| Year |
Citation |
Score |
| 2017 |
Urban TJ, Nicoletti P, Chalasani N, Serrano J, Stolz A, Daly A, Aithal G, Dillon J, Navarro V, Odin J, Barnhart H, Ostrov D, Long N, Cirulli ET, Watkins PB, et al. Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B∗ 35:02 as a risk factor. Journal of Hepatology. PMID 28323125 DOI: 10.1016/J.Jhep.2017.03.010 |
0.33 |
|
| 2015 |
Wu LS, Rower JE, Burton JR, Anderson PL, Hammond KP, Baouchi-Mokrane F, Everson GT, Urban TJ, D'Argenio DZ, Kiser JJ. Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infection. Antimicrobial Agents and Chemotherapy. 59: 2179-88. PMID 25645847 DOI: 10.1128/Aac.04618-14 |
0.307 |
|
| 2015 |
Lu YF, Goldstein DB, Urban TJ, Bradrick SS. Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden. Virology. 476: 334-40. PMID 25577150 DOI: 10.1016/J.Virol.2014.12.020 |
0.358 |
|
| 2014 |
Urban TJ, Daly AK, Aithal GP. Genetic basis of drug-induced liver injury: present and future. Seminars in Liver Disease. 34: 123-33. PMID 24879978 DOI: 10.1055/S-0034-1375954 |
0.424 |
|
| 2014 |
Urban TJ, Goldstein DB. Pharmacogenetics at 50: genomic personalization comes of age. Science Translational Medicine. 6: 220ps1. PMID 24452261 DOI: 10.1126/Scitranslmed.3005237 |
0.366 |
|
| 2014 |
Köck K, Ferslew BC, Netterberg I, Yang K, Urban TJ, Swaan PW, Stewart PW, Brouwer KL. Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 665-74. PMID 24154606 DOI: 10.1124/Dmd.113.054304 |
0.365 |
|
| 2013 |
Clark PJ, Aghemo A, Degasperi E, Galmozzi E, Urban TJ, Vock DM, Patel K, Thompson AJ, Rumi MG, D'Ambrosio R, Muir AJ, Colombo M. Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy. Journal of Viral Hepatitis. 20: 858-66. PMID 24304455 DOI: 10.1111/Jvh.12113 |
0.315 |
|
| 2013 |
Ko DC, Urban TJ. Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS. Plos Pathogens. 9: e1003424. PMID 23935492 DOI: 10.1371/Journal.Ppat.1003424 |
0.398 |
|
| 2013 |
Urban TJ. Whole-genome sequencing in pharmacogenetics. Pharmacogenomics. 14: 345-8. PMID 23438878 DOI: 10.2217/Pgs.12.211 |
0.375 |
|
| 2012 |
Wei R, Yang F, Urban TJ, Li L, Chalasani N, Flockhart DA, Liu W. Impact of the Interaction between 3'-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes. Frontiers in Genetics. 3: 248. PMID 23181071 DOI: 10.3389/Fgene.2012.00248 |
0.369 |
|
| 2012 |
Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe'er I, et al. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenetics and Genomics. 22: 784-95. PMID 22968431 DOI: 10.1097/Fpc.0B013E3283589A76 |
0.349 |
|
| 2012 |
Zhu Q, Ge D, Heinzen EL, Dickson SP, Urban TJ, Zhu M, Maia JM, He M, Zhao Q, Shianna KV, Goldstein DB. Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium. American Journal of Human Genetics. 91: 422-34. PMID 22939045 DOI: 10.1016/J.Ajhg.2012.07.010 |
0.408 |
|
| 2012 |
Urban TJ, Goldstein DB, Watkins PB. Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here? Pharmacogenomics. 13: 735-8. PMID 22594502 DOI: 10.2217/Pgs.12.45 |
0.355 |
|
| 2012 |
Clark PJ, Thompson AJ, Zhu Q, Vock DM, Zhu M, Patel K, Harrison SA, Naggie S, Ge D, Tillmann HL, Urban TJ, Shianna K, Fellay J, Goodman Z, Noviello S, et al. The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection. Digestive Diseases and Sciences. 57: 2213-21. PMID 22543885 DOI: 10.1007/S10620-012-2171-Y |
0.33 |
|
| 2012 |
Clark PJ, Thompson AJ, Zhu M, Vock DM, Zhu Q, Ge D, Patel K, Harrison SA, Urban TJ, Naggie S, Fellay J, Tillmann HL, Shianna K, Noviello S, Pedicone LD, et al. Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Journal of Viral Hepatitis. 19: 332-40. PMID 22497812 DOI: 10.1111/J.1365-2893.2011.01553.X |
0.331 |
|
| 2012 |
McCormack M, Urban TJ, Shianna KV, Walley N, Pandolfo M, Depondt C, Chaila E, O'Conner GD, Kasperavičiūtė D, Radtke RA, Heinzen EL, Sisodiya SM, Delanty N, Cavalleri GL. Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. Pharmacogenomics. 13: 399-405. PMID 22379998 DOI: 10.2217/Pgs.11.165 |
