Eric Lander, Ph.D. - Related publications

1986-2004 Whitehead Institute, Cambridge, MA, United States 
 2004- Broad Institute, Cambridge, MA, United States 
Human genome
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Picart-Picolo A, Grob S, Picault N, Franek M, Llauro C, Halter T, Maier TR, Jobet E, Descombin J, Zhang P, Paramasivan V, Baum TJ, Navarro L, Dvořáčková M, Mirouze M, et al. Large tandem duplications affect gene expression, 3D organization, and plant-pathogen response. Genome Research. PMID 33033057 DOI: 10.1101/gr.261586.120   
2020 Fan G, Liu X, Sun S, Shi C, Du X, Han K, Yang B, Fu Y, Liu M, Seim I, Zhang H, Xu Q, Wang J, Su X, Shao L, et al. The Chromosome Level Genome and Genome-wide Association Study for the Agronomic Traits of . Iscience. 23: 101538. PMID 33083766 DOI: 10.1016/j.isci.2020.101538   
2020 Wright BW, Ruan J, Molloy MP, Jaschke PR. Genome Modularization Reveals Overlapped Gene Topology Is Necessary for Efficient Viral Reproduction. Acs Synthetic Biology. PMID 33044064 DOI: 10.1021/acssynbio.0c00323   
2020 Al Mahdi HB, Edris S, Bahieldin A, Al-Aama JY, Elango R, Jamalalail BA, Sabbagh HJ. Identification of Causative Variants Contributing to Nonsyndromic Orofacial Clefts Using Whole-Exome Sequencing in a Saudi Family. Genetic Testing and Molecular Biomarkers. PMID 33121284 DOI: 10.1089/gtmb.2019.0233   
2020 Goel N, Singh S, Aseri TC. Global sequence features based translation initiation site prediction in human genomic sequences. Heliyon. 6: e04825. PMID 32964155 DOI: 10.1016/j.heliyon.2020.e04825   
2020 Ko G, Jang I, Koo N, Park SJ, Oh SH, Kim MS, Choi JH, Kim H, Sim YM, Byeon I, Kim PG, Kim KY, Yoon JC, Mun KL, Lee B, et al. Prometheus, an omics portal for interkingdom comparative genomic analyses. Plos One. 15: e0240191. PMID 33112870 DOI: 10.1371/journal.pone.0240191   
2020 Morard M, Ibáñez C, Adam AC, Querol A, Barrio E, Toft C. Genomic instability in an interspecific hybrid of the genus : a matter of adaptability. Microbial Genomics. PMID 33021926 DOI: 10.1099/mgen.0.000448   
2020 Wong KHY, Ma W, Wei CY, Yeh EC, Lin WJ, Wang EHF, Su JP, Hsieh FJ, Kao HJ, Chen HH, Chow SK, Young E, Chu C, Poon A, Yang CF, et al. Towards a reference genome that captures global genetic diversity. Nature Communications. 11: 5482. PMID 33127893 DOI: 10.1038/s41467-020-19311-w   
2020 Zhao S, Luo J, Zeng X, Li K, Yuan R, Zhu L, Li X, Wu G, Yan X. Rolling Circle Amplification (RCA)-Mediated Genome-Wide ihpRNAi Mutant Library Construction in . International Journal of Molecular Sciences. 21. PMID 33008068 DOI: 10.3390/ijms21197243   
2020 Ntasis VF, Panousis NI, Tektonidou MG, Dermitzakis ET, Boumpas DT, Bertsias GK, Nikolaou C. Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus. Scientific Reports. 10: 16648. PMID 33024230 DOI: 10.1038/s41598-020-73654-4   
2020 Ntasis VF, Panousis NI, Tektonidou MG, Dermitzakis ET, Boumpas DT, Bertsias GK, Nikolaou C. Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus. Scientific Reports. 10: 16648. PMID 33024230 DOI: 10.1038/s41598-020-73654-4   
