Michele I. Vitolo, Ph.D. - Publications

Affiliations: 
2004 University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Biochemistry, Molecular Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Stemberger MB, Ju JA, Thompson KN, Mathias TJ, Jerrett AE, Chang KT, Ory EC, Annis DA, Mull ML, Gilchrist DE, Vitolo MI, Martin SS. Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes. Cells. 12. PMID 37174666 DOI: 10.3390/cells12091266  0.313
2023 Mull ML, Pratt SJP, Thompson KN, Annis DA, Gad AA, Lee RM, Chang KT, Stemberger MB, Ju JA, Gilchrist DE, Boyman L, Vitolo MI, Lederer WJ, Martin SS. Metastatic breast cancer cells have reduced calcium and actin response after ATP-P2Y2 signaling. Biorxiv : the Preprint Server For Biology. PMID 37034765 DOI: 10.1101/2023.03.31.533191  0.339
2023 Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers. 15. PMID 36765843 DOI: 10.3390/cancers15030884  0.303
2022 Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers. 14. PMID 35406479 DOI: 10.3390/cancers14071707  0.412
2022 Thompson KN, Ju JA, Ory EC, Pratt SJP, Lee RM, Mathias TJ, Chang KT, Lee CJ, Goloubeva OG, Bailey PC, Chakrabarti KR, Jewell CM, Vitolo MI, Martin SS. Microtubule disruption reduces metastasis more effectively than primary tumor growth. Breast Cancer Research : Bcr. 24: 13. PMID 35164808 DOI: 10.1186/s13058-022-01506-2  0.323
2021 Lee RM, Vitolo MI, Losert W, Martin SS. Distinct roles of tumor associated mutations in collective cell migration. Scientific Reports. 11: 10291. PMID 33986306 DOI: 10.1038/s41598-021-89130-6  0.359
2021 Bhandary L, Bailey PC, Chang KT, Underwood KF, Lee CJ, Whipple RA, Jewell CM, Ory E, Thompson KN, Ju JA, Mathias TM, Pratt SJP, Vitolo MI, Martin SS. Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation. Scientific Reports. 11: 3214. PMID 33547369 DOI: 10.1038/s41598-021-81919-9  0.378
2020 Ju JA, Lee CJ, Thompson KN, Ory EC, Lee RM, Mathias TJ, Pratt SJP, Vitolo MI, Jewell CM, Martin SS. Partial thermal imidization of polyelectrolyte multilayer cell tethering surfaces (TetherChip) enables efficient cell capture and microtentacle fixation for circulating tumor cell analysis. Lab On a Chip. PMID 32744284 DOI: 10.1039/D0Lc00207K  0.437
2020 Suryo Rahmanto Y, Shen W, Shi X, Chen X, Yu Y, Yu ZC, Miyamoto T, Lee MH, Singh V, Asaka R, Shimberg G, Vitolo MI, Martin SS, Wirtz D, Drapkin R, et al. Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming. Nature Communications. 11: 2717. PMID 32483112 DOI: 10.1038/S41467-020-16416-0  0.434
2020 Mathias TJ, Chang KT, Martin SS, Vitolo MI. Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs). Cancers. 12. PMID 32245166 DOI: 10.3390/Cancers12030743  0.437
2020 Pratt SJ, Lee RM, Hernandez-Ochoa EO, Ory EC, Thompson KN, Bailey PC, Mathias TJ, Ju JA, Vitolo MI, Schneider MF, Stains JP, Ward CW, Martin SS. Abstract 2575: Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+ signals that are inhibited by oncogenic KRas Immunology. 80: 2575-2575. DOI: 10.1158/1538-7445.Am2020-2575  0.42
2019 Yankaskas CL, Thompson KN, Paul CD, Vitolo MI, Mistriotis P, Mahendra A, Bajpai VK, Shea DJ, Manto KM, Chai AC, Varadarajan N, Kontrogianni-Konstantopoulos A, Martin SS, Konstantopoulos K. A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens. Nature Biomedical Engineering. PMID 31061459 DOI: 10.1038/S41551-019-0400-9  0.436
