| Year |
Citation |
Score |
| 2024 |
Zhao J, Cato LD, Arora UP, Bao EL, Bryant SC, Williams N, Jia Y, Goldman SR, Nangalia J, Erb MA, Vos SM, Armstrong SA, Sankaran VG. Inherited blood cancer predisposition through altered transcription elongation. Cell. PMID 38218188 DOI: 10.1016/j.cell.2023.12.016 |
0.32 |
|
| 2023 |
Akbari P, Vuckovic D, Stefanucci L, Jiang T, Kundu K, Kreuzhuber R, Bao EL, Collins JH, Downes K, Grassi L, Guerrero JA, Kaptoge S, Knight JC, Meacham S, Sambrook J, ... ... Sankaran VG, et al. A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology. Nature Communications. 14: 5023. PMID 37596262 DOI: 10.1038/s41467-023-40679-y |
0.311 |
|
| 2023 |
Martin-Rufino JD, Castano N, Pang M, Grody EI, Joubran S, Caulier A, Wahlster L, Li T, Qiu X, Riera-Escandell AM, Newby GA, Al'Khafaji A, Chaudhary S, Black S, Weng C, ... ... Sankaran VG, et al. Massively parallel base editing to map variant effects in human hematopoiesis. Cell. PMID 37137305 DOI: 10.1016/j.cell.2023.03.035 |
0.345 |
|
| 2023 |
Cato LD, Li R, Lu HY, Yu F, Wissman M, Mkumbe BS, Ekwattanakit S, Deelen P, Mwita L, Sangeda RZ, Suksangpleng T, Riolueang S, Bronson PG, Paul DS, Kawabata E, ... ... Sankaran VG, et al. Genetic regulation of fetal hemoglobin across global populations. Medrxiv : the Preprint Server For Health Sciences. PMID 36993312 DOI: 10.1101/2023.03.24.23287659 |
0.338 |
|
| 2023 |
Lu HY, Orkin SH, Sankaran VG. Fetal Hemoglobin Regulation in Beta-Thalassemia. Hematology/Oncology Clinics of North America. 37: 301-312. PMID 36907604 DOI: 10.1016/j.hoc.2022.12.002 |
0.458 |
|
| 2023 |
Gundry M, Sankaran VG. Hacking hematopoiesis - emerging tools for examining variant effects. Disease Models & Mechanisms. 16. PMID 36826849 DOI: 10.1242/dmm.049857 |
0.317 |
|
| 2022 |
Voit RA, Tao L, Yu F, Cato LD, Cohen B, Fleming TJ, Antoszewski M, Liao X, Fiorini C, Nandakumar SK, Wahlster L, Teichert K, Regev A, Sankaran VG. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nature Immunology. 24: 69-83. PMID 36522544 DOI: 10.1038/s41590-022-01370-4 |
0.304 |
|
| 2022 |
Sankaran VG, Weissman JS, Zon LI. Cellular barcoding to decipher clonal dynamics in disease. Science (New York, N.Y.). 378: eabm5874. PMID 36227997 DOI: 10.1126/science.abm5874 |
0.448 |
|
| 2022 |
Yu F, Cato LD, Weng C, Liggett LA, Jeon S, Xu K, Chiang CWK, Wiemels JL, Weissman JS, de Smith AJ, Sankaran VG. Variant to function mapping at single-cell resolution through network propagation. Biorxiv : the Preprint Server For Biology. PMID 35118467 DOI: 10.1101/2022.01.23.477426 |
0.301 |
|
| 2022 |
Ludwig L, Lareau CA, Bao EL, Liu N, Utsugisawa T, Tseng AM, Myers SA, Verboon JM, Ulirsch JC, Luo W, Muus C, Fiorini C, Olive ME, Vockley CM, Munschauer M, ... ... Sankaran VG, et al. A Congenital Anemia Reveals Distinct Targeting Mechanisms for Master Transcription Factor GATA1. Blood. PMID 35030251 DOI: 10.1182/blood.2021013753 |
0.484 |
|
| 2021 |
Caulier AL, Sankaran VG. Molecular and cellular mechanisms that regulate human erythropoiesis. Blood. PMID 34936695 DOI: 10.1182/blood.2021011044 |
0.313 |
|
| 2021 |
Shen Y, Li R, Teichert K, Montbleau KE, Verboon JM, Voit RA, Sankaran VG. Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing. Plos Genetics. 17: e1009835. PMID 34634037 DOI: 10.1371/journal.pgen.1009835 |
0.311 |
|
| 2021 |
