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Simon WM John, P.h.D. - Publications

Affiliations: 
The Jackson Laboratory, Bar Harbor, ME, United States 
Area:
Glaucoma, genetics
Website:
http://www.simonjohnlab.org/dr-simon-wm-john
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Paylakhi S, Labelle-Dumais C, Tolman NG, Sellarole MA, Seymens Y, Saunders J, Lakosha H, deVries WN, Orr AC, Topilko P, John SW, Nair KS. Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error. Plos Genetics. 14: e1007244. PMID 29529029 DOI: 10.1371/Journal.Pgen.1007244  0.393
2017 Thomson BR, Souma T, Tompson SW, Onay T, Kizhatil K, Siggs OM, Feng L, Whisenhunt KN, Yanovitch TL, Kalaydjieva L, Azmanov DN, Finzi S, Tanna CE, Hewitt AW, Mackey DA, ... ... John SW, et al. Angiopoietin-1 is required for Schlemm's canal development in mice and humans. The Journal of Clinical Investigation. PMID 29106382 DOI: 10.1172/Jci95545  0.319
2017 Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porciatti V, Smithies O, John SW. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science (New York, N.Y.). 355: 756-760. PMID 28209901 DOI: 10.1126/Science.Aal0092  0.453
2016 Nair KS, Cosma M, Raghupathy N, Sellarole MA, Tolman NG, de Vries W, Smith RS, John SW. YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17. Disease Models & Mechanisms. PMID 27483353 DOI: 10.1242/Dmm.024307  0.363
2016 Souma T, Tompson SW, Thomson BR, Siggs OM, Kizhatil K, Yamaguchi S, Feng L, Limviphuvadh V, Whisenhunt KN, Maurer-Stroh S, Yanovitch TL, Kalaydjieva L, Azmanov DN, Finzi S, Mauri L, ... ... John S, et al. Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. The Journal of Clinical Investigation. PMID 27270174 DOI: 10.1172/Jci85830  0.463
2016 Alavi MV, Mao M, Pawlikowski BT, Kvezereli M, Duncan JL, Libby RT, John SW, Gould DB. Col4a1 mutations cause progressive retinal neovascular defects and retinopathy. Scientific Reports. 6: 18602. PMID 26813606 DOI: 10.1038/Srep18602  0.626
2015 Mao M, Smith RS, Alavi MV, Marchant JK, Cosma M, Libby RT, John SW, Gould DB. Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice. Investigative Ophthalmology & Visual Science. 56: 6823-6831. PMID 26567795 DOI: 10.1167/Iovs.15-17527  0.639
2015 Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT. Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities. Experimental Eye Research. PMID 26116903 DOI: 10.1016/J.Exer.2015.06.019  0.305
2014 Cross SH, Macalinao DG, McKie L, Rose L, Kearney AL, Rainger J, Thaung C, Keighren M, Jadeja S, West K, Kneeland SC, Smith RS, Howell GR, Young F, Robertson M, ... ... John SW, et al. A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LBD1-mediated dimerisation. Plos Genetics. 10: e1004359. PMID 24809698 DOI: 10.1371/journal.pgen.1004359  0.372
2011 Nair KS, Hmani-Aifa M, Ali Z, Kearney AL, Ben Salem S, Macalinao DG, Cosma IM, Bouassida W, Hakim B, Benzina Z, Soto I, Söderkvist P, Howell GR, Smith RS, Ayadi H, ... John SW, et al. Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice. Nature Genetics. 43: 579-84. PMID 21532570 DOI: 10.1038/ng.813  0.33
2011 Veth KN, Willer JR, Collery RF, Gray MP, Willer GB, Wagner DS, Mullins MC, Udvadia AJ, Smith RS, John SW, Gregg RG, Link BA. Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma. Plos Genetics. 7: e1001310. PMID 21379331 DOI: 10.1371/Journal.Pgen.1001310  0.349
2011 Mao M, Hedberg-Buenz A, Koehn D, John SW, Anderson MG. Anterior segment dysgenesis and early-onset glaucoma in nee mice with mutation of Sh3pxd2b. Investigative Ophthalmology & Visual Science. 52: 2679-88. PMID 21282566 DOI: 10.1167/Iovs.10-5993  0.323
2009 Lee B, Bokryeon L, Kano K, Young J, John SW, Nishina PM, Naggert JK, Naito K. A novel ENU-induced mutation, peewee, causes dwarfism in the mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 404-13. PMID 19513787 DOI: 10.1007/S00335-009-9197-2  0.453