2019 Linthicum W, Ho Thanh M, Vitolo MI, Wen Q. Effects of PTEN Loss and Activated KRAS Overexpression on Viscoelasticity of Breast Epithelial Cells Biophysical Journal. 116: 412a. DOI: 10.1016/J.Bpj.2018.11.2221  0.422
2018 Bailey PC, Lee RM, Vitolo MI, Pratt SJP, Ory E, Chakrabarti K, Lee CJ, Thompson KN, Martin SS. Single-Cell Tracking of Breast Cancer Cells Enables Prediction of Sphere Formation from Early Cell Divisions. Iscience. 8: 29-39. PMID 30268511 DOI: 10.1016/J.Isci.2018.08.015  0.418
2018 Pratt SJP, Hernández-Ochoa EO, Lee RM, Ory EC, Lyons JS, Joca HC, Johnson A, Thompson K, Bailey P, Lee CJ, Mathias T, Vitolo MI, Trudeau M, Stains JP, Ward CW, et al. Real-time scratch assay reveals mechanisms of early calcium signaling in breast cancer cells in response to wounding. Oncotarget. 9: 25008-25024. PMID 29861849 DOI: 10.18632/Oncotarget.25186  0.414
2018 Linthicum W, Thanh MH, Vitolo MI, Wen Q. Effects of PTEN Loss and Activated KRAS Overexpression on Mechanical Properties of Breast Epithelial Cells. International Journal of Molecular Sciences. 19. PMID 29848992 DOI: 10.3390/Ijms19061613  0.515
2018 Lusche DF, Buchele EC, Russell KB, Soll BA, Vitolo MI, Klemme MR, Wessels DJ, Soll DR. Overexpressing (), a homolog of the human tumor suppressor gene , rescues the abnormal phenotype of the mutant. Oncotarget. 9: 21100-21121. PMID 29765523 DOI: 10.18632/Oncotarget.24941  0.397
2018 Yu Y, Suryo Rahmanto Y, Lee MH, Wu PH, Phillip JM, Huang CH, Vitolo MI, Gaillard S, Martin SS, Wirtz D, Shih IM, Wang TL. Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. Oncogene. PMID 29643476 DOI: 10.1038/S41388-018-0241-0  0.514
2018 Rahmanto YS, Shi X, Shen W, Miyamoto T, Yu Y, Chen X, Lee M, Singh V, Vitolo MI, Wirtz D, Drapkin R, Xuan J, Shih I, Wang T. Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry Cancer Research. 78: 2493-2493. DOI: 10.1158/1538-7445.Am2018-2493  0.41
2016 Hessler LK, Boggs AE, Whipple RA, Vitolo MI, Chakrabarti KR, Bhandary L, Thompson KN, Martin SS. Abstract LB-342: HDAC inhibition promotes tubulin-independent cancer cell migration Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-342  0.492
2015 Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence. Oncotarget. PMID 26497685 DOI: 10.18632/Oncotarget.6159  0.506
2015 Chakrabarti KR, Whipple RA, Boggs AE, Hessler LK, Bhandary L, Vitolo MI, Thompson K, Martin SS. Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment. Oncotarget. PMID 26431377 DOI: 10.18632/Oncotarget.5345  0.503
2015 Bhandary L, Whipple RA, Vitolo MI, Charpentier MS, Boggs AE, Chakrabarti KR, Thompson KN, Martin SS. ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells. Oncotarget. 6: 6251-66. PMID 25749040 DOI: 10.18632/Oncotarget.3360  0.517
2015 Boggs AE, Vitolo MI, Whipple RA, Charpentier MS, Goloubeva OG, Ioffe OB, Tuttle KC, Slovic J, Lu Y, Mills GB, Martin SS. α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration. Cancer Research. 75: 203-15. PMID 25503560 DOI: 10.1158/0008-5472.Can-13-3563  0.425
2015 Shriver M, Stroka KM, Vitolo MI, Martin S, Huso DL, Konstantopoulos K, Kontrogianni-Konstantopoulos A. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis Oncogene. 34: 4248-4259. PMID 25381817 DOI: 10.1038/Onc.2014.358  0.511