Shen Y, Verboon JM, Zhang Y, Liu N, Kim YJ, Marglous S, Nandakumar SK, Voit RA, Fiorini C, Ejaz A, Basak A, Orkin SH, Xu J, Sankaran VG. A unified model of human hemoglobin switching through single-cell genome editing. Nature Communications. 12: 4991. PMID 34404810 DOI: 10.1038/s41467-021-25298-9 |
0.525 |
|
| 2020 |
Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, ... ... Sankaran VG, et al. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12. PMID 33087503 DOI: 10.1126/scitranslmed.abb5831 |
0.453 |
|
| 2020 |
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, ... ... Sankaran VG, et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33057201 DOI: 10.1038/s41586-020-2819-2 |
0.31 |
|
| 2020 |
Liggett LA, Sankaran VG. Unraveling Hematopoiesis through the Lens of Genomics. Cell. 182: 1384-1400. PMID 32946781 DOI: 10.1016/J.Cell.2020.08.030 |
0.36 |
|
| 2020 |
Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, ... ... Sankaran VG, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008 |
0.428 |
|
| 2020 |
Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, ... ... Sankaran VG, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045 |
0.331 |
|
| 2020 |
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, ... ... Sankaran VG, et al. Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nature Biotechnology. PMID 32788668 DOI: 10.1038/S41587-020-0645-6 |
0.36 |
|
| 2020 |
Liggett LA, Voit RA, Sankaran VG. Sowing the Seeds of Clonal Hematopoiesis. Cell Stem Cell. 27: 195-197. PMID 32763180 DOI: 10.1016/J.Stem.2020.07.011 |
0.362 |
|
| 2020 |
Nandakumar SK, Liao X, Sankaran VG. In The Blood: Connecting Variant to Function In Human Hematopoiesis. Trends in Genetics : Tig. PMID 32534791 DOI: 10.1016/J.Tig.2020.05.006 |
0.419 |
|
| 2020 |
Verboon JM, Mahmut D, Kim AR, Nakamura M, Abdulhay NJ, Nandakumar SK, Gupta N, Akie TE, Geddis AE, Manes B, Kapp ME, Hofmann I, Gabriel SB, Klein DE, Williams DA, ... ... Sankaran VG, et al. Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction. Journal of Clinical Immunology. PMID 32303876 DOI: 10.1007/S10875-020-00778-7 |
0.431 |
|
| 2020 |
Gianferante DM, Wlodarski MW, Atsidaftos E, Da Costa L, Delaporta P, Farrar JE, Goldman FD, Hussain M, Kattamis A, Leblanc T, Lipton JM, Niemeyer CM, Pospisilova D, Quarello P, Ramenghi U, ... Sankaran VG, et al. Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A. Haematologica. PMID 32241839 DOI: 10.3324/Haematol.2020.246629 |
0.363 |
|
| 2020 |
Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, ... ... Sankaran VG, et al. Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation. Nature Genetics. PMID 31959994 DOI: 10.1038/S41588-019-0568-7 |
0.548 |
|
| 2019 |
Lareau CA, Ludwig LS, Sankaran VG. Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking. Blood Advances. 3: 4161-4165. PMID 31841597 DOI: 10.1182/Bloodadvances.2019001196 |
0.377 |
|
| 2019 |
Justice MJ, Hmeljak J, Sankaran VG, Socolovsky M, Zon LI. From blood development to disease: a paradigm for clinical translation. Disease Models & Mechanisms. PMID 31836582 DOI: 10.1242/Dmm.043661 |
0.468 |
|
| 2019 |
Bao EL, Cheng AN, Sankaran VG. The genetics of human hematopoiesis and its disruption in disease. Embo Molecular Medicine. e10316. PMID 31313878 DOI: 10.15252/Emmm.201910316 |
0.453 |
|
| 2019 |
Cheng AN, Bao EL, Fiorini C, Sankaran VG. Macrothrombocytopenia associated with a rare GFI1B missense variant confounding the presentation of immune thrombocytopenia. Pediatric Blood & Cancer. e27874. PMID 31207059 DOI: 10.1002/Pbc.27874 |