2008 Anderson MG, Hawes NL, Trantow CM, Chang B, John SW. Iris phenotypes and pigment dispersion caused by genes influencing pigmentation. Pigment Cell & Melanoma Research. 21: 565-78. PMID 18715234 DOI: 10.1111/j.1755-148X.2008.00482.x  0.318
2008 Anderson MG, Nair KS, Amonoo LA, Mehalow A, Trantow CM, Masli S, John SW. GpnmbR150X allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma. Bmc Genetics. 9: 30. PMID 18402690 DOI: 10.1186/1471-2156-9-30  0.333
2008 Weng Y, Dilworth DJ, Libby RT, John SW, Gould DB. Mutant COL4A1 triggers oxidative stress in a genetic model of AMD Matrix Biology. 27: 39. DOI: 10.1016/J.Matbio.2008.09.339  0.539
2007 Brooks BP, Larson DM, Chan CC, Kjellstrom S, Smith RS, Crawford MA, Lamoreux L, Huizing M, Hess R, Jiao X, Hejtmancik JF, Maminishkis A, John SW, Bush R, Pavan WJ. Analysis of ocular hypopigmentation in Rab38cht/cht mice. Investigative Ophthalmology & Visual Science. 48: 3905-13. PMID 17724166 DOI: 10.1167/Iovs.06-1464  0.346
2007 Howell GR, Libby RT, Marchant JK, Wilson LA, Cosma IM, Smith RS, Anderson MG, John SW. Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1. Bmc Genetics. 8: 45. PMID 17608931 DOI: 10.1186/1471-2156-8-45  0.338
2007 Gould DB, Marchant JK, Savinova OV, Smith RS, John SW. Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis. Human Molecular Genetics. 16: 798-807. PMID 17317786 DOI: 10.1093/hmg/ddm024  0.624
2006 Gould DB, Reedy M, Wilson LA, Smith RS, Johnson RL, John SW. Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma. Molecular and Cellular Biology. 26: 8427-36. PMID 16954374 DOI: 10.1128/MCB.01127-06  0.645
2006 Anderson MG, Libby RT, Mao M, Cosma IM, Wilson LA, Smith RS, John SW. Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. Bmc Biology. 4: 20. PMID 16827931 DOI: 10.1186/1741-7007-4-20  0.339
2006 Gould DB, Phalan FC, van Mil SE, Sundberg JP, Vahedi K, Massin P, Bousser MG, Heutink P, Miner JH, Tournier-Lasserve E, John SW. Role of COL4A1 in small-vessel disease and hemorrhagic stroke. The New England Journal of Medicine. 354: 1489-96. PMID 16598045 DOI: 10.1056/NEJMoa053727  0.611
2005 Libby RT, Anderson MG, Pang IH, Robinson ZH, Savinova OV, Cosma IM, Snow A, Wilson LA, Smith RS, Clark AF, John SW. Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Visual Neuroscience. 22: 637-48. PMID 16332275 DOI: 10.1017/S0952523805225130  0.302
2005 Hagaman JR, John S, Xu L, Smithies O, Maeda N. An improved technique for tail-cuff blood pressure measurements with dark-tailed mice. Contemporary Topics in Laboratory Animal Science / American Association For Laboratory Animal Science. 44: 43-6. PMID 16138782  0.478
2005 Libby RT, Gould DB, Anderson MG, John SW. Complex genetics of glaucoma susceptibility. Annual Review of Genomics and Human Genetics. 6: 15-44. PMID 16124852 DOI: 10.1146/Annurev.Genom.6.080604.162209  0.601
2005 Gould DB, Phalan FC, Breedveld GJ, van Mil SE, Smith RS, Schimenti JC, Aguglia U, van der Knaap MS, Heutink P, John SW. Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly. Science (New York, N.Y.). 308: 1167-71. PMID 15905400 DOI: 10.1126/science.1109418  0.622
2005 Anderson MG, Libby RT, Gould DB, Smith RS, John SW. High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma. Proceedings of the National Academy of Sciences of the United States of America. 102: 4566-71. PMID 15758074 DOI: 10.1073/Pnas.0407357102  0.571
2004 Gould DB, Smith RS, John SW. Anterior segment development relevant to glaucoma. The International Journal of Developmental Biology. 48: 1015-29. PMID 15558492 DOI: 10.1387/ijdb.041865dg  0.581
2004 Gould DB, Miceli-Libby L, Savinova OV, Torrado M, Tomarev SI, Smith RS, John SW. Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma. Molecular and Cellular Biology. 24: 9019-25. PMID 15456875 DOI: 10.1128/MCB.24.20.9019-9025.2004  0.618