2015 Thompson KN, Whipple RA, Charpentier MS, Boggs AE, Bhandray L, Chakrabarti KR, Martin SS, Vitolo MI. Abstract A32: Cell dormancy and tumorigenicity due to PTEN loss Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-A32  0.51
2015 Thompson KN, Whipple RA, Yoon JR, Charpentier MS, Boggs AE, Bhandary L, Chakrabarti KR, Martin SS, Vitolo MI. Abstract 2161: Activation of the MAPK pathway in combination with PTEN loss leads to aggressive primary tumor formation Cancer Research. 75: 2161-2161. DOI: 10.1158/1538-7445.Am2015-2161  0.515
2015 Bhandary L, Whipple RA, Vitolo MI, Charpentier MS, Boggs AE, Chakrabarti KR, Thompson KN, Martin SS. ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells Oncotarget. 6: 6251-6266.  0.339
2014 Perry NA, Vitolo MI, Martin SS, Kontrogianni-Konstantopoulos A. Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells. Oncotarget. 5: 8558-68. PMID 25261370 DOI: 10.18632/Oncotarget.2338  0.54
2014 Hartman KG, Vitolo MI, Pierce AD, Fox JM, Shapiro P, Martin SS, Wilder PT, Weber DJ. Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK. The Journal of Biological Chemistry. 289: 12886-95. PMID 24627490 DOI: 10.1074/Jbc.M114.561613  0.621
2014 Charpentier MS, Whipple RA, Vitolo MI, Boggs AE, Slovic J, Thompson KN, Bhandary L, Martin SS. Curcumin targets breast cancer stem-like cells with microtentacles that persist in mammospheres and promote reattachment Cancer Research. 74: 1250-1260. PMID 24371229 DOI: 10.1158/0008-5472.Can-13-1778  0.474
2014 Bhandary L, Vitolo MI, Bettes RA, Charpentier MS, Boggs AE, Slovic J, Thompson K, Martin SS. Abstract 3160: ROCK inhibition promotes microtentacle formation and reattachment of breast cancer cells Cancer Research. 74: 3160-3160. DOI: 10.1158/1538-7445.Am2014-3160  0.551
2013 Whipple RA, Vitolo MI, Boggs AE, Charpentier MS, Thompson K, Martin SS. Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition Breast Cancer Research. 15. PMID 24028602 DOI: 10.1186/Bcr3477  0.47
2013 Vitolo MI, Boggs AE, Whipple RA, Yoon JR, Thompson K, Matrone MA, Cho EH, Balzer EM, Martin SS. Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin. Oncogene. 32: 2200-10. PMID 22689060 DOI: 10.1038/Onc.2012.234  0.5
2013 Charpentier MS, Bettes RA, Vitolo MI, Boggs AE, Slovic J, Thompson K, Bhandary L, Yoon J, Martin SS. Abstract 3772: The role of microtentacles in the metastatic potential of breast tumor stem cells. Cancer Research. 73: 3772-3772. DOI: 10.1158/1538-7445.Am2013-3772  0.477
2013 Slovic J, Vitolo MI, Whipple RA, Boggs AE, Charpentier MS, Bhandary L, Thompson K, Martin SS. Abstract 276: Microtentacle stabilization during TGFβ-induced EMT as a new therapeutic target to reduce circulating tumor cell metastasis. Cancer Research. 73: 276-276. DOI: 10.1158/1538-7445.Am2013-276  0.539
2013 Boggs AE, Vitolo MI, Bettes RA, Slovic J, Charpentier MS, Martin SS. Abstract 2627: Acetylation of α-tubulin contributes to microtentacle formation and re-attachment in suspended breast tumor cells. Cancer Research. 73: 2627-2627. DOI: 10.1158/1538-7445.Am2013-2627  0.477