0.318 |
|
| 2012 |
Cirulli ET, Urban TJ, Marino SE, Linney KN, Birnbaum AK, Depondt C, Attix DK, Radtke RA, Goldstein DB. Genetic and environmental correlates of topiramate-induced cognitive impairment. Epilepsia. 53: e5-8. PMID 22091778 DOI: 10.1111/J.1528-1167.2011.03322.X |
0.323 |
|
| 2012 |
Thompson AJ, Clark PJ, Singh A, Ge D, Fellay J, Zhu M, Zhu Q, Urban TJ, Patel K, Tillmann HL, Naggie S, Afdhal NH, Jacobson IM, Esteban R, Poordad F, et al. Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Journal of Hepatology. 56: 313-9. PMID 21703177 DOI: 10.1016/J.Jhep.2011.04.021 |
0.325 |
|
| 2012 |
Clark PJ, Thompson AJ, Zhu Q, Vock DM, Zhu M, Patel K, Harrison SA, Naggie S, Ge D, Tillmann HL, Urban TJ, Shianna K, Fellay J, Goodman Z, Noviello S, et al. Erratum to: The Association of Genetic Variants with Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C Infection Digestive Diseases and Sciences. 57: 2479-2479. DOI: 10.1007/S10620-012-2309-Y |
0.328 |
|
| 2011 |
Hitomi Y, Cirulli ET, Fellay J, McHutchison JG, Thompson AJ, Gumbs CE, Shianna KV, Urban TJ, Goldstein DB. Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function Gastroenterology. 140: 1314-1321. PMID 21199653 DOI: 10.1053/J.Gastro.2010.12.038 |
0.387 |
|
| 2011 |
Urban T, Shen Y, Chalasani NP, Fontana RJ, Rochon J, Stolz A, Serrano JA, Aithal GP, Daly A, Dillon JF, Floratos A, Molokhia M, Lucena MI, Goldstein DB, Watkins PB. A Genome-Wide Association Study Identifies Potential Susceptibility Loci for Hepatotoxicity Due to Various Drugs Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63683-4 |
0.425 |
|
| 2010 |
Urban TJ, Thompson AJ, Bradrick SS, Fellay J, Schuppan D, Cronin KD, Hong L, McKenzie A, Patel K, Shianna KV, McHutchison JG, Goldstein DB, Afdhal N. IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. Hepatology (Baltimore, Md.). 52: 1888-96. PMID 20931559 DOI: 10.1002/Hep.23912 |
0.334 |
|
| 2010 |
Thompson AJ, Fellay J, Patel K, Tillmann HL, Naggie S, Ge D, Urban TJ, Shianna KV, Muir AJ, Fried MW, Afdhal NH, Goldstein DB, McHutchison JG. Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction. Gastroenterology. 139: 1181-9. PMID 20547162 DOI: 10.1053/J.Gastro.2010.06.016 |
0.314 |
|
| 2010 |
Urban TJ. Race, ethnicity, ancestry, and pharmacogenetics. The Mount Sinai Journal of Medicine, New York. 77: 133-9. PMID 20309922 DOI: 10.1002/Msj.20168 |
0.412 |
|
| 2010 |
Chaudhry AS, Urban TJ, Lamba JK, Birnbaum AK, Remmel RP, Subramanian M, Strom S, You JH, Kasperaviciute D, Catarino CB, Radtke RA, Sisodiya SM, Goldstein DB, Schuetz EG. CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. The Journal of Pharmacology and Experimental Therapeutics. 332: 599-611. PMID 19855097 DOI: 10.1124/Jpet.109.161026 |
0.377 |
|
| 2009 |
Fellay J, Ge D, Shianna KV, Colombo S, Ledergerber B, Cirulli ET, Urban TJ, Zhang K, Gumbs CE, Smith JP, Castagna A, Cozzi-Lepri A, De Luca A, Easterbrook P, Günthard HF, et al. Common genetic variation and the control of HIV-1 in humans. Plos Genetics. 5: e1000791. PMID 20041166 DOI: 10.1371/Journal.Pgen.1000791 |
0.405 |
|
| 2009 |
Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, Heinzen EL, Qiu P, Bertelsen AH, Muir AJ, Sulkowski M, McHutchison JG, Goldstein DB. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 461: 399-401. PMID 19684573 DOI: 10.1038/Nature08309 |
0.328 |
|
| 2009 |
McBride BF, Yang T, Liu K, Urban TJ, Giacomini KM, Kim RB, Roden DM. The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel. Journal of Cardiovascular Pharmacology. 54: 63-71. PMID 19528813 DOI: 10.1097/Fjc.0B013E3181Abc288 |
0.569 |
|
| 2009 |
Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, Urban TJ, Chen L, Yee SW, Choi JH, Huang Y, Brett CM, Burchard EG, Giacomini KM. Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin. Pharmacogenetics and Genomics. 19: 497-504. PMID 19483665 DOI: 10.1097/Fpc.0B013E32832Cc7E9 |