0.365 |
|
| 2019 |
Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Reports. 27: 3228-3240.e7. PMID 31189107 DOI: 10.1016/J.Celrep.2019.05.046 |
0.438 |
|
| 2019 |
Sankaran VG. A chance encounter changes everything. Nature Medicine. PMID 31171867 DOI: 10.1038/S41591-019-0418-2 |
0.328 |
|
| 2019 |
Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, ... Sankaran VG, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. Elife. 8. PMID 31070582 DOI: 10.7554/Elife.44080 |
0.439 |
|
| 2019 |
Zhang S, Macias-Garcia A, Ulirsch JC, Velazquez J, Butty VL, Levine SS, Sankaran VG, Chen JJ. HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis. Elife. 8. PMID 31033440 DOI: 10.7554/Elife.46976 |
0.3 |
|
| 2019 |
Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, ... ... Sankaran VG, et al. Impaired human hematopoiesis due to a cryptic intronic splicing mutation. The Journal of Experimental Medicine. PMID 30914438 DOI: 10.1084/Jem.20181625 |
0.406 |
|
| 2019 |
Liang L, Peng Y, Zhang J, Zhang Y, Roy M, Han X, Xiao X, Sun S, Liu H, Nie L, Kuang Y, Zhu Z, Deng J, Xia Y, Sankaran VG, et al. Deubiquitylase USP7 regulates human terminal erythroid differentiation by stabilizing GATA1. Haematologica. PMID 30872372 DOI: 10.3324/Haematol.2018.206227 |
0.367 |
|
| 2019 |
Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG. Interrogation of human hematopoiesis at single-cell and single-variant resolution. Nature Genetics. PMID 30858613 DOI: 10.1038/S41588-019-0362-6 |
0.438 |
|
| 2019 |
Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, ... ... Sankaran VG, et al. Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics. Cell. PMID 30827679 DOI: 10.1016/J.Cell.2019.01.022 |
0.41 |
|
| 2019 |
Bao EL, Lareau CA, Brugnara C, Fulcher I, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG. Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort. American Journal of Hematology. PMID 30680775 DOI: 10.1002/Ajh.25421 |
0.369 |
|
| 2019 |
Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, ... Sankaran VG, et al. Author response: Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis Elife. DOI: 10.7554/Elife.44080.041 |
0.381 |
|
| 2018 |
Ulirsch JC, Verboon JM, Kazerounian S, Guo MH, Yuan D, Ludwig LS, Handsaker RE, Abdulhay NJ, Fiorini C, Genovese G, Lim ET, Cheng A, Cummings BB, Chao KR, Beggs AH, ... ... Sankaran VG, et al. The Genetic Landscape of Diamond-Blackfan Anemia. American Journal of Human Genetics. PMID 30503522 DOI: 10.1016/J.Ajhg.2018.10.027 |
0.382 |
|
| 2018 |
Montbleau KE, Sankaran VG. A chance to cut (the genome) is a chance to cure. Blood. 131: 1884-1885. PMID 29699995 DOI: 10.1182/Blood-2018-03-839787 |
0.327 |
|
| 2018 |
Khajuria RK, Munschauer M, Ulirsch JC, Fiorini C, Ludwig LS, McFarland SK, Abdulhay NJ, Specht H, Keshishian H, Mani DR, Jovanovic M, Ellis SR, Fulco CP, Engreitz JM, Schütz S, ... ... Sankaran VG, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. PMID 29551269 DOI: 10.1016/J.Cell.2018.02.036 |
0.45 |
|
| 2018 |
Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 mRNA translation. The Journal of Clinical Investigation. PMID 29408805 DOI: 10.1172/Jci94956 |
0.392 |
|
| 2018 |