2013 Chakrabarti K, Whipple RA, Boggs AE, Charpentier MS, Slovic J, Vitolo MI, Martin SS. Abstract 1480: The effect of Metformin on microtentacle formation and stabilization in breast cancer cells. Cancer Research. 73: 1480-1480. DOI: 10.1158/1538-7445.Am2013-1480  0.471
2012 Pierce AD, Anglin IE, Vitolo MI, Mochin MT, Underwood KF, Goldblum SE, Kommineni S, Passaniti A. Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotype. Journal of Cellular Biochemistry. 113: 282-92. PMID 21913213 DOI: 10.1002/Jcb.23354  0.701
2012 Hartman KG, Vitolo MI, Wilder PT, Fox J, Shapiro P, Martin SS, Weber DJ. Abstract 2164: S100B affects MAPK signaling in malignant melanoma via a direct interaction with RSK Cancer Research. 72: 2164-2164. DOI: 10.1158/1538-7445.Am2012-2164  0.475
2011 House RP, Pozzuto M, Patel P, Dulyaninova NG, Li ZH, Zencheck WD, Vitolo MI, Weber DJ, Bresnick AR. Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion. Biochemistry. 50: 6920-32. PMID 21721535 DOI: 10.1021/Bi200498Q  0.436
2011 Li HF, Keeton A, Vitolo M, Maddox C, Rasmussen L, Hobrath J, White EL, Park BH, Piazza GA, Kim JS, Waldman T. A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces apoptosis in PTEN and PIK3CA mutant human cancer cells. Journal of Biomolecular Screening. 16: 383-93. PMID 21335596 DOI: 10.1177/1087057110397357  0.458
2011 Vitolo MI, Boggs AE, Thompson K, Whipple RA, Yoon JR, Slovic J, Charpentier MS, Matrone MA, Martin SS. Abstract 3122: PTEN loss disrupts the actin cortex to promote tubulin microtentacle formation and increased metastatic potential Cancer Research. 71: 3122-3122. DOI: 10.1158/1538-7445.Am2011-3122  0.511
2011 Gianni K, Vitolo MI, Wilder PT, Martin SS, Weber DJ. Abstract 1054: S100B affects cell signaling in malignant melanoma Cancer Research. 71: 1054-1054. DOI: 10.1158/1538-7445.Am2011-1054  0.474
2010 Whipple RA, Matrone MA, Cho EH, Balzer EM, Vitolo MI, Yoon JR, Ioffe OB, Tuttle KC, Yang J, Martin SS. Epithelial-to-mesenchymal transition promotes tubulin detyrosination and microtentacles that enhance endothelial engagement. Cancer Research. 70: 8127-37. PMID 20924103 DOI: 10.1158/0008-5472.Can-09-4613  0.49
2010 Weiss MB, Vitolo MI, Mohseni M, Rosen DM, Denmeade SR, Park BH, Weber DJ, Bachman KE. Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response. Oncogene. 29: 4715-24. PMID 20562907 DOI: 10.1038/Onc.2010.220  0.421
2010 Matrone MA, Whipple RA, Thompson K, Cho EH, Vitolo MI, Balzer EM, Yoon JR, Ioffe OB, Tuttle KC, Tan M, Martin SS. Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells. Oncogene. 29: 3217-27. PMID 20228842 DOI: 10.1038/Onc.2010.68  0.474
2010 Gianni K, Wilder PT, Vitolo MI, Shapiro P, Weber DJ. Abstract 4125: The effects of S100B on cell signaling in malignant melanoma Cancer Research. 70: 4125-4125. DOI: 10.1158/1538-7445.Am10-4125  0.449
2010 Whipple RA, Matrone MA, Cho EH, Balzer EM, Tuttle KC, Vitolo MI, Yoon JR, Ioffe OB, Yang J, Martin SS. Abstract 1464: EMT-induced tubulin detyrosination can be inhibited with parthenolide, reducing microtentacles and the lung retention of circulating breast tumor cells Cancer Research. 70: 1464-1464. DOI: 10.1158/1538-7445.Am10-1464  0.431
2010 Vitolo MI, Thompson K, Whipple-Bettes RA, Matrone MA, Yoon JR, Balzer EM, Cho EH, Martin SS. Abstract 1123: PTEN loss increases efficiency of breast tumor metastasis Cancer Research. 70: 1123-1123. DOI: 10.1158/1538-7445.Am10-1123  0.376