0.783 |
|
| 2009 |
Tahara H, Yee SW, Urban TJ, Hesselson S, Castro RA, Kawamoto M, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Giacomini KM. Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5). The Journal of Pharmacology and Experimental Therapeutics. 329: 262-71. PMID 19141711 DOI: 10.1124/Jpet.108.146449 |
0.655 |
|
| 2008 |
Ge D, Zhang K, Need AC, Martin O, Fellay J, Urban TJ, Telenti A, Goldstein DB. WGAViewer: software for genomic annotation of whole genome association studies. Genome Research. 18: 640-3. PMID 18256235 DOI: 10.1101/Gr.071571.107 |
0.326 |
|
| 2008 |
Cropp CD, Komori T, Shima JE, Urban TJ, Yee SW, More SS, Giacomini KM. Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP. Molecular Pharmacology. 73: 1151-8. PMID 18216183 DOI: 10.1124/Mol.107.043117 |
0.746 |
|
| 2008 |
Urban TJ, Brown C, Castro RA, Shah N, Mercer R, Huang Y, Brett CM, Burchard EG, Giacomini KM. Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin. Clinical Pharmacology and Therapeutics. 83: 416-21. PMID 17609685 DOI: 10.1038/Sj.Clpt.6100271 |
0.663 |
|
| 2007 |
Urban TJ, Yang C, Lagpacan LL, Brown C, Castro RA, Taylor TR, Huang CC, Stryke D, Johns SJ, Kawamoto M, Carlson EJ, Ferrin TE, Burchard EG, Giacomini KM. Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4). Pharmacogenetics and Genomics. 17: 773-82. PMID 17700366 DOI: 10.1097/Fpc.0B013E3281C6D08E |
0.651 |
|
| 2006 |
Urban TJ, Gallagher RC, Brown C, Castro RA, Lagpacan LL, Brett CM, Taylor TR, Carlson EJ, Ferrin TE, Burchard EG, Packman S, Giacomini KM. Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5). Molecular Pharmacology. 70: 1602-11. PMID 16931768 DOI: 10.1124/Mol.106.028126 |
0.68 |
|
| 2006 |
Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, et al. PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters. Pharmacological Reviews. 58: 3-4. PMID 16507878 DOI: 10.1124/Pr.58.1.2 |
0.775 |
|
| 2006 |
Urban TJ, Sebro R, Hurowitz EH, Leabman MK, Badagnani I, Lagpacan LL, Risch N, Giacomini KM. Functional genomics of membrane transporters in human populations. Genome Research. 16: 223-30. PMID 16354753 DOI: 10.1101/Gr.4356206 |
0.753 |
|
| 2006 |
Fujita T, Urban TJ, Leabman MK, Fujita K, Giacomini KM. Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants. Journal of Pharmaceutical Sciences. 95: 25-36. PMID 16307453 DOI: 10.1002/Jps.20536 |
0.79 |
|
| 2006 |
Erdman AR, Mangravite LM, Urban TJ, Lagpacan LL, Castro RA, de la Cruz M, Chan W, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Carlson EJ, Ferrin TE, Brett CM, et al. The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics. American Journal of Physiology. Renal Physiology. 290: F905-12. PMID 16291576 DOI: 10.1152/Ajprenal.00272.2005 |
0.783 |
|
| 2006 |
Urban TJ, Giacomini KM. Organic Cation Transporters Drug Transporters: Molecular Characterization and Role in Drug Disposition. 11-33. DOI: 10.1002/9780470140505.ch2 |
0.545 |
|
| 2005 |
Urban TJ, Giacomini KM, Risch N. Haplotype structure and ethnic-specific allele frequencies at the OCTN locus: implications for the genetics of Crohn's disease. Inflammatory Bowel Diseases. 11: 78-9. PMID 15674120 DOI: 10.1097/00054725-200501000-00014 |
0.557 |
|
| 2004 |
Gray JH, Mangravite LM, Owen RP, Urban TJ, Chan W, Carlson EJ, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, Giacomini KM. Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations. Molecular Pharmacology. 65: 512-9. PMID 14978229 DOI: 10.1124/Mol.65.3.512 |
0.782 |
|
| 2003 |
Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/Pnas.0730857100 |
0.784 |
|
| 2003 |
Gray J, Owen R, Urban T, Giacomini K. Functional characterization of genetic variants of the nucleoside transporter, CNT1 Clinical Pharmacology & Therapeutics. 73: P59-P59. DOI: 10.1016/S0009-9236(03)90574-1 |
0.765 |
|
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