Choudhuri A, Trompouki E, Abraham BJ, Colli L, Mallard W, Yang M, Vinjamur D, Ghamari A, Nandakumar S, Hoi K, Hummel B, Boatman S, Chan V, Bowman TV, Yang S, ... ... Sankaran VG, et al. Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits Blood. 132: 1277-1277. DOI: 10.1182/Blood-2018-99-118637 |
0.552 |
|
| 2018 |
Basak A, Munschauer M, Ulirsch JC, Montbleau KE, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, Narla M, ... ... Sankaran VG, et al. Control of Human Hemoglobin Switching By LIN28B-Mediated Regulation of BCL11A Translation Blood. 132: 412-412. DOI: 10.1182/Blood-2018-99-117440 |
0.574 |
|
| 2018 |
Giri N, Gianferante M, Atsidaftos E, Wlodarski MW, Quarello P, Volejnikova J, Delaporta P, Sankaran VG, Farrar JE, Hussain M, McReynolds LJ, Kattamis A, Lipton JM, Niemeyer C, Pospisilova D, et al. Phenotypes of Diamond Blackfan Anemia Patients with RPL35A Haploinsufficiency Due to 3q29 Deletion Compared with RPL35A Single Nucleotide Variants or Small Insertion/Deletions Blood. 132: 3854-3854. DOI: 10.1182/Blood-2018-99-117171 |
0.324 |
|
| 2018 |
Bao EL, Ulirsch JC, Lareau CA, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG. Dissecting the Regulation of Human Hematopoiesis at Single-Cell and Single-Variant Resolution Blood. 132: 531-531. DOI: 10.1182/Blood-2018-99-112624 |
0.456 |
|
| 2018 |
Abdulhay N, Verboon J, Ulirsch J, Zieger B, Mi X, Obeng E, Erlacher M, Gupta N, Gabriel S, Ebert B, Niemeyer C, Khoriaty R, Ancliff P, Gazda H, Wlodarski M, ... Sankaran V, et al. A Cryptic Intronic GATA1 Splicing Mutation Provides Insights Into Human Hematopoietic Differentiation Experimental Hematology. 64: S53. DOI: 10.1016/J.Exphem.2018.06.185 |
0.353 |
|
| 2017 |
Kim AR, Sankaran VG. Thrombopoietin: tickling the HSC's fancy. Embo Molecular Medicine. PMID 29191946 DOI: 10.15252/Emmm.201708450 |
0.407 |
|
| 2017 |
Fiorini C, Abdulhay NJ, McFarland SK, Munschauer M, Ulirsch JC, Chiarle R, Sankaran VG. Developmentally-Faithful and Effective Human Erythropoiesis in Immunodeficient and Kit Mutant Mice. American Journal of Hematology. PMID 28568895 DOI: 10.1002/Ajh.24805 |
0.393 |
|
| 2017 |
Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Abdulhay NJ, King DS, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, ... ... Sankaran VG, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 168: 1053-1064.e15. PMID 28283061 DOI: 10.1016/J.Cell.2017.02.026 |
0.314 |
|
| 2016 |
Guo MH, Nandakumar SK, Ulirsch JC, Zekavat SM, Buenrostro JD, Natarajan P, Salem RM, Chiarle R, Mitt M, Kals M, Pärn K, Fischer K, Milani L, Mägi R, Palta P, ... ... Sankaran VG, et al. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Proceedings of the National Academy of Sciences of the United States of America. PMID 28031487 DOI: 10.1073/Pnas.1619052114 |
0.432 |
|
| 2016 |
Han X, Zhang J, Peng Y, Peng M, Chen X, Chen H, Song J, Hu X, Ye M, Li J, Sankaran VG, Hillyer CD, Mohandas N, An X, Liu J. Unexpected role for p19INK4d in post-transcriptional regulation of GATA1 and modulation of human terminal erythropoiesis. Blood. PMID 27879259 DOI: 10.1182/Blood-2016-09-739268 |
0.33 |
|
| 2016 |
Ludwig LS, Khajuria RK, Sankaran VG. Emerging cellular and gene therapies for congenital anemias. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 27792859 DOI: 10.1002/Ajmg.C.31529 |
0.402 |
|
| 2016 |
Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... Sankaran VG, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 785. PMID 27588453 DOI: 10.1016/J.Ajhg.2016.08.002 |
