topics in Microbiology and Immunology. 140: 1-9. PMID 2644070 DOI: 10.1007/978-3-642-73911-8_1  0.353
1988 Podack ER, Lowrey DM, Lichtenheld M, Hameed A. Function of granule perforin and esterases in T cell-mediated reactions. Components required for delivery of molecules to target cells. Annals of the New York Academy of Sciences. 532: 292-302. PMID 2972243 DOI: 10.1111/J.1749-6632.1988.Tb36347.X  0.415
1987 Lowrey DM, Rupp F, Aebischer T, Grey P, Hengartner H, Podack ER. Primary sequence homology between the effector molecules that mediate complement and T-lymphocyte cytotoxicity. Annales De L'Institut Pasteur. Immunology. 138: 296-300. PMID 3496905 DOI: 10.1016/S0769-2625(87)80082-X  0.347
1986 Young JD, Cohn ZA, Podack ER. The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities. Science (New York, N.Y.). 233: 184-90. PMID 2425429 DOI: 10.1126/Science.2425429  0.346
1986 Young JD, Podack ER, Cohn ZA. Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules. The Journal of Experimental Medicine. 164: 144-55. PMID 2425027 DOI: 10.1084/Jem.164.1.144  0.334
1985 Podack ER, Konigsberg PJ, Acha-Orbea H, Pircher H, Hengartner H. Cytolytic T-cell granules: biochemical properties and functional specificity. Advances in Experimental Medicine and Biology. 184: 99-119. PMID 3875979 DOI: 10.1007/978-1-4684-8326-0_8  0.337
1985 Podack ER, Young JD, Cohn ZA. Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proceedings of the National Academy of Sciences of the United States of America. 82: 8629-33. PMID 2417226 DOI: 10.1073/Pnas.82.24.8629  0.314
1984 Podack ER, Konigsberg PJ. Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization. The Journal of Experimental Medicine. 160: 695-710. PMID 6332169 DOI: 10.1084/Jem.160.3.695  0.365
1982 Harriman G, Curd J, Podack E, Braude A, Lint T, Esser A. Complement mediated killing of neisseria Molecular Immunology. 19: 1374. DOI: 10.1016/0161-5890(82)90062-1  0.3
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