2009 Higgins MJ, Abukhdeir AM, Gustin J, Vitolo MI, Bachman KE, Park BH. Preclinical study of lithium sensitivity in human breast PTEN knock out cell lines. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e14641. PMID 27964232 DOI: 10.1200/Jco.2009.27.15_Suppl.E14641  0.467
2009 Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, Park BH, Martin SS, Weber DJ, Bachman KE. Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. Cancer Research. 69: 8275-83. PMID 19843859 DOI: 10.1158/0008-5472.Can-09-1067  0.504
2009 Gustin JP, Karakas B, Weiss MB, Abukhdeir AM, Lauring J, Garay JP, Cosgrove D, Tamaki A, Konishi H, Konishi Y, Mohseni M, Wang G, Rosen DM, Denmeade SR, Higgins MJ, Vitolo MI, et al. Knockin of mutant PIK3CA activates multiple oncogenic pathways. Proceedings of the National Academy of Sciences of the United States of America. 106: 2835-40. PMID 19196980 DOI: 10.1073/Pnas.0813351106  0.484
2008 Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, et al. Tamoxifen-stimulated growth of breast cancer due to p21 loss. Proceedings of the National Academy of Sciences of the United States of America. 105: 288-93. PMID 18162533 DOI: 10.1073/Pnas.0710887105  0.452
2007 Karakas B, Weeraratna AT, Abukhdeir AM, Konishi H, Gustin JP, Vitolo MI, Bachman KE, Park BH. P21 gene knock down does not identify genetic effectors seen with gene knock out. Cancer Biology & Therapy. 6: 1025-30. PMID 17611398 DOI: 10.4161/Cbt.6.7.4202  0.388
2007 Vitolo MI, Anglin IE, Mahoney WM, Renoud KJ, Gartenhaus RB, Bachman KE, Passaniti A. The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation. Cancer Biology & Therapy. 6: 856-63. PMID 17438369 DOI: 10.4161/Cbt.6.6.4241  0.656
2007 Weiss MB, Vitolo MI, Baerenfaller K, Marra G, Park BH, Bachman KE. Persistent mismatch repair deficiency following targeted correction of hMLH1. Cancer Gene Therapy. 14: 98-104. PMID 17082796 DOI: 10.1038/Sj.Cgt.7700997  0.394
2006 Reinert LS, Shi B, Nandi S, Mazan-Mamczarz K, Vitolo M, Bachman KE, He H, Gartenhaus RB. MCT-1 protein interacts with the cap complex and modulates messenger RNA translational profiles. Cancer Research. 66: 8994-9001. PMID 16982740 DOI: 10.1158/0008-5472.Can-06-1999  0.348
2006 Abukhdeir AM, Blair BG, Brenner K, Karakas B, Konishi H, Lim J, Sahasranaman V, Huang Y, Keen J, Davidson N, Vitolo MI, Bachman KE, Park BH. Physiologic estrogen receptor alpha signaling in non-tumorigenic human mammary epithelial cells. Breast Cancer Research and Treatment. 99: 23-33. PMID 16541319 DOI: 10.1007/S10549-006-9177-0  0.448
2004 Vucenik I, Passaniti A, Vitolo MI, Tantivejkul K, Eggleton P, Shamsuddin AM. Anti-angiogenic activity of inositol hexaphosphate (IP6). Carcinogenesis. 25: 2115-23. PMID 15297368 DOI: 10.1093/Carcin/Bgh232  0.649
2004 Sun L, Vitolo MI, Qiao M, Anglin IE, Passaniti A. Regulation of TGFbeta1-mediated growth inhibition and apoptosis by RUNX2 isoforms in endothelial cells. Oncogene. 23: 4722-34. PMID 15107836 DOI: 10.1038/Sj.Onc.1207589  0.667
2003 Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA. Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. Oncogene. 22: 2334-42. PMID 12700668 DOI: 10.1038/Sj.Onc.1206330  0.639
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