2020 Hao W, Suo F, Lin Q, Chen Q, Zhou L, Liu Z, Cui W, Zhou Z. Design and Construction of Portable CRISPR-Cpf1-Mediated Genome Editing in 168 Oriented Toward Multiple Utilities. Frontiers in Bioengineering and Biotechnology. 8: 524676. PMID 32984297 DOI: 10.3389/fbioe.2020.524676   
2020 Zhang W, Yang M, Zhou M, Wang Y, Wu X, Zhang X, Ding Y, Zhao G, Yin Z, Wang C. Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig. Frontiers in Genetics. 11: 566255. PMID 33093844 DOI: 10.3389/fgene.2020.566255   
2020 Zhang J, Liu J, McGillivray P, Yi C, Lochovsky L, Lee D, Gerstein M. NIMBus: a negative binomial regression based Integrative Method for mutation Burden Analysis. Bmc Bioinformatics. 21: 474. PMID 33092526 DOI: 10.1186/s12859-020-03758-1   
2020 Beer PA, Cooke SL, Chang DK, Biankin AV. Defining the clinical genomic landscape for real-world precision oncology. Genomics. PMID 33144218 DOI: 10.1016/j.ygeno.2020.10.032   
2020 Yi XG, Yu XQ, Chen J, Zhang M, Liu SW, Zhu H, Li M, Duan YF, Chen L, Wu L, Zhu S, Sun ZS, Liu XH, Wang XR. The genome of Chinese flowering cherry () provides new insights into species. Horticulture Research. 7: 165. PMID 33082971 DOI: 10.1038/s41438-020-00382-1   
2020 Wang G, Anastassiou D. Pan-cancer driver copy number alterations identified by joint expression/CNA data analysis. Scientific Reports. 10: 17199. PMID 33057153 DOI: 10.1038/s41598-020-74276-6   
2020 Berger E, Yorukoglu D, Zhang L, Nyquist SK, Shalek AK, Kellis M, Numanagić I, Berger B. Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets. Nature Communications. 11: 4662. PMID 32938926 DOI: 10.1038/s41467-020-18320-z   
2020 De Oliveira R, Rimbert H, Balfourier F, Kitt J, Dynomant E, Vrána J, Doležel J, Cattonaro F, Paux E, Choulet F. Structural Variations Affecting Genes and Transposable Elements of Chromosome 3B in Wheats. Frontiers in Genetics. 11: 891. PMID 33014014 DOI: 10.3389/fgene.2020.00891   
2020 Groß C, Bortoluzzi C, de Ridder D, Megens HJ, Groenen MAM, Reinders M, Bosse M. Prioritizing sequence variants in conserved non-coding elements in the chicken genome using chCADD. Plos Genetics. 16: e1009027. PMID 32966296 DOI: 10.1371/journal.pgen.1009027   
2020 Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, ... , ... , et al. High-depth African genomes inform human migration and health. Nature. 586: 741-748. PMID 33116287 DOI: 10.1038/s41586-020-2859-7   
2020 Calderano SG, Nishiyama Junior MY, Marini M, Nunes NO, Reis MDS, Patané JSL, da Silveira JF, da Cunha JPC, Elias MC. Identification of Novel Interspersed DNA Repetitive Elements in the Genome Associated with the 3'UTRs of Surface Multigenic Families. Genes. 11. PMID 33096822 DOI: 10.3390/genes11101235   
2020 Alaei-Mahabadi B, Elliott K, Larsson E. Systematic investigation of promoter substitutions resulting from somatic intrachromosomal structural alterations in diverse human cancers. Scientific Reports. 10: 18176. PMID 33097743 DOI: 10.1038/s41598-020-74420-2   
2020 Beecroft SJ, Lamont PJ, Edwards S, Goullée H, Davis MR, Laing NG, Ravenscroft G. The Impact of Next-Generation Sequencing on the Diagnosis, Treatment, and Prevention of Hereditary Neuromuscular Disorders. Molecular Diagnosis & Therapy. PMID 32997275 DOI: 10.1007/s40291-020-00495-2   