0.406 |
|
| 2016 |
Abdulhay N, Fiorini C, Kumánovics A, Sun AA, Hansen-Rejali J, Voelkerding KV, Rosenzweig SD, Hill HR, Sankaran VG. Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutations. Blood. PMID 27581358 DOI: 10.1182/Blood-2016-08-731943 |
0.395 |
|
| 2016 |
Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, et al. The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. Nature Communications. 7: 12353. PMID 27507172 DOI: 10.1038/Ncomms12353 |
0.392 |
|
| 2016 |
Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... Sankaran VG, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 481-488. PMID 27486782 DOI: 10.1016/J.Ajhg.2016.06.016 |
0.422 |
|
| 2016 |
Liddicoat BJ, Hartner JC, Piskol R, Ramaswami G, Chalk AM, Kingsley PD, Sankaran VG, Wall M, Purton LE, Seeburg PH, Palis J, Orkin SH, Lu J, Li JB, Walkley CR. Adenosine-to-insoine RNA editing by ADAR1 is essential for normal murine erythropoiesis. Experimental Hematology. PMID 27373493 DOI: 10.1016/J.Exphem.2016.06.250 |
0.477 |
|
| 2016 |
Kim AR, Sankaran VG. Development of autologous blood cell therapies. Experimental Hematology. PMID 27345108 DOI: 10.1016/J.Exphem.2016.06.005 |
0.359 |
|
| 2016 |
Capellera-Garcia S, Pulecio J, Dhulipala K, Siva K, Rayon-Estrada V, Singbrant S, Sommarin MN, Walkley CR, Soneji S, Karlsson G, Raya Á, Sankaran VG, Flygare J. Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion. Cell Reports. PMID 27264182 DOI: 10.1016/J.Exphem.2016.06.075 |
0.403 |
|
| 2016 |
Ulirsch JC, Nandakumar SK, Wang L, Giani FC, Zhang X, Rogov P, Melnikov A, McDonel P, Do R, Mikkelsen TS, Sankaran VG. Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits. Cell. 165: 1530-1545. PMID 27259154 DOI: 10.1016/J.Cell.2016.04.048 |
0.439 |
|
| 2016 |
Wakabayashi A, Ulirsch JC, Ludwig LS, Fiorini C, Yasuda M, Choudhuri A, McDonel P, Zon LI, Sankaran VG. Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044088 DOI: 10.1073/Pnas.1521754113 |
0.549 |
|
| 2016 |
Basak A, Sankaran VG. Regulation of the fetal hemoglobin silencing factor BCL11A. Annals of the New York Academy of Sciences. PMID 26963603 DOI: 10.1111/Nyas.13024 |
0.453 |
|
| 2016 |
Nandakumar SK, Ulirsch JC, Sankaran VG. Advances in understanding erythropoiesis: evolving perspectives. British Journal of Haematology. PMID 26846448 DOI: 10.1111/Bjh.13938 |
0.445 |
|
| 2016 |
Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, Ozdemir M, Garcia C, ... ... Sankaran VG, et al. Discovery of the First Pathogenic Human EPO Mutation Provides Mechanistic Insight into Cytokine Signaling Blood. 128: 331-331. DOI: 10.1182/Blood.V128.22.331.331 |
0.38 |
|
| 2016 |
Sankaran VG. Hematopoiesis in natura: insight from studies of blood production in humans Experimental Hematology. 44: S36. DOI: 10.1016/J.Exphem.2016.06.034 |
0.318 |
|
| 2015 |
Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, ... ... Sankaran VG, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. PMID 26607381 DOI: 10.1016/J.Stem.2015.09.015 |
0.558 |
|
| 2015 |
Wakabayashi A, Sankaran VG. Society for Pediatric Research 2015 Young Investigator Award: Genetics of human hematopoiesis-What patients can teach us about blood cell production. Pediatric Research. PMID 26575596 DOI: 10.1038/Pr.2015.245 |
0.42 |
|
| 2015 |
