Year |
Citation |
Score |
2020 |
Choi J, Zhang T, Vu A, Ablain J, Makowski MM, Colli LM, Xu M, Hennessey RC, Yin J, Rothschild H, Gräwe C, Kovacs MA, Funderburk KM, Brossard M, Taylor J, ... ... Brown KM, et al. Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature Communications. 11: 2718. PMID 32483191 DOI: 10.1038/S41467-020-16590-1 |
0.301 |
|
2020 |
Landi MT, Bishop DT, MacGregor S, Machiela MJ, Stratigos AJ, Ghiorzo P, Brossard M, Calista D, Choi J, Fargnoli MC, Zhang T, Rodolfo M, Trower AJ, Menin C, Martinez J, ... ... Brown KM, et al. Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nature Genetics. PMID 32341527 DOI: 10.1038/S41588-020-0611-8 |
0.317 |
|
2020 |
Brown KM, Sibley LD, Lourido S. High-Throughput Measurement of Microneme Secretion in Toxoplasma gondii. Methods in Molecular Biology (Clifton, N.J.). 2071: 157-169. PMID 31758452 DOI: 10.1007/978-1-4939-9857-9_9 |
0.313 |
|
2018 |
Brown KM, Sibley LD. Essential cGMP Signaling in Toxoplasma Is Initiated by a Hybrid P-Type ATPase-Guanylate Cyclase. Cell Host & Microbe. PMID 30449726 DOI: 10.1016/J.Chom.2018.10.015 |
0.31 |
|
2018 |
Zhang T, Choi J, Kovacs MA, Shi J, Xu M, Goldstein AM, Trower AJ, Bishop DT, Iles MM, Duffy DL, MacGregor S, Amundadottir LT, Law MH, ... ... Brown KM, et al. Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes. Genome Research. PMID 30333196 DOI: 10.1101/Gr.233304.117 |
0.302 |
|
2015 |
Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, ... ... Brown KM, et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Research. PMID 26603897 DOI: 10.1158/0008-5472.Can-15-0885 |
0.309 |
|
2014 |
Song F, Amos CI, Lee JE, Lian CG, Fang S, Liu H, MacGregor S, Iles MM, Law MH, Lindeman NI, Montgomery GW, Duffy DL, Cust AE, Jenkins MA, Whiteman DC, ... ... Brown KM, et al. Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 35: 2097-101. PMID 24980573 DOI: 10.1093/Carcin/Bgu140 |
0.313 |
|
2014 |
Brown KM, Suvorova E, Farrell A, McLain A, Dittmar A, Wiley GB, Marth G, Gaffney PM, Gubbels MJ, White M, Blader IJ. Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases. Plos Pathogens. 10: e1004180. PMID 24945800 DOI: 10.1371/Journal.Ppat.1004180 |
0.732 |
|
2014 |
Farrell A, Coleman BI, Benenati B, Brown KM, Blader IJ, Marth GT, Gubbels MJ. Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii. Bmc Genomics. 15: 354. PMID 24885922 DOI: 10.1186/1471-2164-15-354 |
0.654 |
|
2014 |
Brown KM, Suvorova E, Farrell A, McLain A, Dittmar A, Wiley GB, Marth G, Gaffney PM, Gubbels MJ, White M, Blader IJ. Forward Genetic Screening Identifies a Small Molecule That Blocks Toxoplasma gondii Growth by Inhibiting Both Host- and Parasite-Encoded Kinases Plos Pathogens. 10. DOI: 10.1371/journal.ppat.1004180 |
0.724 |
|
2013 |
Yin H, Chow D, Sereduk C, Aziz M, Kim S, Brown KM, Trent JM. Abstract 3151: High-throughput RNAi screening identifies a novel metastatic melanoma drug target in the context of PTEN mutation. Cancer Research. 73: 3151-3151. DOI: 10.1158/1538-7445.Am2013-3151 |
0.311 |
|
2012 |
Xu Y, Brown KM, Wang ZA, van der Wel H, Teygong C, Zhang D, Blader IJ, West CM. The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium. The Journal of Biological Chemistry. 287: 25098-110. PMID 22648409 DOI: 10.1074/Jbc.M112.355446 |
0.636 |
|
2012 |
MacGregor S, Brown K, Stark M, Gartside M, Woods S, Bonazzi V, Aoude L, Dutton-Regester K, Tyagi S, Liu J, Duffy D, Palmer J, Cust A, Schmid H, Symmons J, et al. From GWAS to genome sequencing: complementary approaches to identify melanoma predisposition genes Hereditary Cancer in Clinical Practice. 10: A46. DOI: 10.1186/1897-4287-10-S2-A46 |
0.317 |
|
2011 |
Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, ... ... Brown KM, et al. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 480: 99-103. PMID 22080950 DOI: 10.1038/Nature10630 |
0.309 |
|
2011 |
Brooks BR, Yin H, Chow D, Sereduk C, Koeman J, Qian C, MacKeigan JP, Jung S, Kim S, Xu M, Weeraratna A, Brown KM, Trent J. Abstract 4984: Association ofPTENandp16mutational status withMITFexpression may provide a novel context for a phenotype switch in melanoma Cancer Research. 71: 4984-4984. DOI: 10.1158/1538-7445.Am2011-4984 |
0.311 |
|
2010 |
Wiley M, Sweeney KR, Chan DA, Brown KM, McMurtrey C, Howard EW, Giaccia AJ, Blader IJ. Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling. The Journal of Biological Chemistry. 285: 26852-60. PMID 20581113 DOI: 10.1074/Jbc.M110.147041 |
0.714 |
|
2009 |
Brown KM, Blader IJ. The role of DNA microarrays in Toxoplasma gondii research, the causative agent of ocular toxoplasmosis. Journal of Ocular Biology, Diseases, and Informatics. 2: 214-222. PMID 20157353 DOI: 10.1007/S12177-009-9040-8 |
0.659 |
|
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