2020 Liu EM, Martinez-Fundichely A, Bollapragada R, Spiewack M, Khurana E. CNCDatabase: a database of non-coding cancer drivers. Nucleic Acids Research. PMID 33095860 DOI: 10.1093/nar/gkaa915   
2020 Lee DJ, Kwon T, Kim CK, Seol YJ, Park DS, Lee TH, Ahn BO. NGS_SNPAnalyzer: a desktop software supporting genome projects by identifying and visualizing sequence variations from next-generation sequencing data. Genes & Genomics. PMID 32980993 DOI: 10.1007/s13258-020-00997-7   
2020 Hu Y, Mao B, Xia Y, Peng Y, Zhang D, Tang L, Shao Y, Li Y, Zhao B. Spike-Stalk Injection Method Causes Extensive Phenotypic and Genotypic Variations for Rice Germplasm. Frontiers in Plant Science. 11: 575373. PMID 33101344 DOI: 10.3389/fpls.2020.575373   
2020 Payseur BA, Jing P. Genomic Targets of Positive Selection in Giant Mice from Gough Island. Molecular Biology and Evolution. PMID 33022034 DOI: 10.1093/molbev/msaa255   
2020 De Luca A, Esposito Abate R, Rachiglio AM, Maiello MR, Esposito C, Schettino C, Izzo F, Nasti G, Normanno N. FGFR Fusions in Cancer: From Diagnostic Approaches to Therapeutic Intervention. International Journal of Molecular Sciences. 21. PMID 32962091 DOI: 10.3390/ijms21186856   
2020 Bussotti G, Benkahla A, Jeddi F, Souiaï O, Aoun K, Späth GF, Bouratbine A. Nuclear and mitochondrial genome sequencing of North-African isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype. Microbial Genomics. PMID 32975503 DOI: 10.1099/mgen.0.000444   
2020 Han B, Yi J, Dai J, Zheng T, Gu F, Zhao Q, Zhu F, Song X, Deng H, Wei P, Song C, Liu D, Jiang X, Wang F, Chen Y, et al. A chromosome-level genome assembly of Dendrobium huoshanense using long reads and Hi-C data. Genome Biology and Evolution. PMID 33045048 DOI: 10.1093/gbe/evaa215   
2020 McDaniels JM, Huckaby AC, Carter SA, Lingeman S, Francis A, Congdon M, Santos W, Rathod PK, Guler JL. Extra-chromosomal DNA amplicons in antimalarial resistant Plasmodium falciparum. Molecular Microbiology. PMID 33053232 DOI: 10.1111/mmi.14624   
2020 He S, Dong X, Zhang G, Fan W, Duan S, Shi H, Li D, Li R, Chen G, Long G, Zhao Y, Chen M, Yan M, Yang J, Lu Y, et al. High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae. Molecular Ecology Resources. PMID 32985109 DOI: 10.1111/1755-0998.13257   
2020 Rogers MF, Gaunt TR, Campbell C. Prediction of driver variants in the cancer genome via machine learning methodologies. Briefings in Bioinformatics. PMID 33094325 DOI: 10.1093/bib/bbaa250   
2020 Lei Y, Yang L, Jiang H, Chen J, Sun N, Lv W, He S. Recent genome duplications facilitate the phenotypic diversity of Hb repertoire in the Cyprinidae. Science China. Life Sciences. PMID 33051703 DOI: 10.1007/s11427-020-1809-0   
2020 Rellstab C, Zoller S, Sailer C, Tedder A, Gugerli F, Shimizu KK, Holderegger R, Widmer A, Fischer MC. Genomic signatures of convergent adaptation to Alpine environments in three Brassicaceae species. Molecular Ecology. PMID 32969558 DOI: 10.1111/mec.15648   
2020 Kumar J, Sen Gupta D. Prospects of next generation sequencing in lentil breeding. Molecular Biology Reports. PMID 33037962 DOI: 10.1007/s11033-020-05891-9   