Noh JY, Gandre-Babbe S, Wang Y, Hayes V, Yao Y, Gadue P, Sullivan SK, Chou ST, Machlus KR, Italiano JE, Kyba M, Finkelstein D, Ulirsch JC, Sankaran VG, French DL, et al. Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells. The Journal of Clinical Investigation. 125: 2369-74. PMID 25961454 DOI: 10.1172/Jci77670 |
0.403 |
|
| 2015 |
Basak A, Hancarova M, Ulirsch JC, Balci TB, Trkova M, Pelisek M, Vlckova M, Muzikova K, Cermak J, Trka J, Dyment DA, Orkin SH, Daly MJ, Sedlacek Z, Sankaran VG. BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations. The Journal of Clinical Investigation. 125: 2363-8. PMID 25938782 DOI: 10.1172/Jci81163 |
0.561 |
|
| 2015 |
Sankaran VG, Weiss MJ. Anemia: progress in molecular mechanisms and therapies. Nature Medicine. 21: 221-30. PMID 25742458 DOI: 10.1038/Nm.3814 |
0.3 |
|
| 2015 |
Sankaran VG, Ulirsch JC, Tchaikovskii V, Ludwig LS, Wakabayashi A, Kadirvel S, Lindsley RC, Bejar R, Shi J, Lovitch SB, Bishop DF, Steensma DP. X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation. The Journal of Clinical Investigation. 125: 1665-9. PMID 25705881 DOI: 10.1172/Jci78619 |
0.334 |
|
| 2015 |
Ludwig LS, Cho H, Wakabayashi A, Eng JC, Ulirsch JC, Fleming MD, Lodish HF, Sankaran VG. Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis. American Journal of Hematology. 90: 386-91. PMID 25615569 DOI: 10.1002/Ajh.23952 |
0.426 |
|
| 2015 |
Bianchi P, Fermo E, Eng JC, Ulirsch JC, Vercellati C, Braidotti P, Hildick-Smith G, Satchwell TJ, Pellegrin S, Zanella A, Barcellini W, Paw BH, Toye AM, Sankaran VG. Biallelic Mutations in PARP4 Are Linked to a Variant Form of Congenital Dyserythropoietic Anemia Blood. 126: 272-272. DOI: 10.1182/Blood.V126.23.272.272 |
0.391 |
|
| 2015 |
Steinberg Shemer O, Byrska-Bishop M, Ulirsch JC, Abdulmalik O, Yao Y, Kim AR, Gadue P, Kingsley PD, French D, Hardison RC, Palis J, Sankaran VG, Weiss MJ. Temporally Distinct Developmental Waves of Erythropoiesis from Human Pluripotent Stem Cells Blood. 126: 1170-1170. DOI: 10.1182/Blood.V126.23.1170.1170 |
0.365 |
|
| 2014 |
Ulirsch JC, Lacy JN, An X, Mohandas N, Mikkelsen TS, Sankaran VG. Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation. Plos Genetics. 10: e1004890. PMID 25521328 DOI: 10.1371/Journal.Pgen.1004890 |
0.422 |
|
| 2014 |
Ludwig LS, Gazda HT, Eng JC, Eichhorn SW, Thiru P, Ghazvinian R, George TI, Gotlib JR, Beggs AH, Sieff CA, Lodish HF, Lander ES, Sankaran VG. Altered translation of GATA1 in Diamond-Blackfan anemia. Nature Medicine. 20: 748-53. PMID 24952648 DOI: 10.1038/Nm.3557 |
0.381 |
|
| 2014 |
Pishesha N, Thiru P, Shi J, Eng JC, Sankaran VG, Lodish HF. Transcriptional divergence and conservation of human and mouse erythropoiesis. Proceedings of the National Academy of Sciences of the United States of America. 111: 4103-8. PMID 24591581 DOI: 10.1073/Pnas.1401598111 |
0.421 |
|
| 2014 |
Sankaran VG. Post-Transcriptional Defects and Erythroid Pathobiology Blood. 124: SCI-35-SCI-35. DOI: 10.1182/Blood.V124.21.Sci-35.Sci-35 |
0.459 |
|
| 2014 |
Capellera Garcia S, Dhulipala K, Siva K, Rayon Estrada V, Wang E, Hyde G, Singbrant S, Walkley C, Soneji S, Sankaran VG, Flygare J. Direct Lineage Reprogramming of Murine Fibroblasts to Erythroid Progenitor Cells By Defined Factors Blood. 124: 246-246. DOI: 10.1182/Blood.V124.21.246.246 |
0.424 |
|
| 2013 |
Sankaran VG, Joshi M, Agrawal A, Schmitz-Abe K, Towne MC, Marinakis N, Markianos K, Berry GT, Agrawal PB. Rare complete loss of function provides insight into a pleiotropic genome-wide association study locus. Blood. 122: 3845-7. PMID 24288412 DOI: 10.1182/Blood-2013-09-528315 |