2003 Lehmann OJ, Tuft S, Brice G, Smith R, Blixt A, Bell R, Johansson B, Jordan T, Hitchings RA, Khaw PT, John SW, Carlsson P, Bhattacharya SS. Novel anterior segment phenotypes resulting from forkhead gene alterations: evidence for cross-species conservation of function. Investigative Ophthalmology & Visual Science. 44: 2627-33. PMID 12766066 DOI: 10.1167/Iovs.02-0609  0.315
2003 Libby RT, Smith RS, Savinova OV, Zabaleta A, Martin JE, Gonzalez FJ, John SW. Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. Science (New York, N.Y.). 299: 1578-81. PMID 12624268 DOI: 10.1126/Science.1080095  0.34
2002 Gould DB, John SW. Anterior segment dysgenesis and the developmental glaucomas are complex traits. Human Molecular Genetics. 11: 1185-93. PMID 12015278  0.599
2002 Kim HS, Lee G, John SW, Maeda N, Smithies O. Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proceedings of the National Academy of Sciences of the United States of America. 99: 4602-7. PMID 11904385 DOI: 10.1073/Pnas.072083799  0.483
2002 Anderson MG, Smith RS, Hawes NL, Zabaleta A, Chang B, Wiggs JL, John SW. Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice. Nature Genetics. 30: 81-5. PMID 11743578 DOI: 10.1038/ng794  0.39
2001 Chang B, Smith RS, Peters M, Savinova OV, Hawes NL, Zabaleta A, Nusinowitz S, Martin JE, Davisson ML, Cepko CL, Hogan BL, John SW. Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure. Bmc Genetics. 2: 18. PMID 11722794 DOI: 10.1186/1471-2156-2-18  0.458
2001 Savinova OV, Sugiyama F, Martin JE, Tomarev SI, Paigen BJ, Smith RS, John SW. Intraocular pressure in genetically distinct mice: an update and strain survey. Bmc Genetics. 2: 12. PMID 11532192 DOI: 10.1186/1471-2156-2-12  0.414
2001 Smith RS, Zabaleta A, Savinova OV, John SW. The mouse anterior chamber angle and trabecular meshwork develop without cell death. Bmc Developmental Biology. 1: 3. PMID 11228591 DOI: 10.1186/1471-213X-1-3  0.321
2001 Anderson MG, Smith RS, Savinova OV, Hawes NL, Chang B, Zabaleta A, Wilpan R, Heckenlively JR, Davisson M, John SW. Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice. Bmc Genetics. 2: 1. PMID 11178107 DOI: 10.1186/1471-2156-2-1  0.476
2001 Savinova OV, Sugiyama F, Martin JE, Tomarev SI, Paigen BJ, Smith RS, John SW. Intraocular pressure in genetically distinct mice: an update and strain survey: Correction Bmc Genetics. 2: 16-16. DOI: 10.1186/1471-2156-2-16  0.331
1999 Hawes NL, Smith RS, Chang B, Davisson M, Heckenlively JR, John SW. Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Molecular Vision. 5: 22. PMID 10493779  0.332
1998 Oliver PM, John SW, Purdy KE, Kim R, Maeda N, Goy MF, Smithies O. Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 95: 2547-51. PMID 9482923 DOI: 10.1073/Pnas.95.5.2547  0.475
1997 Savinova OV, Matsukawa N, Smithies O, John SW. Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 788. PMID 9321481 DOI: 10.1007/S003359900571  0.418
1997 MacTaggart TE, Ito M, Smithies O, John SW. Mouse angiotensin receptor genes Agtr1a and Agtr1b map to chromosomes 13 and 3. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 294-5. PMID 9096120 DOI: 10.1007/S003359900419  0.42
1996 John SW, Veress AT, Honrath U, Chong CK, Peng L, Smithies O, Sonnenberg H. Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP. The American Journal of Physiology. 271: R109-14. PMID 8760210  0.458
1995 John SW, Krege JH, Oliver PM, Hagaman JR, Hodgin JB, Pang SC, Flynn TG, Smithies O. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. Science (New York, N.Y.). 267: 679-81. PMID 7839143 DOI: 10.1126/Science.7839143  0.472
1995 Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O'Brien DA, Smithies O. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature. 375: 146-8. PMID 7753170 DOI: 10.1038/375146A0  0.493
1994 Detloff PJ, Lewis J, John SW, Shehee WR, Langenbach R, Maeda N, Smithies O. Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy. Molecular and Cellular Biology. 14: 6936-43. PMID 7935410 DOI: 10.1128/Mcb.14.10.6936  0.68
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