2020 Raue S, Fan SH, Rosenstein R, Zabel S, Luqman A, Nieselt K, Götz F. The Genome of O47. Frontiers in Microbiology. 11: 2061. PMID 32983045 DOI: 10.3389/fmicb.2020.02061   
2020 Wu ZC, Feng HX, Wu L, Zhang M, Zhou WL. Quorum Sensing System in Strain Identified by Genome Sequence Analysis. Acs Omega. 5: 27502-27513. PMID 33134713 DOI: 10.1021/acsomega.0c03986   
2020 Hong MJ, Kim JB, Seo YW, Kim DY. F-Box Genes in the Wheat Genome and Expression Profiling in Wheat at Different Developmental Stages. Genes. 11. PMID 33007852 DOI: 10.3390/genes11101154   
2020 Su W, Zuo T, Peterson T. Ectopic Expression of a Maize Gene Is Induced by Composite Insertions Generated Through Alternative Transposition. Genetics. PMID 32988986 DOI: 10.1534/genetics.120.303592   
2020 Liu H, Hu H, Zhang S, Jin J, Liang X, Huang B, Wang L. The complete chloroplast genome of the rare species and comparative analysis with related species. Physiology and Molecular Biology of Plants : An International Journal of Functional Plant Biology. 26: 2075-2083. PMID 33088051 DOI: 10.1007/s12298-020-00882-3   
2020 Zachariadis V, Cheng H, Andrews N, Enge M. A Highly Scalable Method for Joint Whole-Genome Sequencing and Gene-Expression Profiling of Single Cells. Molecular Cell. PMID 33068522 DOI: 10.1016/j.molcel.2020.09.025   
2020 Xia B, Amador G, Viswanatha R, Zirin J, Mohr SE, Perrimon N. CRISPR-based engineering of gene knockout cells by homology-directed insertion in polyploid Drosophila S2R+ cells. Nature Protocols. 15: 3478-3498. PMID 32958931 DOI: 10.1038/s41596-020-0383-8   
2020 Jiang K, Miao LY, Wang ZW, Ni ZY, Hu C, Zeng XH, Huang WC. Chloroplast Genome Analysis of Two Medicinal spp. (Orchidaceae) Shed Light on the Genetic Information, Comparative Genomics, and Species Identification. Plants (Basel, Switzerland). 9. PMID 33050285 DOI: 10.3390/plants9101332   
2020 Kumar R, Register K, Christopher-Hennings J, Moroni P, Gioia G, Garcia-Fernandez N, Nelson J, Jelinski MD, Lysnyansky I, Bayles D, Alt D, Scaria J. Population Genomic Analysis of Elucidates Geographical Variations and Genes associated with Host-Types. Microorganisms. 8. PMID 33050495 DOI: 10.3390/microorganisms8101561   
2020 Ruzicka F, Dutoit L, Czuppon P, Jordan CY, Li XY, Olito C, Runemark A, Svensson EI, Yazdi HP, Connallon T. The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics. Evolution Letters. 4: 398-415. PMID 33014417 DOI: 10.1002/evl3.192   
2020 Mullins AJ, Jones C, Bull MJ, Webster G, Parkhill J, Connor TR, Murray JAH, Challis GL, Mahenthiralingam E. Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery. Microbiology Resource Announcements. 9. PMID 33060263 DOI: 10.1128/MRA.00485-20   
2020 Hölzer M, Barf LM, Lamkiewicz K, Vorimore F, Lataretu M, Favaroni A, Schnee C, Laroucau K, Marz M, Sachse K. Comparative Genome Analysis of 33 Strains Reveals Characteristic Features of and Closely Related Species. Pathogens (Basel, Switzerland). 9. PMID 33126635 DOI: 10.3390/pathogens9110899   
2020 Walsh T, Casadei S, Munson KM, Eng M, Mandell JB, Gulsuner S, King MC. CRISPR-Cas9/long-read sequencing approach to identify cryptic mutations in and other tumour suppressor genes. Journal of Medical Genetics. PMID 33060287 DOI: 10.1136/jmedgenet-2020-107320