0.355 |
|
| 2013 |
Sankaran VG, Gallagher PG. Applications of high-throughput DNA sequencing to benign hematology. Blood. 122: 3575-3582. PMID 24021670 DOI: 10.1182/Blood-2013-07-460337 |
0.346 |
|
| 2013 |
Sankaran VG, Orkin SH. Genome-wide association studies of hematologic phenotypes: A window into human hematopoiesis Current Opinion in Genetics and Development. 23: 339-344. PMID 23477921 DOI: 10.1016/J.Gde.2013.02.006 |
0.53 |
|
| 2013 |
Musallam KM, Taher AT, Cappellini MD, Sankaran VG. Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia. Blood. 121: 2199-2212; quiz 2372. PMID 23315167 DOI: 10.1182/Blood-2012-10-408021 |
0.305 |
|
| 2013 |
Sankaran VG, Orkin SH. The switch from fetal to adult hemoglobin Cold Spring Harbor Perspectives in Medicine. 3. PMID 23209159 DOI: 10.1101/Cshperspect.A011643 |
0.504 |
|
| 2012 |
Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF. Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes & Development. 26: 2075-87. PMID 22929040 DOI: 10.1101/Gad.197020.112 |
0.55 |
|
| 2012 |
Sankaran VG, Ghazvinian R, Do R, Thiru P, Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander ES, Gazda HT. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. The Journal of Clinical Investigation. 122: 2439-43. PMID 22706301 DOI: 10.1172/Jci63597 |
0.518 |
|
| 2011 |
Sankaran VG. Targeted therapeutic strategies for fetal hemoglobin induction. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2011: 459-465. PMID 22160074 DOI: 10.1182/Asheducation-2011.1.459 |
0.402 |
|
| 2011 |
Xu J, Peng C, Sankaran VG, Shao Z, Esrick EB, Chong BG, Ippolito GC, Fujiwara Y, Ebert BL, Tucker PW, Orkin SH. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Science (New York, N.Y.). 334: 993-6. PMID 21998251 DOI: 10.1126/Science.1211053 |
0.528 |
|
| 2011 |
Sankaran VG, Xu J, Byron R, Greisman HA, Fisher C, Weatherall DJ, Sabath DE, Groudine M, Orkin SH, Premawardhena A, Bender MA. A functional element necessary for fetal hemoglobin silencing. The New England Journal of Medicine. 365: 807-14. PMID 21879898 DOI: 10.1056/Nejmoa1103070 |
0.51 |
|
| 2011 |
Sankaran VG, Menne J, Heller R. Heterozygous disruption of human SOX6 is insufficient to impair erythropoiesis or silencing of fetal hemoglobin Blood. 117: 4396-4397. PMID 21511965 DOI: 10.1182/Blood-2010-11-320887 |
0.428 |
|
| 2011 |
Sankaran VG, Menne TF, Šćepanović D, Vergilio JA, Ji P, Kim J, Thiru P, Orkin SH, Lander ES, Lodish HF. MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proceedings of the National Academy of Sciences of the United States of America. 108: 1519-24. PMID 21205891 DOI: 10.1073/Pnas.1018384108 |
0.537 |
|
| 2011 |
Wilber A, Hargrove PW, Kim YS, Riberdy JM, Sankaran VG, Papanikolaou E, Georgomanoli M, Anagnou NP, Orkin SH, Nienhuis AW, Persons DA. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer. Blood. 117: 2817-26. PMID 21156846 DOI: 10.1182/Blood-2010-08-300723 |
0.536 |
|
| 2011 |
Xu J, Peng C, Sankaran VG, Orkin SH. Correction of Murine Sickle Cell Disease Through Interference with Fetal Hemoglobin Silencing Blood. 118: 351-351. DOI: 10.1182/Blood.V118.21.351.351 |
0.504 |
|
| 2010 |
Sankaran VG, Nathan DG. Reversing the hemoglobin switch. The New England Journal of Medicine. 363: 2258-60. PMID 21121839 DOI: 10.1056/Nejmcibr1010767 |
0.379 |
|
| 2010 |
Sankaran VG, Nathan DG. Thalassemia: an overview of 50 years of clinical research. Hematology/Oncology Clinics of North America. 24: 1005-20. PMID 21075277 DOI: 10.1016/J.Hoc.2010.08.009 |
0.32 |
|
| 2010 |
Galarneau G, Palmer CD, Sankaran VG, Orkin SH, Hirschhorn JN, Lettre G. Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation Nature Genetics. 42: 1049-1051. PMID 21057501 DOI: 10.1038/Ng.707 |
0.5 |
|
| 2010 |
Sankaran VG, Lettre G, Orkin SH, Hirschhorn JN. Modifier genes in Mendelian disorders: the example of hemoglobin disorders. Annals of the New York Academy of Sciences. 1214: 47-56. PMID 21039591 DOI: 10.1111/J.1749-6632.2010.05821.X |
0.525 |
|
| 2010 |
Sankaran VG, Xu J, Orkin SH. Transcriptional silencing of fetal hemoglobin by BCL11A. Annals of the New York Academy of Sciences. 1202: 64-8. PMID 20712774 DOI: 10.1111/J.1749-6632.2010.05574.X |
0.574 |
|
| 2010 |
Xu J, Sankaran VG, Ni M, Menne TF, Puram RV, Kim W, Orkin SH. Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6. Genes & Development. 24: 783-98. PMID 20395365 DOI: 10.1101/Gad.1897310 |
0.513 |
|
| 2010 |
Sankaran VG, Xu J, Orkin SH. Advances in the understanding of haemoglobin switching. British Journal of Haematology. 149: 181-94. PMID 20201948 DOI: 10.1111/J.1365-2141.2010.08105.X |
0.511 |
|
| 2010 |
Xu J, Sankaran VG, Esrick EB, Ebert BL, Orkin SH. Reactivation of Silenced Human HbF In Adult Mice by Inactivation of BCL11A Blood. 116: 643-643. DOI: 10.1182/Blood.V116.21.643.643 |
0.46 |
|
| 2009 |
Sankaran VG, Xu J, Ragoczy T, Ippolito GC, Walkley CR, Maika SD, Fujiwara Y, Ito M, Groudine M, Bender MA, Tucker PW, Orkin SH. Developmental and species-divergent globin switching are driven by BCL11A. Nature. 460: 1093-7. PMID 19657335 DOI: 10.1038/Nature08243 |
0.533 |
|
| 2009 |
Xu J, Sankaran VG, Fujiwara Y, Orkin SH. Control of Hemoglobin Switching by BCL11A. Blood. 114: 5-5. DOI: 10.1182/Blood.V114.22.5.5 |
0.49 |
|
| 2008 |
Sankaran VG, Menne TF, Xu J, Akie TE, Lettre G, Van Handel B, Mikkola HK, Hirschhorn JN, Cantor AB, Orkin SH. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science (New York, N.Y.). 322: 1839-42. PMID 19056937 DOI: 10.1126/science.1165409 |
0.557 |
|
| 2008 |
Walkley CR, Sankaran VG, Orkin SH. Rb and hematopoiesis: stem cells to anemia. Cell Division. 3: 13. PMID 18775080 DOI: 10.1186/1747-1028-3-13 |
0.54 |
|
| 2008 |
Lettre G, Sankaran VG, Bezerra MA, Araújo AS, Uda M, Sanna S, Cao A, Schlessinger D, Costa FF, Hirschhorn JN, Orkin SH. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 11869-74. PMID 18667698 DOI: 10.1073/Pnas.0804799105 |
0.472 |
|
| 2008 |
Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes & Development. 22: 1662-76. PMID 18559481 DOI: 10.1101/Gad.1656808 |
0.529 |
|
| 2008 |
Sankaran VG, Orkin SH, Walkley CR. Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis. Genes & Development. 22: 463-75. PMID 18258751 DOI: 10.1182/Blood.V110.11.638.638 |
0.49 |
|
| 2008 |
Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, Chen W, Usala G, Busonero F, Maschio A, Albai G, Piras MG, Sestu N, Lai S, Dei M, Mulas A, et al. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proceedings of the National Academy of Sciences of the United States of America. 105: 1620-5. PMID 18245381 DOI: 10.1073/Pnas.0711566105 |
0.53 |
|
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